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MCID: BCT004
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Bacteriuria

Categories: Nephrological diseases
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Aliases & Classifications for Bacteriuria

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MalaCards integrated aliases for Bacteriuria:

Name: Bacteriuria 11 53 43 14 71 75

Classifications:

MalaCards categories:
Anatomical: Nephrological diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 11 DOID:1412
MeSH 43 D001437
SNOMED-CT 68 61373006
UMLS 71 C0004659
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Summaries for Bacteriuria

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Disease Ontology: 11 A urinary system disease which consists of the presence of bacteria in urine.

MalaCards based summary: Bacteriuria is related to urethral syndrome and pyuria. An important gene associated with Bacteriuria is TLR4 (Toll Like Receptor 4), and among its related pathways/superpathways are MIF Mediated Glucocorticoid Regulation and Innate Immune System. The drugs Trimethoprim and Sulfamethoxazole have been mentioned in the context of this disorder. Affiliated tissues include kidney, spinal cord and prostate, and related phenotypes are homeostasis/metabolism and neoplasm

Wikipedia: 75 Bacteriuria is the presence of bacteria in urine. Bacteriuria accompanied by symptoms is a urinary tract... more...
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Related Diseases for Bacteriuria

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Diseases related to Bacteriuria via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 684)
# Related Disease Score Top Affiliating Genes
1 urethral syndrome 31.4 IL6 CXCL8 CXCL1 CRP
2 pyuria 31.1 IL6 CRP ALB
3 vaginitis 30.3 TLR4 TLR2 IL6 CXCL8
4 chronic pyelonephritis 30.3 UMOD CRP ALB
5 klebsiella pneumonia 30.2 CRP ALB
6 urinary tract infection 30.1 UMOD TLR4 TLR2 PAPOLG IL6 CXCL8
7 cystitis 30.1 UMOD TLR4 IL6 CXCL8 CXCL1 CRP
8 cervicitis 30.1 TLR4 TLR2 IL6 CXCL8
9 conjunctivitis 30.0 TLR4 IL6 CXCL8 CCL2
10 endometritis 30.0 TLR4 TLR2 IL6 CXCL8 CXCL1
11 pyelonephritis 30.0 UMOD TLR4 IL6 CXCR2 CXCR1 CXCL8
12 human immunodeficiency virus type 1 29.9 CXCR2 CXCR1 CXCL1 CCL2
13 urolithiasis 29.8 UMOD IL6 CCL2 ALB
14 toxic shock syndrome 29.8 TLR4 TLR2 IL6 CXCL8 CRP
15 schistosomiasis 29.8 CRP CD40LG CCL2 ALB
16 vesicoureteral reflux 29.8 UMOD CXCL8 CRP ALB
17 nutritional deficiency disease 29.8 IL6 CRP ALB
18 ureterolithiasis 29.8 CRP ALB
19 acute cystitis 29.7 UMOD TLR4 PAPOLG IL6 CXCL8 CXCL1
20 endocarditis 29.7 TLR2 IL6 CXCL8 CRP ALB
21 gastroenteritis 29.7 IL6 CXCL8 CRP ALB
22 pre-eclampsia 29.7 TLR4 IL6 IL18 CXCL8 CRP ALB
23 membranous nephropathy 29.7 CD79A CCL2 ALB
24 type 1 diabetes mellitus 29.7 IL6 IL18 CXCL8 CD79A ALB
25 infective endocarditis 29.6 IL6 CXCL8 CRP ALB
26 hydronephrosis 29.6 IL6 CXCL8 CRP CCL2 ALB
27 preterm premature rupture of the membranes 29.6 TLR4 TLR2 IL6 CXCL8 CRP
28 pericarditis 29.6 IL6 CXCL8 CRP
29 urinary tract obstruction 29.6 UMOD IL6 CRP CCL2 ALB
30 typhoid fever 29.6 TLR5 TLR4 IL6 CRP ALB
31 diarrhea 29.5 TLR4 IL6 CXCL8 CXCL1 CD40LG ALB
32 vaginal discharge 29.5 IL6 CXCL8 CRP ALB
33 decubitus ulcer 29.5 IL6 CXCL8 CRP ALB
34 iron deficiency anemia 29.5 IL6 CRP CAT
35 acute pyelonephritis 29.5 TLR4 PAPOLG IL6 CXCR2 CXCR1 CXCL8
36 primary biliary cholangitis 29.5 TLR4 IL6 CXCL8 CD79A CD40LG CCL2
37 mediastinitis 29.5 IL6 CRP ALB
38 salmonellosis 29.5 TLR5 TLR4 TLR2 IL6 IL18 CXCL8
39 asphyxia neonatorum 29.5 IL6 CRP ALB
40 hemorrhoid 29.4 IL6 CRP ALB
41 urethritis 29.4 TLR4 TLR2 IL6 CXCL8 CRP ALB
42 cholecystitis 29.4 TLR4 CRP ALB
43 chronic kidney disease 29.4 UMOD IL6 CRP CD79A ALB
44 bilirubin metabolic disorder 29.4 IL6 CXCL8 CRP ALB
45 chorioamnionitis 29.4 TLR4 IL6 IL18 CXCL8 CRP CCL2
46 pain agnosia 29.4 IL6 CRP ALB
47 osteomyelitis 29.4 TLR4 TLR2 IL6 CXCL8 CRP CCL2
48 pharyngitis 29.4 TLR2 TLR1 IL6 CXCL8 CRP
49 urticaria 29.4 IL6 IL18 CXCL8 CRP
50 neutropenia 29.4 TLR4 IL6 CXCR2 CXCL8 CRP CD40LG

