MCID: ATY009
MIFTS: 29

Atypical Polypoid Adenomyoma

Categories: Cancer diseases

Aliases & Classifications for Atypical Polypoid Adenomyoma

MalaCards integrated aliases for Atypical Polypoid Adenomyoma:

Name: Atypical Polypoid Adenomyoma 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:4993
NCIt 51 C6895
SNOMED-CT 69 40293003
UMLS 74 C1300347

Summaries for Atypical Polypoid Adenomyoma

Disease Ontology : 12 An adenomyoma that is a biphasic polypoid lesion consisting of a myofibroblastic stromal component and an endometrial intraepithelial neoplasm.

MalaCards based summary : Atypical Polypoid Adenomyoma is related to adenomyoma and endometrial adenocarcinoma. An important gene associated with Atypical Polypoid Adenomyoma is MME (Membrane Metalloendopeptidase), and among its related pathways/superpathways are Thyroid hormone signaling pathway and Regulation of Wnt-mediated beta catenin signaling and target gene transcription. Affiliated tissues include uterus, ovary and cervix, and related phenotypes are cellular and embryo

Wikipedia : 77 Atypical polypoid adenomyoma (APA) is a rare uncommon benign tumour of the... more...

Related Diseases for Atypical Polypoid Adenomyoma

Diseases related to Atypical Polypoid Adenomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 37)
# Related Disease Score Top Affiliating Genes
1 adenomyoma 31.3 CTNNB1 MLH1 MME
2 endometrial adenocarcinoma 30.4 CTNNB1 MLH1
3 endometrial cancer 30.2 CTNNB1 MLH1 MME
4 uterine corpus atypical polypoid adenomyoma 12.8
5 cervical atypical polypoid adenomyoma 12.5
6 adenocarcinoma 10.5
7 endometrial hyperplasia 10.3
8 psammomatous meningioma 10.2 CTNNB1 MME
9 carcinosarcoma 10.1 CTNNB1 MME
10 breast benign neoplasm 10.1 MED12 MME
11 thoracic benign neoplasm 10.1 MED12 MME
12 breast fibroadenoma 10.1 MED12 MME
13 ovarian cancer 1 10.1
14 hyperprolactinemia 10.1
15 cervical adenocarcinoma 10.1
16 endometrioid ovary carcinoma 10.1
17 cowden syndrome 10.1
18 intestinal benign neoplasm 10.1 CTNNB1 MLH1
19 uterine carcinosarcoma 10.1 CTNNB1 MME
20 mismatch repair cancer syndrome 10.1 CTNNB1 MLH1
21 uterine anomalies 10.1 CTNNB1 MLH1
22 colorectal adenoma 10.1 CTNNB1 MLH1
23 cell type benign neoplasm 10.1 CTNNB1 MLH1
24 colonic disease 10.1 CTNNB1 MLH1
25 colorectal adenocarcinoma 10.1 CTNNB1 MLH1
26 stomach disease 10.1 CTNNB1 MLH1
27 female reproductive system disease 10.0 CTNNB1 MLH1
28 reproductive system disease 10.0 CTNNB1 MLH1
29 leiomyoma 10.0 MED12 MME
30 intestinal disease 10.0 CTNNB1 MLH1
31 gastrointestinal system cancer 10.0 CTNNB1 MLH1
32 endocrine gland cancer 9.9 CTNNB1 MLH1
33 familial adenomatous polyposis 9.9 CTNNB1 MLH1
34 anus, imperforate 9.9 MED12 SATB2
35 gastrointestinal system disease 9.9 CTNNB1 MLH1
36 lynch syndrome 9.8 CTNNB1 MLH1
37 ulcerative colitis 9.7 CTNNB1 MLH1

Graphical network of the top 20 diseases related to Atypical Polypoid Adenomyoma:



Diseases related to Atypical Polypoid Adenomyoma

Symptoms & Phenotypes for Atypical Polypoid Adenomyoma

MGI Mouse Phenotypes related to Atypical Polypoid Adenomyoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.35 CTNNB1 EMG1 MED12 MLH1 SATB2
2 embryo MP:0005380 8.92 CTNNB1 EMG1 MED12 SATB2

