MCID: ATY008
MIFTS: 34

Atypical Lipomatous Tumor

Categories: Cancer diseases

Aliases & Classifications for Atypical Lipomatous Tumor

MalaCards integrated aliases for Atypical Lipomatous Tumor:

Name: Atypical Lipomatous Tumor 12 15
Atypical Lipoma 73

Classifications:



External Ids:

Disease Ontology 12 DOID:5690
NCIt 50 C4250
SNOMED-CT 68 28655007

Summaries for Atypical Lipomatous Tumor

MalaCards based summary : Atypical Lipomatous Tumor, also known as atypical lipoma, is related to well-differentiated liposarcoma and spindle cell lipoma. An important gene associated with Atypical Lipomatous Tumor is MDM2 (MDM2 Proto-Oncogene), and among its related pathways/superpathways are Cellular Senescence (REACTOME) and Glioma. The drugs Rosiglitazone and Maleic acid have been mentioned in the context of this disorder. Affiliated tissues include breast, tongue and skin, and related phenotype is neoplasm.

Wikipedia : 76 Liposarcoma is a cancer that arises in fat cells in deep soft tissue, such as that inside the thigh or... more...

Related Diseases for Atypical Lipomatous Tumor

Diseases related to Atypical Lipomatous Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 82)
# Related Disease Score Top Affiliating Genes
1 well-differentiated liposarcoma 31.9 CDK4 CDKN2A HMGA2 MDM2 TSPAN31
2 spindle cell lipoma 30.3 CDK4 MDM2
3 lipoblastoma 30.3 CDK4 MDM2
4 pleomorphic lipoma 30.3 HMGA2 MDM2
5 pleomorphic liposarcoma 30.0 CDKN2A MDM2
6 dedifferentiated liposarcoma 29.9 CDK4 CDKN2A HMGA2 MDM2
7 liposarcoma 29.8 CDK4 CDKN2A FUS HMGA2 MDM2 TSPAN31
8 spindle cell liposarcoma 29.8 CDK4 MDM2 SMARCB1
9 sarcoma 29.7 CDK4 FUS MDM2
10 ring chromosome 7 10.2 CDK4 MDM2
11 undifferentiated embryonal sarcoma of the liver 10.2 CDK4 MDM2
12 embryonal sarcoma 10.2 CDK4 MDM2
13 inflammatory mfh 10.2 CDK4 MDM2
14 malignant fibrous histiocytoma of bone 10.2 CDK4 MDM2
15 bone osteosarcoma 10.2 CDK4 MDM2
16 leiomyosarcoma 10.2 CDK4 MDM2
17 mesenchymoma 10.1 HMGA2 MDM2
18 periosteal osteogenic sarcoma 10.1 CDK4 MDM2
19 juxtacortical osteosarcoma 10.1 CDK4 MDM2
20 peripheral osteosarcoma 10.1 CDK4 MDM2
21 malignant fibroxanthoma 10.1 CDK4 MDM2
22 retroperitoneal sarcoma 10.1 MDM2 SMARCB1
23 malignant mesenchymoma 10.1 CDK4 MDM2
24 cornea cancer 10.1 CDK4 CDKN2A
25 verrucous carcinoma 10.1 CDKN2A MDM2
26 ewing's family of tumors 10.1 CDK4 CDKN2A
27 scrotal carcinoma 10.1 CDKN2A HMGA2
28 conventional leiomyosarcoma 10.1 CDKN2A HMGA2
29 uterine sarcoma 10.1 MDM2 SMARCB1
30 cellular schwannoma 10.1 CDKN2A MDM2
31 retroperitoneum carcinoma 10.1 CDKN2A SMARCB1
32 epithelial-myoepithelial carcinoma 10.1 HMGA2 SMARCB1
33 rhabdomyosarcoma 2 10.1 CDK4 MDM2
34 supratentorial cancer 10.1 CDKN2A MDM2
35 cerebrum cancer 10.0 CDKN2A MDM2
36 skin melanoma 10.0 CDKN2A MDM2
37 atypical teratoid rhabdoid tumor 10.0 HMGA2 SMARCB1
38 inflammatory myofibroblastic tumor 10.0 CDK4 MDM2
39 cell type benign neoplasm 10.0 CDKN2A HMGA2
40 sclerosing liposarcoma 10.0 FUS MDM2
41 infiltrating lipoma 10.0 CDK4 HMGA2 MDM2
42 salivary gland carcinoma 10.0 CDKN2A MDM2
43 infiltrating angiolipoma 10.0 CDK4 CDKN2A MDM2
44 periosteal chondrosarcoma 10.0 CDK4 CDKN2A MDM2
45 ischemic fasciitis 10.0 CDK4 CDKN2A MDM2
46 pleomorphic adenoma 10.0 HMGA2 MDM2
47 small cell sarcoma 10.0 CDK4 MDM2 SMARCB1
48 fibrosarcoma of bone 10.0 CDK4 CDKN2A MDM2
49 retinal cancer 10.0 CDK4 CDKN2A MDM2
50 ocular cancer 10.0 CDK4 CDKN2A MDM2

