MCID: ATM101
MIFTS: 46

Autoimmune Gastritis

Categories: Gastrointestinal diseases, Immune diseases, Infectious diseases

Aliases & Classifications for Autoimmune Gastritis

MalaCards integrated aliases for Autoimmune Gastritis:

Name: Autoimmune Gastritis 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0040090

Summaries for Autoimmune Gastritis

Disease Ontology : 12 An autoimmune disease of gastrointestinal tract that is located in the stomach.

MalaCards based summary : Autoimmune Gastritis is related to hepatitis a and autoimmune disease. An important gene associated with Autoimmune Gastritis is IL4 (Interleukin 4), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Immunoglobulins and Antibodies have been mentioned in the context of this disorder. Affiliated tissues include the stomach, t cells and thyroid, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Autoimmune Gastritis

Diseases in the Gastritis family:

Autoimmune Gastritis Viral Gastritis
Bacterial Gastritis

Diseases related to Autoimmune Gastritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 257)
# Related Disease Score Top Affiliating Genes
1 hepatitis a 29.9 IFNG IL10 TNF
2 autoimmune disease 29.7 IFNG IL10 IL2 IL4 TNF
3 colitis 29.7 IFNG IL10 IL2 IL4 TNF
4 systemic lupus erythematosus 29.4 IFNG IL10 IL2 IL4 TGFB1 TNF
5 autoimmune atrophic gastritis 11.2
6 gastritis 10.9
7 opisthorchiasis 10.4 IL4 TNF
8 farmer's lung 10.4 IL2 TNF
9 burning mouth syndrome 10.4 IL2 TNF
10 streptococcal toxic-shock syndrome 10.4 IL2 TNF
11 autoimmune vasculitis 10.4 IL2 IL4
12 angiostrongyliasis 10.4 IL2 IL4
13 cow milk allergy 10.4 IL10 TNF
14 trachoma 10.4 IL10 TNF
15 trichuriasis 10.4 IL10 TNF
16 jak3-deficient severe combined immunodeficiency 10.4 IL2 IL4
17 transient hypogammaglobulinemia 10.4 IL10 TNF
18 mucocutaneous leishmaniasis 10.4 IL10 TNF
19 idiopathic achalasia 10.4 IL10 TNF
20 retinitis pigmentosa 22 10.4 IL10 IL4
21 apple allergy 10.4 IL10 IL4
22 beta-lactam allergy 10.4 IL10 IL4
23 eosinophilic meningitis 10.4 IL10 IL4
24 filarial elephantiasis 10.4 IL10 IL4
25 trichosporonosis 10.4 IFNG TNF
26 microscopic colitis 10.4 IFNG TNF
27 meconium aspiration syndrome 10.4 IFNG TNF
28 retinitis pigmentosa 44 10.4 IL10 IL2
29 central nervous system vasculitis 10.4 IFNG TNF
30 tuberculous peritonitis 10.4 IFNG TNF
31 miliary tuberculosis 10.4 IFNG TNF
32 b-cell growth factor 10.4 IFNG IL4
33 chronic beryllium disease 10.4 IFNG TNF
34 penicillin allergy 10.4 IFNG IL4
35 crustacean allergy 10.4 IFNG IL4
36 toxic oil syndrome 10.4 IFNG IL4
37 berylliosis 10.4 IFNG IL2
38 multicentric castleman disease 10.4 IFNG IL10
39 fungal meningitis 10.4 IFNG IL10
40 sporotrichosis 10.4 IFNG IL10
41 pericardial tuberculosis 10.4 IFNG IL10
42 oral tuberculosis 10.4 IL2 TNF
43 laryngitis 10.4 TGFB1 TNF
44 posterior urethral valves 10.4 TGFB1 TNF
45 punctate inner choroidopathy 10.3 IL10 TNF
46 strongyloidiasis 10.3 IFNG TGFB1
47 eosinophilia-myalgia syndrome 10.3 IFNG TGFB1
48 recurrent respiratory papillomatosis 10.3 EGFR IL2
49 virus associated hemophagocytic syndrome 10.3 IL2 IL4
50 pernicious anemia 10.2

Graphical network of the top 20 diseases related to Autoimmune Gastritis:



Diseases related to Autoimmune Gastritis

Symptoms & Phenotypes for Autoimmune Gastritis

GenomeRNAi Phenotypes related to Autoimmune Gastritis according to GeneCards Suite gene sharing:

