MCID: ATR019
MIFTS: 22

Atrial Septal Defect Sinus Venosus

Categories: Cardiovascular diseases, Fetal diseases, Rare diseases

Aliases & Classifications for Atrial Septal Defect Sinus Venosus

MalaCards integrated aliases for Atrial Septal Defect Sinus Venosus:

Name: Atrial Septal Defect Sinus Venosus 52 71
Atrial Septal Defect, Sinus Venosus Type 58
Sinus Venosus Atrial Septal Defects 52
Asd, Sinus Venosus Type 58
Sinus Venosus Asd 52

Classifications:

Orphanet: 58  
Rare cardiac malformations
Developmental anomalies during embryogenesis


External Ids:

MESH via Orphanet 44 C548009
ICD10 via Orphanet 33 Q21.1
UMLS via Orphanet 72 C0344730
Orphanet 58 ORPHA99105
UMLS 71 C0344730

Summaries for Atrial Septal Defect Sinus Venosus

MalaCards based summary : Atrial Septal Defect Sinus Venosus, also known as atrial septal defect, sinus venosus type, is related to sinoatrial node disease and sick sinus syndrome. An important gene associated with Atrial Septal Defect Sinus Venosus is CITED2 (Cbp/P300 Interacting Transactivator With Glu/Asp Rich Carboxy-Terminal Domain 2). Affiliated tissues include heart and lung, and related phenotypes are fatigue and dyspnea

Related Diseases for Atrial Septal Defect Sinus Venosus

Diseases related to Atrial Septal Defect Sinus Venosus via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 47)
# Related Disease Score Top Affiliating Genes
1 sinoatrial node disease 10.7
2 sick sinus syndrome 10.7
3 atrial heart septal defect 10.7
4 heart septal defect 10.7
5 cyanosis, transient neonatal 10.5
6 mitral valve stenosis 10.5
7 pulmonary vein stenosis 10.5
8 progressive familial heart block, type ia 10.4
9 pulmonary hypertension, primary, 1 10.4
10 progressive familial heart block, type ib 10.4
11 atrioventricular block 10.4
12 endocarditis 10.4
13 right bundle branch block 10.4
14 vascular disease 10.4
15 eisenmenger syndrome 10.4
16 interatrial communication 10.4
17 atrial standstill 1 10.2
18 wolff-parkinson-white syndrome 10.2
19 cryptorchidism, unilateral or bilateral 10.2
20 myasthenia gravis 10.2
21 atrioventricular septal defect 10.2
22 peripartum cardiomyopathy 10.2
23 pulmonary hypertension 10.2
24 infective endocarditis 10.2
25 portal hypertension 10.2
26 respiratory failure 10.2
27 pulmonary edema 10.2
28 constrictive pericarditis 10.2
29 hemopericardium 10.2
30 mitral valve insufficiency 10.2
31 pericardial effusion 10.2
32 dilated cardiomyopathy 10.2
33 patent foramen ovale 10.2
34 thrombocytopenia 10.2
35 ventricular septal defect 10.2
36 pericarditis 10.2
37 lutembacher's syndrome 10.2
38 dental caries 10.2
39 tricuspid valve insufficiency 10.2
40 congestive heart failure 10.2
41 aortic arch interruption 10.2
42 atrial septal defect coronary sinus 10.2
43 cor triatriatum 10.2
44 cor triatriatum dexter 10.2
45 pulmonary venous return anomaly 10.2
46 syncope 10.2
47 pulmonary arterial hypertension associated with another disease 10.2

Graphical network of the top 20 diseases related to Atrial Septal Defect Sinus Venosus:



Diseases related to Atrial Septal Defect Sinus Venosus

Symptoms & Phenotypes for Atrial Septal Defect Sinus Venosus

Human phenotypes related to Atrial Septal Defect Sinus Venosus:

58 (show all 27)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 fatigue 58 Frequent (79-30%)
2 dyspnea 58 Occasional (29-5%)
3 congestive heart failure 58 Very rare (<4-1%)
4 pulmonary arterial hypertension 58 Occasional (29-5%)
5 supraventricular arrhythmia 58 Occasional (29-5%)
6 stroke 58 Very rare (<4-1%)
7 atrial fibrillation 58 Occasional (29-5%)
8 right bundle branch block 58 Occasional (29-5%)
9 tricuspid regurgitation 58 Occasional (29-5%)
10 exertional dyspnea 58 Frequent (79-30%)
11 first degree atrioventricular block 58 Occasional (29-5%)
12 anomalous pulmonary venous return 58 Frequent (79-30%)
13 junctional ectopic tachycardia 58 Occasional (29-5%)
14 obstructive lung disease 58 Very rare (<4-1%)
15 thromboembolism 58 Very rare (<4-1%)
16 palpitations 58 Frequent (79-30%)
17 left-to-right shunt 58 Very frequent (99-80%)
18 exercise intolerance 58 Frequent (79-30%)
19 right ventricular dilatation 58 Occasional (29-5%)
20 atrial flutter 58 Occasional (29-5%)
21 cardiac conduction abnormality 58 Frequent (79-30%)
22 supraventricular tachycardia 58 Occasional (29-5%)
23 atrial arrhythmia 58 Occasional (29-5%)
24 premature atrial contractions 58 Occasional (29-5%)
25 systolic heart murmur 58 Frequent (79-30%)
26 paradoxical splitting of the second heart sound 58 Frequent (79-30%)
27 automatic atrial tachycardia 58 Occasional (29-5%)

