MCID: ATR005
MIFTS: 51

Atrophic Gastritis

Categories: Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Atrophic Gastritis

MalaCards integrated aliases for Atrophic Gastritis:

Name: Atrophic Gastritis 12 15
Gastritis, Atrophic 44 73
Gastritis Atrophic 55
Gastric Atrophy 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8929
ICD10 33 K29.4
ICD9CM 35 535.1
MeSH 44 D005757
NCIt 50 C7405
SNOMED-CT 68 84568007
UMLS 73 C0017154

Summaries for Atrophic Gastritis

MalaCards based summary : Atrophic Gastritis, also known as gastritis, atrophic, is related to autoimmune atrophic gastritis and helicobacter pylori infection, and has symptoms including dyspepsia An important gene associated with Atrophic Gastritis is CHGA (Chromogranin A), and among its related pathways/superpathways are Toll Comparative Pathway and IL-17 Family Signaling Pathways. The drugs Hydroxocobalamin and Methylcobalamin have been mentioned in the context of this disorder. Affiliated tissues include testes, thyroid and spleen, and related phenotype is mortality/aging.

Wikipedia : 76 Atrophic gastritis (also known as type A or type B gastritis) is a process of chronic inflammation of... more...

Related Diseases for Atrophic Gastritis

Diseases in the Atrophic Gastritis family:

Autoimmune Atrophic Gastritis

Diseases related to Atrophic Gastritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 222)
# Related Disease Score Top Affiliating Genes
1 autoimmune atrophic gastritis 34.4 CHGA GAST
2 helicobacter pylori infection 31.3 CXCL8 GAST IL1B S100A8
3 gastric ulcer 30.8 CXCL8 GAST IL1B IL1RN
4 gastric cancer 30.7 CDX2 GAST IL1B IL1RN S100A8 TP53
5 peptic esophagitis 30.7 CXCL8 IL1B
6 gastritis 30.5 ADH7 CDX2 CHGA CXCL8 GAST GHRL
7 gastrinoma 30.4 CHGA GAST SST
8 esophagitis 30.4 CXCL8 IL1B TP53