Drugs & Therapeutics for Atypical Polypoid Adenomyoma

Search Clinical Trials , NIH Clinical Center for Atypical Polypoid Adenomyoma

Genetic Tests for Atypical Polypoid Adenomyoma

Anatomical Context for Atypical Polypoid Adenomyoma

MalaCards organs/tissues related to Atypical Polypoid Adenomyoma:

42
Uterus, Ovary, Cervix

Publications for Atypical Polypoid Adenomyoma

Articles related to Atypical Polypoid Adenomyoma:

(show top 50) (show all 66)
# Title Authors Year
1
Atypical polypoid adenomyoma of the uterus: A reappraisal of the clinicopathological and immunohistochemical features. ( 30661903 )
2019
2
Management of women with atypical polypoid adenomyoma of the uterus: a quantitative systematic review. ( 30714089 )
2019
3
Hysteroscopic Transcervical Resection for Atypical Polypoid Adenomyoma of the Uterus: A Valid, Fertility-Preserving Option. ( 29038039 )
2018
4
Maintenance hormonal therapy after treatment with medroxyprogesterone acetate for patients with atypical polypoid adenomyoma. ( 29351618 )
2018
5
A case of rapidly-growing atypical polypoid adenomyoma which was histologically diagnosed before operation and removed by a laparoscopic resection. ( 29458879 )
2018
6
Management of atypical polypoid adenomyoma of the uterus: A single center's experience. ( 29561413 )
2018
7
Pregnant outcomes of atypical polypoid adenomyoma treated with progestin therapy. ( 29121416 )
2018
8
Cytomorphological features of atypical polypoid adenomyoma of the endometrium. ( 30556192 )
2018
9
SATB2 is Consistently Expressed in Squamous Morules Associated With Endometrioid Proliferative Lesions and in the Stroma of Atypical Polypoid Adenomyoma. ( 30085940 )
2018
10
Successful laparotomy tumor resection and levonorgestrel-releasing intrauterine system for atypical polypoid adenomyoma. ( 30094884 )
2018
11
Cytological features of atypical polypoid adenomyoma of the endometrium: A case report with literature review. ( 28160434 )
2017
12
Recurrent atypical polypoid adenomyoma and pregnancy: A new conservative approach with levonorgestrel-releasing intrauterine system. ( 28761925 )
2017
13
Positron Emission Tomography Findings in Atypical Polypoid Adenomyoma. ( 27134711 )
2016
14
A mixed carcinoma of the uterus arising from an atypical polypoid adenomyoma: a case report. ( 29943938 )
2016
15
Endocervical Atypical Polypoid Adenomyoma. ( 26304721 )
2015
16
Long-term outcomes of fertility-sparing treatment of atypical polypoid adenomyoma with medroxyprogesterone acetate. ( 26209972 )
2015
17
Atypical Polypoid Adenomyoma of the Uterus: An Immunohistochemical and Molecular Study of 21 Cases. ( 25828387 )
2015
18
A case of endometrioid adenocarcinoma developing 8A years after conservative management for atypical polypoid adenomyoma. ( 24707458 )
2014
19
Coexistence of endometrioid adenocarcinoma in atypical polypoid adenomyoma. ( 25612673 )
2014
20
Magnetic Resonance Imaging Findings in Atypical Polypoid Adenomyoma. ( 25286280 )
2014
21
Frequent I^-catenin gene mutations in atypical polypoid adenomyoma of the uterus. ( 24182564 )
2014
22
Hysteroscopic transcervical resection is useful to diagnose myometrial invasion in atypical polypoid adenomyoma coexisting with atypical endometrial hyperplasia or endometrial cancer with suspicious myometrial invasion. ( 25491392 )
2014
23
Clinical management of atypical polypoid adenomyoma of the uterus. A clinicopathological review of 29 cases. ( 23290989 )
2013
24
Atypical polypoid adenomyoma mixed with endometrioid carcinoma: a case report. ( 23590013 )
2013
25
A multiple perspectives on atypical polypoid adenomyoma of uterus. ( 23527553 )
2013
26
Multiple atypical polypoid adenomyoma of the uterus. ( 22684616 )
2012
27
Atypical polypoid adenomyoma of the uterus. A case report and a review of the literature. ( 22439420 )
2012
28
Coexisting atypical polypoid adenomyoma and endometrioid endometrial carcinoma in a young woman with Cowden Syndrome: Case report and implications for screening and prevention. ( 24371612 )
2012
29
Immunohistochemical characteristics of atypical polypoid adenomyoma with special reference to h-caldesmon. ( 21131830 )
2011
30
Complete hysteroscopic resection of a large atypical polypoid adenomyoma, followed by a successful pregnancy. ( 21530963 )
2011
31
Case of atypical polypoid adenomyoma that possibly underwent a serial progression from endometrial hyperplasia to carcinoma. ( 21272150 )
2011
32
Atypical polypoid adenomyoma of the uterus: an immunohistochemical study on 5 cases. ( 21684185 )
2011
33
Coexistent atypical polypoid adenomyoma and complex atypical endometrial hyperplasia in the uterus. ( 19950396 )
2010
34
Atypical polypoid adenomyoma. ( 20455738 )
2010
35
Incidental diagnosis of atypical polypoid adenomyoma in a young infertile woman. ( 20099510 )
2009
36
Successful pregnancy after four-step hysteroscopic technique for the treatment of atypical polypoid adenomyoma. ( 18371960 )
2008
37
Hysteroscopic treatment of atypical polypoid adenomyoma diagnosed incidentally in a young infertile woman. ( 17706212 )
2008
38
CD10 immunostaining distinguishes atypical polypoid adenomyofibroma (atypical polypoid adenomyoma) from endometrial carcinoma invading the myometrium. ( 18619643 )
2008
39
A case of endometrial carcinoma arising in a 36-year-old woman with uterine atypical polypoid adenomyoma (APA). ( 18592801 )
2008
40
Pregnancy outcome of a patient with atypical polypoid adenomyoma. ( 17482169 )
2007
41
Atypical polypoid adenomyoma of the uterus: appearance on (18)F-FDG PET/MRI fused images. ( 16423933 )
2006
42
Atypical polypoid adenomyoma: a systematic review of the English literature. ( 16623790 )
2006
43
Atypical polypoid adenomyoma and hysteroscopic endometrial ablation. ( 12970811 )
2003
44
MA1llerian tumor (atypical polypoid adenomyoma) with sex-cord differentiation arising from the oviduct in an adolescent cynomolgus monkey (Macaca fascicularis). ( 12696577 )
2003
45
Cytologic features of atypical polypoid adenomyoma of the endometrium. A case report. ( 12685203 )
2003
46
Atypical polypoid adenomyoma of the uterine cervix: a diagnostic problem. ( 12918485 )
2003
47
Molecular pathology of atypical polypoid adenomyoma of the uterus. ( 14506639 )
2003
48
Atypical polypoid adenomyoma mimicking cervical adenocarcinoma. ( 17050990 )
2002
49
Atypical polypoid adenomyoma. ( 12072817 )
2002
50
Atypical polypoid adenomyoma in a patient with hyperprolactinemia. ( 11520375 )
2001