27 (show all 39)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-102 9.99 KIR3DL3
2 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.99 TGFB1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-115 9.99 KIR2DS1
4 Increased shRNA abundance (Z-score > 2) GR00366-A-116 9.99 TGFB1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-118 9.99 KIR2DS1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-120 9.99 TGFB1
7 Increased shRNA abundance (Z-score > 2) GR00366-A-122 9.99 KIR2DS1 KIR3DL3
8 Increased shRNA abundance (Z-score > 2) GR00366-A-123 9.99 KIR2DS1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-140 9.99 KIR2DS1 KIR3DL3 TGFB1
10 Increased shRNA abundance (Z-score > 2) GR00366-A-143 9.99 TGFB1
11 Increased shRNA abundance (Z-score > 2) GR00366-A-149 9.99 KIR3DL3
12 Increased shRNA abundance (Z-score > 2) GR00366-A-152 9.99 KIR3DL3
13 Increased shRNA abundance (Z-score > 2) GR00366-A-156 9.99 KIR3DL3
14 Increased shRNA abundance (Z-score > 2) GR00366-A-164 9.99 KIR2DS1
15 Increased shRNA abundance (Z-score > 2) GR00366-A-168 9.99 KIR3DL3
16 Increased shRNA abundance (Z-score > 2) GR00366-A-169 9.99 TGFB1
17 Increased shRNA abundance (Z-score > 2) GR00366-A-172 9.99 KIR2DS1
18 Increased shRNA abundance (Z-score > 2) GR00366-A-178 9.99 TGFB1
19 Increased shRNA abundance (Z-score > 2) GR00366-A-186 9.99 KIR3DL3
20 Increased shRNA abundance (Z-score > 2) GR00366-A-190 9.99 KIR3DL3
21 Increased shRNA abundance (Z-score > 2) GR00366-A-195 9.99 KIR2DS1
22 Increased shRNA abundance (Z-score > 2) GR00366-A-196 9.99 KIR2DS1 KIR3DL3
23 Increased shRNA abundance (Z-score > 2) GR00366-A-198 9.99 KIR2DS1 TGFB1
24 Increased shRNA abundance (Z-score > 2) GR00366-A-199 9.99 KIR2DS1 KIR3DL3
25 Increased shRNA abundance (Z-score > 2) GR00366-A-201 9.99 KIR3DL3
26 Increased shRNA abundance (Z-score > 2) GR00366-A-202 9.99 KIR2DS1 KIR3DL3
27 Increased shRNA abundance (Z-score > 2) GR00366-A-205 9.99 KIR3DL3
28 Increased shRNA abundance (Z-score > 2) GR00366-A-21 9.99 KIR2DS1
29 Increased shRNA abundance (Z-score > 2) GR00366-A-31 9.99 KIR3DL3
30 Increased shRNA abundance (Z-score > 2) GR00366-A-32 9.99 KIR2DS1
31 Increased shRNA abundance (Z-score > 2) GR00366-A-35 9.99 TGFB1
32 Increased shRNA abundance (Z-score > 2) GR00366-A-56 9.99 TGFB1
33 Increased shRNA abundance (Z-score > 2) GR00366-A-73 9.99 KIR2DS1 KIR3DL3
34 Increased shRNA abundance (Z-score > 2) GR00366-A-77 9.99 TGFB1
35 Increased shRNA abundance (Z-score > 2) GR00366-A-79 9.99 KIR3DL3
36 Increased shRNA abundance (Z-score > 2) GR00366-A-81 9.99 KIR2DS1 KIR3DL3
37 Increased shRNA abundance (Z-score > 2) GR00366-A-93 9.99 KIR2DS1 KIR3DL3
38 Decreased viability with paclitaxel GR00179-A-1 9.61 EGFR TGFB1 IL10
39 Decreased viability with paclitaxel GR00179-A-3 9.61 EGFR TGFB1

MGI Mouse Phenotypes related to Autoimmune Gastritis:

47 (show all 12)
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 10.1 EGF EGFR IFNG IL10 IL2 IL4
2 endocrine/exocrine gland MP:0005379 10.08 EGF EGFR IFNG IL10 IL2 IL4
3 growth/size/body region MP:0005378 10.06 EGF EGFR IFNG IL10 IL2 IL4
4 immune system MP:0005387 10.03 EGF EGFR IFNG IL10 IL2 IL4
5 craniofacial MP:0005382 9.99 EGFR IFNG IL10 IL4 TGFB1 TNF
6 integument MP:0010771 9.95 EGF EGFR IFNG IL10 IL4 TGFB1
7 liver/biliary system MP:0005370 9.91 EGFR IFNG IL10 IL2 IL4 TGFB1
8 neoplasm MP:0002006 9.8 EGFR IFNG IL10 IL2 TGFB1 TNF
9 reproductive system MP:0005389 9.76 EGF EGFR IFNG IL10 IL2 IL4
10 no phenotypic analysis MP:0003012 9.73 EGFR IFNG IL10 IL2 IL4 TNF
11 respiratory system MP:0005388 9.5 EGFR IFNG IL10 IL2 IL4 TGFB1
12 vision/eye MP:0005391 9.23 EGF EGFR IFNG IL10 IL2 IL4

Drugs & Therapeutics for Autoimmune Gastritis

Drugs for Autoimmune Gastritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Immunoglobulins
2 Antibodies
3 Immunologic Factors
4 Antibodies, Antinuclear

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Autoimmune Diseases And Serum Anti-Nuclear Antibodies Positivity In Non-Celiac Wheat Sensitivity Patients Completed NCT02248545

Search NIH Clinical Center for Autoimmune Gastritis

Genetic Tests for Autoimmune Gastritis

Anatomical Context for Autoimmune Gastritis

The Foundational Model of Anatomy Ontology organs/tissues related to Autoimmune Gastritis:

20
The Stomach

MalaCards organs/tissues related to Autoimmune Gastritis:

42
T Cells, Thyroid, Liver, Bone, Heart, Bone Marrow, Thymus

Publications for Autoimmune Gastritis

Articles related to Autoimmune Gastritis:

(show top 50) (show all 167)
# Title Authors Year
1
Insights into Pediatric Autoimmune Gastritis: Is There a Role for Helicobacter Pylori Infection? ( 30664567 )
2019
2
Subacute Combined Degeneration, Pernicious Anemia and Gastric Neuroendocrine Tumor Occured Simultaneously Caused by Autoimmune Gastritis. ( 30740042 )
2019
3
Utility of a laboratory score in the prediction of altered autonomic nervous system function in autoimmune gastritis. ( 29391305 )
2018
4
High incidence of autoimmune gastritis in patients misdiagnosed with two or more failures of H. pylori eradication. ( 29920721 )
2018
5
Utility of a laboratory score in the prediction of gastric emptying in autoimmune gastritis patients. ( 28738729 )
2018
6
The Relations Among Serum Ghrelin, Motilin and Gastric Emptying and Autonomic Function in Autoimmune Gastritis. ( 29753372 )
2018
7
Autoimmune Gastritis in the Pediatric Age: An Underestimated Condition Report of Two Cases and Review. ( 29765934 )
2018
8
Deficiency of micronutrients in patients affected by chronic atrophic autoimmune gastritis: A single-institution observational study. ( 30236765 )
2018
9
Iron deficiency workup reveals high incidence of autoimmune gastritis with parietal cell antibody as reliable screening test. ( 30502855 )
2018
10
Upper gastrointestinal symptoms in autoimmune gastritis: A cross-sectional study. ( 28072728 )
2017
11
Micronutrient deficiencies in patients with chronic atrophic autoimmune gastritis: A review. ( 28216963 )
2017
12
Autoimmune gastritis: relationships with anemia and Helicobacter pylori status. ( 28276835 )
2017
13
Helicobacter pylori and necessary rationale for autoimmune gastritis. ( 28290721 )
2017
14
Hashimoto's Thyroiditis and Autoimmune Gastritis. ( 28491051 )
2017
15
Multiplex autoantibody detection for autoimmune liver diseases and autoimmune gastritis. ( 28522403 )
2017
16
Autoimmune gastritis: assessment of OLGA and OLGIM staging systems. ( 29492930 )
2017
17
Factors associated with elevated serum chromogranin A levels in patients with autoimmune gastritis. ( 27852542 )
2016
18
Revisiting autoimmune gastritis in children and adolescents with type 1 diabetes. ( 28004477 )
2016
19
Polyautoimmunity in autoimmune gastritis. ( 27085391 )
2016
20
Relationships between autonomic nerve function and gastric emptying in patients with autoimmune gastritis. ( 27059861 )
2016
21
Differences between older and young patients with autoimmune gastritis. ( 27444719 )
2016
22
Assessment of Gastric Emptying in Patients with Autoimmune Gastritis. ( 26725066 )
2016
23
Oxyntic gastric atrophy in Helicobacter pylori gastritis is distinct from autoimmune gastritis. ( 26729016 )
2016
24
Induction of autoimmune gastritis by neonatal thymectomy requires autoantibodies and is prevented by anti-FcγR antibodies. ( 26748859 )
2016
25
Regulatory T Cells Control Th2-Dominant Murine Autoimmune Gastritis. ( 27259856 )
2016
26
Autoimmune gastritis. ( 27671008 )
2016
27
Malignant transformation of a gastric hyperplastic polyp in a context of Helicobacter pylori-negative autoimmune gastritis: a case report. ( 27729029 )
2016
28
Autoimmune gastritis: Pathologist's viewpoint. ( 26576102 )
2015
29
Diminished salivary epidermal growth factor secretion: a link between SjAPgren's syndrome and autoimmune gastritis? ( 26399281 )
2015
30
Autoimmune gastritis in autoimmune thyroid disease. ( 25648057 )
2015
31
Single nucleotide polymorphisms related to vitamin B12 serum levels in autoimmune gastritis patients with or without pernicious anaemia. ( 25681243 )
2015
32
Autoimmune gastritis among T1D individuals - important association? ( 27776198 )
2015
33
Mean platelet volume and red cell distribution width in autoimmune gastritis: Confounding factors should be considered. ( 24433174 )
2014
34
Autoimmune gastritis presenting as iron deficiency anemia in childhood. ( 25400463 )
2014
35
Diagnosis and classification of autoimmune gastritis. ( 24424193 )
2014
36
Dominant trait linked to chromosome 1 in DBA/2 mice for the resistance to autoimmune gastritis appears in bone marrow cells. ( 24770641 )
2014
37
A case of rheumatic valvular heart disease and autoimmune gastritis. ( 25535234 )
2014
38
Interleukin-21 and tumor necrosis factor-I+ are critical for the development of autoimmune gastritis in mice. ( 23425147 )
2013
39
Hepatitis C virus antibody positivity may not be associated with hepatitis C infection in patients with autoimmune gastritis. ( 23011039 )
2013
40
Are patients with autoimmune thyroid disease and autoimmune gastritis at risk for Gastric Neuroendocrine Tumours type 1? ( 24118101 )
2013
41
The predictive value of mean platelet volume, plateletcrit and red cell distribution width in the differentiation of autoimmune gastritis patients with and without type I gastric carcinoid tumors. ( 24175991 )
2013
42
Autoimmune gastritis: novel clues to histological diagnosis. ( 23277173 )
2013
43
Autoimmune gastritis mediated by CD4+ T cells promotes the development of gastric cancer. ( 23378345 )
2013
44
Features of the atrophic corpus mucosa in three cases of autoimmune gastritis revealed by magnifying endoscopy. ( 22811721 )
2012
45
Clinical profiles, endoscopic and laboratory features and associated factors in patients with autoimmune gastritis. ( 22710370 )
2012
46
Increased susceptibility to autoimmune gastritis in thymic stromal lymphopoietin receptor-deficient mice. ( 22124119 )
2012
47
Effect of endogenous hypergastrinemia on gallbladder volume and ejection fraction in patients with autoimmune gastritis. ( 23060399 )
2012
48
Clinical usefulness of the serological gastric biopsy for the diagnosis of chronic autoimmune gastritis. ( 23251219 )
2012
49
Both IFN-I^ and IL-17 are required for the development of severe autoimmune gastritis. ( 22777705 )
2012
50
Cutting edge issues in autoimmune gastritis. ( 21174235 )
2012

Variations for Autoimmune Gastritis

Expression for Autoimmune Gastritis

Search GEO for disease gene expression data for Autoimmune Gastritis.