Drugs & Therapeutics for Atrial Septal Defect Sinus Venosus

Search Clinical Trials , NIH Clinical Center for Atrial Septal Defect Sinus Venosus

Genetic Tests for Atrial Septal Defect Sinus Venosus

Anatomical Context for Atrial Septal Defect Sinus Venosus

MalaCards organs/tissues related to Atrial Septal Defect Sinus Venosus:

40
Heart, Lung

Publications for Atrial Septal Defect Sinus Venosus

Articles related to Atrial Septal Defect Sinus Venosus:

(show all 30)
# Title Authors PMID Year
1
Evolution and Current Results of a Unified Strategy for Sinus Venosus Surgery. 61
32437676 2020
2
Transcatheter Correction of Superior Sinus Venosus Atrial Septal Defects as an Alternative to Surgical Treatment. 61
32192652 2020
3
Heart transplantation using a donor with partial anomalous pulmonary venous connection and atrial septal defect. 61
28379508 2017
4
Persistent left superior vena cava in atrial septal defect sinus venosus type: diagnosis with saline contrast echocardiography-a case series. 61
28469854 2017
5
Sinus venosus atrial septal defect as a cause of palpitations and dyspnea in an adult: a diagnostic imaging challenge. 61
25705227 2015
6
The role of cardiac MRI in the diagnosis and management of sinus venosus atrial septal defect. 61
24987269 2014
7
Individual risk factors and complexity associated with congenital heart disease in a pediatric medicaid cohort. 61
23820317 2013
8
Inferior sinus venosus atrial septal defect. 61
24482952 2013
9
Long-term results of the single-patch repair technique for sinus venosus atrial septal defects. 61
23625482 2013
10
MRI for detection of anomalous pulmonary venous drainage in patients with sinus venosus atrial septal defects. 61
20686854 2011
11
Diagnostic accuracy of multidetector spiral computed tomography for preoperative assessment of sinus venosus atrial septal defects in children. 61
21098509 2011
12
Diagnosis of inferior sinus venosus atrial septal defects using transthoracic three-dimensional echocardiography. 61
19828288 2010
13
Atypical atrial septal defects in children: noninvasive evaluation by cardiac MRI. 61
18787816 2008
14
Arrhythmias in congenital heart defects. 61
17685001 2007
15
Improved visualization of sinus venosus atrial septal defects in adults from the transthoracic approach. 61
16880105 2006
16
[The relationship between rhythm disturbances and incisions in adult sinus venosus atrial septal defects]. 61
14675879 2003
17
Outcome following repair of sinus venosus atrial septal defects in children. 61
12213746 2002
18
[The sinus venosus type of interatrial communication: its diagnosis by transesophageal echocardiography]. 61
10221044 1999
19
Sinus venosus atrial septal defects: surgical follow-up. 61
9105808 1997
20
Echocardiographic imaging techniques with subcostal and right parasternal longitudinal views in detecting sinus venosus atrial septal defects. 61
8849617 1996
21
Sinus venosus defects: unroofing of the right pulmonary veins--anatomic and echocardiographic findings and surgical treatment. 61
8037105 1994
22
Sinus venosus atrial septal defect associated with vein of Galen malformations: report of two cases. 61
8115275 1994
23
[Transthoracic and transesophageal echocardiography in the pre- and postoperative assessment of interatrial communication]. 61
8134694 1993
24
Transoesophageal echocardiographic assessment of primum, secundum and sinus venosus atrial septal defects. 61
1869325 1991
25
Is routine preoperative cardiac catheterization necessary before repair of secundum and sinus venosus atrial septal defects? 61
6736474 1984
26
Identification of atrial septal defects by cross-sectional contrast echocardiography. 61
7426201 1980
27
Atrial septal defect (sinus venosus type) in a dog. 61
7451304 1980
28
Two-dimensional echocardiographic findings in atrial septal defect. 61
884800 1977
29
Operative repair of atrial septal defect without cardiac catheterization. 61
1111680 1975
30
[Posterior "atrial septal defect", "high atrial septal defect", "sinus venosus defect"]. 61
13754236 1961

Variations for Atrial Septal Defect Sinus Venosus

Expression for Atrial Septal Defect Sinus Venosus

Search GEO for disease gene expression data for Atrial Septal Defect Sinus Venosus.

Pathways for Atrial Septal Defect Sinus Venosus

GO Terms for Atrial Septal Defect Sinus Venosus

Sources for Atrial Septal Defect Sinus Venosus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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