AIS1
MCID: ATM052
MIFTS: 36

Autoimmune Disease 1 (AIS1)

Categories: Genetic diseases

Aliases & Classifications for Autoimmune Disease 1

MalaCards integrated aliases for Autoimmune Disease 1:

Name: Autoimmune Disease 1 57 72 29 6
Vitiligo-Associated Multiple Autoimmune Disease Susceptibility 2 57 72
Autoimmune Disease, Susceptibility to, 1 57 13
Autoimmune Diseases 44 70
Vamas2 57 72
Ais1 57 72
Vitiligo-Associated Multiple Autoimmune Disease Susceptibility 2; Vamas2 57
Autoimmune Disease Susceptibility Locus, Chromosome 1p-Related 57
Autoimmune Disease Susceptibility Locus Chromosome 1p-Related 72
Vitiligo-Associated Multiple Autoimmune Disease Type 2 72
Autoimmune Disease, Susceptibility to, Type 1 39
Autoimmune Disease Susceptibility 1 72

Characteristics:

OMIM®:

57 (Updated 05-Apr-2021)
Inheritance:
autosomal dominant

Miscellaneous:
early age at onset (13 years)


HPO:

31
autoimmune disease 1:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

OMIM® 57 607836
MeSH 44 D001327
MedGen 41 C1842979
SNOMED-CT via HPO 68 21983002 263681008 56727007
UMLS 70 C0004364

Summaries for Autoimmune Disease 1

UniProtKB/Swiss-Prot : 72 Autoimmune disease 1: An autoimmune disorder characterized by the association of vitiligo with autoimmune thyroiditis (Hashimoto thyroiditis).

MalaCards based summary : Autoimmune Disease 1, also known as vitiligo-associated multiple autoimmune disease susceptibility 2, is related to vitiligo-associated multiple autoimmune disease susceptibility 1 and autoimmune disease of the nervous system. An important gene associated with Autoimmune Disease 1 is FOXD3 (Forkhead Box D3). The drugs Sofosbuvir and Ledipasvir have been mentioned in the context of this disorder. Affiliated tissues include thyroid, bone marrow and bone, and related phenotypes are hashimoto thyroiditis and vitiligo

