MCID: ATY007
MIFTS: 23

Atypical Follicular Adenoma

Categories: Cancer diseases, Endocrine diseases

Aliases & Classifications for Atypical Follicular Adenoma

MalaCards integrated aliases for Atypical Follicular Adenoma:

Name: Atypical Follicular Adenoma 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:8292
NCIt 51 C27729
UMLS 74 C1266046

Summaries for Atypical Follicular Adenoma

MalaCards based summary : Atypical Follicular Adenoma is related to primary pigmented nodular adrenocortical disease and tubular adenocarcinoma. An important gene associated with Atypical Follicular Adenoma is CHGA (Chromogranin A), and among its related pathways/superpathways are miRNAs involved in DNA damage response and Integrated Cancer Pathway. Affiliated tissues include thyroid.

Related Diseases for Atypical Follicular Adenoma

Diseases related to Atypical Follicular Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 232)
# Related Disease Score Top Affiliating Genes
1 primary pigmented nodular adrenocortical disease 10.4 CHGA SYP
2 tubular adenocarcinoma 10.4 CHGA SYP
3 sclerosing hemangioma 10.4 CHGA SYP
4 tanycytic ependymoma 10.4 CHGA SYP
5 pulmonary sclerosing hemangioma 10.4 CHGA SYP
6 gastric tubular adenocarcinoma 10.4 CHGA SYP
7 pancreatoblastoma 10.4 CHGA SYP
8 non-functioning pancreatic endocrine tumor 10.4 CHGA SYP
9 binswanger's disease 10.4 CHGA SYP
10 cystadenoma 10.3 CHGA SYP
11 ureter small cell carcinoma 10.3 CHGA SYP
12 duodenal gastrinoma 10.3 CHGA ENO2
13 chondrosarcoma, extraskeletal myxoid 10.3 ENO2 SYP
14 bone benign neoplasm 10.3 ENO2 SYP
15 connective tissue benign neoplasm 10.3 ENO2 SYP
16 adrenal rest tumor 10.3 ENO2 SYP
17 esophageal neuroendocrine tumor 10.3 CHGA SYP
18 angiomyoma 10.3 ENO2 SYP
19 intraocular retinoblastoma 10.3 ENO2 SYP
20 pineal parenchymal tumor of intermediate differentiation 10.3 ENO2 SYP
21 subependymal giant cell astrocytoma 10.3 ENO2 SYP
22 cervical clear cell adenocarcinoma 10.3 ENO2 SYP
23 ovarian large-cell neuroendocrine carcinoma 10.3 CHGA SYP
24 desmoplastic small round cell tumor 10.3 ENO2 SYP
25 extraskeletal ewing sarcoma 10.3 ENO2 SYP
26 ganglioneuroblastoma 10.3 ENO2 SYP
27 acinar cell cystadenocarcinoma 10.3 CHGA SYP
28 pancreatic cystadenoma 10.3 CEACAM5 CHGA
29 peritoneal serous adenocarcinoma 10.3 CHGA SYP
30 spermatocele 10.3 SYP TG
31 primary hepatic neuroendocrine carcinoma 10.3 CHGA SYP
32 ovarian mucinous neoplasm 10.3 CEACAM5 SYP
33 intracranial primitive neuroectodermal tumor 10.3 CHGA ENO2
34 carotid body cancer 10.2 ENO2 SYP
35 malignant sertoli cell tumor 10.2 ENO2 SYP
36 islet cell tumor 10.2 CALCA CHGA
37 tracheal cancer 10.2 CEACAM5 ENO2
38 female urethral cancer 10.2 CEACAM5 CHGA
39 breast adenomyoepithelioma 10.2 CEACAM5 ENO2
40 breast myoepithelial neoplasm 10.2 CEACAM5 ENO2
41 chordoid meningioma 10.2 CHGA SYP
42 chondroid chordoma 10.2 CEACAM5 ENO2
43 sinonasal undifferentiated carcinoma 10.2 ENO2 SYP
44 rete testis neoplasm 10.2 CEACAM5 ENO2
45 congenital epulis 10.2 CEACAM5 ENO2
46 cutaneous ganglioneuroma 10.2 ENO2 SYP
47 extrahepatic bile duct adenocarcinoma 10.2 ENO2 SYP
48 papillary tumor of the pineal region 10.2 ENO2 SYP
49 sensory organ benign neoplasm 10.2 ENO2 SYP
50 mucinous adenofibroma 10.2 CEACAM5 SYP

Graphical network of the top 20 diseases related to Atypical Follicular Adenoma:



Diseases related to Atypical Follicular Adenoma

Symptoms & Phenotypes for Atypical Follicular Adenoma

Drugs & Therapeutics for Atypical Follicular Adenoma

Search Clinical Trials , NIH Clinical Center for Atypical Follicular Adenoma

Genetic Tests for Atypical Follicular Adenoma

Anatomical Context for Atypical Follicular Adenoma

MalaCards organs/tissues related to Atypical Follicular Adenoma:

42
Thyroid

Publications for Atypical Follicular Adenoma

Articles related to Atypical Follicular Adenoma:

# Title Authors Year
1
Is atypical follicular adenoma of the thyroid a preinvasive malignancy? ( 12874762 )
2003

Variations for Atypical Follicular Adenoma

Expression for Atypical Follicular Adenoma

Search GEO for disease gene expression data for Atypical Follicular Adenoma.

Pathways for Atypical Follicular Adenoma

Pathways related to Atypical Follicular Adenoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.1 CDKN1A TP53
2 11.03 CDKN1A TP53
3 10.97 CDKN1A TP53
4 10.85 CDKN1A TP53
5 10.66 CDKN1A TP53
6
Show member pathways
10.3 CDKN1A TP53
7 9.7 CDKN1A TP53

GO Terms for Atypical Follicular Adenoma

Cellular components related to Atypical Follicular Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 terminal bouton GO:0043195 8.62 CALCA SYP

Biological processes related to Atypical Follicular Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular response to ionizing radiation GO:0071479 9.32 CDKN1A TP53
2 intrinsic apoptotic signaling pathway GO:0097193 9.26 CDKN1A TP53
3 positive regulation of reactive oxygen species metabolic process GO:2000379 9.16 CDKN1A TP53
4 replicative senescence GO:0090399 8.96 CDKN1A TP53
5 signal transduction by p53 class mediator GO:0072331 8.62 CDKN1A TP53

Sources for Atypical Follicular Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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