Autoimmune Pancreatitis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: ATM024 MIFTS: 50	Autoimmune Pancreatitis Categories: Bone diseases, Endocrine diseases, Gastrointestinal diseases, Genetic diseases, Immune diseases, Rare diseases
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Aliases & Classifications for Autoimmune Pancreatitis

MalaCards integrated aliases for Autoimmune Pancreatitis:

Name: Autoimmune Pancreatitis ¹² ⁵⁴ ⁶⁰ ¹⁵ ⁷⁴

Lymphoplasmocytic Sclerosing Pancreatitis ⁵⁴

Aip ⁶⁰

Characteristics:

Orphanet epidemiological data:

⁶⁰

autoimmune pancreatitis
Inheritance: Not applicable;

Classifications:

MalaCards categories:
Global: Rare diseases Genetic diseases
Anatomical: Gastrointestinal diseases Bone diseases Immune diseases Endocrine diseases

See all MalaCards categories (disease lists)

ICD10: ³⁵

Diseases of the digestive system

Disorders of gallbladder, biliary tract and pancreas

Other diseases of pancreas

Other chronic pancreatitis

Orphanet: ⁶⁰

Rare gastroenterological diseases

Rare systemic and rhumatological diseases

External Ids:

Disease Ontology ¹² DOID:0040091

ICD10 via Orphanet ³⁵ K86.1

UMLS via Orphanet ⁷⁵ C2609129

Orphanet ⁶⁰ ORPHA103919

UMLS ⁷⁴ C2609129

Sources

Summaries for Autoimmune Pancreatitis

NIH Rare Diseases : ⁵⁴ Autoimmune pancreatitis affects the pancreas, a gland behind the stomach and in front of the spine, and can also affect the bile ducts, salivary glands, kidneys, and lymph nodes. It is thought to occur when the immune system mistakenly begins to attack these healthy body tissues, glands, and organs. Common signs and symptoms include painless jaundice, weight loss, and noncancerous masses in the pancreas and other organs. Treatment often involves corticosteroids. The condition may recur following treatment, and require additional therapy.

MalaCards based summary : Autoimmune Pancreatitis, also known as lymphoplasmocytic sclerosing pancreatitis, is related to pancreas adenocarcinoma and colitis. An important gene associated with Autoimmune Pancreatitis is CA2 (Carbonic Anhydrase 2), and among its related pathways/superpathways are NF-kappaB Signaling and Allograft rejection. The drugs rituximab and Antineoplastic Agents, Immunological have been mentioned in the context of this disorder. Affiliated tissues include the pancreas, pancreas and pituitary, and related phenotypes are digestive/alimentary and craniofacial

Disease Ontology : ¹² An autoimmune disease of endocrine system that is located in the pancreas.

Wikipedia : ⁷⁷ Autoimmune pancreatitis is an increasingly recognized type of chronic pancreatitis that can be... more...

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Related Diseases for Autoimmune Pancreatitis

Diseases in the Pancreatitis family:

Pancreatitis, Hereditary	Autoimmune Pancreatitis
Acute Pancreatitis	Prss1-Related Hereditary Pancreatitis
Autoimmune Pancreatitis Type 2	Autoimmune Pancreatitis Type 1
Recurrent Acute Pancreatitis

Diseases related to Autoimmune Pancreatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 219)

#	Related Disease	Score	Top Affiliating Genes
1	pancreas adenocarcinoma	30.1	FOXP3 HRAS PRSS1
2	colitis	29.9	CTLA4 FOXP3 IL10
3	autoimmune lymphoproliferative syndrome	29.3	CTLA4 HRAS IL10
4	alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity	29.0	CTLA4 FOXP3 IL10 TNFSF13B
5	autoimmune disease	28.9	CTLA4 ENO1 FCRL3 FOXP3 IL10 TNFSF13B
6	systemic lupus erythematosus	28.9	CTLA4 FCRL3 FOXP3 IL10 TNFSF13B
7	rheumatoid arthritis	28.7	CTLA4 FCRL3 FOXP3 IL10 TNFSF13B
8	autoimmune pancreatitis type 1	12.3
9	porphyria, acute intermittent	12.3
10	autoimmune pancreatitis type 2	12.3
11	aip-related familial isolated pituitary adenomas	12.2
12	acromegaly	12.1
13	pituitary adenoma 1, multiple types	12.1
14	acute interstitial pneumonia	12.0
15	pituitary adenoma, prolactin-secreting	12.0
16	pituitary adenoma	11.7
17	familial isolated pituitary adenoma	11.7
18	igg4-related disease	11.6
19	gigantism	11.6
20	pituitary tumors	11.5
21	pituitary apoplexy	11.5
22	acroleukopathy, symmetric	11.5
23	mikulicz disease	11.4
24	hepatitis b	11.3
25	chester porphyria	11.2
26	pancreatitis	11.2
27	carney complex variant	11.1
28	multiple endocrine neoplasia, type iv	11.1
29	cell type benign neoplasm	11.1
30	endocrine organ benign neoplasm	11.1
31	pituitary infarct	11.1
32	hyperpituitarism	11.1
33	pituitary gland disease	11.1
34	functioning pituitary adenoma	11.1
35	hormone producing pituitary cancer	11.1
36	growth hormone secreting pituitary adenoma	11.1
37	cancer-associated retinopathy	11.1
38	acth-secreting pituitary adenoma	11.1
39	pituitary adenoma 4, acth-secreting	11.0
40	silent pituitary adenoma	11.0
41	null pituitary adenoma	11.0
42	pancreatic cancer	10.6
43	cholangitis	10.6
44	sclerosing cholangitis	10.5
45	porphyria	10.4
46	adenocarcinoma	10.4
47	recurrent acute pancreatitis	10.3	CFTR PRSS1
48	autoimmune retinopathy	10.3	CA2 ENO1
49	neuroretinitis	10.3	CA2 CTLA4
50	johanson-blizzard syndrome	10.3	CFTR UBR2