More information from OMIM: 607836

Related Diseases for Autoimmune Disease 1

Diseases related to Autoimmune Disease 1 via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 980, show less)
# Related Disease Score Top Affiliating Genes
1 vitiligo-associated multiple autoimmune disease susceptibility 1 11.3
2 autoimmune disease of the nervous system 11.2
3 pemphigus 11.1
4 celiac disease 1 11.1
5 graves' disease 11.1
6 interstitial lung disease 11.1
7 dermatomyositis 11.1
8 sjogren syndrome 11.1
9 premature menopause 11.1
10 polymyositis 11.0
11 stiff-person syndrome 11.0
12 mixed connective tissue disease 11.0
13 neuromyelitis optica 11.0
14 autoimmune disease, multisystem, infantile-onset, 1 10.9
15 cutaneous lupus erythematosus 10.9
16 adult-onset still's disease 10.9
17 scleroderma, familial progressive 10.9
18 heart block, congenital 10.9
19 autoimmune encephalitis 10.9
20 optic neuritis 10.9
21 immunoglobulin a deficiency 1 10.9
22 pemphigus foliaceus 10.9
23 lambert-eaton myasthenic syndrome 10.9
24 hypoparathyroidism 10.9
25 eosinophilic fasciitis 10.9
26 autoimmune polyendocrine syndrome, type i, with or without reversible metaphyseal dysplasia 10.9
27 membranoproliferative glomerulonephritis 10.9
28 neuromuscular disease 10.9
29 c1q deficiency 10.9
30 capillary leak syndrome 10.9
31 immune system disease 10.9
32 distal renal tubular acidosis 10.9
33 alopecia areata 1 10.8
34 bronchiectasis with or without elevated sweat chloride 1 10.8
35 complement component 2 deficiency 10.8
36 spondyloenchondrodysplasia with immune dysregulation 10.8
37 lipodystrophy, partial, acquired 10.8
38 bronchiectasis with or without elevated sweat chloride 2 10.8
39 bronchiectasis with or without elevated sweat chloride 3 10.8
40 complement component 3 deficiency, autosomal recessive 10.8
41 facial dysmorphism, immunodeficiency, livedo, and short stature 10.8
42 melioidosis 10.8
43 yao syndrome 10.8
44 selective igm deficiency disease 10.8
45 immunoglobulin beta deficiency 10.8
46 scleroperikeratitis 10.8
47 brawny scleritis 10.8
48 sclerosing keratitis 10.8
49 spinal cord disease 10.8
50 complement component 3 deficiency 10.8
51 subcorneal pustular dermatosis 10.8
52 erythromelalgia 10.8
53 acquired angioedema 10.8
54 autoimmune polyglandular syndrome type 3 10.8
55 autoimmune retinopathy 10.8
56 collagenous gastritis 10.8
57 ichthyosis, acquired 10.8
58 idiopathic hypertrophic pachymeningitis 10.8
59 localized lipodystrophy 10.8
60 vasculitis 10.8
61 myasthenia gravis 10.8
62 type 1 diabetes mellitus 10.8
63 connective tissue disease 10.7
64 inflammatory bowel disease 10.7
65 systemic scleroderma 10.7
66 antiphospholipid syndrome 10.7
67 allergic encephalomyelitis 10.7
68 hypothyroidism 10.7
69 primary biliary cholangitis 10.7
70 inflammatory spondylopathy 10.6
71 spondylitis 10.6
72 spondyloarthropathy 1 10.6
73 purpura 10.6
74 rheumatoid arthritis 10.6
75 uveitis 10.6
76 juvenile rheumatoid arthritis 10.6
77 crohn's disease 10.6
78 autoimmune hepatitis 10.6
79 thyroid gland disease 10.5
80 psoriatic arthritis 10.5
81 hemolytic anemia 10.5
82 sarcoidosis 1 10.5
83 multiple sclerosis 10.5
84 ulcerative colitis 10.5
85 myositis 10.5
86 glomerulonephritis 10.5
87 psoriasis 10.5
88 systemic autoimmune disease 10.5
89 guillain-barre syndrome 10.5
90 pustulosis of palm and sole 10.5
91 anemia, autoimmune hemolytic 10.5
92 alopecia 10.5
93 pernicious anemia 10.5
94 cholangitis 10.5
95 graft-versus-host disease 10.4
96 pemphigoid 10.4
97 gastritis 10.4
98 skin disease 10.4
99 alopecia areata 10.4
100 granulomatosis with polyangiitis 10.4
101 pemphigus vulgaris, familial 10.4
102 myopathy 10.4
103 hyperthyroidism 10.4
104 dermatitis, atopic 10.4
105 arthritis 10.4
106 polyarteritis nodosa 10.4
107 cytokine deficiency 10.4
108 sclerosing cholangitis 10.4
109 thrombocytopenia 10.4
110 vascular disease 10.4
111 temporal arteritis 10.4
112 thrombocytopenic purpura, autoimmune 10.4
113 cryoglobulinemia 10.4
114 anca-associated vasculitis 10.4
115 cholangitis, primary sclerosing 10.4
116 lymphoma 10.4
117 lung disease 10.4
118 liver cirrhosis 10.3
119 diabetes mellitus 10.3
120 bullous pemphigoid 10.3
121 aplastic anemia 10.3
122 pulmonary fibrosis and/or bone marrow failure, telomere-related, 2 10.3
123 bacterial infectious disease 10.3
124 collagen disease 10.3
125 urticaria 10.3
126 thrombocytopenia due to platelet alloimmunization 10.3
127 neuritis 10.3
128 myocarditis 10.3
129 atherosclerosis susceptibility 10.3
130 lymphoma, hodgkin, classic 10.3
131 covid-19 10.3
132 allergic disease 10.3
133 severe acute respiratory syndrome 10.3
134 b-cell lymphoma 10.3
135 raynaud phenomenon 10.3
136 immune deficiency disease 10.3
137 rheumatic fever-related antigen 10.3
138 thymoma, familial 10.3
139 kawasaki disease 10.3
140 crohn's colitis 10.3
141 rheumatic fever 10.3
142 thymoma 10.3
143 microscopic polyangiitis 10.3
144 autoimmune gastritis 10.3
145 neutropenia 10.3
146 polyendocrinopathy 10.3
147 polyneuropathy 10.2
148 relapsing-remitting multiple sclerosis 10.2
149 churg-strauss syndrome 10.2
150 severe combined immunodeficiency 10.2
151 fibromyalgia 10.2
152 lymphoma, non-hodgkin, familial 10.2
153 autoimmune uveitis 10.2
154 rickets 10.2
