MCID: ATM103
MIFTS: 15

Autoimmune Atherosclerosis

Categories: Cardiovascular diseases, Immune diseases

Aliases & Classifications for Autoimmune Atherosclerosis

MalaCards integrated aliases for Autoimmune Atherosclerosis:

Name: Autoimmune Atherosclerosis 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0040096

Summaries for Autoimmune Atherosclerosis

Disease Ontology : 12 An autoimmune disease of cardiovascular system that is characterized by a build up of plaque in the arteries.

MalaCards based summary : Autoimmune Atherosclerosis is related to atherosclerosis susceptibility and alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity. An important gene associated with Autoimmune Atherosclerosis is HSPD1 (Heat Shock Protein Family D (Hsp60) Member 1).

Related Diseases for Autoimmune Atherosclerosis

Diseases related to Autoimmune Atherosclerosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 29)
# Related Disease Score Top Affiliating Genes
1 atherosclerosis susceptibility 29.8 VCAM1 LDLR HSPD1
2 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.2
3 mixed connective tissue disease 10.2 HSPD1 APOH
4 oral lichen planus 10.1 VCAM1 HSPD1
5 carotid artery occlusion 10.1 LDLR APOH
6 polyarteritis nodosa 10.0 VCAM1 APOH
7 trachoma 10.0 HSPD1 FOXP3
8 severe pre-eclampsia 10.0 VCAM1 APOH
9 lymph node disease 10.0 HSPD1 FOXP3
10 homocysteinemia 9.9 VCAM1 APOH
11 takayasu arteritis 9.9 VCAM1 APOH
12 leprosy 3 9.9 HSPD1 FOXP3
13 pontocerebellar hypoplasia, type 2a 9.9 HSPD1 HSPA14
14 antiphospholipid syndrome 9.9 VCAM1 APOH
15 endocarditis 9.8 VCAM1 HSPD1 APOH
16 vasculitis 9.8 VCAM1 HSPD1 APOH
17 autoimmune disease of musculoskeletal system 9.7 FOXP3 APOH
18 kawasaki disease 9.7 HSPD1 FOXP3
19 cerebrovascular disease 9.7 VCAM1 LDLR APOH
20 diabetes mellitus, type i 9.5 VCAM1 HSPD1 FOXP3
21 primary bacterial infectious disease 9.5 HSPD1 FOXP3
22 pre-eclampsia 9.5 VCAM1 FOXP3 APOH
23 vascular disease 9.4 VCAM1 LDLR HSPD1 APOH
24 behcet syndrome 9.4 VCAM1 HSPD1 FOXP3 APOH
25 autoimmune disease 9.3 VCAM1 HSPD1 FOXP3 APOH
26 rheumatoid arthritis 9.3 VCAM1 HSPD1 FOXP3 APOH
27 malaria 9.3 VCAM1 HSPD1 FOXP3 APOH
28 arteriosclerosis 9.3 VCAM1 LDLR HSPD1 FOXP3
29 diabetes mellitus 9.1 VCAM1 LDLR HSPD1 FOXP3

Graphical network of the top 20 diseases related to Autoimmune Atherosclerosis:



Diseases related to Autoimmune Atherosclerosis

Symptoms & Phenotypes for Autoimmune Atherosclerosis

Drugs & Therapeutics for Autoimmune Atherosclerosis

Search Clinical Trials , NIH Clinical Center for Autoimmune Atherosclerosis

Genetic Tests for Autoimmune Atherosclerosis

Anatomical Context for Autoimmune Atherosclerosis

Publications for Autoimmune Atherosclerosis

Articles related to Autoimmune Atherosclerosis:

# Title Authors PMID Year
1
Autoimmune and angiogenic biomarkers in autoimmune atherosclerosis. 61
30543922 2019
2
Autoimmune atherosclerosis in 3D: How it develops, how to diagnose and what to do. 61
26979271 2016
3
Is atherosclerosis an autoimmune disease? 61
24642015 2014
4
Aspirin may do wonders by the induction of immunological self-tolerance against autoimmune atherosclerosis. 61
22070887 2012
5
Identification of immunoreactive epitopes of the Porphyromonas gingivalis heat shock protein in periodontitis and atherosclerosis. 61
21241301 2011

Variations for Autoimmune Atherosclerosis

Expression for Autoimmune Atherosclerosis

Search GEO for disease gene expression data for Autoimmune Atherosclerosis.

Pathways for Autoimmune Atherosclerosis

GO Terms for Autoimmune Atherosclerosis

Cellular components related to Autoimmune Atherosclerosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 apical part of cell GO:0045177 9.26 VCAM1 LDLR
2 clathrin-coated pit GO:0005905 9.16 LDLR HSPD1
3 early endosome GO:0005769 9.13 VCAM1 LDLR HSPD1
4 cell surface GO:0009986 8.92 VCAM1 LDLR HSPD1 APOH

Biological processes related to Autoimmune Atherosclerosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of inflammatory response GO:0050729 9.26 LDLR HSPD1
2 response to unfolded protein GO:0006986 9.16 HSPD1 HSPA14
3 T cell activation GO:0042110 8.96 HSPD1 FOXP3
4 protein refolding GO:0042026 8.62 HSPD1 HSPA14

Sources for Autoimmune Atherosclerosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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