Avascular Necrosis (AVN)

Categories: Bone diseases, Rare diseases
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Aliases & Classifications for Avascular Necrosis

MalaCards integrated aliases for Avascular Necrosis:

Name: Avascular Necrosis 58 28 53 75
Avn 58


Orphanet: 58  
Rare systemic and rhumatological diseases
Rare bone diseases

External Ids:

Orphanet 58 ORPHA399164

Summaries for Avascular Necrosis

MalaCards based summary: Avascular Necrosis, also known as avn, is related to familial avascular necrosis of the femoral head and arthropathy. An important gene associated with Avascular Necrosis is COL2A1 (Collagen Type II Alpha 1 Chain). The drugs Tacrine and Bupivacaine have been mentioned in the context of this disorder. Affiliated tissues include bone, bone marrow and endothelial, and related phenotypes are cardiovascular system and respiratory system

Wikipedia: 75 Avascular necrosis (AVN), also called osteonecrosis or bone infarction, is death of bone tissue due to... more...

Related Diseases for Avascular Necrosis

Diseases in the Avascular Necrosis family:

Rare Hereditary Disease with Avascular Necrosis Secondary Avascular Necrosis
Primary Avascular Necrosis

Diseases related to Avascular Necrosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 404)
# Related Disease Score Top Affiliating Genes
1 familial avascular necrosis of the femoral head 32.2 TRPV4 COL2A1
2 arthropathy 30.4 TRPV4 COL2A1
3 bone disease 30.3 GBA1 COL2A1
4 clubfoot 29.7 TRPV4 COL2A1
5 osteochondrodysplasia 29.2 TRPV4 COL2A1
6 avascular necrosis of femoral head, primary, 1 11.9
7 osteonecrosis 11.7
8 legg-calve-perthes disease 11.7
9 avascular necrosis of femoral head, primary, 2 11.5
10 dieterich's disease 11.5
11 osteochondrosis of the metatarsal bone 11.5
12 kohler's disease 11.5
13 idiopathic avascular necrosis 11.3
14 traumatic avascular necrosis 11.3
15 kienbock's disease 11.2
16 secondary avascular necrosis 11.2
17 primary avascular necrosis 11.2
18 avascular necrosis of genetic origin 11.2
19 secondary non-traumatic avascular necrosis 11.2
20 rare hereditary disease with avascular necrosis 11.2
21 dyskeratosis congenita 11.1
22 thiemann disease 11.1
23 arthrogryposis, perthes disease, and upward gaze palsy 11.1
24 dysbaric osteonecrosis 11.1
25 freiberg's disease 11.1
26 pr interval, variation in 11.0
27 sickle cell anemia 10.8
28 sickle cell disease 10.8
29 developmental dysplasia of the hip 1 10.7
30 osteoarthritis 10.7
31 epiphysiolysis of the hip 10.7
32 systemic lupus erythematosus 10.7
33 systemic lupus erythematosus 1 10.7
34 lupus erythematosus 10.7
35 alcohol use disorder 10.6
36 alcohol dependence 10.5
37 leukemia, acute lymphoblastic 10.5
38 graft-versus-host disease 10.5
39 conn's syndrome 10.4
40 gaucher's disease 10.4
41 deficiency anemia 10.4
42 osteochondrosis 10.4
43 thoracoabdominal syndrome 10.4
44 thalassemia 10.4
45 bunion 10.4
46 bone mineral density quantitative trait locus 15 10.4
47 antiphospholipid syndrome 10.4
48 septic arthritis 10.4
49 vasculitis 10.4
50 myeloid leukemia 10.4

Graphical network of the top 20 diseases related to Avascular Necrosis:

Diseases related to Avascular Necrosis

Symptoms & Phenotypes for Avascular Necrosis

MGI Mouse Phenotypes related to Avascular Necrosis:

# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.26 COL2A1 GBA1 NEK9 TRPV4
2 respiratory system MP:0005388 8.8 COL2A1 GBA1 TRPV4

Drugs & Therapeutics for Avascular Necrosis

Drugs for Avascular Necrosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 105)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Tacrine Approved, Investigational, Withdrawn Phase 4 321-64-2 1935
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
Meloxicam Approved, Vet_approved Phase 4 71125-38-7 54677470 5281106
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
Vecuronium Approved, Investigational Phase 4 50700-72-6, 86029-43-8 39765 39764
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
Desflurane Approved Phase 4 57041-67-5 42113
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
13 Anesthetics Phase 4
14 Anti-Inflammatory Agents Phase 4
15 Platelet Aggregation Inhibitors Phase 4
16 Nootropic Agents Phase 4
17 Cholinesterase Inhibitors Phase 4
18 Cholinergic Agents Phase 4
19 Antirheumatic Agents Phase 4
20 Bromides Phase 4
21 Antipyretics Phase 4
22 Neuromuscular Nondepolarizing Agents Phase 4
23 Neuromuscular Blocking Agents Phase 4
24 Anti-Arrhythmia Agents Phase 4
25 Anti-Anxiety Agents Phase 4
Ketorolac Tromethamine Phase 4
27 Cyclooxygenase Inhibitors Phase 4
28 Excitatory Amino Acid Antagonists Phase 4
29 Psychotropic Drugs Phase 4
30 Cyclooxygenase 2 Inhibitors Phase 4
31 Anesthetics, Local Phase 4
32 Anti-Inflammatory Agents, Non-Steroidal Phase 4
33 Anesthetics, Intravenous Phase 4
34 Anesthetics, Inhalation Phase 4
35 Anesthetics, General Phase 4
36 Hypnotics and Sedatives Phase 4
37 Analgesics, Non-Narcotic Phase 4
38 Analgesics Phase 4
39 Cholinergic Antagonists Phase 4
40 Sodium Chloride Symporter Inhibitors Phase 4
41 diuretics Phase 4
42 Gentamicins Phase 4
43 Vasodilator Agents Phase 4
44 Protective Agents Phase 4
45 Polymethyl Methacrylate Phase 4
Zoledronic acid Approved Phase 3 118072-93-8 68740
Tocopherol Approved, Investigational Phase 3 1406-66-2
Pentoxifylline Approved, Investigational Phase 3 6493-05-6 4740
Cholecalciferol Approved, Nutraceutical, Vet_approved Phase 3 67-97-0, 1406-16-2 5280795 10883523
DL-alpha-Tocopherol Approved, Experimental, Investigational, Nutraceutical, Vet_approved Phase 3 59-02-9, 10191-41-0 2116 14985

Interventional clinical trials:

(show top 50) (show all 190)
# Name Status NCT ID Phase Drugs
1 The 3DKnee™ System: A Post-Market Study Completed NCT00764673 Phase 4
2 Is Ceramic-on-Ceramic THA Superior to Ceramic-on-Highly Cross-Linked Polyethylene THA in Patients Less Than 55 Years Old? Completed NCT03639532 Phase 4
3 Opioid-Free Shoulder Arthroplasty Completed NCT03540030 Phase 4 Gabapentin;Celecoxib;toradol;acetaminophen;regional block;propofol;IV lidocaine;rocuronium;vecuronium;sevoflurane;desflurane
4 A Prospective, Randomised, Controlled, Single Centre, Blinded Study of the Wear Characteristics of Two Polyethylene Bearing Surfaces, Enduron vs. Marathon Completed NCT00208442 Phase 4
5 A Prospective, Randomised, Uncontrolled, Single-Centre, Post-Market Surveillance Study To Evaluate The Performance Of SmartSet® HV and SmartSet® GHV Bone Cements In Primary Cemented Total Hip Arthroplasty(THA) Completed NCT00872066 Phase 4
6 Multicenter Post Approval Study of the Trilogy AB(R) Acetabular System Terminated NCT00715026 Phase 4
7 DURALOC® Option Ceramic-on-Ceramic Hip Prosthesis System PMA Post-approval Study Terminated NCT00546598 Phase 4
8 A Multi-centre, Prospective, Uncontrolled Post Market Clinical Follow-up Study (PMCFS) to Monitor the Survival and Performance of the DeltaMotion Cup System in Subjects Requiring a Total Hip Replacement Terminated NCT01635166 Phase 4
9 Uncontrolled Prospective Multi-Centre Post Marketing Surveillance Study to Monitor the Long Term Survivorship of Pinnacle™ Acetabular Cup Prosthesis With a Ceramic-on-ceramic Bearing in Subjects With Aetiologies Requiring a Primary Total Hip Replacement Terminated NCT00872222 Phase 4
10 Randomised, Controlled, Prospective, Multi-Centre, Post Market Surveillance Study Comparing a Ceramic-on-Metal Bearing and a Metal-on-Metal Bearing in Subjects Requiring Primary Total Hip Arthroplasty for Non-Inflammatory Degenerative Joint Disease Terminated NCT00873444 Phase 4
11 Randomised, Prospective, RSA, PMS Study Comparing Acryloc™ & Palacos R in Primary Total Hip Arthroplasty Terminated NCT00208403 Phase 4
12 Prospective, Uncontrolled, Multi-Centre, Post-Marketing Surveillance Study to Evaluate the Long-Term Performance of Summit Tapered Hip in Cementless Total Hip Arthroplasty Terminated NCT00208390 Phase 4
13 Prospective Multi-Centre, Uncontrolled, Post Marketing Surveillance Study to Monitor the Long-Term Performance of the DePuy ASR Hip System in Subjects With Suitable Indications for a Primary Resurfacing Hip Arthroplasty Terminated NCT00208377 Phase 4
14 Uncontrolled Prospective Multi-Centre Post Marketing Surveillance Study to Monitor the Long Term Survivorship of Pinnacle Acetabular Cup Prosthesis With a Metal on Metal Bearing in Subjects With Aetiologies Requiring a Primary Total Hip Replacement Terminated NCT00208364 Phase 4
15 An Uncontrolled, Multi-Centre, Prospective, Post Marketing Surveillance Study to Monitor the Long Term Survivorship of the DePuy PROXIMA™ Hip in Subjects Requiring a Total Hip Replacement Terminated NCT00208455 Phase 4
16 Prospective Single-centre, Uncontrolled, Post Marketing Surveillance Study to Monitor the Long-term Performance of the DePuy ASR™ Hip in Subjects With Suitable Indications for a Primary Resurfacing Hip Arthroplasty Terminated NCT00872794 Phase 4
17 Prospective, International Multi-centre, Uncontrolled, Post Marketing Surveillance Study to Monitor the Long-term Performance of a Large Metal-on-Metal (MoM) Bearing Comprising a DePuy ASR™ Cup in Conjunction With Either a DePuy ASR™ Hip Resurfacing Femoral Component or a DePuy ASR™ XL Head in Subjects With Indications Suitable for Either a Primary Resurfacing Arthroplasty or Primary Total Hip Arthroplasty Terminated NCT00872547 Phase 4
18 Prospective, Uncontrolled, Two-centre, RSA, Post-market Surveillance Study to Evaluate the Stability of the C-Stem™ AMT Femoral Component in Primary Total Hip Arthroplasty. Terminated NCT00872573 Phase 4
19 Prospective, International Multi-centre, Uncontrolled, Post Marketing Surveillance Study to Monitor the Long-term Performance of the DePuy PROXIMA™ Hip in Subjects With Indications Suitable for a Primary Total Hip Arthroplasty Terminated NCT01134445 Phase 4
20 A Randomized Multicentre Clinical Trial Comparing The Metal on Metal Hip System Versus The Metal on Highly Crossed Linked Polyethylene System Terminated NCT01422564 Phase 4
21 Uncontrolled Prospective Multi-Centre Post Marketing Surveillance Study to Monitor the Long Term Survivorship of Pinnacle Acetabular Cup System With a Metal on Enduron Polyethylene Bearing in Subjects With Aetiologies Requiring a Primary Total Hip Replacement Withdrawn NCT00208429 Phase 4
22 Control Study of Implantation of Enriched Bone Marrow Cells for the Treatment of Avascular Necrosis of Femoral Head Unknown status NCT01613612 Phase 2, Phase 3
23 Encore Mobile - Bearing Knee Study #200 Completed NCT00765362 Phase 3
24 Multicenter, Open-labeled, Randomized Clinical Trial to Determine the Efficacy of Zoledronic Acid in Preventing Collapse of the Osteonecrotic Femoral Head Completed NCT00939900 Phase 3 zoledronic acid (aclasta)
25 Pentoxifylline and Tocopherol (PENTO) in the Treatment of Medication-related Osteonecrosis of the Jaw (MRONJ): A Prospective, Randomized Controlled Trial to Evaluate a Novel Non-operative Treatment Enrolling by invitation NCT03040778 Phase 3 Pentoxifylline;Placebo;Tocopherol
26 Clinical and Radiographic Evaluation to Compare a Polished and Non-polished Collared Stem and a Polished and Non Polished Collarless Stem in Primary Total Hip Replacement Terminated NCT00208351 Phase 3
27 A Multi-centre, Randomised, Parallel Group, Controlled Study to Compare the Performance of the Future Hip Against Three Currently Used Implants in Total Hip Replacement Terminated NCT00208468 Phase 3
28 Treatment for Hip, Knee, Ankle and Shoulder Osteonecrosis With Autologous Mononuclear Cells Transplantation in People With Sickle Cell Disease Unknown status NCT02448121 Phase 1, Phase 2
29 Evaluation of Safety and Feasibility of Bone Marrow Derived Autologous MSCs to Enhance Bone Healing in Patients With Avascular Necrosis of the Femoral Head Completed NCT02065167 Phase 2
30 A Pilot Clinical Trial of "ex Vivo" Expanded Autologous Bone Marrow Mesenchymal Stem Cells Fixed in Allogenic Human Bone Tissue (XCEL-MT-OSTEO- ALPHA) in Osteonecrosis of the Femoral Head Completed NCT01605383 Phase 1, Phase 2
31 Treatment of Osteonecrosis of the Femoral Head by Implantation of Preosteoblastic Cells: a Randomized, Controlled, Single Blind Pilot Study Completed NCT02890537 Phase 2 Core decompression/PREOB® implantation;Core decompression/BMC implantation
32 AVN Prevention With Lipitor in Lupus Erythematosus APLLE Trial Terminated NCT00412841 Phase 2 Atorvastatin;Placebo
33 Effects of Lacosamide on Post-operative Opioid Requirements After a Total Hip Arthroplasty: A Randomized Double -Blinded, Placebo-controlled Pilot Study. Withdrawn NCT02342977 Phase 2 Placebo;Lacosamide
34 Autologous Bone Marrow Derived Mesenchymal Stromal Cells Transplantation for Human Avascular Necrosis of the Lunate Bone of the Wrist (Kienbock's Disease) Unknown status NCT02646007 Phase 1
35 Comparison of Acetabular Shell Position Using Patient Specific Instruments vs. Standard Surgical Instruments: A Randomized Clinical Trial Completed NCT01791738 Phase 1
36 The Effect of Autologous Bone Marrow Concentration Combined With Core Decompression for Avascular Necrosis of Femoral Head Unknown status NCT03787329
37 Talar Avascular Necrosis: Surgical Angiogenesis Compared to Core Decompression With Osseous Autografting Unknown status NCT02289976
38 Talar Avascular Necrosis: Surgical Angiogenesis Compared to Core Decompression With Osseous Auto Grafting Unknown status NCT02291900
39 Molecular Genetic Study of Avascular Necrosis of the Femoral Head-Revealing ANFH Pathogenesis Mechanism by Cell and Animal Models Unknown status NCT00260897
40 Porous Tantalum Rods Improve the Hip Joint Function of Patients With Avascular Necrosis of the Femoral Head After Femoral Neck Fracture Surgery: a Randomized Controlled Trial Unknown status NCT02877472
41 Phase 3 Randomized Controlled Study to Demonstrate Safety and Effectiveness of the BIOLOX Delta CoC THR System Unknown status NCT01921309
42 The Verification Study on the Early Fixation/ Stability of Tritanium Cup Unknown status NCT02552069
43 A Prospective Cohort Study to Document the Clinical Outcomes in Shoulder Hemi-arthroplasty Using a PyC Spherical Interpositional Implant Unknown status NCT02424760
44 Femoral Head Resurfacing Versus a Large Femoral Head (Durom®) Total Hip System: A Prospective Randomized Trial Unknown status NCT00175487
45 An Observational Cohort Study Evaluating the Safety and Performance of Aequalis Resurfacing Head Implant in a Consecutive Series of Patients With Shoulder Arthroplasty Unknown status NCT02444299
46 Total Hip Replacement - MP-1 Acetabular Liner Unknown status NCT02503891
47 Core Decompression With Bone Chips Allograft Adjuvanted by Fibrin Platelet Rich-plasma (PRP) and Concentrated Autologous Mesenchymal Stromal Cells (MSCS): Results in Avascular Necrosis of Femoral Head (AVN) After 2 Years Minimum Follow-up Completed NCT04210440
48 Hyperbaric Oxygen Therapy Versus Core Decompression Augmented With Bone Substitute in Pre Collapse of Avascular Necrosis of Femoral Head Completed NCT04657653
49 Avascular Necrosis of Weight-Bearing Joints In Patients With Hematologic Malignancies Treated With Dexamethasone Or Prednisone Completed NCT00719147
50 Randomized Study of Decompression Coring Versus Conservative Therapy in Patients With Avascular Necrosis of the Hip Related to Sickle Cell Disease Completed NCT00006130

Search NIH Clinical Center for Avascular Necrosis

Genetic Tests for Avascular Necrosis

Genetic tests related to Avascular Necrosis:

# Genetic test Affiliating Genes
1 Avascular Necrosis 28

Anatomical Context for Avascular Necrosis

Organs/tissues related to Avascular Necrosis:

MalaCards : Bone, Bone Marrow, Endothelial, Liver, Kidney, Dorsal Root Ganglion, Myeloid

Publications for Avascular Necrosis

Articles related to Avascular Necrosis:

(show top 50) (show all 7224)
# Title Authors PMID Year
Timing of initiation of enzyme replacement therapy after diagnosis of type 1 Gaucher disease: effect on incidence of avascular necrosis. 53 62
19732054 2009
Imiglucerase (Cerezyme) improves quality of life in patients with skeletal manifestations of Gaucher disease. 53 62
17539908 2007
Long-term bone outcomes in Italian patients with Gaucher disease type 1 or type 3 treated with imiglucerase: A sub-study from the International Collaborative Gaucher Group (ICGG) Gaucher Registry. 62
36327675 2023
Augmenting Pathologic Acetabular Bone Loss With Photodynamic Nails to Support Primary Total Hip Arthroplasty. 62
36267396 2022
COVID -19 Precipitating Vaso-Occlusive Crisis in a Patient of Sickle Cell Anemia with Avascular Necrosis of Femur. 62
35057606 2022
Short-term clinical outcomes of minimally invasive porous bioceramic rod in treatment of avascular necrosis of the femoral head. 62
36462981 2022
Debilitating hip degeneration in trichothiodystrophy: Association with ERCC2/XPD mutations, osteosclerosis, osteopenia, coxa valga, contractures, and osteonecrosis. 62
36103153 2022
Osteoarticular manifestation of acute lymphoblastic leukemia in adults: a literature review. 62
36454343 2022
Complications of Corticosteroid Therapy: A Comprehensive Literature Review. 62
36311302 2022
Ex vivo Study of Detergent-Assisted Intraosseous Bone Wash Treatment of Osteonecrosis. 62
36453529 2022
Skeletal Outcomes in Children and Young Adults with Glomerular Disease. 62
36171052 2022
Prediction of total healthcare cost following total shoulder arthroplasty utilizing machine learning. 62
36007864 2022
Outcome measures and survivorship following total hip arthroplasty in adolescent population. 62
35945465 2022
First Metatarsophalangeal Arthrodesis for the Failed Hallux. 62
36368794 2022
Presence and magnitude of anterior physeal separation in slipped upper femoral epiphysis helps identifying those at high risk for avascular necrosis. 62
36307269 2022
Mesenchymal stem cells for subchondral bone marrow lesions: From bench to bedside. 62
36310763 2022
First clinical results of 1-year follow-up of the femoral neck system for internal fixation of femoral neck fractures. 62
34734328 2022
Treatment of elderly comminuted proximal humeral fracture using endosteal anatomical support system: A case report. 62
36473269 2022
Good functional results with open reduction and internal fixation for locked posterior shoulder fracture-dislocation: a case series. 62
35971599 2022
Comparing Propofol With Fentanyl and Midazolam for Sedation in Closed Reductions of Traumatic Hip Dislocations. 62
36343635 2022
Editorial Commentary: Routine Preoperative Magnetic Resonance Imaging for Hip Arthroscopy Is Wasting Health Care Dollars and Delaying Surgical Intervention: Decision Making Should Be at the Discretion of the Health Care Provider Not Mandated by Health Care Insurers. 62
36344059 2022
The morphologic and morphometric features of the triquetrum. 62
36400416 2022
Clinical and radiological outcomes of internal fixation of complex talar neck and body fractures with locking plates through a dual approach. 62
35850424 2022
Conversion Hip Arthroplasty Using Standard and Long Stems after Failed Internal Fixation of Intertrochanteric Fractures. 62
36394199 2022
The fate of acetabular fracture fixation at 10 years: rates of conversion to arthroplasty. 62
36396614 2022
Utilization of the Pedicled and Free Fibula Flap for Ankle Arthrodesis. 62
36438462 2022
"In-Out-In" Percutaneous Reduction Technique for Treatment of Valgus-Impacted Femoral Neck Fractures: A Technical Trick and Case Series. 62
36419316 2022
Reverse Total Shoulder Arthroplasty Demonstrates Better Outcomes Than Angular Stable Plate in the Treatment of Three-part and Four-part Proximal Humerus Fractures in Patients Older Than 70 Years. 62
36383078 2022
Diagnosis and Treatment of Avascular Necrosis of the Humeral Head: Current Concepts. 62
36435432 2022
Clinical and radiological outcome of Mason-Johnston types III and IV radial head fractures treated by an on-table reconstruction. 62
36403016 2022
Rescue technique for trapped bone needle in cement cast. 62
35046085 2022
Relative frequency of primary total hip arthroplasty for avascular necrosis in the United States as compared to a regional center: A data review. 62
36204516 2022
Avascular Necrosis of the Carpal Bones: Etiologies and Treatments. 62
36244716 2022
Avascular Necrosis of Capitate and Other Uncommon Presentations of Carpal Avascular Necrosis. 62
36244715 2022
Avascular Necrosis and Time to Surgery for Unstable Slipped Capital Femoral Epiphysis: A Systematic Review and Meta-analysis. 62
35941089 2022
A systematic review on the management of idiopathic avascular necrosis of the scaphoid (Preiser's disease). 62
36410658 2022
Post-traumatic avascular necrosis of tibial plafond following an ankle fracture. 62
32146071 2022
Preiser's Disease-Current Concepts of Etiology and Management. 62
36244714 2022
Does a fibula-sparing approach improve outcomes in tibiotalocalcaneal arthrodesis? 62
36424297 2022
Pathophysiology of Avascular Necrosis. 62
36244704 2022
Clinical and Radiographic Outcomes of Percutaneous Third-Generation Double First Metatarsal Osteotomy Combined With Closing-Wedge Proximal Phalangeal Osteotomy for Moderate and Severe Hallux Valgus. 62
36036667 2022
Proximal humeral fractures treated with a low-profile plate with enhanced fixation properties. 62
34625328 2022
Modified Dunn procedure versus percutaneous pinning in moderate/severe stable slipped capital femoral epiphyses. 62
33829904 2022
Total Hip Arthroplasty via direct anterior approach for osteonecrosis; comparison with primary hip osteoarthritis in a mid term follow up. 62
36263249 2022
Motorized Plate Lengthening of the Femur in Children: A Preliminary Report. 62
36084628 2022
Physical disability in Late Antiquity Milan: slipped capital femoral epiphysis with severe secondary joint disease in the Basilica of San Dionigi. 62
36218258 2022
Long-term opioid therapy among patients with systemic lupus erythematosus in the community. A Lupus Midwest Network study. 62
36379579 2022
Comorbidities among Egyptian systemic lupus erythematosus: The COMOSLE-EGYPT study. 62
36373605 2022
Are outcomes after fixation of distal humerus coronal shear fractures affected by surgical approach? A systematic review and meta-analysis. 62
36353417 2022
Sickle cell bone disease and response to intravenous bisphosphonates in children. 62
35904681 2022

Variations for Avascular Necrosis

Expression for Avascular Necrosis

Search GEO for disease gene expression data for Avascular Necrosis.

Pathways for Avascular Necrosis

GO Terms for Avascular Necrosis

Biological processes related to Avascular Necrosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 central nervous system development GO:0007417 9.13 GBA1 COL2A1
2 cartilage development involved in endochondral bone morphogenesis GO:0060351 8.92 TRPV4 COL2A1

Sources for Avascular Necrosis

8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
27 GO
28 GTR
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
36 LifeMap
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
70 Tocris
72 UMLS via Orphanet
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