Variations for Atypical Polypoid Adenomyoma

Expression for Atypical Polypoid Adenomyoma

Search GEO for disease gene expression data for Atypical Polypoid Adenomyoma.

Pathways for Atypical Polypoid Adenomyoma

Pathways related to Atypical Polypoid Adenomyoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.22 CTNNB1 MED12
2 10.85 CTNNB1 MED12
3 10.49 CTNNB1 MME

GO Terms for Atypical Polypoid Adenomyoma

Cellular components related to Atypical Polypoid Adenomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nucleoplasm GO:0005654 9.02 CTNNB1 EMG1 MED12 MLH1 SATB2

Biological processes related to Atypical Polypoid Adenomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 kidney development GO:0001822 9.37 CTNNB1 MME
2 neuron migration GO:0001764 9.32 CTNNB1 SATB2
3 canonical Wnt signaling pathway GO:0060070 9.26 CTNNB1 MED12
4 stem cell population maintenance GO:0019827 9.16 CTNNB1 MED12
5 androgen receptor signaling pathway GO:0030521 8.96 CTNNB1 MED12
6 embryonic brain development GO:1990403 8.62 CTNNB1 MED12

Molecular functions related to Atypical Polypoid Adenomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chromatin binding GO:0003682 8.92 CTNNB1 MED12 MLH1 SATB2

Sources for Atypical Polypoid Adenomyoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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