MCID: BGS001
MIFTS: 37

Bagassosis

Categories: Respiratory diseases

Aliases & Classifications for Bagassosis

MalaCards integrated aliases for Bagassosis:

Name: Bagassosis 12 15 71 32
Sugar Cane Worker Pneumonitis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:12522
ICD9CM 34 495.1
MeSH 43 D011009
NCIt 49 C34409
SNOMED-CT 67 67242002
ICD10 32 J67.1
UMLS 71 C0004681

Summaries for Bagassosis

Disease Ontology : 12 An extrinsic allergic alveolitis that is an industrial disease characterized by cough, difficult breathing, chills, fever, and prolonged weakness caused by the inhalation of the dust of bagasse containing thermophilic actinomycetes.

MalaCards based summary : Bagassosis, also known as sugar cane worker pneumonitis, is related to extrinsic allergic alveolitis and silicosis. An important gene associated with Bagassosis is IL1B (Interleukin 1 Beta), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Allograft rejection. Affiliated tissues include lung, liver and bone, and related phenotypes are Reduced mammosphere formation and neoplasm

Wikipedia : 74 Bagassosis, an interstitial lung disease, is a type of hypersensitivity pneumonitis attributed to... more...

Related Diseases for Bagassosis

Diseases related to Bagassosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 331)
# Related Disease Score Top Affiliating Genes
1 extrinsic allergic alveolitis 31.4 IL6 IL1B CXCL8
2 silicosis 30.6 TNF IL1B CXCL8
3 pneumoconiosis 29.9 TNF IL6 IL1B CXCL8
4 lung disease 29.4 TNF PRTN3 IL6 IL5 IL1B CXCL8
5 angelucci's syndrome 10.6 IL1B CXCL8
6 dermatitis, atopic, 8 10.6 IL1B CXCL8
7 esophagus melanoma 10.5 IL1B CXCL8
8 wells syndrome 10.4 IL5 IL1B CXCL8
9 granulomatous angiitis 10.3 PRTN3 IL5
10 prosthetic joint infection 10.3 IL6 IL1B
11 periodontitis, chronic 10.3 IL6 IL1B
12 acute transverse myelitis 10.3 IL6 CXCL8
13 allergic hypersensitivity disease 10.3
14 systemic onset juvenile idiopathic arthritis 10.3 TNF IL1B
15 uremic pruritus 10.3 IL6 IL1B
16 staphylococcal toxic shock syndrome 10.3 TNF IL1B
17 recurrent corneal erosion 10.3 IL6 IL1B CXCL8
18 peptic esophagitis 10.2 IL6 IL1B CXCL8
19 funisitis 10.2 IL6 IL1B CXCL8
20 conjunctivochalasis 10.2 IL6 IL1B CXCL8
21 vulvar vestibulitis syndrome 10.2 TNF IL1B
22 pyuria 10.2 PRTN3 IL6 CXCL8
23 palladium allergic contact dermatitis 10.2 TNF IL1B
24 kashin-beck disease 10.2 TNF IL1B
25 fuchs' heterochromic uveitis 10.2 IL6 CXCL8
26 inclusion body myopathy with paget disease of bone and frontotemporal dementia 10.2 HNRNPDL HNRNPC HNRNPA2B1
27 newborn respiratory distress syndrome 10.2 IL6 IL1B CXCL8
28 opisthorchiasis 10.2 TNF IL1B CXCL8
29 posterior scleritis 10.1 TNF PRTN3
30 crohn's colitis 10.1 TNF IL1B CXCL8
31 autoimmune vasculitis 10.1 TNF PRTN3 IL1B
32 lung cancer 10.1
33 byssinosis 10.1
34 anthracosis 10.1
35 aluminosis 10.1
36 cytokine deficiency 10.1
37 cyclic neutropenia 10.1 TNF IL1B CXCL8
38 haemophilus influenzae 10.1 TNF CXCL8
39 cryptogenic organizing pneumonia 10.1 TNF PRTN3 CXCL8
40 aseptic meningitis 10.1 TNF IL1B CXCL8
41 toxicodendron dermatitis 10.1 TNF CXCL8
42 yellow fever 10.1 IL6 IL5 IL1B
43 endometrial stromal tumor 10.1 MT-CO1 HNRNPDL HNRNPC
44 frontotemporal dementia and/or amyotrophic lateral sclerosis 1 10.1 HNRNPDL HNRNPC HNRNPA2B1
45 optic neuritis 10.1 TNF IL1B CXCL8
46 dermatitis herpetiformis 10.1 TNF IL5 CXCL8
47 ascaris lumbricoides infection 10.1 IL6 IL5 IL1B CXCL8
48 scleritis 10.1 TNF PRTN3 IL5
49 castleman disease 10.1 IL6 IL5 CXCL8
50 allergic conjunctivitis 10.1 TNF IL5 CXCL8

