B-Cell Adult Acute Lymphocytic Leukemia

Categories: Blood diseases, Cancer diseases, Immune diseases

Aliases & Classifications for B-Cell Adult Acute Lymphocytic Leukemia

MalaCards integrated aliases for B-Cell Adult Acute Lymphocytic Leukemia:

Name: B-Cell Adult Acute Lymphocytic Leukemia 12 15
Adult B Acute Lymphoblastic Leukemia 12 17
Adult B-Cell Acute Lymphoblastic Leukaemia 12
Adult B-Cell Acute Lymphoblastic Leukemia 12
B-Cell Adult Acute Lymphoblastic Leukemia 71
B-Cell Adult Acute Lymphocytic Leukaemia 12
Adult B Acute Lymphoblastic Leukaemia 12
Adult B-Cell Lymphocytic Leukaemia 12
Adult B-Cell Lymphocytic Leukemia 12
Adult B-Lymphoblastic Leukaemia 12
Adult B-Lymphoblastic Leukemia 12


External Ids:

Disease Ontology 12 DOID:0060592
NCIt 49 C9143
UMLS 71 C0279593

Summaries for B-Cell Adult Acute Lymphocytic Leukemia

Disease Ontology : 12 An adult acute ymphoblastic leukemia occurring in adults and that has mateiral basis in B lymphocytes.

MalaCards based summary : B-Cell Adult Acute Lymphocytic Leukemia, also known as adult b acute lymphoblastic leukemia, is related to precursor t-cell acute lymphoblastic leukemia and acute leukemia, and has symptoms including bone pain An important gene associated with B-Cell Adult Acute Lymphocytic Leukemia is IKZF1 (IKAROS Family Zinc Finger 1). The drugs Methylprednisolone and Prednisolone phosphate have been mentioned in the context of this disorder. Affiliated tissues include b cells, b lymphoblasts and t cells, and related phenotypes are hematopoietic system and immune system

Related Diseases for B-Cell Adult Acute Lymphocytic Leukemia

Diseases in the B-Cell Adult Acute Lymphocytic Leukemia family:

T-Cell Adult Acute Lymphocytic Leukemia

Diseases related to B-Cell Adult Acute Lymphocytic Leukemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 39)
# Related Disease Score Top Affiliating Genes
1 precursor t-cell acute lymphoblastic leukemia 29.4 IKZF1 BCR ANPEP ABL1
2 acute leukemia 29.0 ZNF384 BCR ANPEP
3 adult acute lymphocytic leukemia 28.9 PBX1 IKZF1 CD19 ANPEP ABL1
4 leukemia, acute lymphoblastic 28.3 PBX1 IKZF1 CD19 BCR ANPEP ABL1
5 leukemia, acute lymphoblastic 3 28.3 PBX1 IKZF1 CD19 BCR ANPEP ABL1
6 leukemia, acute myeloid 27.4 PBX1 IKZF1 EVPL CD19 BCR ANPEP
7 b-lymphoblastic leukemia/lymphoma, bcr-abl1-like 10.3 IKZF1 ABL1
8 mental retardation, autosomal dominant 33 10.2 IKZF1 ABL1
9 pineal region germinoma 10.2 ZNF384 MSI2
10 leukemia, chronic lymphocytic 10.1
11 myeloma, multiple 10.1
12 myelodysplastic syndrome 10.1
13 graft-versus-host disease 10.1
14 mucositis 10.1
15 neutropenia 10.1
16 t-cell acute lymphoblastic leukemia 10.1
17 lymphopenia 10.1
18 47,xyy 10.1
19 acute graft versus host disease 10.1
20 chromosomal triplication 10.1
21 splenomegaly 10.1
22 mental retardation, autosomal dominant 29 10.1 PBX1 ABL1
23 b-lymphoblastic leukemia/lymphoma with hypodiploidy 10.1 PBX1 ABL1
24 philadelphia-negative chronic myeloid leukemia 10.1 BCR ABL1
25 myelophthisic anemia 10.0 ANPEP ABL1
26 b-lymphoblastic leukemia/lymphoma with hyperdiploidy 10.0 PBX1 ABL1
27 hypereosinophilic syndrome 10.0
28 leukemia 10.0
29 b-lymphoblastic leukemia/lymphoma 10.0
30 posttransplant acute limbic encephalitis 10.0
31 childhood acute lymphocytic leukemia 9.9 PBX1 IKZF1 ABL1
32 mixed phenotype acute leukemia 9.9 ANPEP ABL1
33 b-lymphoblastic leukemia/lymphoma with iamp21 9.7 ZNF384 PBX1 IKZF1 ABL1
34 central nervous system leukemia 9.6 CD19 ANPEP
35 childhood leukemia 9.6 PBX1 BCR ABL1
36 pancytopenia 9.4 IKZF1 CD19 ANPEP
37 myeloproliferative neoplasm 9.2 BCR ANPEP ABL1
38 hematologic cancer 9.1 IKZF1 CD19 BCR ABL1
39 leukemia, chronic myeloid 9.0 IKZF1 EVPL CD19 BCR ABL1

