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MCID: BCT004
MIFTS: 48

Bacteriuria

Categories: Nephrological diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Bacteriuria

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MalaCards integrated aliases for Bacteriuria:

Name: Bacteriuria 12 55 44 15 72

Classifications:

MalaCards categories:
Anatomical: Nephrological diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:1412
MeSH 44 D001437
SNOMED-CT 68 61373006
ICD10 33 R82.71
UMLS 72 C0004659
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Summaries for Bacteriuria

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Disease Ontology : 12 A urinary system disease which consists of the presence of bacteria in urine.

MalaCards based summary : Bacteriuria is related to acute cystitis and acute pyelonephritis. An important gene associated with Bacteriuria is CXCL8 (C-X-C Motif Chemokine Ligand 8), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs acetic acid and Tacrolimus have been mentioned in the context of this disorder. Affiliated tissues include testes, prostate and spinal cord, and related phenotypes are hematopoietic system and cardiovascular system

Wikipedia : 75 Bacteriuria is the presence of bacteria in urine. Bacteriuria accompanied by symptoms is a urinary tract... more...

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Related Diseases for Bacteriuria

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Diseases related to Bacteriuria via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 299)
# Related Disease Score Top Affiliating Genes
1 acute cystitis 32.0 IL6 CXCL8 CCL2
2 acute pyelonephritis 31.6 IL6 CXCR1 CXCL8
3 cystitis 31.1 TLR4 IL6 CXCL8 CCL2
4 pyelonephritis 31.1 TLR4 IL6 CXCR1 CXCL8 CCL2
5 prosthetic joint infection 30.6 TLR4 TLR2
6 typhoid fever 30.3 TLR5 TLR4 IL6
7 vaginitis 30.3 PRF1 IL6 CXCL8
8 endocarditis 30.1 TLR2 IL6 CXCL8
9 chorioamnionitis 30.1 TLR4 IL6 CXCL8 CCL2
10 cytomegalovirus infection 30.0 IL6 CXCL8 CCL2
11 pyelitis 29.9 TLR4 IL6 CXCR1 CXCL8
12 iga glomerulonephritis 29.9 IL6 CD40LG CCL2
13 toxic shock syndrome 29.5 TLR4 TLR2 IL6 CXCL8
14 mastitis 29.5 TLR2 IL6 CXCL8
15 chlamydia 29.4 TLR4 TLR2 IL6 CXCL8
16 peritonitis 28.9 TLR2 IL6 CXCL8 CCL2
17 bacterial infectious disease 28.3 TLR5 TLR4 TLR2 TLR1 IL6 CXCL8
18 systemic lupus erythematosus 28.2 TLR5 TLR4 TLR2 IL6 CD40LG CCL2
19 rheumatoid arthritis 27.3 TLR4 TLR2 IL6 CXCL8 CD40LG CCL2
20 urethral syndrome 11.6
21 urachal cancer 11.2
22 pyuria 10.9
23 spinal cord injury 10.6
24 pouchitis 10.6 TLR4 CXCL8
25 recurrent corneal erosion 10.6 IL6 CXCL8
26 bagassosis 10.6 IL6 CXCL8
27 superficial urinary bladder cancer 10.6 TLR4 CXCL8
28 streptococcal toxic-shock syndrome 10.6 IL6 CXCL8
29 acute transverse myelitis 10.6 IL6 CXCL8
30 transverse myelitis 10.6 IL6 CXCL8
31 papillary conjunctivitis 10.6 IL6 CXCL8
32 funisitis 10.6 IL6 CXCL8
33 neurogenic bladder 10.6
34 periodontosis 10.5 TLR4 CXCL8
35 acute monoblastic leukemia 10.5 IL6 CXCL8
36 diabetes mellitus 10.5
37 capillary leak syndrome 10.5 IL6 CXCL8
38 meconium aspiration syndrome 10.5 IL6 CXCL8
39 louse-borne relapsing fever 10.5 IL6 CXCL8
40 chronic pyelonephritis 10.5
41 herpes simplex virus keratitis 10.5 CXCL8 CCL2
42 necrotizing fasciitis 10.5 IL6 CXCL8
43 cystic echinococcosis 10.5 TLR4 IL6
44 endocervicitis 10.5 TLR4 CCL2
45 israeli tick typhus 10.4 CXCL8 CCL2
46 intussusception 10.4 IL6 CD40LG
47 cysticercosis 10.4 TLR4 IL6
48 endometrial disease 10.4 TLR4 IL6 CXCL8
49 perinatal necrotizing enterocolitis 10.4 TLR4 IL6 CXCL8
50 colitis 10.4 TLR4 IL6 CXCL8

Graphical network of the top 20 diseases related to Bacteriuria:



Diseases related to Bacteriuria
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Symptoms & Phenotypes for Bacteriuria

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MGI Mouse Phenotypes related to Bacteriuria:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.81 CD40LG CXCR1 IL6 PRF1 TIRAP TLR1
2 cardiovascular system MP:0005385 9.8 CD40LG IL6 PRF1 TIRAP TLR2 TLR4
3 immune system MP:0005387 9.65 CCL2 CD40LG CXCR1 IL6 PRF1 TIRAP
4 neoplasm MP:0002006 9.02 CAT IL6 PRF1 TLR2 TLR4
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Drugs & Therapeutics for Bacteriuria

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Drugs for Bacteriuria (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 117)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
acetic acid Approved Phase 4 64-19-7 176
2
Tacrolimus Approved, Investigational Phase 4 104987-11-3 445643 439492 6473866
3
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
4
Sirolimus Approved, Investigational Phase 4 53123-88-9 6436030 5284616 46835353
5
Mycophenolic acid Approved Phase 4 24280-93-1 446541
6
Everolimus Approved Phase 4 159351-69-6 6442177 70789204
7
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
8
Fosfomycin Approved Phase 4 23155-02-4 446987
9
Nitrofurantoin Approved, Vet_approved Phase 4 67-20-9 5353830
10
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
11
Iodine Approved, Investigational Phase 4 7553-56-2 807
12
Povidone Approved Phase 4 9003-39-8
13
Povidone-iodine Approved Phase 4 25655-41-8
14 Disinfectants Phase 4
15 Chlorhexidine gluconate Phase 4
16 Dermatologic Agents Phase 4
17 Gentamicins Phase 4
18
Retinol acetate Phase 4 127-47-9 10245972
19 Antifungal Agents Phase 4
20 Immunologic Factors Phase 4
21 Immunosuppressive Agents Phase 4
22 Calcineurin Inhibitors Phase 4
23 Renal Agents Phase 4
24 Anti-Infective Agents, Urinary Phase 4
25 Pharmaceutical Solutions Phase 4
26 Anti-Infective Agents, Local Phase 4
27 Micronutrients Phase 4
28 Nutrients Phase 4
29 Plasma Substitutes Phase 4
30 cadexomer iodine Phase 4
31 Blood Substitutes Phase 4
32 Trace Elements Phase 4
33
Ofloxacin Approved Phase 3 82419-36-1 4583
34
Levofloxacin Approved, Investigational Phase 3 100986-85-4 149096
35
Lomefloxacin Approved, Investigational Phase 3 98079-51-7 3948
36
Ciprofloxacin Approved, Investigational Phase 3 85721-33-1 2764
37
Cefazolin Approved Phase 3 25953-19-9 656510 33255
38 Proanthocyanidin Phase 3
39 Antioxidants Phase 3
40
Procyanidin Phase 3 4852-22-6 147299
41 Protective Agents Phase 3
42 Anthocyanidin Phase 3
43 Anti-Infective Agents Phase 3
44 Antitubercular Agents Phase 3
45 Topoisomerase Inhibitors Phase 3
46 Cytochrome P-450 Enzyme Inhibitors Phase 3
47 Cytochrome P-450 CYP1A2 Inhibitors Phase 3
48 Cranberry Approved, Investigational Phase 2
49
Cephalexin Approved, Investigational, Vet_approved Phase 2 15686-71-2 27447
50
Trimethoprim Approved, Vet_approved Phase 2 738-70-5 5578

Interventional clinical trials:

(show top 50) (show all 106)
# Name Status NCT ID Phase Drugs
1 The Impact of Antimicrobial Treatment for Asymptomatic Bacteriuria in Renal Transplant Patients Unknown status NCT02113774 Phase 4
2 Comparison of the Effect of Applying Povidone-iodine and Chlorhexidine Solutions for Perinea Washing on Bacteriuria Rate and Type in Patients With Urinary Catheter in Intensive Care Unit Unknown status NCT02032394 Phase 4 Povidone-iodine;Chlorhexidine;Normal saline
3 Clinical Impact of Bacteriuria on Chronic Inflammation in Asymptomatic Hemodialysis Patients Unknown status NCT01570556 Phase 4
4 Pilot Study to Evaluate the Efficacy of Antiseptic Bladder Lavage Versus Pulsatile Lavage With Physiologic Serum in Catheterized Patients With Asymptomatic Bacteriuria With Uropathogens. Unknown status NCT01772875 Phase 4
5 Randomized Placebo-Controlled Trial of Gentamicin Bladder Instillation for the Prevention of Urinary Tract Infection in Adults at High Risk for Cystitis Due to Intermittent Catheterization Unknown status NCT01884467 Phase 4 Gentamicin;Placebo
6 Evaluation of Suprapubic Noble Metal Alloy BIP Foley Catheter in the Prevention of Catheter-associated Urinary Tract Infections in Spinal Cord Injured Patients Unknown status NCT02808000 Phase 4
7 Efficacy and Safety of Certican® in Combination With Myfortic® in Adult Renal Allograft Recipients Following Calcineurin Inhibitor Withdrawal at Week 16 Compared to Patients Who Are Maintained on Tacrolimus and Myfortic® Unknown status NCT01399242 Phase 4 Certican
8 The Bacteriuria in Renal Transplantation (BiRT) Study: A Prospective, Randomized, Parallel-group, Multicenter, Open-label, Superiority Trial Comparing Antibiotics Versus no Treatment in the Prevention of Symptomatic Urinary Tract Infection in Kidney Transplant Recipients With Asymptomatic Bacteriuria Completed NCT01871753 Phase 4
9 Use of Antibiotic Prophylaxis on Urethral Catheter Withdrawal: A Randomized Double-Blind Placebo-Controlled Trial Completed NCT00126698 Phase 4 trimethoprim-sulfamethoxazole;ciprofloxacin
10 Randomized Controlled Clinical Trial of Efficacy of Fosfomycin Versus Ciprofloxacin as Antibiotic Prophylaxis Prior to Ultrasound Guided Transrectal Prostate Biopsy Completed NCT01803191 Phase 4 Fosfomycin 3 g;Ciprofloxacin 500 mg
11 Perioperative Disodium Fosfomycin in the Prophylaxis of Urinary Tract Infection in Kidney Transplant Recipients. Controlled Clinical Trial (PERIFOS Trial) Completed NCT03235947 Phase 4 Fosfomycin disodium;Trimethoprim / Sulfamethoxazole;Intravenous placebo
12 Antibiotic Treatment for Intermittent Bladder Catheterisation: A Randomised Controlled Trial of Once Daily Prophylaxis Completed NCT02145338 Phase 4 Nitrofurantoin or Trimethoprim or Cefalexin
13 Fosfomycin-Trometamol in Urinary Tract Infection Prophylaxis After Kidney Transplantation. Randomized Controlled Trial. Completed NCT01820897 Phase 4 Fosfomycin-Trometamol;Sulfamethoxazole trimethoprim
14 Nitrofurantoin Administration for the Prevention of Short-Term Catheter Associated Urinary Tract Infection After Pelvic Surgery (NAUTICA): A Randomized Controlled Trial Completed NCT03287089 Phase 4 Nitrofurantoin 100 MG;Placebo Oral Tablet
15 Management of Sub-Clinical Bacteriuria in Pregnancy: A Feasibility Trial Recruiting NCT03275623 Phase 4 Antibiotic
16 A Randomized Trial of Betadine Bladder Irrigations vs. Standard of Care Prior to Indwelling Catheter Removal to Reduce Bacteriuria and Catheter-Associated Urinary Tract Infections Terminated NCT03447639 Phase 4 Povidone-iodine irrigation
17 Catheter Associated Urinary Tract Infections Unknown status NCT00446732 Phase 2, Phase 3
18 A Randomized, Controlled Trial of Cranberry Capsules for UTI Prevention in Nursing Home Residents Completed NCT01691430 Phase 3
19 A Multicenter, Randomized Study To Compare The Safety And Efficacy Of Oral Levofloxacin With That Of Lomefloxacin HCl In The Treatment Of Complicated Urinary Tract Infections In Adults Completed NCT00258102 Phase 3 Levofloxacin
20 A Multicenter, Double-Blind, Randomized Study To Compare The Safety And Efficacy Of Oral Levofloxacin With That Of Ciprofloxacin HCl In The Treatment Of Complicated Urinary Tract Infections In Adults Completed NCT00258089 Phase 3 Levofloxacin
21 Recurrent Urinary Tract Infections in Adult Women: a Pilot Study With Oral D Mannose Completed NCT01808755 Phase 3 trimethoprim/sulfamethoxazole
22 Antibiotic Prophylaxis for HDR Brachytherapy in the Treatment of Prostate Cancer: a Phase III Randomized Trial Recruiting NCT03862170 Phase 3 Ciprofloxacin;Cefazolin
23 Prevention of Recurrent Symptomatic Urinary Tract Infections in Participants With Chronic Neurogenic Bladder Dysfunction: A Mixed Method Study Unknown status NCT02591901 Phase 2 Uro vaxom
24 A Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Effect of Adjuvant Treatment With Compound Cranberry Extract Tablets (UmayC) in Acute Bacterial Cystitis. Unknown status NCT00305071 Phase 2 compound cranberry extract tablet
25 A Pilot Randomized Control Study of Shortening Antibiotic Treatment Duration For Asymptomatic Bacteriuria Within A Month After Kidney Transplantation Completed NCT02575495 Phase 2 7 days course of antibiotic treatment;14 days course of antibiotic treatment
26 A Phase IIa Open Label Study to Evaluate the Safety and Antimicrobial Effects of NVC-422 on Bacteriuria in Chronically Catheterized Subjects Completed NCT00781339 Phase 2 sodium 2-(dichloroamino)-2-methylpropane-1-sulfonate monohydrate
27 Prevention of Nosocomial Escherichia Coli Infections After Placement of an Indwelling Catheter During Pelvic Surgery: a Randomized, Prospective, Double Blind Study for the Evaluation of Cranberry (Vaccinium Macrocarpon) Gel Capsules Completed NCT01114347 Phase 2
28 Methenamine Hippurate With Cranberry Capsules Versus Cranberry Capsules Alone for UTI Prevention in a Short-term Indwelling Foley Catheter Population After Urogynecological Surgery: A Double-Blinded Randomized Controlled Trial Recruiting NCT03818321 Phase 2 Methenamine Hippurate 1 g tablet;Placebo tablet
29 Empirical Use of Fosfomycin as a Single Dose Oral Treatment of Asymptomatic Bacteriuria Active, not recruiting NCT03548129 Phase 2 phosphomycin;Culture specific antibiotic therapy
30 Targeted Clinical Trials to Reduce the Risk of Antimicrobial Resistance The SCOUT Study: "Short Course Therapy for Urinary Tract Infections in Children" Active, not recruiting NCT01595529 Phase 2 Cefixime;Cephalexin;Trimethoprim/Sulfamethoxazole
31 New Prognostic Classification of Acute Pyelonephritis With Adaptation of the Therapeutic. Prospective Randomized Study in the Emergency Terminated NCT01628900 Phase 2
32 H-23187: Probiotic Prophylaxis Against Recurrent Pediatric Urinary Tract Infection Withdrawn NCT00789464 Phase 2 trimethoprim/sulfamethoxazole
33 Probiotics Improvement of Gastrointestinal and Genitourinary Health in Girls With Spina Bifida (H-23245) Withdrawn NCT00767988 Phase 2
34 Bacteriuria Eradication Through Probiotics Unknown status NCT00717600 Phase 1
35 Pilot Study: Dosing Study of Cranberry Capsules for the Prevention of Bacteriuria in Nursing Home Residents Completed NCT01033383 Phase 1
36 Cranberry for Prevention of Bacteriuria in Pregnancy Completed NCT00093938 Phase 1 Cranberry juice
37 Prospective, Phase I, Single-Center, Evaluation of the Safety and Tolerability of Nitric Oxide Impregnated Urinary Catheters in Patients Undergoing Radical Prostatectomy Completed NCT02277171 Phase 1
38 Evaluate the Safety in Human Subjects of Using Bladder Catheters That Are Pre-Coated With a Biofilm That Contains Living Bacteria Escherichia Coli 83972. Completed NCT00458471 Phase 1
39 Bacterial Interference for Prevention of Catheter-Associated UTI Completed NCT00554996 Phase 1
40 Tissue Bonding Cystostomy(TBC) Not yet recruiting NCT01771159 Phase 1
41 Retained Urine Volume and Bacteriuria in Traditional Versus Vented Urine Drainage Systems Withdrawn NCT02052674 Phase 1
42 Antibiotic Treatment Versus no Therapy in Kidney Transplant Recipients With Asymptomatic Bacteriuria. A Prospective Randomized Study. Unknown status NCT01771432 Antibiotic treatment
43 Intraoperative One-Time Catheterization in Short Gynecologic Procedures and Its Potential Effect on Symptomatic and Asymptomatic Bacteriuria Unknown status NCT01926756
44 Asymptomatic Bacteriuria & Risk of Urinary Tract Infection in Renal Transplants Unknown status NCT01349738 Antibiotic
45 The Efficacy of Preventive Antibiotic Treatment During the Puerperium Among Pregnant Women With Recurrent Urinary Tract Infections Unknown status NCT01507974 Preventive antibiotic treatment- NITROFURANTOIN;Preventive antibiotic treatment- CEPHALEXIN;PREVENTIVE TREATMENT- AMOXICILLIN;PREVENTIVE TREATMENT- AMOXICILLIN AND CLAVULANATE POTASSIUM;PREVENTIVE TREATMENT- CEFUROXIME;PREVENTIVE TREATMENT SULFAMETHOXAZOLE AND TRIMETHOPRIM
46 Phase 3- Dexamethasone Administration in 1st Episode of Febrile Urinary Tract Infection Episode as Renal Damage Prevention Strategy. DEXCAR Unknown status NCT02034851
47 The Alternating Bidirectional Versus The Standard Approach During Shock Wave Lithotripsy For Renal And Upper Lumbar Ureteric Stones. A Randomized Clinical Trial Unknown status NCT03243682
48 Extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL) Vertical Transmission in Preterm Labor Unknown status NCT03251885
49 Post-operative Voiding Dysfunction: the Preferred Method for Catheterization Unknown status NCT01597544
50 Open Prospective Study on Reduction of Bacteriuria Following Bladder Irrigation With Chlorhexidine Completed NCT01782404

Search NIH Clinical Center for Bacteriuria

Inferred drug relations via UMLS 72 / NDF-RT 51 :


Methenamine
methenamine hippurate
methenamine mandelate
METHENAMINE SULFOSALICYLATE

Cochrane evidence based reviews: bacteriuria

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Genetic Tests for Bacteriuria

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Anatomical Context for Bacteriuria

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MalaCards organs/tissues related to Bacteriuria:

41
Testes, Prostate, Spinal Cord, Kidney, Colon, Neutrophil, Liver
Sources

Publications for Bacteriuria

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Articles related to Bacteriuria:

(show top 50) (show all 5739)
# Title Authors PMID Year
1
Comparison of urinary proteins in calcium stone formers and healthy individuals: a case-control study. 9 38
16493220 2006
2
Urinary Tamm-Horsfall protein and citrate: a case-control study of inhibitors and promoters of calcium stone formation. 9 38
17629875 2005
3
Group B streptococci cultured in urine during pregnancy associated with preterm delivery: a selection problem? 38
29595087 2019
4
Teamwork and safety climate affect antimicrobial stewardship for asymptomatic bacteriuria. 38
31339085 2019
5
Re: Association of Screening and Treatment for Preoperative Asymptomatic Bacteriuria with Postoperative Outcomes among US Veterans. 38
31169452 2019
6
The Incidence and Diagnostic Yield of Repeat Urine Culture in Hospitalized Patients: An Opportunity for Diagnostic Stewardship. 38
31391227 2019
7
Knowledge and Practices of Physicians and Nurses Related to Urine Cultures in Catheterized Patients: An Assessment of Adherence to IDSA Guidelines. 38
31375836 2019
8
High prevalence of carbapenamase genes, AmpC genes and aminoglycoside resistance genes in extended spectrum β-lactamase positive uropathogens from Northern India. 38
31398493 2019
9
Effectiveness of D-mannose, Hibiscus sabdariffa and Lactobacillus plantarum therapy in prevention of infectious events following urodynamic study. 38
30208764 2019
10
Is it possible to extrapolate the rates of resistance of Escherichia coli from asymptomatic bacteriuria in pregnant women to those of E. coli in uncomplicated community-acquired UTI? 38
31328907 2019
11
Impact of syndrome-specific antimicrobial stewardship interventions on use of and resistance to fluoroquinolones: An interrupted time series analysis. 38
30850252 2019
12
[Is it necessary to perform urine culture systematically prior to double J ureteral stent removal?] 38
31387836 2019
13
Sensitivity of point-of-care testing C reactive protein and procalcitonin to diagnose urinary tract infections in Dutch nursing homes: PROGRESS study protocol. 38
31401614 2019
14
Re: Reduced Recurrence of Low-Grade Papillary Bladder Tumors Associated with Asymptomatic Bacteriuria. 38
31385735 2019
15
Prevalence of bloodstream infections in neutropenic patients with bacteriuria. 38
31118114 2019
16
Pregnancy outcome following bacteriuria in pregnancy and the significance of nitrites in urinalysis - a retrospective cohort study. 38
31141487 2019
17
UTI patients have pre-existing antigen-specific antibody titers against UTI vaccine antigens. 38
31320216 2019
18
Role of patient descriptors in predicting antimicrobial resistance in urinary tract infections using a decision tree approach: A retrospective cohort study. 38
31128824 2019
19
Proliferation rate and penicillin binding of enterococcal isolates from patients with immunosupression. 38
30980551 2019
20
Long-term prescribing of nitrofurantoin for urinary tract infections (UTI) in veterans with spinal cord injury (SCI). 38
29985783 2019
21
Risk factors for group B streptococcus early-onset disease: an Italian, area-based, case-control study. 38
31170843 2019
22
Is Routine Urinary Screening Indicated Prior To Elective Total Joint Arthroplasty? A Systematic Review and Meta-Analysis. 38
30956050 2019
23
[Urological infections and antibiotic management in geriatric patients]. 38
31263939 2019
24
Randomized Clinical Trial Using Sterile Single Use and Reused Polyvinylchloride Catheters for Intermittent Catheterization with a Clean Technique in Spina Bifida Cases: Short-Term Urinary Tract Infection Outcomes. 38
30916625 2019
25
Ureteric implantation into the bowel portion of augmented bladders during kidney transplantation: a review of urological complications and outcomes. 38
30685889 2019
26
Incidence of multidrug resistance, pathogenicity island markers, and pathoadaptive FimH mutations in uropathogenic Escherichia coli isolated from asymptomatic hospitalized patients. 38
30835050 2019
27
Evidence-Informed Practice: Diagnostic Questions in Urinary Tract Infections in the Elderly. 38
31316695 2019
28
[Clinical presentation and performance of urine dipstick for diagnosis of urinary infection in geriatric population]. 38
31301943 2019
29
Orally Administered Combination of Hyaluronic Acid, Chondroitin Sulfate, Curcumin, and Quercetin in the Prevention of Postcoital Recurrent Urinary Tract Infections: Analysis of 98 Women in Reproductive Age After 6 Months of Treatment. 38
29389678 2019
30
Three versus five days of pivmecillinam for community-acquired uncomplicated lower urinary tract infection: A randomised, double-blind, placebo-controlled superiority trial. 38
31388664 2019
31
Urinary exosome as a potential biomarker for urinary tract infection. 38
30817089 2019
32
Bacterial urinary tract infection among adult renal transplant recipients at St. Paul's hospital millennium medical college, Addis Ababa, Ethiopia. 38
31366333 2019
33
[Experience of application of hormonal and probiotic therapy in the complex treatment of women in peri- and postmenopausal with chronic recurrent bacterial cystitis in the background of vulvovaginal atrophy]. 38
31356015 2019
34
Growth Rate of Escherichia coli During Human Urinary Tract Infection: Implications for Antibiotic Effect. 38
31336946 2019
35
Determination of Escherichia coli phylogroups in elderly patients with urinary tract infection or asymptomatic bacteriuria. 38
30648603 2019
36
Symptomatic urinary tract infection or asymptomatic bacteriuria? Improving care for the elderly. 38
30922927 2019
37
Predicting the risk of sepsis and causative organisms following urinary stones removal using urinary versus stone and stent cultures. 38
30972587 2019
38
Current practice on the management of pre-operative urine dipstick results in women undergoing gynaecological surgery in Wales. 38
31303088 2019
39
Risk of infection in patients undergoing urologic surgery based on the presence of asymptomatic bacteriuria: A prospective study. 38
31375294 2019
40
Factors associated with multidrug-resistant bacteria in a cohort of patients with asymptomatic bacteriuria who underwent urological surgery. 38
31331712 2019
41
Pandemic uropathogenic fluoroquinolone-resistant Escherichia coli have enhanced ability to persist in the gut and cause bacteriuria in healthy women. 38
31271206 2019
42
Clinical usefulness of iQ200/iChem Velocity workstation for screening of urine culture. 38
31208347 2019
43
Association between ultrasonographic appearance of urine and urinalysis in dogs and cats. 38
30868599 2019
44
Fosfomycin-trometamol for Urinary Tract Infections in Kidney Transplant Recipients. 38
30130327 2019
45
Community-acquired Staphylococcus aureus bacteriuria: a warning microbiological marker for infective endocarditis? 38
31174479 2019
46
[Evidence-based recommendations for the revision of the Austrian periodic health examination]. 38
31187373 2019
47
[Recommendations on the diagnosis and treatment of urinary tract infection]. 38
30979681 2019
48
Fimbriae reprogram host gene expression - Divergent effects of P and type 1 fimbriae. 38
31181116 2019
49
Asymptomatic bacteriuria in pediatric kidney transplant recipients: to treat or not to treat? A retrospective study. 38
30820703 2019
50
The evolution of catheter-associated urinary tract infection (CAUTI): Is it time for more inclusive metrics? 38
30915925 2019
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Variations for Bacteriuria

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Expression for Bacteriuria

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Search GEO for disease gene expression data for Bacteriuria.
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Pathways for Bacteriuria

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Pathways related to Bacteriuria according to GeneCards Suite gene sharing:

(show all 47)
# Super pathways Score Top Affiliating Genes
1
Innate Immune System 66
Show member pathways
 13.83 TLR5 TLR4 TLR2 TLR1 TIRAP IL6
2
Akt Signaling 64
Show member pathways
 13.1 TLR5 TLR4 TLR2 TLR1 TIRAP IL6
3
Human cytomegalovirus infection 37
Show member pathways
 12.91 TLR4 TLR2 TIRAP IL6 CXCL8 CCL2
4
Toll-like Receptor Signaling Pathway 37 1
Show member pathways
 12.9 TLR5 TLR4 TLR2 TLR1 TIRAP IL6
5
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways 66
Show member pathways
 12.66 TLR4 TIRAP IL6 CXCL8
6
NF-KappaB Family Pathway 64
Show member pathways
 12.63 TLR5 TLR4 TLR2 TLR1 IL6 CD40LG
7
TRAF Pathway 64
Show member pathways
 12.56 TLR5 TLR4 TLR2 TLR1 TIRAP CD40LG
8
Th17 cell differentiation 37
Show member pathways
 12.52 TLR5 TLR4 TLR2 IL6
9
NF-kappaB Signaling 4
12.49 TLR2 TLR1 CD40LG CCL2
10
Antigen processing-Cross presentation 66
Show member pathways
 12.42 TLR4 TLR2 TLR1 TIRAP
11
VEGF Pathway (Qiagen) 64
Show member pathways
 12.38 TLR5 TLR4 TLR2 TLR1 TIRAP
12
IL-17 Family Signaling Pathways 65
Show member pathways
 12.29 TLR5 TLR2 IL6 CXCL8 CCL2
13
Toll Comparative Pathway 64
Show member pathways
 12.27 TLR4 TIRAP IL6 CXCL8
14
Chemokine Superfamily Pathway: Human/Mouse Ligand-Receptor Interactions 65
Show member pathways
 12.2 CXCR1 CXCL8 CCL2
15
Tuberculosis 37
12.17 TLR4 TLR2 TLR1 TIRAP IL6
16
Toxoplasmosis 37
Show member pathways
 12.15 TLR4 TLR2 CD40LG
17
IL-1 Family Signaling Pathways 65
Show member pathways
 12.15 TLR5 TLR2 TIRAP IL6 CXCL8
18
Colorectal Cancer Metastasis 64
12.09 TLR5 TLR4 TLR2 TLR1 IL6
19
G-protein signaling Regulation of p38 and JNK signaling mediated by G-proteins 22
Show member pathways
 12.08 TLR5 TLR4 TLR2 TLR1 CXCR1 CXCL8
20
Microglia Activation During Neuroinflammation: Overview 65
Show member pathways
 12.03 TLR4 TLR2 TLR1 IL6
21
MAPK Pathway 71
Show member pathways
 12.02 TLR5 TLR4 TLR2 TLR1
22
Spinal Cord Injury 1
12 TLR4 IL6 CXCL8 CCL2
23
Diseases associated with the TLR signaling cascade 66
Show member pathways
 11.98 TLR5 TLR4 TLR2 TLR1 TIRAP IL6
24
Th1 Differentiation Pathway 65
Show member pathways
 11.97 TLR5 TLR4 TLR2 TLR1 IL6
25
Interleukin-4 and 13 signaling 66
11.92 IL6 CXCL8 CCL2
26
Amoebiasis 37
11.91 TLR4 TLR2 IL6 CXCL8
27
NF-kappa B signaling pathway 37
11.9 TLR4 TIRAP CXCL8 CD40LG
28
AGE-RAGE signaling pathway in diabetic complications 37
11.86 IL6 CXCL8 CCL2
29
Cytokine production by Th17 cells in CF (Mouse model) 22
Show member pathways
 11.82 TLR4 IL6 CXCL8
30
Phagocytosis of Microbes 64
11.81 TLR5 TLR4 TLR2 TLR1
31
Salmonella infection (KEGG) 37
11.8 TLR5 TLR4 IL6 CXCL8
32
Rheumatoid arthritis 37
11.77 TLR4 TLR2 IL6 CXCL8 CCL2
33
Pertussis 37
11.75 TLR4 TIRAP IL6 CXCL8
34
Bacterial infections in CF airways 22
Show member pathways
 11.72 TLR5 TLR4 TLR2 TLR1 TIRAP IL6
35
Photodynamic therapy-induced NF-kB survival signaling 1
Show member pathways
 11.64 IL6 CXCL8 CD40LG
36
Lung fibrosis 1
11.64 IL6 CXCL8 CCL2
37
Hepatitis C and Hepatocellular Carcinoma 1
11.54 IL6 CXCR1 CXCL8
38
Interleukin-10 signaling 66
11.52 IL6 CXCL8 CCL2
39
MSP-RON Signaling 64
11.51 TLR4 TLR2 CCL2
40
Legionellosis 37
11.47 TLR5 TLR4 TLR2 IL6 CXCL8
41
Validated transcriptional targets of AP1 family members Fra1 and Fra2 1
11.35 IL6 CXCL8 CCL2
42
A-beta Pathways: Uptake and Degradation 65
11.31 TLR4 CD40LG CCL2
43
IL1 and megakaryocytes in obesity 1
11.19 TLR2 TLR1 CCL2
44
G-protein signaling_RhoB regulation pathway 22
11.18 IL6 CXCL8 CD40LG CCL2
45
Overview of nanoparticle effects 1
10.97 IL6 CXCL8
46
G-protein signaling_Rap2B regulation pathway 22
10.9 IL6 CXCL8 CD40LG CCL2
47
Malaria 37
10.79 TLR4 TLR2 IL6 CXCL8 CD40LG CCL2
Sources

GO Terms for Bacteriuria

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Cellular components related to Bacteriuria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.61 TLR5 TLR4 TLR2 TLR1 TIRAP PRF1
2 Toll-like receptor 1-Toll-like receptor 2 protein complex GO:0035354 8.62 TLR2 TLR1

Biological processes related to Bacteriuria according to GeneCards Suite gene sharing:

(show all 43)
# Name GO ID Score Top Affiliating Genes
1 response to lipopolysaccharide GO:0032496 9.86 TLR4 TLR2 TIRAP
2 chemotaxis GO:0006935 9.85 CXCR1 CXCL8 CCL2
3 cellular response to interferon-gamma GO:0071346 9.83 TLR4 TLR2 CCL2
4 cellular response to lipopolysaccharide GO:0071222 9.83 TLR5 TLR4 IL6 CXCL8 CCL2
5 defense response to Gram-positive bacterium GO:0050830 9.82 TLR2 TIRAP IL6
6 neutrophil chemotaxis GO:0030593 9.81 CXCR1 CXCL8 CCL2
7 chemokine-mediated signaling pathway GO:0070098 9.81 CXCR1 CXCL8 CCL2
8 positive regulation of interleukin-6 production GO:0032755 9.79 TLR4 TLR2 IL6
9 positive regulation of tumor necrosis factor production GO:0032760 9.78 TLR4 TLR2 TIRAP
10 immune response GO:0006955 9.76 TLR4 TLR2 TLR1 IL6 CXCR1 CXCL8
11 toll-like receptor signaling pathway GO:0002224 9.74 TLR4 TLR2 TLR1
12 lipopolysaccharide-mediated signaling pathway GO:0031663 9.73 TLR4 TLR2 CCL2
13 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.73 TLR4 TLR2 TIRAP IL6 CD40LG CAT
14 positive regulation of interleukin-8 production GO:0032757 9.71 TLR5 TLR4 TLR2 TIRAP
15 positive regulation of interferon-beta production GO:0032728 9.69 TLR4 TLR2
16 positive regulation of interleukin-10 production GO:0032733 9.69 TLR4 TLR2 CD40LG
17 positive regulation of neutrophil chemotaxis GO:0090023 9.68 TIRAP CXCL8
18 positive regulation of endothelial cell apoptotic process GO:2000353 9.68 CD40LG CCL2
19 response to fatty acid GO:0070542 9.68 TLR2 CAT
20 positive regulation of interleukin-8 secretion GO:2000484 9.67 TLR2 TLR1
21 response to molecule of bacterial origin GO:0002237 9.67 TLR2 CXCL8
22 PERK-mediated unfolded protein response GO:0036499 9.67 CXCL8 CCL2
23 positive regulation of chemokine production GO:0032722 9.67 TLR4 TLR2 IL6
24 positive regulation of interleukin-12 production GO:0032735 9.67 TLR4 TLR2 TIRAP CD40LG
25 I-kappaB phosphorylation GO:0007252 9.66 TLR4 TLR2
26 cell activation GO:0001775 9.66 TLR2 TLR1
27 positive regulation of tumor necrosis factor biosynthetic process GO:0042535 9.65 TLR4 TLR1
28 macrophage activation GO:0042116 9.65 TLR4 TLR1
29 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.65 TLR4 TLR2 CCL2
30 positive regulation of toll-like receptor 2 signaling pathway GO:0034137 9.63 TLR1 TIRAP
31 cellular response to lipoteichoic acid GO:0071223 9.63 TLR4 TLR2 TIRAP
32 positive regulation of interleukin-6 biosynthetic process GO:0045410 9.62 TLR1 TIRAP
33 positive regulation of toll-like receptor signaling pathway GO:0034123 9.6 TLR5 TLR2
34 toll-like receptor TLR1:TLR2 signaling pathway GO:0038123 9.59 TLR2 TLR1
35 cellular response to triacyl bacterial lipopeptide GO:0071727 9.58 TLR2 TLR1
36 cellular response to bacterial lipopeptide GO:0071221 9.58 TLR2 TIRAP
37 positive regulation of cellular response to macrophage colony-stimulating factor stimulus GO:1903974 9.55 TLR4 TLR2
38 detection of triacyl bacterial lipopeptide GO:0042495 9.54 TLR2 TLR1
39 regulation of cytokine secretion GO:0050707 9.5 TLR5 TLR2 TLR1
40 MyD88-dependent toll-like receptor signaling pathway GO:0002755 9.35 TLR5 TLR4 TLR2 TLR1 TIRAP
41 inflammatory response GO:0006954 9.28 TLR5 TLR4 TLR2 TLR1 TIRAP IL6
42 signal transduction GO:0007165 10.13 TLR5 TLR4 TLR2 TLR1 TIRAP CXCR1
43 innate immune response GO:0045087 10.01 TLR5 TLR4 TLR2 TLR1 TIRAP

Molecular functions related to Bacteriuria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.73 TLR4 TLR2 TLR1 TIRAP PRF1 CAT
2 protein heterodimerization activity GO:0046982 9.67 TLR4 TLR2 TLR1 TIRAP
3 lipopeptide binding GO:0071723 9.32 TLR2 TLR1
4 cytokine activity GO:0005125 9.26 IL6 CXCL8 CD40LG CCL2
5 lipopolysaccharide receptor activity GO:0001875 9.16 TLR4 TLR2
6 Toll-like receptor 2 binding GO:0035663 8.62 TLR1 TIRAP
Sources

Sources for Bacteriuria

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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