MCID: ATY007
MIFTS: 24

Atypical Follicular Adenoma

Categories: Cancer diseases, Endocrine diseases

Aliases & Classifications for Atypical Follicular Adenoma

MalaCards integrated aliases for Atypical Follicular Adenoma:

Name: Atypical Follicular Adenoma 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:8292
NCIt 50 C27729
SNOMED-CT 68 128892009
UMLS 73 C1266046

Summaries for Atypical Follicular Adenoma

MalaCards based summary : Atypical Follicular Adenoma is related to esophageal neuroendocrine tumor and ovarian large-cell neuroendocrine carcinoma. An important gene associated with Atypical Follicular Adenoma is CHGA (Chromogranin A), and among its related pathways/superpathways are Integrated Cancer Pathway and DNA damage_ATM/ATR regulation of G1/S checkpoint. Affiliated tissues include thyroid.

Related Diseases for Atypical Follicular Adenoma

Diseases related to Atypical Follicular Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 231)
# Related Disease Score Top Affiliating Genes
1 esophageal neuroendocrine tumor 10.7 CHGA SYP
2 ovarian large-cell neuroendocrine carcinoma 10.7 CHGA SYP
3 adenoma of the pancreas 10.7 CHGA SYP
4 acinar cell cystadenocarcinoma 10.7 CHGA SYP
5 peritoneal serous adenocarcinoma 10.7 CHGA SYP
6 primary hepatic neuroendocrine carcinoma 10.7 CHGA SYP
7 chordoid meningioma 10.7 CHGA SYP
8 conventional angiosarcoma 10.7 CHGA SYP
9 intracranial primitive neuroectodermal tumor 10.6 CHGA ENO2
10 pulmonary sclerosing hemangioma 10.6 CHGA SYP
11 pancreatoblastoma 10.6 CHGA SYP
12 ureter, cancer of 10.6 CHGA SYP
13 tanycytic ependymoma 10.6 CHGA SYP
14 epithelioid malignant peripheral nerve sheath tumor 10.6 CHGA ENO2
15 non-functioning pancreatic endocrine tumor 10.6 CHGA SYP
16 goblet cell carcinoid 10.6 CHGA ENO2
17 retroperitoneal neuroblastoma 10.6 CDKN1A ENO2
18 binswanger's disease 10.6 CHGA SYP
19 female urethral cancer 10.6 CEACAM5 CHGA
20 malignant sertoli cell tumor 10.6 ENO2 SYP
21 sinonasal undifferentiated carcinoma 10.6 ENO2 SYP
22 sensory organ benign neoplasm 10.5 ENO2 SYP
23 cutaneous ganglioneuroma 10.5 ENO2 SYP
24 extrahepatic bile duct adenocarcinoma 10.5 ENO2 SYP
25 gastric tubular adenocarcinoma 10.5 CHGA SYP
26 duodenal gastrinoma 10.5 CHGA ENO2
27 papillary tumor of the pineal region 10.5 ENO2 SYP
28 orbital cancer 10.5 ENO2 SYP
29 middle ear adenoma 10.5 ENO2 SYP
30 ovarian carcinosarcoma 10.5 ENO2 SYP
31 breast papillary carcinoma 10.5 CHGA SYP
32 subependymal glioma 10.5 ENO2 SYP
33 extraosseous chondrosarcoma 10.5 ENO2 SYP
34 benign ependymoma 10.5 ENO2 SYP
35 astroblastoma 10.5 ENO2 SYP
36 pineal gland cancer 10.5 ENO2 SYP
37 liver sarcoma 10.5 CEACAM5 CHGA
38 endometrial small cell carcinoma 10.5 ENO2 SYP
39 melanotic neuroectodermal tumor 10.5 ENO2 SYP
40 angiomyoma 10.5 ENO2 SYP
41 desmoplastic small round cell tumor 10.5 ENO2 SYP
42 urethral benign neoplasm 10.5 CEACAM5 CHGA
43 bone benign neoplasm 10.5 ENO2 SYP
44 mucinous adenofibroma 10.5 CEACAM5 SYP
45 extraskeletal ewing sarcoma 10.5 ENO2 SYP
46 water-clear cell adenoma 10.5 SYP TG
47 connective tissue benign neoplasm 10.5 ENO2 SYP
48 cystadenoma 10.5 CHGA SYP
49 intraocular retinoblastoma 10.5 ENO2 SYP
50 subependymal giant cell astrocytoma 10.5 ENO2 SYP

Graphical network of the top 20 diseases related to Atypical Follicular Adenoma:



Diseases related to Atypical Follicular Adenoma

Symptoms & Phenotypes for Atypical Follicular Adenoma

Drugs & Therapeutics for Atypical Follicular Adenoma

Search Clinical Trials , NIH Clinical Center for Atypical Follicular Adenoma

Genetic Tests for Atypical Follicular Adenoma

Anatomical Context for Atypical Follicular Adenoma

MalaCards organs/tissues related to Atypical Follicular Adenoma:

41
Thyroid

Publications for Atypical Follicular Adenoma

Articles related to Atypical Follicular Adenoma:

# Title Authors Year
1
Is atypical follicular adenoma of the thyroid a preinvasive malignancy? ( 12874762 )
2003

Variations for Atypical Follicular Adenoma

Expression for Atypical Follicular Adenoma

Search GEO for disease gene expression data for Atypical Follicular Adenoma.

Pathways for Atypical Follicular Adenoma

GO Terms for Atypical Follicular Adenoma

Biological processes related to Atypical Follicular Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular response to ionizing radiation GO:0071479 9.48 CDKN1A TP53
2 intrinsic apoptotic signaling pathway GO:0097193 9.46 CDKN1A TP53
3 positive regulation of reactive oxygen species metabolic process GO:2000379 9.43 CDKN1A TP53
4 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator GO:0042771 9.4 CDKN1A TP53
5 cellular response to gamma radiation GO:0071480 9.37 CDKN1A TP53
6 response to X-ray GO:0010165 9.32 CDKN1A TP53
7 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 9.26 CDKN1A TP53
8 replicative senescence GO:0090399 9.16 CDKN1A TP53
9 positive regulation of cAMP metabolic process GO:0030816 8.96 CALCA CHGA
10 signal transduction by p53 class mediator GO:0072331 8.62 CDKN1A TP53

Sources for Atypical Follicular Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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