MCID: ATN003
MIFTS: 25

Autonomic Nervous System Neoplasm

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Autonomic Nervous System Neoplasm

MalaCards integrated aliases for Autonomic Nervous System Neoplasm:

Name: Autonomic Nervous System Neoplasm 12 15 70
Tumor of Autonomic Nervous System 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2621
NCIt 50 C5112
UMLS 70 C1332356

Summaries for Autonomic Nervous System Neoplasm

Disease Ontology : 12 A peripheral nervous system neoplasm that is located in the autonomic nervous system.

MalaCards based summary : Autonomic Nervous System Neoplasm, also known as tumor of autonomic nervous system, is related to neuroblastoma and central nervous system benign neoplasm. An important gene associated with Autonomic Nervous System Neoplasm is H2AC18 (H2A Clustered Histone 18), and among its related pathways/superpathways are MicroRNAs in cancer and Alzheimers Disease. Affiliated tissues include autonomic nervous system.

Related Diseases for Autonomic Nervous System Neoplasm

Diseases in the Autonomic Nervous System Neoplasm family:

Autonomic Nervous System Benign Neoplasm

Diseases related to Autonomic Nervous System Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 195)
# Related Disease Score Top Affiliating Genes
1 neuroblastoma 32.5 MYCN MIR34A MIR338 MIR21 MIR181A1 MIR17
2 central nervous system benign neoplasm 10.6 MYCN MIR34A KDM4C H2AC18
3 muscle cancer 10.6 MYCN MIR9-1 MIR199A1 H2AC18
4 chromosomal deletion syndrome 10.6 MIR9-1 MIR17 KDM4C H2AC18
5 fetal alcohol spectrum disorder 10.6 MIR9-1 KDM4C H2AC18
6 suppression of tumorigenicity 12 10.6 MYCN MIR199A1 KDM4C H2AC18
7 testicular disease 10.6 MIR199A1 MIR181A1 KDM4C H2AC18
8 pleural disease 10.6 MIR199A1 MIR17 MIR125A H2AC18
9 fetal alcohol syndrome 10.6 MIR9-1 KDM4C H2AC18
10 uveal disease 10.6 MIR9-1 MIR199A1 MIR125A H2AC18
11 miyoshi muscular dystrophy 1 10.6 MIR34A MIR335 MIR21
12 chromosomal duplication syndrome 10.6 MIR9-1 MIR126 KDM4C H2AC18
13 intestinal benign neoplasm 10.6 MIR21 MIR20A MIR199A1 MIR17 H2AC18
14 gastrointestinal system benign neoplasm 10.6 MIR21 MIR20A MIR199A1 MIR17 H2AC18
15 mature t-cell and nk-cell lymphoma 10.6 MIR199A1 MIR17 MIR126 KDM4C H2AC18
16 tonsil cancer 10.6 MIR338 MIR199A1 H2AC18
17 in situ carcinoma 10.6 MIR181A1 MIR17 MIR126 H2AC18
18 bronchial disease 10.6 MIR21 MIR17 MIR126 H2AC18
19 melanoma in congenital melanocytic nevus 10.6 MIR199A1 KDM4C H2AC18
20 colonic benign neoplasm 10.6 MIR20A KDM4C H2AC18
21 germ cell cancer 10.6 MIR9-1 MIR199A1 KDM4C H2AC18
22 heart valve disease 10.6 MIR21 MIR199A1 MIR17 MIR126 H2AC18
23 primary mediastinal b-cell lymphoma 10.6 MIR9-1 MIR181A1 KDM4C
24 tongue disease 10.6 MIR21 MIR199A1 MIR181A1 MIR17
25 intrinsic cardiomyopathy 10.6 MIR21 MIR199A1 MIR126 H2AC18
26 oropharynx cancer 10.6 MIR9-1 MIR199A1 H2AC18
27 aortic valve disease 2 10.6 MIR34A MIR21 MIR199A1 MIR17 MIR126
28 ocular cancer 10.6 MIR9-1 MIR199A1 MIR17 MIR125A KDM4C H2AC18
29 bile duct cancer 10.6 MIR9-1 MIR21 MIR199A1 MIR17 KDM4C H2AC18
30 chromosome 16p13.3 deletion syndrome, proximal 10.6 MIR9-1 KDM4C H2AC18
31 muscular disease 10.6 MIR9-1 MIR21 MIR199A1 MIR126 H2AC18
32 eye degenerative disease 10.5 MIR335 MIR17 KDM4C H2AC18
33 chromosomal disease 10.5 MIR9-1 MIR21 MIR17 MIR126 KDM4C H2AC18
34 blood protein disease 10.5 MIR17 MIR126 H2AC18
35 feingold syndrome 1 10.5 MYCN MIR20A MIR17
36 thyroid gland disease 10.5 MIR9-1 MIR199A1 MIR181A1 MIR17 MIR125A H2AC18
37 skeletal muscle cancer 10.5 MYCN MIR199A1 H2AC18
38 retroperitoneal neuroblastoma 10.5 MYCN MIR34A
39 muscle tissue disease 10.5 MIR9-1 MIR199A1 MIR126 H2AC18
40 germ cell and embryonal cancer 10.5 MIR9-1 KDM4C H2AC18
41 melanoma, uveal 10.5 MIR9-1 MIR199A1 MIR149 MIR125A H2AC18
42 mouth disease 10.5 MIR9-1 MIR21 MIR181A1 MIR17 MIR125A H2AC18
43 ovarian serous carcinoma 10.5 MIR27A MIR21 MIR20A MIR199A1 MIR125A
44 aortic disease 10.5 MIR21 MIR199A1 MIR17 MIR126
45 microvascular complications of diabetes 5 10.5 MIR21 MIR20A MIR126 H2AC18
46 retinal vascular disease 10.5 MIR21 MIR20A MIR199A1 MIR17 MIR126 H2AC18
47 cerebral arterial disease 10.5 MIR199A1 MIR181A1 MIR125A
48 autoimmune disease of the nervous system 10.5 MIR9-1 MIR27A MIR126 MIR125A H2AC18
49 bile duct adenocarcinoma 10.5 MIR9-1 MIR21 MIR199A1 MIR17 MIR125A KDM4C
50 brain cancer 10.5 MYCN MIR9-1 MIR21 KDM4C H2AC18