Graphical network of the top 20 diseases related to Bagassosis:



Diseases related to Bagassosis

Symptoms & Phenotypes for Bagassosis

GenomeRNAi Phenotypes related to Bagassosis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.17 CXCL8 HARS2 HNRNPC IL5 PRTN3 RAD51

MGI Mouse Phenotypes related to Bagassosis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 9.17 HM13 HSPA5 IL1B IL5 IL6 SHC1

Drugs & Therapeutics for Bagassosis

Search Clinical Trials , NIH Clinical Center for Bagassosis

Genetic Tests for Bagassosis

Anatomical Context for Bagassosis

MalaCards organs/tissues related to Bagassosis:

40
Lung, Liver, Bone, Thyroid, Monocytes, Skin, Eye

Publications for Bagassosis

Articles related to Bagassosis:

(show top 50) (show all 67)
# Title Authors PMID Year
1
Complete genome sequence of Saccharomonospora viridis type strain (P101). 61
21304650 2009
2
Respiratory health effects and immunological response to Thermoactinomyces among sugar cane workers in Nicaragua. 61
19650579 2009
3
Differences in cellular and inflammatory cytokine profiles in the bronchoalveolar lavage fluid in bagassosis and silicosis. 61
15376226 2004
4
Hypersensitivity pneumonitis: a comprehensive review. 61
11436968 2001
5
The medical and epidemiologic effects on workers of the levels of airborne Thermoactinomyces Spp. spores present in Australian raw sugar mills. 61
8931309 1996
6
Occupational hypersensitivity pneumonitis in Japan: data on a nationwide epidemiological study. 61
7550795 1995
7
Hypersensitivity pneumonitis: bagassosis. 61
7807612 1994
8
Recent trends in bagassosis in Japan. 61
1637710 1992
9
Aspects of occupational health in the sugar cane industry. 61
1921344 1991
10
[Diagnostic aspects of allergic alveolitis]. 61
2099011 1990
11
Clinical, epidemiological, and laboratory criteria for the diagnosis of bagassosis. 61
2305800 1990
12
[Experimental and clinical studies on the pathogenicity of extracellular proteinases of Streptomyces thermohygroscopicus in farmer's lung]. 61
2698769 1989
13
[A report on 2 cases of bagassosis and a review of relevant literature]. 61
2805146 1989
14
Enzyme-linked immunosorbent-assay (ELISA) for IgG in bagasse workers' sera: comparison with counter-immunoelectrophoresis. 61
3621552 1987
15
[Bagassosis. Report of a case]. 61
3915394 1985
16
Experimental bagassosis: role of infection. 61
6884291 1983
17
[Bagassosis in a sugar refinery (report of 10 cases)]. 61
7151586 1982
18
Pathophysiological disturbances in bagassosis and bagasse workers. 61
7116010 1982
19
[Bagassosis. Allergic pneumonitis in an industrial employer (author's transl)]. 61
7401736 1980
20
[Bagassosis, an occupational disease of the lungs (a review of the foreign literature)]. 61
374189 1979
21
Elimination of bagassosis in Louisiana paper manufacturing plant workers. 61
627039 1978
22
Bagassosis: a report of 8 cases. 61
4424270 1974
23
Bagassosis: a histopathologic study of pulmonary biopsies from six cases. 61
4712724 1973
24
[Bagassosis in Spain]. 61
5071213 1972
25
[Bagassosis and other plant dust pneumoconioses]. 61
4942470 1971
26
Sequential observations on pulmonary functional derangements in Bagassosis. 61
5111660 1971
27
Thermoactinomyces sacchari sp. nov., a thermophilic actinomycete causing bagassosis. 61
4999215 1971
28
Pulmonary function at rest and during exercise following bagassosis. 61
4995433 1971
29
Prevention of bagassosis by addition of propionic acid to sugar cane waste. 61
5201841 1970
30
Bagassosis. (A case report). 61
5456139 1970
31
[Bagassosis]. 61
5513447 1970
32
Bagassosis. IV. Precipitins against extracts of thermophilic actinomycetes in patients with bagassosis. 61
4182997 1969
33
[Studies on bagassosis]. 61
5801844 1969
34
Immunological aspects of bagassosis. 61
4972748 1968
35
Bagassosis: an epidemiological, environmental, and clinical survey. 61
5723350 1968
36
Pulmonary function in bagassosis. 61
5673109 1968
37
Bagassosis. 61
4170904 1968
38
Bagassosis. 61
5609030 1967
39
Bagassosis II. Skin reactivity to crude bagasse extracts and atopic status of patients. 61
4960059 1967
40
Bagassosis: I. Precipitins against extracts of crude bagasse in the serum of patients. 61
23841195 1966
41
Bagassosis: a study of pulmonary function in 20 cases. 61
23841194 1966
42
THE RESURGENCE OF BAGASSOSIS IN LOUISIANA. 61
14218625 1964
43
[BAGASSOSIS (COMMUNICATION OF THE 1ST CASE REGISTERED IN SPAIN)]. 61
14208062 1964
44
Bagassosis. 61
13997509 1963
45
In vitro studies on the utilization of glucose-1-14C by guinea-pig lungs in experimental bagassosis. 61
13977669 1962
46
Metastasizing lung cancer associated with past bagassosis. 61
13940182 1962
47
Bagassosis and silicosis in the Philippines. 61
14028138 1962
48
Bagassosis: a true pnemoconiosis. 61
13874417 1962
49
Glycogen metabolism of guinea-pig in experimental bagassosis. 61
13913344 1962
50
Cellular constituents of guinea-pig lungs in experimental bagassosis. 61
13913343 1962