Graphical network of the top 20 diseases related to Autoimmune Pancreatitis:

Sources

Symptoms & Phenotypes for Autoimmune Pancreatitis

MGI Mouse Phenotypes related to Autoimmune Pancreatitis:

⁴⁷

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	digestive/alimentary	MP:0005381	9.73	CA2 CFTR CTLA4 FOXP3 HRAS IL10
2	craniofacial	MP:0005382	9.72	CFTR FOXP3 HRAS IL10 SPTAN1
3	endocrine/exocrine gland	MP:0005379	9.7	CA2 CFTR CTLA4 FOXP3 HRAS IL10
4	normal	MP:0002873	9.5	CFTR CTLA4 FOXP3 HRAS IL10 KCNA3
5	respiratory system	MP:0005388	9.1	CA2 CFTR CTLA4 FOXP3 HRAS IL10

Sources

Drugs & Therapeutics for Autoimmune Pancreatitis

Drugs for Autoimmune Pancreatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 27)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

rituximab

Approved

Phase 1, Phase 2

174722-31-7

10201696

Antineoplastic Agents, Immunological

Phase 1, Phase 2

Antirheumatic Agents

Phase 1, Phase 2

Immunologic Factors

Phase 1, Phase 2

Immunoglobulin G

Phase 1, Phase 2,Not Applicable

Immunoglobulins

Phase 1, Phase 2,Not Applicable

Antibodies

Phase 1, Phase 2,Not Applicable

Lenalidomide

Approved

Phase 1

191732-72-6

216326

Synonyms:

191732-72-6

1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline

1-oxo-2-(2,6-Dioxopiperidin-3-yl)-4-aminoisoindoline

3-(4-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione

3-(4-amino-1-Oxoisoindolin-2-yl)piperidine-2,6-dione

3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione

3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione

3-(7-Amino-3-oxo-1H-isoindol-2-yl)-piperidine-2,6-dione

346670-73-3

443912-14-9

AC1L50II

AC-914

AKOS005146276

ALBB-015321

Bio-0168

C467567

CC 5013

CC5013

CC-5013

CC-5013, Revlimid, Lenalidomide

CDC 501

CDC-501

CDC-5013

Celgene brand of lenalidomide

Celgene brand OF lenalidomide

CHEMBL848

CID216326

D04687

DB00480

EC-000.2340

ENMD-0997

I06-0831

IMID-1

IMiD3

IMiD3 cpd

IMiD3 CPD

IMID-5013

Lenalidomida

lenalidomide

Lenalidomide

Lenalidomide (USAN/INN)

Lenalidomide [USAN]

LS-184040

MolPort-003-848-370

NCGC00167491-01

NSC747972

Revamid

Revimid

Revlimid

Revlimid (Celgene)

Revlimid (TN)

S1029_Selleck

STK639603

Thalidomide analog CC-5013

UNII-F0P408N6V4

Angiogenesis Inhibitors

Phase 1

Angiogenesis Modulating Agents

Phase 1

Pancrelipase

Approved, Investigational

53608-75-6

Prednisone

Approved, Vet_approved

Not Applicable

53-03-2

5865

Synonyms:

(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione

(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione

(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione

.delta. E

.delta.(sup1)-Cortisone

.delta.1-Cortisone

.delta.1-Dehydrocortisone

.delta.-Cortelan

.delta.-Cortisone

.delta.-Cortone

.delta.-E

.delta.sone

1,2-Dehydrocortisone

1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione

1,4-Pregnadiene-17a,21-diol-3,11,20-trione

1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione

1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione

1,4-Pregnadiene-17α,21-diol-3,11,20-trione

17,21-Dihydroxypregna-1,4-diene-3,11,20-trione

17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione

1-Cortisone

1-Dehydrocortisone

53-03-2

68-59-7

81552_FLUKA

AC-11112

AC1L1LB2

AC1Q29EZ

Acis brand OF prednisone

ACon0_000082

ACon1_000297

Adasone

AI3-52939

Ancortone

apo-Prednisone

Apo-prednisone

Apo-Prednisone

Apotex brand OF prednisone

Aventis brand OF prednisone

Betapar

Bicortone

Bio-0649

BPBio1_000323

BRD-K85883481-001-04-2

BSPBio_000293

C07370

C21H26O5

Cartancyl

CCRIS 2646

CHEBI:8382

CHEMBL635

CID5865

Colisone

Cortan

Cortancyl

Cortidelt

Cotone

CPD001227202

Cutason

Dacorten

Dacortin

DB00635

Decortancyl

Decortin

Decortisyl

Dehydrocortisone

Dekortin

Delcortin

Dellacort

Dellacort A

delta cortelan

Delta Cortelan

Delta E

Delta E.

delta(sup 1)-Cortisone

delta(sup 1)-Dehydrocortisone

delta-1-Cortisone

delta-1-Dehydrocortisone

Delta-cortelan

Delta-Cortelan

Deltacortene

delta-Cortisone

Deltacortisone

Delta-cortisone

delta-Cortone

Deltacortone

Delta-cortone

Delta-dome

Delta-Dome

Deltasone

Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone

Deltison

Deltisona

Deltisone

Deltra

Diadreson

Di-Adreson

Diba brand OF prednisone

Econosone

EINECS 200-160-3

Encorton

Encortone

Enkortolon

Enkorton

Fawns and mcallan brand OF prednisone

Fernisone

Ferring brand OF prednisone

Fiasone

GALENpharma brand OF prednisone

Halsey drug brand OF prednisone

Hexal brand OF prednisone

HMS1568O15

HMS2090J13

Hoechst brand OF prednisone

Hostacortin

HSDB 3168

ICN brand OF prednisone

Incocortyl

In-Sone

Juvason

Kortancyl

Lichtenstein brand OF prednisone

Liquid pred

Liquid Pred

Lisacort

LMST02030180

Lodotra

LS-1325

MEGxm0_000443

Me-Korti

Merck brand OF prednisone

Merz brand OF prednisone

Metacortandracin

Meticorten

Meticorten (Veterinary)

Metrevet (Veterinary)

Mibe brand OF prednisone

MLS001061265

MLS001304073

MLS001335907

MLS001335908

MLS002154191

MLS002207083

MolPort-001-740-041

NCGC00090766-01

NCGC00090766-02

NCGC00090766-03

NCI60_000008

NCI-C04897

Nisona

Nizon

Novoprednisone

NSC 10023

NSC10023

Nurison

Orasone

Origen Prednisone

P1276

P6254_SIGMA

Panafcort

Panasol

Paracort

Parmenison

Pehacort

Pharmacia brand OF prednisone

PRD

Precort

Predeltin

Predni tablinen

Prednicen-M

Prednicorm

Prednicort

Prednicot

Prednidib

Prednilonga

Predniment

Prednison

Prednison acsis

Prednison galen

Prednison hexal

Prednisona

Prednisona [INN-Spanish]

Prednisone

Prednisone [INN:BAN]

Prednisone Intensol

Prednisonum

Prednisonum [INN-Latin]

Prednitone

Prednizon

Prednovister

Presone

Prestwick_405

Prestwick0_000077

Prestwick1_000077

Prestwick2_000077

Prestwick3_000077

Pronison

Pronisone

Rectodelt

Retrocortine

S1622_Selleck

SAM002264641

Schering-plough brand OF prednisone

Seatrace brand OF prednisone

Servisone

SK-Prednisone

SMR000718760

SMR001227202

Solvay brand OF prednisone

Sone

SPBio_002214

Sterapred

Supercortil

Trommsdorff brand OF prednisone

U 6020

Ultracorten

Ultracortene

UNII-VB0R961HZT

Winpred

WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ

Wojtab

Zenadrid

Zenadrid (veterinary)

Zenadrid [veterinary]

ZINC03875357

Vitamin D

Approved, Nutraceutical, Vet_approved

1406-16-2

Calcium

Approved, Nutraceutical

7440-70-2

271

Synonyms:

Blood coagulation factor XIII

Ca(2+)

