Bacteriuria disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: BCT004 MIFTS: 48	Bacteriuria Categories: Nephrological diseases
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Aliases & Classifications for Bacteriuria

MalaCards integrated aliases for Bacteriuria:

Name: Bacteriuria ¹² ⁵⁴ ⁴⁴ ¹⁵ ⁷⁰

Classifications:

MalaCards categories:
Anatomical: Nephrological diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:1412

MeSH ⁴⁴ D001437

SNOMED-CT ⁶⁷ 61373006

ICD10 ³² R82.71

UMLS ⁷⁰ C0004659

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Summaries for Bacteriuria

Disease Ontology : ¹² A urinary system disease which consists of the presence of bacteria in urine.

MalaCards based summary : Bacteriuria is related to urinary tract infection and pyuria. An important gene associated with Bacteriuria is TLR4 (Toll Like Receptor 4), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Nitrofurantoin and Sulfamethoxazole have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, prostate and skin, and related phenotypes are cardiovascular system and hematopoietic system

Wikipedia : ⁷³ Bacteriuria is the presence of bacteria in urine. Bacteriuria accompanied by symptoms is a urinary tract... more...

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Related Diseases for Bacteriuria

Diseases related to Bacteriuria via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 488)

#	Related Disease	Score	Top Affiliating Genes
1	urinary tract infection	31.6	UMOD TLR4 CRP CAT
2	pyuria	31.5	IL6 CXCL8 CRP
3	acute pyelonephritis	30.8	IL6 CXCR2 CXCR1 CXCL8 CRP
4	chronic pyelonephritis	30.8	UMOD TLR4 CRP
5	pyelonephritis	30.6	UMOD TLR4 IL6 CXCR2 CXCR1 CXCL8
6	acute cystitis	30.6	UMOD TLR4 IL6 IL18 CXCL8 CXCL1
7	prosthetic joint infection	30.5	TLR4 TLR2 IL6 CRP
8	vaginitis	30.5	TLR2 IL6 CXCL8
9	cervicitis	30.3	TLR4 IL6 CXCL8
10	endocarditis	30.3	TLR2 IL6 CXCL8 CRP
11	urinary tract obstruction	30.3	UMOD CRP CCL2
12	interstitial cystitis	30.2	UMOD IL6 CXCL8
13	vesicoureteral reflux 1	30.2	UMOD CXCR1 CXCL8 CRP
14	placenta disease	30.1	IL6 CXCL8 CRP
15	cystitis	30.1	UMOD TLR4 IL6 IL18 CXCL8 CXCL1
16	hydronephrosis	30.1	IL6 CXCL8 CRP CCL2
17	endometritis	30.1	TLR4 TLR2 IL6 CXCL8 CXCL1
18	pre-eclampsia	30.1	TLR4 IL6 IL18 CXCL8 CRP
19	diarrhea	30.1	TLR4 IL6 CXCL8 CD40LG
20	vaginal discharge	30.1	IL6 CXCL8 CRP
21	klebsiella pneumonia	30.1	TLR4 TLR2 IL6 CXCL8 CXCL1 CRP
22	urethritis	30.0	TLR4 TLR2 IL6 CXCL8 CRP
23	infective endocarditis	30.0	TLR2 IL6 CRP
24	gastroenteritis	30.0	IL6 CXCL8 CRP
25	typhoid fever	30.0	TLR5 TLR4 IL6 CRP
26	liver cirrhosis	30.0	TLR4 TLR2 IL6 CXCL8 CRP
27	conjunctivitis	29.9	TLR4 IL6 CXCL8 CCL2
28	disease by infectious agent	29.8	TLR4 TLR2 IL6 IL18 CRP
29	dermatitis	29.8	TLR2 IL6 IL18 CXCL8
30	mastitis	29.8	TLR2 IL6 IL18 CXCL8
31	allergic disease	29.8	TLR4 TLR2 IL6 IL18 CXCR1 CXCL8
32	pericarditis	29.7	IL6 CXCL8 CRP
33	bacterial infectious disease	29.7	TLR5 TLR4 TLR2 TLR1 IL6 IL18
34	sickle cell anemia	29.7	IL6 CXCL8 CRP CD40LG
35	endophthalmitis	29.7	TLR2 PRF1 IL6 CXCL8 CRP
36	cholangitis	29.7	TLR4 IL6 CXCL8 CRP
37	chronic kidney disease	29.7	UMOD TLR4 IL6 IL18 CRP CCL2
38	toxic shock syndrome	29.7	TLR4 TLR2 IL6 CXCL8 CRP CD40LG
39	peripheral nervous system disease	29.7	TLR4 IL6 CXCL8 CRP CCL2
40	end stage renal disease	29.6	UMOD IL6 CRP CCL2
41	chorioamnionitis	29.6	TLR4 IL6 IL18 CXCL8 CRP CCL2
42	urticaria	29.6	IL6 IL18 CXCL8 CRP
43	osteomyelitis	29.6	TLR4 TLR2 IL6 CXCL8 CRP CCL2
44	iga glomerulonephritis	29.6	IL6 CD79A CD40LG CCL2
45	leprosy 3	29.6	TLR4 TLR2 TLR1 IL6 CXCL8 CCL2
46	bacterial sepsis	29.6	TLR4 TLR2 IL6 IL18 CXCL8 CRP
47	salmonellosis	29.6	TLR5 TLR4 TLR2 IL6 IL18 CXCL8
48	kawasaki disease	29.6	IL6 IL18 CRP CCL2
49	peripheral vascular disease	29.5	IL6 IL18 CRP CCL2
50	appendicitis	29.5	TLR4 IL6 CXCL8 CRP CCL2

Graphical network of the top 20 diseases related to Bacteriuria:

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Symptoms & Phenotypes for Bacteriuria

MGI Mouse Phenotypes related to Bacteriuria:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	cardiovascular system	MP:0005385	10.22	ARSB ASB1 CD40LG CRP CXCR2 IL18
2	hematopoietic system	MP:0005397	10.17	ARSB ASB1 CD40LG CD79A CXCR1 CXCR2
3	cellular	MP:0005384	10.15	ARSB CAT CD40LG CD79A CXCR2 IL18
4	homeostasis/metabolism	MP:0005376	10.13	ARSB CAT CD40LG CD79A CRP CXCR1
5	adipose tissue	MP:0005375	10.03	ARSB CXCR2 IL18 IL6 TLR2 TLR4
6	immune system	MP:0005387	10.03	ASB1 CCL2 CD40LG CD79A CRP CXCR2
7	neoplasm	MP:0002006	9.5	CAT CD79A CXCR2 IL6 PRF1 TLR2
8	renal/urinary system	MP:0005367	9.23	ARSB CD40LG CD79A CXCR2 IL6 TLR2