Graphical network of the top 20 diseases related to B-Cell Adult Acute Lymphocytic Leukemia:

Diseases related to B-Cell Adult Acute Lymphocytic Leukemia

Symptoms & Phenotypes for B-Cell Adult Acute Lymphocytic Leukemia

UMLS symptoms related to B-Cell Adult Acute Lymphocytic Leukemia:

bone pain

MGI Mouse Phenotypes related to B-Cell Adult Acute Lymphocytic Leukemia:

# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.61 ABL1 ANPEP BCR CD19 IKZF1 MSI2
2 immune system MP:0005387 9.28 ABL1 ANPEP BCR CD19 IKZF1 MSI2

Drugs & Therapeutics for B-Cell Adult Acute Lymphocytic Leukemia

Drugs for B-Cell Adult Acute Lymphocytic Leukemia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 124)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Methylprednisolone Approved, Vet_approved Phase 3 83-43-2 6741
Prednisolone phosphate Approved, Vet_approved Phase 3 302-25-0
Methylprednisolone hemisuccinate Approved Phase 3 2921-57-5
Prednisolone Approved, Vet_approved Phase 3 50-24-8 5755
5 Prednisolone acetate Approved, Vet_approved Phase 3 52-21-1
Levoleucovorin Approved, Investigational Phase 3 68538-85-2
Mitoxantrone Approved, Investigational Phase 3 65271-80-9 4212
Ifosfamide Approved Phase 3 3778-73-2 3690
Lenograstim Approved, Investigational Phase 3 135968-09-1
Sargramostim Approved, Investigational Phase 3 83869-56-1, 123774-72-1
Carmustine Approved, Investigational Phase 3 154-93-8 2578
Dactinomycin Approved, Investigational Phase 3 50-76-0 457193 2019
Fludarabine Approved Phase 3 21679-14-1, 75607-67-9 30751
Etoposide Approved Phase 3 33419-42-0 36462
rituximab Approved Phase 3 174722-31-7 10201696
Melphalan Approved Phase 3 148-82-3 460612 4053
Prednisolone hemisuccinate Experimental Phase 3 2920-86-7
18 Molgramostim Investigational Phase 3 99283-10-0
19 Methylprednisolone Acetate Phase 3
20 Protective Agents Phase 3
21 Micronutrients Phase 3
22 Vitamins Phase 3
23 Antidotes Phase 3
24 Nutrients Phase 3
25 Trace Elements Phase 3
26 Calcium, Dietary Phase 3
27 Analgesics Phase 3
Isophosphamide mustard Phase 3 0
29 Adjuvants, Immunologic Phase 3
30 Protein Kinase Inhibitors Phase 3
31 Etoposide phosphate Phase 3
32 Imatinib Mesylate Phase 3 220127-57-1 123596
33 Antineoplastic Agents, Immunological Phase 3
Calcium Nutraceutical Phase 3 7440-70-2 271
Vindesine Approved, Investigational Phase 2 59917-39-4, 53643-48-4 40839
Teniposide Approved Phase 2 29767-20-2 34698
Idarubicin Approved Phase 2 58957-92-9 42890
Bortezomib Approved, Investigational Phase 2 179324-69-7 387447 93860
Promethazine Approved, Investigational Phase 2 60-87-7 4927
Acetaminophen Approved Phase 2 103-90-2 1983
Clofarabine Approved, Investigational Phase 2 123318-82-1 119182
Diphenhydramine Approved, Investigational Phase 2 58-73-1, 147-24-0 3100
Hydrocortisone Approved, Vet_approved Phase 2 50-23-7 5754
Hydrocortisone acetate Approved, Vet_approved Phase 2 50-03-3
Thiotepa Approved, Investigational Phase 2 52-24-4 5453
Blinatumomab Approved, Investigational Phase 2 853426-35-4
Aspartic acid Approved, Nutraceutical Phase 2 56-84-8 5960
48 Veltuzumab Investigational Phase 1, Phase 2 728917-18-8
Epratuzumab Investigational Phase 2 205923-57-5
Veliparib Investigational Phase 1, Phase 2 912444-00-9 11960529