Ca2+

Calcio

Calcium

Calcium element

CALCIUM ion

Calcium, doubly charged positive ion

Calcium, elemental

Coagulation factor XIII

Elemental calcium

Factor XIII

Factor XIII a chain

Factor XIII a-chain

Factor XIII transamidase

Factor XIII, coagulation

Fibrin stabilizing factor

Fibrinase

Kalzium

Laki lorand factor

Laki-lorand factor

Stabilizing factor, fibrin

Transamidase, factor XIII

XIII, coagulation factor

Ergocalciferol

Approved, Nutraceutical

50-14-6

5280793

Synonyms:

(+)-Vitamin D2

(3b,5Z,7E,22E)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol

(3beta,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol

(3beta,5Z,7E,22E)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol

(3-beta,5Z,7E,22E)-9,10-Secoergosta-5,7,10,(19),22-tetraen-3-ol

(3S,5Z,7E,14xi,17alpha,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol

(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol

(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol

(3β,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol

(5E,7E,22E)-9,10-Secoergosta-5,7,10,22-tetraen-3-ol

(5Z,7E,22E)-(3S)-9,10-seco-5,7,10(19),22-ergostatetraen-3-ol

(5Z,7E,22E)-(3S)-9,10-seco-5,7,10(19),22-Ergostatetraen-3-ol

(5Z,7E,22E)-(3S)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol

(5Z,7E,22E)-(3S)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol

22-Tetraen 3beta 9,10,secoergosta-5,7,10(19)-ol

31316-19-5

47768_SUPELCO

4-Methylene-3-[2-[tetrahydro-7a-methyl-1-(1,4,5-trimethyl-2-hexenyl)-4(3ah)-indanylidene]ethylidene]-cyclohexanol

50-14-6

7489-18-1

7E677DC1-E1C4-4FC5-8F4A-BCE1857F7E87

8017-28-5

9,10,Secoergosta-5,7,10(19),22-tetraen 3.beta.-ol

9,10-Seco(5Z,7E,22E)-5,7,10(19),22-ergostatetraen-3-ol

9,10-Secoergosta-5,7,10(19),22-tetraen-3-beta-ol

9,10-Secoergosta-5,7,10(19),22-tetraen-3b-ol

95220_FLUKA

95220_SIGMA

AC-1355

AC1L1FIE

AC1NQXLH

AC1NS4DE

AC1NS9GI

AC1NSSVD

AC1NWAM3

AC1O5EDK

AC1O6WAM

ACon1_002187

Activated ergosterol

beta-Ol

bmse000510

BPBio1_000418

BSPBio_000380

BSPBio_001974

buco-D

Buco-D

C05441

C28H44O

Calciferol

Calciferol (TN)

Calciferol (vitamin D2)

CALCIFEROL IN A GELATIN MATRIX

CALCIFEROL, U.S.P.

Calciferols

Calciferolum

Calciferon 2

CHEBI:28934

CHEMBL1536

CID11003810

CID3249

CID5280793

CID5315257

CID5353610

CID5356615

CID5702050

CID6432478

CID6536972

component of Geltabs Vitamin D

Condacaps

Condocaps

Condol

Crtron

Crystallina

D00187

D2, Vitamin

Daral

D-Arthin

Davitamon D

Davitin

DB00153

Decaps

Dee-osterol

Dee-Osterol

Dee-ron

Dee-Ron

Dee-ronal

Dee-Ronal

Dee-roual

Dee-Roual

delta-Arthin

Deltalin

delta-Tracetten

De-rat concentrate

Deratol

Detalup

Diactol

Divit urto

Doral

Drisdol

Drisdol (TN)

D-Tracetten

E5750_SIGMA

EINECS 200-014-9

Ercalciol

ergocalciferol

Ergocalciferol

Ergocalciférol

Ergocalciferol (D2)

Ergocalciferol (JP15/USP)

Ergocalciferol [INN:BAN:JAN]

Ergocalciferol oil

Ergocalciferol: Vitamin D

Ergocalciferolo

Ergocalciferolo [DCIT]

Ergocalciferols

Ergocalciferolum

Ergocalciferolum [INN-Latin]

Ergorone

Ergosterol activated

Ergosterol irradiated

'Ergosterol irradiated'