Sources

Drugs & Therapeutics for Bacteriuria

Drugs for Bacteriuria (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 62)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Nitrofurantoin

Approved, Vet_approved

Phase 4

67-20-9

5353830

Sulfamethoxazole

Approved

Phase 4

723-46-6

5329

Trimethoprim

Approved, Vet_approved

Phase 4

738-70-5

5578

Ciprofloxacin

Approved, Investigational

Phase 4

85721-33-1

2764

Cephalexin

Approved, Investigational, Vet_approved

Phase 4

15686-71-2

27447

Fosfomycin

Approved

Phase 4

23155-02-4

446987

Amoxicillin

Approved, Vet_approved

Phase 4

26787-78-0

33613

Povidone

Approved

Phase 4

9003-39-8

131751496

Povidone-iodine

Approved

Phase 4

25655-41-8

Iodine

Approved, Investigational

Phase 4

7553-56-2

807

Cadexomer iodine

Experimental

Phase 4

94820-09-4

Dermatologic Agents

Phase 4

Cytochrome P-450 Enzyme Inhibitors

Phase 4

Pharmaceutical Solutions

Phase 4

Folic Acid Antagonists

Phase 4

Antiparasitic Agents

Phase 4

Antimalarials

Phase 4

Antiprotozoal Agents

Phase 4

Anti-Infective Agents, Local

Phase 4

Plasma Substitutes

Phase 4

Blood Substitutes

Phase 4

Ofloxacin

Approved

Phase 3

82419-36-1

4583

Levofloxacin

Approved, Investigational

Phase 3

100986-85-4

149096

Lomefloxacin

Approved, Investigational

Phase 3

98079-51-7

3948

Proanthocyanidin

Phase 3

Anthocyanidin

Phase 3

Procyanidin

Phase 3

4852-22-6

147299

Cranberry

Approved, Investigational

Phase 2

Antitubercular Agents

Phase 2

Methenamine

Approved, Vet_approved

Phase 1

100-97-0

4101

Nitric Oxide

Approved

Phase 1

10102-43-9

145068

Methenamine hippurate

Phase 1

Methenamine mandelate

Phase 1

Anti-Asthmatic Agents

Phase 1

Vasodilator Agents

Phase 1

Respiratory System Agents

Phase 1

Neurotransmitter Agents

Phase 1

Antioxidants

Phase 1

Endothelium-Dependent Relaxing Factors

Phase 1

Bronchodilator Agents

Phase 1

Protective Agents

Phase 1

Cefazolin

Approved

25953-19-9

33255 656510

Ampicillin

Approved, Vet_approved

69-53-4

6249

Sulbactam

Approved

68373-14-8

Tobramycin

Approved, Investigational

32986-56-4

5496 36294

Chlorhexidine

Approved, Vet_approved

55-56-1

2713 9552079

Grape

Approved

Sodium citrate

Approved, Investigational

68-04-2

Zinc

Approved, Investigational

7440-66-6

32051

Allantoin

Approved

97-59-6

204

Interventional clinical trials:

(show top 50) (show all 62)

