MCID: ATM101
MIFTS: 47

Autoimmune Gastritis

Categories: Gastrointestinal diseases, Immune diseases, Infectious diseases

Aliases & Classifications for Autoimmune Gastritis

MalaCards integrated aliases for Autoimmune Gastritis:

Name: Autoimmune Gastritis 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0040090

Summaries for Autoimmune Gastritis

Disease Ontology : 12 An autoimmune disease of gastrointestinal tract that is located in the stomach.

MalaCards based summary : Autoimmune Gastritis is related to hepatitis a and heart disease. An important gene associated with Autoimmune Gastritis is IL4 (Interleukin 4), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Immunologic Factors and Antibodies, Antinuclear have been mentioned in the context of this disorder. Affiliated tissues include t cells, thyroid and bone, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Autoimmune Gastritis

Diseases in the Gastritis family:

Autoimmune Gastritis Viral Gastritis
Bacterial Gastritis

Diseases related to Autoimmune Gastritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 362)
# Related Disease Score Top Affiliating Genes
1 hepatitis a 30.1 IFNG IL10 TNF
2 heart disease 29.1 IL10 IL1B IL6 TNF
3 diabetes mellitus 28.7 IFNG IL1B IL2 IL6 TNF
4 autoimmune disease 28.5 IFNG IL10 IL1B IL2 IL4 IL6
5 colitis 28.5 IFNG IL10 IL1B IL2 IL4 IL6
6 systemic lupus erythematosus 28.1 IFNG IL10 IL1B IL2 IL4 IL6
7 autoimmune atrophic gastritis 11.2
8 gastritis 11.0
9 farmer's lung 10.4 IL2 TNF
10 angiostrongyliasis 10.4 IL2 IL4
11 oral tuberculosis 10.4 IL2 TNF
12 cow milk allergy 10.4 IL10 TNF
13 trachoma 10.4 IL10 TNF
14 choroiditis 10.4 IL10 TNF
15 retinitis pigmentosa 22 10.4 IL10 IL4
16 trichuriasis 10.4 IL10 TNF
17 apple allergy 10.4 IL10 IL4
18 beta-lactam allergy 10.4 IL10 IL4
19 transient hypogammaglobulinemia 10.4 IL10 TNF
20 eosinophilic meningitis 10.4 IL10 IL4
21 mucocutaneous leishmaniasis 10.4 IL10 TNF
22 virus associated hemophagocytic syndrome 10.4 IL2 IL4
23 jak3-deficient severe combined immunodeficiency 10.4 IL2 IL4
24 filarial elephantiasis 10.4 IL10 IL4
25 trichosporonosis 10.4 IFNG TNF
26 idiopathic achalasia 10.4 IL10 TNF
27 microscopic colitis 10.4 IFNG TNF
28 multifocal choroiditis 10.4 IL10 TNF
29 retinitis pigmentosa 44 10.4 IL10 IL2
30 punctate inner choroidopathy 10.4 IL10 TNF
31 penicillin allergy 10.4 IFNG IL4
32 crustacean allergy 10.4 IFNG IL4
33 miliary tuberculosis 10.4 IFNG TNF
34 soft tissue sarcoma 10.4 IFNG TNF
35 chronic beryllium disease 10.4 IFNG TNF
36 variola major 10.4 IFNG IL2
37 berylliosis 10.4 IFNG IL2
38 cephalosporin allergy 10.4 IFNG IL10
39 fungal meningitis 10.4 IFNG IL10
40 fixed drug eruption 10.4 IFNG IL2
41 sporotrichosis 10.4 IFNG IL10
42 pericardial tuberculosis 10.4 IFNG IL10
43 inflammatory bowel disease 25, autosomal recessive 10.3 IL10 TGFB1
44 actinic prurigo 10.3 IL1B TNF
45 retinitis pigmentosa 60 10.3 IL1B TNF
46 kashin-beck disease 10.3 IL1B TNF
47 burns 10.3 IL1B TNF
48 strongyloidiasis 10.3 IFNG TGFB1
49 juvenile myasthenia gravis 10.3 IL10 TGFB1
50 jejunoileitis 10.3 IL1B TNF