Interventional clinical trials:

(show all 44)
# Name Status NCT ID Phase Drugs
1 High Risk B-Precursor Acute Lymphoblastic Leukemia Unknown status NCT00075725 Phase 3 cyclophosphamide;cytarabine;daunorubicin hydrochloride;dexamethasone;doxorubicin hydrochloride;leucovorin calcium;mercaptopurine;methotrexate;pegaspargase;prednisone;thioguanine;vincristine sulfate
2 A Pilot Study of Dose Intensification of Methotrexate in Patients With Advanced-Stage (III/IV) Small Non-Cleaved Cell Non-Hodgkins Lymphoma and B-Cell All Completed NCT00005977 Phase 3 cyclophosphamide;cytarabine;dexamethasone;doxorubicin hydrochloride;etoposide;ifosfamide;leucovorin calcium;methotrexate;vincristine sulfate
3 A Phase III Trial Comparing ARA-C/High-Dose Mitoxantrone ("ALL-2') to A Standard Vincristine/Prednisone Based Regimen ('L-20') as Induction Therapy For Adult Patients With Acute Lymphoblastic Leukemia (ALL): The ALL-4 Protocol Completed NCT00002766 Phase 3 carmustine;cyclophosphamide;cytarabine;daunorubicin hydrochloride;doxorubicin hydrochloride;etoposide;mercaptopurine;methotrexate;mitoxantrone hydrochloride;pegaspargase;prednisone;vincristine sulfate
4 A Randomized Trial for Adults With Newly Diagnosed Acute Lymphoblastic Leukemia Recruiting NCT01085617 Phase 3 cyclophosphamide;cytarabine;daunorubicin hydrochloride;etoposide;fludarabine phosphate;imatinib mesylate;melphalan;mercaptopurine;methotrexate;nelarabine;pegaspargase;vincristine sulfate
5 Phase I/II Study Combining Humanised Anti-CD20 (Veltuzumab), Anti-CD22 (Epratuzumab) and Both Monoclonal Antibodies With Intensive Chemotherapy in Adults With Recurrent or Refractory B-precursor Acute Lymphoblastic Leukaemia (ALL) Unknown status NCT01279707 Phase 1, Phase 2
6 MULTICENTRE TRIAL OF INTENSIFIED THERAPY FOR ADULT ALL (O5/93) Unknown status NCT00002531 Phase 2 asparaginase;cyclophosphamide;cytarabine;daunorubicin hydrochloride;dexamethasone;doxorubicin hydrochloride;etoposide;ifosfamide;leucovorin calcium;mercaptopurine;methotrexate;mitoxantrone hydrochloride;prednisolone;teniposide;thioguanine;vincristine sulfate;vindesine
7 A Phase II Trial of 506U78 (IND 52611) in Patients With Relapsed or Refractory Non T-cell Acute Lymphoblastic Leukemia (ALL) Completed NCT00006020 Phase 2 nelarabine
8 Phase II Study of Adult Acute Lymphoblastic Leukaemia (ALL): Imatinib in Combination With Chemotherapy in Ph+ Patients, and Post-remissional Treatment Intensification in High-risk Ph- Patients, With Minimal Residual Disease Monitoring. Completed NCT00458848 Phase 2 asparaginase;daunorubicin hydrochloride;etoposide;idarubicin;imatinib mesylate;mercaptopurine;methotrexate;methylprednisolone;mitoxantrone hydrochloride;prednisone;vincristine sulfate
9 Addition of Pre- and Post-Transplant Rituximab for Patients Undergoing Non-myeloablative Allogeneic Hematopoietic Cell Transplantation With Relapsed or Refractory CD20+ B-Cell Malignancies Completed NCT00867529 Phase 2
10 A Phase II Study of Subcutaneous Bortezomib in Combination With Chemotherapy (VXLD) for Relapsed/Refractory Adult Acute Lymphoblastic Leukemia Completed NCT01769209 Phase 2 Bortezomib;Doxorubicin hydrochloride (HCl);PEG-Asparaginase;Vincristine sulfate;Dexamethasone;Cytarabine;Methotrexate
11 A Phase I/II Study of Combined Enrichment of CD34+ Cells and Depletion of B-Cells From Peripheral Blood Stem Cell Components for Patients With B-Lymphoid Malignancies Completed NCT00003874 Phase 1, Phase 2
12 S0910, A Phase II Study of Epratuzumab (NSC-716711) in Combination With Cytarabine and Clofarabine for Patients With Relapsed or Refractory Ph- Negative Precursor B-Cell Acute Lymphoblastic Leukemia Completed NCT00945815 Phase 2 clofarabine;cytarabine
13 A Phase II Trial of Cytarabine and Clofarabine in Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia (ALL) Completed NCT00337168 Phase 2 clofarabine;cytarabine
14 Phase I/II Radioimmunotherapy of Non-Hodgkin's Lymphoma With High-Dose 90Y-Labeled Humanized LL2 Anti-CD-22 Antibody and Peripheral Blood Stem Cell Rescue Completed NCT00004107 Phase 1, Phase 2
15 Phase II Trial of Intensive, Short-Course Combination Chemotherapy in the Treatment of Newly Diagnosed Patients With Poor-Risk Nonlymphoblastic Lymphoma and Acute B-Lymphoblastic Leukemia and in Patients With Recurrent Non-Hodgkin's Lymphoma Completed NCT00002471 Phase 2 asparaginase;cyclophosphamide;cytarabine;daunorubicin hydrochloride;dexamethasone;etoposide;leucovorin calcium;methotrexate;methylprednisolone;therapeutic hydrocortisone;thiotepa;vincristine sulfate
16 A Phase II Pilot Trial of Bortezomib (PS-341, Velcade) in Combination With Intensive Re-Induction Therapy for Children With Relapsed Acute Lymphoblastic Leukemia (ALL) and Lymphoblastic Lymphoma (LL) Completed NCT00873093 Phase 2 L-asparaginase;doxorubicin hydrochloride;therapeutic hydrocortisone;vincristine sulfate;cytarabine;prednisone;bortezomib;pegaspargase;methotrexate;etoposide phosphate;cyclophosphamide;leucovorin calcium;High Dose MTX
17 A Phase 1b/2a Study of ABT-888 in Combination With Bendamustine +/- Rituximab in Lymphoma, Multiple Myeloma and Solid Tumors Completed NCT01326702 Phase 1, Phase 2 Bendamustine Hydrochloride;Veliparib
18 A Phase 2 Study of Ibrutinib and Blinatumomab in Relapsed and Refractory B-Cell Acute Lymphoblastic Leukemia Recruiting NCT02997761 Phase 2 Ibrutinib
19 An Intergroup Phase II Clinical Trial for Adolescents and Young Adults With Untreated Acute Lymphoblastic Leukemia (ALL) Active, not recruiting NCT00558519 Phase 2 cyclophosphamide;cytarabine;daunorubicin hydrochloride;dexamethasone;doxorubicin hydrochloride;mercaptopurine;methotrexate;pegaspargase;thioguanine;vincristine sulfate
20 Blinatumomab for Minimal Residual Disease (MRD) in Pre-B Cell Acute Lymphoblastic Leukemia Patients Following Hematopoietic Cell Transplantation: A Canadian, Multicentre Trial Not yet recruiting NCT04044560 Phase 2
21 A Phase 2 Study to Determine the Efficacy of the BTK Inhibitor Ibrutinib (PCI-32765) in Patients With Relapsed or Refractory Precursor-B Lymphoblastic Leukemia (B-ALL) Terminated NCT02129062 Phase 2 Ibrutinib
22 A Phase I/II Trial of Romidepsin, Rituximab and Lenalidomide (R3) in Relapsed/Refractory B Cell Lymphomas Including Transformed Follicular Lymphoma Withdrawn NCT02281279 Phase 1, Phase 2 lenalidomide;romidepsin
23 A Phase II Study of Combination Nilotinib and Hyper-CVAD in Patients Newly Diagnosed With Philadelphia-Chromosome Positive Acute Lymphoblastic Leukemia or Chronic Myeloid Leukemia Blast-Phase Lymphoid Lineage Withdrawn NCT01670084 Phase 2 nilotinib;cyclophosphamide;doxorubicin hydrochloride;vincristine sulfate;methotrexate;cytarabine;prednisone;mesna;dexamethasone;leucovorin calcium
24 A Phase I Trial Of Rituximab And Interleukin-2 Completed NCT00010192 Phase 1
25 Phase I Study of MLN 9708 in Addition to Chemotherapy for the Treatment of Acute Lymphoblastic Leukemia in Older Adults Completed NCT02228772 Phase 1 MLN 9708;Vincristine;Cytarabine;Doxorubicin;Mercaptopurine;Cyclophosphamide;Methotrexate
26 Phase I Study of Adoptive Immunotherapy With CD8 Minor Histocompatibility (H) Antigen-Specific CTL Clones for Patients With Relapsed of AML or ALL After Allogeneic Hematopoietic Stem Cell Transplant Completed NCT00107354 Phase 1 cytarabine;etoposide;mitoxantrone hydrochloride
27 Phase I Study of the Aurora Kinase a Inhibitor MLN8237 in Combination With the Histone Deacetylase Inhibitor Vorinostat in Lymphoid Malignancies Completed NCT01567709 Phase 1 Alisertib;Vorinostat
