MCID: ATY007
MIFTS: 18

Atypical Follicular Adenoma

Categories: Cancer diseases, Endocrine diseases

Aliases & Classifications for Atypical Follicular Adenoma

MalaCards integrated aliases for Atypical Follicular Adenoma:

Name: Atypical Follicular Adenoma 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:8292
NCIt 49 C27729
UMLS 71 C1266046

Summaries for Atypical Follicular Adenoma

MalaCards based summary : Atypical Follicular Adenoma is related to follicular adenoma and struma ovarii. An important gene associated with Atypical Follicular Adenoma is CNOT3 (CCR4-NOT Transcription Complex Subunit 3), and among its related pathways/superpathways is Pathways in cancer. Affiliated tissues include thyroid, and related phenotypes are growth/size/body region and digestive/alimentary

Related Diseases for Atypical Follicular Adenoma

Diseases related to Atypical Follicular Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 39)
# Related Disease Score Top Affiliating Genes
1 follicular adenoma 29.5 TG RET PAX8
2 struma ovarii 10.1 TG RET
3 athyreosis 10.0 TG PAX8
4 multicentric papillary thyroid carcinoma 10.0 TG RET
5 thyroid carcinoma 10.0 TG RET
6 nasal cavity olfactory neuroblastoma 10.0 TG PAX8
7 malignant struma ovarii 10.0 TG RET
8 hypothyroidism, congenital, nongoitrous, 2 10.0 TG PAX8
9 tall cell variant papillary carcinoma 10.0 TG RET
10 ovarian germ cell teratoma 10.0 TG RET
11 toxic diffuse goiter 10.0 TG C6orf15
12 nodular goiter 10.0 TG RET
13 parathyroid gland disease 10.0 TG RET
14 thyroid cancer, nonmedullary, 2 10.0 TG PAX8
15 autoimmune disease of endocrine system 9.9 TG RET
16 multinodular goiter 9.9 TG PAX8
17 adenoma 9.9
18 renal hypodysplasia/aplasia 1 9.9 RET PAX8
19 thyroid carcinoma, familial medullary 9.9 TG RET
20 pendred syndrome 9.9 TG PAX8
21 thyroiditis 9.9 TG RET
22 benign struma ovarii 9.8 TG RET PAX8
23 endocrine organ benign neoplasm 9.7 TG RET
24 thyroid gland anaplastic carcinoma 9.7 TG RET PAX8
25 thyroid gland medullary carcinoma 9.7 TG RET PAX8
26 thyroid gland follicular carcinoma 9.7 TG RET PAX8
27 differentiated thyroid carcinoma 9.7 TG RET PAX8
28 thyroid gland papillary carcinoma 9.7 TG RET PAX8
29 papillary carcinoma 9.7 TG RET PAX8
30 goiter 9.7 TG RET PAX8
31 parathyroid carcinoma 9.7 TERT RET
32 thyroid gland disease 9.7 TG RET PAX8
33 paraganglioma 9.7 TG RET
34 hypothyroidism 9.7 TG RET PAX8
35 mucoepidermoid carcinoma 9.6 TG PAX8
36 thyroid angiosarcoma 9.5 TG TERT PAX8
37 nonencapsulated sclerosing carcinoma 9.4 TG TERT RET
38 thyroid tumor 9.4 TG TERT RET
39 thyroid gland cancer 8.7 TG TERT RET PAX8 C6orf15

Graphical network of the top 20 diseases related to Atypical Follicular Adenoma:



Diseases related to Atypical Follicular Adenoma

Symptoms & Phenotypes for Atypical Follicular Adenoma

MGI Mouse Phenotypes related to Atypical Follicular Adenoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.5 C6orf15 CNOT3 ITGB3 PAX8 RET TERT
2 digestive/alimentary MP:0005381 9.46 ITGB3 RET TERT TG
3 skeleton MP:0005390 9.02 CNOT3 ITGB3 PAX8 TERT TG

Drugs & Therapeutics for Atypical Follicular Adenoma

Search Clinical Trials , NIH Clinical Center for Atypical Follicular Adenoma

Genetic Tests for Atypical Follicular Adenoma

Anatomical Context for Atypical Follicular Adenoma

MalaCards organs/tissues related to Atypical Follicular Adenoma:

40
Thyroid

Publications for Atypical Follicular Adenoma

Articles related to Atypical Follicular Adenoma:

# Title Authors PMID Year
1
Improving Access to Image-guided Procedures at an Integrated Rural Critical Access Hospital: Ultrasound-guided Thyroid Biopsy Program. 61
28410848 2017
2
Is atypical follicular adenoma of the thyroid a preinvasive malignancy? 61
12874762 2003
3
Thyroid paraganglioma: a clinicopathologic and immunohistochemical study of three cases. 61
9236830 1997
4
Alterations of p53 and expression of WAF1/p21 in human thyroid tumors. 61
8777377 1996
5
[Aspiration biopsy cytology of the thyroid gland: results and critical evaluation (author's transl)]. 61
516745 1979

Variations for Atypical Follicular Adenoma

Expression for Atypical Follicular Adenoma

Search GEO for disease gene expression data for Atypical Follicular Adenoma.

Pathways for Atypical Follicular Adenoma

Pathways related to Atypical Follicular Adenoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.52 TERT RET PAX8

GO Terms for Atypical Follicular Adenoma

Biological processes related to Atypical Follicular Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 thyroid gland development GO:0030878 8.62 TG PAX8

Sources for Atypical Follicular Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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