AIS3
MCID: ATM054
MIFTS: 18

Autoimmune Disease 3 (AIS3)

Aliases & Classifications for Autoimmune Disease 3

MalaCards integrated aliases for Autoimmune Disease 3:

Name: Autoimmune Disease 3 56
Autoimmune Disease, Susceptibility to, 3 56 13
Vitiligo-Associated Multiple Autoimmune Disease Susceptibility 4; Vamas4 56
Vitiligo-Associated Multiple Autoimmune Disease Susceptibility 4 56
Autoimmune Disease Susceptibility Locus, Chromosome 8-Related 56
Vamas4 56
Ais3 56

External Ids:

OMIM 56 608392

Summaries for Autoimmune Disease 3

MalaCards based summary : Autoimmune Disease 3, also known as autoimmune disease, susceptibility to, 3, is related to vitiligo-associated multiple autoimmune disease susceptibility 6 and vitiligo-associated multiple autoimmune disease susceptibility 1. An important gene associated with Autoimmune Disease 3 is AIS3 (Autoimmune Susceptibility 3 (Vitiligo Specific)). The drugs Methotrexate and Prednisone have been mentioned in the context of this disorder. Affiliated tissues include thyroid and testes.

More information from OMIM: 608392

Related Diseases for Autoimmune Disease 3

Diseases related to Autoimmune Disease 3 via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 12)
# Related Disease Score Top Affiliating Genes
1 vitiligo-associated multiple autoimmune disease susceptibility 6 10.2
2 vitiligo-associated multiple autoimmune disease susceptibility 1 10.2
3 autoimmune disease 2 10.2
4 autoimmune disease 10.1
5 systemic lupus erythematosus 9.7
6 myasthenia gravis 9.7
7 mixed connective tissue disease 9.7
8 liver disease 9.7
9 connective tissue disease 9.7
10 lupus erythematosus 9.7
11 polyarteritis nodosa 9.7
12 cytokine deficiency 9.7

Graphical network of the top 20 diseases related to Autoimmune Disease 3:



Diseases related to Autoimmune Disease 3

Symptoms & Phenotypes for Autoimmune Disease 3

Clinical features from OMIM:

608392

Drugs & Therapeutics for Autoimmune Disease 3

Drugs for Autoimmune Disease 3 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Methotrexate Approved Phase 4 59-05-2, 1959-05-2 126941
2
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
3 Vaccines Phase 4
4 Janus Kinase Inhibitors Phase 4
5
Citalopram Approved 59729-33-8 2771
6 Neurotransmitter Agents
7 Antidepressive Agents
8 Psychotropic Drugs
9 Serotonin Uptake Inhibitors
10 Immunoglobulins
11 Antibodies
12
Serotonin Investigational, Nutraceutical 50-67-9 5202

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Immunogenicity and Efficacy of Subunit Vaccine Against Herpes Zoster in RA Treated With JAK-inhibitors (VACCIMIL-ZOSTER) Recruiting NCT03886038 Phase 4
2 A Neuroimaging and Epigenetic Investigation of Antidepressants in Depression Completed NCT00703742 Escitalopram
3 Relationship Between TLR2 Polymorphism and Pulmonary Tuberculosis Completed NCT00772408
4 Usefulness of Gluten-free Diet in Gluten-genetically Predisposed Subjects Positive to Intestinal-mucosa Anti-transglutaminase Antibodies Active, not recruiting NCT00677495

Search NIH Clinical Center for Autoimmune Disease 3

Genetic Tests for Autoimmune Disease 3

Anatomical Context for Autoimmune Disease 3

MalaCards organs/tissues related to Autoimmune Disease 3:

40
Thyroid, Testes

Publications for Autoimmune Disease 3

Articles related to Autoimmune Disease 3:

(show all 16)
# Title Authors PMID Year
1
Novel vitiligo susceptibility loci on chromosomes 7 (AIS2) and 8 (AIS3), confirmation of SLEV1 on chromosome 17, and their roles in an autoimmune diathesis. 56
14691733 2004
2
Mapping of an autoimmunity susceptibility locus (AIS1) to chromosome 1p31.3-p32.2. 56
11912181 2002
3
A study to evaluate the primary causes associated with Pseudomonas otitis in 60 dogs. 61
29322531 2018
4
Bamboo Nodes of Vocal Folds: A Description of 10 Cases and Review of the Literature. 61
29847817 2018
5
Clinical outcomes of pneumocystis pneumonia from a tertiary care centre in Pakistan. 61
27812050 2016
6
Immunotherapy trial as diagnostic test in evaluating patients with presumed autoimmune gastrointestinal dysmotility. 61
25039328 2014
7
[II. Autoimmune disease: 3. Polyarteritis nodosa and Wegener's granulomatosis]. 61
21702140 2011
8
Pseudo-Pelger-Huët anomaly induced by medications: a clinicopathologic study in comparison with myelodysplastic syndrome-related pseudo-Pelger-Huët anomaly. 61
21228370 2011
9
Cutaneous manifestations in relation to immunologic parameters in a cohort of primary myelodysplastic syndrome patients. 61
18070024 2008
10
Ficolins: structure, function and associated diseases. 61
19025118 2008
11
Cryoglobulinaemia associated with hepatitis C virus: influence of HCV genotypes, HCV-RNA viraemia and HIV coinfection. 61
17875009 2007
12
Thrombotic thrombocytopenic purpura causing rapid unexpected death: value of CD61 immunohistochemical staining in diagnosis. 61
15914300 2005
13
Frontiers of SLE: review of the 5th International Congress of Systemic Lupus Erythematosus, Cancun, Mexico, April 20-25, 1998. 61
10553982 1999
14
Outcome of rheumatoid arthritis and psoriasis following autologous stem cell transplantation for hematologic malignancy. 61
9324027 1997
15
Enhanced susceptibility to amiodarone-induced hypothyroidism in patients with thyroid autoimmune disease. 61
7993156 1994
16
Transfusion-induced immunomodulation and its possible role in cancer recurrence and perioperative bacterial infection. 61
2293502 1990

Variations for Autoimmune Disease 3

Expression for Autoimmune Disease 3

Search GEO for disease gene expression data for Autoimmune Disease 3.

Pathways for Autoimmune Disease 3

GO Terms for Autoimmune Disease 3

Sources for Autoimmune Disease 3

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....