Graphical network of the top 20 diseases related to Autoimmune Gastritis:



Diseases related to Autoimmune Gastritis

Symptoms & Phenotypes for Autoimmune Gastritis

GenomeRNAi Phenotypes related to Autoimmune Gastritis according to GeneCards Suite gene sharing:

27 (show top 50) (show all 56)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-100 10.66 IL10 IL1B
2 Increased shRNA abundance (Z-score > 2) GR00366-A-102 10.66 KIR3DL3 IL1B
3 Increased shRNA abundance (Z-score > 2) GR00366-A-105 10.66 TGFB1
4 Increased shRNA abundance (Z-score > 2) GR00366-A-113 10.66 IL10
5 Increased shRNA abundance (Z-score > 2) GR00366-A-115 10.66 KIR2DS1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-116 10.66 TGFB1 IL1B
7 Increased shRNA abundance (Z-score > 2) GR00366-A-118 10.66 KIR2DS1
8 Increased shRNA abundance (Z-score > 2) GR00366-A-120 10.66 TGFB1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-122 10.66 KIR2DS1 KIR3DL3
10 Increased shRNA abundance (Z-score > 2) GR00366-A-123 10.66 KIR2DS1
11 Increased shRNA abundance (Z-score > 2) GR00366-A-125 10.66 IL10
12 Increased shRNA abundance (Z-score > 2) GR00366-A-128 10.66 IL10
13 Increased shRNA abundance (Z-score > 2) GR00366-A-132 10.66 IL10
14 Increased shRNA abundance (Z-score > 2) GR00366-A-140 10.66 KIR2DS1 KIR3DL3 TGFB1
15 Increased shRNA abundance (Z-score > 2) GR00366-A-143 10.66 TGFB1
16 Increased shRNA abundance (Z-score > 2) GR00366-A-149 10.66 KIR3DL3
17 Increased shRNA abundance (Z-score > 2) GR00366-A-152 10.66 KIR3DL3 IL10
18 Increased shRNA abundance (Z-score > 2) GR00366-A-156 10.66 KIR3DL3
19 Increased shRNA abundance (Z-score > 2) GR00366-A-161 10.66 IL10
20 Increased shRNA abundance (Z-score > 2) GR00366-A-164 10.66 KIR2DS1
21 Increased shRNA abundance (Z-score > 2) GR00366-A-168 10.66 KIR3DL3 IL1B
22 Increased shRNA abundance (Z-score > 2) GR00366-A-169 10.66 TGFB1
23 Increased shRNA abundance (Z-score > 2) GR00366-A-170 10.66 IL1B
24 Increased shRNA abundance (Z-score > 2) GR00366-A-172 10.66 KIR2DS1
25 Increased shRNA abundance (Z-score > 2) GR00366-A-178 10.66 TGFB1
26 Increased shRNA abundance (Z-score > 2) GR00366-A-186 10.66 KIR3DL3
27 Increased shRNA abundance (Z-score > 2) GR00366-A-190 10.66 KIR3DL3
28 Increased shRNA abundance (Z-score > 2) GR00366-A-195 10.66 KIR2DS1
29 Increased shRNA abundance (Z-score > 2) GR00366-A-196 10.66 KIR2DS1 KIR3DL3
30 Increased shRNA abundance (Z-score > 2) GR00366-A-198 10.66 KIR2DS1 TGFB1 IL10 IL1B
31 Increased shRNA abundance (Z-score > 2) GR00366-A-199 10.66 KIR2DS1 KIR3DL3 IL1B
32 Increased shRNA abundance (Z-score > 2) GR00366-A-201 10.66 KIR3DL3
33 Increased shRNA abundance (Z-score > 2) GR00366-A-202 10.66 KIR2DS1 KIR3DL3
34 Increased shRNA abundance (Z-score > 2) GR00366-A-205 10.66 KIR3DL3
35 Increased shRNA abundance (Z-score > 2) GR00366-A-21 10.66 KIR2DS1
36 Increased shRNA abundance (Z-score > 2) GR00366-A-210 10.66 IL10
37 Increased shRNA abundance (Z-score > 2) GR00366-A-214 10.66 IL10
38 Increased shRNA abundance (Z-score > 2) GR00366-A-25 10.66 IL10
39 Increased shRNA abundance (Z-score > 2) GR00366-A-31 10.66 KIR3DL3
40 Increased shRNA abundance (Z-score > 2) GR00366-A-32 10.66 KIR2DS1
41 Increased shRNA abundance (Z-score > 2) GR00366-A-35 10.66 TGFB1
42 Increased shRNA abundance (Z-score > 2) GR00366-A-50 10.66 IL1B
43 Increased shRNA abundance (Z-score > 2) GR00366-A-51 10.66 IL1B
44 Increased shRNA abundance (Z-score > 2) GR00366-A-52 10.66 IL10
45 Increased shRNA abundance (Z-score > 2) GR00366-A-56 10.66 TGFB1
46 Increased shRNA abundance (Z-score > 2) GR00366-A-65 10.66 IL10
47 Increased shRNA abundance (Z-score > 2) GR00366-A-67 10.66 IL10
48 Increased shRNA abundance (Z-score > 2) GR00366-A-73 10.66 KIR2DS1 KIR3DL3
49 Increased shRNA abundance (Z-score > 2) GR00366-A-79 10.66 KIR3DL3 IL1B
50 Increased shRNA abundance (Z-score > 2) GR00366-A-80 10.66 IL10

