AUTS12
MCID: ATS374
MIFTS: 15

Autism 12 (AUTS12)

Categories: Eye diseases, Genetic diseases, Mental diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Autism 12

MalaCards integrated aliases for Autism 12:

Name: Autism 12 57
Autism Susceptibility 12 57 13
Autism, Susceptibility to, 12 57
Auts12 57

Classifications:



External Ids:

OMIM® 57 610838
OMIM Phenotypic Series 57 PS209850

Summaries for Autism 12

OMIM® : 57 Autism, the prototypic pervasive developmental disorder (PDD), is usually apparent by 3 years of age. It is characterized by a triad of limited or absent verbal communication, a lack of reciprocal social interaction or responsiveness, and restricted, stereotypic, and ritualized patterns of interests and behavior (Bailey et al., 1996; Risch et al., 1999). 'Autism spectrum disorder,' sometimes referred to as ASD, is a broader phenotype encompassing the less severe disorders Asperger syndrome (see ASPG1; 608638) and pervasive developmental disorder, not otherwise specified (PDD-NOS). 'Broad autism phenotype' includes individuals with some symptoms of autism, but who do not meet the full criteria for autism or other disorders. Mental retardation coexists in approximately two-thirds of individuals with ASD, except for Asperger syndrome, in which mental retardation is conspicuously absent (Jones et al., 2008). Genetic studies in autism often include family members with these less stringent diagnoses (Schellenberg et al., 2006). For a discussion of genetic heterogeneity of autism, see 209850. (610838) (Updated 05-Apr-2021)

MalaCards based summary : Autism 12, also known as autism susceptibility 12, is related to autism. An important gene associated with Autism 12 is AUTS12 (Autism, Susceptibility To, 12). Affiliated tissues include amygdala.

Related Diseases for Autism 12

Diseases in the Autism family:

Autism 8 Autism 3
Autism 6 Autism 7
Autism 11 Autism 12
Autism 13 Autism 9
Autism 10 Autism 15
Autism 16 Autism 17
Autism 18 Autism 19
Autism 20 Autism Spectrum Disorder
Rare Disease with Autism

Diseases related to Autism 12 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 autism 9.8

Symptoms & Phenotypes for Autism 12

Clinical features from OMIM®:

610838 (Updated 05-Apr-2021)

Drugs & Therapeutics for Autism 12

Search Clinical Trials , NIH Clinical Center for Autism 12

Genetic Tests for Autism 12

Anatomical Context for Autism 12

MalaCards organs/tissues related to Autism 12:

40
Amygdala

Publications for Autism 12

Articles related to Autism 12:

(show all 15)
# Title Authors PMID Year
1
Hypothesis: dysregulation of methylation of brain-expressed genes on the X chromosome and autism spectrum disorders. 57
18698615 2008
2
Evidence for multiple loci from a genome scan of autism kindreds. 57
16880825 2006
3
Evidence for linkage on 21q and 7q in a subset of autism characterized by developmental regression. 57
15940295 2005
4
A genomic screen of autism: evidence for a multilocus etiology. 57
10417292 1999
5
Autism: towards an integration of clinical, genetic, neuropsychological, and neurobiological perspectives. 57
8655659 1996
6
Complementary and alternative medicine use in adults with autism spectrum disorder in Germany: results from a multi-center survey. 61
30709386 2019
7
Characteristics and Associated Comorbidities of Pediatric Dental Patients Treated under General Anesthesia. 61
28937887 2017
8
[Schooling of patients exhibiting Autism Spectrum Disorders without mental retardation]. 61
26358485 2015
9
Changing patterns of alpha agonist medication use in children and adolescents 2009-2011. 61
25919708 2015
10
Preschool-based social communication treatment for children with autism: 12-month follow-up of a randomized trial. 61
24472253 2014
11
Amygdala and hippocampus enlargement during adolescence in autism. 61
20494265 2010
12
Big heads, small details and autism. 61
19428391 2009
13
[Various central nervous system involvements in dystrophinopathy: clinical and genetic considerations]. 61
18210857 2008
14
Effects of age on brain volume and head circumference in autism. 61
12136053 2002
15
Untoward effects of fenfluramine in autistic children. 61
3543069 1986

Variations for Autism 12

Expression for Autism 12

Search GEO for disease gene expression data for Autism 12.

Pathways for Autism 12

GO Terms for Autism 12

Sources for Autism 12

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....