Graphical network of the top 20 diseases related to Atypical Lipomatous Tumor:



Diseases related to Atypical Lipomatous Tumor

Symptoms & Phenotypes for Atypical Lipomatous Tumor

MGI Mouse Phenotypes related to Atypical Lipomatous Tumor:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 8.92 CDK4 CDKN2A MDM2 SMARCB1

Drugs & Therapeutics for Atypical Lipomatous Tumor

Drugs for Atypical Lipomatous Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Rosiglitazone Approved, Investigational Phase 2 122320-73-4 77999
2
Maleic acid Experimental Phase 2 110-16-7 444266
3 Hypoglycemic Agents Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Activity and Tolerability of Pazopanib in Advanced and/or Metastatic Liposarcoma. A Phase II Clinical Trial Completed NCT01692496 Phase 2 Pazopanib
2 Rosiglitazone in Treating Patients With Liposarcoma Completed NCT00004180 Phase 2 rosiglitazone maleate
3 A Study Assessing Efficacy & Safety of Ribociclib in Patients With Advanced Well/Dedifferentiated Liposarcoma Recruiting NCT03096912 Phase 2 Ribociclib
4 Efficacy and Safety of Plitidepsin in Patients With Advanced Unresectable or Metastatic, Relapsed/Refractory, Dedifferentiated Liposarcoma (DLPS): an Exploratory Phase II Multicenter Trial Terminated NCT01876043 Phase 2 plitidepsin
5 The FGF/FGFR Signalling Pathway: Recruiting NCT03303885

Search NIH Clinical Center for Atypical Lipomatous Tumor

Genetic Tests for Atypical Lipomatous Tumor

Anatomical Context for Atypical Lipomatous Tumor

MalaCards organs/tissues related to Atypical Lipomatous Tumor:

41
Breast, Tongue, Skin, Liver, Adipocyte, Bone, Salivary Gland

Publications for Atypical Lipomatous Tumor

Articles related to Atypical Lipomatous Tumor:

(show top 50) (show all 79)
# Title Authors Year
1
Corrigendum to "Pericytic mimicry in well-differentiated liposarcoma/atypical lipomatous tumor" (Hum Pathol 2016;54:92-99). ( 29958690 )
2018
2
Well-Differentiated Liposarcoma (Atypical Lipomatous Tumor) Presenting as an Esophageal Polyp. ( 29349606 )
2018
3
A rare cause of dysphagia: Pyriform sinus atypical lipomatous tumor. ( 29940678 )
2018
4
Primary Atypical Lipomatous Tumor of the Orbit: A Case Report. ( 29403596 )
2018
5
Lipomas of the Oral Cavity: Utility of MDM2 and CDK4 in Avoiding Overdiagnosis as Atypical Lipomatous Tumor. ( 29748845 )
2018
6
Primary Breast Atypical Lipomatous Tumor/ Well-Differentiated Liposarcoma and Dedifferentiated Liposarcoma. ( 29372852 )
2018
7
Hibernoma Mimicking Atypical Lipomatous Tumor: 64 Cases of a Morphologically Distinct Subset. ( 29629919 )
2018
8
A Case of Atypical Lipomatous Tumor that Dedifferentiated with Second Recurrence after Additional Resection. ( 30214842 )
2018
9
Atypical lipomatous tumor in the ligamentum teres of liver: A case report and review of the literature. ( 30397612 )
2018
10
MDM2 RNA In Situ Hybridization for the Diagnosis of Atypical Lipomatous Tumor: A Study Evaluating DNA, RNA, and Protein Expression. ( 30520819 )
2018
11
Primary atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL) of the breast. ( 28845581 )
2017
12
Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma Developed in a Patient with Progressive Muscular Dystrophy: A Case Report and Review of the Literature. ( 28634560 )
2017
13
Endoscopic submucosal dissection of a huge esophageal atypical lipomatous tumor (well-differentiated liposarcoma) with a 4-year recurrence-free survival. ( 28719927 )
2017
14
A novel sclerosing atypical lipomatous tumor/well-differentiated liposarcoma in a 7-year-old girl: Report of a case with molecular confirmation. ( 28705709 )
2017
15
Atypical lipomatous tumor of the hand with transformation to dedifferentiated liposarcoma: a case report. ( 29209735 )
2017
16
An atypical lipomatous tumor mimicking a giant fibrovascular polyp of the hypopharynx: A case report. ( 29068974 )
2017
17
Giant atypical lipoma. ( 28954109 )
2017
18
Differential diagnosis of atypical lipomatous tumor/well-differentiated liposarcoma and dedifferentiated liposarcoma: utility of p16 in combination with MDM2 and CDK4 immunohistochemistry. ( 27597521 )
2016
19
Cellular Angiofibroma With Sarcomatous Transformation Showing Pleomorphic Liposarcoma-Like and Atypical Lipomatous Tumor-Like Features. ( 26760687 )
2016
20
Pericytic mimicry in well-differentiated liposarcoma / atypical lipomatous tumor. ( 27063472 )
2016
21
Intramuscular atypical lipomatous tumor/well-differentiated liposarcoma of the pectoralis major masquerading as a breast tumor: management and review of the literature. ( 25692417 )
2015
22
Clinical outcome of deep-seated atypical lipomatous tumor of the extremities with median-term follow-up study. ( 25498358 )
2015
23
Differentiation of lipoma and atypical lipomatous tumor by a scoring system: implication of increased vascularity on pathogenesis of liposarcoma. ( 25879189 )
2015
24
Atypical lipomatous tumor/well-differentiated liposarcoma of the gingiva: a case report and review of literature. ( 23992781 )
2014
25
Atypical lipomatous tumor with structural rearrangements involving chromosomes 3 and 8. ( 24922675 )