155 gout 10.2
156 demyelinating disease 10.2
157 pulmonary fibrosis 10.2
158 undifferentiated connective tissue disease 10.2
159 dermatitis herpetiformis, familial 10.2
160 hepatitis c virus 10.2
161 immunoglobulin alpha deficiency 10.2
162 leukemia 10.2
163 dermatitis 10.2
164 dermatitis herpetiformis 10.2
165 encephalitis 10.2
166 hypoadrenocorticism, familial 10.2
167 proteinuria, chronic benign 10.2
168 autoimmune pancreatitis 10.2
169 disease by infectious agent 10.2
170 exanthem 10.2
171 childhood type dermatomyositis 10.2
172 candidiasis 10.2
173 relapsing polychondritis 10.2
174 lymphopenia 10.2
175 localized scleroderma 10.2
176 leukemia, chronic lymphocytic 10.2
177 osteoporosis 10.2
178 schizophrenia 10.2
179 thrombophilia due to thrombin defect 10.2
180 graves disease 1 10.2
181 deficiency anemia 10.2
182 lymphoproliferative syndrome 10.2
183 common variable immunodeficiency 10.2
184 enthesopathy 10.2
185 pneumonia 10.2
186 herpes zoster 10.2
187 atrophic gastritis 10.2
188 lichen planus 10.2
189 autism 10.1
190 proteasome-associated autoinflammatory syndrome 1 10.1
191 immunodysregulation, polyendocrinopathy, and enteropathy, x-linked 10.1
192 mycobacterium tuberculosis 1 10.1
193 bone mineral density quantitative trait locus 8 10.1
194 bone mineral density quantitative trait locus 15 10.1
195 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.1
196 autism spectrum disorder 10.1
197 chronic urticaria 10.1
198 sialadenitis 10.1
199 pneumocystosis 10.1
200 arthropathy 10.1
201 rhinitis 10.1
202 chronic inflammatory demyelinating polyradiculoneuropathy 10.1
203 eye disease 10.1
204 iridocyclitis 10.1
205 allergic angiitis 10.1
206 homologous wasting disease 10.1
207 discoid lupus erythematosus 10.1
208 behcet syndrome 10.1
209 cryoglobulinemia, familial mixed 10.1
210 takayasu arteritis 10.1
211 goodpasture syndrome 10.1
212 helicobacter pylori infection 10.1
213 autoimmune lymphoproliferative syndrome 10.1
214 diffuse large b-cell lymphoma 10.1
215 colitis 10.1
216 igg4-related disease 10.1
217 thrombotic thrombocytopenic purpura 10.1
218 respiratory failure 10.1
219 goiter 10.1
220 dilated cardiomyopathy 10.1
221 hepatitis 10.1
222 demyelinating polyneuropathy 10.1
223 chronic graft versus host disease 10.1
224 amyotrophic lateral sclerosis 1 10.1
225 lymphoma, mucosa-associated lymphoid type 10.1
226 pulmonary hypertension, primary, 1 10.1
227 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.1
228 myeloma, multiple 10.1
229 asthma 10.1
230 allergic rhinitis 10.1
231 myelodysplastic syndrome 10.1
232 membranous nephropathy 10.1
233 hyperprolactinemia 10.1
234 pulmonary hypertension 10.1
235 crest syndrome 10.1
236 glucocorticoid-induced osteoporosis 10.1
237 thrombosis 10.1
238 combined immunodeficiency 10.1
239 pre-eclampsia 10.1
240 henoch-schoenlein purpura 10.1
241 nephrotic syndrome 10.1
242 pancytopenia 10.1
243 hepatitis c 10.1
244 lateral sclerosis 10.1
245 epidermolysis bullosa 10.1
246 endometriosis 10.1
247 lipid metabolism disorder 10.1
248 myelitis 10.1
249 infertility 10.1
250 gastrointestinal system disease 10.1
251 measles 10.1
252 neuropathy 10.1
253 pulmonary embolism 10.1
254 acute graft versus host disease 10.1
255 multifocal motor neuropathy 10.1
256 vitiligo-associated multiple autoimmune disease susceptibility 6 10.1
257 breast cancer 10.0
258 type 2 diabetes mellitus 10.0
259 attention deficit-hyperactivity disorder 10.0
260 chorea, childhood-onset, with psychomotor retardation 10.0
261 atrioventricular block 10.0
262 erythema nodosum 10.0
263 urinary tract infection 10.0
264 sensorineural hearing loss 10.0
265 silicosis 10.0
266 choreatic disease 10.0
267 keratoconjunctivitis sicca 10.0
268 eclampsia 10.0
269 autoimmune polyendocrine syndrome 10.0
270 cystitis 10.0
271 acute kidney failure 10.0
272 food allergy 10.0
273 epidermolysis bullosa acquisita 10.0
274 sleep disorder 10.0
275 peripheral nervous system disease 10.0
276 chickenpox 10.0
277 myeloid leukemia 10.0
278 evans' syndrome 10.0
279 acquired hemophilia 10.0
280 lymphomatous thyroiditis 10.0
281 macrophage activation syndrome 10.0
282 oral lichen planus 10.0
283 thyroid carcinoma 10.0
284 pfeiffer syndrome 10.0
285 ige responsiveness, atopic 10.0
286 raynaud disease 10.0
287 ataxia and polyneuropathy, adult-onset 10.0
288 aging 10.0
289 leukemia, acute myeloid 10.0
290 systemic lupus erythematosus 1 10.0
291 systemic lupus erythematosus 3 10.0
292 juvenile arthritis 10.0
293 limbic encephalitis 10.0
294 transverse myelitis 10.0
295 parkinsonism 10.0
296 pleurisy 10.0
297 chlamydia 10.0
298 cicatricial pemphigoid 10.0
299 telangiectasis 10.0
300 pure red-cell aplasia 10.0
301 pericarditis 10.0
302 viral hepatitis 10.0
303 hepatitis b 10.0
304 turner syndrome 10.0
305 polyradiculoneuropathy 10.0
306 proliferative glomerulonephritis 10.0
307 acne 10.0
308 adenoma 10.0
309 peptic ulcer disease 10.0
310 end stage renal disease 10.0
311 periodontitis 10.0
312 narcolepsy 10.0
313 amyloidosis 10.0
314 keratoconjunctivitis 10.0
315 hypersensitivity vasculitis 10.0
316 hypereosinophilic syndrome 10.0
317 hypoglycemia 10.0
318 hemophilia 10.0
319 cold agglutinin disease 10.0
320 depression 10.0
321 autonomic dysfunction 10.0
322 encephalopathy 10.0
323 subacute cutaneous lupus erythematosus 10.0
324 toxic oil syndrome 10.0
325 pik3ca-related overgrowth syndrome 10.0
326 hypercholesterolemia, familial, 1 9.9
327 keratitis, hereditary 9.9
328 migraine with or without aura 1 9.9
329 obsessive-compulsive disorder 9.9
330 psoriasis 1 9.9
331 pulmonary fibrosis, idiopathic 9.9
332 triiodothyronine receptor auxiliary protein 9.9
333 lung cancer 9.9
334 leprosy 3 9.9
335 myxedema 9.9
336 yemenite deaf-blind hypopigmentation syndrome 9.9
337 branchiootic syndrome 1 9.9
338 anorexia nervosa 9.9
339 bulimia nervosa 9.9
340 kala-azar 1 9.9
341 major affective disorder 8 9.9
342 major affective disorder 9 9.9
343 multiple sclerosis 2 9.9
344 helix syndrome 9.9
345 gastrointestinal ulceration, recurrent, with dysfunctional platelets 9.9
346 vitamin b12 deficiency 9.9
347 marginal zone b-cell lymphoma 9.9
348 rheumatic heart disease 9.9
349 follicular lymphoma 9.9
350 cutaneous t cell lymphoma 9.9
351 collagenous colitis 9.9
352 bone resorption disease 9.9
353 chronic spontaneous urticaria 9.9
354 autoimmune myocarditis 9.9
355 human cytomegalovirus infection 9.9
356 paraneoplastic pemphigus 9.9
357 rapidly involuting congenital hemangioma 9.9
358 hypogonadotropic hypogonadism 9.9
359 parotitis 9.9
360 spondyloarthropathy 9.9
361 adult respiratory distress syndrome 9.9
362 chagas disease 9.9
363 crescentic glomerulonephritis 9.9
364 scleritis 9.9
365 squamous cell papilloma 9.9
366 amenorrhea 9.9
367 interstitial cystitis 9.9
368 toxic shock syndrome 9.9
369 gonadal dysgenesis 9.9
370 cholera 9.9
371 angioedema 9.9
372 melanoma 9.9
373 constipation 9.9
374 thrombophilia 9.9
375 psychotic disorder 9.9
376 orchitis 9.9
377 agammaglobulinemia 9.9
378 papilloma 9.9
379 iga glomerulonephritis 9.9
380 bipolar disorder 9.9
381 mood disorder 9.9
382 skin carcinoma 9.9
383 hyperglycemia 9.9
384 acquired immunodeficiency syndrome 9.9
385 acute disseminated encephalomyelitis 9.9
386 cerebrovascular disease 9.9
387 t-cell lymphoblastic leukemia/lymphoma 9.9
388 chronic kidney disease 9.9
389 eating disorder 9.9
390 leishmaniasis 9.9
391 allergic asthma 9.9
392 irritable bowel syndrome 9.9
393 autoimmune atrophic gastritis 9.9
394 glioma 9.9
395 hansen's disease 9.9
396 leukemia, t-cell, chronic 9.9
397 splenomegaly 9.9
398 stevens-johnson syndrome/toxic epidermal necrolysis 9.9
399 systemic onset juvenile idiopathic arthritis 9.9
400 dysphagia 9.9
401 headache 9.9
402 myoclonus 9.9
403 secondary vasculitis 9.9
404 autoimmune hepatitis type 1 9.9
405 diffuse alveolar hemorrhage 9.9
406 autoinflammatory syndrome 9.9
407 hashimoto thyroiditis 9.9
408 autoimmune disease 2 9.9
409 autoimmune disease 3 9.9
410 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 9.9
411 thyroiditis 9.9
412 alzheimer disease 9.8
413 atrial standstill 1 9.8
414 gastroesophageal reflux 9.8
415 factor viii deficiency 9.8
416 fibrosis of extraocular muscles, congenital, 1 9.8
417 hand skill, relative 9.8
418 periodic fever, familial, autosomal dominant 9.8
419 hypertension, essential 9.8
420 hypertriglyceridemia, familial 9.8
421 inclusion body myositis 9.8
422 dowling-degos disease 1 9.8
423 down syndrome 9.8
424 suppressor of tumorigenicity 3 9.8
425 chondrodysplasia punctata syndrome 9.8
426 hemolytic uremic syndrome, atypical 1 9.8
427 periodontitis, chronic 9.8
428 asplenia, isolated congenital 9.8
429 thrombocytopenia 3 9.8
430 wiskott-aldrich syndrome 9.8
431 hemophilia a 9.8
432 macular degeneration, age-related, 1 9.8
433 homocysteinemia 9.8
434 cervical cancer 9.8
435 cataract 26, multiple types 9.8
436 leukemia, chronic myeloid 9.8
437 systemic lupus erythematosus 4 9.8
438 severe cutaneous adverse reaction 9.8
439 human immunodeficiency virus type 1 9.8
440 systemic lupus erythematosus 5 9.8
441 malaria 9.8
442 celiac disease 6 9.8
443 acute promyelocytic leukemia 9.8
444 leukemia, acute lymphoblastic 9.8
445 reynolds syndrome 9.8
446 gastric cancer 9.8
447 agenesis of corpus callosum, cardiac, ocular, and genital syndrome 9.8
448 chlamydia pneumonia 9.8
449 bacterial sepsis 9.8
450 autoimmune vasculitis 9.8
451 pemphigus gestationis 9.8
452 autoimmune polyendocrine syndrome type 1 9.8
453 erythema multiforme 9.8
454 multinodular goiter 9.8
455 female breast cancer 9.8
456 autosomal recessive disease 9.8
457 secondary progressive multiple sclerosis 9.8
458 sleep apnea 9.8
459 hemorrhagic cystitis 9.8
460 cogan syndrome 9.8
461 bone disease 9.8
462 nodal marginal zone lymphoma 9.8
463 b-lymphoblastic leukemia/lymphoma 9.8
464 autoimmune cholangitis 9.8
465 familial cold autoinflammatory syndrome 9.8
466 interstitial nephritis 9.8
467 hydrocephalus 9.8
468 brucellosis 9.8
469 plummer's disease 9.8
470 tetanus 9.8
471 heart disease 9.8
472 diphtheria 9.8
473 esophagitis 9.8
474 aseptic meningitis 9.8
475 plica syndrome 9.8
476 vogt-koyanagi-harada disease 9.8
477 bell's palsy 9.8
478 hepatitis a 9.8
479 hemolytic-uremic syndrome 9.8
480 acute leukemia 9.8
481 acute cystitis 9.8
482 nodular goiter 9.8
483 cholestasis 9.8
484 pemphigoid gestationis 9.8
485 hypersensitivity reaction type iii disease 9.8
486 alcohol use disorder 9.8
487 pneumothorax 9.8
488 calcinosis 9.8
489 epilepsy 9.8
490 mononeuritis multiplex 9.8
491 hyperuricemia 9.8
492 hypogonadism 9.8
493 chronic mucocutaneous candidiasis 9.8
494 gastroenteritis 9.8
495 arteriosclerosis 9.8
496 iron metabolism disease 9.8
497 synovitis 9.8
498 bronchiolitis obliterans 9.8
499 euthyroid sick syndrome 9.8
500 bronchiolitis 9.8
501 inner ear disease 9.8
502 gingivitis 9.8
503 cellulitis 9.8
504 aortic aneurysm 9.8
505 liver disease 9.8
506 syphilis 9.8
507 hypertrichosis 9.8
508 pancreatitis 9.8
509 aortitis 9.8
510 dystonia 9.8
511 conjunctivitis 9.8
512 reactive arthritis 9.8
513 progressive multifocal leukoencephalopathy 9.8
514 cataract 9.8
515 influenza 9.8
516 herpes simplex 9.8
517 rubella 9.8
518 rosacea 9.8
519 macroglobulinemia 9.8
520 visceral leishmaniasis 9.8
521 achalasia 9.8
522 exophthalmos 9.8
523 bronchiectasis 9.8
524 fasciitis 9.8
525 stomatitis 9.8
526 aphthous stomatitis 9.8
527 yellow fever 9.8
528 muscular dystrophy 9.8
529 47,xyy 9.8
530 al amyloidosis 9.8
531 autoimmune enteropathy 9.8
532 catastrophic antiphospholipid syndrome 9.8
533 chromosomal triplication 9.8
534 hypomelanotic disorder 9.8
535 kikuchi disease 9.8
536 linear iga disease 9.8
537 pediatric ulcerative colitis 9.8
538 pleuroparenchymal fibroelastosis 9.8
539 wells syndrome 9.8
540 dysautonomia 9.8
541 hypoxia 9.8
542 tremor 9.8
543 glial tumor 9.8
544 acute transverse myelitis 9.8
545 idiopathic nephrotic syndrome 9.8
546 neonatal lupus erythematosus 9.8
547 erythema multiforme major 9.8
548 argyria 9.8
549 autoimmune hepatitis type 2 9.8
550 x-linked intellectual disability-macrocephaly-macroorchidism syndrome 9.8
551 severe immune-mediated enteropathy 9.8
552 autoimmune disease 9.8
553 systemic lupus erythematosus 9.8
554 lupus erythematosus 9.8
555 aortic aneurysm, familial abdominal, 1 9.7
556 bladder cancer 9.7
557 burkitt lymphoma 9.7
558 hepatocellular carcinoma 9.7
559 cardiac arrhythmia 9.7
560 cardiac conduction defect 9.7
561 seizures, benign familial neonatal, 1 9.7
562 creutzfeldt-jakob disease 9.7
563 cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 1 9.7
564 erythermalgia, primary 9.7
565 esophageal cancer 9.7
566 felty syndrome 9.7
567 glioma susceptibility 1 9.7
568 huntington disease 9.7
569 renal cell carcinoma, nonpapillary 9.7
570 kaposi sarcoma 9.7
571 lichen sclerosus et atrophicus 9.7
572 meniere disease 9.7
573 moebius syndrome 9.7
574 myelopathy, htlv-1-associated 9.7
575 noonan syndrome 1 9.7
576 parkinson disease, late-onset 9.7
577 piebald trait 9.7
578 prostate cancer 9.7
579 retinitis pigmentosa 10 9.7
580 schistosoma mansoni infection, susceptibility/ 9.7
581 blau syndrome 9.7
582 telangiectasia, hereditary benign 9.7
583 thrombocytopenia 2 9.7
584 muckle-wells syndrome 9.7
585 williams-beuren syndrome 9.7
586 zinc finger protein 1 9.7
587 lipoid congenital adrenal hyperplasia 9.7
588 alopecia universalis congenita 9.7
589 arterial calcification, generalized, of infancy, 1 9.7
590 ataxia-telangiectasia 9.7
591 chondrosarcoma 9.7
592 cryptorchidism, unilateral or bilateral 9.7
593 endocardial fibroelastosis 9.7
594 enterocolitis 9.7
595 factor v deficiency 9.7
596 hutterite cerebroosteonephrodysplasia syndrome 9.7
597 hydrops fetalis, nonimmune 9.7
598 hypogonadism, male 9.7
599 kuru 9.7
600 lambert syndrome 9.7
601 familial mediterranean fever 9.7
602 moyamoya disease 1 9.7
603 mycosis fungoides 9.7
604 myelofibrosis 9.7
605 3-methylglutaconic aciduria, type iii 9.7
606 pancreatic cancer 9.7
607 subacute sclerosing panencephalitis 9.7
608 hyper-igd syndrome 9.7
609 scott syndrome 9.7
610 polycythemia vera 9.7
611 insulin-like growth factor i 9.7
612 body mass index quantitative trait locus 11 9.7
613 hypomelanosis of ito 9.7
614 aland island eye disease 9.7
615 cyclic vomiting syndrome 9.7
616 retinitis pigmentosa 11 9.7
617 pituitary adenoma, prolactin-secreting 9.7
618 gallbladder disease 1 9.7
619 hyperferritinemia with or without cataract 9.7
620 cd4/cd8 t-cell ratio 9.7
621 body mass index quantitative trait locus 9 9.7
622 myotonic dystrophy 2 9.7
623 psoriasis 2 9.7
624 body mass index quantitative trait locus 8 9.7
625 brittle bone disorder 9.7
626 rheumatoid arthritis, systemic juvenile 9.7
627 inflammatory bowel disease 3 9.7
628 orthostatic intolerance 9.7
629 systemic lupus erythematosus 2 9.7
630 dianzani autoimmune lymphoproliferative disease 9.7
631 psoriasis 6 9.7
632 neurodegeneration with brain iron accumulation 3 9.7
633 body mass index quantitative trait locus 1 9.7
634 pulmonary disease, chronic obstructive 9.7
635 aortic aneurysm, familial thoracic 1 9.7
636 nasopharyngeal carcinoma 9.7
637 meningioma, familial 9.7
638 coronary heart disease 1 9.7
639 body mass index quantitative trait locus 4 9.7
640 body mass index quantitative trait locus 10 9.7
641 systemic lupus erythematosus with nephritis 3 9.7
642 endometrial cancer 9.7
643 body mass index quantitative trait locus 7 9.7
644 lung cancer susceptibility 1 9.7
645 celiac disease 3 9.7
646 systemic lupus erythematosus 7 9.7
647 systemic lupus erythematosus 8 9.7
648 esophagitis, eosinophilic, 1 9.7
649 systemic lupus erythematosus 9 9.7
650 ewing sarcoma 9.7
651 systemic lupus erythematosus 10 9.7
652 systemic lupus erythematosus 12 9.7
653 inflammatory bowel disease 16 9.7
654 body mass index quantitative trait locus 12 9.7
655 systemic lupus erythematosus 13 9.7
656 psoriasis 10 9.7
657 body mass index quantitative trait locus 14 9.7
658 microvascular complications of diabetes 3 9.7
659 microvascular complications of diabetes 4 9.7
660 microvascular complications of diabetes 6 9.7
661 microvascular complications of diabetes 7 9.7
662 premature ovarian failure 7 9.7
663 complement component c1s deficiency 9.7
664 candidiasis, familial, 6 9.7
665 aspergillosis 9.7
666 immunodeficiency 31c 9.7
667 systemic lupus erythematosus 16 9.7
668 multiple sclerosis 5 9.7
669 human herpesvirus 8 9.7
670 mandibular hypoplasia, deafness, progeroid features, and lipodystrophy syndrome 9.7
671 body mass index quantitative trait locus 18 9.7
672 alacrima, achalasia, and mental retardation syndrome 9.7
673 glucocorticoid resistance, generalized 9.7
674 metabolic crises, recurrent, with rhabdomyolysis, cardiac arrhythmias, and neurodegeneration 9.7
675 lymphatic malformation 7 9.7
676 body mass index quantitative trait locus 19 9.7
677 encephalopathy, progressive, early-onset, with episodic rhabdomyolysis 9.7
678 neurodevelopmental, jaw, eye, and digital syndrome 9.7
679 angina pectoris 9.7
680 drug-induced lupus erythematosus 9.7
681 autoimmune glomerulonephritis 9.7
682 hirata disease 9.7
683 hemophagocytic lymphohistiocytosis 9.7
684 aspiration pneumonia 9.7
685 cryptogenic organizing pneumonia 9.7
686 tick-borne encephalitis 9.7
687 epidemic typhus 9.7
688 adult t-cell leukemia 9.7
689 brachydactyly 9.7
690 aicardi-goutieres syndrome 9.7
691 small cell carcinoma 9.7
692 chorioamnionitis 9.7
693 lymphoplasmacytic lymphoma 9.7
694 peripheral t-cell lymphoma 9.7
695 metabolic acidosis 9.7
696 primary progressive multiple sclerosis 9.7
697 first-degree atrioventricular block 9.7
698 infective endocarditis 9.7
699 interleukin-7 receptor alpha deficiency 9.7
700 pervasive developmental disorder 9.7
701 alexithymia 9.7
702 stuttering 9.7
703 ptosis 9.7
704 x-linked chondrodysplasia punctata 1 9.7
705 inguinal hernia 9.7
706 drug allergy 9.7
707 griscelli syndrome 9.7
708 chronic myelomonocytic leukemia 9.7
709 polycystic kidney disease 9.7
710 hyper ige syndrome 9.7
711 non-alcoholic steatohepatitis 9.7
712 multisystem inflammatory syndrome in children 9.7
713 intracranial meningioma 9.7
714 latent autoimmune diabetes in adults 9.7
715 castleman disease 9.7
716 migraine with aura 9.7
717 venous insufficiency 9.7
718 xerophthalmia 9.7
719 osteonecrosis 9.7
720 neuroretinitis 9.7
721 osteomyelitis 9.7
722 mumps 9.7
723 endocarditis 9.7
724 pneumoconiosis 9.7
725 anthracosis 9.7
726 mooren's ulcer 9.7
727 nasopharyngitis 9.7
728 esophageal atresia 9.7
729 osteomalacia 9.7
730 mastitis 9.7
731 portal hypertension 9.7
732 lepromatous leprosy 9.7
733 gastrojejunal ulcer 9.7
734 hemiplegia 9.7
735 discitis 9.7
736 anhidrosis 9.7
737 t cell deficiency 9.7
738 primary hyperparathyroidism 9.7
739 disseminated intravascular coagulation 9.7
740 microcytic anemia 9.7
741 rabies 9.7
742 erysipelas 9.7
743 pulmonary edema 9.7
744 hemopericardium 9.7
745 autonomic neuropathy 9.7
746 retinal vasculitis 9.7
747 listeria meningitis 9.7
748 cauda equina syndrome 9.7
749 polycystic ovary syndrome 9.7
750 hyperandrogenism 9.7
751 dysgammaglobulinemia 9.7
752 gestational diabetes 9.7
753 pericardial effusion 9.7
754 coronary thrombosis 9.7
755 mononeuropathy 9.7
756 hypertrophic cardiomyopathy 9.7
757 panuveitis 9.7
758 hemosiderosis 9.7
759 lymphocytic choriomeningitis 9.7
760 tinea corporis 9.7
761 shigellosis 9.7
762 tinea pedis 9.7
763 von willebrand's disease 9.7
764 hepatic coma 9.7
765 acoustic neuroma 9.7
766 intermediate uveitis 9.7
767 thyroid crisis 9.7
768 cardiovascular system disease 9.7
769 shipyard eye 9.7
770 dementia 9.7
771 hellp syndrome 9.7
772 megaesophagus 9.7
773 nontoxic goiter 9.7
774 diarrhea 9.7
775 mycoplasma pneumoniae pneumonia 9.7
776 scrub typhus 9.7
777 cardiac sarcoidosis 9.7
778 hepatic encephalopathy 9.7
779 tuberous sclerosis 9.7
780 hyperparathyroidism 9.7
781 sapho syndrome 9.7
782 schistosomiasis 9.7
783 iritis 9.7
784 adult dermatomyositis 9.7
785 renal tubular acidosis 9.7
786 oral candidiasis 9.7
787 acute cholangitis 9.7
788 prostatitis 9.7
789 hereditary angioedema 9.7
790 disease of mental health 9.7
791 panniculitis 9.7
792 pleural disease 9.7
793 arthus reaction 9.7
794 fungal infectious disease 9.7
795 limited scleroderma 9.7
796 lymphadenitis 9.7
797 neuroendocrine tumor 9.7
798 optic nerve disease 9.7
799 cerebral palsy 9.7
800 neuroma 9.7
801 post-traumatic stress disorder 9.7
802 intestinal perforation 9.7
803 ectodermal dysplasia 9.7
804 dental caries 9.7
805 thrombocytosis 9.7
806 prothrombin deficiency 9.7
807 spondylosis 9.7
808 hidradenitis suppurativa 9.7
809 hidradenitis 9.7
810 keratopathy 9.7
811 motor neuron disease 9.7
812 sensory peripheral neuropathy 9.7
813 testicular disease 9.7
814 larynx cancer 9.7
815 kidney cancer 9.7
816 contact dermatitis 9.7
817 pulmonary tuberculosis 9.7
818 testicular cancer 9.7
819 substance abuse 9.7
820 malignant astrocytoma 9.7
821 tropical spastic paraparesis 9.7