Ergosterol, irradiated

Ertron

Fortodyl

Geltabs

Geltabs Vitamin D

Haliver

Hi-deratol

Hi-Deratol

HMS1920K20

HMS2091B19

HMS502I07

HSDB 819

Hyperkil

I05-0022

IDI1_000805

Infron

Irradiated ergosta-5,7,22-trien-3.beta.-ol

Irradiated ergosta-5,7,22-trien-3beta-ol

Irradiated ergosta-5,7,22-trien-3-beta-ol

Irradiated ergosterol

LMST03010001

LMST03010014

LS-3228

MEGxm0_000466

Metadee

Mina D2

MLS001332467

MLS001332468

MolPort-001-740-057

MolPort-001-793-930

MolPort-002-526-645

MolPort-003-666-178

MolPort-006-822-629

Mulsiferol

Mykostin

NCGC00142497-01

NCGC00179579-01

NCGC00179579-02

Novovitamin-D

NSC 62792

NSC62792

Oleovitamin D

Oleovitamin D, Synthetic

Oleovitamin D2

Osteil

Ostelin

Prestwick_554

Prestwick3_000420

Radiostol

Radstein

Radsterin

Rodine C

Rodinec

Shock-ferol

Shock-ferol sterogyl

SMR000857106

Sorex C.R

Sorex C.R.

SPECTRUM1500276

Spectrum5_000666

ST057150

Sterogyl

STOCK1N-53397

Synthetic vitamin D

Synthetic Vitamin D

UNII-VS041H42XC

Uvesterol D

Uvesterol-D

Vigantol

vio D

vio-D

Vio-D

Viostdrol

Viosterol

Viosterol in oil

Viosterol in Oil

Vitamin D 2

vitamin d-2

Vitamin D2

Vitamin- D2

VITAMIN D2

VITAMIN D2 WATER DISPERSABLE U.S.P.

Vitamin-?D2

VITAMIN_D2

Vitamina D2

Vitavel-D

WLN: L56 FYTJ A1 BY1&1U1Y1&Y1&1 FU2U- BL6YYTJ AU1 DQ

ZINC04474571

ZINC04629876

Liver Extracts

pancreatin

Calciferol

Vitamins

Vitamin D2

Bone Density Conservation Agents

Hormones

Calcium, Dietary

Micronutrients

Trace Elements

Nutrients

Ergocalciferols

Interventional clinical trials:

(show all 14)

#	Name	Status	NCT ID	Phase	Drugs
1	Rituximab in IgG4-RD: A Phase 1-2 Trial	Completed	NCT01584388	Phase 1, Phase 2	Rituximab
2	Evaluation of a New EUS Guided Biopsy Needle (SharkCore) Comparing to Standard EUS Needle (ProCore)	Withdrawn	NCT02766842	Phase 2
3	Treatment of IgG4-Related Disease With Revlimid and Rituximab	Active, not recruiting	NCT02705638	Phase 1	Rituximab;Lenalidomide
4	EUS-guided Procore-biopsy in Diagnosing Autoimmune Pancreatitis	Unknown status	NCT01774513	Not Applicable
5	Follow-up Study of Complications of Acute Pancreatitis	Unknown status	NCT02305914
6	Pancreatic Duct Evaluation in Autoimmune Pancreatitis: MR Pancreatography	Completed	NCT01773031
7	Evaluation of EUS-guided FNA for Diagnosing Autoimmune Pancreatitis	Completed	NCT03241797	Not Applicable
8	Genetic Analysis for Predicting of Relapse During Steroid Treatment for Autoimmune Pancreatitis (AIP)	Completed	NCT00444444
9	CT Pancreas Perfusion	Completed	NCT00588367
10	A Randomized Prospective Comparison of the New EUS Guided Acquire TM Needle Biopsy vs EUS Guided Fine Needle Aspiration for Suspected Solid Gastrointestinal Lesions	Completed	NCT03109639	Not Applicable
11	Diagnostic Yield of FNA Needle and FNB Needle for Autoimmune Pancreatitis	Recruiting	NCT03753815	Not Applicable
12	Treatment of Obstructive Jaundice in Autoimmune Pancreatitis and/or Immunoglobulin G4-related Sclerosing Cholangitis by Corticosteroids	Active, not recruiting	NCT02797665	Not Applicable	corticosteroids
13	Assessment of the Different Etiological and Susceptibility Markers in Patients With Pancreatitis: Investigating IG4, Cytomegalovirus, Coxsackie- Virus, Genetic Polymorphism of Vitamin D Receptor Gene	Not yet recruiting	NCT03830073
14	Efficacy of Secretin MRCP in the Diagnosis and Follow up of Auto Immune Pancreatitis	Withdrawn	NCT01845467

Search NIH Clinical Center for Autoimmune Pancreatitis

Sources

Genetic Tests for Autoimmune Pancreatitis

Sources

Anatomical Context for Autoimmune Pancreatitis

The Foundational Model of Anatomy Ontology organs/tissues related to Autoimmune Pancreatitis:

²⁰

The Pancreas

MalaCards organs/tissues related to Autoimmune Pancreatitis:

⁴²

Pancreas, Pituitary, Kidney, Salivary Gland, Lymph Node, T Cells, Bone

Sources

Publications for Autoimmune Pancreatitis

Articles related to Autoimmune Pancreatitis:

(show top 50) (show all 1182)

#	Title	Authors	Year
1	Type 2 Autoimmune Pancreatitis (Idiopathic Duct-Centric Pancreatitis) Highlighting Patients Presenting as Clinical Acute Pancreatitis: A Single-Center Experience. ( 30970429 )	Oh D...Kim MH	2019
2	Differentiating focal autoimmune pancreatitis and pancreatic ductal adenocarcinoma: contrast-enhanced MRI with special emphasis on the arterial phase. ( 31028441 )	Kwon JH...Lee SS	2019
3	High accuracy differentiating autoimmune pancreatitis from pancreatic ductal adenocarcinoma by immunoglobulin G glycosylation. ( 30622446 )	Shih HC...Chang YT	2019
4	Risk Factors for Rate of Relapse and Effects of Steroid Maintenance Therapy in Patients With Autoimmune Pancreatitis: Systematic Review and Meta-analysis. ( 30312787 )	Tacelli M...Camm? C	2019
5	Coexisting Mucinous Cystic Neoplasm of the Pancreas and Type 1 Autoimmune Pancreatitis. ( 30424589 )	Kim MJ...Hong SM	2019
6	Autoimmune pancreatitis in children: A single centre experience in diagnosis, management and long term follow up. ( 30455055 )	Lee HM...Grammatikopoulos T	2019
7	IgG4 related autoimmune pancreatitis and sclerosing cholangitis. ( 30457561 )	Ufuk F...Duran M	2019
8	Risk Factors for Pancreatic Stone Formation in Type 1 Autoimmune Pancreatitis: A Long-term Japanese Multicenter Analysis of 624 Patients. ( 30540679 )	Ito T...Chiba T	2019
9	IgG4-related hypophysitis in patients with autoimmune pancreatitis. ( 30607745 )	Kanie K...Takahashi Y	2019
10	A Diagnostically Challenging Case of Autoimmune Pancreatitis Due to Contamination of the Pathological Specimen with Early Gastric Cancer. ( 30626846 )	Morino M...Mashima H	2019
11	Pancreatic Cystic Lesions in Cases of Autoimmune Pancreatitis. ( 30640232 )	Matsubayashi H...Kubota K	2019
12	Relapse patterns and predictors of IgG4-related diseases involved with autoimmune pancreatitis: A single-center retrospective study of 115 patients. ( 30701685 )	Miki M...Ogawa Y	2019
13	Native T1 mapping of autoimmune pancreatitis as a quantitative outcome surrogate. ( 30707275 )	Zhu L...Jin Z	2019
14	Recent Updates on the Relationship between Cancer and Autoimmune Pancreatitis. ( 30713326 )	Okamoto A...Kudo M	2019
15	Autoimmune Pancreatitis Exhibiting Pancreatic Duct Wall Thickening. ( 30713329 )	Azuma S...Yazumi S	2019
16	A case of high-grade pancreatic intraepithelial neoplasia concomitant with type 1 autoimmune pancreatitis: the process underlying both conditions. ( 30719801 )	Sugiyama T...Nakamura N	2019
17	Delayed pancreatic ductal leakage after EUS-FNA for autoimmune pancreatitis. ( 30719995 )	Ikarashi S...Terai S	2019
18	Unclassified autoimmune pancreatitis mimicking pancreatic cancer. ( 30740201 )	Marinho R...Nunes V	2019
19	A Nondilated Main Pancreatic Duct Predicts Type 2 Autoimmune Pancreatitis: Comparative Study of Resected Pancreatic Head Masses. ( 30759428 )	Pel?ez-Luna M...Angeles A	2019
20	Case of IgG4-associated sclerosing cholangitis with normal serum IgG4 concentration, diagnosed by anti-laminin 511-E8 antibody: a novel autoantibody in patients with autoimmune pancreatitis. ( 30760486 )	Kato Y...Chiba T	2019
21	Kidney Involvement in Patients with Type 1 Autoimmune Pancreatitis. ( 30781677 )	Vujasinovic M...L?hr JM	2019
22	Differentiation of Autoimmune Pancreatitis from Pancreatic Cancer Remains Challenging. ( 30815742 )	Dickerson LD...Yip VS	2019
23	Clinical characteristics of autoimmune pancreatitis with IgG4 related kidney disease. ( 30826634 )	Kuruma S...Tabata T	2019
24	Nivolumab-related pancreatitis with autoimmune pancreatitis-like imaging features. ( 30828866 )	Tanaka T...Kodama Y	2019
