MCID: ATY009
MIFTS: 30

Atypical Polypoid Adenomyoma

Categories: Cancer diseases, Muscle diseases

Aliases & Classifications for Atypical Polypoid Adenomyoma

MalaCards integrated aliases for Atypical Polypoid Adenomyoma:

Name: Atypical Polypoid Adenomyoma 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:4993
NCIt 50 C6895
SNOMED-CT 68 40293003
UMLS 73 C1300347

Summaries for Atypical Polypoid Adenomyoma

Disease Ontology : 12 An adenomyoma that is a biphasic polypoid lesion consisting of a myofibroblastic stromal component and an endometrial intraepithelial neoplasm.

MalaCards based summary : Atypical Polypoid Adenomyoma is related to adenomyoma and endometrial adenocarcinoma. An important gene associated with Atypical Polypoid Adenomyoma is MME (Membrane Metalloendopeptidase), and among its related pathways/superpathways are Thyroid hormone signaling pathway and Regulation of Wnt-mediated beta catenin signaling and target gene transcription. Affiliated tissues include uterus, ovary and cervix, and related phenotypes are cellular and digestive/alimentary

Wikipedia : 76 Atypical polypoid adenomyoma, abbreviated APA, is a rare uncommon benign tumour of the... more...

Related Diseases for Atypical Polypoid Adenomyoma

Diseases related to Atypical Polypoid Adenomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 36)
# Related Disease Score Top Affiliating Genes
1 adenomyoma 31.4 CTNNB1 MLH1 MME
2 endometrial adenocarcinoma 30.4 CTNNB1 MLH1
3 endometrial cancer 29.9 CTNNB1 MLH1 MME
4 uterine corpus atypical polypoid adenomyoma 12.7
5 cervical atypical polypoid adenomyoma 12.5
6 adenocarcinoma 10.5
7 psammomatous meningioma 10.1 CTNNB1 MME
8 ovarian cancer 1 10.1
9 hyperprolactinemia 10.1
10 cervical adenocarcinoma 10.1
11 endometrioid ovary carcinoma 10.1
12 cowden disease 10.1
13 carcinosarcoma 10.1 CTNNB1 MME
14 intestinal benign neoplasm 10.1 CTNNB1 MLH1
15 uterine carcinosarcoma 10.1 CTNNB1 MME
16 mismatch repair cancer syndrome 10.1 CTNNB1 MLH1
17 uterine anomalies 10.1 CTNNB1 MLH1
18 colorectal adenoma 10.1 CTNNB1 MLH1
19 cell type benign neoplasm 10.0 CTNNB1 MLH1
20 breast benign neoplasm 10.0 MED12 MME
21 thoracic benign neoplasm 10.0 MED12 MME
22 colonic disease 10.0 CTNNB1 MLH1
23 colorectal adenocarcinoma 10.0 CTNNB1 MLH1
24 breast fibroadenoma 10.0 MED12 MME
25 stomach disease 10.0 CTNNB1 MLH1
26 female reproductive system disease 10.0 CTNNB1 MLH1
27 reproductive system disease 10.0 CTNNB1 MLH1
28 intestinal disease 10.0 CTNNB1 MLH1
29 anus, imperforate 10.0 MED12 SATB2
30 gastrointestinal system cancer 10.0 CTNNB1 MLH1
31 leiomyoma 10.0 MED12 MME
32 endocrine gland cancer 10.0 CTNNB1 MLH1
33 familial adenomatous polyposis 10.0 CTNNB1 MLH1
34 gastrointestinal system disease 9.9 CTNNB1 MLH1
35 lynch syndrome 9.9 CTNNB1 MLH1
36 ulcerative colitis 9.8 CTNNB1 MLH1

Graphical network of the top 20 diseases related to Atypical Polypoid Adenomyoma:



Diseases related to Atypical Polypoid Adenomyoma

Symptoms & Phenotypes for Atypical Polypoid Adenomyoma

MGI Mouse Phenotypes related to Atypical Polypoid Adenomyoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.35 CTNNB1 EPM2A MED12 MLH1 SATB2
2 digestive/alimentary MP:0005381 8.92 CTNNB1 EPM2A MLH1 SATB2