Graphical network of the top 20 diseases related to Bacteriuria:



Diseases related to Bacteriuria
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Symptoms & Phenotypes for Bacteriuria

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GenomeRNAi Phenotypes related to Bacteriuria according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 no effect GR00402-S-1 10.19 ALB CAT CCL2 CD40LG CD79A CRP
2 no effect GR00402-S-2 10.19 ALB CAT CCL2 CD40LG CD79A CRP

MGI Mouse Phenotypes related to Bacteriuria:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.32 ALB CAT CCL2 CD40LG CD79A CRP
2 neoplasm MP:0002006 10.13 ALB CAT CCL2 CD79A CXCR2 IL6
3 cellular MP:0005384 10.13 ALB CAT CCL2 CD40LG CD79A CXCR2
4 liver/biliary system MP:0005370 10.09 ALB CCL2 CD79A CXCR2 IL6 PRF1
5 cardiovascular system MP:0005385 10.07 ALB CCL2 CD40LG CRP CXCL1 CXCR2
6 renal/urinary system MP:0005367 10.06 ALB CD40LG CD79A CXCR2 IL6 TLR2
7 immune system MP:0005387 10.06 ALB CCL2 CD40LG CD79A CRP CXCL1
8 adipose tissue MP:0005375 9.95 CCL2 IL18 IL6 TLR2 TLR4 TLR5
9 hematopoietic system MP:0005397 9.8 CCL2 CD40LG CD79A CXCL1 CXCR1 CXCR2
10 mortality/aging MP:0010768 9.47 ALB CAT CCL2 CD40LG CD79A CXCR2
Sources

Drugs & Therapeutics for Bacteriuria

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Drugs for Bacteriuria (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 76)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Trimethoprim Approved, Vet_approved Phase 4 738-70-5 5578
2
Sulfamethoxazole Approved Phase 4 723-46-6 5329
3
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
4
Fosfomycin Approved Phase 4 23155-02-4 446987
5
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1, 93107-08-5 2764
6
Levoleucovorin Approved, Experimental, Investigational Phase 4 68538-85-2, 58-05-9, 73951-54-9 149436 6006
7
Iodine Approved, Investigational Phase 4 7553-56-2 807
8
Povidone-iodine Approved Phase 4 25655-41-8
9
Povidone K30 Approved, Experimental, Withdrawn Phase 4 9003-39-8 6917 131751496
10
Folic acid Approved, Nutraceutical, Vet_approved Phase 4 59-30-3 6037
11
Cadexomer iodine Experimental Phase 4 94820-09-4
12 Dermatologic Agents Phase 4
13 Anti-Bacterial Agents Phase 4
14 Anti-Infective Agents Phase 4
15 Trimethoprim, Sulfamethoxazole Drug Combination Phase 4
16 Pharmaceutical Solutions Phase 4
17 Folic Acid Antagonists Phase 4
18 Folate Phase 4
19 Vitamin B9 Phase 4
20 Antiprotozoal Agents Phase 4
21 Antiparasitic Agents Phase 4
22 Vitamin B Complex Phase 4
23 Antimalarials Phase 4
24 Cytochrome P-450 Enzyme Inhibitors Phase 4
25 Blood Substitutes Phase 4
26 Plasma Substitutes Phase 4
27
Levofloxacin Approved, Investigational Phase 3 100986-85-4 149096
28
Ofloxacin Approved Phase 3 82419-36-1 4583
29 Cranberry Approved, Investigational Phase 3
30
Lomefloxacin Approved, Investigational Phase 3 98079-51-7 3948
31 Anthocyanidin Phase 3
32
Proanthocyanidin Phase 3 21881649
33
Procyanidin Phase 3 4852-22-6 147299
34 Antitubercular Agents Phase 2
35 Antibiotics, Antitubercular Phase 2
36
Methenamine Approved, Vet_approved Phase 1 100-97-0 4101
37
Nitric Oxide Approved Phase 1 10102-43-9 145068
38 Methenamine mandelate Phase 1
39 Methenamine hippurate Phase 1
40 Neurotransmitter Agents Phase 1
41 Bronchodilator Agents Phase 1
42 Anti-Asthmatic Agents Phase 1
43 Endothelium-Dependent Relaxing Factors Phase 1
44 Vasodilator Agents Phase 1
45 Respiratory System Agents Phase 1
46 Antioxidants Phase 1
47 Protective Agents Phase 1
48
Ampicillin Approved, Vet_approved 69-53-4 6249
49
Cefazolin Approved 25953-19-9 33255
50
Sulbactam Approved 68373-14-8 5316

