Autosomal Recessive Epidermolytic Ichthyosis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Autosomal Recessive Epidermolytic Ichthyosis

MalaCards integrated aliases for Autosomal Recessive Epidermolytic Ichthyosis:

Name: Autosomal Recessive Epidermolytic Ichthyosis ⁵⁸

Arei ⁵⁸

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Skin diseases

See all MalaCards categories (disease lists)

Orphanet: ⁵⁸

Rare skin diseases

External Ids:

Orphanet ⁵⁸ ORPHA512103

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Summaries for Autosomal Recessive Epidermolytic Ichthyosis

MalaCards based summary : Autosomal Recessive Epidermolytic Ichthyosis, also known as arei, is related to ichthyosis and epidermolytic hyperkeratosis. An important gene associated with Autosomal Recessive Epidermolytic Ichthyosis is KRT10 (Keratin 10). Affiliated tissues include prostate.

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Related Diseases for Autosomal Recessive Epidermolytic Ichthyosis

Diseases in the Autosomal Dominant Epidermolytic Ichthyosis family:

Autosomal Recessive Epidermolytic Ichthyosis

Diseases related to Autosomal Recessive Epidermolytic Ichthyosis via text searches within MalaCards or GeneCards Suite gene sharing:

#	Related Disease	Score	Top Affiliating Genes
1	ichthyosis	29.8	KRT10-AS1 KRT10
2	epidermolytic hyperkeratosis	29.6	KRT10-AS1 KRT10
3	autosomal dominant epidermolytic ichthyosis	29.4	KRT10-AS1 KRT10
4	peeling skin syndrome 4	11.2
5	keratosis	10.2
6	prostatic hyperplasia, benign	9.9
7	prostatic hypertrophy	9.9
8	prostatic adenoma	9.9
9	erythroderma, ichthyosiform, congenital reticular	9.7	KRT10-AS1 KRT10
10	ichthyosis, cyclic, with epidermolytic hyperkeratosis	9.6	KRT10-AS1 KRT10

Graphical network of the top 20 diseases related to Autosomal Recessive Epidermolytic Ichthyosis:

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Symptoms & Phenotypes for Autosomal Recessive Epidermolytic Ichthyosis

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Drugs & Therapeutics for Autosomal Recessive Epidermolytic Ichthyosis

Search Clinical Trials , NIH Clinical Center for Autosomal Recessive Epidermolytic Ichthyosis

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Genetic Tests for Autosomal Recessive Epidermolytic Ichthyosis

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Anatomical Context for Autosomal Recessive Epidermolytic Ichthyosis

MalaCards organs/tissues related to Autosomal Recessive Epidermolytic Ichthyosis:

⁴⁰

Prostate

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Publications for Autosomal Recessive Epidermolytic Ichthyosis

Articles related to Autosomal Recessive Epidermolytic Ichthyosis:

#	Title	Authors	PMID	Year
1	Skin fragility caused by biallelic KRT10 mutations: an intriguing form of self-improving epidermolytic ichthyosis. ⁶¹	Frommherz L...Has C	31278741	2020
2	Epidermal barrier abnormalities in exfoliative ichthyosis with a novel homozygous loss-of-function mutation in CSTA. ⁶¹	Moosbrugger-Martinz V...Gruber R	25400170	2015
3	Association of G/A polymorphism, rs266882, in AREI region of the prostate-specific antigen gene with prostate cancer risk and clinicopathological features. ⁶¹	Samzadeh M...Ziaee SA	23235975	2012
4	Lethal autosomal recessive epidermolytic ichthyosis due to a novel donor splice-site mutation in KRT10. ⁶¹	Covaciu C...Castiglia D	20302579	2010
5	ARE-I polymorphism on PSA gene in prostate cancer patients of a Turkish population. ⁶¹	Kalay E...Isbir T	19414393	2009
6	PSA/KLK3 AREI promoter polymorphism alters androgen receptor binding and is associated with prostate cancer susceptibility. ⁶¹	Lai J...Clements JA	17151093	2007
7	Polymorphisms in the androgen receptor and the prostate-specific antigen genes and prostate cancer risk. ⁶¹	Salinas CA...Stanford JL	15810021	2005
8	Chimeric PSA enhancers exhibit augmented activity in prostate cancer gene therapy vectors. ⁶¹	Wu L...Carey M	11571582	2001

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Genes for Autosomal Recessive Epidermolytic Ichthyosis

Genes related to Autosomal Recessive Epidermolytic Ichthyosis (1 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubMed IDs
1	KRT10	Keratin 10	Protein Coding	357.41	Causative germline mutation ⁵⁸ GeneCards inferred via : Publications (show sections)	21271994 23957016
2	KRT10-AS1	KRT10 Antisense RNA 1	RNA Gene	7.41	GeneCards inferred via : Publications (show sections)

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Variations for Autosomal Recessive Epidermolytic Ichthyosis

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Expression for Autosomal Recessive Epidermolytic Ichthyosis

Search GEO for disease gene expression data for Autosomal Recessive Epidermolytic Ichthyosis.

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Pathways for Autosomal Recessive Epidermolytic Ichthyosis

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GO Terms for Autosomal Recessive Epidermolytic Ichthyosis

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Autosomal Recessive Epidermolytic Ichthyosis (AREI)

Aliases & Classifications for Autosomal Recessive Epidermolytic Ichthyosis

MalaCards integrated aliases for Autosomal Recessive Epidermolytic Ichthyosis:

Classifications:

External Ids:

Summaries for Autosomal Recessive Epidermolytic Ichthyosis

Related Diseases for Autosomal Recessive Epidermolytic Ichthyosis

Diseases in the Autosomal Dominant Epidermolytic Ichthyosis family:

Diseases related to Autosomal Recessive Epidermolytic Ichthyosis via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Autosomal Recessive Epidermolytic Ichthyosis:

Symptoms & Phenotypes for Autosomal Recessive Epidermolytic Ichthyosis

Drugs & Therapeutics for Autosomal Recessive Epidermolytic Ichthyosis

Genetic Tests for Autosomal Recessive Epidermolytic Ichthyosis

Anatomical Context for Autosomal Recessive Epidermolytic Ichthyosis

MalaCards organs/tissues related to Autosomal Recessive Epidermolytic Ichthyosis:

Publications for Autosomal Recessive Epidermolytic Ichthyosis

Articles related to Autosomal Recessive Epidermolytic Ichthyosis:

Genes for Autosomal Recessive Epidermolytic Ichthyosis

Genes related to Autosomal Recessive Epidermolytic Ichthyosis (1 elite genes):

Variations for Autosomal Recessive Epidermolytic Ichthyosis

Expression for Autosomal Recessive Epidermolytic Ichthyosis

Pathways for Autosomal Recessive Epidermolytic Ichthyosis

GO Terms for Autosomal Recessive Epidermolytic Ichthyosis

Sources for Autosomal Recessive Epidermolytic Ichthyosis