MCID: BLN010
MIFTS: 35

Balanitis

Categories: Reproductive diseases

Aliases & Classifications for Balanitis

Summaries for Balanitis

MalaCards based summary : Balanitis is related to balanitis xerotica obliterans and leukoplakia of penis. An important gene associated with Balanitis is TGM2 (Transglutaminase 2). The drugs Ketorolac and Bupivacaine have been mentioned in the context of this disorder. Affiliated tissues include skin, bone and bone marrow, and related phenotype is behavior/neurological.

Wikipedia : 77 Balanitis is inflammation of the glans penis. When the foreskin is also affected, it is termed... more...

Related Diseases for Balanitis

Graphical network of the top 20 diseases related to Balanitis:



Diseases related to Balanitis

Symptoms & Phenotypes for Balanitis

MGI Mouse Phenotypes related to Balanitis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.02 PHB2 SLC5A2 TGM1 TGM2 TGM3

Drugs & Therapeutics for Balanitis

Drugs for Balanitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 35)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ketorolac Approved Phase 1 66635-83-4, 74103-06-3 3826
2
Bupivacaine Approved, Investigational Phase 1 2180-92-9, 38396-39-3 2474
3
Acetaminophen Approved Phase 1 103-90-2 1983
4
Sevoflurane Approved, Vet_approved Phase 1 28523-86-6 5206
5
Ibuprofen Approved Phase 1 15687-27-1 3672
6 Ketorolac Tromethamine Phase 1
7 Central Nervous System Depressants Phase 1
8 Peripheral Nervous System Agents Phase 1
9 Anti-Inflammatory Agents Phase 1,Not Applicable
10 Cyclooxygenase Inhibitors Phase 1
11 Anti-Inflammatory Agents, Non-Steroidal Phase 1
12 Antipyretics Phase 1
13 Anesthetics Phase 1
14 Anesthetics, Inhalation Phase 1
15 Anesthetics, Local Phase 1
16 Analgesics Phase 1
17 Platelet Aggregation Inhibitors Phase 1
18 Anesthetics, General Phase 1
19 Antirheumatic Agents Phase 1
20 Analgesics, Non-Narcotic Phase 1
21 Anti-Infective Agents Phase 1
22
Adenosine Approved, Investigational 58-61-7 60961
23
Triamcinolone Approved, Vet_approved Not Applicable 124-94-7 31307
24
Vitamin A Approved, Nutraceutical, Vet_approved Not Applicable 22737-96-8, 68-26-8, 11103-57-4 9904001 445354
25 retinol Not Applicable
26 Hormones Not Applicable
27 Immunosuppressive Agents Not Applicable
28 Retinol palmitate Not Applicable
29 Triamcinolone hexacetonide Not Applicable
30 glucocorticoids Not Applicable
31 Hormones, Hormone Substitutes, and Hormone Antagonists Not Applicable
32 triamcinolone acetonide Not Applicable
33 Hormone Antagonists Not Applicable
34 Immunologic Factors Not Applicable
35 Triamcinolone diacetate Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Evaluating Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision Completed NCT02973958 Phase 1 Bupivacaine;Sevoflurane;Acetaminophen;Ibuprofen;Ketorolac
2 Safety and Acceptability of Carraguard™ Among HIV-negative Couples in Thailand Completed NCT00213057 Phase 1 Carraguard (PC-515)
3 Susceptibility Genes in Autism Spectrum Disorders Unknown status NCT02628808
4 Circumcision Versus Preputioplasty for BXO in Children Completed NCT02854995 Not Applicable

Search NIH Clinical Center for Balanitis

Cochrane evidence based reviews: balanitis

Genetic Tests for Balanitis

Anatomical Context for Balanitis

MalaCards organs/tissues related to Balanitis:

42
Skin, Bone, Bone Marrow, T Cells

Publications for Balanitis

Articles related to Balanitis:

(show top 50) (show all 328)
# Title Authors Year
1
Topical mupirocin 2% ointment for diagnosis of Zoon's balanitis and monotherapy of balanitis circumscripta plasmacellularis. ( 30604433 )
2019
2
Surgical managements of pseudoepitheliomatous keratotic and micaceous balanitis: A case report. ( 30684817 )
2019
3
Re: Single-Stage Urethroplasty with Buccal Mucosal Inlay Graft for Stricture Caused by Balanitis Xerotica Obliterans in Boys: . ( 30759653 )
2019
4
Pseudo circinate balanitis: great masquerader lives. ( 30808720 )
2019
5
A case-control study of risk factors associated with Zoon balanitis in men. ( 30903714 )
2019
6
Candida Balanitis with Hyperplastic Plaque Mimicking Vascular Neoplasm. ( 29722348 )
2018
7
Syphilitic balanitis of Follmann. ( 29564878 )
2018
8
Handheld reflectance confocal microscopy, dermatoscopy and histopathological correlation of common inflammatory balanitis. ( 29457262 )
2018
9
Does application of topical steroids for lichen sclerosus (balanitis xerotica obliterans) affect the rate of circumcision? A systematic review. ( 29395150 )
2018
10
Balanitis associated with FOLFIRI chemotherapy. ( 29387750 )
2018
11
Anti-Inflammatory and Tissue Regenerative Effects of Topical Treatment with Ozonated Olive Oil/Vitamin E Acetate in Balanitis Xerotica Obliterans. ( 29534008 )
2018
12
Utility of uroflowmetry during the follow-up of children affected by balanitis xerotica obliterans (BXO). ( 29974722 )
2018
13
Balanitis, Circumscripta Plasmacellularis (Plasma Cell Balanitis, Zoon Balanitis) ( 29489180 )
2018
14
Balanitis circinata. ( 30071931 )
2018
15
Zoon's plasma cell balanitis: clinical and dermoscopic features in pediatric patients. ( 30117600 )
2018
16
Balanitis in Acute Lymphoblastic Leukemia: A Rare Etiology and Unusual Presentation. ( 30127570 )
2018
17
10 Years' Experience in Balanitis Xerotica Obliterans: A Single-Institution Study. ( 30130825 )
2018
18
Circumcision is still the gold standard in management of plasma cell balanitis. ( 30246920 )
2018
19
Balanitis xerotica obliterans: a review of diagnosis and management. ( 30315576 )
2018
20
Accuracy of dermoscopy in distinguishing erythroplasia of Queyrat from common forms of chronic balanitis: results from a multicentric observational study. ( 30468529 )
2018
21
Syphilitic balanitis of Follmann: two case reports. ( 30471083 )
2018
22
Thalidomide in plasma cell balanitis refractory to conventional topical treatment. ( 30484535 )
2018
23
Image Gallery: Generalized circinate cutaneous lesions simulating circinate balanitis. ( 29192976 )
2017
24
Role of urethral plate and fossa navicularis biopsies in the detection of balanitis xerotica obliterans in boys undergoing redo hypospadias repair. ( 29234536 )
2017
25
Circinate Balanitis. ( 28076706 )
2017
26
Pseudoepitheliomatous keratotic and micaceous balanitis treated with topical 5-fluorouracil and liquid nitrogen. ( 28406530 )
2017
27
Single-stage urethroplasty with buccal mucosal inlay graft for stricture caused by balanitis xerotica obliterans in boys: Outcomes in the medium term. ( 29150196 )
2017
28
Zoon's balanitis treated with topical tacrolimus. ( 28479782 )
2017
29
Balanitis: A Unique Presentation of Diabetes in an Elderly Male. ( 29467066 )
2017
30
Squamous Cell Carcinoma Penis in a Case of Urethral Stricture Due to Lichen Sclerosus Balanitis Xerotica Obliterans: A Case Report and Review of Literature. ( 28892974 )
2017
31
Zoon Balanitis Revisited: Report of Balanitis Circumscripta Plasmacellularis Resolving With Topical Mupirocin Ointment Monotherapy. ( 28301626 )
2017
32
A case of Zoon Balanitis in an immune-competent teenager. ( 28895662 )
2017
33
Balanitis xerotica obliterans: has its diagnostic accuracy improved with time? ( 28620502 )
2017
34
Successful Management of Zoon's Balanitis with Topical Mupirocin Ointment: A Case Report and Literature Review of Mupirocin-Responsive Balanitis Circumscripta Plasmacelluaris. ( 28382428 )
2017
35
Erratum to: Successful Management of Zoon's Balanitis with Topical Mupirocin Ointment: A Case Report and Literature Review of Mupirocin-Responsive Balanitis Circumscripta Plasmacellularis. ( 28425049 )
2017
36
Streptococcus pyogenes as the cause of vulvovaginitis and balanitis in children from Nis, Serbia. ( 27638252 )
2016
37
Expression of Transglutaminase in Foreskin of Children with Balanitis Xerotica Obliterans. ( 27649154 )
2016
38
Zoon balanitis: A comprehensive review. ( 27890945 )
2016
39
The clinical spectrum of syphilitic balanitis of Follmann: report of five cases and a review of the literature. ( 27421838 )
2016
40
Contact balanitis to tromantadine. ( 27757977 )
2016
41
Response to commentary to 'Bleeding after circumcision is more likely in children with Lichen Sclerosus (Balanitis Xerotica Obliterans)'. ( 28089293 )
2016
42
Recurrence after management of meatal balanitis xerotica obliterans. ( 28089110 )
2016
43
Bleeding after circumcision is more likely in children with lichen sclerosus (balanitis xerotica obliterans). ( 28043767 )
2016
44
Reflectance confocal microscopy as a non-invasive complementary tool in the diagnosis of psoriatic balanitis. ( 27514619 )
2016
45
Pseudoepitheliomatous, Keratotic and Micaceous Balanitis: A Case Report. ( 26557598 )
2015
46
ZOON's BALANITIS SUCCESSFULLY TREATED WITH PHOTODYNAMIC THERAPY: CASE REPORT AND LITERATURE REVIEW. ( 26321748 )
2015
47
Reiter's disease: Circinate balanitis as alone preceding presentation - Successfully treated with pimecrolimus 1% cream. ( 26392659 )
2015
48
Balanitis is a risk factor for herpes zoster. ( 25596845 )
2015
49
Circinate balanitis as the presenting symptom of sexually-acquired reactive arthritis: a case report. ( 25918330 )
2015
50
Dermoscopy of Zoon's plasma cell balanitis. ( 26670716 )
2015

Variations for Balanitis

Expression for Balanitis

Search GEO for disease gene expression data for Balanitis.

Pathways for Balanitis

GO Terms for Balanitis

Cellular components related to Balanitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 8.92 SLC5A2 TGM1 TGM2 TGM3

Biological processes related to Balanitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.32 TGM1 TGM3
2 cellular protein modification process GO:0006464 9.26 TGM1 TGM3
3 keratinocyte differentiation GO:0030216 9.16 TGM1 TGM3
4 cell envelope organization GO:0043163 8.96 TGM1 TGM3
5 peptide cross-linking GO:0018149 8.8 TGM1 TGM2 TGM3

Molecular functions related to Balanitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transferase activity, transferring acyl groups GO:0016746 9.13 TGM1 TGM2 TGM3
2 protein-glutamine gamma-glutamyltransferase activity GO:0003810 8.8 TGM1 TGM2 TGM3

Sources for Balanitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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