9 neuroendocrine tumor 30.3 CHGA GAST SST
10 duodenal gastrinoma 30.2 CHGA GAST SST
11 zollinger-ellison syndrome 30.2 CHGA GAST SST
12 viral infectious disease 30.0 CXCL8 IL1B TNF
13 gastric neuroendocrine neoplasm 30.0 CHGA GAST SST
14 duodenal ulcer 30.0 CXCL8 GAST IL1B IL1RN S100A8 SST
15 dyspepsia 30.0 CXCL8 GHRL PGC SST
16 arthritis 30.0 CXCL8 IL1B IL1RN TNF
17 peptic ulcer disease 29.9 CXCL8 GAST GHRL IL1B IL1RN S100A8
18 gastroesophageal reflux 29.8 CDX2 CXCL8 GAST GHRL IL1B TP53
19 gastric adenocarcinoma 28.8 CDX2 CHGA CXCL8 GAST IL1B IL1RN
20 megaloblastic anemia 1 11.0
21 pernicious anemia 10.6
22 iron metabolism disease 10.4
23 adenocarcinoma 10.4
24 recurrent corneal erosion 10.3 CXCL8 IL1B
25 bagassosis 10.3 CXCL8 IL1B
26 staphylococcal toxic shock syndrome 10.2 IL1B TNF
27 systemic onset juvenile idiopathic arthritis 10.2 IL1RN TNF
28 pouchitis 10.2 CXCL8 IL1RN
29 juvenile ankylosing spondylitis 10.2 IL1RN TNF
30 tungiasis 10.2 CXCL8 TNF
31 goblet cell carcinoid 10.2 CHGA GAST
32 kashin-beck disease 10.2 IL1B TNF
33 vitamin b12 deficiency 10.2
34 streptococcal toxic-shock syndrome 10.2 CXCL8 TNF
35 scleral disease 10.2 IL1RN TNF
36 rheumatoid lung disease 10.2 IL1B TNF
37 gastric cancer, hereditary diffuse 10.2 IL1B IL1RN
38 pustulosis of palm and sole 10.2 IL1RN TNF
39 vaginal benign neoplasm 10.2 CDX2 CHGA
40 vaginal adenoma 10.2 CDX2 CHGA
41 vaginal tubulovillous adenoma 10.2 CDX2 CHGA
42 vulvar vestibulitis syndrome 10.2 IL1B IL1RN TNF
43 meningitis 10.2 CXCL8 IL1B TNF
44 exudative glomerulonephritis 10.2 CXCL8 IL1B TNF
45 schnitzler syndrome 10.2 IL1B IL1RN
46 periodontitis 10.2 CXCL8 IL1B TNF
47 osteosclerotic myeloma 10.2 IL1B IL1RN TNF
48 burns 10.2 IL1B TNF
49 haemophilus influenzae 10.2 CXCL8 IL1B TNF
50 joint disorders 10.2 IL1B IL1RN TNF

