Aliases & Classifications for Autonomic Dysfunction

MalaCards integrated aliases for Autonomic Dysfunction:

Name: Autonomic Dysfunction 54
Autonomic Nervous System Disorders 73
Autonomic Disorder 55

Classifications:



External Ids:

UMLS 73 C1145628

Summaries for Autonomic Dysfunction

NINDS : 54 Dysautonomia refers to a disorder of autonomic nervous system (ANS) function that generally involves failure of the sympathetic or parasympathetic components of the ANS, but dysautonomia involving excessive or overactive ANS actions also can occur. Dysautonomia can be local, as in reflex sympathetic dystrophy, or generalized, as in pure autonomic failure. It can be acute and reversible, as in Guillain-Barre syndrome, or chronic and progressive. Several common conditions such as diabetes and alcoholism can include dysautonomia. Dysautonomia also can occur as a primary condition or in association with degenerative neurological diseases such as Parkinson's disease. Other diseases with generalized, primary dysautonomia include multiple system atrophy and familial dysautonomia. Hallmarks of generalized dysautonomia due to sympathetic failure are impotence (in men) and a fall in blood pressure during standing (orthostatic hypotension). Excessive sympathetic activity can present as hypertension or a rapid pulse rate.

MalaCards based summary : Autonomic Dysfunction, also known as autonomic nervous system disorders, is related to neuropathy, hereditary sensory and autonomic, type iia and multiple system atrophy 1, and has symptoms including back pain, constipation and diarrhea. An important gene associated with Autonomic Dysfunction is ECE1 (Endothelin Converting Enzyme 1), and among its related pathways/superpathways are Neuroscience and Parkinsons Disease Pathway. The drugs Lidocaine and Midodrine have been mentioned in the context of this disorder. Affiliated tissues include heart, spinal cord and brain, and related phenotypes are behavior/neurological and growth/size/body region

Wikipedia : 76 Dysautonomia or autonomic dysfunction is a condition in which the autonomic nervous system (ANS) does... more...

Related Diseases for Autonomic Dysfunction

Diseases related to Autonomic Dysfunction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 281)
# Related Disease Score Top Affiliating Genes
1 neuropathy, hereditary sensory and autonomic, type iia 30.8 RETREG1 SCN9A WNK1
2 multiple system atrophy 1 29.8 DBH SNCA
3 pure autonomic failure 29.4 DBH SNCA
4 orthostatic intolerance 29.3 DBH ECE1
5 hypertension, essential 28.8 DBH ECE1 WNK1
6 neuropathy 28.2 RETREG1 SCN9A SPTLC1 WNK1
7 parkinson disease, late-onset 27.8 DBH SNCA UCHL1
8 autonomic neuropathy 27.6 RETREG1 SCN9A SPTLC1 WNK1
9 hirschsprung disease, cardiac defects, and autonomic dysfunction 12.5
10 pitt-hopkins syndrome 11.5
11 dysautonomia 11.2
12 neuropathy, hereditary sensory and autonomic, type iii 11.2
13 neuroleptic malignant syndrome 11.1
14 indifference to pain, congenital, autosomal recessive 10.8
15 neuronal intranuclear inclusion disease 10.8
16 aromatic l-amino acid decarboxylase deficiency 10.8
17 autonomic nervous system disease 10.8
18 neuropathy, hereditary sensory and autonomic, type ia 10.8
19 parkinson disease 4, autosomal dominant 10.8
20 opsoclonus-myoclonus syndrome 10.8
21 neuropathy, hereditary sensory and autonomic, type iib 10.8
22 paroxysmal extreme pain disorder 10.8
23 myoclonic encephalopathy of infants 10.8
24 spastic paraplegia 2, x-linked 10.8
25 neuropathy, hereditary sensory and autonomic, type ic 10.8
26 perry syndrome 10.8
27 parkinson disease 5, autosomal dominant 10.8
28 riboflavin transporter deficiency 10.8
29 harlequin syndrome 10.7
30 multiple sclerosis 10.2
31 diabetes mellitus 10.1
32 fibromyalgia 10.0
33 diabetes mellitus, noninsulin-dependent 10.0
34 dementia 10.0
35 epilepsy 10.0
36 cocaine abuse 10.0 DBH SNCA
37 sleep apnea 9.9
38 scleroderma, familial progressive 9.9
39 spinal cord injury 9.9
40 aging 9.9
41 liver disease 9.9
42 cerebritis 9.9
43 apnea, obstructive sleep 9.9
44 polyneuropathy 9.9
45 arthritis 9.9
46 brain injury 9.9
47 chagas disease 9.9
48 rheumatoid arthritis 9.9
49 sleep disorder 9.9
50 polycystic ovary syndrome 9.9