822 central nervous system lymphoma 9.7
823 rhabdomyosarcoma 9.7
824 thymic carcinoma 9.7
825 plague 9.7
826 necrobiosis lipoidica 9.7
827 chronic wasting disease 9.7
828 retinitis 9.7
829 gastric adenocarcinoma 9.7
830 plasmacytoma 9.7
831 granuloma annulare 9.7
832 anovulation 9.7
833 pleural empyema 9.7
834 porokeratosis 9.7
835 thrombophlebitis 9.7
836 insulinoma 9.7
837 acute myocarditis 9.7
838 eosinophilic gastroenteritis 9.7
839 heart valve disease 9.7
840 pyoderma 9.7
841 coronary restenosis 9.7
842 coronary stenosis 9.7
843 conjunctivochalasis 9.7
844 polyradiculopathy 9.7
845 peanut allergy 9.7
846 granulomatous dermatitis 9.7
847 hypokalemia 9.7
848 pleomorphic adenoma 9.7
849 secretory meningioma 9.7
850 lymphoplasmacyte-rich meningioma 9.7
851 gastric neuroendocrine neoplasm 9.7
852 calciphylaxis 9.7
853 immune-complex glomerulonephritis 9.7
854 movement disease 9.7
855 poliomyelitis 9.7
856 epidermolysis bullosa dystrophica 9.7
857 borna disease 9.7
858 arteriosclerosis obliterans 9.7
859 von economo's disease 9.7
860 human immunodeficiency virus infectious disease 9.7
861 blepharospasm 9.7
862 intestinal disease 9.7
863 pituitary gland disease 9.7
864 gingival hypertrophy 9.7
865 colonic disease 9.7
866 scrapie 9.7
867 mediastinal cancer 9.7
868 kidney disease 9.7
869 t-cell acute lymphoblastic leukemia 9.7
870 lymphoepithelioma-like carcinoma 9.7
871 adenosine deaminase deficiency 9.7
872 pediatric lymphoma 9.7
873 eosinophilic pneumonia 9.7
874 congestive heart failure 9.7
875 paraplegia 9.7
876 plasma cell neoplasm 9.7
877 subacute thyroiditis 9.7
878 monoclonal gammopathy of uncertain significance 9.7
879 scabies 9.7
880 appendicitis 9.7
881 extrinsic allergic alveolitis 9.7
882 polycythemia 9.7
883 mucormycosis 9.7
884 rheumatoid arthritis interstitial lung disease 9.7
885 chronic fatigue syndrome 9.7
886 pyoderma gangrenosum 9.7
887 nervous system disease 9.7
888 neurofibromatosis 9.7
889 vascular dementia 9.7
890 bacterial pneumonia 9.7
891 erythema infectiosum 9.7
892 intermediate coronary syndrome 9.7
893 parasitic helminthiasis infectious disease 9.7
894 dermatophytosis 9.7
895 autosomal dominant polycystic kidney disease 9.7
896 peroxisomal disease 9.7
897 rem sleep behavior disorder 9.7
898 cutaneous leishmaniasis 9.7
899 dyskinesia of esophagus 9.7
900 hypopituitarism 9.7
901 chronic cholangitis 9.7
902 fatty liver disease 9.7
903 postpartum depression 9.7
904 dacryoadenitis 9.7
905 non-secretory myeloma 9.7
906 toxoplasmosis 9.7
907 eosinophilia-myalgia syndrome 9.7
908 albinism 9.7
909 keloid disorder 9.7
910 myotonic dystrophy 9.7
911 ankrd26-related thrombocytopenia 9.7
912 48,xyyy 9.7
913 acquired hemophilia a 9.7
914 acute zonal occult outer retinopathy 9.7
915 autoimmune inner ear disease 9.7
916 autoimmune oophoritis 9.7
917 banti's syndrome 9.7
918 central serous chorioretinopathy 9.7
919 cold urticaria 9.7
920 complement component deficiency 9.7
921 dense deposit disease 9.7
922 erosive pustular dermatosis of the scalp 9.7
923 giant cell myocarditis 9.7
924 gigantomastia 9.7
925 halo nevus 9.7
926 heparin-induced thrombocytopenia 9.7
927 htlv-1 associated myelopathy/tropical spastic paraparesis 9.7
928 lichen planus pemphigoides 9.7
929 linear scleroderma 9.7
930 macrophagic myofasciitis 9.7
931 myelodysplastic syndrome with excess blasts 9.7
932 opsoclonus-myoclonus syndrome 9.7
933 parainfluenza virus type 3 9.7
934 pediatric multiple sclerosis 9.7
935 persistent genital arousal disorder 9.7
936 post-transplant lymphoproliferative disease 9.7
937 primary agammaglobulinemia 9.7
938 primary angiitis of the central nervous system 9.7
939 primary central nervous system lymphoma 9.7
940 pseudo-turner syndrome 9.7
941 pustulosis palmaris et plantaris 9.7
942 rheumatoid vasculitis 9.7
943 rosai-dorfman disease 9.7
944 scleromyxedema 9.7
945 spastic paraparesis 9.7
946 spondylarthropathy 9.7
947 sudden sensorineural hearing loss 9.7
948 sutton disease 2 9.7
949 thalassemia 9.7
950 thrombotic thrombocytopenic purpura, acquired 9.7
951 warm antibody hemolytic anemia 9.7
952 aneurysm 9.7
953 cerebral aneurysms 9.7
954 myotonia 9.7
955 paraneoplastic syndromes 9.7
956 spasticity 9.7
957 syncope 9.7
958 chronic cutaneous lupus erythematosus 9.7
959 differentiated thyroid carcinoma 9.7
960 secondary hemophagocytic lymphohistiocytosis 9.7
961 autoimmune pancreatitis type 1 9.7
962 progressive muscular dystrophy 9.7
963 rare hereditary hemochromatosis 9.7
964 chronic enteropathy associated with slco2a1 gene 9.7
965 neonatal scleroderma 9.7
966 autoimmune encephalopathy with parasomnia and obstructive sleep apnea 9.7
967 granulomatous mastitis 9.7
968 acute liver failure 9.7
969 complications after hematopoietic stem cell transplantation 9.7
970 hyperpigmentation of the skin 9.7
971 large granular lymphocyte leukemia 9.7
972 refractory cytopenia with multilineage dysplasia 9.7
973 pediatric systemic lupus erythematosus 9.7
974 overgrowth syndrome 9.7
975 immune-mediated thrombotic thrombocytopenic purpura 9.7
976 adult-onset steinert myotonic dystrophy 9.7
977 refractory anemia 9.7
978 rare coagulation disorder 9.7
979 thyroid tumor 9.7
980 precursor t-cell acute lymphoblastic leukemia 9.7

