MCID: ATR009
MIFTS: 22

Atrophy of Testis

Categories: Endocrine diseases, Reproductive diseases

Aliases & Classifications for Atrophy of Testis

MalaCards integrated aliases for Atrophy of Testis:

Name: Atrophy of Testis 12 15 32

Classifications:



External Ids:

Disease Ontology 12 DOID:11994
ICD9CM 34 608.3
NCIt 50 C123259
SNOMED-CT 67 155938008
ICD10 32 N50.0
UMLS 70 C0156312

Summaries for Atrophy of Testis

MalaCards based summary : Atrophy of Testis is related to cerebellar ataxia, deafness, and narcolepsy, autosomal dominant and endometrial stromal tumor. An important gene associated with Atrophy of Testis is H2AC18 (H2A Clustered Histone 18), and among its related pathways/superpathways are Chromatin organization and Striated Muscle Contraction. Affiliated tissues include testis and testes.

Related Diseases for Atrophy of Testis

Graphical network of the top 20 diseases related to Atrophy of Testis:



Diseases related to Atrophy of Testis

Symptoms & Phenotypes for Atrophy of Testis

Drugs & Therapeutics for Atrophy of Testis

Search Clinical Trials , NIH Clinical Center for Atrophy of Testis

Genetic Tests for Atrophy of Testis

Anatomical Context for Atrophy of Testis

MalaCards organs/tissues related to Atrophy of Testis:

40
Testis, Testes

Publications for Atrophy of Testis

Articles related to Atrophy of Testis:

(show all 16)
# Title Authors PMID Year
1
Modified Inguinal Microscope-Assisted Varicocelectomy under Local Anesthesia: A Non-randomised Controlled Study of 3565 Cases. 61
29434272 2018
2
Combination of liechtenstein repair with herniorrhaphy in open inguinal hernia repair- a prospective observational single center study. 61
25478390 2014
3
Testicular rerouting by modified Prentiss maneuver: usefulness in bilateral synchronous orchidopexy for high inguinal undescended testes. 61
25092097 2014
4
Effect of tertiary-butyl hydroperoxide (TBHP)-induced oxidative stress on mice sperm quality and testis histopathology. 61
22803951 2013
5
[Transumbilical laparoscopic operation for the incarcerated oblique inguinal hernia in the infants]. 61
15938928 2005
6
Effect of artemether on Schistosoma mansoni: dose-efficacy relationship, and changes in worm morphology and histopathology. 61
15597709 2004
7
[Transition of soleus troponin I isoforms and atrophy of testis in tail-suspended rats]. 61
11892734 2001
8
Ultrastructural changes in testis of gobiid fish Glossogobius giuris (Ham) induced by fenthion. 61
11480215 2001
9
Management of undescended testis. 61
10932966 2000
10
NTP Toxicology and Carcinogenesis Studies of Acetaminophen (CAS No. 103-90-2) in F344 Rats and B6C3F1 Mice (Feed Studies). 61
12637965 1993
11
Effect of hydrocele on testis and spermatogenesis. 61
2253014 1990
12
Studies on the pathology of experimental zinc deficiency in guinea-pigs. 61
3417909 1988
13
Psychological and physical long-term effects of torture. A follow-up examination of 22 Greek persons exposed to torture 1967-1974. 61
4023668 1985
14
Altered structural and functional integrity of the reproductive tissues in estradiol benzoate-treated intact male albino rats. 61
6148324 1984
15
AROMATIC-INDUCED PREVENTION OF FETAL TOXICITY OF 7,12-DIMETHYLBENZ(ALPHA)ANTHRACENE. 61
14176292 1964
16
SELECTIVE DESTRUCTION IN TESTIS INDUCED BY 7,12-DIMETHYLBENZ [a] ANTHRACENE. 61
19867232 1963

Variations for Atrophy of Testis

Expression for Atrophy of Testis

Search GEO for disease gene expression data for Atrophy of Testis.

Pathways for Atrophy of Testis

Pathways related to Atrophy of Testis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.87 MEAF6 JADE1 ING5 H2AC18 DMAP1
2 11.01 TNNI2 TNNI1
3
Show member pathways
10.61 MEAF6 ING5

GO Terms for Atrophy of Testis

Cellular components related to Atrophy of Testis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chromosome GO:0005694 9.56 MEAF6 JADE1 ING5 H2AC18
2 NuA4 histone acetyltransferase complex GO:0035267 9.32 MEAF6 DMAP1
3 MOZ/MORF histone acetyltransferase complex GO:0070776 9.16 MEAF6 ING5
4 troponin complex GO:0005861 8.96 TNNI2 TNNI1
5 histone acetyltransferase complex GO:0000123 8.8 MEAF6 JADE1 ING5

Biological processes related to Atrophy of Testis according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 chromatin organization GO:0006325 9.7 MEAF6 ING5 DMAP1
2 muscle contraction GO:0006936 9.54 TNNI2 TNNI1
3 histone acetylation GO:0016573 9.51 MEAF6 ING5
4 cardiac muscle contraction GO:0060048 9.49 TNNI2 TNNI1
5 histone H3 acetylation GO:0043966 9.48 JADE1 ING5
6 muscle filament sliding GO:0030049 9.46 TNNI2 TNNI1
7 histone H4 acetylation GO:0043967 9.43 ING5 DMAP1
8 skeletal muscle contraction GO:0003009 9.4 TNNI2 TNNI1
9 histone H4-K16 acetylation GO:0043984 9.37 MEAF6 JADE1
10 histone H4-K8 acetylation GO:0043982 9.32 MEAF6 JADE1
11 histone H4-K5 acetylation GO:0043981 9.26 MEAF6 JADE1
12 histone H2A acetylation GO:0043968 9.16 MEAF6 DMAP1
13 histone H3-K14 acetylation GO:0044154 8.96 MEAF6 ING5
14 histone H4-K12 acetylation GO:0043983 8.62 MEAF6 JADE1

Sources for Atrophy of Testis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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