Aliases & Classifications for Australia Antigen

MalaCards integrated aliases for Australia Antigen:

Name: Australia Antigen 56

Characteristics:

OMIM:

56
Inheritance:
autosomal recessive vs. multifactorial


HPO:

31

External Ids:

OMIM 56 209800
MedGen 41 C0019168

Summaries for Australia Antigen

MalaCards based summary : Australia Antigen is related to viral hepatitis and hepatitis. The drugs Peginterferon alfa-2a and Antiviral Agents have been mentioned in the context of this disorder. Affiliated tissues include liver, testes and kidney, and related phenotypes are global developmental delay and autism

Wikipedia : 74 HBsAg (also known as the Australia antigen) is the surface antigen of the hepatitis B virus (HBV). It... more...

More information from OMIM: 209800

Related Diseases for Australia Antigen

Graphical network of the top 20 diseases related to Australia Antigen:



Diseases related to Australia Antigen

Symptoms & Phenotypes for Australia Antigen

Human phenotypes related to Australia Antigen:

31
# Description HPO Frequency HPO Source Accession
1 global developmental delay 31 HP:0001263
2 autism 31 HP:0000717

Symptoms via clinical synopsis from OMIM:

56
Neuro:
autism
social, language, and cognitive development impaired

Clinical features from OMIM:

209800

Drugs & Therapeutics for Australia Antigen

Drugs for Australia Antigen (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Peginterferon alfa-2a Approved, Investigational 198153-51-4 5360545
2 Antiviral Agents
3 Immunologic Factors
4 Interferon alpha-2
5 interferons
6 Anti-Infective Agents
7 Interferon-alpha

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Observation Study of Different Optimized Therapy Method of Patients With Chronic Hepatitis B Completed NCT01623778 Interferon Alfa-2a add on ADV

Search NIH Clinical Center for Australia Antigen

Genetic Tests for Australia Antigen

Anatomical Context for Australia Antigen

MalaCards organs/tissues related to Australia Antigen:

40
Liver, Testes, Kidney, Skin, Bone, Smooth Muscle, Bone Marrow

Publications for Australia Antigen

Articles related to Australia Antigen:

(show top 50) (show all 1553)
# Title Authors PMID Year
1
Australia antigen as a hepatitis virus. Variation in host response. 61 56
4245144 1970
2
Australia antigen in acute and chronic liver disease. 61 56
4183241 1969
3
Hepatitis and Australia antigen: autosomal recessive inheritance of susceptibility to infection in humans. 61 56
4978906 1969
4
Australia antigen detected in the nuclei of liver cells of patients with viral hepatitis by the fluorescent antibody technic. 61 56
4975833 1969
5
Australia antigen and acute viral hepatitis. 61 56
4236725 1969
6
Particles associated with Australia antigen in the sera of patients with leukaemia, Down's Syndrome and hepatitis. 61 56
4231935 1968
7
Association between lepromatous leprosy and Australia antigen. 61 56
4165704 1967
8
Family studies of a human serum isoantigen system (Australia antigen). 61 56
4959134 1966
9
Further studies on a "new" human isoprecipitin system (Australia antigen). 61 56
5930797 1966
10
[The hypothesis of the genetic transmission (autosomal recessive) of subtypes of HBs Ag. The example of Kel Kummer]. 56
417847 1978
11
A "NEW" ANTIGEN IN LEUKEMIA SERA. 56
14239025 1965
12
An Immortalized Hepatocyte-like Cell Line (imHC) Accommodated Complete Viral Lifecycle, Viral Persistence Form, cccDNA and Eventual Spreading of a Clinically-Isolated HBV. 61
31623162 2019
13
History of the Discovery of Hepatitis A Virus. 61
29712682 2019
14
THE GORDON WILSON LECTURE: THE HEPATITIS C VIRUS: FROM HIPPOCRATES TO CURE. 61
31516174 2019
15
Risk Factors and Rates of Hepatitis B Virus Infection among Municipal Waste Management Workers and Scavengers in Ilorin, Kwara State, Nigeria. 61
30524799 2016
16
Nucleic acid polymers: Broad spectrum antiviral activity, antiviral mechanisms and optimization for the treatment of hepatitis B and hepatitis D infection. 61
27400989 2016
17
A historical perspective on the discovery and elucidation of the hepatitis B virus. 61
27107897 2016
18
Hepatitis B: 50 years after the discovery of Australia antigen. 61
26280668 2016
19
Targeting hepatitis B virus cccDNA using CRISPR/Cas9. 61
26476375 2015
20
Current status of immunomodulatory therapy in chronic hepatitis B, fifty years after discovery of the virus: Search for the "magic bullet" to kill cccDNA. 61
26476376 2015
21
A computational chemistry perspective on the current status and future direction of hepatitis B antiviral drug discovery. 61
26477294 2015
22
Hepatitis B virus reverse transcriptase - Target of current antiviral therapy and future drug development. 61
26408354 2015
23
Hepatitis delta virus: From biological and medical aspects to current and investigational therapeutic options. 61
26275800 2015
24
Immune-modulators to combat hepatitis B virus infection: From IFN-α to novel investigational immunotherapeutic strategies. 61
26275801 2015
25
Metabolism and function of hepatitis B virus cccDNA: Implications for the development of cccDNA-targeting antiviral therapeutics. 61
26272257 2015
26
Chronic hepatitis B: A wave of new therapies on the horizon. 61
26112647 2015
27
NTCP opens the door for hepatitis B virus infection. 61
26071008 2015
28
Modeling hepatitis B virus infection, immunopathology and therapy in mice. 61
26099683 2015
29
Treatment of chronic hepatitis B with pattern recognition receptor agonists: Current status and potential for a cure. 61
26205674 2015
30
Core protein: A pleiotropic keystone in the HBV lifecycle. 61
26129969 2015
31
Synthetic RNAi triggers and their use in chronic hepatitis B therapies with curative intent. 61
26129970 2015
32
[Reactivation of Hepatitis B Virus and Guidelines for Its Prevention]. 61
26731892 2015
33
Chronic hepatitis B: Virology, natural history, current management and a glimpse at future opportunities. 61
26092643 2015
34
The hepatitis B virus ribonuclease H as a drug target. 61
25862291 2015
35
Medical virology of hepatitis B: how it began and where we are now. 61
23870415 2013
36
[Reverse genetics of Hepatitis B virus]. 61
24769574 2013
37
The end of the Australia antigen? An ecological study of the impact of universal newborn hepatitis B vaccination two decades on. 61
23036497 2012
38
Thalassemia Major in Adults: Short Stature, Hyperpigmentation, Inadequate Chelation, and Transfusion-Transmitted Infections are Key Features. 61
22454828 2012
39
Towards the eradication of hepatitis B in Taiwan. 61
22226055 2012
40
The Australia antigen and role of the late Philadelphia General Hospital in reducing post-transfusion hepatitis and sequelae. 61
21809361 2011
41
Science, Names Giving and Names Calling: Change NDM-1 to PCM. 61
21694981 2011
42
Current status of liver diseases in Korea: hepatitis B. 61
20037275 2009
43
Immunogenicity of low dose intradermal hepatitis B vaccine and its comparison with standard dose intramuscular vaccination. 61
15475635 2004
44
Hepatitis B: review of development from the discovery of the "Australia Antigen" to end of the twentieth Century. 61
16190102 2004
45
[Chronic hepatitis B virus infection]. 61
15381940 2004
46
The unexpected outcomes of medical research: serendipity and the Australia antigen. Blumberg BS, Alter HJ, Visnich S. A new antigen in leukemia sera [J Am Med Assoc 1965;191:541-546]. 61
12873809 2003
47
Treatment of chronic hepatitis B: case selection and duration of therapy. 61
11982721 2002
48
Long-term outcome of acute hepatitis B and C in an outbreak of hepatitis in 1969-72. 61
10706175 2000
49
A gastroenterological list for the millennium. 61
10599637 1999
50
An unusual massive head-neck tumor and its surgical management. 61
23119576 1999

Variations for Australia Antigen

Expression for Australia Antigen

Search GEO for disease gene expression data for Australia Antigen.

Pathways for Australia Antigen

GO Terms for Australia Antigen

Sources for Australia Antigen

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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