MCID: ATM018
MIFTS: 21

Autoimmune Disease of Urogenital Tract

Categories: Immune diseases

Aliases & Classifications for Autoimmune Disease of Urogenital Tract

MalaCards integrated aliases for Autoimmune Disease of Urogenital Tract:

Name: Autoimmune Disease of Urogenital Tract 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0060049

Summaries for Autoimmune Disease of Urogenital Tract

Disease Ontology : 12 An autoimmune hypersensitivity disease that is the abnormal functioning of the immune system that causes your immune system to produce antibodies or T cells against cells and/or tissues in the urogenital tract.

MalaCards based summary : Autoimmune Disease of Urogenital Tract is related to autoimmune glomerulonephritis and antipyrine metabolism. An important gene associated with Autoimmune Disease of Urogenital Tract is DLAT (Dihydrolipoamide S-Acetyltransferase), and among its related pathways/superpathways are Metabolism and Pyruvate metabolism and Citric Acid (TCA) cycle. Affiliated tissues include t cells and liver.

Related Diseases for Autoimmune Disease of Urogenital Tract

Diseases related to Autoimmune Disease of Urogenital Tract via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 48)
# Related Disease Score Top Affiliating Genes
1 autoimmune glomerulonephritis 11.2
2 antipyrine metabolism 10.3 ALB F2
3 non-a-e hepatitis 10.3 ALB F2
4 hepatoportal sclerosis 10.3 F2 GPT
5 epstein-barr virus hepatitis 10.3 ALB F2
6 fournier gangrene 10.3 ALB F2
7 abdominal tuberculosis 10.3 ALB F2
8 cholestasis, progressive familial intrahepatic, 2 10.3 ABCB4 NR1H4
9 hepatitis d 10.2 F2 GPT
10 splenic disease 10.2 ALB F2
11 nonalcoholic steatohepatitis 10.2 F2 GPT
12 halothane hepatitis 10.2 DLAT OGDH SEPSECS
13 kwashiorkor 10.2 ALB F2 GPT
14 hepatic coma 10.2 ALB F2 GPT
15 biliary atresia 10.2 ALB GPT NR1H4
16 infantile liver failure syndrome 1 10.2 ALB F2 GPT
17 esophageal varix 10.2 ALB F2
18 analbuminemia 10.2 ALB F2 GPT
19 acute liver failure 10.2 ALB F2 GPT
20 hepatitis e 10.2 ALB F2 GPT
21 extrahepatic cholestasis 10.2 ABCB4 GPT
22 bilirubin metabolic disorder 10.2 ALB F2 GPT
23 ascending cholangitis 10.2 ALB F2
24 sclerosing cholangitis 10.2 ABCB4 ALB NR1H4
25 obstructive jaundice 10.2 ALB F2 GPT
26 hepatic encephalopathy 10.2 ALB F2 GPT
27 fascioliasis 10.2 ALB GPT
28 alcoholic hepatitis 10.1 ALB F2 GPT
29 wilson disease 10.1 ALB F2 GPT
30 portal hypertension 10.1 ALB F2 GPT
31 autoimmune hepatitis 10.1 DLAT F2 GPT SEPSECS
32 hepatitis a 10.1 ALB F2 GPT SEPSECS
33 viral hepatitis 10.1 ALB F2 GPT SEPSECS
34 cholelithiasis 10.1 ABCB4 ALB GPT NR1H4
35 hypersplenism 10.0 ALB F2
36 choledocholithiasis 10.0 ABCB4 ALB F2 GPT
37 cholecystitis 10.0 ABCB4 ALB F2 GPT
38 cholestasis 10.0 ABCB4 F2 GPT NR1H4
39 primary biliary cirrhosis 9.9 ABCB4 DBT DLAT LBR PDHX
40 crest syndrome 9.9 CENPB LBR
41 gastrointestinal system disease 9.9 ALB F2 GGT2
42 hepatic tuberculosis 9.8 ALB F2 GGT2 GPT
43 cholangitis 9.8 ABCB4 ALB DLAT F2 GPT SP100
44 hepatitis b 9.8 ALB F2 GPT
45 cholangitis, primary sclerosing 9.7 ABCB4 ALB DLAT GPT NUP210 SEPSECS
46 biliary tract disease 9.6 ABCB4 ALB F2 GGT2 NR1H4
47 liver disease 9.6 ABCB4 ALB DLAT F2 GPT NR1H4
48 bile duct disease 9.5 ABCB4 ALB F2 GGT2 GPT NR1H4

Graphical network of the top 20 diseases related to Autoimmune Disease of Urogenital Tract:



Diseases related to Autoimmune Disease of Urogenital Tract

Symptoms & Phenotypes for Autoimmune Disease of Urogenital Tract

Drugs & Therapeutics for Autoimmune Disease of Urogenital Tract

Search Clinical Trials , NIH Clinical Center for Autoimmune Disease of Urogenital Tract

Genetic Tests for Autoimmune Disease of Urogenital Tract

Anatomical Context for Autoimmune Disease of Urogenital Tract

MalaCards organs/tissues related to Autoimmune Disease of Urogenital Tract:

42
T Cells, Liver

Publications for Autoimmune Disease of Urogenital Tract

Variations for Autoimmune Disease of Urogenital Tract

Expression for Autoimmune Disease of Urogenital Tract

Search GEO for disease gene expression data for Autoimmune Disease of Urogenital Tract.

Pathways for Autoimmune Disease of Urogenital Tract

GO Terms for Autoimmune Disease of Urogenital Tract

Cellular components related to Autoimmune Disease of Urogenital Tract according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitochondrial matrix GO:0005759 9.26 DBT DLAT OGDH PDHX
2 pyruvate dehydrogenase complex GO:0045254 8.62 DLAT PDHX

Biological processes related to Autoimmune Disease of Urogenital Tract according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 glutathione catabolic process GO:0006751 8.96 GGT2 GGTLC3
2 leukotriene D4 biosynthetic process GO:1901750 8.62 GGT2 GGTLC3

Molecular functions related to Autoimmune Disease of Urogenital Tract according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 glutathione hydrolase activity GO:0036374 9.16 GGT2 GGTLC3
2 chromo shadow domain binding GO:0070087 8.96 LBR SP100
3 pyruvate dehydrogenase (NAD+) activity GO:0034604 8.62 DLAT PDHX

Sources for Autoimmune Disease of Urogenital Tract

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....