MGI Mouse Phenotypes related to Autoimmune Gastritis:

47 (show all 14)
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.08 IFNG IL10 IL1B IL2 IL6 TGFB1
2 growth/size/body region MP:0005378 10.08 IFNG IL10 IL1B IL2 IL4 IL6
3 hematopoietic system MP:0005397 10.06 IFNG IL10 IL1B IL2 IL4 IL6
4 digestive/alimentary MP:0005381 10.05 IFNG IL10 IL2 IL4 IL6 TGFB1
5 endocrine/exocrine gland MP:0005379 10.04 IFNG IL10 IL2 IL4 IL6 TGFB1
6 immune system MP:0005387 10.03 IFNG IL10 IL1B IL2 IL4 IL6
7 craniofacial MP:0005382 10 IFNG IL10 IL1B IL4 TGFB1 TNF
8 integument MP:0010771 9.95 IFNG IL10 IL1B IL4 IL6 TGFB1
9 liver/biliary system MP:0005370 9.91 IFNG IL10 IL2 IL4 IL6 TGFB1
10 neoplasm MP:0002006 9.87 IFNG IL10 IL1B IL2 IL6 TGFB1
11 reproductive system MP:0005389 9.8 IFNG IL10 IL2 IL4 IL6 TGFB1
12 respiratory system MP:0005388 9.7 IFNG IL10 IL2 IL4 IL6 TGFB1
13 skeleton MP:0005390 9.5 IFNG IL10 IL1B IL4 IL6 TGFB1
14 vision/eye MP:0005391 9.17 IFNG IL10 IL2 IL4 IL6 TGFB1

Drugs & Therapeutics for Autoimmune Gastritis

Drugs for Autoimmune Gastritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Immunologic Factors
2 Antibodies, Antinuclear
3 Immunoglobulins
4 Antibodies

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Autoimmune Diseases And Serum Anti-Nuclear Antibodies Positivity In Non-Celiac Wheat Sensitivity Patients Completed NCT02248545

Search NIH Clinical Center for Autoimmune Gastritis

Genetic Tests for Autoimmune Gastritis

Anatomical Context for Autoimmune Gastritis

MalaCards organs/tissues related to Autoimmune Gastritis:

42
T Cells, Thyroid, Bone, Heart, Lung, Liver, Eye

The Foundational Model of Anatomy Ontology organs/tissues related to Autoimmune Gastritis:

