MCID: ATY009
MIFTS: 28

Atypical Polypoid Adenomyoma

Categories: Cancer diseases
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Aliases & Classifications for Atypical Polypoid Adenomyoma

MalaCards integrated aliases for Atypical Polypoid Adenomyoma:

Name: Atypical Polypoid Adenomyoma 11 14 71 75

Classifications:



External Ids:

Disease Ontology 11 DOID:4993
NCIt 49 C6895
SNOMED-CT 68 40293003
UMLS 71 C1300347

Summaries for Atypical Polypoid Adenomyoma

Disease Ontology: 11 An adenomyoma that is a biphasic polypoid lesion consisting of a myofibroblastic stromal component and an endometrial intraepithelial neoplasm.

MalaCards based summary: Atypical Polypoid Adenomyoma is related to adenomyoma and myoma. An important gene associated with Atypical Polypoid Adenomyoma is MME (Membrane Metalloendopeptidase), and among its related pathways/superpathways are Regulation of nuclear beta catenin signaling and target gene transcription and Peptide hormone metabolism. Affiliated tissues include uterus, smooth muscle and cervix, and related phenotypes are growth/size/body region and cellular

Wikipedia: 75 Atypical polypoid adenomyoma (APA) is a rare benign tumour of the... more...

Related Diseases for Atypical Polypoid Adenomyoma

Diseases related to Atypical Polypoid Adenomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 126)
# Related Disease Score Top Affiliating Genes
1 adenomyoma 31.2 MME MED12 CTNNB1 CALD1
2 myoma 30.6 MME MED12 CALD1
3 adenosarcoma 30.4 MME JAZF1 CALD1
4 mesenchymal cell neoplasm 30.4 MME CTNNB1 CALD1
5 mixed cell type cancer 30.3 MME CTNNB1 CALD1
6 smooth muscle tumor 30.2 MME MED12 CALD1
7 carcinosarcoma 30.1 MME CTNNB1
8 uterine corpus atypical polypoid adenomyoma 11.7
9 cervical atypical polypoid adenomyoma 11.5
10 endometrial cancer 10.8
11 endometrial hyperplasia 10.6
12 endometrial adenocarcinoma 10.6
13 adenomyosis 10.5
14 adenofibroma 10.4
15 rare tumor 10.3
16 ovarian cancer 10.3
17 down syndrome 10.3
18 adenocarcinoma 10.3
19 turner syndrome 10.3
20 vaginal endometrial stromal tumor 10.2 MME CALD1
21 mixed endometrial stromal and smooth muscle tumor 10.2 MME CALD1
22 fallopian tube leiomyoma 10.2 MME CALD1
23 urethra leiomyoma 10.2 MME CALD1
24 breast leiomyoma 10.2 MME CALD1
25 fallopian tube benign neoplasm 10.2 MME CALD1
26 subareolar duct papillomatosis 10.2 MME CALD1
27 nipple benign neoplasm 10.2 MME CALD1
28 breast myofibroblastoma 10.2 MME CALD1
29 cutaneous leiomyosarcoma 10.2 MME CALD1
30 cervical polyp 10.2 MME CALD1
31 uterus perivascular epithelioid cell tumor 10.2 MME CALD1
32 perivascular epithelioid cell tumor 10.2 MME CALD1
33 epithelioid leiomyosarcoma 10.2 MME CALD1
34 skin sarcoma 10.2 MME CALD1
35 sarcomatoid squamous cell skin carcinoma 10.2 MME CALD1
36 vulvar leiomyoma 10.2 MME CALD1
37 diffuse peritoneal leiomyomatosis 10.2 MED12 CALD1
38 peritoneal benign neoplasm 10.2 MED12 CALD1
39 urethral benign neoplasm 10.2 MME CALD1
40 bizarre leiomyoma 10.2 MED12 CALD1
41 leiomyoma cutis 10.2 MED12 CALD1
42 breast malignant phyllodes tumor 10.1 MME MED12
43 dermis tumor 10.1 MED12 CALD1
44 vaginal cancer 10.1 MME CALD1
45 sweat gland benign neoplasm 10.1 MME CALD1
46 perivascular tumor 10.1 MME CALD1
47 gallbladder carcinoma in situ 10.1 MME CDX2
48 extraosseous osteosarcoma 10.1 SATB2 CALD1
49 female urethral cancer 10.1 MME CDX2
50 cutaneous fibrous histiocytoma 10.1 MME CALD1