Drugs & Therapeutics for Atypical Polypoid Adenomyoma

Search Clinical Trials , NIH Clinical Center for Atypical Polypoid Adenomyoma

Genetic Tests for Atypical Polypoid Adenomyoma

Anatomical Context for Atypical Polypoid Adenomyoma

MalaCards organs/tissues related to Atypical Polypoid Adenomyoma:

41
Uterus, Ovary, Cervix, Colon, Breast

Publications for Atypical Polypoid Adenomyoma

Articles related to Atypical Polypoid Adenomyoma:

(show top 50) (show all 64)
# Title Authors Year
1
Hysteroscopic Transcervical Resection for Atypical Polypoid Adenomyoma of the Uterus: A Valid, Fertility-Preserving Option. ( 29038039 )
2018
2
Maintenance hormonal therapy after treatment with medroxyprogesterone acetate for patients with atypical polypoid adenomyoma. ( 29351618 )
2018
3
A case of rapidly-growing atypical polypoid adenomyoma which was histologically diagnosed before operation and removed by a laparoscopic resection. ( 29458879 )
2018
4
Management of atypical polypoid adenomyoma of the uterus: A single center's experience. ( 29561413 )
2018
5
Pregnant outcomes of atypical polypoid adenomyoma treated with progestin therapy. ( 29121416 )
2018
6
SATB2 is Consistently Expressed in Squamous Morules Associated With Endometrioid Proliferative Lesions and in the Stroma of Atypical Polypoid Adenomyoma. ( 30085940 )
2018
7
Successful laparotomy tumor resection and levonorgestrel-releasing intrauterine system for atypical polypoid adenomyoma. ( 30094884 )
2018
8
Cytomorphological features of atypical polypoid adenomyoma of the endometrium. ( 30556192 )
2018
9
Cytological features of atypical polypoid adenomyoma of the endometrium: A case report with literature review. ( 28160434 )
2017
10
Recurrent atypical polypoid adenomyoma and pregnancy: A new conservative approach with levonorgestrel-releasing intrauterine system. ( 28761925 )
2017
11
Positron Emission Tomography Findings in Atypical Polypoid Adenomyoma. ( 27134711 )
2016
12
A mixed carcinoma of the uterus arising from an atypical polypoid adenomyoma: a case report. ( 29943938 )
2016
13
Endocervical Atypical Polypoid Adenomyoma. ( 26304721 )
2015
14
Long-term outcomes of fertility-sparing treatment of atypical polypoid adenomyoma with medroxyprogesterone acetate. ( 26209972 )
2015
15
Atypical Polypoid Adenomyoma of the Uterus: An Immunohistochemical and Molecular Study of 21 Cases. ( 25828387 )
2015
16
A case of endometrioid adenocarcinoma developing 8A years after conservative management for atypical polypoid adenomyoma. ( 24707458 )
2014
17
Coexistence of endometrioid adenocarcinoma in atypical polypoid adenomyoma. ( 25612673 )
2014
18
Magnetic Resonance Imaging Findings in Atypical Polypoid Adenomyoma. ( 25286280 )
2014
19
Frequent I^-catenin gene mutations in atypical polypoid adenomyoma of the uterus. ( 24182564 )
2014
20
Hysteroscopic transcervical resection is useful to diagnose myometrial invasion in atypical polypoid adenomyoma coexisting with atypical endometrial hyperplasia or endometrial cancer with suspicious myometrial invasion. ( 25491392 )
2014
21
Clinical management of atypical polypoid adenomyoma of the uterus. A clinicopathological review of 29 cases. ( 23290989 )
2013
22
Atypical polypoid adenomyoma mixed with endometrioid carcinoma: a case report. ( 23590013 )
2013
23
A multiple perspectives on atypical polypoid adenomyoma of uterus. ( 23527553 )
2013
24
Multiple atypical polypoid adenomyoma of the uterus. ( 22684616 )
2012
25
Atypical polypoid adenomyoma of the uterus. A case report and a review of the literature. ( 22439420 )
2012
26
Coexisting atypical polypoid adenomyoma and endometrioid endometrial carcinoma in a young woman with Cowden Syndrome: Case report and implications for screening and prevention. ( 24371612 )
2012
27
Immunohistochemical characteristics of atypical polypoid adenomyoma with special reference to h-caldesmon. ( 21131830 )
2011
28
Complete hysteroscopic resection of a large atypical polypoid adenomyoma, followed by a successful pregnancy. ( 21530963 )
2011
29
Case of atypical polypoid adenomyoma that possibly underwent a serial progression from endometrial hyperplasia to carcinoma. ( 21272150 )
2011
30
Atypical polypoid adenomyoma of the uterus: an immunohistochemical study on 5 cases. ( 21684185 )
2011
31
Coexistent atypical polypoid adenomyoma and complex atypical endometrial hyperplasia in the uterus. ( 19950396 )
2010
32
Atypical polypoid adenomyoma. ( 20455738 )
2010
33
Incidental diagnosis of atypical polypoid adenomyoma in a young infertile woman. ( 20099510 )
2009
34
Successful pregnancy after four-step hysteroscopic technique for the treatment of atypical polypoid adenomyoma. ( 18371960 )
2008
35
Hysteroscopic treatment of atypical polypoid adenomyoma diagnosed incidentally in a young infertile woman. ( 17706212 )
2008
36
CD10 immunostaining distinguishes atypical polypoid adenomyofibroma (atypical polypoid adenomyoma) from endometrial carcinoma invading the myometrium. ( 18619643 )
2008
37
A case of endometrial carcinoma arising in a 36-year-old woman with uterine atypical polypoid adenomyoma (APA). ( 18592801 )
2008
38
Pregnancy outcome of a patient with atypical polypoid adenomyoma. ( 17482169 )
2007
39
Atypical polypoid adenomyoma of the uterus: appearance on (18)F-FDG PET/MRI fused images. ( 16423933 )
2006
40
Atypical polypoid adenomyoma: a systematic review of the English literature. ( 16623790 )
2006
41
Atypical polypoid adenomyoma and hysteroscopic endometrial ablation. ( 12970811 )
2003
42
MA1llerian tumor (atypical polypoid adenomyoma) with sex-cord differentiation arising from the oviduct in an adolescent cynomolgus monkey (Macaca fascicularis). ( 12696577 )
2003
43
Cytologic features of atypical polypoid adenomyoma of the endometrium. A case report. ( 12685203 )
2003
44
Atypical polypoid adenomyoma of the uterine cervix: a diagnostic problem. ( 12918485 )
2003
45
Molecular pathology of atypical polypoid adenomyoma of the uterus. ( 14506639 )
2003
46
Atypical polypoid adenomyoma mimicking cervical adenocarcinoma. ( 17050990 )
2002
47
Atypical polypoid adenomyoma. ( 12072817 )
2002
48
Atypical polypoid adenomyoma in a patient with hyperprolactinemia. ( 11520375 )
2001
49
Exfoliative cytology of atypical polypoid adenomyoma. A case report. ( 10432887 )
1999
50
Two cases of endometrial adenocarcinoma arising from atypical polypoid adenomyoma. ( 9784336 )
1998