Comorbidity relations with Atrophic Gastritis via Phenotypic Disease Network (PDN): (show all 18)


Active Peptic Ulcer Disease Acute Cystitis
Acute Pancreatitis Anxiety
Bronchitis Chronic Myocardial Ischemia
Deficiency Anemia Duodenitis
Dysthymic Disorder Esophagitis
Heart Disease Hypertension, Essential
Intermediate Coronary Syndrome Iron Deficiency Anemia
Irritable Bowel Syndrome Ischemic Heart Disease
Paralytic Ileus Protein-Energy Malnutrition

Graphical network of the top 20 diseases related to Atrophic Gastritis:



Diseases related to Atrophic Gastritis

Symptoms & Phenotypes for Atrophic Gastritis

UMLS symptoms related to Atrophic Gastritis:


dyspepsia

MGI Mouse Phenotypes related to Atrophic Gastritis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 mortality/aging MP:0010768 9.36 ADH7 CDX2 CHGA GAST IL1B IL1RN

Drugs & Therapeutics for Atrophic Gastritis

Drugs for Atrophic Gastritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 103)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Hydroxocobalamin Approved Phase 4,Not Applicable 13422-51-0 11953898 44475014
2
Methylcobalamin Approved, Experimental, Investigational Phase 4 13422-55-4
3
Amphotericin B Approved, Investigational Phase 4 1397-89-3 5280965 14956
4
Moxifloxacin Approved, Investigational Phase 4 354812-41-2, 151096-09-2 152946
5
Polyestradiol phosphate Approved Phase 4 28014-46-2
6
Tetracycline Approved, Vet_approved Phase 4 60-54-8 5353990
7
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
8
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757
9
Norgestimate Approved, Investigational Phase 4 35189-28-7 6540478
10
Esomeprazole Approved, Investigational Phase 4 161796-78-7, 119141-88-7 4594 9579578
11
Amoxicillin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 26787-78-0 33613
12
Metronidazole Approved Phase 4,Phase 3 443-48-1 4173
13 Estradiol valerate Approved, Investigational, Vet_approved Phase 4 979-32-8
14
Clarithromycin Approved Phase 4,Phase 3,Phase 2,Not Applicable 81103-11-9 84029
15
Pectin Approved, Investigational, Vet_approved Phase 4 9000-69-5 441476
16
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Not Applicable 59-30-3 6037
17
Cyanocobalamin Approved, Nutraceutical Phase 4,Not Applicable 68-19-9 44176380
18
Cobalamin Experimental Phase 4,Not Applicable 13408-78-1 6438156
19 Trace Elements Phase 4,Not Applicable
20 Vitamin B9 Phase 4,Not Applicable
21 Vitamin B Complex Phase 4,Not Applicable
22 Vitamin B 12 Phase 4,Not Applicable
23 Micronutrients Phase 4,Not Applicable
24 Folate Phase 4,Not Applicable
25 Hematinics Phase 4,Not Applicable
26 Vitamins Phase 4,Phase 3,Not Applicable
27 Vitamin B12 Phase 4,Not Applicable
28 Proton Pump Inhibitors Phase 4,Phase 3
29 Liposomal amphotericin B Phase 4
30
Bismuth Phase 4 7440-69-9 16682734 105143
31 Fluoroquinolones Phase 4
32 Anti-Infective Agents Phase 4,Phase 3,Phase 2
33 Nucleic Acid Synthesis Inhibitors Phase 4
34 Estradiol 3-benzoate Phase 4
35 Antiprotozoal Agents Phase 4,Phase 3,Phase 2
36 Topoisomerase Inhibitors Phase 4
37 Antiparasitic Agents Phase 4,Phase 3,Phase 2
38 Estradiol 17 beta-cypionate Phase 4
39 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2
40 Contraceptives, Oral Phase 4
41 Anti-Ulcer Agents Phase 4,Phase 3,Not Applicable
42 Contraceptives, Oral, Combined Phase 4
43 Antacids Phase 4,Phase 3,Not Applicable
44 Contraceptive Agents Phase 4
45 Gastrointestinal Agents Phase 4,Phase 3,Not Applicable
46 Norgestimate, ethinyl estradiol drug combination Phase 4
47
Omeprazole Approved, Investigational, Vet_approved Phase 3,Phase 2,Not Applicable 73590-58-6 4594
48
Guaifenesin Approved, Investigational, Vet_approved Phase 3 93-14-1 3516
49
Selenium Approved, Investigational, Vet_approved Phase 3 7782-49-2
50
Tocopherol Approved, Investigational Phase 3 1406-66-2 14986

Interventional clinical trials:

(show top 50) (show all 51)
# Name Status NCT ID Phase Drugs
1 To Evaluate the Efficacy and Safety of Vitamin B12 Contains Extract of Lamb's Stomach in Treatment of Chronic Atrophic Gastritis (CAG) Completed NCT01474044 Phase 4 Gastropylor Complex Capsules
2 Long-term Follow up Helicobacter Pylori Reinfection Rate After Second-Line Treatment: Bismuth-Containing Quadruple Therapy Versus Moxifloxacin-Based Triple Therapy Completed NCT01792700 Phase 4 esomeprazole;tripotassium dicitrate bismuthate;metronidazole;tetracycline;moxifloxacin;amoxicillin
3 Multicentric Randomized Study of H. Pylori Eradication and Pepsinogen Testing for Prevention of Gastric Cancer Mortality Recruiting NCT02047994 Phase 4 Triple therapy
4 Intragastric pH and Bismuth Effect for H. Pylori Eradication Not yet recruiting NCT02894892 Phase 4 (A)Bismuth;(B)Bismuth;(C)Bismuth;(D)Esomeprazole and Bismuth;(E)Esomeprazole and Bismuth;(F)Esomeprazole and Bismuth
5 The Influence of Helicobacter Pylori Eradication on Gastric Pathology: a Long-term, Prospective Cohort Study Not yet recruiting NCT02933229 Phase 4 H. pylori eradication
6 Clarithromycin, Amoxicillin, and Metronidazole Based Regimens to Treat Helicobacter Pylori Infections in Colombia Completed NCT00719420 Phase 3 Clarithromycin, Metronidazole, Amoxicillin (+Omeprazole);Clarithromycin, Amoxicillin, Omeprazole
7 A Randomized Multi-Intervention Trial to Inhibit Precancerous Gastric Lesions in Lingu, Shandong Province Completed NCT00339768 Phase 3 Amoxicillin/omeprazole
8 Gastric Preparation of Magnetic-controlled Capsule Endoscopy Unknown status NCT02846155 Phase 2 simethicone;simethicone combined with pronase
9 L-cysteine Prevents Stomach Exposure to Carcinogenic Acetaldehyde Completed NCT02524262 Phase 2
10 Efficacy Study of Helicobacter Pylori Eradication in Patients Undergoing Subtotal Gastrectomy for Gastric Cancer Completed NCT01002443 Phase 2 Helicobacter pylori eradication;placebo
11 Curcumin in Preventing Gastric Cancer in Patients With Chronic Atrophic Gastritis or Gastric Intestinal Metaplasia Recruiting NCT02782949 Phase 2 Curcumin
12 Chemoprevention of Gastric Carcinogenesis Recruiting NCT02794428 Phase 2 Eflornithine
13 YF476 and Type I Gastric Carcinoids Active, not recruiting NCT01339169 Phase 2 YF476
14 YF476 and Type I Gastric Carcinoids (Norway) Terminated NCT01444014 Phase 2 YF476
15 Usefulness of Serum Pepsinogen and Gastrin as the Predictive Biomarker of Atrophic Gastritis, Intestinal Metaplasia and Gastric Cancer in Korea Unknown status NCT02184910 pepsinogen and gastrin
16 Value of Additional Corpus Biopsy for Diagnosis of H Pylori in Atrophic Gastritis. Prospective Non-randomized Study Unknown status NCT02675010 Not Applicable
17 Difference of Gastric Microbiota in the Process of Correa's Model. Unknown status NCT02833363
18 HLA-DRB1 and HLA-DQB1 Genotyping for Autoantibody-positive and -Negative Patients With Atrophic Glossitis or Burning Mouth Syndrome Unknown status NCT01931293 Not Applicable
19 Diagnosis of Gastric Precancerous Lesions by a Blood Test GastroPanel in Patients With Increased Gastric Cancer Risk Unknown status NCT02624271 Not Applicable
20 Endofaster Test for Helicobacter Pylori Detection in Patients on Proton Pump Inhibitor Therapy Unknown status NCT02126722
21 Immunologic Factors in Reflux Esophagitis and Barrett’s Esophagus Unknown status NCT00155805
22 Oxidative Stress in Intestinal Metaplasia and Metabolic Syndrome Unknown status NCT02695186