#	Name	Status	NCT ID	Phase	Drugs
1	Comparison of the Effect of Applying Povidone-iodine and Chlorhexidine Solutions for Perinea Washing on Bacteriuria Rate and Type in Patients With Urinary Catheter in Intensive Care Unit	Unknown status	NCT02032394	Phase 4	Povidone-iodine;Chlorhexidine;Normal saline
2	Clinical Impact of Bacteriuria on Chronic Inflammation in Asymptomatic Hemodialysis Patients	Unknown status	NCT01570556	Phase 4
3	The Impact of Antimicrobial Treatment for Asymptomatic Bacteriuria in Renal Transplant Patients	Unknown status	NCT02113774	Phase 4
4	The Bacteriuria in Renal Transplantation (BiRT) Study: A Prospective, Randomized, Parallel-group, Multicenter, Open-label, Superiority Trial Comparing Antibiotics Versus no Treatment in the Prevention of Symptomatic Urinary Tract Infection in Kidney Transplant Recipients With Asymptomatic Bacteriuria	Completed	NCT01871753	Phase 4
5	Management of Sub-Clinical Bacteriuria in Pregnancy: A Feasibility Trial	Completed	NCT03275623	Phase 4	Antibiotic
6	Use of Antibiotic Prophylaxis on Urethral Catheter Withdrawal: A Randomized Double-Blind Placebo-Controlled Trial	Completed	NCT00126698	Phase 4	trimethoprim-sulfamethoxazole;ciprofloxacin
7	Fosfomycin-Trometamol in Urinary Tract Infection Prophylaxis After Kidney Transplantation. Randomized Controlled Trial.	Completed	NCT01820897	Phase 4	Fosfomycin-Trometamol;Sulfamethoxazole trimethoprim
8	Perioperative Disodium Fosfomycin in the Prophylaxis of Urinary Tract Infection in Kidney Transplant Recipients. Controlled Clinical Trial (PERIFOS Trial)	Completed	NCT03235947	Phase 4	Fosfomycin disodium;Trimethoprim / Sulfamethoxazole;Intravenous placebo
9	A Randomized Trial of Betadine Bladder Irrigations vs. Standard of Care Prior to Indwelling Catheter Removal to Reduce Bacteriuria and Catheter-Associated Urinary Tract Infections	Terminated	NCT03447639	Phase 4	Povidone-iodine irrigation
10	Enhancing Nutrition and Antenatal Infection Treatment for Maternal and Child Health in Amhara Region, Ethiopia	Withdrawn	NCT04171388	Phase 4	Azithromycin 500 mg;Placebo oral tablet 500 mg
11	A Multicenter, Randomized Study To Compare The Safety And Efficacy Of Oral Levofloxacin With That Of Lomefloxacin HCl In The Treatment Of Complicated Urinary Tract Infections In Adults	Completed	NCT00258102	Phase 3	Levofloxacin
12	A Multicenter, Double-Blind, Randomized Study To Compare The Safety And Efficacy Of Oral Levofloxacin With That Of Ciprofloxacin HCl In The Treatment Of Complicated Urinary Tract Infections In Adults	Completed	NCT00258089	Phase 3	Levofloxacin
13	A Randomized, Controlled Trial of Cranberry Capsules for UTI Prevention in Nursing Home Residents	Completed	NCT01691430	Phase 3
14	Empirical Use of Fosfomycin as a Single Dose Oral Treatment of Asymptomatic Bacteriuria	Unknown status	NCT03548129	Phase 2	phosphomycin;Culture specific antibiotic therapy
15	A Phase IIa Open Label Study to Evaluate the Safety and Antimicrobial Effects of NVC-422 on Bacteriuria in Chronically Catheterized Subjects	Completed	NCT00781339	Phase 2	sodium 2-(dichloroamino)-2-methylpropane-1-sulfonate monohydrate
16	A Pilot Randomized Control Study of Shortening Antibiotic Treatment Duration For Asymptomatic Bacteriuria Within A Month After Kidney Transplantation	Completed	NCT02575495	Phase 2	7 days course of antibiotic treatment;14 days course of antibiotic treatment
17	Prevention of Nosocomial Escherichia Coli Infections After Placement of an Indwelling Catheter During Pelvic Surgery: a Randomized, Prospective, Double Blind Study for the Evaluation of Cranberry (Vaccinium Macrocarpon) Gel Capsules	Completed	NCT01114347	Phase 2
18	Bacteriuria Eradication Through Probiotics	Unknown status	NCT00717600	Phase 1
19	Pilot Study: Dosing Study of Cranberry Capsules for the Prevention of Bacteriuria in Nursing Home Residents	Completed	NCT01033383	Phase 1
20	Cranberry for Prevention of Bacteriuria in Pregnancy	Completed	NCT00093938	Phase 1	Cranberry juice
21	Prospective, Phase I, Single-Center, Evaluation of the Safety and Tolerability of Nitric Oxide Impregnated Urinary Catheters in Patients Undergoing Radical Prostatectomy	Completed	NCT02277171	Phase 1
22	Retained Urine Volume and Bacteriuria in Traditional Versus Vented Urine Drainage Systems	Withdrawn	NCT02052674	Phase 1
23	Intraoperative One-Time Catheterization in Short Gynecologic Procedures and Its Potential Effect on Symptomatic and Asymptomatic Bacteriuria	Unknown status	NCT01926756
24	Antibiotic Treatment Versus no Therapy in Kidney Transplant Recipients With Asymptomatic Bacteriuria. A Prospective Randomized Study.	Unknown status	NCT01771432		Antibiotic treatment
25	Comparison of Verbal Versus Video Instruction in the Collection of Clean Catch Urine in Pregnant Women Undergoing Testing for Asymptomatic Bacturia: Randomized Control Trial	Unknown status	NCT03658356
26	Effect of a Nurse-centered Multimodal Intervention on Prescribing Antibiotics in Nursing Home: A Randomized Cluster Study	Unknown status	NCT03180983
27	Asymptomatic Bacteriuria & Risk of Urinary Tract Infection in Renal Transplants	Unknown status	NCT01349738		Antibiotic
28	a Symptomatic Bacteriuria in Pregnant Females	Unknown status	NCT03499561
29	Effectiveness of Three Different Times of Starting Antibiotic Prophylaxis in Patients With Asymptomatic Bacteriuria Scheduled for Urological Surgery. A Randomized Multicentric Clinical Trial	Unknown status	NCT03269604
30	Health Care-associated Bacteriuria in Geriatric Wards in Strasbourg's University Hospital : a Comparative Study of Bacterial Ecology Between 2003, 2007 and 2017	Unknown status	NCT03577769
31	Postnatal Prevalence of Bacteriuria in Women With Catheter Versus no Catheter in Labour: a Prospective Cohort Study	Unknown status	NCT03914144
32	Incidence of Symptomatic and Asymptomatic Bacteriuria After Urodynamic Study With or Without Antibiotic Prophylaxis in Women With Urinary Incontinence	Completed	NCT03106103
33	Guideline Implementation to Decrease Inappropriate Bacteriuria Treatment	Completed	NCT01052545
34	Outcomes of Urinary Tract Infection Management by Pharmacists	Completed	NCT03184818
35	Effect of Systematic Search and Antimicrobial Treatment of Asymptomatic Bacteriuria in Kidney Transplant Recipients in the Incidence of Acute Pyelonephritis: a Pragmatic Prospective Randomized Controlled Study.	Completed	NCT02373085
36	Rapid Urinary Tract Infection Diagnosis and Real-time Antimicrobial Stewardship Decision Support - Accuracy and Effect on Antibiotic Consumption	Completed	NCT03256825
37	Modified Reporting of Positive Urine Cultures Collected From Indwelling Catheters, a Randomized Controlled Trial	Completed	NCT03488355
38	Partnership to Enhance Antimicrobial Use in Resource-Limited Settings (PEARL): An Assessment of Need and Feasibility of Antimicrobial Stewardship Programs	Completed	NCT03382470
39	Open Prospective Study on Reduction of Bacteriuria Following Bladder Irrigation With Chlorhexidine	Completed	NCT01782404
40	Restricted Reporting for Positive Urine Cultures Randomized Controlled Trial	Completed	NCT02797613
41	Effectiveness of Cranberry Ingestion on Bacterial Adhesion: Adjunct to Pilot Study of Daily Cranberry Ingestion of Cranberry Juice for the Prevention of Asymptomatic Bacteriuria in Pregnancy	Completed	NCT00506025
42	Safety and Effectiveness of a Laboratory Intervention to Effectively NOT Treat Asymptomatic Bacteriuria (SALIENT-A)	Completed	NCT03445312
43	The Frequency of Leukocytes and Nitrites in the Urine of Healthy Adults	Completed	NCT04055675
44	Assessment of Infection Control, Practice Efficiency, and Health Economics of Sheathed Versus Standard Flexible Cystoscopy	Completed	NCT02922868
45	Randomized Clinical Trial on the Safety and Efficacy of Lactobacillus Reuteri DSM 16666/ATCC 55845 & Lactobacillus Reuteri DSM 17938 for Treatment of Pregnant Women With Asymptomatic Bacteriuria or Uncomplicated Acute Cystitis	Completed	NCT03362697		Antibiotics
46	Induced Asymptomatic E. Coli 83972 Bacteriuria in Patients With Recurrent Urinary Tract Infections and Bladder Dysfunction- is There a Protective Effect Against Recurrent Symptomatic Infections? A Blinded Placebo Controlled Cross-over Study.	Completed	NCT00927316
47	Avoiding Bacterial Contamination of Clean Catch Urine Cultures in Ambulatory Patients in the Emergency Department	Completed	NCT03131609
48	Modified Reporting of Positive Urine Cultures Collected From Long Term Care, a Randomized Controlled Trial	Completed	NCT03554603
49	Behavioral Economics Applications to Geriatrics Leveraging EHRs	Completed	NCT03704389
50	Screening and Treatment of Asymptomatic Bacteriuria in the First Two Months After Kidney Transplant. Randomized Control Trial	Recruiting	NCT04333602

Search NIH Clinical Center for Bacteriuria

Inferred drug relations via UMLS ⁷⁰ / NDF-RT ⁵¹ :