Variations for Atypical Polypoid Adenomyoma

Expression for Atypical Polypoid Adenomyoma

Search GEO for disease gene expression data for Atypical Polypoid Adenomyoma.

Pathways for Atypical Polypoid Adenomyoma

Pathways related to Atypical Polypoid Adenomyoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.22 CTNNB1 MED12
2 10.85 CTNNB1 MED12
3 10.49 CTNNB1 MME

GO Terms for Atypical Polypoid Adenomyoma

Cellular components related to Atypical Polypoid Adenomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nucleoplasm GO:0005654 9.02 CTNNB1 EPM2A MED12 MLH1 SATB2

Biological processes related to Atypical Polypoid Adenomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 kidney development GO:0001822 9.37 CTNNB1 MME
2 neuron migration GO:0001764 9.32 CTNNB1 SATB2
3 canonical Wnt signaling pathway GO:0060070 9.26 CTNNB1 MED12
4 stem cell population maintenance GO:0019827 9.16 CTNNB1 MED12
5 androgen receptor signaling pathway GO:0030521 8.96 CTNNB1 MED12
6 embryonic brain development GO:1990403 8.62 CTNNB1 MED12

Molecular functions related to Atypical Polypoid Adenomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chromatin binding GO:0003682 8.92 CTNNB1 MED12 MLH1 SATB2

Sources for Atypical Polypoid Adenomyoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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