Graphical network of the top 20 diseases related to Autonomic Dysfunction:



Diseases related to Autonomic Dysfunction

Symptoms & Phenotypes for Autonomic Dysfunction

UMLS symptoms related to Autonomic Dysfunction:


back pain, constipation, diarrhea, headache, mydriasis, pain, rectal pain, sciatica, seizures, syncope, tremor, vomiting, chronic pain, lightheadedness, decrease in appetite, rectal tenesmus, warm skin, dry throat, palpitations - fluttering, pounding heart, syncope, effort, hyperemesis, anal pain, vomiting in newborn, blackout - symptom, vertigo/dizziness, increased sweating, vomiting alone, sleeplessness

MGI Mouse Phenotypes related to Autonomic Dysfunction:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.85 DBH RETREG1 SCN9A SNCA SPTLC1 UCHL1
2 growth/size/body region MP:0005378 9.8 DBH ECE1 SCN9A SNCA UCHL1 WNK1
3 integument MP:0010771 9.73 DBH ECE1 RETREG1 SCN9A SNCA UCHL1
4 mortality/aging MP:0010768 9.7 DBH ECE1 SCN9A SNCA SPTLC1 UCHL1
5 nervous system MP:0003631 9.56 DBH ECE1 RETREG1 SCN9A SNCA SPTLC1
6 renal/urinary system MP:0005367 8.92 SCN9A SNCA UCHL1 WNK1

Drugs & Therapeutics for Autonomic Dysfunction

Drugs for Autonomic Dysfunction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 504)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lidocaine Approved, Vet_approved Phase 4,Not Applicable 137-58-6 3676
2
Midodrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 133163-28-7, 42794-76-3 4195
3
Bupivacaine Approved, Investigational Phase 4,Phase 3,Not Applicable 2180-92-9, 38396-39-3 2474
4
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-61-6, 62-31-7 681
5
Acetylcholine Approved Phase 4,Not Applicable 51-84-3 187
6
Risperidone Approved, Investigational Phase 4 106266-06-2 5073
7
Triamcinolone Approved, Vet_approved Phase 4,Phase 3 124-94-7 31307
8
Metoprolol Approved, Investigational Phase 4,Phase 2,Phase 1,Not Applicable 37350-58-6, 51384-51-1 4171
9
Zolpidem Approved Phase 4,Not Applicable 82626-48-0 5732
10
Furosemide Approved, Vet_approved Phase 4,Not Applicable 54-31-9 3440
11
Indapamide Approved Phase 4 26807-65-8 3702
12
Fludrocortisone Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 127-31-1 31378
13
Gabapentin Approved, Investigational Phase 4,Not Applicable 60142-96-3 3446
14
Bisoprolol Approved Phase 4 66722-44-9 2405
15
Propranolol Approved, Investigational Phase 4,Phase 1,Phase 2,Not Applicable,Early Phase 1 525-66-6 4946
16
Levodopa Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 59-92-7 6047
17
Benzocaine Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 1994-09-7, 94-09-7 2337
18
Irbesartan Approved, Investigational Phase 4 138402-11-6 3749
19
Droxidopa Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 23651-95-8 443940
20
gamma-Aminobutyric acid Approved, Investigational Phase 4,Not Applicable 56-12-2 119
21
Acetylcarnitine Approved, Investigational Phase 4 3040-38-8 1
22
Vildagliptin Approved, Investigational Phase 4 274901-16-5 6918537
23
Vitamin C Approved, Nutraceutical Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1 50-81-7 5785 54670067
24
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4,Not Applicable 1406-16-2
25 tannic acid Approved, Nutraceutical Phase 4,Phase 2,Phase 3,Not Applicable
26
Vitamin D3 Approved, Nutraceutical Phase 4 67-97-0 6221 5280795
27
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3 59-30-3 6037
28 triamcinolone acetonide Phase 4,Phase 3
29 Analgesics Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
30 abobotulinumtoxinA Phase 4,Not Applicable
31 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
32 Adrenergic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
33 Micronutrients Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1
34 Adrenergic Agonists Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
35 Adrenergic alpha-Agonists Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
36 Adrenergic Antagonists Phase 4,Phase 2,Phase 1,Not Applicable,Early Phase 1
37 Adrenergic beta-1 Receptor Antagonists Phase 4,Phase 2,Phase 1,Not Applicable
38 Adrenergic beta-Antagonists Phase 4,Phase 2,Phase 1,Not Applicable,Early Phase 1
39 Cholinergic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
40 GABA Agents Phase 4,Early Phase 1,Not Applicable
41 GABA Agonists Phase 4
42 Serotonin Agents Phase 4,Phase 2,Phase 1,Not Applicable,Early Phase 1
43 GABA-A Receptor Agonists Phase 4
44 Serotonin Antagonists Phase 4
45 Neuromuscular Agents Phase 4,Not Applicable
46 Sympatholytics Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
47 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
48 Anesthetics Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
49 Trace Elements Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1
50 Anesthetics, Local Phase 4,Phase 3,Phase 1,Not Applicable

