MCID: ATM018
MIFTS: 20

Autoimmune Disease of Urogenital Tract

Categories: Immune diseases

Aliases & Classifications for Autoimmune Disease of Urogenital Tract

MalaCards integrated aliases for Autoimmune Disease of Urogenital Tract:

Name: Autoimmune Disease of Urogenital Tract 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0060049

Summaries for Autoimmune Disease of Urogenital Tract

Disease Ontology : 12 A hypersensitivity reaction type II disease that is the abnormal functioning of the immune system that causes your immune system to produce antibodies or T cells against cells and/or tissues in the urogenital tract.

MalaCards based summary : Autoimmune Disease of Urogenital Tract is related to colorado tick fever and selective igg deficiency disease. An important gene associated with Autoimmune Disease of Urogenital Tract is DLAT (Dihydrolipoamide S-Acetyltransferase), and among its related pathways/superpathways are Pyruvate metabolism and Citric Acid (TCA) cycle and Glyoxylate metabolism and glycine degradation. Affiliated tissues include t cells, and related phenotype is renal/urinary system.

Related Diseases for Autoimmune Disease of Urogenital Tract

Diseases related to Autoimmune Disease of Urogenital Tract via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 120)
# Related Disease Score Top Affiliating Genes
1 colorado tick fever 10.9 ALB CD40LG
2 selective igg deficiency disease 10.9 CD40LG CD79A
3 c1q nephropathy 10.9 CD40LG CD79A
4 meningovascular neurosyphilis 10.9 CD40LG CD79A
5 alpha chain disease 10.9 CD40LG CD79A
6 brill-zinsser disease 10.9 CD40LG CD79A
7 exudative glomerulonephritis 10.9 CD40LG CD79A
8 salpingo-oophoritis 10.9 CD40LG CD79A
9 early yaws 10.8 CD40LG CD79A
10 plasmodium malariae malaria 10.8 ALB CD40LG
11 ventilation pneumonitis 10.8 CD40LG CD79A
12 chronic interstitial cystitis 10.8 CD40LG CD79A
13 axillary adenitis 10.8 CD40LG CD79A
14 cryofibrinogenemia 10.8 CD40LG CD79A
15 trichostrongyloidiasis 10.8 CD40LG CD79A
16 subacute bacterial endocarditis 10.8 CD40LG CD79A
17 heterophyiasis 10.8 CD40LG CD79A
18 immunoglobulin g deficiency 10.8 CD40LG CD79A
19 fournier gangrene 10.8 ALB CD40LG
20 orbital granuloma 10.8 CD40LG CD79A
21 transient hypogammaglobulinemia of infancy 10.8 CD40LG CD79A
22 hyperglobulinemic purpura 10.8 CD40LG CD79A
23 gastroduodenitis 10.8 CD40LG CD79A
24 bacterial conjunctivitis 10.8 CD40LG CD79A
25 ostertagiasis 10.8 ALB CD79A
26 heavy chain disease 10.8 CD40LG CD79A
27 ophthalmia neonatorum 10.8 CD40LG CD79A
28 dermatitis, atopic, 3 10.8 ALB CD79A
29 immunoglobulin a deficiency 1 10.8 CD40LG CD79A
30 parotid disease 10.8 CD40LG CD79A
31 cerebral arteritis 10.8 CD40LG CD79A
32 selective immunoglobulin deficiency disease 10.8 CD40LG CD79A
33 geniculate herpes zoster 10.7 CD40LG CD79A
34 erythema elevatum diutinum 10.7 CD40LG CD79A
35 sporotrichosis 10.7 CD40LG CD79A
36 fallopian tube disease 10.7 CD40LG CD79A
37 hyperimmunoglobulin syndrome 10.7 CD40LG CD79A
38 congenital syphilis 10.7 CD40LG CD79A
39 polyclonal hypergammaglobulinemia 10.7 CD40LG CD79A
40 monoclonal paraproteinemia 10.7 CD40LG CD79A
41 salpingitis 10.7 CD40LG CD79A
42 dysgammaglobulinemia 10.7 CD40LG CD79A
43 congenital hypogammaglobulinemia 10.7 CD40LG CD79A
44 acute maxillary sinusitis 10.7 CD40LG CD79A
45 autoimmune hepatitis 10.7 CD40LG DLAT SEPSECS
46 chronic polyneuropathy 10.7 CD40LG CD79A
47 root caries 10.6 ALB CD79A
48 spinocerebellar ataxia, autosomal recessive 10 10.6 CD40LG CD79A
49 parasitic ichthyosporea infectious disease 10.6 CD40LG CD79A
50 cd40 ligand deficiency 10.6 CD40LG CD79A

Graphical network of the top 20 diseases related to Autoimmune Disease of Urogenital Tract:



Diseases related to Autoimmune Disease of Urogenital Tract

Symptoms & Phenotypes for Autoimmune Disease of Urogenital Tract

MGI Mouse Phenotypes related to Autoimmune Disease of Urogenital Tract:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 renal/urinary system MP:0005367 9.17 ALB CD40LG CD79A DBT LBR SCHIP1

Drugs & Therapeutics for Autoimmune Disease of Urogenital Tract

Search Clinical Trials , NIH Clinical Center for Autoimmune Disease of Urogenital Tract

Genetic Tests for Autoimmune Disease of Urogenital Tract

Anatomical Context for Autoimmune Disease of Urogenital Tract

MalaCards organs/tissues related to Autoimmune Disease of Urogenital Tract:

41
T Cells

Publications for Autoimmune Disease of Urogenital Tract

Variations for Autoimmune Disease of Urogenital Tract

Expression for Autoimmune Disease of Urogenital Tract

Search GEO for disease gene expression data for Autoimmune Disease of Urogenital Tract.

Pathways for Autoimmune Disease of Urogenital Tract

GO Terms for Autoimmune Disease of Urogenital Tract

Cellular components related to Autoimmune Disease of Urogenital Tract according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitochondrial matrix GO:0005759 9.26 DBT DLAT OGDH PDHX
2 pyruvate dehydrogenase complex GO:0045254 8.62 DLAT PDHX

Biological processes related to Autoimmune Disease of Urogenital Tract according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of acetyl-CoA biosynthetic process from pyruvate GO:0010510 8.96 DLAT PDHX
2 cellular nitrogen compound metabolic process GO:0034641 8.92 DBT DLAT OGDH PDHX

Molecular functions related to Autoimmune Disease of Urogenital Tract according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 pyruvate dehydrogenase (NAD+) activity GO:0034604 8.96 DLAT PDHX
2 chromo shadow domain binding GO:0070087 8.62 LBR SP100

Sources for Autoimmune Disease of Urogenital Tract

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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