Autoimmune Atherosclerosis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Autoimmune Atherosclerosis

MalaCards integrated aliases for Autoimmune Atherosclerosis:

Name: Autoimmune Atherosclerosis ¹² ¹⁵

Classifications:

MalaCards categories:
Anatomical: Cardiovascular diseases Immune diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:0040096

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Summaries for Autoimmune Atherosclerosis

Disease Ontology : ¹² An autoimmune disease of cardiovascular system that is characterized by a build up of plaque in the arteries.

MalaCards based summary : Autoimmune Atherosclerosis is related to bacillary angiomatosis and opportunistic bacterial infectious disease. An important gene associated with Autoimmune Atherosclerosis is HSPD1 (Heat Shock Protein Family D (Hsp60) Member 1), and among its related pathways/superpathways are IgA-Producing B Cells in the Intestine and Th2 Differentiation Pathway.

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Related Diseases for Autoimmune Atherosclerosis

Diseases related to Autoimmune Atherosclerosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 93)

#	Related Disease	Score	Top Affiliating Genes
1	bacillary angiomatosis	10.2	HSPD1 CD4
2	opportunistic bacterial infectious disease	10.2	HSPD1 CD4
3	nocardiosis	10.2	HSPD1 CD4
4	chancroid	10.2	HSPD1 CD4
5	glanders	10.2	HSPD1 CD4
6	cat-scratch disease	10.2	HSPD1 CD4
7	tenosynovitis	10.2	HSPD1 CD4
8	cervical adenitis	10.2	HSPD1 CD4
9	bartonellosis	10.2	HSPD1 CD4
10	whipple disease	10.2	HSPD1 CD4
11	adiaspiromycosis	10.1	HSPD1 CD4
12	salpingitis	10.1	HSPD1 CD4
13	erythema infectiosum	10.1	CD4 APOH
14	chlamydia pneumonia	10.1	HSPD1 CD4
15	cerebritis	10.1	CD4 APOH
16	viral exanthem	10.1	CD4 APOH
17	tick infestation	10.1	HSPD1 CD4
18	inclusion body myopathy with early-onset paget disease of bone with or without frontotemporal dementia 2	10.1	HSPD1 CD4
19	urethritis	10.1	HSPD1 CD4
20	syphilitic meningitis	10.1	CD4 APOH
21	macs syndrome	10.1	HSPD1 CD4
22	primary systemic mycosis	10.1	HSPD1 CD4
23	multidrug-resistant tuberculosis	10.1	HSPD1 CD4
24	cervicitis	10.1	HSPD1 CD4
25	tularemia	10.1	HSPD1 CD4
26	subcutaneous mycosis	10.1	CLEC1A CD4
27	mixed connective tissue disease	10.1	HSPD1 APOH
28	papilledema	10.1	CD4 APOH
29	retinal vasculitis	10.1	CD4 APOH
30	ehrlichiosis	10.1	HSPD1 CD4
31	endocardium disease	10.1	HSPD1 CD4
32	pontocerebellar hypoplasia, type 2a	10.1	HSPD1 HSPA14
33	caplan's syndrome	10.1	FOXP3 CD4
34	autoimmune disease of cardiovascular system	10.1	CD4 APOH
35	autoimmune neuropathy	10.1	FOXP3 CD4
36	dacryoadenitis	10.1	FOXP3 CD4
37	immunodeficiency 41 with lymphoproliferation and autoimmunity	10.0	FOXP3 CD4
38	orchitis	10.0	FOXP3 CD4
39	atherosclerosis susceptibility	10.0
40	filarial elephantiasis	10.0	FOXP3 CD4
41	legume allergy	10.0	FOXP3 CD4
42	fruit allergy	10.0	FOXP3 CD4
43	t-cell adult acute lymphocytic leukemia	10.0	FOXP3 CD4
44	autoimmune disease of eyes, ear, nose and throat	10.0	FOXP3 CD4
45	commensal bacterial infectious disease	10.0	HSPD1 CD4
46	primary thrombocytopenia	10.0	FOXP3 CD4
47	hypersplenism	10.0	FOXP3 CD4
48	autoimmune disease of blood	10.0	FOXP3 CD4
49	immunodysregulation, polyendocrinopathy, and enteropathy, x-linked	10.0	FOXP3 CD4
50	epidemic typhus	10.0	HSPD1 CD4