20
The Stomach

Publications for Autoimmune Gastritis

Articles related to Autoimmune Gastritis:

(show top 50) (show all 169)
# Title Authors Year
1
Deficiency of micronutrients in patients affected by chronic atrophic autoimmune gastritis: A single-institution observational study. ( 30236765 )
2019
2
Insights into Pediatric Autoimmune Gastritis: Is There a Role for Helicobacter Pylori Infection? ( 30664567 )
2019
3
Subacute Combined Degeneration, Pernicious Anemia and Gastric Neuroendocrine Tumor Occured Simultaneously Caused by Autoimmune Gastritis. ( 30740042 )
2019
4
Prevalence of Autoimmune Gastritis in Individuals Undergoing Medical Checkups in Japan. ( 30918182 )
2019
5
Utility of a laboratory score in the prediction of gastric emptying in autoimmune gastritis patients. ( 28738729 )
2018
6
Utility of a laboratory score in the prediction of altered autonomic nervous system function in autoimmune gastritis. ( 29391305 )
2018
7
The Relations Among Serum Ghrelin, Motilin and Gastric Emptying and Autonomic Function in Autoimmune Gastritis. ( 29753372 )
2018
8
Autoimmune Gastritis in the Pediatric Age: An Underestimated Condition Report of Two Cases and Review. ( 29765934 )
2018
9
High incidence of autoimmune gastritis in patients misdiagnosed with two or more failures of H. pylori eradication. ( 29920721 )
2018
10
Iron deficiency workup reveals high incidence of autoimmune gastritis with parietal cell antibody as reliable screening test. ( 30502855 )
2018
11
Differences between older and young patients with autoimmune gastritis. ( 27444719 )
2017
12
Revisiting autoimmune gastritis in children and adolescents with type 1 diabetes. ( 28004477 )
2017
13
Upper gastrointestinal symptoms in autoimmune gastritis: A cross-sectional study. ( 28072728 )
2017
14
Micronutrient deficiencies in patients with chronic atrophic autoimmune gastritis: A review. ( 28216963 )
2017
15
Autoimmune gastritis: relationships with anemia and Helicobacter pylori status. ( 28276835 )
2017
16
Helicobacter pylori and necessary rationale for autoimmune gastritis. ( 28290721 )
2017
17
Hashimoto's Thyroiditis and Autoimmune Gastritis. ( 28491051 )
2017
18
Multiplex autoantibody detection for autoimmune liver diseases and autoimmune gastritis. ( 28522403 )
2017
19
Autoimmune gastritis: assessment of OLGA and OLGIM staging systems. ( 29492930 )
2017
20
Diminished salivary epidermal growth factor secretion: a link between Sjögren's syndrome and autoimmune gastritis? ( 26399281 )
2016
21
Assessment of Gastric Emptying in Patients with Autoimmune Gastritis. ( 26725066 )
2016
22
Oxyntic gastric atrophy in Helicobacter pylori gastritis is distinct from autoimmune gastritis. ( 26729016 )
2016
23
Induction of autoimmune gastritis by neonatal thymectomy requires autoantibodies and is prevented by anti-FcγR antibodies. ( 26748859 )
2016
24
Relationships between autonomic nerve function and gastric emptying in patients with autoimmune gastritis. ( 27059861 )
2016
25