28 A Phase I Study of DT2219ARL, A Bispecific Singe Chain Immunotoxin for the Treatment of Relapsed or Refractory CD19(+), CD22(+) B-Lineage Leukemia or Lymphoma Completed NCT00889408 Phase 1
29 A Phase I Study of Photochemically Treated Donor T-Cell Supplements in HLA Haplotype Mismatched Hematopoietic Stem Cell Transplantation Completed NCT00005092 Phase 1 Cyclophosphamide;Psoralen;Thiotepa
30 A Phase I Trial of Palbociclib in Combination With Dexamethasone in Relapsed or Refractory Adult B-Cell Acute Lymphoblastic Leukemia (ALL) Recruiting NCT03472573 Phase 1 Palbociclib;Dexamethasone
31 A Phase I Study of Administrating CD19 Chimeric Antigen Receptor Expressing T Cells Followed by Allogeneic Stem Cell Transplantation in Patients With Refractory CD19+ B-linage Leukemia/Lymphoma Recruiting NCT03110640 Phase 1 Fludarabine;Cyclophosphamide
32 A Phase I Study of Combination Therapy With Anti-CD19 and Anti-CD22 Immunotoxins (Combotox) in Adults With Refractory/Relapse Acute Lymphoblastic Leukemia Recruiting NCT00450944 Phase 1
33 A Two-Stage Phase 1 Open-Label Study of huJCAR014, CD19-Targeted Chimeric Antigen Receptor (CAR)-Modified T Cells Bearing a Human Binding Domain, in Adult Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma and Acute Lymphocytic Leukemia Recruiting NCT03103971 Phase 1 Cyclophosphamide;Fludarabine
34 Phase I Dose-Escalation Study of CPI-613, in Combination With Bendamustine and Rituximab, in Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma Terminated NCT02168907 Phase 1 6,8-bis(benzylthio)octanoic acid;bendamustine hydrochloride
35 A Phase 1 Study of the Deglycosylated Ricin A Chain-containing Combined Anti-CD19 and Anti-CD22 Immunotoxin Combotox in Combination With High-Dose Cytarabine in Adult Relapsed or Refractory B-lineage Acute Lymphoblastic Leukemia Terminated NCT01408160 Phase 1 Cytarabine
36 Phase I and Pharmacokinetic Study of Ibrutinib in HIV-Infected Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma or Multiple Myeloma Terminated NCT02109224 Phase 1 Ibrutinib
37 Genomic Analysis of Adolescent and Young Adult Acute Lymphoblastic Leukemia Unknown status NCT01653613
38 Intensified PEG-Asparaginase in High Risk Acute Lymphoblastic Leukemia (ALL): A Pilot Study Unknown status NCT00866307 pegaspargase;cytarabine;vincristine sulfate;doxorubicin hydrochloride;cyclophosphamide;prednisone;dexamethasone;methotrexate;daunorubicin hydrochloride;mercaptopurine;thioguanine
39 Micro RNA Expression Analysis in B-Lineage Adult Acute Lymphoblastic Leukemia From ALL Trial, E2993, Including Patients With Various Cytogenetic and Molecular Abnormalities Completed NCT01505699
40 Identifying Rare Genetic Variants Involved in High Risk Acute Lymphoblastic Leukemia (ALL) Via Pooled DNA Sequencing Completed NCT01119586
41 Young Adult Acute Lymphoid Leukemia (ALL): Intensification of Pediatric AIEOP LLA-2000 Treatment Completed NCT01156883 asparaginase;cyclophosphamide;cytarabine;daunorubicin hydrochloride;dexamethasone;doxorubicin hydrochloride;ifosfamide;mercaptopurine;methotrexate;methylprednisolone;prednisone;thioguanine;vincristine sulfate;vindesine
42 Multicenter Trial Treatment of Philadelphia Chromosome Negative (Ph-) B-lineage Acute Lymphoblastic Leukemia (ALL) of Young Adults (18-59 Years). Recruiting NCT02617004
43 A Pilot Study of Intravenous EZN-2285 (SC-PEG E. Coli L-asparaginase, IND# 100594) or Intravenous Oncaspar® in the Treatment of Patients With High-Risk Acute Lymphoblastic Leukemia (ALL) Active, not recruiting NCT00671034 calaspargase pegol;calaspargase pegol;Pegaspargase;DOXOrubicin Hydrochloride;Cytarabine;Prednisone;methotrexate;cyclophosphamide;mercaptopurine tablet;Dexamethasone;thioguanine;DAUNOrubicin Hydrochloride;vincristine sulfate
44 A Phase I Study of Vaccination With Autologous CD40-Activated Acute Lymphoblastic Leukemia Cells Terminated NCT00020670 Early Phase 1