Interventional clinical trials:

(show top 50) (show all 538)
# Name Status NCT ID Phase Drugs
1 Risperidone and Zotepine in the Treatment of Delirium Unknown status NCT00622011 Phase 4 Risperidone and Zolpidem for delirium
2 Closed Loop Stimulation for Neuromediated Syncope (SPAIN Study) Unknown status NCT01621464 Phase 4
3 Botulinum A Toxin in Patients With Parkinson's Disease Unknown status NCT00822913 Phase 4 Intravesical injection of Botulinum A toxin
4 Botox for Neurogenic Detrusor Overactivity and the Prevention of Autonomic Dysreflexia Following SCI Unknown status NCT02298660 Phase 4 BOTOX
5 Duodenal Levodopa Infusion, Quality of Life and Autonomic Nervous System in Parkinson's Disease Completed NCT00914134 Phase 4 Levodopa infusion
6 Heart Rate Variability in Fibromyalgia - Effects of Strengthening Exercises Completed NCT02004405 Phase 4
7 Using Propranolol in Traumatic Brain Injury to Reduce Sympathetic Storm Phenomenon Completed NCT03401515 Phase 4 Propranolol Hydrochloride 1 MG/ML
8 Effect of Rotigotine Patch Treatment on Cardiovascular Markers in Idiopathic Restless Legs Syndrome Completed NCT01823770 Phase 4 Rotigotine;Placebo patchs
9 Sympathetic Heart Innervation in Patients With Tako-Tsubo Cardiomyopathy Completed NCT01524861 Phase 4 Placebo;alpha-lipoic acid;L-acetyl carnitine
10 Propranolol to Treat Fainting Due to Sympathoadrenal Imbalance Completed NCT00060866 Phase 4 Propranolol
11 Prophylactic Administration of Vitamin C in Wrist Fractures Completed NCT00296868 Phase 4 ascorbic acid (vitamin C) versus placebo
12 Treatment and Prognosis of Neurogenic Orthostatic Hypotension : A Prospective Randomized Study Completed NCT02308124 Phase 4 Midodrine;Pyridostigmine Bromide;Midodrine + pyridostigmine
13 Tilt-Table Study of the Clinical Efficacy of Midodrine in Symptomatic Orthostatic Hypotension Completed NCT01518946 Phase 4 Midodrine HCl;Placebo
14 Clinical Efficacy of Midodrine in Symptomatic Orthostatic Hypotension Completed NCT01515865 Phase 4 Midodrine HCl;Placebo
15 Study to Assess the Benefit of Midodrine in the Treatment of Patients With Neurogenic Orthostatic Hypotension Completed NCT00555880 Phase 4 Midodrine hydrochloride;Placebo
16 A Study for Patients With Neurogenic Orthostatic Hypotension Completed NCT00046475 Phase 4 Midodrine Hydrochloride
17 Effect of Medical Treatment and Prognosis of Postural Orthostatic Tachycardia Syndrome (POTS) Completed NCT02171988 Phase 4 Propranolol;Bisoprolol;Propranolol+pyridostigmine;Bisoprolol+pyridostgmine
18 Clinical Trial for the Prevention of Vasovagal Syncope Completed NCT00118482 Phase 4 fludrocortisone acetate
19 Renal Denervation in Diabetic Nephropathy Completed NCT01588795 Phase 4 Standardized antiproteinuric medication regimen includes an angiotensin receptor blocker , a diuretic , 25OH vitamin D3 and a statin
20 Restore Claims Characterization Study Completed NCT00200122 Phase 4
21 High Frequency Stimulation Trials in Patients With Precision Spinal Cord Stimulator System Completed NCT02265848 Phase 4
22 A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions Completed NCT00904202 Phase 4 Placebo Capsules + Placebo Patch;Placebo capsules + Lidoderm®;Gabapentin + Placebo;Gabapentin + Lidoderm®;Gabapentin 300 mg capsules 1800 mg/day + placebo patch;Gabapentin 1800 mg/day + Lidoderm patch
23 Sustained Effect of Droxidopa in Symptomatic Neurogenic Orthostatic Hypotension Recruiting NCT02586623 Phase 4 Droxidopa capsules;Placebo capsules
24 Effects of DPP4 Inhibitor Versus SGLT2 Inhibitor Recruiting NCT03178591 Phase 4 vildagliptin;Dapagliflozin