Polyautoimmunity in autoimmune gastritis. ( 27085391 )
2016
26
Regulatory T Cells Control Th2-Dominant Murine Autoimmune Gastritis. ( 27259856 )
2016
27
Autoimmune gastritis. ( 27671008 )
2016
28
Malignant transformation of a gastric hyperplastic polyp in a context of Helicobacter pylori-negative autoimmune gastritis: a case report. ( 27729029 )
2016
29
Factors associated with elevated serum chromogranin A levels in patients with autoimmune gastritis. ( 27852542 )
2016
30
Mean platelet volume and red cell distribution width in autoimmune gastritis: confounding factors should be considered. ( 24433174 )
2015
31
Autoimmune gastritis in autoimmune thyroid disease. ( 25648057 )
2015
32
Single nucleotide polymorphisms related to vitamin B12 serum levels in autoimmune gastritis patients with or without pernicious anaemia. ( 25681243 )
2015
33
Autoimmune gastritis: Pathologist's viewpoint. ( 26576102 )
2015
34
Autoimmune gastritis among T1D individuals - important association? ( 27776198 )
2015
35
Are patients with autoimmune thyroid disease and autoimmune gastritis at risk of gastric neuroendocrine neoplasms type 1? ( 24118101 )
2014
36
The predictive value of mean platelet volume, plateletcrit and red cell distribution width in the differentiation of autoimmune gastritis patients with and without type I gastric carcinoid tumors. ( 24175991 )
2014
37
Diagnosis and classification of autoimmune gastritis. ( 24424193 )
2014
38
Dominant trait linked to chromosome 1 in DBA/2 mice for the resistance to autoimmune gastritis appears in bone marrow cells. ( 24770641 )
2014
39
Autoimmune gastritis presenting as iron deficiency anemia in childhood. ( 25400463 )
2014
40
A case of rheumatic valvular heart disease and autoimmune gastritis. ( 25535234 )
2014
41
Hepatitis C virus antibody positivity may not be associated with hepatitis C infection in patients with autoimmune gastritis. ( 23011039 )
2013
42
Autoimmune gastritis: novel clues to histological diagnosis. ( 23277173 )
2013
43
Autoimmune gastritis mediated by CD4+ T cells promotes the development of gastric cancer. ( 23378345 )
2013
44
Interleukin-21 and tumor necrosis factor-α are critical for the development of autoimmune gastritis in mice. ( 23425147 )
2013
45
Increased susceptibility to autoimmune gastritis in thymic stromal lymphopoietin receptor-deficient mice. ( 22124119 )
2012
46
Autoimmune gastritis: histology phenotype and OLGA staging. ( 22519568 )
2012
47
Successful endoscopic submucosal dissection of gastric carcinoid in a patient with autoimmune gastritis and systemic lupus erythematosus. ( 22687792 )
2012
48
Clinical profiles, endoscopic and laboratory features and associated factors in patients with autoimmune gastritis. ( 22710370 )
2012
49
Both IFN-γ and IL-17 are required for the development of severe autoimmune gastritis. ( 22777705 )
2012
50
Features of the atrophic corpus mucosa in three cases of autoimmune gastritis revealed by magnifying endoscopy. ( 22811721 )
2012