Methenamine

methenamine hippurate

methenamine mandelate

METHENAMINE SULFOSALICYLATE

Cochrane evidence based reviews: bacteriuria

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Genetic Tests for Bacteriuria

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Anatomical Context for Bacteriuria

MalaCards organs/tissues related to Bacteriuria:

⁴⁰

Spinal Cord, Prostate, Skin, Colon, Kidney, Cervix, Neutrophil

Sources

Publications for Bacteriuria

Articles related to Bacteriuria:

(show top 50) (show all 6048)

#	Title	Authors	PMID	Year
1	Comparison of urinary proteins in calcium stone formers and healthy individuals: a case-control study. ⁶¹ ⁵⁴	Pourmand G...Nourijelyani K	16493220	2006
2	Urinary Tamm-Horsfall protein and citrate: a case-control study of inhibitors and promoters of calcium stone formation. ⁵⁴ ⁶¹	Pourmand G...Shekarpour L	17629875	2005
3	Catheter-obtained, Enterococcus and Proteus positive urine cultures may represent mostly contamination or asymptomatic bacteriuria in infants <90 days. ⁶¹	Gatt D...Ben-Shimol S	33620253	2021
4	UriSed 3 PRO automated microscope in screening bacteriuria at region-wide laboratory organization. ⁶¹	Kouri T...Patari-Sampo A	33549597	2021
5	Antimicrobial Prophylaxis for Postoperative Urinary Tract Infections in Transurethral Resection of Bladder Tumors: A Systematic Review and Meta-Analysis. ⁶¹	Bausch K...Seifert HH	33284673	2021
6	Clinical and microbiological characterization of subclinical bacteriuria and sporadic bacterial cystitis in dogs with spontaneous hypercortisolism. ⁶¹	Machado L...Poppl AG	33609989	2021
7	Factors associated with positive urine cultures in cats with subcutaneous ureteral bypass system implantation. ⁶¹	Pennington CE...Geddes RF	32840421	2021
8	Risk factors of febrile urinary tract infections following retrograde intrarenal surgery for renal stones. ⁶¹	Kim DS...Lee SH	33787599	2021
9	Evaluation of the detection ability of uropathogen morphology and vaginal contamination by the Atellica UAS800 automated urine microscopy analyzer and its effectiveness. ⁶¹	Nakamura A...Yamanishi H	33426721	2021
10	Diagnostic accuracy of a point-of-care test using voided urine samples for detection of bacteriuria in dogs with signs of lower urinary tract disease. ⁶¹	Grant DC...Corrigan VK	33527463	2021
11	Antibiotics versus no therapy in kidney transplant recipients with asymptomatic bacteriuria (BiRT): a pragmatic, multicentre, randomized, controlled trial. ⁶¹	Coussement J...Bacteriuria in Renal Transplantation (BiRT) study group	32919076	2021
12	Assessment and management of urinary tract infections in aged care facilities. ⁶¹	Khatri D...Burrows J	33135312	2021
13	A Case-Control Study on the Association between Salmonella Bacteriuria and Cystoscopy. ⁶¹	Yeung EYH	33804416	2021
14	A prospective study on the pathogenesis of catheter-associated bacteriuria in critically ill patients. ⁶¹	Aumeran C...Lautrette A	33752594	2021
15	Asymptomatic bacteriuria in kidney transplant recipients: to treat or not to treat-that is the question. ⁶¹	Sabe N...Carratala J	33276138	2021
16	The utility of Amies charcoal bacteriology swabs for storage of canine urine prior to culture. ⁶¹	Olivares G...Warland J	33274769	2021
17	Determining the Safety Threshold for the Passage of a Ureteral Access Sheath in Clinical Practice Using a Purpose-Built Force Sensor. ⁶¹	Tapiero S...Clayman RV	33780267	2021
18	High dose versus low dose standardized cranberry proanthocyanidin extract for the prevention of recurrent urinary tract infection in healthy women: a double-blind randomized controlled trial. ⁶¹	Babar A...Dodin S	33757474	2021
19	Impact of Treating Asymptomatic Bacteriuria in Kidney Transplant Recipients: A Prospective Cohort Study. ⁶¹	Fontsere S...Cordero E	33671718	2021
20	Asymptomatic Bacteriuria (ABU) in Elderly: Prevalence, Virulence, Phylogeny, Antibiotic Resistance and Complement C3 in Urine. ⁶¹	Leihof RF...Frimodt-Moller N	33672892	2021
21	Uropathogenic Escherichia coli in India-an Overview on Recent Research Advancements and Trends. ⁶¹	Ghosh A...Mukherjee M	33595784	2021
22	Diagnostic stewardship programme for urine culture: impact on antimicrobial prescription in a multi-centre cohort. ⁶¹	Lee ALH...Lai RWM	33181278	2021
23	Efficacy and safety of oral fosfomycin for asymptomatic bacteriuria in kidney transplant recipients: Results from a Spanish multicenter cohort. ⁶¹	Ruiz-Ruigomez M...REIPI, REDinREN, and GESITRA-IC/SEIMC.	33558295	2021
24	Characteristics of Asymptomatic Bacteriuria in Diabetes Mellitus Patients: A Retrospective Observational Study. ⁶¹	Asghar MS...Ali A	33791179	2021
25	A Comparison of Periurethral Cleaning between Normal Saline and Savlon Solutions before Indwelling Urinary Catheterization in Reducing Catheter-Associated Bacteriuria: A Randomized Controlled Study. ⁶¹	Khahakaew S...Suankratay C	33636356	2021
26	Accuracy of urine flow cytometry and urine test strip in predicting relevant bacteriuria in different patient populations. ⁶¹	Gehringer C...Egli A	33632129	2021
27	Changes in Bacterial Spectrum and Resistance Patterns Over Time in the Urine of Patients with Neurogenic Lower Urinary Tract Dysfunction Due to Spinal Cord Injury. ⁶¹	Pannek J...Wollner J	33567445	2021
28	Antibiotic prescribing for adult bacteriuria and pyuria in community hospital emergency departments. ⁶¹	Veillette JJ...Vento TJ	33326910	2021
29	Prevalence of, and factors associated with, positive urine cultures in hyperthyroid cats presenting for radioiodine therapy. ⁶¹	Keebaugh AE...Panciera DL	32478636	2021
30	Experiences of Veterans with Spinal Cord Injury Related to Annual Urine Screening and Antibiotic use for Urinary Tract Infections. ⁶¹	Hines-Munson C...Skelton F	33543579	2021
31	Rising prevalence of multidrug-resistant uropathogenic bacteria from urinary tract infections in pregnant women. ⁶¹	Asmat U...Malik A	33603638	2021
32	Antibiotics for culture-positive asymptomatic bacteriuria in pregnant women can prevent pyelonephritis. ⁶¹	Kwofie K...Wolfson AB	33550633	2021
33	Deimplementation strategy to reduce overtreatment of asymptomatic bacteriuria: a study protocol for a stepped-wedge cluster randomised trial. ⁶¹	van Horrik TM...Laan BJ	33563619	2021
34	Renal abscess caused by Panton-Valentine leukocidin-producing Staphylococcus aureus: report of an unusual case and review of the literature. ⁶¹	Conan PL...Flamarion E	33307902	2021
35	A survey of adult and pediatric urologists on current practice in antibiotic prophylaxis for ureteral stent removal. ⁶¹	Berrondo C...Shnorhavorian M	33246833	2021
36	Indwelling catheterization, renal stones, and hydronephrosis are risk factors for symptomatic Staphylococcus aureus-related urinary tract infection. ⁶¹	Kitano H...Ohge H	32363449	2021
37	Urodynamic effectiveness of a beta-3 adrenoreceptor agonist (vibegron) for a pediatric patient with anticholinergic-resistant neurogenic detrusor overactivity: a case report. ⁶¹	Kato T...Hayashi Y	33602290	2021
38	IATROGENIC URETERAL INJURY TREATMENT WITH BIODEGRADABLE-ANTIREFLUX HEPARIN COATED URETERAL STENT. ANIMAL MODEL COMPARATIVE STUDY. ⁶¹	Soria F...Sanchez Margallo FM	33626973	2021
39	Comparative assessment of biodegradable-antireflux heparine coated ureteral stent: animal model study. ⁶¹	Soria F...Sanchez-Margallo FM	33639905	2021
40	Risk factors for urinary bacterial growth in dogs with congenital portosystemic shunts: 66 cases (1997-2019). ⁶¹	Tinoco-Najera A...Lidbury JA	33491792	2021
41	Safety, effectiveness and sustainability of a laboratory intervention to de-adopt culture of midstream urine samples among hospitalized patients. ⁶¹	Mozafarihashjin M...McGeer A	32873350	2021
42	Biofilm-Producing Bacteria and Risk Factors (Gender and Duration of Catheterization) Characterized as Catheter-Associated Biofilm Formation. ⁶¹	Gunardi WD...Safari D	33688348	2021
43	Optimal timing to screen for asymptomatic bacteriuria during pregnancy: first vs. second trimester. ⁶¹	Langermans LM...Faron G	33554579	2021
44	Antibiotic prophylaxis for urinary catheter manipulation following arthroplasty: a systematic review. ⁶¹	Roberts T...Hing CB	33475215	2021
45	Prevalence, clinical profile and follow up of asymptomatic bacteriuria in patients with type 2 diabetes-prospective case control study in Srinagar, India. ⁶¹	Laway BA...Fomda BA	33601179	2021
46	The frequency of urinary tract infections and the value of antiseptics in community-dwelling people who undertake intermittent urinary catheterization: A systematic review. ⁶¹	Mitchell BG...Kiernan M	33485920	2021
47	Antibiotic prophylaxis for urodynamic testing in women: a systematic review. ⁶¹	Benseler A...McDermott CD	32845398	2021
48	Antimicrobial Resistance among Pregnant Women with Urinary Tract Infections Attending Antenatal Clinic at Levy Mwanawasa University Teaching Hospital (LMUTH), Lusaka, Zambia. ⁶¹	Yeta KI...Jacobs C	33747088	2021
49	Prophylactic Antibiotics for Urinary Tract Infections after Urodynamic Studies: A Meta-Analysis. ⁶¹	Wu XY...Du GH	33728337	2021
50	Antimicrobial use for asymptomatic bacteriuria-First, do no harm. ⁶¹	Shpunt Y...Marchaim D	32787996	2021