23 Role of Statin on the Gastric Inflammation in Patients at High Risk of Gastric Cancer Unknown status NCT01813994 Not Applicable Arm1: Statin;Arm2: Placebo
24 Chemoprevention of Gastric Cancer by Intervention With Helicobacter Pylori and Cyclooxygenase Pathway Unknown status NCT00498134 Not Applicable Triple therapy for H. pylori infection;Cox-2 inhibitor
25 Detection of Methylated Reprimo in Plasma for Asymptomatic Gastric Cancer Unknown status NCT01774266
26 Grading Atrophic Gastritis by Confocal Laser Endomicroscopy Probe (p-CLE) Completed NCT02351154 Not Applicable
27 Long-term Follow-up Prognosis of Atrophic Gastritis After 3 Years Completed NCT01824953
28 Linked Color Imaging to Differentiate H. Pylori Associated Gastritis and Gastric Atrophy Completed NCT02724280 Not Applicable
29 New Technology to Differentiate Normal Gastric Mucosa From Helicobacter Pylori Associated Gastritis and Gastric Atrophy Completed NCT02597517
30 OLGA Stage is More Appropriate in Predicting Early Gastric Cancer Completed NCT02562976
31 Study of the Chinese Prescription Weiqi Decoction on Chronic Atrophic Gastritis Completed NCT00920712 Not Applicable Weiqi decotion
32 Risk Factors for Gastric Disease in Pediatric Helicobacter Pylori (H. Pylori) Completed NCT00212225
33 A Randomized Study Comparing Autofluorescence Imaging(AFI) Followed by Narrow Band Imaging(NBI) With Videoendoscopy for the Detection of High Risk Lesions of Stomach Completed NCT01132534
34 New Classification of Stomach Using Probe-based Confocal Laser Endomicroscopy Completed NCT01896310
35 Optimal Site for Rapid Urease Test in the Stomach Completed NCT02945137
36 Performances of a Fast Test for the Detection of Helicobacter Pylori Antigens in Child Stool Completed NCT03324763
37 Volatile Markers in Digestive Cancer Completed NCT02332213
38 Effect of H. Pylori Eradication on the Reversibility of Atrophic Gastritis and Intestinal Metaplasia in Korean Patients Recruiting NCT02691637
39 Syndrome Patterns for Chronic Atrophic Gastritis Malignant Transformation Recruiting NCT03314038
40 Gastropanel for Gastric Atrophy and Cancer Risk Assessment Recruiting NCT02114411
41 Gastric Cancer Screening Quality Improvement System Establishment Recruiting NCT02457624
42 OLGA and OLGIM Stage System for Gastric Cancer Recruiting NCT03380052
43 Early Detection and Screening Strategy of Gatric Cancer in Sichuan Province-A Prospective Cohort Study (WCH-GC-SIGES-01) Recruiting NCT03597672
44 Surveillance of Patients With Precancerous Lesions of the Stomach Recruiting NCT03250091
45 Early Detection of Tumors of the Digestive Tract by Confocal Endomicroscopy Recruiting NCT02284802 Not Applicable
46 Clinical Study of Weifuchun Treatment on Precancerous Lesions of Gastric Cancer Active, not recruiting NCT03814629 Early Phase 1 Weifuchun
47 Helicobacter Pylori Eradication to Prevent Gastric Cancer Active, not recruiting NCT01133951 Not Applicable OAC triple therapy;Placebo
48 Volatiles in Breath and Headspace Analysis - Diagnostic Markers Enrolling by invitation NCT03228095
49 Risk Assessment and Syndrome Evolution Models for Chronic Atrophic Gastritis Malignant Transformation Not yet recruiting NCT03261934
50 The Study of Chinese Medicine for the Treatment of Chronic Atrophic Gastritis Not yet recruiting NCT02955134 Not Applicable Talcid®;Chinese medicine prescription;Placebo;Compound Azimtamide Entieric-coated Tablets