Pathways for Autoimmune Gastritis

Pathways related to Autoimmune Gastritis according to GeneCards Suite gene sharing:

(show top 50) (show all 79)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.94 EGF EGFR IFNG IL10 IL2 IL4
2
Show member pathways
13.76 EGF EGFR IL10 IL2 IL4 TGFB1
3
Show member pathways
13.61 EGFR IFNG IL10 IL2 IL4 TGFB1
4
Show member pathways
13.49 EGF EGFR IFNG IL10 IL2 IL4
5
Show member pathways
13.38 EGF EGFR IL10 IL2 IL4 TGFB1
6
Show member pathways
13.32 EGF EGFR IFNG IL10 IL2 IL4
7
Show member pathways
13.27 EGF EGFR IL10 IL2 IL4 TGFB1
8
Show member pathways
13.2 EGF EGFR IL2 TGFB1 TNF
9
Show member pathways
13.17 EGF EGFR IFNG IL2 IL4 TNF
10
Show member pathways
13.14 IFNG IL10 IL2 TGFB1 TNF
11
Show member pathways
13.01 EGF EGFR IL2 IL4 TGFB1
12
Show member pathways
12.95 EGF EGFR IL2 IL4 TNF
13 12.84 EGF EGFR IFNG IL2 IL4 TGFB1
14 12.71 EGF EGFR TGFB1 TNF
15
Show member pathways
12.71 EGF EGFR IL2 TGFB1 TNF
16
Show member pathways
12.66 IFNG IL10 IL2 IL4 KIR2DS1 KIR3DL3
17
Show member pathways
12.64 EGF EGFR IFNG TNF
18
Show member pathways
12.64 IFNG IL10 IL2 IL4 TNF
19
Show member pathways
12.6 EGFR IFNG IL10 IL2 TNF
20
Show member pathways
12.59 IFNG IL10 IL2 IL4 TGFB1 TNF
21 12.58 IFNG IL10 IL2 IL4 TNF
22
Show member pathways
12.53 IFNG IL2 IL4 TNF
23
Show member pathways
12.53 IFNG IL2 IL4 KIR2DS1 TNF
24
Show member pathways
12.4 IFNG IL10 IL2 IL4 TGFB1 TNF
25
Show member pathways
12.39 EGF EGFR IFNG IL10 IL2 IL4
26
Show member pathways
12.34 EGF EGFR IL2 TGFB1
27
Show member pathways
12.34 IFNG IL2 IL4 TNF
28
Show member pathways
12.29 IFNG IL10 IL4 TGFB1 TNF
29 12.25 IFNG IL10 TGFB1 TNF
30 12.21 EGF EGFR IFNG TGFB1 TNF
31
Show member pathways
12.16 IL10 IL2 TNF
32
Show member pathways
12.14 IFNG IL4 TNF
33
Show member pathways
12.12 EGF TGFB1 TNF
34
Show member pathways
12.12 EGF EGFR IL10 TGFB1
35
Show member pathways
12.12 EGFR IFNG IL10 IL2 IL4 TGFB1
36
Show member pathways
12.08 EGF EGFR TGFB1
37
Show member pathways
12.08 IFNG IL10 IL2 TGFB1 TNF
38 12.02 IFNG TGFB1 TNF
39 12.02 IL10 IL4 TGFB1 TNF
40
Show member pathways
12.01 IFNG IL4 TNF
41 12 IFNG IL10 IL2 IL4 TNF
42
Show member pathways
11.96 IFNG IL2 IL4
43
Show member pathways
11.96 EGF EGFR IFNG IL10 IL2 IL4
44 11.93 IFNG IL10 TGFB1 TNF
45 11.9 EGF EGFR IFNG
46 11.9 EGF EGFR IFNG IL10 IL2
47 11.86 IFNG TGFB1 TNF
48 11.84 IFNG TGFB1 TNF
49
Show member pathways
11.81 IFNG IL2 IL4 TNF
50 11.8 IFNG IL2 IL4

GO Terms for Autoimmune Gastritis

Cellular components related to Autoimmune Gastritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.56 EGF EGFR IFNG IL10 IL2 IL4
2 extracellular space GO:0005615 9.23 EGF EGFR IFNG IL10 IL2 IL4

Biological processes related to Autoimmune Gastritis according to GeneCards Suite gene sharing:

(show all 49)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription, DNA-templated GO:0045893 9.93 EGF EGFR IL10 IL4 TGFB1 TNF
2 positive regulation of gene expression GO:0010628 9.92 EGF IFNG IL4 TGFB1 TNF
3 regulation of cell proliferation GO:0042127 9.88 EGFR TGFB1 TNF
4 positive regulation of protein kinase B signaling GO:0051897 9.84 EGF EGFR TGFB1 TNF
5 response to organic substance GO:0010033 9.83 IL10 TGFB1 TNF
6 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.83 EGFR TGFB1 TNF
7 cytokine-mediated signaling pathway GO:0019221 9.83 IL10 IL2 IL4 TGFB1 TNF
8 positive regulation of inflammatory response GO:0050729 9.82 EGFR IL2 TNF
9 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.81 IFNG IL2 IL4
10 regulation of signaling receptor activity GO:0010469 9.8 IFNG IL10 IL2 IL4 TGFB1 TNF
11 positive regulation of protein localization to plasma membrane GO:1903078 9.78 EGFR IFNG TNF
12 MAPK cascade GO:0000165 9.77 EGF EGFR IL2 TGFB1 TNF
13 epidermal growth factor receptor signaling pathway GO:0007173 9.76 EGF EGFR TGFB1
14 extrinsic apoptotic signaling pathway GO:0097191 9.75 IFNG TGFB1 TNF
15 negative regulation of myoblast differentiation GO:0045662 9.71 TGFB1 TNF
16 positive regulation of osteoclast differentiation GO:0045672 9.7 IFNG TNF
17 positive regulation of T cell differentiation GO:0045582 9.7 IL2 IL4
18 myeloid dendritic cell differentiation GO:0043011 9.7 IL4 TGFB1
19 regulation of peptidyl-tyrosine phosphorylation GO:0050730 9.69 EGF EGFR
20 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.69 IFNG TNF
21 positive regulation of superoxide anion generation GO:0032930 9.69 EGFR TGFB1
22 liver regeneration GO:0097421 9.69 EGFR IL10 TGFB1
23 negative regulation of growth of symbiont in host GO:0044130 9.68 IL10 TNF
24 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.68 IL10 TNF
25 positive regulation of interleukin-17 production GO:0032740 9.68 IL2 TGFB1
26 negative regulation of interleukin-17 production GO:0032700 9.68 IFNG TGFB1
27 positive regulation of regulatory T cell differentiation GO:0045591 9.67 IL2 TGFB1
28 astrocyte activation GO:0048143 9.67 EGFR TNF
29 positive regulation of isotype switching to IgG isotypes GO:0048304 9.67 IL2 IL4
30 salivary gland morphogenesis GO:0007435 9.66 EGFR TGFB1
31 positive regulation of production of miRNAs involved in gene silencing by miRNA GO:1903800 9.65 EGFR TGFB1
32 endothelial cell apoptotic process GO:0072577 9.65 IL10 TNF
33 positive regulation of protein complex assembly GO:0031334 9.65 IFNG TGFB1 TNF
34 positive regulation of MHC class II biosynthetic process GO:0045348 9.64 IL10 IL4
35 negative regulation of cytokine secretion involved in immune response GO:0002740 9.63 IL10 TNF
36 negative regulation of ERBB signaling pathway GO:1901185 9.62 EGF EGFR
37 regulation of isotype switching GO:0045191 9.6 IL10 IL4
38 type 2 immune response GO:0042092 9.59 IL10 IL4
39 regulation of regulatory T cell differentiation GO:0045589 9.58 IFNG IL2 TGFB1
40 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.57 IFNG TNF
41 positive regulation of mononuclear cell migration GO:0071677 9.56 TGFB1 TNF
42 positive regulation of MAP kinase activity GO:0043406 9.56 EGF EGFR TGFB1 TNF
43 receptor biosynthetic process GO:0032800 9.55 IL10 TNF
44 positive regulation of protein phosphorylation GO:0001934 9.55 EGFR IFNG IL2 TGFB1 TNF
45 positive regulation of vitamin D biosynthetic process GO:0060557 9.49 IFNG TNF
46 negative regulation of mitotic cell cycle GO:0045930 9.26 EGFR IL10 TGFB1 TNF
47 immune response GO:0006955 9.17 IFNG IL10 IL2 IL4 KIR2DS1 KIR3DS1
48 positive regulation of transcription by RNA polymerase II GO:0045944 10.09 EGFR IL10 IL2 IL4 TGFB1 TNF
49 positive regulation of cell proliferation GO:0008284 10.01 EGF EGFR IFNG IL2 TGFB1

Molecular functions related to Autoimmune Gastritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.35 EGF IL10 IL2 IL4 TGFB1
2 Ras guanyl-nucleotide exchange factor activity GO:0005088 9.33 EGF EGFR IL2
3 cytokine activity GO:0005125 9.1 IFNG IL10 IL2 IL4 TGFB1 TNF

Sources for Autoimmune Gastritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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