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Genes for Bacteriuria

Genes related to Bacteriuria (0 elite genes):

(show all 22)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubMed IDs
1	TLR4	Toll Like Receptor 4	Protein Coding	13.6	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
2	CXCR1	C-X-C Motif Chemokine Receptor 1	Protein Coding	13.05	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
3	CXCL8	C-X-C Motif Chemokine Ligand 8	Protein Coding	12.73	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
4	IL6	Interleukin 6	Protein Coding	12.68	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
5	TLR5	Toll Like Receptor 5	Protein Coding	12.64	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
6	TLR2	Toll Like Receptor 2	Protein Coding	12.38	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
7	UMOD	Uromodulin	Protein Coding	12.11	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁴	16493220 17629875
8	TLR1	Toll Like Receptor 1	Protein Coding	11.87	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
9	TIRAP	TIR Domain Containing Adaptor Protein	Protein Coding	11.78	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
10	CXCL1	C-X-C Motif Chemokine Ligand 1	Protein Coding	11.68	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
11	CCL2	C-C Motif Chemokine Ligand 2	Protein Coding	11.25	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
12	CXCR2	C-X-C Motif Chemokine Receptor 2	Protein Coding	11.21	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
13	PRF1	Perforin 1	Protein Coding	11.11	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
14	IL18	Interleukin 18	Protein Coding	10.33	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
15	CRP	C-Reactive Protein	Protein Coding	6.96	DISEASES inferred ¹⁵
16	ARSB	Arylsulfatase B	Protein Coding	6.64	DISEASES inferred ¹⁵
17	ASB1	Ankyrin Repeat And SOCS Box Containing 1	Protein Coding	6.45	DISEASES inferred ¹⁵
18	CAT	Catalase	Protein Coding	6.43	GeneCards inferred via : Publications (show sections)
19	CD40LG	CD40 Ligand	Protein Coding	6.43	GeneCards inferred via : Publications (show sections)
20	CD79A	CD79a Molecule	Protein Coding	6.43	GeneCards inferred via : Publications (show sections)
21	H2AC18	H2A Clustered Histone 18	Protein Coding	6.42	DISEASES inferred ¹⁵ ¹⁵
22	ALB	Albumin	Protein Coding	6.24	DISEASES inferred ¹⁵

Sources

Variations for Bacteriuria

Sources

Expression for Bacteriuria

Search GEO for disease gene expression data for Bacteriuria.

