MCID: ATY009
MIFTS: 26

Atypical Polypoid Adenomyoma

Categories: Cancer diseases

Aliases & Classifications for Atypical Polypoid Adenomyoma

MalaCards integrated aliases for Atypical Polypoid Adenomyoma:

Name: Atypical Polypoid Adenomyoma 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:4993
NCIt 50 C6895
SNOMED-CT 67 40293003
UMLS 70 C1300347

Summaries for Atypical Polypoid Adenomyoma

Disease Ontology : 12 An adenomyoma that is a biphasic polypoid lesion consisting of a myofibroblastic stromal component and an endometrial intraepithelial neoplasm.

MalaCards based summary : Atypical Polypoid Adenomyoma is related to adenomyosis and endometrial adenocarcinoma. An important gene associated with Atypical Polypoid Adenomyoma is CALD1 (Caldesmon 1). Affiliated tissues include uterus, smooth muscle and ovary, and related phenotype is cellular.

Wikipedia : 73 Atypical polypoid adenomyoma (APA) is a rare uncommon benign tumour of the... more...

Related Diseases for Atypical Polypoid Adenomyoma

Diseases related to Atypical Polypoid Adenomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 143)
# Related Disease Score Top Affiliating Genes
1 adenomyosis 30.7 MME CTNNB1
2 endometrial adenocarcinoma 30.7 MLH1 CTNNB1 CDKN2A
3 myoma 30.4 MME MED12 CALD1
4 endometrioid ovary carcinoma 30.4 MLH1 CTNNB1
5 adenomyoma 30.3 MME MLH1 MED12 CTNNB1 CDKN2A CALD1
6 endometrial cancer 30.3 MME MLH1 CTNNB1 CDKN2A
7 carcinosarcoma 30.0 MME CTNNB1 CDKN2A
8 smooth muscle tumor 30.0 MME MED12 CALD1
9 uterine corpus atypical polypoid adenomyoma 11.7
10 cervical atypical polypoid adenomyoma 11.5
11 endometrial hyperplasia 10.5
12 adenosarcoma 10.4
13 adenofibroma 10.4
14 vaginal endometrial stromal tumor 10.3 MME CALD1
15 endometrial stromal tumor 10.3 MME CALD1
16 mixed endometrial stromal and smooth muscle tumor 10.3 MME CALD1
17 fallopian tube leiomyoma 10.3 MME CALD1
18 urethra leiomyoma 10.3 MME CALD1
19 fallopian tube benign neoplasm 10.3 MME CALD1
20 breast myofibroblastoma 10.3 MME CALD1
21 subareolar duct papillomatosis 10.3 MME CALD1
22 lung combined type small cell carcinoma 10.3 MME CALD1
23 cervical mucinous adenocarcinoma 10.3 MME CALD1
24 nipple benign neoplasm 10.3 MME CALD1
25 cervical polyp 10.2 MME CALD1
26 sarcomatoid squamous cell skin carcinoma 10.2 MME CALD1
27 adenocarcinoma 10.2
28 infertility 10.2
29 rare tumor 10.2
30 uterus perivascular epithelioid cell tumor 10.2 MME CALD1
31 vaginal endometrial stromal sarcoma 10.2 MME CALD1
32 vulvar leiomyoma 10.2 MME CALD1
33 endometrial stromal nodule 10.2 MME CALD1
34 ovarian endometrioid stromal sarcoma 10.2 MME CALD1
35 vagina sarcoma 10.2 MME CALD1
36 urethral benign neoplasm 10.2 MME CALD1
37 cervical adenoma malignum 10.2 MME CALD1
38 cervical adenosarcoma 10.2 MME CALD1
39 ovary sarcoma 10.2 MME CALD1
40 intravascular fasciitis 10.2 CTNNB1 CALD1
41 vulvar benign neoplasm 10.2 MME CALD1
42 sweat gland benign neoplasm 10.2 MME CALD1
43 perivascular tumor 10.2 MME CALD1
44 conventional fibrosarcoma 10.2 CTNNB1 CALD1
45 intrahepatic bile duct adenoma 10.2 MME CTNNB1
46 pseudosarcomatous fibromatosis 10.2 CTNNB1 CALD1
47 mesenchymal cell neoplasm 10.2 MME CALD1
48 infiltrating angiolipoma 10.2 CDKN2A CALD1
49 inflammatory liposarcoma 10.2 MME CDKN2A
50 vulvar intraepithelial neoplasia 10.1 CTNNB1 CDKN2A