25	Combination Therapy with Empagliflozin and Insulin Results in Successful Glycemic Control: A Case Report of Uncontrolled Diabetes Caused by Autoimmune Pancreatitis and Subsequent Steroid Treatment. ( 30895163 )	Kishimoto M...Adachi M	2019
26	Impact of sclerosing dacryoadenitis/sialadenitis on relapse during steroid therapy in patients with type 1 autoimmune pancreatitis. ( 30915865 )	Ishii Y...Chayama K	2019
27	Feasibility and usefulness of endoscopic ultrasonography-guided shear-wave measurement for assessment of autoimmune pancreatitis activity: a prospective exploratory study. ( 30993580 )	Ohno E...Honda T	2019
28	Methotrexate as Induction of Remission Therapy for Type 1 Autoimmune Pancreatitis. ( 30998520 )	Rovati L...Della-Torre E	2019
29	Management of Autoimmune Pancreatitis. ( 31042584 )	Akshintala VS...Singh VK	2019
30	A Curious Case of Autoimmune Pancreatitis with IgG4-related Sclerosing Cholangitis. ( 31058036 )	Gonzalez HH...Sobrado J	2019
31	Pancreatic Solid Focal Lesions: Differential Diagnosis between Autoimmune Pancreatitis and Pancreatic Cancer. ( 31079114 )	Dite P...Kunovsky L	2019
32	The Challenge of Autoimmune Pancreatitis: A Portrayal From the Pediatric Perspective. ( 31090661 )	Pagliari D...Rigante D	2019
33	Type 1 autoimmune pancreatitis: a capsule-like rim surrounding the enlarged pancreas. ( 30107608 )	Kajihara Y	2019
34	Acquired hemophilia A associated with autoimmune pancreatitis with serum IgG4 elevation. ( 29582334 )	Narazaki T...Ogawa Y	2018
35	The use of magnetic resonance elastography in differentiating autoimmune pancreatitis from pancreatic ductal adenocarcinoma: A preliminary study. ( 30396645 )	Shi Y...Hong Y	2018
36	Qualitative and quantitative evaluation for morphological changes of the splenic artery in autoimmune pancreatitis: novel imaging findings for differentiation from pancreatic adenocarcinoma. ( 29948059 )	Toshima F...Gabata T	2018
37	Comparison of diagnostic performance between CT and MRI in differentiating non-diffuse-type autoimmune pancreatitis from pancreatic ductal adenocarcinoma. ( 29948075 )	Lee S...Lee SS	2018
38	Gastric varices and splenic vein obstruction during steroid treatment for autoimmune pancreatitis: A case report and literature review. ( 30142813 )	Juarez LA...Ruhnke GW	2018
39	There Is No Association between Coeliac Disease and Autoimmune Pancreatitis. ( 30149525 )	De Marchi G...Ciccocioppo R	2018
40	Autoimmune pancreatitis associated with retroperitoneal fibrosis mimicking cholangiocarcinoma. ( 30159151 )	Fanidou D...Filippou D	2018
41	Unique properties of IgG4 antibody and its clinical application in autoimmune pancreatitis. ( 30175675 )	Liu M...Hao M	2018
42	Disappearance of multiple pancreatic cysts after prednisolone treatment in a patient with autoimmune pancreatitis. ( 30214790 )	Kohisa J...Terai S	2018
43	Diagnosis, treatment and long-term outcome of autoimmune pancreatitis in Sweden. ( 30236651 )	Vujasinovic M...L?hr JM	2018
44	Management of Autoimmune Pancreatitis. ( 30241640 )	Madhani K...Farrell JJ	2018
45	Predictive Factors for Autoimmune Pancreatitis Relapse After 3 Years of Maintenance Therapy. ( 30286015 )	Nakamura A...Kawa S	2018
46	MR Imaging of Autoimmune Pancreatitis. ( 30376982 )	Hafezi-Nejad N...Zaheer A	2018
47	Mechanistic Insights into Autoimmune Pancreatitis and IgG4-Related Disease. ( 30401468 )	Watanabe T...Strober W	2018
48	Serum and histological IgG4-negative type 1 autoimmune pancreatitis. ( 30414073 )	Takano Y...Nagahama M	2018
49	The role of EUS-guided fine needle aspiration in autoimmune pancreatitis: a single center prospective study. ( 30422724 )	Cao L...Cheng B	2018
50	Autoimmune pancreatitis after nivolumab anti-programmed death receptor-1 treatment. ( 30454710 )	Dehghani L...Larger E	2018