Variations for Bagassosis

Expression for Bagassosis

Search GEO for disease gene expression data for Bagassosis.

Pathways for Bagassosis

Pathways related to Bagassosis according to GeneCards Suite gene sharing:

(show all 43)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.34 TNF SHC1 PRTN3 IL6 IL5 IL1B
2
Show member pathways
12.65 TNF IL6 IL5 IL1B HSPA5 HARS1
3
Show member pathways
12.58 TNF SHC1 IL6 IL5 IL1B
4
Show member pathways
12.56 TNF SHC1 RAD51 IL6 IL1B
5 12.28 TNF IL6 IL1B CXCL8
6
Show member pathways
12.28 TNF SHC1 IL6 IL1B CXCL8
7
Show member pathways
12.26 TNF IL6 IL5 IL1B CXCL8
8
Show member pathways
12.25 TNF IL6 IL5 IL1B CXCL8
9 12.22 TNF IL6 IL1B CXCL8
10 12.22 TNF LAMP2 IL6 IL1B
11
Show member pathways
12.18 TNF IL6 IL1B CXCL8
12 12.16 TNF IL6 IL1B CXCL8
13
Show member pathways
12.1 TNF SHC1 IL6 IL1B CXCL8
14 11.99 TNF IL6 IL1B CXCL8
15 11.99 TNF IL6 IL1B CXCL8
16 11.95 TNF IL6 IL1B CXCL8
17 11.9 LAMP2 IL6 IL1B CXCL8
18 11.88 TNF IL6 IL1B CXCL8
19 11.86 TNF IL6 IL1B CXCL8
20 11.84 TNF IL6 IL5 IL1B
21 11.81 TNF IL6 IL1B CXCL8
22 11.78 IL6 IL5 CXCL8
23 11.76 IL6 IL1B CXCL8
24 11.76 TNF IL5 IL1B
25
Show member pathways
11.73 TNF IL5 CXCL8
26 11.7 TNF IL6 IL1B
27 11.68 TNF IL6 IL1B CXCL8
28 11.65 TNF LAMP2 IL6 IL1B
29
Show member pathways
11.53 TNF IL6 IL1B CXCL8
30 11.51 IL6 IL5 IL1B
31 11.48 TNF IL6 IL1B
32 11.46 TNF IL6 IL1B CXCL8
33 11.37 TNF IL6 IL1B
34 11.34 IL6 IL1B HSPA5
35 11.34 TNF IL6 IL1B
36 11.32 TNF IL6 IL1B CXCL8
37 11.27 TNF IL6 IL1B
38 11.25 TNF IL6 IL1B CXCL8
39
Show member pathways
11.19 SHC1 HNRNPC HNRNPA2B1
40 10.97 TNF IL6 CXCL8
41 10.96 TNF IL6 IL5 IL1B
42 10.82 TNF IL6 IL5 IL1B CXCL8
43 10.72 TNF IL6 IL5 IL1B