Search NIH Clinical Center for Atrophic Gastritis

Cochrane evidence based reviews: gastritis, atrophic

Genetic Tests for Atrophic Gastritis

Anatomical Context for Atrophic Gastritis

MalaCards organs/tissues related to Atrophic Gastritis:

41
Testes, Thyroid, Spleen, Liver, Bone, Lung, Pancreas

Publications for Atrophic Gastritis

Articles related to Atrophic Gastritis:

(show top 50) (show all 750)
# Title Authors Year
1
Gastric Neuroendocrine Tumor and Duodenal Gastrinoma With Chronic Autoimmune Atrophic Gastritis. ( 30531243 )
2019
2
Impact of SNP-SNP interactions of DNA repair gene<i>ERCC5</i>and metabolic gene<i>GSTP1</i>on gastric cancer/atrophic gastritis risk in a Chinese population. ( 29434449 )
2018
3
Low PG I/II ratio as a marker of atrophic gastritis: Association with nutritional and metabolic status in healthy people. ( 29768385 )
2018
4
Psychological distress in patients with chronic atrophic gastritis: the risk factors, protection factors, and cumulative effect. ( 29353492 )
2018
5
Polymorphism rs7521584 in miRa89429 is associated with the severity of atrophic gastritis in patients with HelicobacterA pylori infection. ( 29956763 )
2018
6
Multiplex serology of Helicobacter pylori antigens in detection of current infection and atrophic gastritis - A simple and cost-efficient method. ( 29665437 )
2018
7
Material basis research for Huangqi Jianzhong Tang against chronic atrophic gastritis rats through integration of urinary metabonomics and SystemsDock. ( 29777900 )
2018
8
Extranodal Rosai-Dorfman Disease With Mucosal Involvement of the Stomach in a Background of Autoimmune Atrophic Gastritis. ( 29720012 )
2018
9
Accuracy of Endoscopic Diagnosis for Mild Atrophic Gastritis Infected with Helicobacter pylori. ( 29695148 )
2018
10
Correlation between serum vitamin B12 level and peripheral neuropathy in atrophic gastritis. ( 29599609 )
2018
11
Infertility and recurrent miscarriage in a patient with autoimmune atrophic gastritis. ( 29524079 )
2018
12
Identification of N- and O-linked glycans recognized by AAL in saliva of patients with atrophic gastritis and gastric cancer. ( 29865036 )
2018
13
Training Effect on the Inter-observer Agreement in Endoscopic Diagnosis and Grading of Atrophic Gastritis according to Level of Endoscopic Experience. ( 29629520 )
2018
14
Hierarchical and Complex System Entropy Clustering Analysis Based Validation for Traditional Chinese Medicine Syndrome Patterns of Chronic Atrophic Gastritis. ( 29565647 )
2018
15
Helicobacter pylori Eradication Therapy Ameliorates Latent Digestive Symptoms in Chronic Atrophic Gastritis. ( 29587295 )
2018
16
Symptomatic Non-acidic Reflux in a Patient With Chronic Autoimmune Atrophic Gastritis Successfully Treated With Anti-reflux Surgery. ( 29291616 )
2018
17
Unusual association between erythema nodosum and autoimmune atrophic gastritis. ( 29545439 )
2018
18
Treatment of <i>Helicobacter pylori</i> infection in atrophic gastritis. ( 29904244 )
2018
19
Reversibility of atrophic gastritis and intestinal metaplasia after Helicobacter pylori eradication - a prospective study for up to 10 years. ( 29193217 )
2018
20
Occurrence of gastric cancer in patients with atrophic gastritis during long-term follow-up. ( 29911441 )
2018
21
Infection of <i>Helicobacter pylori</i> and Atrophic Gastritis Influence <i>Lactobacillus</i> in Gut Microbiota in a Japanese Population. ( 29681906 )
2018
22
A case of Metaplastic atrophic gastritis in immune Dysregulation, Polyendocrinopathy, Enteropathy, X-linked (IPEX) syndrome. ( 29907148 )
2018
23
Accuracy of Endoscopic Diagnosis of Mild Atrophic Gastritis with Helicobacter pylori Infection. ( 30001615 )
2018
24
Mid- and Deep-Zone Gastritis: A Histologic Pattern Associated With Autoimmune Disease but Distinct From Autoimmune Atrophic Gastritis. ( 30032289 )