Sources

Genes for Autoimmune Pancreatitis

Genes related to Autoimmune Pancreatitis (0 elite genes):

(show all 13)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	CA2	Carbonic Anhydrase 2	Protein Coding	23.84	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
2	PRSS1	Serine Protease 1	Protein Coding	22.73	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
3	CFTR	CF Transmembrane Conductance Regulator	Protein Coding	22.25	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
4	UBR2	Ubiquitin Protein Ligase E3 Component N-Recognin 2	Protein Coding	21.94	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
5	FCRL3	Fc Receptor Like 3	Protein Coding	21.84	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
6	ENO1	Enolase 1	Protein Coding	21.5	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
7	FOXP3	Forkhead Box P3	Protein Coding	21.3	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
8	TNFSF13B	TNF Superfamily Member 13b	Protein Coding	20.98	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
9	CTLA4	Cytotoxic T-Lymphocyte Associated Protein 4	Protein Coding	20.8	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
10	SPTAN1	Spectrin Alpha, Non-Erythrocytic 1	Protein Coding	20.74	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
11	IL10	Interleukin 10	Protein Coding	20.59	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
12	KCNA3	Potassium Voltage-Gated Channel Subfamily A Member 3	Protein Coding	20.51	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
13	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	20.44	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)

Sources

Variations for Autoimmune Pancreatitis

Sources

Expression for Autoimmune Pancreatitis

Search GEO for disease gene expression data for Autoimmune Pancreatitis.

Sources

Pathways for Autoimmune Pancreatitis

Pathways related to Autoimmune Pancreatitis according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	NF-kappaB Signaling ⁴	11.97	CTLA4 FOXP3 IL10 TNFSF13B
2	Allograft rejection ³⁸ ¹ Show member pathways Antigen processing and presentation ³⁸ Asthma ³⁸ Autoimmune thyroid disease ³⁸ CTL Mediated Apoptosis ⁶⁵ Graft-versus-host disease ³⁸ Intestinal immune network for IgA production ³⁸ THC Differentiation Pathway ⁶⁵ Type I diabetes mellitus ³⁸ Viral myocarditis ³⁸	11.76	CTLA4 FOXP3 HRAS IL10 TNFSF13B
3	Pancreatic secretion ³⁸	11.12	CA2 CFTR PRSS1
4	G-protein signaling_RhoB regulation pathway ²³	10.66	IL10 TNFSF13B UBR2

Sources

GO Terms for Autoimmune Pancreatitis

Biological processes related to Autoimmune Pancreatitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of B cell proliferation	GO:0030890	9.46	FCRL3 TNFSF13B
2	negative regulation of interferon-gamma production	GO:0032689	9.43	FOXP3 IL10
3	negative regulation of interleukin-6 production	GO:0032715	9.4	FOXP3 IL10
4	B cell homeostasis	GO:0001782	9.37	FOXP3 TNFSF13B
5	defense response to protozoan	GO:0042832	9.32	HRAS IL10
6	negative regulation of B cell proliferation	GO:0030889	9.26	CTLA4 IL10
7	regulation of regulatory T cell differentiation	GO:0045589	9.16	CTLA4 FOXP3
8	negative regulation of immune response	GO:0050777	8.96	CTLA4 FOXP3
9	negative regulation of T cell proliferation	GO:0042130	8.8	CTLA4 FOXP3 IL10

Sources

Sources for Autoimmune Pancreatitis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FDA Approved Drugs

²⁰ FMA

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ Genetics Home Reference

²⁷ GenomeRNAi

²⁸ GEO DataSets

²⁹ GO

³⁰ GTR

³¹ HGMD

³² HMDB

³³ HPO

³⁴ ICD10

³⁵ ICD10 via Orphanet

³⁶ ICD9CM

³⁷ IUPHAR

³⁸ KEGG

³⁹ LifeMap

⁴⁰ LncRNADisease

⁴¹ LOVD

⁴² MalaCards

⁴³ MedGen

⁴⁴ MedlinePlus

⁴⁵ MeSH

⁴⁶ MESH via Orphanet

⁴⁷ MGI

⁴⁸ miR2Disease

⁴⁹ NCBI Bookshelf

⁵⁰ NCI

⁵¹ NCIt

⁵² NDF-RT

⁵³ NIH Clinical Center

⁵⁴ NIH Rare Diseases

⁵⁵ NINDS

⁵⁶ Novoseek

⁵⁷ Novus Biologicals

⁵⁸ OMIM

⁵⁹ OMIM via Orphanet

⁶⁰ Orphanet

⁶¹ PathCards

⁶² PharmGKB

⁶³ PubMed

⁶⁴ PubMed Health

⁶⁵ QIAGEN

⁶⁶ R&D Systems

⁶⁷ Reactome

⁶⁸ Sino Biological

⁶⁹ SNOMED-CT

⁷⁰ SNOMED-CT via HPO

⁷¹ SNOMED-CT via Orphanet

⁷² TGDB

⁷³ Tocris

⁷⁴ UMLS

⁷⁵ UMLS via Orphanet

⁷⁶ UniProtKB/Swiss-Prot

⁷⁷ Wikipedia