25 Efficacy and Safety of Midodrine and Atomoxetine for Neurogenic OH Recruiting NCT03350659 Phase 4 Midodrine;Atomoxetine
26 Dawn Simulation and Postural Hypotension Recruiting NCT02632318 Phase 4
27 Assessment of Metoprolol in the Prevention of Vasovagal Syncope in Aging Subjects Recruiting NCT02123056 Phase 4 Metoprolol;Matching Placebo
28 Assessment of Midodrine in the Prevention of Vasovagal Syncope: The Prevention of Syncope Trial IV Recruiting NCT01456481 Phase 4 midodrine hydrochloride;matching placebo
29 Tolerability of Suprascapular and Median Nerve Blocks for the Treatment of Shoulder-hand Syndrome Recruiting NCT03291197 Phase 4 Suprascapular and median nerve blocks
30 Rotigotine Effect on Nocturnal Hypokinesia Compares to Placebo Control: A Quantitative Assessment by Wearable Sensors Active, not recruiting NCT03098368 Phase 4 Rotigotine;Placebo
31 MP Diagnostics HTLV Blot 2.4 Post-Market Clinical Study Active, not recruiting NCT03226119 Phase 4
32 Brain Perfusion & Oxygenation in Parkinson's Disease With NOH Not yet recruiting NCT03229174 Phase 4 Droxidopa;Placebo
33 A Phase IV Study in Subjects With Neurogenic Orthostatic Hypotension Terminated NCT00046163 Phase 4 midodrine hydrochloride (ProAmatine®)
34 Clinical Trial on the Effectiveness of Traditional Chinese Medicinal Mixture in Parkinson Disease Unknown status NCT00629161 Phase 2, Phase 3 Traditional Chinese Medicinal Mixture (composed of Roucongrong and adjuvant);placebo
35 Surgical Treatment Of Complex Regional Pain Syndrome Type II (CRPS II) Unknown status NCT01392599 Phase 3
36 Acupuncture for Post-stroke Shoulder-hand Syndrome Unknown status NCT02011854 Phase 2, Phase 3
37 RCT :Thoracic Sympathetic Block for the Treatment of Complex Regional Pain Syndrome I of the Upper Limb Unknown status NCT01612364 Phase 3
38 Analysis of Photoplethysmographic Signal in Lumbar Sympathetic Block Unknown status NCT01134289 Phase 3
39 Intravenous Immunoglobulins in Complex-regional Pain Syndrome Unknown status NCT00949065 Phase 3
40 The Effects Of Bronchodilator Therapy On Respiratory And Autonomic Function In Patients With Familial Dysautonomia Completed NCT01987219 Phase 3 Albuterol-sulphate;Ipratropium-bromide
41 Carbidopa for the Treatment of Nausea and Vomiting in Familial Dysautonomia Completed NCT01212484 Phase 3 Carbidopa;Placebo
42 Clinical Trial to Measure the Maximun HR After ReConnect ® Supplementation vs. Placebo in CFS. Completed NCT02063126 Phase 2, Phase 3
43 Safety and Efficacy Study of Fx-1006A in Patients With Familial Amyloidosis Completed NCT00409175 Phase 2, Phase 3 Fx-1006A;Placebo
44 The Effect of Diet on Chronic Inflammation and Related Disorders Following Spinal Cord Injury Completed NCT02099890 Phase 3
45 Evaluating the Effectiveness of Intravenous Immunoglobulin Therapy in Autoimmune Autonomic Ganglionopathy Completed NCT01522235 Phase 2, Phase 3 Double blinded IVIg
46 Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) (Droxi-304) Completed NCT01132326 Phase 3 Droxidopa
47 A Clinical Study for Patients With Neurogenic Orthostatic Hypotension (NOH) Using Droxidopa Completed NCT00782340 Phase 3 Placebo;Droxidopa
48 Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) Completed NCT00633880 Phase 3 Placebo;Droxidopa
49 Clinical Trial on the Effectiveness of Herbal Medicinal Mixture in Parkinson Disease Completed NCT00656253 Phase 2, Phase 3 Herbal Medicinal Mixture (Roucongrong, Heshouwu etc.);Placebo
50 Open-Label Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) Completed NCT00738062 Phase 3 Droxidopa;Placebo