2014
26
FDG PET/CT findings in a rare case of giant fibrovascular polyp of the esophagus harboring atypical lipomatous tumor/well-differentiated liposarcoma. ( 24458178 )
2014
27
Adjuvant radiotherapy for extremity and trunk wall atypical lipomatous tumor/well-differentiated LPS (ALT/WD-LPS): a French Sarcoma Group (GSF-GETO) study. ( 24914041 )
2014
28
Giant atypical lipoma of the thigh. ( 24354663 )
2014
29
Atypical lipomatous tumor mimicking giant fibrovascular polyp of the esophagus: report of a case and a critical review of literature. ( 23352209 )
2013
30
MRI characteristics of lipoma and atypical lipomatous tumor/well-differentiated liposarcoma: retrospective comparison with histology and MDM2 gene amplification. ( 22987247 )
2013
31
Pleomorphic fibroma and dermal atypical lipomatous tumor: are they related? ( 23506010 )
2013
32
The General Surgeon's quandary: atypical lipomatous tumor vs lipoma, who needs a surgical oncologist? ( 24074812 )
2013
33
Atypical lipomatous tumor of the cheek - a case report. ( 23911052 )
2013
34
Deep-seated huge hibernoma of soft tissue: a rare differential diagnosis of atypical lipomatous tumor/well differentiated liposarcoma. ( 24133596 )
2013
35
Atypical lipomatous tumor/well-differentiated liposarcoma: what is it? ( 22365523 )
2012
36
Case report: atypical lipomatous tumor with unusual extensive metaplastic ossification. ( 22375305 )
2012
37
Well-differentiated liposarcoma/atypical lipomatous tumor of the oral cavity: report of three cases and review of the literature. ( 22234501 )
2012
38
Sensitivity of MDM2 amplification and unexpected multiple faint alphoid 12 (alpha 12 satellite sequences) signals in atypical lipomatous tumor. ( 22699518 )
2012
39
Giant atypical lipomatous tumor/well-differentiated liposarcoma of the neck. ( 21586964 )
2011
40
Atypical lipomatous tumor/"well-differentiated liposarcoma" of the skin clinically presenting as a skin tag: clinicopathologic, immunohistochemical, and molecular analysis of 2 cases. ( 21358383 )
2011
41
Well-differentiated liposarcoma, an atypical lipomatous tumor, of the mesentery: a case report and review of the literature. ( 21526137 )
2011
42
Atypical lipomatous tumor of the breast. ( 21931026 )
2011
43
Pleomorphic fibroma of the skin, atypical lipomatous tumor, or both? ( 21123246 )
2011
44
p53+/mdm2- atypical lipomatous tumor/well-differentiated liposarcoma in young children: an early expression of Li-Fraumeni syndrome. ( 20028212 )
2010
45
Giant hypopharyngeal atypical lipomatous tumor. ( 20032637 )
2010
46
[Lipoma and atypical lipomatous tumor within the same neoplasia: Evidence for a continuous transition]. ( 20063101 )
2010
47
Atypical lipomatous tumor of the tongue: report of a case. ( 20802543 )
2010
48
Foreign body reaction to soft tissue filler simulating atypical lipomatous tumor: report of a case. ( 21045415 )
2010
49
Well-differentiated spindle cell liposarcoma ('atypical spindle cell lipomatous tumor') does not belong to the spectrum of atypical lipomatous tumor but has a close relationship to spindle cell lipoma: clinicopathologic, immunohistochemical, and molecular analysis of six cases. ( 20228779 )
2010
50
Atypical lipomatous tumor/well-differentiated liposarcoma of the parotid gland: case report and literature review. ( 19826985 )
2009