Graphical network of the top 20 diseases related to Autoimmune Disease 1:



Diseases related to Autoimmune Disease 1

Symptoms & Phenotypes for Autoimmune Disease 1

Human phenotypes related to Autoimmune Disease 1:

31 (showing 2, show less)
# Description HPO Frequency HPO Source Accession
1 hashimoto thyroiditis 31 HP:0000872
2 vitiligo 31 HP:0001045

Symptoms via clinical synopsis from OMIM®:

57 (Updated 05-Apr-2021)
Skin Nails Hair Skin:
vitiligo, generalized
depigmentation, slowly progressive and diffuse

Endocrine Features:
hashimoto thyroiditis (some patients)

Clinical features from OMIM®:

607836 (Updated 05-Apr-2021)

Drugs & Therapeutics for Autoimmune Disease 1

Drugs for Autoimmune Disease 1 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 294, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Sofosbuvir Approved Phase 4 1190307-88-0 45375808
2
Ledipasvir Approved Phase 4 1256388-51-8 67505836
3
Mitoxantrone Approved, Investigational Phase 4 65271-80-9 4212
4
Prednisolone acetate Approved, Vet_approved Phase 4 52-21-1
5
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
6
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
7
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
8
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
9
rituximab Approved Phase 4 174722-31-7 10201696
10
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
11
Everolimus Approved Phase 4 159351-69-6 6442177 70789204
12
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
13
Thalidomide Approved, Investigational, Withdrawn Phase 4 50-35-1 5426
14
Naproxen Approved, Vet_approved Phase 4 22204-53-1 1302 156391
15
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
16
Cephalexin Approved, Investigational, Vet_approved Phase 4 15686-71-2 27447
17
Calcitriol Approved, Nutraceutical Phase 4 32222-06-3 5280453 134070
18
Prednisolone hemisuccinate Experimental Phase 4 2920-86-7
19 Immunoglobulins, Intravenous Phase 4
20 Antibodies Phase 4
21 Immunoglobulins Phase 4
22 Hormones Phase 4
23 Immunoglobulin A Phase 4
24 Calcium, Dietary Phase 4
25 Nutrients Phase 4
26 Trace Elements Phase 4
27 Vitamins Phase 4
28 Micronutrients Phase 4
29 Vasoconstrictor Agents Phase 4
30 Neuroprotective Agents Phase 4
31 Protective Agents Phase 4
32 Antineoplastic Agents, Immunological Phase 4
33 Methylprednisolone Acetate Phase 4
34 Antineoplastic Agents, Hormonal Phase 4
35 Antiemetics Phase 4
36 Antitubercular Agents Phase 4
37 Analgesics Phase 4
38 Analgesics, Non-Narcotic Phase 4
39 Anti-Inflammatory Agents, Non-Steroidal Phase 4
40 Angiogenesis Inhibitors Phase 4
41 Complement System Proteins Phase 4
42 Complement C3 Phase 4
43 Cyclooxygenase Inhibitors Phase 4
44 Cephalosporins Phase 4
45 methicillin Phase 4
46
Calcium Nutraceutical Phase 4 7440-70-2 271
47
Methotrexate Approved Phase 3 1959-05-2, 59-05-2 126941
48
Tofacitinib Approved, Investigational Phase 3 477600-75-2
49
Levoleucovorin Approved, Investigational Phase 3 68538-85-2 149436
50
Etanercept Approved, Investigational Phase 3 185243-69-0
51
Adalimumab Approved, Experimental Phase 3 331731-18-1 16219006
52
Infliximab Approved Phase 3 170277-31-3
53
Nitroglycerin Approved, Investigational Phase 3 55-63-0 4510
54
Sorafenib Approved, Investigational Phase 3 284461-73-0 216239 406563
55
Fludarabine Approved Phase 2, Phase 3 21679-14-1, 75607-67-9 30751
56
tannic acid Approved Phase 3 1401-55-4
57
Benzocaine Approved, Investigational Phase 3 1994-09-7, 94-09-7 2337
58
Folic acid Approved, Nutraceutical, Vet_approved Phase 3 59-30-3 6037
59
Abetimus Investigational Phase 3 167362-48-3
60
Molgramostim Investigational Phase 3 99283-10-0
61 Vitamin B9 Phase 3
62 Folic Acid Antagonists Phase 3
63 Vitamin B Complex Phase 3
64 Dermatologic Agents Phase 3
65 Antimetabolites Phase 3
66 Folate Phase 3
67 Vasodilator Agents Phase 3
68 Protein Kinase Inhibitors Phase 3
69 Liver Extracts Phase 3
70 Pharmaceutical Solutions Phase 3
71
Levamisole Approved, Investigational, Vet_approved, Withdrawn Phase 2 14769-73-4 26879
72
Methoxsalen Approved Phase 2 298-81-7 4114
73
Busulfan Approved, Investigational Phase 2 55-98-1 2478
74
Pancrelipase Approved, Investigational Phase 2 53608-75-6
75
Ranibizumab Approved Phase 2 347396-82-1 459903
76
Bevacizumab Approved, Investigational Phase 2 216974-75-3
77
Oxytetracycline Approved, Investigational, Vet_approved Phase 1, Phase 2 79-57-2 5280972 54715139
78
Abatacept Approved Phase 2 332348-12-6 10237
79
Cytarabine Approved, Investigational Phase 2 147-94-4 6253
80
Carmustine Approved, Investigational Phase 2 154-93-8 2578
81
Etoposide Approved Phase 2 33419-42-0 36462
82
Melphalan Approved Phase 2 148-82-3 4053 460612
83
Mechlorethamine Approved, Investigational Phase 2 51-75-2 4033
84
Miconazole Approved, Investigational, Vet_approved Phase 2 22916-47-8 4189