Variations for Autoimmune Gastritis

Expression for Autoimmune Gastritis

Search GEO for disease gene expression data for Autoimmune Gastritis.

Pathways for Autoimmune Gastritis

Pathways related to Autoimmune Gastritis according to GeneCards Suite gene sharing:

(show top 50) (show all 90)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.99 IFNG IL10 IL1B IL2 IL4 IL6
2
Show member pathways
13.78 IL10 IL1B IL2 IL4 IL6 TGFB1
3
Show member pathways
13.67 IFNG IL10 IL1B IL2 IL4 IL6
4
Show member pathways
13.54 IFNG IL10 IL1B IL2 IL4 IL6
5
Show member pathways
13.42 IL10 IL1B IL2 IL4 IL6 TGFB1
6
Show member pathways
13.39 IFNG IL10 IL1B IL2 IL4 IL6
7
Show member pathways
13.32 IL10 IL1B IL2 IL4 IL6 TGFB1
8
Show member pathways
13.15 IFNG IL1B IL2 IL4 TNF
9
Show member pathways
13.15 IFNG IL10 IL1B IL2 IL6 TGFB1
10 12.86 IFNG IL2 IL4 IL6 TGFB1
11
Show member pathways
12.75 IL1B IL2 IL6 TGFB1 TNF
12
Show member pathways
12.74 IL2 IL4 IL6 TNF
13
Show member pathways
12.72 IFNG IL1B IL6 TNF
14
Show member pathways
12.68 IFNG IL10 IL2 IL4 TNF
15
Show member pathways
12.67 IFNG IL10 IL1B IL2 IL6 TNF
16 12.65 IFNG IL10 IL1B IL2 IL4 TNF
17
Show member pathways
12.64 IFNG IL10 IL1B IL2 IL4 IL6
18
Show member pathways
12.62 IFNG IL10 IL1B IL2 IL4 IL6
19
Show member pathways
12.59 IFNG IL2 IL4 KIR2DS1 KIR2DS4 TNF
20
Show member pathways
12.47 IFNG IL10 IL2 IL4 IL6
21
Show member pathways
12.46 IFNG IL10 IL1B IL2 IL4 IL6
22
Show member pathways
12.43 IFNG IL1B IL2 IL4 IL6 TNF
23
Show member pathways
12.42 IFNG IL1B IL4 IL6 TNF
24 12.39 IL2 IL6 TGFB1 TNF
25
Show member pathways
12.37 IFNG IL10 IL1B IL4 TGFB1 TNF
26
Show member pathways
12.34 IFNG IL1B IL6 TNF
27 12.33 IFNG IL10 IL1B IL6 TGFB1 TNF
28
Show member pathways
12.32 IL10 IL1B IL2 IL6 TNF
29
Show member pathways
12.29 IFNG IL1B IL4 IL6 TNF
30
Show member pathways
12.27 IFNG IL10 IL1B IL2 IL4 IL6
31 12.25 IFNG IL6 TGFB1 TNF
32 12.24 IL10 IL1B IL6 TNF
33
Show member pathways
12.19 IL1B IL6 TNF
34
Show member pathways
12.19 IL6 TGFB1 TNF
35
Show member pathways
12.18 IFNG IL1B TNF
36
Show member pathways
12.15 IFNG IL1B IL4 IL6 TNF
37
Show member pathways
12.14 IFNG IL10 IL1B IL2 IL4 IL6
38 12.12 IFNG IL1B TGFB1 TNF
39 12.1 IFNG IL10 IL2 IL4 IL6 TNF
40
Show member pathways
12.09 IFNG IL10 IL1B IL2 IL6 TGFB1
41 12.08 IL10 IL1B IL4 IL6 TGFB1 TNF
42 12.07 IFNG IL1B TNF
43
Show member pathways
12.07 IL10 IL6 TGFB1
44
Show member pathways
12.07 IFNG IL1B IL2 IL4
45 12.05 IL6 TGFB1 TNF
46 12.03 IFNG IL1B IL6 TGFB1
47 12 IL1B IL6 TGFB1 TNF
48 11.99 IL1B IL4 IL6 TNF
49 11.99 IFNG IL1B IL2 IL4 IL6 TGFB1
50 11.98 IFNG IL1B IL6 TGFB1 TNF

GO Terms for Autoimmune Gastritis

Cellular components related to Autoimmune Gastritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.56 IFNG IL10 IL1B IL2 IL4 IL6
2 extracellular space GO:0005615 9.23 IFNG IL10 IL1B IL2 IL4 IL6

Biological processes related to Autoimmune Gastritis according to GeneCards Suite gene sharing:

(show top 50) (show all 68)
# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.99 IL10 IL1B IL6 TGFB1 TNF
2 MAPK cascade GO:0000165 9.97 IL1B IL2 TGFB1 TNF
3 cellular response to lipopolysaccharide GO:0071222 9.93 IL10 IL1B IL6 TNF
4 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.91 IL1B IL6 TGFB1 TNF
5 response to organic substance GO:0010033 9.89 IL10 TGFB1 TNF
6 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.88 IL6 TGFB1 TNF
7 positive regulation of gene expression GO:0010628 9.88 IFNG IL1B IL4 IL6 TGFB1 TNF
8 cellular response to organic cyclic compound GO:0071407 9.87 IL1B TGFB1 TNF
9 positive regulation of DNA-binding transcription factor activity GO:0051091 9.87 IL10 IL1B IL6 TNF
10 regulation of insulin secretion GO:0050796 9.86 IFNG IL1B TNF
11 positive regulation of interleukin-6 production GO:0032755 9.86 IL1B IL6 TNF
12 humoral immune response GO:0006959 9.85 IFNG IL6 TNF
13 negative regulation of fat cell differentiation GO:0045599 9.83 IL6 TGFB1 TNF
14 extrinsic apoptotic signaling pathway GO:0097191 9.83 IFNG TGFB1 TNF
15 positive regulation of interferon-gamma production GO:0032729 9.82 IL1B IL2 TNF
16 positive regulation of nitric oxide biosynthetic process GO:0045429 9.82 IFNG IL1B TNF
17 protein kinase B signaling GO:0043491 9.8 IL1B TGFB1 TNF
18 lipopolysaccharide-mediated signaling pathway GO:0031663 9.79 IL1B TGFB1 TNF
19 negative regulation of mitotic cell cycle GO:0045930 9.79 IL10 TGFB1 TNF
20 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.78 IFNG IL2 IL4 IL6
21 positive regulation of protein phosphorylation GO:0001934 9.77 IFNG IL1B IL2 TGFB1 TNF
22 negative regulation of neurogenesis GO:0050768 9.76 IL1B IL6 TNF
23 positive regulation of protein complex assembly GO:0031334 9.75 IFNG TGFB1 TNF
24 negative regulation of myoblast differentiation GO:0045662 9.74 TGFB1 TNF
25 positive regulation of osteoclast differentiation GO:0045672 9.74 IFNG TNF
26 positive regulation of chemokine production GO:0032722 9.74 IL6 TNF
27 positive regulation of T cell differentiation GO:0045582 9.73 IL2 IL4
28 positive regulation of histone acetylation GO:0035066 9.73 IL1B TGFB1
29 myeloid dendritic cell differentiation GO:0043011 9.73 IL4 TGFB1
30 negative regulation of lipid catabolic process GO:0050995 9.73 IL1B TNF
31 positive regulation of T cell proliferation GO:0042102 9.73 IL1B IL2 IL4 IL6
32 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.72 IL1B TNF
33 negative regulation of growth of symbiont in host GO:0044130 9.72 IL10 TNF
34 positive regulation of interleukin-17 production GO:0032740 9.72 IL2 TGFB1
35 negative regulation of interleukin-17 production GO:0032700 9.72 IFNG TGFB1
36 positive regulation of immunoglobulin secretion GO:0051024 9.72 IL2 IL6
37 positive regulation of regulatory T cell differentiation GO:0045591 9.71 IL2 TGFB1
38 positive regulation of isotype switching to IgG isotypes GO:0048304 9.71 IL2 IL4
39 negative regulation of lipid storage GO:0010888 9.71 IL6 TNF
40 positive regulation of glial cell proliferation GO:0060252 9.71 IL1B IL6 TNF
41 endothelial cell apoptotic process GO:0072577 9.7 IL10 TNF
42 positive regulation of chemokine biosynthetic process GO:0045080 9.7 IL1B TNF
43 positive regulation of MHC class II biosynthetic process GO:0045348 9.7 IL10 IL4
44 regulation of establishment of endothelial barrier GO:1903140 9.7 IL1B TNF
45 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.7 IFNG IL1B TNF
46 cytokine-mediated signaling pathway GO:0019221 9.7 IL10 IL1B IL2 IL4 IL6 TGFB1
47 negative regulation of cytokine secretion involved in immune response GO:0002740 9.69 IL10 TNF
48 regulation of regulatory T cell differentiation GO:0045589 9.69 IFNG IL2 TGFB1
49 positive regulation of fever generation GO:0031622 9.68 IL1B TNF
50 regulation of isotype switching GO:0045191 9.67 IL10 IL4

Molecular functions related to Autoimmune Gastritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.35 IL10 IL2 IL4 IL6 TGFB1
2 cytokine activity GO:0005125 9.23 IFNG IL10 IL1B IL2 IL4 IL6

Sources for Autoimmune Gastritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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