Sources

Pathways for Bacteriuria

Pathways related to Bacteriuria according to GeneCards Suite gene sharing:

(show all 50)

#	Super pathways	Score	Top Affiliating Genes
1	Innate Immune System ⁶⁵ Show member pathways Immune System ⁶⁵ Neutrophil degranulation ⁶⁵	13.7	TLR5 TLR4 TLR2 TLR1 TIRAP IL6
2	PEDF Induced Signaling ⁶³ Show member pathways all-trans-Retinoic Acid Signaling in Brain ⁶³ Cytokine-cytokine receptor interaction ³⁶ Endothelin-1 Signaling Pathway ⁶³ Glucocorticoid Receptor Signaling ⁶³ IL-6 Pathway ⁶³ MIF Mediated Glucocorticoid Regulation ⁶³ MIF Regulation of Innate Immune Cells ⁶³ NFAT Signaling and Lymphocyte Interactions ⁶³ PGC1Alpha Pathway ⁶³ RAR-Gamma-RXR-Alpha Degradation ⁶³ STAT3 Pathway ⁶³	13.69	TLR4 IL6 IL18 CXCR2 CXCR1 CXCL8
3	PAK Pathway ⁶³ Show member pathways Antioxidant Action of Vitamin-C ⁶³ Epithelial Adherens Junctions ⁶³	13.33	IL6 IL18 CXCR2 CXCR1 CXCL8 CXCL1
4	Akt Signaling ⁶³ Show member pathways p38 Signaling ⁶³ Tec Kinases Signaling ⁶³	13.28	TLR5 TLR4 TLR2 TLR1 TIRAP IL6
5	Toll-like Receptor Signaling Pathway ³⁶ ¹ Show member pathways Chagas disease ³⁶ Hepatitis B ³⁶ Hepatitis C ³⁶ Lipid and atherosclerosis ³⁶ Regulation of toll-like receptor signaling pathway ¹	13.14	TLR5 TLR4 TLR2 TLR1 TIRAP IL6
6	Human cytomegalovirus infection ³⁶ Show member pathways Human immunodeficiency virus 1 infection ³⁶ Kaposi sarcoma-associated herpesvirus infection ³⁶	12.98	TLR4 TLR2 IL6 CXCR2 CXCL8 CXCL1
7	Measles ³⁶ Show member pathways Epstein-Barr virus infection ³⁶ Influenza A ³⁶	12.85	TLR4 TLR2 IL6 IL18 CXCL8 CCL2
8	Salmonella infection (KEGG) ³⁶ Show member pathways Pathogenic Escherichia coli infection ³⁶	12.79	TLR5 TLR4 TLR2 TIRAP IL6 IL18
9	Toll-Like receptor Signaling Pathways ⁶⁴ Show member pathways IL-1 Family Signaling Pathways ⁶⁴ Immune response IL-1 signaling pathway ²³ Immune response TLR3 and TLR4 induce TICAM1-specific signaling pathway ²³ Inflammasome Activation Pathways ⁶⁴ Mucin expression in CF via TLRs, EGFR signaling pathways ²³ NOD-like Receptor Signaling Pathways ⁶⁴	12.75	TLR5 TLR4 TLR2 TLR1 TIRAP IL6
10	NF-KappaB Family Pathway ⁶³ Show member pathways NF-KappaB (p50-p65) Pathway ⁶³	12.74	TLR5 TLR4 TLR2 TLR1 IL6 CD40LG
11	T cell receptor signaling pathway ³⁶ Show member pathways PD-L1 expression and PD-1 checkpoint pathway in cancer ³⁶ T-Cell antigen Receptor (TCR) Signaling Pathway ¹ T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection ¹	12.63	TLR4 TLR2 TIRAP IL6 CD40LG
12	TRAF Pathway ⁶³ Show member pathways 14-3-3 Induced Apoptosis ⁶³ TNF Superfamily Pathway ⁶³ Toll-Like Receptors Pathway ⁶³	12.63	TLR5 TLR4 TLR2 TLR1 TIRAP CD40LG
13	Th17 cell differentiation ³⁶ Show member pathways IL-22 Pathway ⁶³ Immune response IL-22 signaling pathway ²³ Inflammatory bowel disease ³⁶ Th1 and Th2 cell differentiation ³⁶	12.62	TLR5 TLR4 TLR2 IL6 IL18
14	NF-kappaB Signaling ⁴	12.6	TLR2 TLR1 CD79A CD40LG CCL2
15	VEGF Pathway (Qiagen) ⁶³ Show member pathways CCKBR-Gastrin Stimulated Signaling ⁶³ Development VEGF-family signaling ²³ Neurophilin interactions with VEGF and VEGFR ⁶⁵ VEGF Family Ligands and Receptor Interactions ⁶³	12.45	TLR5 TLR4 TLR2 TLR1 TIRAP
16	Shigellosis ³⁶	12.4	TLR5 TLR4 IL18 CXCL8
17	IL-17 Family Signaling Pathways ⁶⁴ Show member pathways IL17 signaling pathway ¹ IL-17 signaling pathway ³⁶ Interleukin-17 signaling ⁶⁵ Mucin expression in CF via IL-6, IL-17 signaling pathways ²³	12.39	TLR5 TLR2 IL6 CXCL8 CXCL1 CCL2
