Atypical Follicular Adenoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Atypical Follicular Adenoma

MalaCards integrated aliases for Atypical Follicular Adenoma:

Name: Atypical Follicular Adenoma ¹² ¹⁵ ⁷¹

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Endocrine diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:8292

NCIt ⁴⁹ C27729

SNOMED-CT ⁶⁷ 128892009

UMLS ⁷¹ C1266046

Sources

Summaries for Atypical Follicular Adenoma

MalaCards based summary : Atypical Follicular Adenoma is related to follicular adenoma and clear cell adenoma. An important gene associated with Atypical Follicular Adenoma is TG (Thyroglobulin), and among its related pathways/superpathways is Neuroscience. Affiliated tissues include thyroid, and related phenotypes are behavior/neurological and growth/size/body region

Sources

Related Diseases for Atypical Follicular Adenoma

Diseases related to Atypical Follicular Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 103)

#	Related Disease	Score	Top Affiliating Genes
1	follicular adenoma	29.0	TG RET PAX8 CALCA
2	clear cell adenoma	10.2	TG PAX8
3	athyreosis	10.2	TG PAX8
4	ovarian benign neoplasm	10.2	TG PAX8
5	multicentric papillary thyroid carcinoma	10.2	TG RET
6	hypothyroidism, congenital, nongoitrous, 2	10.2	TG PAX8
7	benign struma ovarii	10.2	TG RET
8	struma ovarii	10.2	TG RET
9	malignant struma ovarii	10.2	TG RET
10	postsurgical hypothyroidism	10.1	TG RET
11	tall cell variant papillary carcinoma	10.1	TG RET
12	ovarian germ cell teratoma	10.1	TG RET
13	thyroid gland mucoepidermoid carcinoma	10.1	TG CALCA
14	spindle epithelial tumor with thymus-like differentiation tumor	10.1	TG CALCA
15	substernal goiter	10.1	TG CALCA
16	isthmus cancer	10.1	TG CALCA
17	fetal adenoma	10.1	TG CALCA
18	acute thyroiditis	10.1	TG CALCA
19	epithelial malignant thymoma	10.1	TG CALCA
20	dendritic cell thymoma	10.1	TG CALCA
21	ectopic thymus	10.1	TG CALCA
22	thyroid tumor	10.0	TG RET
23	thyroid lymphoma	10.0	TG CALCA
24	papillary thyroid microcarcinoma	10.0	TG CALCA
25	endemic goiter	10.0	TG CALCA
26	nontoxic goiter	10.0	TG CALCA
27	graves disease 1	10.0	TG CALCA
28	pendred syndrome	9.9	TG PAX8
29	mature teratoma	9.9	TG ENO2
30	mature teratoma of the ovary	9.9	TG ENO2
31	multiple endocrine neoplasia, type iib	9.9	RET CALCA
32	multiple endocrine neoplasia	9.9	RET CALCA
33	endometrial small cell carcinoma	9.9	TG ENO2
34	adenoma	9.9
35	vipoma	9.9	NTS CALCA
36	ovarian large-cell neuroendocrine carcinoma	9.9	PAX8 ENO2
37	diabetes insipidus	9.9	TG CALCA
38	renal hypodysplasia/aplasia 1	9.9	RET PAX8
39	differentiated thyroid carcinoma	9.9	TG RET PAX8
40	multiple endocrine neoplasia, type iia	9.9	RET CALCA
41	exophthalmos	9.8	TG ENO2
42	parathyroid carcinoma	9.8	RET CALCA
43	pain agnosia	9.8	NTS CALCA
44	mixed cell type cancer	9.8	PAX8 ENO2
45	agnosia	9.8	NTS CALCA
46	thyroid sarcoma	9.8	TG PAX8 CALCA
47	thyroid angiosarcoma	9.8	TG PAX8 CALCA
48	mucoepidermoid carcinoma	9.8	TG PAX8 CALCA
49	thyroid cancer, nonmedullary, 2	9.8	TG PAX8 CALCA
50	ileus	9.7	NTS CALCA

Graphical network of the top 20 diseases related to Atypical Follicular Adenoma:

Sources

Symptoms & Phenotypes for Atypical Follicular Adenoma

MGI Mouse Phenotypes related to Atypical Follicular Adenoma:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	behavior/neurological	MP:0005386	9.43	CNOT3 ENO2 NTS PAX8 RET TG
2	growth/size/body region	MP:0005378	9.1	CNOT3 ENO2 NTS PAX8 RET TG

Sources

Drugs & Therapeutics for Atypical Follicular Adenoma

Search Clinical Trials , NIH Clinical Center for Atypical Follicular Adenoma

Sources

Genetic Tests for Atypical Follicular Adenoma

Sources

Anatomical Context for Atypical Follicular Adenoma

MalaCards organs/tissues related to Atypical Follicular Adenoma:

⁴⁰

Thyroid

Sources

Publications for Atypical Follicular Adenoma

Articles related to Atypical Follicular Adenoma:

#	Title	Authors	PMID	Year
1	Improving Access to Image-guided Procedures at an Integrated Rural Critical Access Hospital: Ultrasound-guided Thyroid Biopsy Program. ⁶¹	Le TQ...Prabhakar AM	28410848	2017
2	Is atypical follicular adenoma of the thyroid a preinvasive malignancy? ⁶¹	Tzen CY...Fu YS	12874762	2003
3	Thyroid paraganglioma: a clinicopathologic and immunohistochemical study of three cases. ⁶¹	LaGuette J...Rosai J	9236830	1997
4	Alterations of p53 and expression of WAF1/p21 in human thyroid tumors. ⁶¹	Zedenius J...Auer G	8777377	1996
5	[Aspiration biopsy cytology of the thyroid gland: results and critical evaluation (author's transl)]. ⁶¹	Hofstadter F...Unterkircher S	516745	1979

Sources

Genes for Atypical Follicular Adenoma

Genes related to Atypical Follicular Adenoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	TG	Thyroglobulin	Protein Coding	5.79	DISEASES inferred ¹⁵
2	PAX8	Paired Box 8	Protein Coding	5.37	DISEASES inferred ¹⁵
3	CNOT3	CCR4-NOT Transcription Complex Subunit 3	Protein Coding	5.26	DISEASES inferred ¹⁵
4	RET	Ret Proto-Oncogene	Protein Coding	5.25	DISEASES inferred ¹⁵
5	CALCA	Calcitonin Related Polypeptide Alpha	Protein Coding	5.11	DISEASES inferred ¹⁵
6	ENO2	Enolase 2	Protein Coding	4.79	DISEASES inferred ¹⁵
7	NTS	Neurotensin	Protein Coding	4.72	DISEASES inferred ¹⁵

Sources

Variations for Atypical Follicular Adenoma

Sources

Expression for Atypical Follicular Adenoma

Search GEO for disease gene expression data for Atypical Follicular Adenoma.

Sources

Pathways for Atypical Follicular Adenoma

Pathways related to Atypical Follicular Adenoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Neuroscience ⁴	11.33	RET ENO2 CALCA

Sources

GO Terms for Atypical Follicular Adenoma

Cellular components related to Atypical Follicular Adenoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	neuronal cell body	GO:0043025	8.8	RET ENO2 CALCA

Biological processes related to Atypical Follicular Adenoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	thyroid gland development	GO:0030878	8.96	TG PAX8
2	response to pain	GO:0048265	8.62	RET CALCA

Sources

Sources for Atypical Follicular Adenoma

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NIH Rare Diseases

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM

⁵⁷ OMIM via Orphanet

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia