MCID: BCT007
MIFTS: 56

Bacterial Meningitis

Categories: Infectious diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Bacterial Meningitis

MalaCards integrated aliases for Bacterial Meningitis:

Name: Bacterial Meningitis 12 75 53 3 15 17
Meningitis, Bacterial 53 44 72
Meningitis Bacterial 55

Classifications:



External Ids:

Disease Ontology 12 DOID:9470
ICD9CM 35 320 320.9
MeSH 44 D016920
NCIt 50 C118297
SNOMED-CT 68 95883001
ICD10 33 G00 G00.9
UMLS 72 C0085437

Summaries for Bacterial Meningitis

CDC : 3 Bacterial meningitis is very serious and can be deadly. Death can occur in as little as a few hours. Most people recover from meningitis. However, permanent disabilities (such as brain damage, hearing loss, and learning disabilities) can result from the infection. Several types of bacteria can cause meningitis. Leading causes in the United States include Streptococcus pneumoniae Group B Streptococcus Neisseria meningitidis Haemophilus influenzae Listeria monocytogenes These bacteria can also be associated with another serious illness, sepsis. Sepsis is the body’s extreme response to infection. Without timely treatment, sepsis can quickly lead to tissue damage, organ failure, and death.

MalaCards based summary : Bacterial Meningitis, also known as meningitis, bacterial, is related to streptococcal meningitis and aseptic meningitis. An important gene associated with Bacterial Meningitis is CRP (C-Reactive Protein), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs Phenytoin and Acetaminophen have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and spinal cord, and related phenotypes are homeostasis/metabolism and cardiovascular system

Disease Ontology : 12 A meningitis that has material basis in a bacterial infection.

Wikipedia : 75 Meningitis is an acute inflammation of the protective membranes covering the brain and spinal cord,... more...

Related Diseases for Bacterial Meningitis

Diseases in the Meningitis family:

Viral Meningitis Chronic Meningitis
Bacterial Meningitis

Diseases related to Bacterial Meningitis via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 638, show less)
# Related Disease Score Top Affiliating Genes
1 streptococcal meningitis 33.3 TNF CRP CFP
2 aseptic meningitis 33.0 TNF IL1B IL10 CXCL8
3 viral meningitis 32.7 IL6 CXCL8 CRP
4 cerebral palsy 32.4 TNF MMP8 IL6 IL1B
5 haemophilus influenzae 32.3 TNF TLR2 IL1B CXCL8
6 tuberculous meningitis 31.3 TNF TLR2 MMP9 CXCL8
7 neisseria meningitidis infection 31.1 TLR4 TLR2 CFP
8 brain edema 30.8 MMP9 IL6 IL1B
9 exanthem 30.7 TNF TLR9 IL6 CRP
10 acute cystitis 30.6 IL6 CXCL8 CRP
11 pharyngitis 30.6 IL1B CXCL8 CRP
12 brain injury 30.5 S100B IL6 IL10
13 respiratory failure 30.3 TNF PIK3C2A CXCL8 CRP
14 diverticulitis 30.3 TNF MMP9 CRP
15 traumatic brain injury 30.3 S100B IL6 IL10
16 crohn's disease 30.3 TNF TLR9 IL10 CRP
17 reactive arthritis 30.3 TNF MMP8 IL10 CRP
18 hematopoietic stem cell transplantation 30.3 TNF IL6 IL10
19 infective endocarditis 30.2 TNF TLR2 IL6 CRP
20 meningitis 30.2 TNF TLR9 TLR2 PTGDS MMP9 IL6
21 septic arthritis 30.2 TLR9 TLR4 TLR2 CXCL8 CRP
22 pulmonary tuberculosis 30.2 TNF TLR9 TLR2 IL10
23 purpura 30.1 TNF IL6 CRP
24 mycobacterium tuberculosis 1 30.0 TNF TLR9 TLR4 TLR2 IL10
25 acquired immunodeficiency syndrome 30.0 TNF IL6 IL1B IL10
26 apnea, obstructive sleep 30.0 TNF IL6 CRP
27 suppurative otitis media 29.9 TLR9 TLR4 TLR2 IL1B CRP
28 osteomyelitis 29.9 TNF IL6 IL1B IL10 CXCL8
29 pericardial effusion 29.8 PIK3C2A IL6 CRP
30 spondylitis 29.8 TNF IL6 CRP
31 end stage renal failure 29.8 TNF IL6 CRP
32 bacterial sepsis 29.8 TNF TLR4 IL10 CXCL8 CRP
33 viral encephalitis 29.8 TNF IL6 IL1B IL10 CXCL8
34 adult-onset still's disease 29.8 TNF IL6 IL1B CRP
35 myeloma, multiple 29.8 TNF TLR9 IL6 CXCL8 CRP
36 pericarditis 29.8 TNF IL6 IL1B CRP
37 cholangitis 29.8 TNF IL6 CRP
38 central nervous system disease 29.7 TNF TLR9 MMP9 IL6 IL1B
39 autoimmune disease 29.7 TNF TLR9 IL6 IL1B IL10
40 scrub typhus 29.7 TNF TLR4 TLR2 IL1B IL10 CRP
41 adult respiratory distress syndrome 29.7 TNF IL6 IL10 CXCL8
42 toxic shock syndrome 29.7 TNF TLR4 TLR2 IL6 IL1B IL10
43 acute pyelonephritis 29.7 IL6 IL10 CXCL8 CRP
44 otitis media 29.6 TNF TLR4 TLR2 IL6 IL1B IL10
45 transverse myelitis 29.5 TNF MMP9 IL6 IL10 CXCL8
46 pertussis 29.5 TNF TLR4 IL6 IL1B IL10
47 tonsillitis 29.5 TNF TLR9 IL6 IL1B CXCL8
48 common variable immunodeficiency 29.4 TNF TLR9 TLR2 IL6 IL10
49 bacterial pneumonia 29.4 TLR9 TLR4 IL6 CXCL8 CRP
50 cerebrovascular disease 29.4 TNF TLR4 MMP9 IL6 CRP
51 salmonellosis 29.3 TLR4 IL1B CKB
52 kawasaki disease 29.3 TNF MMP9 IL6 IL10 CRP
53 gastroenteritis 29.3 TNF IL6 IL1B IL10 CXCL8 CRP
54 endocarditis 29.3 TNF TLR2 PIK3C2A IL6 IL10 CXCL8
55 arthritis 29.2 TNF MMP9 IL6 IL1B IL10 CXCL8
56 viral infectious disease 29.1 TNF TLR9 IL6 IL1B IL10 CXCL8
57 lyme disease 29.1 TNF TLR2 MMP9 IL6 IL1B CRP
58 peritonitis 29.0 TNF TLR2 IL6 IL1B IL10 CXCL8
59 sleep apnea 28.9 TNF S100B IL6 IL1B CXCL8 CRP
60 brucellosis 28.9 TNF TLR4 IL6 IL10 CXCL8 CRP
61 multiple sclerosis 28.8 TNF PTGDS MMP9 IL6 IL1B IL10
62 middle ear disease 28.6 TNF TLR9 TLR4 TLR2 IL6 IL1B
63 nervous system disease 28.6 TNF TLR9 S100B MMP9 IL6 IL1B
64 pyelonephritis 28.6 TNF TLR4 IL6 IL1B IL10 CXCL8
65 bacterial infectious disease 28.5 TNF TLR9 TLR4 TLR2 IL6 IL1B
66 human immunodeficiency virus type 1 28.4 TNF S100B IL6 IL10 CR1 CFP
67 diabetes mellitus 28.3 TNF PTGDS PIK3C2A IL6 IL1B CRP
68 proteasome-associated autoinflammatory syndrome 1 28.1 TNF TLR4 TLR2 MMP9 IL6 IL1B
69 lung disease 27.9 TNF TLR9 TLR2 MMP9 MMP8 IL6
70 systemic lupus erythematosus 27.7 TNF TLR9 TLR4 TLR2 IL6 IL1B
71 pneumonia 27.5 TNF TLR9 TLR4 TLR2 PIK3C2A IL6
72 malaria 27.0 TNF TLR9 TLR4 TLR2 MMP9 IL6
73 haemophilus meningitis 12.0
74 meningococcal infection 11.7
75 meningococcal meningitis 11.6
76 listeria meningitis 11.5
77 pneumococcal meningitis 11.3
78 syphilitic meningitis 11.2
79 punctate inner choroidopathy 10.7 TNF IL10
80 ocular motor apraxia 10.7
81 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.7
82 tropical endomyocardial fibrosis 10.7 TNF IL10
83 endomyocardial fibrosis 10.7 TNF IL10
84 hydrocephalus 10.7
85 congenital hydrocephalus 10.7
86 mycobacterium chelonae 10.6 TLR2 CXCL8
87 drug reaction with eosinophilia and systemic symptoms 10.6 TNF CRP
88 congenital cytomegalovirus 10.6 TNF TLR2 IL1B
89 branchiootic syndrome 1 10.6
90 exudative glomerulonephritis 10.6 TNF IL1B CXCL8
91 keratoconjunctivitis 10.6 TNF TLR9 CXCL8
92 mycobacterium marinum 10.6 TLR2 CXCL8
93 chronic follicular conjunctivitis 10.6 MMP9 IL1B
94 mucocutaneous leishmaniasis 10.6 TNF TLR9 IL10
95 opisthorchiasis 10.6 TNF IL1B CXCL8
96 staphylococcal toxic shock syndrome 10.6 TNF IL1B
97 autoimmune inner ear disease 10.6 TNF MMP9
98 crohn's colitis 10.6 TNF IL1B CXCL8
99 dental pulp disease 10.6 TNF IL1B CXCL8
100 tungiasis 10.6 TNF IL10 CXCL8
101 mycobacterium abscessus 10.6 TNF TLR2 CXCL8
102 sensorineural hearing loss 10.6
103 filarial elephantiasis 10.6 TLR9 TLR2 IL10
104 coccidiosis 10.6 TNF TLR9 IL10
105 leprosy 3 10.5 TNF TLR2 IL10
106 palindromic rheumatism 10.5 TNF IL1B CRP
107 clonorchiasis 10.5 TNF IL10 CXCL8
108 autoimmune uveitis 10.5 TNF IL1B IL10
109 extrapulmonary tuberculosis 10.5 TLR2 IL1B IL10
110 lepromatous leprosy 10.5 TNF TLR2 IL10
111 neonatal meningitis 10.5
112 pleural disease 10.5 TNF IL1B CRP
113 testicular disease 10.5 TNF TLR2 IL10
114 neurosyphilis 10.5 TLR2 IL10 CXCL8
115 genital herpes 10.5 TLR9 TLR2 IL10
116 parasitic helminthiasis infectious disease 10.5 TNF TLR9 IL10
117 lymphatic system disease 10.5 TNF TLR9 CRP
118 trench fever 10.5 TNF TLR4 TLR2
119 prosthetic joint infection 10.5 TLR4 TLR2 IL1B
120 silicosis 10.5 TNF IL1B CXCL8
121 wells syndrome 10.5 IL1B CXCL8 CRP
122 myasthenic syndrome, congenital, 1a, slow-channel 10.5 CXCL8 CRP
123 atrophic gastritis 10.5 TNF IL1B CXCL8
124 multifocal choroiditis 10.5 TNF IL10
125 penicilliosis 10.5 TNF TLR4 TLR2
126 duodenal ulcer 10.5 TNF IL1B CXCL8
127 rare surgical neurologic disease 10.5
128 spondylarthropathy 10.5 TNF TLR4 TLR2
129 pleurisy 10.5 TNF CXCL8 CRP
130 seizure disorder 10.5
131 familial mediterranean fever 10.5 TNF IL1B CRP
132 irritable bowel syndrome 10.5 TNF TLR9 IL10
133 alveolar echinococcosis 10.5 TNF TLR4 TLR2
134 mycobacterium kansasii 10.5 TLR2 CXCL8
135 severe acute respiratory syndrome 10.5 TNF CXCL8 CRP
136 scorpion envenomation 10.4 TNF IL6
137 pyoderma 10.4 TNF MMP9 CXCL8
138 meningoencephalitis 10.4
139 amaurosis fugax 10.4 MMP9 MMP8
140 primary systemic mycosis 10.4 TNF TLR2 IL1B IL10
141 visual epilepsy 10.4
142 pleural empyema 10.4
143 intracranial hypertension 10.4
144 headache 10.4
145 pouchitis 10.4 TLR4 IL10 CXCL8
146 mollaret meningitis 10.4
147 opportunistic mycosis 10.4 TNF TLR9 TLR2 IL10
148 viral hepatitis 10.4 TNF TLR9 TLR2
149 alcohol dependence 10.4
150 scabies 10.4 IL10 CXCL8 CFP
151 peptic ulcer disease 10.4 TNF IL1B IL10 CXCL8
152 allergic contact dermatitis 10.4 TNF IL1B IL10 CXCL8
153 laryngitis 10.4 TNF IL6 IL1B
154 glossitis 10.4 TNF IL6 IL1B
155 streptococcus pneumonia 10.4
156 encephalitis 10.4
157 acute vascular insufficiency of intestine 10.4 TNF IL6 IL1B
158 osteosclerotic myeloma 10.4 TNF IL6 IL1B
159 poems syndrome 10.4 TNF IL6 IL1B
160 stachybotrys chartarum 10.3 TNF IL6 IL1B
161 nose disease 10.3 TNF TLR9 IL10 CXCL8
162 lentigo maligna melanoma 10.3 S100B MMP9
163 subdural empyema 10.3
164 bronchitis 10.3 TNF CXCL8 CRP
165 spondyloarthropathy 1 10.3 TNF TLR4 CRP
166 cold agglutinin disease 10.3 IL6 CRP
167 bronchiectasis 10.3 TLR2 MMP8 CXCL8
168 neutropenia 10.3
169 endometritis 10.3 TNF IL6 IL1B
170 vasculitis 10.3
171 carotid artery disease 10.3 MMP9 MMP8 CRP
172 eye lymphoma 10.3 TLR9 IL6 IL10
173 streptococcal toxic-shock syndrome 10.3 TNF IL6 CXCL8
174 recurrent corneal erosion 10.3 IL6 IL1B CXCL8
175 relapsing-remitting multiple sclerosis 10.3 TNF MMP9 IL10
176 uremic pruritus 10.3 IL6 IL1B CRP
177 dengue shock syndrome 10.3 TNF IL6 IL1B
178 bagassosis 10.3 IL6 IL1B CXCL8
179 intermediate uveitis 10.3 TNF IL6 IL10
180 demyelinating disease 10.3 TNF MMP9 IL1B IL10
181 secondary progressive multiple sclerosis 10.3 S100B MMP9 IL10
182 post-transplant lymphoproliferative disease 10.3 TNF IL6 IL10
183 chikungunya 10.3 TNF IL6 IL1B
184 dermatitis, atopic 10.3 TNF TLR9 IL10 CXCL8
185 meconium aspiration syndrome 10.3 TNF IL6 CXCL8
186 head injury 10.3
187 plasmodium vivax malaria 10.3 TNF IL6 IL10
188 vaginitis 10.3 IL6 IL1B CXCL8
189 vaginal disease 10.3 IL6 IL1B CXCL8
190 mesenteric lymphadenitis 10.3 TLR2 IL6 CRP
191 rheumatic fever 10.3 TNF IL6 IL10
192 spondyloarthropathy 10.3 TNF IL6 IL10
193 vibratory urticaria 10.3 MMP9 CXCL8
194 angioimmunoblastic lymphadenopathy with dysproteinemia 10.3 TNF IL6
195 47,xyy 10.3
196 cytokine deficiency 10.3
197 mixed connective tissue disease 10.3 TNF IL6 IL10
198 stomach disease 10.3 TLR9 MMP9 IL1B CXCL8
199 multicentric castleman disease 10.3 IL6 IL10 CRP
200 cryptogenic organizing pneumonia 10.3 PIK3C2A MMP9 CXCL8
201 rheumatic heart disease 10.3 TNF IL6 IL10
202 fasciitis 10.3 TNF IL6 CXCL8
203 diarrhea 10.2
204 cerebritis 10.2
205 dry eye syndrome 10.2 TNF TLR9 IL6
206 gingival disease 10.2 MMP8 IL6 IL1B
207 radiculopathy 10.2 IL6 IL10 CXCL8
208 temporal arteritis 10.2 TNF IL6 CRP
209 mondini dysplasia 10.2
210 febrile seizures 10.2
211 newborn respiratory distress syndrome 10.2 IL6 IL1B CXCL8
212 avian influenza 10.2 TNF IL6 CXCL8
213 invasive aspergillosis 10.2 TLR9 TLR4 TLR2 CXCL8
214 collagen disease 10.2 TLR9 IL6 CRP
215 vibrio vulnificus infection 10.2 PIK3C2A IL6
216 primary progressive multiple sclerosis 10.2 TNF S100B MMP9 IL10
217 autoimmune myocarditis 10.2 TNF IL6
218 pancreas disease 10.2 TNF IL6 CRP
219 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.2
220 ataxia and polyneuropathy, adult-onset 10.2
221 liver cirrhosis 10.2
222 leukocyte disease 10.2 TNF TLR9 IL6
223 carotid stenosis 10.2 TNF S100B MMP9 CRP
224 cysticercosis 10.2 TLR4 IL6 IL1B
225 mastitis 10.2 TLR2 IL6 CXCL8
226 mastoiditis 10.2
227 status epilepticus 10.2
228 cranial nerve palsy 10.2
229 48,xyyy 10.2
230 encephalocele 10.2
231 syndrome of inappropriate antidiuretic hormone 10.2
232 spasticity 10.2
233 skin disease 10.2 TNF TLR9 IL10 CXCL8
234 periodontosis 10.2 TNF TLR4 MMP9 CXCL8
235 esophagitis 10.2 IL6 IL1B CXCL8
236 rheumatic disease 10.2 TNF TLR9 IL1B IL10 CRP
237 pelvic inflammatory disease 10.2 TLR4 TLR2 MMP9 CRP
238 autoimmune gastritis 10.2 TNF IL6 IL1B IL10
239 cystic echinococcosis 10.2 TLR4 IL6 IL10
240 intervertebral disc disease 10.2 MMP9 IL6 IL1B
241 eales disease 10.2 TNF IL6 IL1B IL10
242 hydrocephalus, congenital, 1 10.2
243 myelitis 10.2
244 commensal bacterial infectious disease 10.1 TNF IL6 IL1B IL10
245 complex regional pain syndrome 10.1 TNF IL6 IL1B IL10
246 cardiogenic shock 10.1 TNF PIK3C2A IL6
247 tropical spastic paraparesis 10.1 MMP9 IL6 IL10
248 fungal keratitis 10.1 TLR4 TLR2 MMP9 MMP8
249 chronic mucocutaneous candidiasis 10.1 TNF IL6 IL1B IL10
250 autoimmune disease of eyes, ear, nose and throat 10.1 TNF TLR9 IL6 IL10
251 chronic fatigue syndrome 10.1 TNF IL6 IL1B IL10
252 graft-versus-host disease 10.1 TNF IL6 IL1B IL10
253 uveal disease 10.1 TNF TLR9 IL6 IL10
254 pulpitis 10.1 TNF IL6 IL1B CXCL8
255 hypersensitivity reaction type iii disease 10.1 TNF TLR9 IL6 CRP
256 bacteriuria 10.1 TLR4 IL6 CXCL8
257 acute respiratory distress syndrome 10.1 TNF IL6 IL1B CXCL8
258 ear malformation 10.1
259 yemenite deaf-blind hypopigmentation syndrome 10.1
260 meningocele 10.1
261 obstructive hydrocephalus 10.1
262 alcohol use disorder 10.1
263 thrombocytosis 10.1
264 measles 10.1
265 encephalopathy 10.1
266 juvenile rheumatoid arthritis 10.1 TNF IL6 IL1B CRP
267 overnutrition 10.1 TNF IL6 CRP
268 crimean-congo hemorrhagic fever 10.1 TNF PIK3C2A IL6
269 pneumoconiosis 10.1 TNF IL6 IL1B CXCL8
270 cytomegalovirus infection 10.1 TNF IL6 IL1B CXCL8
271 periodontitis, chronic 10.1 TLR2 MMP8 IL6 IL1B
272 monocytic leukemia 10.1 TNF IL6 IL1B CXCL8
273 immune system disease 10.1 TNF TLR9 IL6 IL10
274 urinary system disease 10.1 TNF TLR9 IL6 CRP
275 louse-borne relapsing fever 10.1 TNF IL6 CXCL8 CRP
276 placenta disease 10.1 TLR9 IL6 IL1B CXCL8
277 dengue hemorrhagic fever 10.1 TNF IL6 IL10 CXCL8
278 psoriatic arthritis 10.1 TNF IL6 IL1B CRP
279 aortic disease 10.1 MMP9 IL6 CRP
280 currarino syndrome 10.1
281 spinal arachnoiditis 10.1
282 hydrops, lactic acidosis, and sideroblastic anemia 10.1
283 epidural abscess 10.1
284 listeriosis 10.1
285 arachnoiditis 10.1
286 communicating hydrocephalus 10.1
287 endophthalmitis 10.1
288 herpes simplex 10.1
289 chickenpox 10.1
290 cerebrospinal fluid leak 10.1
291 alcoholic hepatitis 10.1 TNF IL6 IL10 CXCL8
292 fatty liver disease 10.1 TNF IL6 IL1B CXCL8
293 hemorrhagic fever with renal syndrome 10.1 TNF IL6 CXCL8 CRP
294 extrinsic allergic alveolitis 10.1 IL6 IL1B IL10 CXCL8
295 myositis fibrosa 10.1 TLR9 TLR4 TLR2 PIK3C2A
296 obstructive jaundice 10.1 TNF IL6 CXCL8 CRP
297 pulmonary fibrosis, idiopathic 10.1 TNF TLR9 MMP9 IL1B CXCL8
298 cutaneous leishmaniasis 10.1 TNF TLR9 TLR4 TLR2 IL10
299 aspergillosis 10.1 TNF TLR9 TLR4 TLR2 IL10
300 intermediate coronary syndrome 10.1 PIK3C2A IL6 CRP
301 connective tissue disease 10.1 TNF TLR9 IL6 IL10
302 vascular disease 10.0 TNF MMP9 IL6 CRP
303 angina pectoris 10.0 PIK3C2A IL6 CRP
304 gastrointestinal system cancer 10.0 TNF TLR9 MMP9 IL6
305 lymphadenitis 10.0 TNF TLR4 IL1B IL10 CXCL8
306 pain agnosia 10.0
307 pituitary apoplexy 10.0
308 fungal meningitis 10.0
309 locked-in syndrome 10.0
310 quadriplegia 10.0
311 anaerobic meningitis 10.0
312 labyrinthitis 10.0
313 encephalomalacia 10.0
314 lactic acidosis 10.0
315 meningoencephalocele 10.0
316 back pain 10.0
317 meningitis and encephalitis 10.0
318 sudden infant death syndrome 10.0 TNF IL6 IL1B IL10
319 ileitis 10.0 TNF TLR4 TLR2 IL6
320 takayasu arteritis 10.0 TNF MMP9 IL6 CRP
321 spinal cord injury 10.0 TNF MMP9 IL6 CXCL8
322 plasmodium falciparum malaria 10.0 TNF TLR9 IL10 CR1
323 acute pancreatitis 10.0 IL6 IL10 CXCL8 CRP
324 acute transverse myelitis 10.0 MMP9 IL6 IL10 CXCL8
325 coronary stenosis 10.0 PIK3C2A IL6 CRP
326 keratitis, hereditary 10.0 TLR9 TLR4 TLR2 MMP9 IL1B
327 cryopyrin-associated periodic syndrome 10.0 IL6 CRP
328 neural tube defects 10.0
329 torticollis 10.0
330 epidemic typhus 10.0
331 immunoglobulin alpha deficiency 10.0
332 penicillin allergy 10.0
333 cryptococcal meningitis 10.0
334 strongyloidiasis 10.0
335 hemiplegia 10.0
336 disseminated intravascular coagulation 10.0
337 tetanus 10.0
338 cerebral arteritis 10.0
339 cauda equina syndrome 10.0
340 guillain-barre syndrome 10.0
341 thrombocytopenia 10.0
342 inappropriate adh syndrome 10.0
343 pituitary adenoma 10.0
344 thrombophlebitis 10.0
345 paraplegia 10.0
346 lymphopenia 10.0
347 adenoma 10.0
348 rubella 10.0
349 lupus erythematosus 10.0
350 hypoglycemia 10.0
351 cerebral hypoxia 10.0
352 hypotonia 10.0
353 atherosclerosis susceptibility 10.0 TNF TLR4 IL6 CRP
354 peripheral nervous system disease 10.0 TNF TLR9 IL6
355 aphthous stomatitis 10.0 TNF TLR2 IL6 IL1B IL10
356 hemophagocytic lymphohistiocytosis 10.0 TNF IL10 CXCL8 CR1
357 lacrimal apparatus disease 9.9 TNF TLR9 IL6 IL1B IL10
358 keratoconjunctivitis sicca 9.9 TNF TLR9 IL6 IL1B IL10
359 autoimmune disease of central nervous system 9.9 TNF TLR9 IL6 IL1B IL10
360 central nervous system vasculitis 9.9 TNF TLR9 IL6 IL1B CRP
361 pyelitis 9.9 TLR4 IL6 CXCL8 CRP
362 glucose metabolism disease 9.9 TNF TLR9 IL6 IL1B CRP
363 acquired metabolic disease 9.9 TNF TLR9 IL6 IL1B CRP
364 periapical periodontitis 9.9 TNF TLR2 MMP8 IL6 IL1B
365 mycoplasma pneumoniae pneumonia 9.9 TNF TLR2 IL6 IL10 CRP
366 prostatitis 9.9 TNF IL6 IL1B IL10 CXCL8
367 mycetoma 9.9 MMP9 IL10 CXCL8 CR1
368 contact dermatitis 9.9 TNF IL6 IL1B IL10 CXCL8
369 autoimmune disease of musculoskeletal system 9.9 TNF TLR9 IL6 IL10 CRP
370 glomerulonephritis 9.9 TLR9 IL1B CR1 CFP
371 creutzfeldt-jakob disease 9.9
372 crouzon syndrome 9.9
373 intussusception 9.9
374 varicose veins 9.9
375 chordoma 9.9
376 immune deficiency disease 9.9
377 pituitary adenoma, prolactin-secreting 9.9
378 polysubstance abuse 9.9
379 nasopharyngeal carcinoma 9.9
380 cyanosis, transient neonatal 9.9
381 mulchandani-bhoj-conlin syndrome 9.9
382 metabolic acidosis 9.9
383 aphasia 9.9
384 ptosis 9.9
385 myelomeningocele 9.9
386 thrombosis 9.9
387 chronic meningitis 9.9
388 sphenoid sinusitis 9.9
389 esophageal varix 9.9
390 lemierre's syndrome 9.9
391 hemopericardium 9.9
392 protein-energy malnutrition 9.9
393 cortical blindness 9.9
394 uveitis 9.9
395 facial paralysis 9.9
396 papilledema 9.9
397 dental caries 9.9
398 dermoid cyst 9.9
399 cystic teratoma 9.9
400 substance abuse 9.9
401 acute kidney failure 9.9
402 ischemia 9.9
403 intracranial thrombosis 9.9
404 hyperglycemia 9.9
405 rhinitis 9.9
406 poliomyelitis 9.9
407 mature teratoma 9.9
408 kidney disease 9.9
409 complement deficiency 9.9
410 myocarditis 9.9
411 epiglottitis 9.9
412 herpes simplex encephalitis 9.9
413 aneurysm 9.9
414 chronic pain 9.9
415 neurenteric cyst 9.9
416 synovitis 9.9 TNF IL6 IL1B CXCL8 CRP
417 leishmaniasis 9.9 TNF TLR9 TLR4 TLR2 IL1B IL10
418 noonan syndrome 1 9.9 TNF IL6 IL1B CXCL8
419 endometriosis 9.8 IL6 IL1B CXCL8
420 funisitis 9.8 MMP8 IL6 IL1B IL10 CXCL8
421 human immunodeficiency virus infectious disease 9.8 TNF TLR9 S100B IL6 IL10
422 idiopathic neutropenia 9.8 TNF TLR4 IL6 IL1B IL10
423 rosacea 9.8 TNF TLR2 MMP9 MMP8 IL6
424 female reproductive system disease 9.8 TNF TLR9 MMP9 IL6 CXCL8
425 reproductive system disease 9.8 TNF TLR9 MMP9 IL6 CXCL8
426 visceral leishmaniasis 9.8 TNF TLR9 TLR4 TLR2 IL10 CXCL8
427 paracoccidioidomycosis 9.8 TNF TLR4 TLR2 IL6 IL10
428 echinococcosis 9.8 TNF TLR4 TLR2 IL6 IL10
429 melioidosis 9.8 TNF TLR4 TLR2 IL6 IL10
430 typhoid fever 9.8 TNF TLR4 IL6 IL1B CRP
431 endometrial disease 9.8 TNF TLR4 IL6 IL1B CXCL8
432 juvenile ankylosing spondylitis 9.8 TNF IL6
433 viral pneumonia 9.7 TLR9 IL6 CRP CR1
434 cystitis 9.7 TNF TLR4 IL6 CXCL8 CRP
435 parasitic protozoa infectious disease 9.7 TNF TLR9 TLR2 IL6 IL1B IL10
436 aortic valve disease 1 9.7
437 coronary artery dissection, spontaneous 9.7
438 hand skill, relative 9.7
439 attention deficit-hyperactivity disorder 9.7
440 hypertriglyceridemia, familial 9.7
441 migraine with or without aura 1 9.7
442 myositis 9.7
443 retinal detachment 9.7
444 syringomyelia, noncommunicating isolated 9.7
445 thrombophilia due to thrombin defect 9.7
446 vitreoretinopathy, neovascular inflammatory 9.7
447 complement component 2 deficiency 9.7
448 l-2-hydroxyglutaric aciduria 9.7
449 pituitary hormone deficiency, combined, 2 9.7
450 hypothyroidism, congenital, nongoitrous, 4 9.7
451 aging 9.7
452 kearns-sayre syndrome 9.7
453 stroke, ischemic 9.7
454 brittle bone disorder 9.7
455 sickle cell anemia 9.7
456 langerhans cell histiocytosis 9.7
457 aneurysmal bone cysts 9.7
458 allergic rhinitis 9.7
459 resting heart rate, variation in 9.7
460 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 9.7
461 complement component 7 deficiency 9.7
462 mannose-binding lectin deficiency 9.7
463 complement component 4a deficiency 9.7
464 leukemia, acute lymphoblastic 3 9.7
465 hyperprolactinemia 9.7
466 spastic paraplegia, intellectual disability, nystagmus, and obesity 9.7
467 deficiency anemia 9.7
468 rocky mountain spotted fever 9.7
469 aspiration pneumonia 9.7
470 tick-borne encephalitis 9.7
471 erythema multiforme 9.7
472 foodborne botulism 9.7
473 2-hydroxyglutaric aciduria 9.7
474 withdrawal disorder 9.7
475 adenoid hypertrophy 9.7
476 purpura fulminans 9.7
477 bone disease 9.7
478 fibrous dysplasia 9.7
479 mumps 9.7
480 petrositis 9.7
481 frontal sinusitis 9.7
482 chronic maxillary sinusitis 9.7
483 japanese encephalitis 9.7
484 cholesteatoma of middle ear 9.7
485 discitis 9.7
486 spotted fever 9.7
487 hypoparathyroidism 9.7
488 orbital cellulitis 9.7
489 diphtheria 9.7
490 horner's syndrome 9.7
491 dental pulp necrosis 9.7
492 inflammatory spondylopathy 9.7
493 bronchopneumonia 9.7
494 dysentery 9.7
495 hepatic coma 9.7
496 dementia 9.7
497 periventricular leukomalacia 9.7
498 klebsiella pneumonia 9.7
499 hepatic encephalopathy 9.7
500 purulent labyrinthitis 9.7
501 patent foramen ovale 9.7
502 panophthalmitis 9.7
503 sick sinus syndrome 9.7
504 polyneuropathy 9.7
505 chronic purulent otitis media 9.7
506 acute cholangitis 9.7
507 pyuria 9.7
508 hypothyroidism 9.7
509 epilepsy 9.7
510 maxillary sinusitis 9.7
511 constipation 9.7
512 vulvovaginitis 9.7
513 splenic infarction 9.7
514 relapsing polychondritis 9.7
515 agammaglobulinemia 9.7
516 hemoglobinopathy 9.7
517 cystic kidney disease 9.7
518 glioblastoma multiforme 9.7
519 astrocytoma 9.7
520 cystadenocarcinoma 9.7
521 chronic granulomatous disease 9.7
522 syringomyelia 9.7
523 histiocytosis 9.7
524 cellulitis 9.7
525 bile duct cystadenocarcinoma 9.7
526 heart valve disease 9.7
527 liver disease 9.7
528 hypokalemia 9.7
529 ludwig's angina 9.7
530 movement disease 9.7
531 adenosquamous carcinoma 9.7
532 benign ependymoma 9.7
533 pituitary gland disease 9.7
534 functioning pituitary adenoma 9.7
535 inferior myocardial infarction 9.7
536 congestive heart failure 9.7
537 conjunctivitis 9.7
538 acute disseminated encephalomyelitis 9.7
539 inherited metabolic disorder 9.7
540 spinal stenosis 9.7
541 chronic kidney disease 9.7
542 ileus 9.7
543 paralytic ileus 9.7
544 influenza 9.7
545 bullous pemphigoid 9.7
546 herpes zoster 9.7
547 neuromyelitis optica 9.7
548 learning disability 9.7
549 pemphigus 9.7
550 homocystinuria 9.7
551 iridocyclitis 9.7
552 diabetes insipidus 9.7
553 ethmoid sinusitis 9.7
554 bacterial conjunctivitis 9.7
555 hypereosinophilic syndrome 9.7
556 microcephaly 9.7
557 col1a1/2-related osteogenesis imperfecta 9.7
558 congenital disorders of n-linked glycosylation and multiple pathway 9.7
559 sickle cell disease 9.7
560 anterior uveitis 9.7
561 athetosis 9.7
562 autoimmune encephalitis 9.7
563 brca2 hereditary breast and ovarian cancer syndrome 9.7
564 chromosomal triplication 9.7
565 complement component deficiency 9.7
566 congenital extrahepatic portosystemic shunt 9.7
567 ependymoma 9.7
568 glioblastoma 9.7
569 granulocytopenia 9.7
570 hhv-6 encephalitis 9.7
571 idiopathic hypertrophic pachymeningitis 9.7
572 immunoglobulin g deficiency 9.7
573 lymphatic malformations 9.7
574 meningococcemia 9.7
575 pineal cyst 9.7
576 primary agammaglobulinemia 9.7
577 splenomegaly 9.7
578 tethered cord syndrome 9.7
579 cerebral atrophy 9.7
580 myoclonus 9.7
581 spinal cord infarction 9.7
582 rapidly involuting congenital hemangioma 9.7
583 nasal encephalocele 9.7
584 basal encephalocele 9.7
585 spina bifida cystica 9.7
586 igg4-related pachymeningitis 9.7
587 cerebral visual impairment 9.7
588 non-functioning pituitary adenoma 9.7
589 vitreoretinopathy 9.7
590 castleman disease 9.7 IL6 IL10 CRP CR1
591 pulmonary edema 9.7 TNF PIK3C2A IL1B IL10 CXCL8 CRP
592 lymph node disease 9.7 TNF TLR9 IL6 IL1B IL10 CRP
593 upper respiratory tract disease 9.7 TNF TLR9 IL6 IL1B IL10 CXCL8
594 bronchial disease 9.7 TNF TLR9 IL6 IL1B IL10 CXCL8
595 muscular disease 9.7 TNF TLR9 PIK3C2A IL6 CRP
596 arteriosclerosis 9.7 TLR4 MMP9 IL6 IL10 CRP
597 arteries, anomalies of 9.6 TNF TLR9 MMP9 IL6 IL1B CRP
598 q fever 9.6 TNF TLR4 TLR2 IL6 IL1B IL10
599 interstitial lung disease 9.6 TNF MMP9 IL6 IL1B IL10 CXCL8
600 filariasis 9.6 TNF TLR9 TLR4 TLR2 IL6 IL10
601 bacterial vaginosis 9.6 TNF TLR4 TLR2 IL6 IL1B CXCL8
602 pulmonary disease, chronic obstructive 9.6 TNF TLR2 MMP9 IL6 CXCL8 CRP
603 esophageal cancer 9.5 TNF MMP9 IL6 CXCL8 CRP
604 bronchiolitis obliterans 9.5 TNF MMP9 MMP8 IL6 IL10 CXCL8
605 dilated cardiomyopathy 9.5 TNF MMP9 IL6 IL1B IL10 CRP
606 preterm premature rupture of the membranes 9.5 MMP9 MMP8 IL6 IL1B CXCL8 CRP
607 ewing sarcoma 9.5 TNF S100B MMP9 IL6 IL1B
608 trypanosomiasis 9.5 TNF TLR9 TLR2 IL6 IL1B IL10
609 acute myocardial infarction 9.5 PIK3C2A MMP9 CRP CKB
610 bone inflammation disease 9.4 TNF TLR9 IL6 IL1B IL10 CXCL8
611 toxoplasmosis 9.4 TNF TLR9 TLR4 TLR2 IL6 IL1B
612 gingivitis 9.4 TNF TLR2 MMP9 MMP8 IL6 IL1B
613 chagas disease 9.3 TNF TLR4 TLR2 IL6 IL1B IL10
614 colitis 9.3 TNF TLR9 TLR4 IL6 IL1B IL10
615 asthma 9.3 TNF TLR9 MMP9 IL6 IL1B IL10
616 perinatal necrotizing enterocolitis 9.3 TNF TLR9 TLR4 IL6 IL1B CXCL8
617 legionellosis 9.3 TNF TLR4 TLR2 PIK3C2A IL1B CR1
618 ulcerative colitis 9.3 TNF TLR4 IL6 IL1B IL10 CXCL8
619 bronchiolitis 9.3 TNF TLR9 TLR4 IL6 IL10 CXCL8
620 aggressive periodontitis 9.3 TNF TLR4 MMP8 IL6 IL1B IL10
621 large intestine cancer 9.1 TNF TLR9 MMP9 IL6 IL1B IL10
622 cardiac arrest 9.1 S100B PIK3C2A CKB
623 chlamydia 9.1 TNF TLR4 TLR2 IL6 IL1B IL10
624 inflammatory bowel disease 9.1 TNF TLR4 TLR2 IL6 IL1B IL10
625 intestinal disease 9.1 TNF TLR9 TLR4 IL6 IL1B IL10
626 appendicitis 9.1 TNF MMP9 MMP8 IL6 IL1B IL10
627 behcet syndrome 9.1 TNF TLR9 TLR4 IL6 IL1B IL10
628 mouth disease 9.1 TNF TLR9 TLR4 MMP8 IL6 IL1B
629 leptospirosis 9.0 TNF TLR2 PIK3C2A IL6 IL1B IL10
630 chorioamnionitis 9.0 TNF TLR4 MMP9 MMP8 IL6 IL1B
631 extrinsic cardiomyopathy 8.9 TNF TLR9 TLR4 PIK3C2A IL6 IL1B
632 heart disease 8.9 TNF S100B PIK3C2A IL6 IL1B IL10
633 primary bacterial infectious disease 8.9 TNF TLR9 TLR4 TLR2 IL6 IL1B
634 gastrointestinal system disease 8.8 TNF TLR9 TLR4 MMP9 IL6 IL1B
635 respiratory system disease 8.8 TNF TLR9 TLR4 MMP9 IL6 IL1B
636 rheumatoid arthritis 8.8 TNF TLR4 TLR2 MMP9 IL6 IL1B
637 periodontitis 8.3 TNF TLR9 TLR4 TLR2 MMP9 MMP8
638 myocardial infarction 7.7 TNF TLR4 S100B PIK3C2A MMP9 IL6

Comorbidity relations with Bacterial Meningitis via Phenotypic Disease Network (PDN): (showing 1, show less)


Acute Cystitis

Graphical network of the top 20 diseases related to Bacterial Meningitis:



Diseases related to Bacterial Meningitis

Symptoms & Phenotypes for Bacterial Meningitis

MGI Mouse Phenotypes related to Bacterial Meningitis:

46 (showing 10, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.21 CFP CRP IL10 IL1B IL6 MMP8
2 cardiovascular system MP:0005385 10.16 CFP CRP IL10 IL1B IL6 MMP9
3 behavior/neurological MP:0005386 10.13 CKB IL10 IL6 MMP9 PTGDS S100B
4 immune system MP:0005387 10.13 CFP CRP IL10 IL1B IL6 MMP8
5 hematopoietic system MP:0005397 10.1 IL10 IL1B IL6 MMP9 PIK3C2A PTGDS
6 digestive/alimentary MP:0005381 9.98 IL10 IL6 MMP9 TLR2 TLR4 TLR9
7 integument MP:0010771 9.91 IL10 IL1B IL6 MMP9 PTGDS S100B
8 neoplasm MP:0002006 9.81 IL10 IL1B IL6 MMP8 MMP9 PTGDS
9 nervous system MP:0003631 9.61 CKB IL10 IL1B IL6 MMP9 PTGDS
10 skeleton MP:0005390 9.28 CFP IL10 IL1B IL6 MMP9 PTGDS

Drugs & Therapeutics for Bacterial Meningitis

Drugs for Bacterial Meningitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 148, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Phenytoin Approved, Vet_approved Phase 4 57-41-0 1775
2
Acetaminophen Approved Phase 4 103-90-2 1983
3
Cefoxitin Approved Phase 4 35607-66-0 441199
4
Cefotaxime Approved Phase 4 63527-52-6 456256 5742673
5
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
6
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
7
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
8
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
9
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
10
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4 1177-87-3
11
Azathioprine Approved Phase 4 446-86-6 2265
12
Prednisolone hemisuccinate Experimental Phase 4 2920-86-7
13 Diuretics, Potassium Sparing Phase 4
14 Anticonvulsants Phase 4
15 Sodium Channel Blockers Phase 4
16 Cytochrome P-450 Enzyme Inducers Phase 4
17 Vaccines Phase 4
18 Immunologic Factors Phase 4
19 Analgesics, Non-Narcotic Phase 4
20 Analgesics Phase 4
21 Peripheral Nervous System Agents Phase 4
22 Lactams Phase 4
23 Antipyretics Phase 4
24 beta-Lactams Phase 4
25 Heptavalent Pneumococcal Conjugate Vaccine Phase 4
26 penicillins Phase 4
27 Gentamicins Phase 4
28 Protective Agents Phase 4
29 Hormones Phase 4
30 Prednisolone acetate Phase 4
31 Neuroprotective Agents Phase 4
32 glucocorticoids Phase 4
33 Antiemetics Phase 4
34 Methylprednisolone Acetate Phase 4
35 Hormone Antagonists Phase 4
36 Anti-Inflammatory Agents Phase 4
37 Autonomic Agents Phase 4
38 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
39 Antibodies Phase 4
40 Immunoglobulins Phase 4
41 HIV Protease Inhibitors Phase 4
42
protease inhibitors Phase 4
43 Antineoplastic Agents, Hormonal Phase 4
44 BB 1101 Phase 4
45 Immunosuppressive Agents Phase 4
46 Antimetabolites Phase 4
47 Antimetabolites, Antineoplastic Phase 4
48 Antirheumatic Agents Phase 4
49 Neuromuscular Blocking Agents Phase 4
50 Pharmaceutical Solutions Phase 2, Phase 3
51 Rho(D) Immune Globulin Phase 3
52 gamma-Globulins Phase 3
53 Immunoglobulins, Intravenous Phase 3
54
Fluconazole Approved, Investigational Phase 2 86386-73-4 3365
55
Amphotericin B Approved, Investigational Phase 2 1397-89-3 14956 5280965
56
Miconazole Approved, Investigational, Vet_approved Phase 2 22916-47-8 4189
57
Meropenem Approved, Investigational Phase 1, Phase 2 119478-56-7, 96036-03-2 64778 441130
58
Clavulanate Approved, Vet_approved Phase 2 58001-44-8 5280980
59
Amoxicillin Approved, Vet_approved Phase 2 26787-78-0 33613
60
Histamine Approved, Investigational Phase 2 51-45-6 774
61
Sodium citrate Approved, Investigational Phase 2 68-04-2
62
Ranitidine Approved Phase 2 66357-35-5, 66357-59-3 3001055
63
Ceftobiprole Approved, Investigational Phase 2 209467-52-7 6918430
64
Citric acid Approved, Nutraceutical, Vet_approved Phase 2 77-92-9 311
65
Ceftobiprole medocaril Experimental, Investigational Phase 2 376653-43-9
66 Cytochrome P-450 Enzyme Inhibitors Phase 2
67 beta-Lactamase Inhibitors Phase 2
68 14-alpha Demethylase Inhibitors Phase 2
69 Cytochrome P-450 CYP2C9 Inhibitors Phase 2
70 Antifungal Agents Phase 2
71 Liposomal amphotericin B Phase 2
72 Steroid Synthesis Inhibitors Phase 2
73 Cytochrome P-450 CYP2C19 Inhibitors Phase 2
74 Antiparasitic Agents Phase 2
75 Antiprotozoal Agents Phase 2
76 Neurotransmitter Agents Phase 2
77 Citrate Phase 2
78 Amoxicillin-Potassium Clavulanate Combination Phase 2
79 Antacids Phase 2
80
Histamine Phosphate Phase 2 51-74-1 65513
81 Histamine Antagonists Phase 2
82 Anti-Ulcer Agents Phase 2
83 Bismuth tripotassium dicitrate Phase 2
84 Histamine H2 Antagonists Phase 2
85
Bismuth Phase 2 7440-69-9 16682734 105143
86 Ranitidine bismuth citrate Phase 2
87 Cephalosporins Phase 2
88
Ceftriaxone Approved Phase 1 73384-59-5 5479530 5361919
89
Daptomycin Approved, Investigational Phase 1 103060-53-3 16129629
90
Fosfomycin Approved 23155-02-4 446987
91
Glycerol Approved, Investigational Early Phase 1 56-81-5 753
92
Ciprofloxacin Approved, Investigational Early Phase 1 85721-33-1 2764
93
Oxycodone Approved, Illicit, Investigational 76-42-6 5284603
94
Alfentanil Approved, Illicit 71195-58-9 51263
95
Tazobactam Approved 89786-04-9 123630
96
Cidofovir Approved 113852-37-2 60613
97
Tranexamic Acid Approved 1197-18-8 5526
98
Molindone Approved 7416-34-4 23897
99
Cefepime Approved, Investigational 88040-23-7 5479537
100
Nifedipine Approved 21829-25-4 4485