Search NIH Clinical Center for B-Cell Adult Acute Lymphocytic Leukemia

Genetic Tests for B-Cell Adult Acute Lymphocytic Leukemia

Anatomical Context for B-Cell Adult Acute Lymphocytic Leukemia

MalaCards organs/tissues related to B-Cell Adult Acute Lymphocytic Leukemia:

B Cells, B Lymphoblasts, T Cells, Bone, Myeloid

Publications for B-Cell Adult Acute Lymphocytic Leukemia

Articles related to B-Cell Adult Acute Lymphocytic Leukemia:

# Title Authors PMID Year
Suppression of miR-708 inhibits the Wnt/β-catenin signaling pathway by activating DKK3 in adult B-all. 61
28969056 2017
Atypical BCR-ABL1 fusion transcripts in adult B-acute lymphoblastic leukemia, including a novel fusion transcript-e8a1. 61
26942999 2016
Development-associated immunophenotypes reveal the heterogeneous and individualized early responses of adult B-acute lymphoblastic leukemia. 61
27559941 2016
Monoclonal antibodies and immune therapies for adult precursor B-acute lymphoblastic leukemia. 61
26921100 2016
Prognostic significance of MSI2 predicts unfavorable outcome in adult B-acute lymphoblastic leukemia. 61
25090928 2015
BCR-ABL1 and CD66c exhibit high concordance in minimal residual disease detection of adult B-acute lymphoblastic leukemia. 61
26045902 2015
Prognostic significance of monitoring leukemia-associated immunophenotypes by eight-color flow cytometry in adult B-acute lymphoblastic leukemia. 61
23955588 2013
Fingerprinting acute leukemia: DNA methylation profiling of B-acute lymphoblastic leukemia. 61
23148371 2012
Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia. 61
23107779 2012

Variations for B-Cell Adult Acute Lymphocytic Leukemia

Expression for B-Cell Adult Acute Lymphocytic Leukemia

Search GEO for disease gene expression data for B-Cell Adult Acute Lymphocytic Leukemia.

Pathways for B-Cell Adult Acute Lymphocytic Leukemia

GO Terms for B-Cell Adult Acute Lymphocytic Leukemia

Biological processes related to B-Cell Adult Acute Lymphocytic Leukemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuromuscular process controlling balance GO:0050885 9.37 BCR ABL1
2 thymus development GO:0048538 9.32 PBX1 ABL1
3 spleen development GO:0048536 9.26 PBX1 ABL1
4 platelet-derived growth factor receptor signaling pathway GO:0048008 9.16 BCR ABL1
5 positive regulation of release of sequestered calcium ion into cytosol GO:0051281 8.96 CD19 ABL1
6 B cell proliferation involved in immune response GO:0002322 8.62 CD19 ABL1

Sources for B-Cell Adult Acute Lymphocytic Leukemia

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
31 HPO
32 ICD10
33 ICD10 via Orphanet
37 LifeMap
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
54 Novoseek
57 OMIM via Orphanet
61 PubMed
70 Tocris
72 UMLS via Orphanet
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