Graphical network of the top 20 diseases related to Atypical Polypoid Adenomyoma:



Diseases related to Atypical Polypoid Adenomyoma

Symptoms & Phenotypes for Atypical Polypoid Adenomyoma

MGI Mouse Phenotypes related to Atypical Polypoid Adenomyoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.17 CDKN2A CTNNB1 EMG1 MED12 MLH1 MME

Drugs & Therapeutics for Atypical Polypoid Adenomyoma

Search Clinical Trials , NIH Clinical Center for Atypical Polypoid Adenomyoma

Genetic Tests for Atypical Polypoid Adenomyoma

Anatomical Context for Atypical Polypoid Adenomyoma

MalaCards organs/tissues related to Atypical Polypoid Adenomyoma:

40
Uterus, Smooth Muscle, Ovary, Cervix

Publications for Atypical Polypoid Adenomyoma

Articles related to Atypical Polypoid Adenomyoma:

(show top 50) (show all 118)
# Title Authors PMID Year
1
Atypical polypoid adenomyoma. 61
33795408 2021
2
Patterns of SATB2 and p16 Reactivity Aid Distinction of Atypical Polypoid Adenomyoma from Myoinvasive Endometrioid Carcinoma and Benign Adenomyomatous Polyp on Endometrial Sampling. 61
33459390 2021
3
Atypical polypoid adenomyoma of the endometrium: diagnosis and treatment. A case report. 61
33393525 2020
4
Significance of stromal markers in atypical polypoid adenomyoma. 61
32823231 2020
5
Immunophenotype of Atypical Polypoid Adenomyoma of the Uterus: Diagnostic Value and Insight on Pathogenesis. 61
31855579 2020
6
A case of endometrial carcinoma progressed during pregnancy resulting in fetal death. 61
32582523 2020
7
Atypical polypoid adenomyoma follow-up and management: Systematic review of case reports and series and meta-analysis. 61
32590732 2020
8
Endometrial Endometrioid Carcinoma With Ovarian Metastasis Showing Morula-like Features in a Patient With Cowden Syndrome: A Case Report. 61
30676432 2020
9
Mutations of RAS genes in endometrial polyps. 61
31638232 2019
10
Stromal p16 Expression Helps Distinguish Atypical Polypoid Adenomyoma From Myoinvasive Endometrioid Carcinoma of the Uterus. 61
31600177 2019
11
Peritoneal Keratin Granulomatosis Is a Clinical and Radiological Mimicker of Endometrial Adenocarcinoma With Peritoneal Involvement. 61
31113276 2019
12
SATB2 is Consistently Expressed in Squamous Morules Associated With Endometrioid Proliferative Lesions and in the Stroma of Atypical Polypoid Adenomyoma. 61
30085940 2019
13
Atypical polypoid adenomyoma treated by hysteroscopy with photodynamic diagnosis using 5-aminolevulinic acid: A case report. 61
31252140 2019
14
Management of women with atypical polypoid adenomyoma of the uterus: A quantitative systematic review. 61
30714089 2019
15
Cytomorphological features of atypical polypoid adenomyoma of the endometrium. 61
30556192 2019
16
A case of incidental endometrial adenocarcinoma diagnosed in early pregnancy and managed conservatively. 61
30993161 2019
17
Atypical polypoid adenomyoma of the uterus: A reappraisal of the clinicopathological and immunohistochemical features. 61
30661903 2019
18
Clinicopathological and immunohistochemical features of uterine adenomyomatous polyps. 61
30339971 2019
19
Uncommon Mixed Endometrial-Myometrial Benign Tumors of the Reproductive Tract: Literature Review. 61
30889596 2019
20
Successful laparotomy tumor resection and levonorgestrel-releasing intrauterine system for atypical polypoid adenomyoma. 61
30094884 2019
21
Management of atypical polypoid adenomyoma of the uterus: A single center's experience. 61
29561413 2018
22
Maintenance hormonal therapy after treatment with medroxyprogesterone acetate for patients with atypical polypoid adenomyoma. 61
29351618 2018
23
Pregnant outcomes of atypical polypoid adenomyoma treated with progestin therapy. 61
29121416 2018
24
A case of rapidly-growing atypical polypoid adenomyoma which was histologically diagnosed before operation and removed by a laparoscopic resection. 61
29458879 2018
25
Hysteroscopic Transcervical Resection for Atypical Polypoid Adenomyoma of the Uterus: A Valid, Fertility-Preserving Option. 61
29038039 2018
26
