MCID: ATN001
MIFTS: 21

Autonomic Peripheral Neuropathy

Categories: Neuronal diseases

Aliases & Classifications for Autonomic Peripheral Neuropathy

MalaCards integrated aliases for Autonomic Peripheral Neuropathy:

Name: Autonomic Peripheral Neuropathy 12 15
Peripheral Autonomic Nervous System Diseases 74

Classifications:



External Ids:

Disease Ontology 12 DOID:0060054
UMLS 74 C0750944

Summaries for Autonomic Peripheral Neuropathy

Disease Ontology : 12 A neuropathy that affects the autonomic nervous system and is characterized by urinary incontinence, gastrointestinal dysmotility, orthostatic hypotension, apneas, sweat disturbances and impotence.

MalaCards based summary : Autonomic Peripheral Neuropathy, also known as peripheral autonomic nervous system diseases, is related to peripheral nervous system disease and neuropathy. An important gene associated with Autonomic Peripheral Neuropathy is GAL (Galanin And GMAP Prepropeptide). Affiliated tissues include testes and pituitary.

Related Diseases for Autonomic Peripheral Neuropathy

Diseases related to Autonomic Peripheral Neuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 18)
# Related Disease Score Top Affiliating Genes
1 peripheral nervous system disease 29.5 TAC1 TTR
2 neuropathy 10.1
3 mononeuropathy 10.0 GAL TAC1
4 brachial plexus lesion 10.0 GAL TAC1
5 tsh producing pituitary tumor 10.0 GAL TTR
6 bladder neck obstruction 10.0 TAC1 TTR
7 retinitis pigmentosa 68 9.8 NPS TAC1
8 epicondylitis 9.8 NPS TAC1
9 dental pulp disease 9.8 NPS TAC1
10 indeterminate leprosy 9.8 NPS TAC1
11 neurodermatitis 9.8 NPS TAC1
12 causalgia 9.8 NPS TAC1
13 nasal cavity disease 9.7 NPS TAC1
14 carpal tunnel syndrome 9.7 TAC1 TTR
15 nose disease 9.7 NPS TAC1
16 perry syndrome 9.7 NPS TAC1
17 migraine with or without aura 1 9.7 NPS TAC1
18 autonomic nervous system disease 9.5 NPS TAC1 TTR

Graphical network of the top 20 diseases related to Autonomic Peripheral Neuropathy:



Diseases related to Autonomic Peripheral Neuropathy

Symptoms & Phenotypes for Autonomic Peripheral Neuropathy

Drugs & Therapeutics for Autonomic Peripheral Neuropathy

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Role of Indicator Test (Neuropad) in Detecting Diabetic Neuropathy Completed NCT00895440
2 Clinical Translation of 18F-Labeled Hydroxyphenethylguanidines Completed NCT02385877 Early Phase 1 [18F]4F-MHPG;[18F]3F-PHPG

Search NIH Clinical Center for Autonomic Peripheral Neuropathy

Genetic Tests for Autonomic Peripheral Neuropathy

Anatomical Context for Autonomic Peripheral Neuropathy

MalaCards organs/tissues related to Autonomic Peripheral Neuropathy:

42
Testes, Pituitary

Publications for Autonomic Peripheral Neuropathy

Articles related to Autonomic Peripheral Neuropathy:

# Title Authors Year
1
Autonomic peripheral neuropathy. ( 17324728 )
2007
2
Approach to a case of autonomic peripheral neuropathy. ( 17212023 )
2006
3
Autonomic peripheral neuropathy. ( 15811460 )
2005

Variations for Autonomic Peripheral Neuropathy

Expression for Autonomic Peripheral Neuropathy

Search GEO for disease gene expression data for Autonomic Peripheral Neuropathy.

Pathways for Autonomic Peripheral Neuropathy

GO Terms for Autonomic Peripheral Neuropathy

Cellular components related to Autonomic Peripheral Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 8.92 GAL NPS TAC1 TTR

Biological processes related to Autonomic Peripheral Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to lipopolysaccharide GO:0032496 9.32 NOS1 TAC1
2 response to hormone GO:0009725 9.26 NOS1 TAC1
3 positive regulation of synaptic transmission, GABAergic GO:0032230 9.16 NPS TAC1
4 neuropeptide signaling pathway GO:0007218 9.13 GAL NPS TAC1
5 positive regulation of action potential GO:0045760 8.62 NPS TAC1

Molecular functions related to Autonomic Peripheral Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.62 GAL TTR

Sources for Autonomic Peripheral Neuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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