MCID: ADT002
MIFTS: 24

Auditory System Cancer

Categories: Cancer diseases, Ear diseases, Neuronal diseases

Aliases & Classifications for Auditory System Cancer

MalaCards integrated aliases for Auditory System Cancer:

Name: Auditory System Cancer 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:833
MeSH 44 D004428
NCIt 50 C3000
UMLS 73 C0013449

Summaries for Auditory System Cancer

Disease Ontology : 12 An organ system cancer located in the ear and characterized by uncontrolled cellular proliferation of the auditory organs.

MalaCards based summary : Auditory System Cancer is related to intracranial primitive neuroectodermal tumor and somatostatinoma. An important gene associated with Auditory System Cancer is CHGA (Chromogranin A). Affiliated tissues include lung, kidney and bone, and related phenotypes are Decreased melanin production and nervous system

Related Diseases for Auditory System Cancer

Diseases related to Auditory System Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 152)
# Related Disease Score Top Affiliating Genes
1 intracranial primitive neuroectodermal tumor 10.1 CHGA ENO2
2 somatostatinoma 10.1 CHGA ENO2
3 epithelioid malignant peripheral nerve sheath tumor 10.1 CHGA ENO2
4 lung oat cell carcinoma 10.1 CHGA ENO2
5 goblet cell carcinoid 10.1 CHGA ENO2
6 acute thyroiditis 10.1 CHGA ENO2
7 adrenocortical carcinoma, hereditary 10.1 CHGA SYP
8 duodenal gastrinoma 10.1 CHGA ENO2
9 ureter small cell carcinoma 10.1 CHGA SYP
10 esophageal neuroendocrine tumor 10.1 CHGA SYP
11 ovarian large-cell neuroendocrine carcinoma 10.1 CHGA SYP
12 adenoma of the pancreas 10.1 CHGA SYP
13 acinar cell cystadenocarcinoma 10.1 CHGA SYP
14 peritoneal serous adenocarcinoma 10.1 CHGA SYP
15 cellular ependymoma 10.1 CHGA SYP
16 spinal meningioma 10.1 CHGA ENO2
17 primary hepatic neuroendocrine carcinoma 10.1 CHGA SYP
18 spinal canal and spinal cord meningioma 10.1 CHGA ENO2
19 gastrointestinal neuroendocrine tumor 10.1 CHGA SYP
20 chordoid meningioma 10.1 CHGA SYP
21 diffuse pulmonary fibrosis 10.1 CHGA ENO2
22 olfactory groove meningioma 10.1 CHGA SYP
23 nervous system disease 10.1 ENO2 SYP
24 pancreatic serous cystadenoma 10.1 CHGA SYP
25 aceruloplasminemia 10.1 PDYN SYP
26 cystadenoma 10.1 CHGA SYP
27 conventional angiosarcoma 10.1 CHGA SYP
28 nervous system benign neoplasm 10.1 ENO2 SYP
29 ganglioneuroblastoma 10.1 ENO2 SYP
30 ependymoma 10.1 ENO2 SYP
31 pulmonary sclerosing hemangioma 10.1 CHGA SYP
32 sclerosing hemangioma 10.1 CHGA SYP
33 carotid body cancer 10.1 ENO2 SYP
34 pancreatoblastoma 10.1 CHGA SYP
35 malignant sertoli cell tumor 10.1 ENO2 SYP
36 anterior cranial fossa meningioma 10.1 CHGA SYP
37 sinonasal undifferentiated carcinoma 10.1 ENO2 SYP
38 pancreatic somatostatinoma 10.1 ENO2 SYP
39 cutaneous ganglioneuroma 10.1 ENO2 SYP
40 extrahepatic bile duct adenocarcinoma 10.1 ENO2 SYP
41 papillary tumor of the pineal region 10.1 ENO2 SYP
42 pulmonary blastoma 10.1 CHGA SYP
43 orbital cancer 10.1 ENO2 SYP
44 pleomorphic xanthoastrocytoma 10.1 CHGA SYP
45 middle ear adenoma 10.1 ENO2 SYP
46 tanycytic ependymoma 10.1 CHGA SYP
47 non-functioning pancreatic endocrine tumor 10.1 CHGA SYP
48 central nervous system primitive neuroectodermal neoplasm 10.1 ENO2 SYP
49 cerebellum cancer 10.1 ENO2 SYP
50 clear cell ependymoma 10.1 ENO2 SYP

Graphical network of the top 20 diseases related to Auditory System Cancer:



Diseases related to Auditory System Cancer

Symptoms & Phenotypes for Auditory System Cancer

GenomeRNAi Phenotypes related to Auditory System Cancer according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased melanin production GR00056-A 8.62 ENO2 LYZ

MGI Mouse Phenotypes related to Auditory System Cancer:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 9.02 CHGA ENO2 LYZ PDYN SYP

Drugs & Therapeutics for Auditory System Cancer

Search Clinical Trials , NIH Clinical Center for Auditory System Cancer

Genetic Tests for Auditory System Cancer

Anatomical Context for Auditory System Cancer

MalaCards organs/tissues related to Auditory System Cancer:

41
Lung, Kidney, Bone, Spinal Cord, Thyroid, Pineal, Cerebellum

The Foundational Model of Anatomy Ontology organs/tissues related to Auditory System Cancer:

19
The Ear

Publications for Auditory System Cancer

Variations for Auditory System Cancer

Expression for Auditory System Cancer

Search GEO for disease gene expression data for Auditory System Cancer.

Pathways for Auditory System Cancer

GO Terms for Auditory System Cancer

Biological processes related to Auditory System Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 defense response to Gram-positive bacterium GO:0050830 9.26 CHGA LYZ
2 defense response to Gram-negative bacterium GO:0050829 9.16 CHGA LYZ
3 antimicrobial humoral response GO:0019730 8.96 CHGA LYZ
4 killing of cells of other organism GO:0031640 8.62 CHGA LYZ

Sources for Auditory System Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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