Interventional clinical trials:

(show top 50) (show all 64)
# Name Status NCT ID Phase Drugs
1 The Impact of Antimicrobial Treatment for Asymptomatic Bacteriuria in Renal Transplant Patients Unknown status NCT02113774 Phase 4
2 Comparison of the Effect of Applying Povidone-iodine and Chlorhexidine Solutions for Perinea Washing on Bacteriuria Rate and Type in Patients With Urinary Catheter in Intensive Care Unit Unknown status NCT02032394 Phase 4 Povidone-iodine;Chlorhexidine;Normal saline
3 Clinical Impact of Bacteriuria on Chronic Inflammation in Asymptomatic Hemodialysis Patients Unknown status NCT01570556 Phase 4
4 The Bacteriuria in Renal Transplantation (BiRT) Study: A Prospective, Randomized, Parallel-group, Multicenter, Open-label, Superiority Trial Comparing Antibiotics Versus no Treatment in the Prevention of Symptomatic Urinary Tract Infection in Kidney Transplant Recipients With Asymptomatic Bacteriuria Completed NCT01871753 Phase 4
5 Management of Sub-Clinical Bacteriuria in Pregnancy: A Feasibility Trial Completed NCT03275623 Phase 4 Antibiotic
6 Perioperative Disodium Fosfomycin in the Prophylaxis of Urinary Tract Infection in Kidney Transplant Recipients. Controlled Clinical Trial (PERIFOS Trial) Completed NCT03235947 Phase 4 Fosfomycin disodium;Trimethoprim / Sulfamethoxazole;Intravenous placebo
7 Use of Antibiotic Prophylaxis on Urethral Catheter Withdrawal: A Randomized Double-Blind Placebo-Controlled Trial Completed NCT00126698 Phase 4 trimethoprim-sulfamethoxazole;ciprofloxacin
8 Fosfomycin-Trometamol in Urinary Tract Infection Prophylaxis After Kidney Transplantation. Randomized Controlled Trial. Completed NCT01820897 Phase 4 Fosfomycin-Trometamol;Sulfamethoxazole trimethoprim
9 A Randomized Trial of Betadine Bladder Irrigations vs. Standard of Care Prior to Indwelling Catheter Removal to Reduce Bacteriuria and Catheter-Associated Urinary Tract Infections Terminated NCT03447639 Phase 4 Povidone-iodine irrigation
10 A Randomized, Controlled Trial of Cranberry Capsules for UTI Prevention in Nursing Home Residents Completed NCT01691430 Phase 3
11 A Multicenter, Randomized Study To Compare The Safety And Efficacy Of Oral Levofloxacin With That Of Lomefloxacin HCl In The Treatment Of Complicated Urinary Tract Infections In Adults Completed NCT00258102 Phase 3 Levofloxacin
12 A Multicenter, Double-Blind, Randomized Study To Compare The Safety And Efficacy Of Oral Levofloxacin With That Of Ciprofloxacin HCl In The Treatment Of Complicated Urinary Tract Infections In Adults Completed NCT00258089 Phase 3 Levofloxacin
13 Effect of Standardization of Urine Collection Using PEEZY Device as Compared to Clean Catch in the Detection of Asymptomatic Bacteriuria in an Obstetric Population Recruiting NCT05554081 Phase 3
14 Empirical Use of Fosfomycin as a Single Dose Oral Treatment of Asymptomatic Bacteriuria Unknown status NCT03548129 Phase 2 phosphomycin;Culture specific antibiotic therapy
15 A Pilot Randomized Control Study of Shortening Antibiotic Treatment Duration For Asymptomatic Bacteriuria Within A Month After Kidney Transplantation Completed NCT02575495 Phase 2 7 days course of antibiotic treatment;14 days course of antibiotic treatment
16 A Phase IIa Open Label Study to Evaluate the Safety and Antimicrobial Effects of NVC-422 on Bacteriuria in Chronically Catheterized Subjects Completed NCT00781339 Phase 2 sodium 2-(dichloroamino)-2-methylpropane-1-sulfonate monohydrate
17 Prevention of Nosocomial Escherichia Coli Infections After Placement of an Indwelling Catheter During Pelvic Surgery: a Randomized, Prospective, Double Blind Study for the Evaluation of Cranberry (Vaccinium Macrocarpon) Gel Capsules Completed NCT01114347 Phase 2
18 Pemberian Antibiotik Profilaksis Pada Biopsi Prostat Transperineal di RSUPN Dr. Cipto Mangunkusumo: Uji Klinis Acak Terkontrol Recruiting NCT04985110 Phase 2 Cotrimoxazole;Placebo
19 Bacteriuria Eradication Through Probiotics Unknown status NCT00717600 Phase 1
20 Cranberry for Prevention of Bacteriuria in Pregnancy Completed NCT00093938 Phase 1 Cranberry juice
21 Pilot Study: Dosing Study of Cranberry Capsules for the Prevention of Bacteriuria in Nursing Home Residents Completed NCT01033383 Phase 1
22 Prospective, Phase I, Single-Center, Evaluation of the Safety and Tolerability of Nitric Oxide Impregnated Urinary Catheters in Patients Undergoing Radical Prostatectomy Completed NCT02277171 Phase 1
23 Retained Urine Volume and Bacteriuria in Traditional Versus Vented Urine Drainage Systems Withdrawn NCT02052674 Phase 1
24 'A Pilot Study To Assess The Impact Of A Camstent Coated Catheter On Clinical Bacteriuria.' Unknown status NCT04658719
25 "Comparison of the Effectiveness of 24-hour and 72-hour Peri-procedural Antimicrobial Prophylaxis in Patients Undergoing Endourological Procedures and ESWL Presenting With Asymptomatic Bacteriuria of Enterobacteriacae ESBL+ Origin" Unknown status NCT04152369
26 Postnatal Prevalence of Bacteriuria in Women With Catheter Versus no Catheter in Labour: a Prospective Cohort Study Unknown status NCT03914144
27 Intraoperative One-Time Catheterization in Short Gynecologic Procedures and Its Potential Effect on Symptomatic and Asymptomatic Bacteriuria Unknown status NCT01926756
28 Health Care-associated Bacteriuria in Geriatric Wards in Strasbourg's University Hospital : a Comparative Study of Bacterial Ecology Between 2003, 2007 and 2017 Unknown status NCT03577769
29 Efficacy of Bladder Catheters Lubricated With a Biofilm Disruptive Gel, in Reducing Catheter-associated Bacteriuria (CAB) Compared to Standard of Care: A PILOT Clinical Trial Unknown status NCT03176394
30 Effectiveness of Three Different Times of Starting Antibiotic Prophylaxis in Patients With Asymptomatic Bacteriuria Scheduled for Urological Surgery. A Randomized Multicentric Clinical Trial Unknown status NCT03269604
31 Asymptomatic Bacteriuria & Risk of Urinary Tract Infection in Renal Transplants Unknown status NCT01349738 Antibiotic
32 a Symptomatic Bacteriuria in Pregnant Females Unknown status NCT03499561
33 Antibiotic Treatment Versus no Therapy in Kidney Transplant Recipients With Asymptomatic Bacteriuria. A Prospective Randomized Study. Unknown status NCT01771432 Antibiotic treatment
34 Comparison of Verbal Versus Video Instruction in the Collection of Clean Catch Urine in Pregnant Women Undergoing Testing for Asymptomatic Bacturia: Randomized Control Trial Unknown status NCT03658356
35 Incidence of Symptomatic and Asymptomatic Bacteriuria After Urodynamic Study With or Without Antibiotic Prophylaxis in Women With Urinary Incontinence Completed NCT03106103
36 Screening and Treatment of Asymptomatic Bacteriuria in the First Two Months After Kidney Transplant. Randomized Control Trial Completed NCT04333602
37 Effectiveness of Cranberry Ingestion on Bacterial Adhesion: Adjunct to Pilot Study of Daily Cranberry Ingestion of Cranberry Juice for the Prevention of Asymptomatic Bacteriuria in Pregnancy Completed NCT00506025
38 Induced Asymptomatic E. Coli 83972 Bacteriuria in Patients With Recurrent Urinary Tract Infections and Bladder Dysfunction- is There a Protective Effect Against Recurrent Symptomatic Infections? A Blinded Placebo Controlled Cross-over Study. Completed NCT00927316
39 Reduction of Bacteriuria in Subjects Practicing Intermittent Catheterization Completed NCT01143116
40 Guideline Implementation to Decrease Inappropriate Bacteriuria Treatment Completed NCT01052545
41 Randomized Clinical Trial on the Safety and Efficacy of Lactobacillus Reuteri DSM 16666/ATCC 55845 & Lactobacillus Reuteri DSM 17938 for Treatment of Pregnant Women With Asymptomatic Bacteriuria or Uncomplicated Acute Cystitis Completed NCT03362697 Antibiotics
42 Effect of Systematic Search and Antimicrobial Treatment of Asymptomatic Bacteriuria in Kidney Transplant Recipients in the Incidence of Acute Pyelonephritis: a Pragmatic Prospective Randomized Controlled Study. Completed NCT02373085
43 Safety and Effectiveness of a Laboratory Intervention to Effectively NOT Treat Asymptomatic Bacteriuria (SALIENT-A) Completed NCT03445312
44 Open Prospective Study on Reduction of Bacteriuria Following Bladder Irrigation With Chlorhexidine Completed NCT01782404
45 Behavioral Economics Applications to Geriatrics Leveraging EHRs Completed NCT03704389
46 Restricted Reporting for Positive Urine Cultures Randomized Controlled Trial Completed NCT02797613
47 Behavioral Economics Applications to Geriatrics Leveraging EHRs R33 Trial Completed NCT04289753
48 The Frequency of Leukocytes and Nitrites in the Urine of Healthy Adults Completed NCT04055675
49 Avoiding Bacterial Contamination of Clean Catch Urine Cultures in Ambulatory Patients in the Emergency Department Completed NCT03131609
50 Modified Reporting of Positive Urine Cultures Collected From Long Term Care, a Randomized Controlled Trial Completed NCT03554603

Search NIH Clinical Center for Bacteriuria

Inferred drug relations via UMLS 71 / NDF-RT 50 :


Methenamine
methenamine hippurate
methenamine mandelate
METHENAMINE SULFOSALICYLATE

Cochrane evidence based reviews: bacteriuria

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Genetic Tests for Bacteriuria

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Anatomical Context for Bacteriuria

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Organs/tissues related to Bacteriuria:

MalaCards : Kidney, Spinal Cord, Prostate, Cervix, Colon, Skin, Liver
Sources

Publications for Bacteriuria

About this section

Articles related to Bacteriuria:

(show top 50) (show all 6344)
# Title Authors PMID Year
1
Comparison of urinary proteins in calcium stone formers and healthy individuals: a case-control study. 53 62
16493220 2006
2
Urinary Tamm-Horsfall protein and citrate: a case-control study of inhibitors and promoters of calcium stone formation. 53 62
17629875 2005
3
Development and pilot testing of EHR-nudges to reduce overuse in older primary care patients. 62
36115068 2023
4
Prophylactic Antimicrobial Prescribing in Australian Residential Aged-Care Facilities: Improvement is Required. 62
35962922 2022
5
Effect of intermittent bladder flushing on recurrence rate in feline urethral obstruction: 72 cases. 62
36467381 2022
6
Catheter-associated urinary tract infection by Pseudomonas aeruginosa progresses through acute and chronic phases of infection. 62
36469780 2022
7
Evaluation of screening with urine dipsticks and renal ultrasonography for 3-year-olds in Chiba City over 30 years. 62
36056980 2022
8
Urinary tract infections in patients with multiple sclerosis and different methods of bladder evacuation. 62
36216764 2022
9
Prevalence of bacteriuria in cats with neurogenic bladder. 62
35835971 2022
10
Vitamin K antagonist-associated microscopic hematuria. 62
35850278 2022
11
Urodynamic risk factors of asymptomatic bacteriuria in men with non-neurogenic lower urinary tract symptoms. 62
36264427 2022
12
A Systematic Review of Antimicrobial Stewardship Interventions to Improve Management of Bacteriuria in Hospitalized Adults. 62
36367099 2022
13
Antibiotic Stewardship Program Reduces Use of Urine Cultures and Antibiotics for Asymptomatic Bacteriuria. 62
36261910 2022
14
Bacteriuria revisited. 62
35791981 2022
15
A preventable, life-altering case of fluoroquinolone-associated tendonitis. 62
36282576 2022
16
Rectal culture-based versus empirical antibiotic prophylaxis to prevent infectious complications in men undergoing transrectal prostate biopsy: a randomized, non-blinded multicenter trial. 62
36419331 2022
17
[Urinary tract infections in patients with neurogenic lower urinary tract dysfunction]. 62
36448946 2022
18
[Blebbing of plasma membrane of lymphocytes in infectious complications of urolithiasis]. 62
36382815 2022
19
Assessment of early kidney injury caused by asymptomatic bacteriuria in children with type 1 diabetes. 62
36344956 2022
20
The Diagnostic Accuracy Of Procalcitonin for Urinary Tract Infection in Hospitalized Older Adults: a Prospective Study. 62
34997392 2022
21
Urinary tract infection caused by bacterial pathogens of the respiratory tract in children. 62
36382945 2022
22
Bacterial Urinary Tract Infection and Early Asymptomatic Bacteriuria in Kidney Transplantation Still Negatively Affect Kidney Transplant Outcomes in the Era of Modern Immunosuppression and Cotrimoxazole Prophylaxis. 62
36428552 2022
23
Urine testing is associated with inappropriate antibiotic use and increased length of stay in emergency department patients. 62
36281377 2022
24
Catheter-Associated Urinary Tract Infection (CAUTI). 62
36407206 2022
25
Diagnostic stewardship for urinary tract infection: A snapshot of the expert guidance. 62
36192024 2022
26
A global perspective on management of bacterial infections in pregnancy: a systematic review of international guidelines. 62
33115310 2022
27
Prevalence and predictors of urine culture contamination in primary care: A cross-sectional study. 62
35914376 2022
28
Etiology and Antibiotic Susceptibility Patterns of Urinary Tract Infections in Children in A General Hospital in Kuwait: A 5-Year Retrospective Study. 62
36310010 2022
29
Modified reporting of positive urine cultures to reduce treatment of asymptomatic bacteriuria in long-term care facilities: a randomized controlled trial. 62
36262767 2022
30
Antibiotic use for asymptomatic bacteriuria in children with neurogenic bladder. 62
36314224 2022
31
Purple urine bag syndrome: A case report. 62
36261954 2022
32
POCT urine dipstick versus central laboratory analyses: Diagnostic performance and logistics in the medical emergency department. 62
36279905 2022
33
Urine bacterial culture growth and association with urine sedimentation and clinical findings in cats with acute kidney injury. 62
35748789 2022
34
Intravesical Instillation of OnabotulinumtoxinA in the Treatment of Refractory Overactive Bladder in Participants with Urinary Incontinence. 62
35830550 2022
35
Leukocyte Esterase and Nitrite Urine Reagent Strip Utility Under Altered Assay Conditions in Dogs. 62
36049239 2022
36
Sulopenem or Ciprofloxacin for the Treatment of Uncomplicated Urinary Tract Infections in Women: A Phase 3 Randomized Trial. 62
36069202 2022
37
No adverse consequences associated with targeting clinical signs to initiate antimicrobial treatment of postoperative subclinical bacteriuria in dogs following surgical decompression of Hansen type I thoracolumbar disk herniation. 62
36166501 2022
38
Bacterial profile and antimicrobial resistance patterns of common bacteria among pregnant women with bacteriuria in Ethiopia: a systematic review and meta-analysis. 62
35032208 2022
39
Imaging of Group B Streptococcus infection in pyonephrosis: a case report. 62
35846511 2022
40
Maternal age and body mass index as risk factors for rectovaginal colonization with group B streptococci. 62
36086996 2022
41
Definitions of Urinary Tract Infection Used in Interventional Studies Involving Neurourological Patients-A Systematic Review. 62
34404618 2022
42
Role of oral pentosan polysulfate in Bacillus Calmette-Guérin therapy in patients with non-muscle-invasive bladder cancer. 62
36067999 2022
43
Correlation of Pyuria and Bacteriuria in Acute Care. 62
35580716 2022
44
Sulopenem For The Treatment of Complicated Urinary Tract Infection Including Pyelonephritis: A Phase 3 Randomized Trial. 62
36068705 2022
45
Diagnostic work-up of urinary tract infections in pregnancy: study protocol of a prospective cohort study. 62
36104146 2022
46
Catheter-associated urinary tract infection: an overview. 62
36036578 2022
47
Septic Shock Induced by Acute Pyelonephritis Resulting from Kidney Stones Treated by Double-J Ureteral Stents in a Pregnant Woman: A Case Report and Literature Review. 62
35943910 2022
48
Can Urinalysis and Past Medical History of Kidney Stones Predict Urine Antibiotic Resistance? 62
36205684 2022
49
The dienogest-related cystitis in women with endometriosis: a prospective, controlled, comparative study. 62
35653789 2022
50
Systematic review of the effect of D-mannose with or without other drugs in the treatment of symptoms of urinary tract infections/cystitis (Review). 62
35815191 2022
Sources