Graphical network of the top 20 diseases related to Atypical Polypoid Adenomyoma:



Diseases related to Atypical Polypoid Adenomyoma

Symptoms & Phenotypes for Atypical Polypoid Adenomyoma

MGI Mouse Phenotypes related to Atypical Polypoid Adenomyoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.5 CALD1 CDX2 CTNNB1 EMG1 JAZF1 MED12
2 cellular MP:0005384 9.17 CDX2 CTNNB1 EMG1 JAZF1 MED12 MME

Drugs & Therapeutics for Atypical Polypoid Adenomyoma

Search Clinical Trials, NIH Clinical Center for Atypical Polypoid Adenomyoma

Genetic Tests for Atypical Polypoid Adenomyoma

Anatomical Context for Atypical Polypoid Adenomyoma

Organs/tissues related to Atypical Polypoid Adenomyoma:

MalaCards : Uterus, Smooth Muscle, Cervix, Ovary

Publications for Atypical Polypoid Adenomyoma

Articles related to Atypical Polypoid Adenomyoma:

(show top 50) (show all 125)
# Title Authors PMID Year
1
Oncologic outcomes of conservative treatment of atypical polypoid adenomyoma of the uterus: A two-center experience. 62
34921691 2022
2
An Unusual Imaging of Atypical Polypoid Adenomyoma in a 21-Year-Old Woman. 62
34929397 2022
3
MRI and Transvaginal Ultrasound Findings of Atypical Polypoid Adenomyoma: A Case Report. 62
35256047 2022
4
Clinical analysis of 44 cases of atypical polypoid adenomyoma of the uterus. 62
35246106 2022
5
Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update. 62
35204457 2022
6
Hysteroscopic treatment assisted by photodynamic diagnosis for atypical polypoid adenomyoma: A report of two cases. 62
34673272 2021
7
Patterns of SATB2 and p16 reactivity aid in the distinction of atypical polypoid adenomyoma from myoinvasive endometrioid carcinoma and benign adenomyomatous polyp on endometrial sampling. 62
33459390 2021
8
Atypical Polypoid Adenomyoma (APAM). 62
34102788 2021
9
Atypical polypoid adenomyoma. 62
33795408 2021
10
Atypical polypoid adenomyoma of the endometrium: diagnosis and treatment. A case report. 62
33393525 2020
11
Significance of stromal markers in atypical polypoid adenomyoma. 62
32823231 2020
12
Immunophenotype of Atypical Polypoid Adenomyoma of the Uterus: Diagnostic Value and Insight on Pathogenesis. 62
31855579 2020
13
A case of endometrial carcinoma progressed during pregnancy resulting in fetal death. 62
32582523 2020
14
Atypical polypoid adenomyoma follow-up and management: Systematic review of case reports and series and meta-analysis. 62
32590732 2020
15
Endometrial Endometrioid Carcinoma With Ovarian Metastasis Showing Morula-like Features in a Patient With Cowden Syndrome: A Case Report. 62
30676432 2020
16
Mutations of RAS genes in endometrial polyps. 62
31638232 2019
17
Stromal p16 Expression Helps Distinguish Atypical Polypoid Adenomyoma From Myoinvasive Endometrioid Carcinoma of the Uterus. 62
31600177 2019
18
Peritoneal Keratin Granulomatosis Is a Clinical and Radiological Mimicker of Endometrial Adenocarcinoma With Peritoneal Involvement. 62
31113276 2019
19
Atypical polypoid adenomyoma treated by hysteroscopy with photodynamic diagnosis using 5-aminolevulinic acid: A case report. 62
31252140 2019
20
SATB2 is Consistently Expressed in Squamous Morules Associated With Endometrioid Proliferative Lesions and in the Stroma of Atypical Polypoid Adenomyoma. 62
30085940 2019
21
Management of women with atypical polypoid adenomyoma of the uterus: A quantitative systematic review. 62
30714089 2019
22
Cytomorphological features of atypical polypoid adenomyoma of the endometrium. 62
30556192 2019
23
A case of incidental endometrial adenocarcinoma diagnosed in early pregnancy and managed conservatively. 62
30993161 2019
24
Atypical polypoid adenomyoma of the uterus: A reappraisal of the clinicopathological and immunohistochemical features. 62
30661903 2019
25
Clinicopathological and immunohistochemical features of uterine adenomyomatous polyps. 62
30339971 2019
26
Uncommon Mixed Endometrial-Myometrial Benign Tumors of the Reproductive Tract: Literature Review. 62