Search NIH Clinical Center for Autonomic Dysfunction

Genetic Tests for Autonomic Dysfunction

Anatomical Context for Autonomic Dysfunction

MalaCards organs/tissues related to Autonomic Dysfunction:

41
Heart, Spinal Cord, Brain, Testes, Liver, Cortex, Bone

Publications for Autonomic Dysfunction

Articles related to Autonomic Dysfunction:

(show top 50) (show all 731)
# Title Authors Year
1
The Longest Obstructive Apnea You Have Ever Seen: A Patient With New-Onset Autonomic Dysfunction. ( 29734980 )
2018
2
Cardiovascular Autonomic Dysfunction: Link Between Multiple Sclerosis Osteoporosis and Neurodegeneration. ( 29429076 )
2018
3
Autonomic Dysfunction Predicts Clinical Outcomes After Acute Ischemic Stroke: A Prospective Observational Study. ( 29203690 )
2018
4
The Spectrum of Autonomic Dysfunction in Myasthenic Crisis. ( 29720797 )
2018
5
Chronic obstructive pulmonary disease-induced autonomic dysfunction may be associated with cerebral blood flow regulation and brain function. ( 29978508 )
2018
6
Bitemporal seizure spread and its effect on autonomic dysfunction. ( 29803947 )
2018
7
Increased cardiac stiffness is associated with autonomic dysfunction in patients with temporal lobe epilepsy. ( 29697139 )
2018
8
Pulse pressure amplification and cardiac autonomic dysfunction in patients with type 2 diabetes mellitus. ( 29789692 )
2018
9
Higher body mass index predicts cardiac autonomic dysfunction: A longitudinal study in adolescent type 1 diabetes. ( 29383813 )
2018
10
Central or peripheral autonomic dysfunction in Parkinson disease: Does it matter? ( 29728530 )
2018
11
Impaired cortical autonomic responses during sympathetic activation in Neurogenic Orthostatic Hypotension characterized by post-ganglionic autonomic dysfunction. ( 29901433 )
2018
12
Reply to: "Autonomic dysfunction in Parkinson's disease: The hidden game changer?" ( 29756304 )
2018
13
Symptoms of Autonomic Dysfunction in Systemic Sclerosis Assessed by the COMPASS-31 Questionnaire. ( 29907667 )
2018
14
No sympathy for the hypoxic: the role of fetal oxygenation in autonomic dysfunction. ( 29774552 )
2018
15
Cardiovascular Autonomic Dysfunction in Patients with Cancer. ( 29971575 )
2018
16
Autonomic dysfunction in Parkinson's disease: The hidden game changer? ( 29756259 )
2018
17
Cardiovascular autonomic dysfunction in sudden infant death syndrome. ( 29299712 )
2018
18
Atrial Arrhythmias and Autonomic Dysfunction in Rats Exposed to Chronic Intermittent Hypoxia. ( 29424572 )
2018
19
Effects of autonomic dysfunction on exercise tolerance in systemic sclerosis patients without clinical and instrumental evidence of cardiac and pulmonary involvement. ( 29745872 )
2018
20
Managing Postural Hypotension in Diabetic Autonomic Dysfunction When Adrenergic Drugs are Contraindicated: Case Report and Review of Literature. ( 29541560 )
2018
21
Disrupted hypothalamic functional connectivity in patients with PD and autonomic dysfunction. ( 29728527 )
2018
22
Acute interruption of treatment with nandrolone decanoate is not sufficient to reverse cardiac autonomic dysfunction and ventricular repolarization disturbances in rats. ( 29366731 )
2018
23
The association of cardiovascular autonomic dysfunction and the prediction of COPD can be explained by neurohumoral activation. ( 29880542 )
2018
24
Patients with primary restless legs syndrome have higher prevalence of autonomic dysfunction and irritable bowel syndrome. ( 29372261 )
2018
25
Autonomic dysfunction in Parkinson's disease and other synucleinopathies: Introduction to the series. ( 29436737 )
2018
26
Circadian rhythm abnormalities and autonomic dysfunction in patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis. ( 29874259 )
2018
27
Markers of cardiovascular autonomic dysfunction predict COPD in middle-aged subjects. ( 29419441 )
2018
28