18	Chemokine Superfamily Pathway: Human/Mouse Ligand-Receptor Interactions ⁶⁴ Show member pathways Chemokine receptors bind chemokines ⁶⁵ Viral protein interaction with cytokine and cytokine receptor ³⁶	12.36	IL6 IL18 CXCR2 CXCR1 CXCL8 CXCL1
19	Folate Metabolism ¹ Show member pathways Selenium Micronutrient Network ¹ thioredoxin pathway ¹ Vitamin B12 Metabolism ¹	12.34	IL6 CRP CCL2 CAT
20	Toll Comparative Pathway ⁶³ Show member pathways IL-1 Pathway ⁶³ Immune response MIF in innate immunity response ²³ iNOS Signaling ⁶³ TLR-TRIF Pathway ⁶³	12.31	TLR4 TIRAP IL6 CXCL8
21	NOD-like receptor signaling pathway ³⁶	12.28	TLR4 IL6 IL18 CXCL8 CXCL1 CCL2
22	Diseases associated with the TLR signaling cascade ⁶⁵ Show member pathways Diseases of Immune System ⁶⁵ Interleukin-1 Induced Activation of NF-kappa-B ¹ IRAK1 recruits IKK complex ⁶⁵ IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation ⁶⁵ IRAK4 deficiency (TLR2/4) ⁶⁵ IRAK4 deficiency (TLR5) ⁶⁵ MyD88 deficiency (TLR2/4) ⁶⁵ MyD88 deficiency (TLR5) ⁶⁵ Simplified Depiction of MYD88 Distinct Input-Output Pathway ¹ TLR4 Signaling and Tolerance ¹ Toll-like Receptor Signaling ¹	12.28	TLR5 TLR4 TLR2 TLR1 TIRAP IL6
23	Tuberculosis ³⁶	12.27	TLR4 TLR2 TLR1 TIRAP IL6 IL18
24	Colorectal Cancer Metastasis ⁶³	12.24	TLR5 TLR4 TLR2 TLR1 IL6
25	Bacterial infections in CF airways ²³ Show member pathways IL-1 beta-dependent CFTR expression ²³ Immune response Bacterial infections in normal airways ²³ Immune response TLR signaling pathways ²³	12.19	TLR5 TLR4 TLR2 TLR1 TIRAP IL6
26	Yersinia infection ³⁶	12.15	TLR4 IL6 IL18 CXCL8 CCL2
27	Spinal Cord Injury ¹	12.08	TLR4 IL6 CXCL8 CXCL1 CCL2
28	MAPK Pathway ⁶⁹ Show member pathways Toll-like Receptor Pathway ⁶⁹	12.07	TLR5 TLR4 TLR2 TLR1
29	Interleukin-4 and 13 signaling ⁶⁵	12.02	IL6 IL18 CXCL8 CCL2
30	NF-kappa B signaling pathway ³⁶	12.01	TLR4 TIRAP CXCL8 CXCL1 CD40LG
31	Amoebiasis ³⁶	11.99	TLR4 TLR2 IL6 CXCL8 CXCL1
32	Cytokine production by Th17 cells in CF (Mouse model) ²³ Show member pathways Cytokine production by Th17 cells in CF ²³	11.92	TLR4 IL6 CXCL8 CXCL1
33	Th17 Differentiation Pathway ⁶⁴ Show member pathways IL-21 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types ⁶⁴	11.92	TLR5 TLR4 TLR2 TLR1 IL6
34	Phagocytosis of Microbes ⁶³	11.88	TLR5 TLR4 TLR2 TLR1
35	Pertussis ³⁶	11.82	TLR4 TIRAP IL6 CXCL8
36	Rheumatoid arthritis ³⁶	11.77	TLR4 TLR2 IL6 IL18 CXCL8 CXCL1
37	IgA-Producing B Cells in the Intestine ⁶⁴	11.74	TLR5 TLR4 TLR2 IL6 CD40LG
38	Th1 Differentiation Pathway ⁶⁴ Show member pathways IL27-mediated signaling events ¹	11.73	TLR5 TLR4 TLR2 TLR1 IL6 IL18
39	Photodynamic therapy-induced NF-kB survival signaling ¹ Show member pathways Immune response MIF-mediated glucocorticoid regulation ²³	11.68	IL6 CXCL8 CD40LG
40	Lung fibrosis ¹	11.67	IL6 CXCL8 CCL2
41	MSP-RON Signaling ⁶³	11.59	TLR4 TLR2 IL18 CCL2
42	Hepatitis C and Hepatocellular Carcinoma ¹	11.58	IL6 CXCR1 CXCL8
43	Interleukin-10 signaling ⁶⁵	11.58	IL6 IL18 CXCL8 CXCL1 CCL2
44	Validated transcriptional targets of AP1 family members Fra1 and Fra2 ¹	11.38	IL6 CXCL8 CCL2
45	A-beta Pathways: Uptake and Degradation ⁶⁴	11.35	TLR4 CD40LG CCL2
46	IL1 and megakaryocytes in obesity ¹	11.26	TLR2 TLR1 IL18 CCL2
47	Legionellosis ³⁶	11.26	TLR5 TLR4 TLR2 IL6 IL18 CXCL8
48	Overview of nanoparticle effects ¹	11.1	IL6 CXCL8 CRP
49	G-protein signaling_Rap2B regulation pathway ²³	11.06	IL6 IL18 CXCL8 CXCL1 CD40LG CCL2
50	Malaria ³⁶	10.87	TLR4 TLR2 IL6 IL18 CXCL8 CD40LG