Variations for Atypical Lipomatous Tumor

Cosmic variations for Atypical Lipomatous Tumor:

9 (show top 50) (show all 217)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM6933566 ZFHX3 soft tissue,fat,liposarcoma,NS c.7624T>C p.F2542L 16:72795058-72795058 3
2 COSM6978413 ZFHX3 soft tissue,fat,liposarcoma,NS c.448C>A p.L150M 16:72959698-72959698 3
3 COSM6922065 YES1 soft tissue,fat,liposarcoma,NS c.166A>G p.S56G 18:756662-756662 3
4 COSM3054546 XPO1 soft tissue,fat,liposarcoma,NS c.1288G>T p.V430L 2:61493011-61493011 3
5 COSM6987297 WT1 soft tissue,fat,liposarcoma,NS c.223G>A p.E75K 11:32434919-32434919 3
6 COSM6986268 TSC1 soft tissue,fat,liposarcoma,NS c.1079C>A p.T360N 9:132911064-132911064 3
7 COSM11333 TP53 soft tissue,fat,liposarcoma,NS c.499C>T p.Q167* 17:7675113-7675113 3
8 COSM44723 TP53 soft tissue,fat,liposarcoma,NS c.674T>C p.V225A 17:7674289-7674289 3
9 COSM10646 TP53 soft tissue,fat,liposarcoma,NS c.725G>A p.C242Y 17:7674238-7674238 3
10 COSM44094 TP53 soft tissue,fat,liposarcoma,NS c.716A>G p.N239S 17:7674247-7674247 3
11 COSM10659 TP53 soft tissue,fat,liposarcoma,NS c.817C>T p.R273C 17:7673803-7673803 3
12 COSM10648 TP53 soft tissue,fat,liposarcoma,NS c.524G>A p.R175H 17:7675088-7675088 3
13 COSM10672 TP53 soft tissue,fat,liposarcoma,NS c.577C>T p.H193Y 17:7674954-7674954 3
14 COSM43663 TP53 soft tissue,fat,liposarcoma,NS c.826G>C p.A276P 17:7673794-7673794 3
15 COSM10941 TP53 soft tissue,fat,liposarcoma,NS c.730G>A p.G244S 17:7674233-7674233 3
16 COSM44512 TP53 soft tissue,fat,liposarcoma,NS c.740A>G p.N247S 17:7674223-7674223 3
17 COSM10647 TP53 soft tissue,fat,liposarcoma,NS c.404G>T p.C135F 17:7675208-7675208 3
18 COSM10656 TP53 soft tissue,fat,liposarcoma,NS c.742C>T p.R248W 17:7674221-7674221 3
19 COSM45794 TP53 soft tissue,fat,liposarcoma,NS c.421T>G p.C141G 17:7675191-7675191 3
20 COSM11059 TP53 soft tissue,fat,liposarcoma,NS c.713G>A p.C238Y 17:7674250-7674250 3
21 COSM44112 TP53 soft tissue,fat,liposarcoma,NS c.640C>T p.H214Y 17:7674891-7674891 3
22 COSM10654 TP53 soft tissue,fat,liposarcoma,NS c.637C>T p.R213* 17:7674894-7674894 3
23 COSM11245 TP53 soft tissue,fat,liposarcoma,NS c.430C>T p.Q144* 17:7675182-7675182 3
24 COSM43632 TP53 soft tissue,fat,liposarcoma,NS c.493C>T p.Q165* 17:7675119-7675119 3
25 COSM10731 TP53 soft tissue,fat,liposarcoma,NS c.707A>G p.Y236C 17:7674256-7674256 3
26 COSM6901 TP53 soft tissue,fat,liposarcoma,NS c.559+1G>A p.? 17:7675052-7675052 3
27 COSM4465309 TNFAIP3 soft tissue,fat,liposarcoma,NS c.1376C>T p.S459L 6:137878821-137878821 3
28 COSM6848516 TET2 soft tissue,fat,liposarcoma,NS c.3809C>T p.T1270I 4:105259624-105259624 3
29 COSM6924539 SMARCA4 soft tissue,fat,liposarcoma,NS c.3940G>T p.D1314Y 19:11034189-11034189 3
30 COSM7002390 SETD2 soft tissue,fat,liposarcoma,NS c.4604C>T p.T1535I 3:47062343-47062343 3
31 COSM6921522 SDHA soft tissue,fat,liposarcoma,NS c.664T>G p.L222V 5:228227-228227 3
32 COSM6942711 ROS1 soft tissue,fat,liposarcoma,NS c.1453T>C p.S485P 6:117389656-117389656 3
33 COSM1437480 RICTOR soft tissue,fat,liposarcoma,NS c.3404C>T p.T1135M 5:38950444-38950444 3
34 COSM6967634 RBM10 soft tissue,fat,liposarcoma,NS c.443A>G p.Q148R 23:47173138-47173138 3
35 COSM1651764 RB1 soft tissue,fat,liposarcoma,NS c.1818T>A p.Y606* 13:48456207-48456207 3
36 COSM6966300 RB1 soft tissue,fat,liposarcoma,NS c.2632G>A p.D878N 13:48476812-48476812 3
37 COSM6906362 RAF1 soft tissue,fat,liposarcoma,NS c.1141G>A p.D381N 3:12591760-12591760 3
38 COSM5106 PTEN soft tissue,fat,liposarcoma,NS c.335T>C p.L112P 10:87933094-87933094 3
39 COSM5135 PTEN soft tissue,fat,liposarcoma,NS c.106G>A p.G36R 10:87894051-87894051 3
40 COSM5039 PTEN soft tissue,fat,liposarcoma,NS c.518G>A p.R173H 10:87952143-87952143 3
41 COSM1167954 PTEN soft tissue,fat,liposarcoma,NS c.485A>T p.D162V 10:87933244-87933244 3
42 COSM5198 PTEN soft tissue,fat,liposarcoma,NS c.72C>G p.D24E 10:87864541-87864541 3
43 COSM3416650 POLE soft tissue,fat,liposarcoma,NS c.2275C>T p.R759C 12:132667547-132667547 3
44 COSM6987724 PLK2 soft tissue,fat,liposarcoma,NS c.1337G>C p.R446P 5:58456073-58456073 3
45 COSM6967036 PLCG2 soft tissue,fat,liposarcoma,NS c.3232C>T p.R1078* 16:81938834-81938834 3
46 COSM2155617 PIK3R1 soft tissue,fat,liposarcoma,NS c.1135A>G p.K379E 5:68293319-68293319 3
47 COSM775 PIK3CA soft tissue,fat,liposarcoma,NS c.3140A>G p.H1047R 3:179234297-179234297 3
48 COSM763 PIK3CA soft tissue,fat,liposarcoma,NS c.1633G>A p.E545K 3:179218303-179218303 3
49 COSM760 PIK3CA soft tissue,fat,liposarcoma,NS c.1624G>A p.E542K 3:179218294-179218294 3
50 COSM754 PIK3CA soft tissue,fat,liposarcoma,NS c.1035T>A p.N345K 3:179203765-179203765 3