2018
25
Exploring the potential pharmacodynamic material basis and pharmacologic mechanism of the Fufang-Xialian-Capsule in chronic atrophic gastritis by network pharmacology approach based on the components absorbed into the blood. ( 30110485 )
2018
26
SNP interactions of PGC with its neighbor lncRNAs enhance the susceptibility to gastric cancer/atrophic gastritis and influence the expression of involved molecules. ( 30155999 )
2018
27
Occurrence and predictors of metaplastic atrophic gastritis in a nation-wide consecutive endoscopic population presenting with upper gastrointestinal symptoms. ( 30161028 )
2018
28
Optical biopsy strategy for the assessment of atrophic gastritis, intestinal metaplasia, and dysplasia. ( 30173255 )
2018
29
Atrophic Gastritis as a Risk Factor for Bone Loss in Premenopausal Women in Their 40s: A Retrospective Cohort Study. ( 30191283 )
2018
30
Association of IL10 gene promoter polymorphisms with risks of gastric cancer and atrophic gastritis. ( 30205739 )
2018
31
Potential role of chromatin remodeling factor genes in atrophic gastritis/gastric cancer risk. ( 30249557 )
2018
32
Risk factors for atrophic gastritis in the Japanese young and middle-aged: a study using double-contrast upper gastrointestinal barium X-ray radiography. ( 30259311 )
2018
33
Difference of Liver and Kidney Metabolic Profiling in Chronic Atrophic Gastritis Rats between Acupuncture and Moxibustion Treatment. ( 30310411 )
2018
34
Grading of Atrophic Gastritis is Useful for Risk Stratification in Endoscopic Screening for Gastric Cancer. ( 30315306 )
2018
35
Chronic Atrophic Gastritis: A Review. ( 30317974 )
2018
36
Hyperplastic polyps arising in autoimmune metaplastic atrophic gastritis patients: is this a distinct clinicopathological entity? ( 30353753 )
2018
37
Confirming the Effects of Qinghuayin against Chronic Atrophic Gastritis and a Preliminary Observation of the Involved Inflammatory Signaling Pathways: An In Vivo Study. ( 30356431 )
2018
38
Nuclear magnetic resonance-based metabolomics approach to evaluate preventive and therapeutic effects of Gastrodia elata Blume on chronic atrophic gastritis. ( 30391812 )
2018
39
Relevance of vitamin D deficiency in patients with chronic autoimmune atrophic gastritis: a prospective study. ( 30409113 )
2018
40
Two Cases of White Globe Appearance in Autoimmune Atrophic Gastritis. ( 30510814 )
2018
41
NMR-based metabolomics Reveals Alterations of Electro-acupuncture Stimulations on Chronic Atrophic Gastritis Rats. ( 28358020 )
2017
42
Helicobacter pylori infection, atrophic gastritis, and pancreatic cancer risk: A meta-analysis of prospective epidemiologic studies. ( 28816977 )
2017
43
Editorial: the non-invasive diagnosis of atrophic gastritis. ( 29105139 )
2017
44
Autoimmune atrophic gastritis: current perspectives. ( 28223833 )
2017
45
An Atypical Presentation of Chronic Atrophic Gastritis: Hemolytic Anemia and Mesenteric Panniculitis. ( 28758037 )
2017
46
Epistatic SNP interaction of ERCC6 with ERCC8 and their joint protein expression contribute to gastric cancer/atrophic gastritis risk. ( 28562347 )
2017
47
The potential value of serum pepsinogen for the diagnosis of atrophic gastritis among the health check-up populations in China: a diagnostic clinical research. ( 28728545 )
2017
48
Severe upper gastrointestinal bleeding determined by a gastric lymphoma associated with Helicobacter pylori-positive atrophic gastritis. ( 28730251 )
2017
49
Long non-coding RNA polymorphisms in 6p21.1 are associated with atrophic gastritis risk and gastric cancer prognosis. ( 29221129 )
2017
50
Systematic review with meta-analysis: diagnostic performance of the combination of pepsinogen, gastrin-17 and anti-Helicobacter pylori antibodies serum assays for the diagnosis of atrophic gastritis. ( 28782119 )
2017