Graphical network of the top 20 diseases related to Autonomic Nervous System Neoplasm:



Diseases related to Autonomic Nervous System Neoplasm

Symptoms & Phenotypes for Autonomic Nervous System Neoplasm

Drugs & Therapeutics for Autonomic Nervous System Neoplasm

Search Clinical Trials , NIH Clinical Center for Autonomic Nervous System Neoplasm

Genetic Tests for Autonomic Nervous System Neoplasm

Anatomical Context for Autonomic Nervous System Neoplasm

The Foundational Model of Anatomy Ontology organs/tissues related to Autonomic Nervous System Neoplasm:

19
Autonomic Nervous System

Publications for Autonomic Nervous System Neoplasm

Variations for Autonomic Nervous System Neoplasm

Expression for Autonomic Nervous System Neoplasm

Search GEO for disease gene expression data for Autonomic Nervous System Neoplasm.

Pathways for Autonomic Nervous System Neoplasm

Pathways related to Autonomic Nervous System Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.89 MIR9-1 MIR34C MIR34A MIR335 MIR27A MIR21
2 11.61 MIR9-1 MIR34C MIR323A MIR21 MIR181A1 MIR125A
3 11.48 MIR34C MIR338 MIR20A MIR17
4 11.16 MIR542 MIR34C MIR27A MIR181A1
5 11.08 MIR9-1 MIR199A1 MIR181A1

GO Terms for Autonomic Nervous System Neoplasm

Cellular components related to Autonomic Nervous System Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.7 MIR338 MIR335 MIR323A MIR27A MIR21 MIR20A
2 extracellular vesicle GO:1903561 9.17 MIR34A MIR27A MIR21 MIR20A MIR17 MIR126

Biological processes related to Autonomic Nervous System Neoplasm according to GeneCards Suite gene sharing:

(show all 31)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 10.03 MYCN MIR34A MIR21 MIR125A KDM4C
2 positive regulation of angiogenesis GO:0045766 9.88 MIR21 MIR20A MIR199A1 MIR126
3 negative regulation of inflammatory response GO:0050728 9.86 MIR20A MIR181A1 MIR149 MIR126
4 negative regulation of cell migration GO:0030336 9.85 MIR9-1 MIR34A MIR338 MIR21 MIR149 MIR126
5 positive regulation of osteoblast differentiation GO:0045669 9.8 MIR27A MIR21 MIR20A
6 negative regulation of protein kinase B signaling GO:0051898 9.79 MIR34C MIR34A MIR20A
7 negative regulation of interleukin-6 production GO:0032715 9.78 MIR338 MIR181A1 MIR149 MIR125A
8 negative regulation of cell migration involved in sprouting angiogenesis GO:0090051 9.77 MIR20A MIR199A1 MIR149
9 negative regulation of cardiac muscle cell apoptotic process GO:0010667 9.74 MIR21 MIR20A MIR199A1
10 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.73 MIR27A MIR21 MIR20A MIR17
11 miRNA mediated inhibition of translation GO:0035278 9.73 MIR9-1 MIR27A MIR21 MIR20A MIR181A1 MIR17
12 negative regulation of stress fiber assembly GO:0051497 9.72 MIR21 MIR20A MIR149
13 positive regulation of vascular endothelial cell proliferation GO:1905564 9.71 MIR27A MIR21 MIR126
14 negative regulation of sprouting angiogenesis GO:1903671 9.71 MIR34C MIR34A MIR20A MIR17
15 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:1903589 9.7 MIR27A MIR21 MIR126
16 negative regulation of amyloid precursor protein biosynthetic process GO:0042985 9.69 MIR323A MIR20A MIR17
17 negative regulation of low-density lipoprotein particle clearance GO:0010989 9.67 MIR27A MIR199A1 MIR17
18 positive regulation of endothelial cell differentiation GO:0045603 9.65 MIR21 MIR181A1
19 negative regulation of reactive oxygen species biosynthetic process GO:1903427 9.65 MIR21 MIR181A1
20 positive regulation of cardiac muscle cell apoptotic process GO:0010666 9.64 MIR34A MIR17
21 negative regulation of cytokine-mediated signaling pathway GO:0001960 9.64 MIR21 MIR125A
22 positive regulation of metalloendopeptidase activity GO:1904685 9.63 MIR21 MIR17
23 positive regulation of connective tissue replacement GO:1905205 9.63 MIR34C MIR34A MIR199A1
24 negative regulation of STAT cascade GO:1904893 9.62 MIR149 MIR125A
25 positive regulation of cardiac muscle hypertrophy in response to stress GO:1903244 9.62 MIR34C MIR20A MIR199A1 MIR17
26 negative regulation of interleukin-1-mediated signaling pathway GO:2000660 9.61 MIR27A MIR21
27 negative regulation of gene expression GO:0010629 9.61 MYCN MIR34A MIR338 MIR27A MIR21 MIR20A
28 negative regulation of vascular associated smooth muscle cell apoptotic process GO:1905460 9.6 MIR21 MIR17
29 positive regulation of pulmonary blood vessel remodeling GO:1905111 9.58 MIR20A MIR17
30 negative regulation of vascular endothelial growth factor production GO:1904046 9.55 MIR34A MIR20A MIR199A1 MIR17 MIR125A
31 gene silencing by miRNA GO:0035195 9.53 MIR9-1 MIR542 MIR34C MIR34A MIR338 MIR335

Molecular functions related to Autonomic Nervous System Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mRNA 3'-UTR binding GO:0003730 9.7 MIR9-1 MIR34A MIR338 MIR323A MIR27A MIR21
2 mRNA binding involved in posttranscriptional gene silencing GO:1903231 9.44 MIR9-1 MIR34A MIR338 MIR323A MIR27A MIR21
3 RNA polymerase II complex binding GO:0000993 9.33 MIR20A MIR126 MIR125A

Sources for Autonomic Nervous System Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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