Progressive multiple sclerosis patients have a higher burden of autonomic dysfunction compared to relapsing remitting phenotype. ( 29885648 )
2018
29
Autonomic dysfunction predicts poor outcome in stroke: Updates on recent autonomic research. ( 29305815 )
2018
30
Neuropathology of autonomic dysfunction in synucleinopathies. ( 29297596 )
2018
31
Carotid Body Ablation: a New Target to Address Central Autonomic Dysfunction. ( 29789952 )
2018
32
Cardiovascular autonomic dysfunction in patients with idiopathic diabetes insipidus. ( 29081004 )
2018
33
Lateral medullary infarction with cardiovascular autonomic dysfunction: an unusual presentation with review of the literature. ( 29368226 )
2018
34
A Case of Recurrent Hypersomnia With Autonomic Dysfunction. ( 28633719 )
2017
35
Severity of traumatic brain injury correlates with long-term cardiovascular autonomic dysfunction. ( 28770375 )
2017
36
REM sleep behavior disorder, autonomic dysfunction and synuclein-related neurodegeneration: where do we stand? ( 28871332 )
2017
37
Fat intake and cardiac autonomic dysfunction in obese children: What is the relationship? ( 28673780 )
2017
38
Dante Alighieri: evidence for sleep disorder-related cardiac autonomic dysfunctions. ( 28000594 )
2017
39
Autonomic dysfunction plays a decisive role in the arrhythmia initiation, whereas metabolic disorders facilitate further atrial remodeling in antipsychotic-related atrial fibrillation. ( 28712564 )
2017
40
A novel mutation in GMPPA in siblings with apparent intellectual disability, epilepsy, dysmorphism, and autonomic dysfunction. ( 28574218 )
2017
41
Hereditary angioedema: Assessing the hypothesis for underlying autonomic dysfunction. ( 29107952 )
2017
42
Acute onset autonomic dysfunction and orthostatic syncope as an early manifestation of HIV infection. ( 28856462 )
2017
43
Pupillary autonomic dysfunction in patients with ANCA-associated vasculitis. ( 28864843 )
2017
44
Implantable cardiac monitors in high-risk post-infarction patients with cardiac autonomic dysfunction and moderately reduced left ventricular ejection fraction: Design and rationale of the SMART-MI trial. ( 28760211 )
2017
45
Orthostatic Hypotension in Patients With Left Ventricular Assist Devices: Acquired Autonomic Dysfunction. ( 28799950 )
2017
46
Paediatric breath-holding spells are associated with autonomic dysfunction and iron deficiency may play a role. ( 29210110 )
2017
47
Arterial Stiffness and Cardiovascular Autonomic Dysfunction in Patients with Parkinson's Disease. ( 27784025 )
2017
48
Peduncular Hallucinosis and Autonomic Dysfunction in Anti-Aquaporin-4 Antibody Syndrome. ( 28926419 )
2017
49
Mutations in MYO1H cause a recessive form of central hypoventilation with autonomic dysfunction. ( 28779001 )
2017
50
Autonomic Dysfunction after Mild Traumatic Brain Injury. ( 28800081 )
2017

Variations for Autonomic Dysfunction

Expression for Autonomic Dysfunction

Search GEO for disease gene expression data for Autonomic Dysfunction.

Pathways for Autonomic Dysfunction

Pathways related to Autonomic Dysfunction according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.46 DBH SCN9A SNCA UCHL1
2 11.08 SNCA UCHL1
3 10.46 SNCA UCHL1

GO Terms for Autonomic Dysfunction

Cellular components related to Autonomic Dysfunction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane GO:0016020 9.23 DBH ECE1 RETREG1 SCN9A SNCA SPTLC1

Biological processes related to Autonomic Dysfunction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of receptor recycling GO:0001921 8.96 ECE1 SNCA
2 sensory perception of pain GO:0019233 8.8 RETREG1 SCN9A UCHL1

Molecular functions related to Autonomic Dysfunction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 copper ion binding GO:0005507 8.62 DBH SNCA

Sources for Autonomic Dysfunction

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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