MCID: ADG002
MIFTS: 26

Audiogenic Seizures

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Audiogenic Seizures

MalaCards integrated aliases for Audiogenic Seizures:

Name: Audiogenic Seizures 60
Audiogenic Seizure 56 74

Classifications:

Orphanet: 60  
Rare neurological diseases


External Ids:

UMLS via Orphanet 75 C0751791
Orphanet 60 ORPHA166415
UMLS 74 C0596131

Summaries for Audiogenic Seizures

MalaCards based summary : Audiogenic Seizures, also known as audiogenic seizure, is related to epilepsy and seizure disorder. An important gene associated with Audiogenic Seizures is GIPC3 (GIPC PDZ Domain Containing Family Member 3). Affiliated tissues include brain, cortex and testes.

Related Diseases for Audiogenic Seizures

Diseases related to Audiogenic Seizures via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 31)
# Related Disease Score Top Affiliating Genes
1 epilepsy 10.8
2 seizure disorder 10.6
3 retinoblastoma 10.5
4 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.4
5 depression 10.4
6 ischemia 10.3
7 hearing loss, noise-induced 10.2
8 congenital hypothyroidism 10.2
9 cardiac arrest 10.2
10 hypothyroidism 10.2
11 pyridoxine deficiency 10.2
12 alzheimer disease 10.0
13 otitis media 10.0
14 down syndrome 10.0
15 sudden infant death syndrome 10.0
16 fragile x syndrome 10.0
17 aicardi syndrome 10.0
18 deafness, autosomal recessive 15 10.0
19 anxiety 10.0
20 sensorineural hearing loss 10.0
21 status epilepticus 10.0
22 focal epilepsy 10.0
23 middle ear disease 10.0
24 albinism 10.0
25 dwarfism 10.0
26 hyperacusis 10.0
27 hypoxia 10.0
28 tremor 10.0
29 febrile seizures 10.0
30 disease of mental health 9.6 FMR1 FOS
31 attention deficit-hyperactivity disorder 9.5 FMR1 FOS

Graphical network of the top 20 diseases related to Audiogenic Seizures:



Diseases related to Audiogenic Seizures

Symptoms & Phenotypes for Audiogenic Seizures

Drugs & Therapeutics for Audiogenic Seizures

Search Clinical Trials , NIH Clinical Center for Audiogenic Seizures

Genetic Tests for Audiogenic Seizures

Anatomical Context for Audiogenic Seizures

MalaCards organs/tissues related to Audiogenic Seizures:

42
Brain, Cortex, Testes, Amygdala, Thyroid, Adrenal Cortex, Cerebellum

Publications for Audiogenic Seizures

Articles related to Audiogenic Seizures:

(show top 50) (show all 593)
# Title Authors Year
1
Transcriptome of the Wistar audiogenic rat (WAR) strain following audiogenic seizures. ( 30193173 )
2018
2
Deletion of Long Isoform of Eukaryotic Elongation Factor 1Bδ Leads to Audiogenic Seizures and Aversive Stimulus-Induced Long-Lasting Activity Suppression in Mice. ( 30333725 )
2018
3
NEOCORTICAL IMPACT ON THE AUDIOGENIC SEIZURE ACTIVITY DEVELOPMENT. ( 30618407 )
2018
4
An abnormal GABAergic system in the inferior colliculus provides a basis for audiogenic seizures in genetically epilepsy-prone rats. ( 25812940 )
2017
5
Overexpression of the immediate-early genes Egr1, Egr2, and Egr3 in two strains of rodents susceptible to audiogenic seizures. ( 26775236 )
2017
6
A genetic context for the study of audiogenic seizures. ( 26907925 )
2017
7
Remote effects of short-term neonatal hyperthermia in Krushinsky-Molodkina rats prone to audiogenic seizures strain. ( 28429263 )
2017
8
Changes in the content of fatty acids in CA1 and CA3 areas of the hippocampus of Krushinsky-Molodkina rats after single and fivefold audiogenic seizures. ( 28692872 )
2017
9
Effects of ERK1/2 kinases inactivation on the nigrostriatal system of Krushinsky-Molodkina rats genetically prone to audiogenic seizures. ( 28738742 )
2017
10
Analysis of ERK1/2 kinases in the inferior colliculus of rats genetically prone to audiogenic seizures during postnatal development. ( 29101749 )
2017
11
Molecular and neurochemical substrates of the audiogenic seizure strains: The GASH:Sal model. ( 26071997 )
2017
12
Pharmacological and neuroethological study of the acute and chronic effects of lamotrigine in the genetic audiogenic seizure hamster (GASH:Sal). ( 26876275 )
2017
13
The genetic audiogenic seizure hamster from Salamanca: The GASH:Sal. ( 27072920 )
2017
14
Morphofunctional alterations in the olivocochlear efferent system of the genetic audiogenic seizure-prone hamster GASH:Sal. ( 27492627 )
2017
15
Audiogenic seizure activity following HSV-1 GAD65 sense or antisense injection into inferior colliculus of Long-Evans rat. ( 27993512 )
2017
16
Genetic background contributes to the co-morbidity of anxiety and depression with audiogenic seizure propensity and responses to fluoxetine treatment. ( 28135595 )
2017
17
Going to WAR: using a rat model of audiogenic seizure to uncover potential links to ventilatory dysfunction in epilepsy. ( 28145010 )
2017
18
Developmental PCB Exposure Increases Audiogenic Seizures and Decreases Glutamic Acid Decarboxylase in the Inferior Colliculus. ( 26543103 )
2016
19
Effect of Audiogenic Seizures on the Dynamics of Fatty Acid Composition of Hippocampal Dental Gyrus in Krushinsky-Molodkina Rats. ( 27383177 )
2016
20
Pharmacokinetic-pharmacodynamic influence of N-palmitoylethanolamine, arachidonyl-2'-chloroethylamide and WIN 55,212-2 on the anticonvulsant activity of antiepileptic drugs against audiogenic seizures in DBA/2 mice. ( 27663280 )
2016
21
Anticonvulsant effects of structurally diverse GABA(B) positive allosteric modulators in the DBA/2J audiogenic seizure test: Comparison to baclofen and utility as a pharmacodynamic screening model. ( 26471422 )
2016
22
Elevated ERK/p90 ribosomal S6 kinase activity underlies audiogenic seizure susceptibility in fragile X mice. ( 27663742 )
2016
23
Inhibition of ERK1/2 signaling prevents epileptiform behavior in rats prone to audiogenic seizures. ( 25351927 )
2015
24
Developmental PCB exposure increases susceptibility to audiogenic seizures in adulthood. ( 25543072 )
2015
25
Wistar Audiogenic Rats (WAR) exhibit altered levels of cytokines and brain-derived neurotrophic factor following audiogenic seizures. ( 25936592 )
2015
26
Antagonists of Metabotropic Glutamate Receptors Prevent the Development of Audiogenic Seizures. ( 26033576 )
2015
27
Occurrence of spontaneous and audiogenic seizures following global brain ischaemia due to cardiac arrest. ( 26443315 )
2015
28
The expression and distribution of seizure-related and synaptic proteins in the insular cortex of rats genetically prone to audiogenic seizures. ( 26923581 )
2015
29
Mice lacking selenoprotein P and selenocysteine lyase exhibit severe neurological dysfunction, neurodegeneration, and audiogenic seizures. ( 24519931 )
2014
30
Audiogenic seizure proneness after methyl-enriched diet in ontogeny. ( 24659292 )
2014
31
Amiloride and SN-6 suppress audiogenic seizure susceptibility in genetically epilepsy-prone rats. ( 24948133 )
2014
32
Maternal methyl-enriched diet in rat reduced the audiogenic seizure proneness in progeny. ( 25285618 )
2014
33
Pharmacodynamic potentiation of antiepileptic drugs' effects by some HMG-CoA reductase inhibitors against audiogenic seizures in DBA/2 mice. ( 23253428 )
2013
34
Resilience to audiogenic seizures is associated with p-ERK1/2 dephosphorylation in the subiculum of Fmr1 knockout mice. ( 23630463 )
2013
35
EEG characterization of audiogenic seizures in the hamster strain GASH:Sal. ( 23916142 )
2013
36
Improved technique for induction and monitoring of audiogenic seizure in deer mice. ( 23604158 )
2013
37
Pharmacological and neuroethological studies of three antiepileptic drugs in the Genetic Audiogenic Seizure Hamster (GASH:Sal). ( 23872084 )
2013
38
Fosinopril and zofenopril, two angiotensin-converting enzyme (ACE) inhibitors, potentiate the anticonvulsant activity of antiepileptic drugs against audiogenic seizures in DBA/2 mice. ( 22107891 )
2012
39
Anticonvulsant and antiarrhythmic effects of nifedipine in rats prone to audiogenic seizures. ( 22801414 )
2012
40
Binding of specific ligand by D2- and NMDA-receptors of striatum cells in two rat strains predisposed and resistant to audiogenic seizures. ( 23330123 )
2012
41
Gipc3 mutations associated with audiogenic seizures and sensorineural hearing loss in mouse and human. ( 21326233 )
2011
42
Post-ictal analgesia in genetically epilepsy-prone rats is induced by audiogenic seizures and involves cannabinoid receptors in the periaqueductal gray. ( 21439272 )
2011
43
Early age conductive hearing loss causes audiogenic seizure and hyperacusis behavior. ( 21872651 )
2011
44
Audiogenic seizure proneness requires the contribution of two susceptibility loci in mice. ( 21681693 )
2011
45
Non-convulsive status epilepticus and audiogenic seizures complicating a patient with asymmetrical epileptic spasms. ( 19735986 )
2010
46
Elevated sulfatide levels in neurons cause lethal audiogenic seizures in mice. ( 19860853 )
2010
47
DBA/1 mice exhibit chronic susceptibility to audiogenic seizures followed by sudden death associated with respiratory arrest. ( 20335075 )
2010
48
Alzheimer's disease and Down syndrome rodent models exhibit audiogenic seizures. ( 20413855 )
2010
49
Inhibition of adenylyl cyclase in amygdala blocks the effect of audiogenic seizure kindling in genetically epilepsy-prone rats. ( 20417219 )
2010
50
Deficiency of Vlgr1 resulted in deafness and susceptibility to audiogenic seizures while the degree of hearing impairment was not correlated with seizure severity in C57BL/6- and 129-backcrossed lines of Vlgr1 knockout mice. ( 19539720 )
2009

Variations for Audiogenic Seizures

Expression for Audiogenic Seizures

Search GEO for disease gene expression data for Audiogenic Seizures.

Pathways for Audiogenic Seizures

GO Terms for Audiogenic Seizures

Cellular components related to Audiogenic Seizures according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuron projection GO:0043005 8.62 FMR1 FOS

Biological processes related to Audiogenic Seizures according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nervous system development GO:0007399 8.62 FMR1 FOS

Molecular functions related to Audiogenic Seizures according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein heterodimerization activity GO:0046982 8.96 FMR1 FOS
2 chromatin binding GO:0003682 8.62 FMR1 FOS

Sources for Audiogenic Seizures

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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