MCID: ATM105
MIFTS: 24

Autoimmune Disease of Peripheral Nervous System

Categories: Immune diseases, Neuronal diseases

Aliases & Classifications for Autoimmune Disease of Peripheral Nervous System

MalaCards integrated aliases for Autoimmune Disease of Peripheral Nervous System:

Name: Autoimmune Disease of Peripheral Nervous System 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0060033

Summaries for Autoimmune Disease of Peripheral Nervous System

Disease Ontology : 12 An autoimmune disease of the nervous system that is the abnormal functioning of the immune system that causes your immune system to produce antibodies or T cells against cells and/or tissues in the peripheral nervous system.

MalaCards based summary : Autoimmune Disease of Peripheral Nervous System is related to autoimmune peripheral neuropathy and guillain-barre syndrome. An important gene associated with Autoimmune Disease of Peripheral Nervous System is HMGA2 (High Mobility Group AT-Hook 2), and among its related pathways/superpathways are Neuroscience and Spinal Cord Injury. Affiliated tissues include t cells and spinal cord, and related phenotypes are behavior/neurological and nervous system

Related Diseases for Autoimmune Disease of Peripheral Nervous System

Diseases in the Peripheral Nervous System Disease family:

Autoimmune Disease of Peripheral Nervous System

Diseases related to Autoimmune Disease of Peripheral Nervous System via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 48)
# Related Disease Score Top Affiliating Genes
1 autoimmune peripheral neuropathy 31.8 CD1E MAG RPS19
2 guillain-barre syndrome 31.2 ALB HCRT HMGA2 MBP PMP2 TNF
3 autoimmune optic neuritis 11.1
4 encephalitozoonosis 10.2 PMP2 TNF
5 central pontine myelinolysis 10.2 MAG MBP
6 meningovascular neurosyphilis 10.2 ALB MBP
7 osteosclerotic myeloma 10.2 MAG TNF
8 chronic graft versus host disease 10.2 ALB TNF
9 multifocal motor neuropathy 10.2 CD1E GLDN
10 chronic inflammatory demyelinating polyradiculoneuropathy 10.2 ALB NFASC
11 miller fisher syndrome 10.2 HMGA2 MAG TNF
12 jejunoileitis 10.1 ALB TNF
13 demyelinating polyneuropathy 10.1 ALB MAG NFASC
14 allergic encephalomyelitis 10.1 MBP MOG
15 tuberculous peritonitis 10.1 ALB TNF
16 balo concentric sclerosis 10.1 MBP MOG
17 panencephalitis, subacute sclerosing 10.1 MBP MOG
18 autoimmune neuropathy 10.1 CD1E HMGA2 MAG NFASC
19 hypersensitivity reaction type iii disease 10.1 ALB TNF
20 transverse myelitis 10.1 MBP TNF
21 tabes dorsalis 10.1 DDX41 MBP
22 transient arthritis 10.1 ALB MBP
23 compartment syndrome 10.1 ALB TNF
24 myelitis 10.0 MBP MOG TNF
25 viral encephalitis 10.0 MBP MOG TNF
26 narcolepsy 1 10.0 HCRT MOG
27 primary progressive multiple sclerosis 10.0 MBP MOG TNF
28 primary bacterial infectious disease 10.0 ALB DDX41 TNF
29 relapsing-remitting multiple sclerosis 10.0 MBP MOG TNF
30 hemorrhagic fever 10.0 ALB TNF
31 von economo's disease 10.0 DDX41 HCRT
32 optic neuritis 10.0 MAG MBP MOG TNF
33 autoimmune disease of central nervous system 10.0 MAG MBP MOG TNF
34 pneumocystosis 9.9 ALB TNF
35 nervous system disease 9.9 ALB MBP MOG TNF
36 multiple sclerosis 9.9 MAG MBP MOG TNF
37 internuclear ophthalmoplegia 9.9 HCRT MBP MOG
38 polyradiculoneuropathy 9.9 ALB MAG MBP NFASC PMP2
39 acute disseminated encephalomyelitis 9.9 HCRT MBP MOG
40 neuromyelitis optica 9.9 HCRT MBP MOG
41 narcolepsy 9.9 HCRT MOG TNF
42 spinal cord disease 9.9 DDX41 MBP MOG TNF
43 demyelinating disease 9.9 GALC MAG MBP MOG TNF
44 neuritis 9.9 MAG MBP MOG PMP2 TNF
45 central nervous system disease 9.8 HCRT MBP MOG TNF
46 autoimmune disease of the nervous system 9.8 DDX41 MAG MBP MOG TNF
47 immune system disease 9.8 ALB DDX41 MBP MOG TNF
48 peripheral nervous system disease 9.8 ALB MAG MBP MOG NFASC TNF

Graphical network of the top 20 diseases related to Autoimmune Disease of Peripheral Nervous System:



Diseases related to Autoimmune Disease of Peripheral Nervous System

Symptoms & Phenotypes for Autoimmune Disease of Peripheral Nervous System

MGI Mouse Phenotypes related to Autoimmune Disease of Peripheral Nervous System:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.61 GALC GLDN HCRT MAG MBP MOG
2 nervous system MP:0003631 9.28 GALC GLDN HCRT MAG MBP MOG

Drugs & Therapeutics for Autoimmune Disease of Peripheral Nervous System

Search Clinical Trials , NIH Clinical Center for Autoimmune Disease of Peripheral Nervous System

Genetic Tests for Autoimmune Disease of Peripheral Nervous System

Anatomical Context for Autoimmune Disease of Peripheral Nervous System

MalaCards organs/tissues related to Autoimmune Disease of Peripheral Nervous System:

41
T Cells, Spinal Cord

Publications for Autoimmune Disease of Peripheral Nervous System

Variations for Autoimmune Disease of Peripheral Nervous System

Expression for Autoimmune Disease of Peripheral Nervous System

Search GEO for disease gene expression data for Autoimmune Disease of Peripheral Nervous System.

Pathways for Autoimmune Disease of Peripheral Nervous System

Pathways related to Autoimmune Disease of Peripheral Nervous System according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.79 HCRT MAG MBP NFASC
2 11.41 MAG MBP TNF
3 9.53 MAG MBP

GO Terms for Autoimmune Disease of Peripheral Nervous System

Cellular components related to Autoimmune Disease of Peripheral Nervous System according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 paranode region of axon GO:0033270 9.16 MAG NFASC
2 myelin sheath GO:0043209 9.02 ALB MAG MBP NFASC PMP2
3 compact myelin GO:0043218 8.96 MAG MBP

Biological processes related to Autoimmune Disease of Peripheral Nervous System according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 heterotypic cell-cell adhesion GO:0034113 9.16 GLDN NFASC
2 transmission of nerve impulse GO:0019226 8.96 MAG NFASC
3 clustering of voltage-gated sodium channels GO:0045162 8.62 GLDN NFASC

Molecular functions related to Autoimmune Disease of Peripheral Nervous System according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lipid binding GO:0008289 9.26 ALB CD1E MAG PMP2
2 fatty acid binding GO:0005504 9.16 ALB PMP2
3 protein binding involved in heterotypic cell-cell adhesion GO:0086080 8.62 GLDN NFASC

Sources for Autoimmune Disease of Peripheral Nervous System

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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