Recurrent atypical polypoid adenomyoma and pregnancy: A new conservative approach with levonorgestrel-releasing intrauterine system. 61
28761925 2017
27
Cytological features of atypical polypoid adenomyoma of the endometrium: A case report with literature review. 61
28160434 2017
28
[Atypical polypoid adenomyoma of the uterus: a clinicopathological review of 27 cases]. 61
28441840 2017
29
Second Opinion Expert Pathology in Endometrial Cancer: Potential Clinical Implications. 61
27922981 2017
30
[Pitfalls in the histopathological diagnostics of endometrial carcinoma and its precursors : Clinically relevant differential diagnoses, avoidance of false positive diagnoses]. 61
27681950 2016
31
Positron Emission Tomography Findings in Atypical Polypoid Adenomyoma. 61
27134711 2016
32
A mixed carcinoma of the uterus arising from an atypical polypoid adenomyoma: a case report. 61
29943938 2016
33
A practical approach to the diagnosis of mixed epithelial and mesenchymal tumours of the uterus. 61
26715175 2016
34
Long-term outcomes of fertility-sparing treatment of atypical polypoid adenomyoma with medroxyprogesterone acetate. 61
26209972 2016
35
Endocervical Atypical Polypoid Adenomyoma. 61
26304721 2016
36
Atypical Polypoid Adenomyoma of the Uterus: An Immunohistochemical and Molecular Study of 21 Cases. 61
25828387 2015
37
Hysteroscopic transcervical resection is useful to diagnose myometrial invasion in atypical polypoid adenomyoma coexisting with atypical endometrial hyperplasia or endometrial cancer with suspicious myometrial invasion. 61
25491392 2015
38
MR manifestations of uterine polypoid adenomyoma. 61
25516215 2015
39
Magnetic resonance imaging findings in atypical polypoid adenomyoma. 61
25286280 2015
40
Coexistence of endometrioid adenocarcinoma in atypical polypoid adenomyoma. 61
25612673 2014
41
[Clinicopathologic analysis of 14 cases of atypical polypoid adenomyoma of endometrium with the emphasis on its cancerous transformation]. 61
25487451 2014
42
Adenomyomatous Polyp of the Endometrium With Prominent Epithelioid Smooth Muscle Differentiation: Report of Two Cases of a Hitherto Undescribed Lesion. 61
23926192 2014
43
A case of endometrioid adenocarcinoma developing 8 years after conservative management for atypical polypoid adenomyoma. 61
24707458 2014
44
[Atypical polypoid adenomyoma: retrospective study about 8 cases from Jeanne-de-Flandre Hospital between 1996 and 2008]. 61
22306097 2014
45
Frequent β-catenin gene mutations in atypical polypoid adenomyoma of the uterus. 61
24182564 2014
46
Benign and malignant tumor of the uterine body with broccoli sign: MR imaging features for differential diagnosis. 61
23719762 2013
47
A multiple perspectives on atypical polypoid adenomyoma of uterus. 61
23527553 2013
48
Clinical management of atypical polypoid adenomyoma of the uterus. A clinicopathological review of 29 cases. 61
23290989 2013
49
[Case of atypical polypoid adenomyoma of the uterine cevix]. 61
23805464 2013
50
Atypical polypoid adenomyoma mixed with endometrioid carcinoma: a case report. 61
23590013 2013

Variations for Atypical Polypoid Adenomyoma

Expression for Atypical Polypoid Adenomyoma

Search GEO for disease gene expression data for Atypical Polypoid Adenomyoma.

Pathways for Atypical Polypoid Adenomyoma

GO Terms for Atypical Polypoid Adenomyoma

Biological processes related to Atypical Polypoid Adenomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 stem cell population maintenance GO:0019827 9.26 MED12 CTNNB1
2 embryonic organ development GO:0048568 9.16 MED12 CTNNB1
3 replicative senescence GO:0090399 8.96 MME CDKN2A
4 embryonic brain development GO:1990403 8.62 MED12 CTNNB1

Molecular functions related to Atypical Polypoid Adenomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transcription factor binding GO:0008134 9.33 MED12 CTNNB1 CDKN2A
2 disordered domain specific binding GO:0097718 8.96 CTNNB1 CDKN2A
3 chromatin binding GO:0003682 8.92 SATB2 MLH1 MED12 CTNNB1

Sources for Atypical Polypoid Adenomyoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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