Graphical network of the top 20 diseases related to Autoimmune Atherosclerosis:

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Symptoms & Phenotypes for Autoimmune Atherosclerosis

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Drugs & Therapeutics for Autoimmune Atherosclerosis

Search Clinical Trials , NIH Clinical Center for Autoimmune Atherosclerosis

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Genetic Tests for Autoimmune Atherosclerosis

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Anatomical Context for Autoimmune Atherosclerosis

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Publications for Autoimmune Atherosclerosis

Articles related to Autoimmune Atherosclerosis:

#	Title	Authors	PMID	Year
1	Autoimmune and angiogenic biomarkers in autoimmune atherosclerosis. ⁶¹	Balogh E...Szekanecz Z	30543922	2019
2	Autoimmune atherosclerosis in 3D: How it develops, how to diagnose and what to do. ⁶¹	Szekanecz Z...Shoenfeld Y	26979271	2016
3	Is atherosclerosis an autoimmune disease? ⁶¹	Matsuura E...Nurmohamed MT	24642015	2014
4	Aspirin may do wonders by the induction of immunological self-tolerance against autoimmune atherosclerosis. ⁶¹	Hussain M...Mushtaq MH	22070887	2012
5	Identification of immunoreactive epitopes of the Porphyromonas gingivalis heat shock protein in periodontitis and atherosclerosis. ⁶¹	Choi J...Choi BK	21241301	2011

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Genes for Autoimmune Atherosclerosis

Genes related to Autoimmune Atherosclerosis (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	HSPD1	Heat Shock Protein Family D (Hsp60) Member 1	Protein Coding	6.19	DISEASES inferred ¹⁵
2	APOH	Apolipoprotein H	Protein Coding	4.91	DISEASES inferred ¹⁵
3	CLEC1A	C-Type Lectin Domain Family 1 Member A	Protein Coding	4.73	DISEASES inferred ¹⁵
4	NUDCD1	NudC Domain Containing 1	Protein Coding	4.66	DISEASES inferred ¹⁵
5	FOXP3	Forkhead Box P3	Protein Coding	4.25	DISEASES inferred ¹⁵
6	HSPA14	Heat Shock Protein Family A (Hsp70) Member 14	Protein Coding	4.21	DISEASES inferred ¹⁵
7	VCAM1	Vascular Cell Adhesion Molecule 1	Protein Coding	4.2	DISEASES inferred ¹⁵
8	CD4	CD4 Molecule	Protein Coding	4.04	DISEASES inferred ¹⁵

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Variations for Autoimmune Atherosclerosis

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Expression for Autoimmune Atherosclerosis

Search GEO for disease gene expression data for Autoimmune Atherosclerosis.

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Pathways for Autoimmune Atherosclerosis

Pathways related to Autoimmune Atherosclerosis according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	IgA-Producing B Cells in the Intestine ⁶⁴	10.78	VCAM1 FOXP3
2	Th2 Differentiation Pathway ⁶⁴	10.29	FOXP3 CD4

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GO Terms for Autoimmune Atherosclerosis

Cellular components related to Autoimmune Atherosclerosis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	early endosome	GO:0005769	9.13	VCAM1 HSPD1 CD4
2	cell surface	GO:0009986	8.92	VCAM1 HSPD1 CD4 APOH

Biological processes related to Autoimmune Atherosclerosis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of T cell proliferation	GO:0042102	9.32	VCAM1 CD4
2	positive regulation of T cell activation	GO:0050870	9.26	HSPD1 CD4
3	protein refolding	GO:0042026	9.16	HSPD1 HSPA14
4	response to lipopolysaccharide	GO:0032496	9.13	VCAM1 HSPD1 FOXP3
5	T cell activation	GO:0042110	8.8	HSPD1 FOXP3 CD4

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Sources for Autoimmune Atherosclerosis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GARD

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MedlinePlus Genetics

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 05-Mar-2021)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia