MCID: AVD001
MIFTS: 37

Avoidant Personality Disorder

Categories: Mental diseases

Aliases & Classifications for Avoidant Personality Disorder

MalaCards integrated aliases for Avoidant Personality Disorder:

Name: Avoidant Personality Disorder 12 77 15 74
Anxious Personality Disorder 12 74
Personality Disorders 45 74

Classifications:



External Ids:

Disease Ontology 12 DOID:1509
ICD9CM 36 301.82
MeSH 45 D010554
NCIt 51 C92636
SNOMED-CT 69 37746008
ICD10 34 F60.6

Summaries for Avoidant Personality Disorder

Disease Ontology : 12 A personality disorder that is characterized by a pervasive pattern of social inhibition, feelings of inadequacy, extreme sensitivity to negative evaluation, and avoidance of social interaction.

MalaCards based summary : Avoidant Personality Disorder, also known as anxious personality disorder, is related to antisocial personality disorder and conduct disorder, and has symptoms including photophobia, restlessness and personality changes. An important gene associated with Avoidant Personality Disorder is MAOA (Monoamine Oxidase A), and among its related pathways/superpathways are Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways and Amino Acid metabolism. The drugs Benzocaine and tannic acid have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and amygdala.

Wikipedia : 77 Avoidant personality disorder (AvPD) is a Cluster C personality disorder. Those affected display a... more...

Related Diseases for Avoidant Personality Disorder

Diseases related to Avoidant Personality Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 186)
# Related Disease Score Top Affiliating Genes
1 antisocial personality disorder 33.9 MAOA SLC6A4
2 conduct disorder 31.1 MAOA SLC6A4 TPH1
3 personality disorder 30.7 MAOA SLC6A4 TPH1
4 social phobia 30.7 MAOA SLC6A4
5 dysthymic disorder 30.2 MAOA SLC6A4
6 panic disorder 30.2 MAOA SLC6A4
7 agoraphobia 30.1 MAOA SLC6A4
8 anxiety 30.1 MAOA SLC6A4 TPH1
9 major depressive disorder 30.1 MAOA SLC6A4 TPH1
10 attention deficit-hyperactivity disorder 30.0 MAOA SLC6A4 TPH1
11 pathological gambling 30.0 MAOA SLC6A4
12 mood disorder 30.0 MAOA SLC6A4 TPH1
13 substance dependence 29.9 MAOA SLC6A4
14 post-traumatic stress disorder 29.8 MAOA SLC6A4
15 mental depression 29.8 MAOA SLC6A4 TPH1
16 alcohol dependence 29.8 MAOA SLC6A4 TPH1
17 chronic fatigue syndrome 29.7 MAOA SLC6A4
18 depression 29.6 MAOA SLC6A4 TPH1
19 atypical depressive disorder 29.6 MAOA SLC6A4
20 postpartum depression 29.5 MAOA SLC6A4
21 kleptomania 29.5 MAOA SLC6A4
22 substance abuse 29.4 MAOA SLC6A4
23 generalized anxiety disorder 29.4 MAOA SLC6A4 TPH1
24 paranoid schizophrenia 29.4 MAOA SLC6A4
25 borderline personality disorder 29.4 MAOA SLC6A4 TPH1
26 disease of mental health 29.4 MAOA SLC6A4
27 schizophrenia 29.3 MAOA SLC6A4 TPH1
28 opiate dependence 29.3 SLC6A4 TPH1
29 oppositional defiant disorder 29.2 MAOA SLC6A4
30 endogenous depression 29.2 MAOA SLC6A4 TPH1
31 psychotic disorder 29.2 SLC6A4 TPH1
32 obsessive-compulsive disorder 29.2 MAOA SLC6A4 TPH1
33 tobacco addiction 29.1 MAOA SLC6A4 TPH1
34 migraine with or without aura 1 29.0 MAOA SLC6A4 TPH1
35 dependent personality disorder 12.7
36 histrionic personality disorder 12.6
37 paranoid personality disorder 12.6
38 schizoid personality disorder 12.6
39 schizotypal personality disorder 12.6
40 narcissistic personality disorder 12.6
41 multiple personality disorder 12.5
42 cyclothymic disorder 11.4
43 dissociative seizures 10.9
44 impulse control disorder 10.7
45 dystonia 11, myoclonic 10.6
46 digeorge syndrome 10.6
47 ceroid lipofuscinosis, neuronal, 8 10.6
48 ceroid lipofuscinosis, neuronal, 7 10.6
49 gardner-diamond syndrome 10.6
50 bipolar disorder 10.5

Comorbidity relations with Avoidant Personality Disorder via Phenotypic Disease Network (PDN):


Dependent Personality Disorder Dysthymic Disorder
Major Depressive Disorder

Graphical network of the top 20 diseases related to Avoidant Personality Disorder:



Diseases related to Avoidant Personality Disorder

Symptoms & Phenotypes for Avoidant Personality Disorder

UMLS symptoms related to Avoidant Personality Disorder:


photophobia, restlessness, personality changes, pseudobulbar behavioral symptoms, sleep disturbances

Drugs & Therapeutics for Avoidant Personality Disorder

Drugs for Avoidant Personality Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Benzocaine Approved, Investigational Not Applicable 94-09-7, 1994-09-7 2337
2
tannic acid Approved Not Applicable 1401-55-4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effectiveness of Group Based Schema Therapy in the Treatment of Personality Disorders Completed NCT00247234 Not Applicable
2 Changes in the Brain as Borderline Patients Learn to Regulate Their Emotions Completed NCT02465697 Not Applicable
3 Effectiveness of PTSD-treatment Compared to Integrated PTSD-PD-treatment in Adult Patients With Comorbid PTSD and CPD Recruiting NCT03833531 Not Applicable
4 FCT Study: Reducing the Need for Out-of-Home Placements Recruiting NCT03641664 Not Applicable

Search NIH Clinical Center for Avoidant Personality Disorder

Cochrane evidence based reviews: personality disorders

Genetic Tests for Avoidant Personality Disorder

Anatomical Context for Avoidant Personality Disorder

MalaCards organs/tissues related to Avoidant Personality Disorder:

42
Brain, Testes, Amygdala

Publications for Avoidant Personality Disorder

Articles related to Avoidant Personality Disorder:

(show top 50) (show all 102)
# Title Authors Year
1
Social anxiety disorder and avoidant personality disorder from an interpersonal perspective. ( 30656823 )
2019
2
Struggling to be a person: Lived experience of avoidant personality disorder. ( 30609024 )
2019
3
Treating comorbid depression and avoidant personality disorder: The case of Andy. ( 30779449 )
2019
4
Relationships Among Avoidant Personality Disorder, Social Anxiety Disorder, and Normative Personality Traits: A Twin Study. ( 29505386 )
2018
5
Avoidant personality disorder: current insights. ( 29563846 )
2018
6
Avoidant personality disorder and social phobia: Does mindreading make the difference? ( 29096207 )
2018
7
The fear of being laughed at as additional diagnostic criterion in social anxiety disorder and avoidant personality disorder? ( 29176893 )
2017
8
Examination of DSM-5 Section III avoidant personality disorder in a community sample. ( 28703479 )
2017
9
Brain structural anomalies in borderline and avoidant personality disorder patients and their associations with disorder-specific symptoms. ( 27155069 )
2016
10
Avoidant personality disorder as a social anxiety phenotype: risk factors, associations and treatment. ( 26651009 )
2016
11
Avoidant Personality Disorder: a Current Review. ( 26830887 )
2016
12
Group schema therapy versus group cognitive behavioral therapy for social anxiety disorder with comorbid avoidant personality disorder: study protocol for a randomized controlled trial. ( 27717405 )
2016
13
A personality and impairment approach to examine the similarities and differences between avoidant personality disorder and social anxiety disorder. ( 27653504 )
2016
14
Mindreading Dysfunction in Avoidant Personality Disorder Compared With Other Personality Disorders. ( 27227557 )
2016
15
Affective Instability as a Clinical Feature of Avoidant Personality Disorder. ( 27505187 )
2016
16
Sex determines cortisol and alpha-amylase responses to acute physical and psychosocial stress in patients with avoidant personality disorder. ( 27547506 )
2016
17
The Talking Cure of Avoidant Personality Disorder: Remission through Earned-Secure Attachment. ( 27662043 )
2016
18
Paroxetine, Cognitive Therapy or Their Combination in the Treatment of Social Anxiety Disorder with and without Avoidant Personality Disorder: A Randomized Clinical Trial. ( 27744447 )
2016
19
Metacognitive interpersonal therapy for co-occurrent avoidant personality disorder and substance abuse. ( 25557644 )
2015
20
Serum concentrations of chemokines (CCL-5 and CXCL-12), chemokine receptors (CCR-5 and CXCR-4), and IL-6 in patients with posttraumatic stress disorder and avoidant personality disorder. ( 26481549 )
2015
21
Longitudinal Associations Between Social Anxiety Disorder and Avoidant Personality Disorder: A Twin Study. ( 26569037 )
2015
22
Correction: Avoidant Personality Disorder versus Social Phobia: The Significance of Childhood Neglect. ( 25978045 )
2015
23
Attachment styles in patients with avoidant personality disorder compared with social phobia. ( 26332087 )
2015
24
Social anxiety disorders in clinical practice: differentiating social phobia from avoidant personality disorder. ( 26129819 )
2015
25
Avoidant Personality Disorder versus Social Phobia: The Significance of Childhood Neglect. ( 25815817 )
2015
26
The neural correlates of anomalous habituation to negative emotional pictures in borderline and avoidant personality disorder patients. ( 24275960 )
2014
27
Doing Psychiatry Right: A Case of Severe Avoidant Personality Disorder with Obsessive-compulsive Personality Disorder, Obsessive Compulsive Disorder, Intermittent Explosive Disorder and Sexual Paraphilias. ( 25035563 )
2014
28
Elevated amygdala activity during reappraisal anticipation predicts anxiety in avoidant personality disorder. ( 25451388 )
2014
29
Population-based, multi-generational family clustering study of social anxiety disorder and avoidant personality disorder. ( 25215596 )
2014
30
Social Phobia and Avoidant Personality Disorder: Similar but Different? ( 23398095 )
2013
31
Multimodal examination of emotion regulation difficulties as a function of co-occurring avoidant personality disorder among women with borderline personality disorder. ( 24378158 )
2013
32
Personality functioning in patients with avoidant personality disorder and social phobia. ( 23786266 )
2013
33
A parallel process growth model of avoidant personality disorder symptoms and personality traits. ( 22506627 )
2013
34
Self-esteem and other-esteem in college students with borderline and avoidant personality disorder features: An experimental vignette study. ( 24343980 )
2013
35
Brief Cognitive Therapy for Avoidant Personality Disorder. ( 24377411 )
2013
36
Avoidant personality disorder in individuals with generalized social anxiety disorder: what does it add? ( 22705954 )
2012
37
Speed and accuracy of facial expression classification in avoidant personality disorder: a preliminary study. ( 22448805 )
2011
38
The effect of Avoidant Personality Disorder on the persistence of Generalized Social Anxiety Disorder in the general population: results from a longitudinal, nationally representative mental health survey. ( 21308885 )
2011
39
Psychotherapy of an older adult with an avoidant personality disorder. ( 20880430 )
2011
40
Changes in defensive functioning in a case of avoidant personality disorder. ( 22402007 )
2010
41
Does avoidant personality disorder impact on the outcome of treatment for bulimia nervosa? ( 19536877 )
2010
42
Relations among symptoms of social phobia subtypes, avoidant personality disorder, panic, and depression. ( 20171323 )
2010
43
Co-occurrence of avoidant personality disorder and child sexual abuse predicts poor outcome in long-standing eating disorder. ( 20677852 )
2010
44
Avoidant personality disorder symptoms in first-degree relatives of schizophrenia patients predict performance on neurocognitive measures: the UCLA family study. ( 20053537 )
2010
45
Avoidant personality disorder and its relationship to social phobia. ( 19187715 )
2009
46
The relationship between generalized social phobia and avoidant personality disorder in a national mental health survey. ( 19031488 )
2009
47
Predictors of withdrawal: possible precursors of avoidant personality disorder. ( 19583885 )
2009
48
Factor structure and diagnostic efficiency of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, criteria for avoidant personality disorder in Hispanic men and women with substance use disorders. ( 19683617 )
2009
49
Social phobia and avoidant personality disorder: are they separate diagnostic entities or do they reflect a spectrum of social anxiety? ( 19728570 )
2009
50
The impact of avoidant personality disorder on psychosocial impairment is substantial. ( 19333817 )
2009

Variations for Avoidant Personality Disorder

Expression for Avoidant Personality Disorder

Search GEO for disease gene expression data for Avoidant Personality Disorder.

Pathways for Avoidant Personality Disorder

GO Terms for Avoidant Personality Disorder

Biological processes related to Avoidant Personality Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 circadian rhythm GO:0007623 8.62 SLC6A4 TPH1

Sources for Avoidant Personality Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....