MCID: ATR009
MIFTS: 19

Atrophy of Testis

Categories: Endocrine diseases, Reproductive diseases

Aliases & Classifications for Atrophy of Testis

MalaCards integrated aliases for Atrophy of Testis:

Name: Atrophy of Testis 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:11994
ICD9CM 36 608.3
NCIt 51 C123259
SNOMED-CT 69 17585008
ICD10 34 N50.0
UMLS 74 C0156312

Summaries for Atrophy of Testis

MalaCards based summary : Atrophy of Testis is related to pelvic varices. An important gene associated with Atrophy of Testis is DBT (Dihydrolipoamide Branched Chain Transacylase E2), and among its related pathways/superpathways is Striated Muscle Contraction. The drugs Anesthetics and Fibrin Tissue Adhesive have been mentioned in the context of this disorder. Affiliated tissues include testis.

Related Diseases for Atrophy of Testis

Diseases related to Atrophy of Testis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 pelvic varices 9.5 CSN1S1 GNRH1

Symptoms & Phenotypes for Atrophy of Testis

Drugs & Therapeutics for Atrophy of Testis

Drugs for Atrophy of Testis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Anesthetics Not Applicable
2 Fibrin Tissue Adhesive Not Applicable
3 Hemostatics Not Applicable
4 Coagulants Not Applicable
5 Anti-Inflammatory Agents Not Applicable
6 Analgesics Not Applicable

Interventional clinical trials:

(show all 17)
# Name Status NCT ID Phase Drugs
1 Laparoscopic Inguinal Hernia Repair in Infancy and Childhood Unknown status NCT02239185 Phase 3
2 A Comparative Study on Trans-umbilical Single-port Laparoscopic Extra-peritoneal Approach Versus Conventional Repair for Inguinal Hernia in Children Unknown status NCT02960529
3 A Prospective Study Comparing Telescopic vs. Balloon Dissection in Single Incision Laparoscopic Inguinal Herniorraphy (SILTELESCOPIC) Unknown status NCT01883115
4 SIL-TEP vs TEP for Inguinal Hernia Repair in Day Surgery Unknown status NCT02415543 Not Applicable
5 Assessing the Rates of Major Complications in Combined Mini-incision Microscopic Varicocelectomy Completed NCT02092311 Not Applicable
6 Trial of Laparoscopic Compared to Open Inguinal Hernia Repair in Children Younger Than 3 Years Completed NCT00716768 Not Applicable
7 A Novel Technique of Circumcision Incision Orchidopexy Completed NCT02249637
8 A Prospective Study Comparing Single and Multiport Laparoscopic Inguinal Hernia Repair Completed NCT01660048 Not Applicable
9 Study Comparing Total Extraperitoneal Patch "TEP" Versus Lichtenstein According Chronic Pain Completed NCT00803985 Not Applicable
10 One Stage vs. Two Stage Gubernaculum Sparing Laparoscopic Orchidopexy (GSLO) Recruiting NCT02936024 Not Applicable
11 Male Fertility Preservation Using Cryopreservation of Testicular Tissue Before Highly Gonadotoxic Cancer Treatment Recruiting NCT03180918 Not Applicable
12 Comparison of Self Fixating Mesh to Mesh Fixation With Metallic Tacks in Laparoscopic Inguinal Hernia Repair Recruiting NCT03564535 Not Applicable
13 The Effect and Prognosis of Different Operations on Varicocele - a Single-center Clinical Study Active, not recruiting NCT01757548 Not Applicable
14 Expertise-Based Randomized Controlled Trial of Scrotal Versus Inguinal Orchidopexy on Post-operative Pain Active, not recruiting NCT02158780 Not Applicable
15 Comparison of Recurrence Rate of 2 Herniotomy Techniques in Children Older Than 2 Years Enrolling by invitation NCT03392636 Not Applicable
16 Varicocele Treatement by Endovasculer Embolization Not yet recruiting NCT03341897 Not Applicable
17 Hernia Exploration oR Not In Infants Analysis Not yet recruiting NCT03623893 Not Applicable

Search NIH Clinical Center for Atrophy of Testis

Genetic Tests for Atrophy of Testis

Anatomical Context for Atrophy of Testis

MalaCards organs/tissues related to Atrophy of Testis:

42
Testis

Publications for Atrophy of Testis

Variations for Atrophy of Testis

Expression for Atrophy of Testis

Search GEO for disease gene expression data for Atrophy of Testis.

Pathways for Atrophy of Testis

Pathways related to Atrophy of Testis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.48 TNNI1 TNNI2

GO Terms for Atrophy of Testis

Cellular components related to Atrophy of Testis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 troponin complex GO:0005861 8.62 TNNI1 TNNI2

Biological processes related to Atrophy of Testis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 aging GO:0007568 9.37 GNRH1 NQO1
2 response to organic cyclic compound GO:0014070 9.32 GNRH1 NQO1
3 response to ethanol GO:0045471 9.26 GNRH1 NQO1
4 muscle contraction GO:0006936 9.16 TNNI1 TNNI2
5 response to estradiol GO:0032355 8.96 CSN1S1 NQO1
6 muscle filament sliding GO:0030049 8.62 TNNI1 TNNI2

Sources for Atrophy of Testis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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