Variations for Bacteriuria

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Expression for Bacteriuria

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Search GEO for disease gene expression data for Bacteriuria.
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Pathways for Bacteriuria

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Pathways related to Bacteriuria according to GeneCards Suite gene sharing:

(show top 50) (show all 56)
# Super pathways Score Top Affiliating Genes
1
MIF Mediated Glucocorticoid Regulation 64
Show member pathways
 13.65 TLR4 IL6 IL18 CXCR2 CXCR1 CXCL8
2
Innate Immune System 66
Show member pathways
 13.61 CAT CCL2 CD40LG CD79A CRP CXCL1
3
PAK Pathway 64
Show member pathways
 13.32 IL6 IL18 CXCR2 CXCR1 CXCL8 CXCL1
4
Toll-like receptor signaling pathway 74
Show member pathways
 12.86 TLR5 TLR4 TLR2 TLR1 TIRAP IL6
5
CCR5 Pathway in Macrophages 64
Show member pathways
 12.85 CXCR2 CXCR1 CXCL8 CXCL1 CCL2
6
NF-KappaB Family Pathway 64
Show member pathways
 12.73 TLR5 TLR4 TLR2 TLR1 IL6 CD40LG
7
TNF Superfamily - Human Ligand-Receptor Interactions and their Associated Functions 65
Show member pathways
 12.65 TLR5 TLR4 TLR2 TLR1 TIRAP CD40LG
8
IL-1 Family Signaling Pathways 65
Show member pathways
 12.64 CXCL8 IL18 IL6 TIRAP TLR2 TLR5
9
NF-kappaB Signaling 3
12.6 TLR2 TLR1 CD79A CD40LG CCL2
10
Akt Signaling 64
Show member pathways
 12.58 TLR5 TLR4 TLR2 TLR1 TIRAP IL6
11
VEGF Pathway (Qiagen) 64
Show member pathways
 12.47 TLR5 TLR4 TLR2 TLR1 TIRAP
12
Bacterial infections in CF airways 22
Show member pathways
 12.35 TLR5 TLR4 TLR2 TLR1 TIRAP IL6
13
Antigen processing-Cross presentation 66
Show member pathways
 12.34 TLR4 TLR2 TLR1 TIRAP
14
Toll Comparative Pathway 64
Show member pathways
 12.31 TLR4 TIRAP IL6 CXCL8
15
IL-17 Family Signaling Pathways 65
Show member pathways
 12.28 TLR5 TLR2 IL6 CXCL8 CXCL1 CCL2
16
Diseases of Immune System 66
Show member pathways
 12.27 TLR5 TLR4 TLR2 TLR1 TIRAP
17
Colorectal Cancer Metastasis 64
12.22 TLR5 TLR4 TLR2 TLR1 IL6
18
Integrin family cell surface interactions 61
Show member pathways
 12.11 TLR5 TLR4 TLR2 TLR1
19
Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions 65
Show member pathways
 12.07 CXCR2 CXCR1 CXCL8 CXCL1 CCL2
20
MAPK Pathway 70
Show member pathways
 12.05 TLR5 TLR4 TLR2 TLR1
21
Toll-Like receptor Signaling Pathways 65
Show member pathways
 12.05 TLR5 TLR4 TLR2 TLR1 TIRAP IL6
22
Spinal cord injury 74
12.01 TLR4 IL6 CXCL8 CXCL1 CCL2
23
Interleukin-4 and Interleukin-13 signaling 66
11.99 IL6 IL18 CXCL8 CCL2
24
Cytokine production by Th17 cells in CF (Mouse model) 22
Show member pathways
 11.92 CXCL1 CXCL8 IL6 TLR4
25
Th17 Differentiation 65
Show member pathways
 11.89 TLR5 TLR4 TLR2 TLR1 IL6
26
Allograft rejection 74
11.86 PRF1 CXCL8 CD40LG
27
Corticotropin-releasing hormone signaling pathway 74
11.85 TLR4 IL18 CXCL8
28
Network map of SARS-CoV-2 signaling pathway 74
Show member pathways
 11.82 IL6 CXCL8 CRP CCL2
29
Acute viral myocarditis 74
11.8 TLR5 TLR4 IL6 CD40LG
30
IL27-mediated signaling events 61
Show member pathways
 11.8 TLR5 TLR4 TLR2 TLR1 IL6 IL18
31
Extrafollicular B cell activation by SARS-CoV-2 74
11.73 TLR4 IL6 CRP CD79A CD40LG
32
AP-1 transcription factor network 61
11.72 IL6 CXCL8 CCL2
33
Photodynamic therapy-induced NF-kB survival signaling 74
Show member pathways
 11.68 IL6 CXCL8 CD40LG
34
Lung fibrosis 74
11.68 IL6 CXCL8 CCL2
35
IL 10 signaling pathway 67
11.67 CD40LG IL6 TLR4
36
miRNAs involvement in the immune response in sepsis 74
11.67 CXCL8 IL6 TLR4
37
Inflammatory bowel disease signaling 74
Show member pathways
 11.63 IL18 IL6 TLR2 TLR4 TLR5
38
Hepatitis C and hepatocellular carcinoma 74
11.61 IL6 CXCR1 CXCL8
39
Burn wound healing 74
11.61 TLR4 IL6 CXCR2 CXCL8 CXCL1 CCL2
40
SARS-CoV-2 innate immunity evasion and cell-specific immune response 74
11.6 CXCR2 CXCL8 CXCL1 CCL2
41
MSP-RON Signaling 64
11.56 TLR4 TLR2 IL18 CCL2
42
IL8- and CXCR2-mediated signaling events 61
Show member pathways
 11.55 CXCR2 CXCR1 CXCL8
43
Non-genomic actions of 1,25 dihydroxyvitamin D3 74
11.54 TLR4 IL6 CXCL8 CD40LG CCL2
44
Fibrin complement receptor 3 signaling pathway 74
11.49 CCL2 IL6 TIRAP TLR4
45
Interleukin-10 signaling 66
11.44 IL6 IL18 CXCL8 CXCL1 CCL2
46
Validated transcriptional targets of AP1 family members Fra1 and Fra2 61
11.4 CCL2 CXCL8 IL6
47
A-beta Uptake and Degradation 65
11.35 TLR4 CD40LG CCL2
48
Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway 74
11.32 IL6 CXCL8 CCL2
49
Immune infiltration in pancreatic cancer 74
11.27 IL6 CXCL8 CXCL1
50
Prostaglandin signaling 74
11.27 IL6 CXCL8 CXCL1 CCL2
Sources

GO Terms for Bacteriuria

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Cellular components related to Bacteriuria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Toll-like receptor 1-Toll-like receptor 2 protein complex GO:0035354 8.92 TLR2 TLR1

Biological processes related to Bacteriuria according to GeneCards Suite gene sharing:

(show all 34)
# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 10.38 CCL2 CD40LG CXCL1 CXCL8 CXCR1 CXCR2
2 defense response to Gram-positive bacterium GO:0050830 10.29 CRP IL18 IL6 TIRAP TLR2
3 chemotaxis GO:0006935 10.25 CXCR2 CXCR1 CXCL8 CXCL1 CCL2
4 positive regulation of tumor necrosis factor production GO:0032760 10.25 TLR4 TLR2 TLR1 TIRAP IL6
5 cellular response to lipopolysaccharide GO:0071222 10.25 CCL2 CXCL1 CXCL8 IL6 TLR4 TLR5
6 positive regulation of interleukin-6 production GO:0032755 10.22 TLR4 TLR2 TLR1 TIRAP IL6
7 positive regulation of chemokine production GO:0032722 10.19 TLR4 TLR2 IL6 IL18
8 neutrophil chemotaxis GO:0030593 10.19 CXCR2 CXCR1 CXCL8 CXCL1 CCL2
9 positive regulation of NF-kappaB transcription factor activity GO:0051092 10.18 TLR4 TLR2 TIRAP IL6 IL18 CD40LG
10 positive regulation of interleukin-12 production GO:0032735 10.17 TLR4 TLR2 TIRAP CD40LG
11 positive regulation of interleukin-10 production GO:0032733 10.16 CD40LG IL6 TLR2 TLR4
12 chemokine-mediated signaling pathway GO:0070098 10.16 CXCR2 CXCR1 CXCL8 CXCL1 CCL2
13 receptor internalization GO:0031623 10.14 CXCR2 CXCR1 CXCL8
14 lipopolysaccharide-mediated signaling pathway GO:0031663 10.14 TLR4 TLR2 IL18 CCL2
15 immune system process GO:0002376 10.13 TLR5 TLR4 TLR2 TLR1 TIRAP CD79A
16 positive regulation of neutrophil chemotaxis GO:0090023 10.11 TIRAP CXCR2 CXCL8
17 positive regulation of interleukin-8 production GO:0032757 10.1 IL6 TIRAP TLR1 TLR2 TLR4 TLR5
18 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 10.09 TLR4 TLR2 CCL2
19 immune response GO:0006955 10.09 TLR5 TLR4 TLR2 TLR1 IL6 IL18
20 neutrophil activation GO:0042119 10.08 IL18 CXCR2 CXCL8
21 B cell proliferation GO:0042100 10.06 TLR4 CD79A CD40LG
22 cellular response to lipoteichoic acid GO:0071223 10.05 TLR4 TLR2 TIRAP
23 toll-like receptor signaling pathway GO:0002224 10.03 TLR1 TLR2 TLR4 TLR5
24 positive regulation of toll-like receptor 2 signaling pathway GO:0034137 9.96 TLR1 TIRAP
25 MyD88-dependent toll-like receptor signaling pathway GO:0002755 9.96 TLR5 TLR4 TLR2 TLR1 TIRAP
26 positive regulation of toll-like receptor signaling pathway GO:0034123 9.95 TLR5 TLR2
27 cellular response to bacterial lipopeptide GO:0071221 9.95 TLR2 TLR1 TIRAP
28 cellular response to triacyl bacterial lipopeptide GO:0071727 9.94 TLR2 TLR1
29 positive regulation of matrix metallopeptidase secretion GO:1904466 9.93 TLR2 TLR4
30 positive regulation of cellular response to macrophage colony-stimulating factor stimulus GO:1903974 9.93 TLR4 TLR2
31 detection of triacyl bacterial lipopeptide GO:0042495 9.92 TLR2 TLR1
32 interleukin-8-mediated signaling pathway GO:0038112 9.92 CXCR2 CXCR1
33 inflammatory response GO:0006954 9.77 UMOD TLR5 TLR4 TLR2 TLR1 TIRAP
34 response to external stimulus GO:0009605 9.43 CXCL1 CXCL8 TLR1 TLR2 TLR4 TLR5

Molecular functions related to Bacteriuria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transmembrane signaling receptor activity GO:0004888 10.02 TLR5 TLR4 TLR2 TLR1 CD79A
2 lipopolysaccharide immune receptor activity GO:0001875 9.73 TLR4 TLR2
3 Toll-like receptor 2 binding GO:0035663 9.71 TLR1 TIRAP
4 interleukin-8 binding GO:0019959 9.67 CXCR2 CXCR1
5 NAD+ nucleotidase, cyclic ADP-ribose generating GO:0061809 9.63 TLR4 TLR2 TLR1
6 interleukin-8 receptor activity GO:0004918 9.56 CXCR1 CXCR2
7 NAD(P)+ nucleosidase activity GO:0050135 9.43 TLR4 TLR2 TLR1
8 cytokine activity GO:0005125 9.28 IL6 IL18 CXCL8 CXCL1 CD40LG CCL2
Sources

Sources for Bacteriuria

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2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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