GO Terms for Bagassosis

Cellular components related to Bagassosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.56 TNF PRTN3 LAMP2 IL6 IL5 IL1B
2 extracellular region GO:0005576 9.32 TNF PRTN3 IL6 IL5 IL1B HNRNPC

Biological processes related to Bagassosis according to GeneCards Suite gene sharing:

(show all 22)
# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.98 TNF IL6 IL5 IL1B CXCL8
2 inflammatory response GO:0006954 9.91 TNF IL6 IL5 IL1B CXCL8
3 MAPK cascade GO:0000165 9.89 TNF SHC1 IL5 IL1B
4 cellular response to lipopolysaccharide GO:0071222 9.83 TNF IL6 IL1B CXCL8
5 positive regulation of interleukin-6 production GO:0032755 9.73 TNF IL6 IL1B
6 humoral immune response GO:0006959 9.71 TNF IL6 GPI
7 positive regulation of DNA-binding transcription factor activity GO:0051091 9.71 TNF IL6 IL5 IL1B
8 positive regulation of podosome assembly GO:0071803 9.61 TNF IL5
9 positive regulation of JAK-STAT cascade GO:0046427 9.61 TNF IL6 IL5
10 PERK-mediated unfolded protein response GO:0036499 9.6 HSPA5 CXCL8
11 positive regulation of chemokine biosynthetic process GO:0045080 9.58 TNF IL1B
12 negative regulation of lipid storage GO:0010888 9.57 TNF IL6
13 regulation of establishment of endothelial barrier GO:1903140 9.55 TNF IL1B
14 negative regulation of neurogenesis GO:0050768 9.54 TNF IL6 IL1B
15 positive regulation of fever generation GO:0031622 9.49 TNF IL1B
16 sequestering of triglyceride GO:0030730 9.48 TNF IL1B
17 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.46 TNF IL1B
18 positive regulation of glial cell proliferation GO:0060252 9.43 TNF IL6 IL1B
19 positive regulation of neuroinflammatory response GO:0150078 9.33 TNF IL6 IL1B
20 histidyl-tRNA aminoacylation GO:0006427 9.32 HARS2 HARS1
21 cytokine-mediated signaling pathway GO:0019221 9.17 TNF SHC1 PRTN3 IL6 IL5 IL1B
22 positive regulation of immunoglobulin secretion GO:0051024 9.13 IL6 IL5 GPI

Molecular functions related to Bagassosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 10.11 TNF SHC1 RAD51 PRTN3 MYOM2 MT-CO1
2 N6-methyladenosine-containing RNA binding GO:1990247 9.26 HNRNPC HNRNPA2B1
3 cytokine activity GO:0005125 9.1 TNF IL6 IL5 IL1B GPI CXCL8
4 histidine-tRNA ligase activity GO:0004821 8.96 HARS2 HARS1

Sources for Bagassosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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