Variations for Atrophic Gastritis

Expression for Atrophic Gastritis

Search GEO for disease gene expression data for Atrophic Gastritis.

Pathways for Atrophic Gastritis

Pathways related to Atrophic Gastritis according to GeneCards Suite gene sharing:

(show all 24)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.13 CXCL8 IL1B TNF TP53
2
Show member pathways
12.13 CXCL8 IL1B S100A8 TNF
3
Show member pathways
12.11 CXCL8 IL1B TNF TP53
4 11.91 CXCL8 TNF TP53
5
Show member pathways
11.91 CXCL8 IL1B IL1RN TNF
6
Show member pathways
11.88 CHGA IL1B TNF
7 11.79 CXCL8 IL1B TP53
8 11.75 CXCL8 IL1B TNF
9 11.73 CXCL8 IL1B TNF
10 11.71 CXCL8 IL1B TNF
11 11.68 CXCL8 IL1B TNF
12 11.64 CXCL8 IL1B TNF TP53
13 11.58 CXCL8 IL1B TNF
14 11.57 CXCL8 IL1B IL1RN SST TNF
15 11.54 IL1B IL1RN TNF
16 11.51 CXCL8 IL1B TNF TP53
17 11.45 CXCL8 IL1B TNF
18
Show member pathways
11.43 CXCL8 IL1B TNF
19 11.35 CXCL8 IL1B TNF
20 11.27 CXCL8 IL1B TNF
21 11.15 CDX2 IL1B TNF
22 10.89 CXCL8 TNF
23 10.8 IL1B TNF
24 10.61 CXCL8 IL1B IL1RN TNF

GO Terms for Atrophic Gastritis

Cellular components related to Atrophic Gastritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.65 CHGA CXCL8 GAST GHRL IL1B IL1RN
2 extracellular region GO:0005576 9.44 ADH7 CHGA CXCL8 GAST GHRL IL1B
3 multivesicular body lumen GO:0097486 9.16 PGA3 PGA5

Biological processes related to Atrophic Gastritis according to GeneCards Suite gene sharing:

(show all 27)
# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.83 CXCL8 IL1B IL1RN S100A8 TNF
2 activation of MAPK activity GO:0000187 9.8 GHRL IL1B TNF
3 response to ethanol GO:0045471 9.78 ADH7 IL1B S100A8
4 cellular response to lipopolysaccharide GO:0071222 9.78 CXCL8 IL1B IL1RN TNF
5 positive regulation of JNK cascade GO:0046330 9.76 IL1B IL1RN TNF
6 response to glucocorticoid GO:0051384 9.74 IL1B IL1RN TNF
7 cytokine-mediated signaling pathway GO:0019221 9.72 CXCL8 IL1B IL1RN TNF TP53
8 positive regulation of interleukin-6 production GO:0032755 9.71 IL1B IL1RN TNF
9 regulation of signaling receptor activity GO:0010469 9.7 CXCL8 GAST GHRL IL1B IL1RN SST
10 protein catabolic process GO:0030163 9.67 PGA3 PGA5 PGC
11 embryonic digestive tract development GO:0048566 9.63 CXCL8 TNF
12 negative regulation of lipid catabolic process GO:0050995 9.62 IL1B TNF
13 positive regulation of glial cell proliferation GO:0060252 9.62 IL1B TNF
14 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.61 IL1B TNF
15 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.6 IL1B TNF
16 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.59 IL1B TNF
17 positive regulation of chemokine biosynthetic process GO:0045080 9.58 IL1B TNF
18 positive regulation of JUN kinase activity GO:0043507 9.58 IL1B IL1RN TNF
19 negative regulation of glutamate secretion GO:0014050 9.56 IL1B IL1RN
20 neutrophil chemotaxis GO:0030593 9.56 CXCL8 IL1B IL1RN S100A8
21 regulation of establishment of endothelial barrier GO:1903140 9.55 IL1B TNF
22 positive regulation of neuroinflammatory response GO:0150078 9.52 IL1B TNF
23 positive regulation of fever generation GO:0031622 9.51 IL1B TNF
24 sequestering of triglyceride GO:0030730 9.46 IL1B TNF
25 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.37 IL1B TNF
26 digestion GO:0007586 9.26 PGA3 PGA5 PGC SST
27 chronic inflammatory response to antigenic stimulus GO:0002439 8.8 IL1B IL1RN TNF

Molecular functions related to Atrophic Gastritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.43 GAST GHRL SST
2 cytokine activity GO:0005125 9.26 CXCL8 IL1B IL1RN TNF
3 interleukin-1 receptor binding GO:0005149 9.16 IL1B IL1RN
4 aspartic-type endopeptidase activity GO:0004190 8.8 PGA3 PGA5 PGC

Sources for Atrophic Gastritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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