Expression for Atypical Lipomatous Tumor

Search GEO for disease gene expression data for Atypical Lipomatous Tumor.

Pathways for Atypical Lipomatous Tumor

Pathways related to Atypical Lipomatous Tumor according to GeneCards Suite gene sharing:

(show all 23)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.76 CDK4 CDKN2A HMGA2 MDM2
2
Show member pathways
12.46 CDK4 CDKN2A MDM2
3
Show member pathways
12.45 CDK4 CDKN2A SMARCB1
4
Show member pathways
12.26 CDK4 CDKN2A MDM2
5 12.19 CDKN2A HMGA2 MDM2
6 12.17 CDK4 CDKN2A MDM2
7 12.08 FUS HMGA2 SMARCB1
8
Show member pathways
12.02 CDK4 CDKN2A MDM2
9 11.99 CDK4 CDKN2A MDM2
10 11.91 CDK4 CDKN2A MDM2
11 11.77 FUS HMGA2 MDM2
12 11.64 CDK4 CDKN2A MDM2
13 11.46 CDKN2A MDM2
14
Show member pathways
11.45 CDKN2A MDM2
15 11.38 CDK4 CDKN2A MDM2
16 11.33 MDM2 SMARCB1
17 11.31 CDKN2A MDM2
18 11.22 CDK4 MDM2
19 11.19 CDK4 MDM2
20 11 CDK4 CDKN2A MDM2
21 10.75 CDKN2A MDM2
22
Show member pathways
10.71 CDKN2A MDM2
23 10.3 CDK4 CDKN2A MDM2

GO Terms for Atypical Lipomatous Tumor

Cellular components related to Atypical Lipomatous Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nucleoplasm GO:0005654 9.43 CDK4 CDKN2A FUS HMGA2 MDM2 SMARCB1
2 senescence-associated heterochromatin focus GO:0035985 8.62 CDKN2A HMGA2

Biological processes related to Atypical Lipomatous Tumor according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.67 CDKN2A HMGA2 MDM2
2 positive regulation of apoptotic process GO:0043065 9.63 CDK4 CDKN2A HMGA2
3 cell cycle GO:0007049 9.62 CDK4 CDKN2A HMGA2 SMARCB1
4 positive regulation of cell cycle GO:0045787 9.48 CDK4 MDM2
5 protein destabilization GO:0031648 9.43 CDKN2A MDM2
6 protein sumoylation GO:0016925 9.4 CDKN2A MDM2
7 negative regulation of cell cycle arrest GO:0071157 9.37 CDK4 MDM2
8 positive regulation of cellular senescence GO:2000774 9.26 CDKN2A HMGA2
9 amyloid fibril formation GO:1990000 9.16 CDKN2A MDM2
10 obsolete negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle GO:0031658 8.96 CDK4 CDKN2A
11 senescence-associated heterochromatin focus assembly GO:0035986 8.62 CDKN2A HMGA2

Molecular functions related to Atypical Lipomatous Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 p53 binding GO:0002039 9.26 MDM2 SMARCB1
2 nucleosomal DNA binding GO:0031492 9.16 HMGA2 SMARCB1
3 disordered domain specific binding GO:0097718 8.96 CDKN2A MDM2
4 SUMO transferase activity GO:0019789 8.62 CDKN2A MDM2

Sources for Atypical Lipomatous Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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