Sources

GO Terms for Bacteriuria

Cellular components related to Bacteriuria according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular space	GO:0005615	9.81	UMOD IL6 IL18 CXCL8 CXCL1 CRP
2	cell surface	GO:0009986	9.73	UMOD TLR4 TLR2 CXCR2 CD40LG ARSB
3	external side of plasma membrane	GO:0009897	9.72	TLR4 CXCR2 CXCR1 CD79A CD40LG
4	extracellular region	GO:0005576	9.36	UMOD PRF1 IL6 IL18 CXCL8 CXCL1
5	Toll-like receptor 1-Toll-like receptor 2 protein complex	GO:0035354	8.96	TLR2 TLR1

Biological processes related to Bacteriuria according to GeneCards Suite gene sharing:

(show top 50) (show all 53)

#	Name	GO ID	Score	Top Affiliating Genes
1	signal transduction	GO:0007165	10.18	TLR5 TLR4 TLR2 TLR1 TIRAP IL6
2	immune system process	GO:0002376	10.17	TLR5 TLR4 TLR2 TLR1 TIRAP CD79A
3	innate immune response	GO:0045087	10.15	TLR5 TLR4 TLR2 TLR1 TIRAP CRP
4	positive regulation of gene expression	GO:0010628	10.11	TLR4 TLR2 IL6 IL18 CXCL8 CRP
5	neutrophil degranulation	GO:0043312	10.1	TLR2 CXCR2 CXCR1 CXCL1 CAT ARSB
6	negative regulation of cell proliferation	GO:0008285	10.09	UMOD TLR2 IL6 CXCL8 CXCL1
7	cell surface receptor signaling pathway	GO:0007166	10.05	TIRAP CXCR2 CXCR1 CD79A CCL2
8	cytokine-mediated signaling pathway	GO:0019221	10.05	IL6 IL18 CXCL8 CXCL1 CCL2
9	response to lipopolysaccharide	GO:0032496	9.98	UMOD TLR4 TLR2 TIRAP
10	chemotaxis	GO:0006935	9.98	CXCR2 CXCR1 CXCL8 CXCL1 CCL2
11	defense response to Gram-positive bacterium	GO:0050830	9.92	TLR2 TIRAP IL6 CRP
12	cellular response to lipopolysaccharide	GO:0071222	9.91	TLR5 TLR4 IL6 CXCL8 CXCL1 CCL2
13	cell chemotaxis	GO:0060326	9.89	CXCR2 CXCR1 CCL2
14	positive regulation of interleukin-6 production	GO:0032755	9.89	TLR4 TLR2 TLR1 TIRAP IL6
15	defense response to Gram-negative bacterium	GO:0050829	9.88	UMOD TLR4 IL6
16	calcium-mediated signaling	GO:0019722	9.88	CXCR2 CXCR1 CXCL8
17	positive regulation of tumor necrosis factor production	GO:0032760	9.88	TLR4 TLR2 TLR1 TIRAP IL6
18	toll-like receptor signaling pathway	GO:0002224	9.87	TLR5 TLR4 TLR2 TLR1
19	positive regulation of NIK/NF-kappaB signaling	GO:1901224	9.86	TLR4 TLR2 IL18
20	cellular defense response	GO:0006968	9.85	UMOD PRF1 CXCR2
21	receptor internalization	GO:0031623	9.85	CXCR2 CXCR1 CXCL8
22	neutrophil chemotaxis	GO:0030593	9.85	CXCR2 CXCR1 CXCL8 CXCL1 CCL2
23	positive regulation of interleukin-12 production	GO:0032735	9.84	TLR4 TLR2 TIRAP CD40LG
24	positive regulation of chemokine production	GO:0032722	9.83	TLR4 TLR2 IL6
25	positive regulation of interleukin-10 production	GO:0032733	9.83	TLR4 TLR2 IL6 CD40LG
26	lipopolysaccharide-mediated signaling pathway	GO:0031663	9.81	TLR4 TLR2 IL18 CCL2
27	chemokine-mediated signaling pathway	GO:0070098	9.8	CXCR2 CXCR1 CXCL8 CXCL1 CCL2
28	positive regulation of NF-kappaB transcription factor activity	GO:0051092	9.8	TLR4 TLR2 TIRAP IL6 IL18 CD40LG
29	positive regulation of nitric-oxide synthase biosynthetic process	GO:0051770	9.77	TLR4 TLR2 CCL2
30	neutrophil activation	GO:0042119	9.77	IL18 CXCR2 CXCL8
31	cellular response to lipoteichoic acid	GO:0071223	9.75	TLR4 TLR2 TIRAP
32	cellular response to bacterial lipopeptide	GO:0071221	9.73	TLR2 TLR1 TIRAP
33	immune response	GO:0006955	9.73	TLR5 TLR4 TLR2 TLR1 IL6 IL18
34	regulation of cytokine secretion	GO:0050707	9.72	TLR5 TLR2 TLR1
35	MyD88-dependent toll-like receptor signaling pathway	GO:0002755	9.72	TLR5 TLR4 TLR2 TLR1 TIRAP
36	positive regulation of neuroinflammatory response	GO:0150078	9.71	IL6 IL18
37	I-kappaB phosphorylation	GO:0007252	9.71	TLR4 TLR2
38	cell activation	GO:0001775	9.71	TLR2 TLR1
39	response to molecule of bacterial origin	GO:0002237	9.7	TLR2 CXCL8
40	positive regulation of chemokine (C-X-C motif) ligand 2 production	GO:2000343	9.7	TLR4 TIRAP
41	T-helper 1 type immune response	GO:0042088	9.7	TLR4 IL18
42	negative regulation of lipid storage	GO:0010888	9.69	IL6 CRP
43	positive regulation of toll-like receptor 2 signaling pathway	GO:0034137	9.68	TLR1 TIRAP
44	toll-like receptor TLR1:TLR2 signaling pathway	GO:0038123	9.67	TLR2 TLR1
45	positive regulation of toll-like receptor signaling pathway	GO:0034123	9.66	TLR5 TLR2
46	positive regulation of matrix metallopeptidase secretion	GO:1904466	9.65	TLR4 TLR2
47	cellular response to triacyl bacterial lipopeptide	GO:0071727	9.64	TLR2 TLR1
48	response to bacterial lipoprotein	GO:0032493	9.64	TLR2 TLR1
49	positive regulation of interleukin-8 production	GO:0032757	9.63	TLR5 TLR4 TLR2 TLR1 TIRAP IL6
50	positive regulation of cellular response to macrophage colony-stimulating factor stimulus	GO:1903974	9.62	TLR4 TLR2

Molecular functions related to Bacteriuria according to GeneCards Suite gene sharing:

(show all 13)

#	Name	GO ID	Score	Top Affiliating Genes
1	identical protein binding	GO:0042802	10.08	TLR4 TLR2 TLR1 TIRAP PRF1 CRP
2	signaling receptor activity	GO:0038023	9.81	TLR5 TLR4 TLR2 TLR1
3	transmembrane signaling receptor activity	GO:0004888	9.72	TLR5 TLR4 TLR2 TLR1 CD79A
4	chemokine activity	GO:0008009	9.63	CXCL8 CXCL1 CCL2
5	lipopeptide binding	GO:0071723	9.52	TLR2 TLR1
6	C-X-C chemokine receptor activity	GO:0016494	9.49	CXCR2 CXCR1
7	lipopolysaccharide receptor activity	GO:0001875	9.43	TLR4 TLR2
8	Toll-like receptor 2 binding	GO:0035663	9.4	TLR1 TIRAP
9	interleukin-8 binding	GO:0019959	9.37	CXCR2 CXCR1
10	NAD+ nucleotidase, cyclic ADP-ribose generating	GO:0061809	9.33	TLR4 TLR2 TLR1
11	interleukin-8 receptor activity	GO:0004918	9.26	CXCR2 CXCR1
12	NAD(P)+ nucleosidase activity	GO:0050135	9.13	TLR4 TLR2 TLR1
13	cytokine activity	GO:0005125	9.1	IL6 IL18 CXCL8 CXCL1 CD40LG CCL2

Sources

Sources for Bacteriuria

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GARD

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MedlinePlus Genetics

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 05-Apr-2021)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ Tocris

⁷⁰ UMLS

⁷¹ UMLS via Orphanet

⁷² UniProtKB/Swiss-Prot

⁷³ Wikipedia

Bacteriuria

Aliases & Classifications for Bacteriuria

MalaCards integrated aliases for Bacteriuria:

Classifications:

External Ids:

Summaries for Bacteriuria

Related Diseases for Bacteriuria

Diseases related to Bacteriuria via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Bacteriuria:

Symptoms & Phenotypes for Bacteriuria

MGI Mouse Phenotypes related to Bacteriuria:

Drugs & Therapeutics for Bacteriuria

Drugs for Bacteriuria (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

Interventional clinical trials:

Inferred drug relations via UMLS 70 / NDF-RT 51 :

Cochrane evidence based reviews: bacteriuria

Genetic Tests for Bacteriuria

Anatomical Context for Bacteriuria

MalaCards organs/tissues related to Bacteriuria:

Publications for Bacteriuria

Articles related to Bacteriuria:

Genes for Bacteriuria

Genes related to Bacteriuria (0 elite genes):

Variations for Bacteriuria

Expression for Bacteriuria

Pathways for Bacteriuria

Pathways related to Bacteriuria according to GeneCards Suite gene sharing:

GO Terms for Bacteriuria

Cellular components related to Bacteriuria according to GeneCards Suite gene sharing:

Biological processes related to Bacteriuria according to GeneCards Suite gene sharing:

Molecular functions related to Bacteriuria according to GeneCards Suite gene sharing:

Sources for Bacteriuria

Inferred drug relations via UMLS ⁷⁰ / NDF-RT ⁵¹ :