30889596 2019
27
Successful laparotomy tumor resection and levonorgestrel-releasing intrauterine system for atypical polypoid adenomyoma. 62
30094884 2019
28
Management of atypical polypoid adenomyoma of the uterus: A single center's experience. 62
29561413 2018
29
Maintenance hormonal therapy after treatment with medroxyprogesterone acetate for patients with atypical polypoid adenomyoma. 62
29351618 2018
30
A case of rapidly-growing atypical polypoid adenomyoma which was histologically diagnosed before operation and removed by a laparoscopic resection. 62
29458879 2018
31
Pregnant outcomes of atypical polypoid adenomyoma treated with progestin therapy. 62
29121416 2018
32
Hysteroscopic Transcervical Resection for Atypical Polypoid Adenomyoma of the Uterus: A Valid, Fertility-Preserving Option. 62
29038039 2018
33
Recurrent atypical polypoid adenomyoma and pregnancy: A new conservative approach with levonorgestrel-releasing intrauterine system. 62
28761925 2017
34
[Atypical polypoid adenomyoma of the uterus: a clinicopathological review of 27 cases]. 62
28441840 2017
35
Cytological features of atypical polypoid adenomyoma of the endometrium: A case report with literature review. 62
28160434 2017
36
Second Opinion Expert Pathology in Endometrial Cancer: Potential Clinical Implications. 62
27922981 2017
37
[Pitfalls in the histopathological diagnostics of endometrial carcinoma and its precursors : Clinically relevant differential diagnoses, avoidance of false positive diagnoses]. 62
27681950 2016
38
Positron Emission Tomography Findings in Atypical Polypoid Adenomyoma. 62
27134711 2016
39
A mixed carcinoma of the uterus arising from an atypical polypoid adenomyoma: a case report. 62
29943938 2016
40
A practical approach to the diagnosis of mixed epithelial and mesenchymal tumours of the uterus. 62
26715175 2016
41
Long-term outcomes of fertility-sparing treatment of atypical polypoid adenomyoma with medroxyprogesterone acetate. 62
26209972 2016
42
Endocervical Atypical Polypoid Adenomyoma. 62
26304721 2016
43
Atypical Polypoid Adenomyoma of the Uterus: An Immunohistochemical and Molecular Study of 21 Cases. 62
25828387 2015
44
Hysteroscopic transcervical resection is useful to diagnose myometrial invasion in atypical polypoid adenomyoma coexisting with atypical endometrial hyperplasia or endometrial cancer with suspicious myometrial invasion. 62
25491392 2015
45
MR manifestations of uterine polypoid adenomyoma. 62
25516215 2015
46
Magnetic resonance imaging findings in atypical polypoid adenomyoma. 62
25286280 2015
47
Coexistence of endometrioid adenocarcinoma in atypical polypoid adenomyoma. 62
25612673 2014
48
[Clinicopathologic analysis of 14 cases of atypical polypoid adenomyoma of endometrium with the emphasis on its cancerous transformation]. 62
25487451 2014
49
Adenomyomatous Polyp of the Endometrium With Prominent Epithelioid Smooth Muscle Differentiation: Report of Two Cases of a Hitherto Undescribed Lesion. 62
23926192 2014
50
A case of endometrioid adenocarcinoma developing 8 years after conservative management for atypical polypoid adenomyoma. 62
24707458 2014

Variations for Atypical Polypoid Adenomyoma

Expression for Atypical Polypoid Adenomyoma

Search GEO for disease gene expression data for Atypical Polypoid Adenomyoma.

Pathways for Atypical Polypoid Adenomyoma

GO Terms for Atypical Polypoid Adenomyoma

Biological processes related to Atypical Polypoid Adenomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blastocyst development GO:0001824 9.33 EMG1 CDX2
2 embryonic organ development GO:0048568 9.26 MED12 CTNNB1
3 anterior/posterior axis specification GO:0009948 9.26 CTNNB1 CDX2
4 embryonic brain development GO:1990403 8.92 MED12 CTNNB1

Sources for Atypical Polypoid Adenomyoma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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