MCID: ATM103
MIFTS: 19

Autoimmune Atherosclerosis

Categories: Cardiovascular diseases, Immune diseases

Aliases & Classifications for Autoimmune Atherosclerosis

MalaCards integrated aliases for Autoimmune Atherosclerosis:

Name: Autoimmune Atherosclerosis 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0040096

Summaries for Autoimmune Atherosclerosis

Disease Ontology : 12 An autoimmune disease of cardiovascular system that is characterized by a build up of plaque in the arteries.

MalaCards based summary : Autoimmune Atherosclerosis is related to bacillary angiomatosis and opportunistic bacterial infectious disease. An important gene associated with Autoimmune Atherosclerosis is HSPD1 (Heat Shock Protein Family D (Hsp60) Member 1), and among its related pathways/superpathways are IgA-Producing B Cells in the Intestine and Th2 Differentiation Pathway.

Related Diseases for Autoimmune Atherosclerosis

Diseases related to Autoimmune Atherosclerosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 93)
# Related Disease Score Top Affiliating Genes
1 bacillary angiomatosis 10.2 HSPD1 CD4
2 opportunistic bacterial infectious disease 10.2 HSPD1 CD4
3 nocardiosis 10.2 HSPD1 CD4
4 chancroid 10.2 HSPD1 CD4
5 glanders 10.2 HSPD1 CD4
6 cat-scratch disease 10.2 HSPD1 CD4
7 tenosynovitis 10.2 HSPD1 CD4
8 cervical adenitis 10.2 HSPD1 CD4
9 bartonellosis 10.2 HSPD1 CD4
10 whipple disease 10.2 HSPD1 CD4
11 adiaspiromycosis 10.1 HSPD1 CD4
12 salpingitis 10.1 HSPD1 CD4
13 erythema infectiosum 10.1 CD4 APOH
14 chlamydia pneumonia 10.1 HSPD1 CD4
15 cerebritis 10.1 CD4 APOH
16 viral exanthem 10.1 CD4 APOH
17 tick infestation 10.1 HSPD1 CD4
18 inclusion body myopathy with early-onset paget disease of bone with or without frontotemporal dementia 2 10.1 HSPD1 CD4
19 urethritis 10.1 HSPD1 CD4
20 syphilitic meningitis 10.1 CD4 APOH
21 macs syndrome 10.1 HSPD1 CD4
22 primary systemic mycosis 10.1 HSPD1 CD4
23 multidrug-resistant tuberculosis 10.1 HSPD1 CD4
24 cervicitis 10.1 HSPD1 CD4
25 tularemia 10.1 HSPD1 CD4
26 subcutaneous mycosis 10.1 CLEC1A CD4
27 mixed connective tissue disease 10.1 HSPD1 APOH
28 papilledema 10.1 CD4 APOH
29 retinal vasculitis 10.1 CD4 APOH
30 ehrlichiosis 10.1 HSPD1 CD4
31 endocardium disease 10.1 HSPD1 CD4
32 pontocerebellar hypoplasia, type 2a 10.1 HSPD1 HSPA14
33 caplan's syndrome 10.1 FOXP3 CD4
34 autoimmune disease of cardiovascular system 10.1 CD4 APOH
35 autoimmune neuropathy 10.1 FOXP3 CD4
36 dacryoadenitis 10.1 FOXP3 CD4
37 immunodeficiency 41 with lymphoproliferation and autoimmunity 10.0 FOXP3 CD4
38 orchitis 10.0 FOXP3 CD4
39 atherosclerosis susceptibility 10.0
40 filarial elephantiasis 10.0 FOXP3 CD4
41 legume allergy 10.0 FOXP3 CD4
42 fruit allergy 10.0 FOXP3 CD4
43 t-cell adult acute lymphocytic leukemia 10.0 FOXP3 CD4
44 autoimmune disease of eyes, ear, nose and throat 10.0 FOXP3 CD4
45 commensal bacterial infectious disease 10.0 HSPD1 CD4
46 primary thrombocytopenia 10.0 FOXP3 CD4
47 hypersplenism 10.0 FOXP3 CD4
48 autoimmune disease of blood 10.0 FOXP3 CD4
49 immunodysregulation, polyendocrinopathy, and enteropathy, x-linked 10.0 FOXP3 CD4
50 epidemic typhus 10.0 HSPD1 CD4

Graphical network of the top 20 diseases related to Autoimmune Atherosclerosis:



Diseases related to Autoimmune Atherosclerosis

Symptoms & Phenotypes for Autoimmune Atherosclerosis

Drugs & Therapeutics for Autoimmune Atherosclerosis

Search Clinical Trials , NIH Clinical Center for Autoimmune Atherosclerosis

Genetic Tests for Autoimmune Atherosclerosis

Anatomical Context for Autoimmune Atherosclerosis

Publications for Autoimmune Atherosclerosis

Articles related to Autoimmune Atherosclerosis:

# Title Authors PMID Year
1
Autoimmune and angiogenic biomarkers in autoimmune atherosclerosis. 61
30543922 2019
2
Autoimmune atherosclerosis in 3D: How it develops, how to diagnose and what to do. 61
26979271 2016
3
Is atherosclerosis an autoimmune disease? 61
24642015 2014
4
Aspirin may do wonders by the induction of immunological self-tolerance against autoimmune atherosclerosis. 61
22070887 2012
5
Identification of immunoreactive epitopes of the Porphyromonas gingivalis heat shock protein in periodontitis and atherosclerosis. 61
21241301 2011

Variations for Autoimmune Atherosclerosis

Expression for Autoimmune Atherosclerosis

Search GEO for disease gene expression data for Autoimmune Atherosclerosis.

Pathways for Autoimmune Atherosclerosis

Pathways related to Autoimmune Atherosclerosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.78 VCAM1 FOXP3
2 10.29 FOXP3 CD4

GO Terms for Autoimmune Atherosclerosis

Cellular components related to Autoimmune Atherosclerosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 early endosome GO:0005769 9.13 VCAM1 HSPD1 CD4
2 cell surface GO:0009986 8.92 VCAM1 HSPD1 CD4 APOH

Biological processes related to Autoimmune Atherosclerosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of T cell proliferation GO:0042102 9.32 VCAM1 CD4
2 positive regulation of T cell activation GO:0050870 9.26 HSPD1 CD4
3 protein refolding GO:0042026 9.16 HSPD1 HSPA14
4 response to lipopolysaccharide GO:0032496 9.13 VCAM1 HSPD1 FOXP3
5 T cell activation GO:0042110 8.8 HSPD1 FOXP3 CD4

Sources for Autoimmune Atherosclerosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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