MCID: BLN002
MIFTS: 38

Balanitis Xerotica Obliterans

Categories: Reproductive diseases

Aliases & Classifications for Balanitis Xerotica Obliterans

MalaCards integrated aliases for Balanitis Xerotica Obliterans:

Name: Balanitis Xerotica Obliterans 12 44 15 72
Penile Lichen Sclerosus 12
Penile Leukoplakia 72

Classifications:



External Ids:

Disease Ontology 12 DOID:13477
ICD9CM 35 607.81
MeSH 44 D052798
NCIt 50 C3523
SNOMED-CT 68 43790000
UMLS 72 C0022782 C0152460

Summaries for Balanitis Xerotica Obliterans

Disease Ontology : 12 A balantitis characterized by white plaques or patches on genitals.

MalaCards based summary : Balanitis Xerotica Obliterans, also known as penile lichen sclerosus, is related to lichen sclerosus and balanitis. An important gene associated with Balanitis Xerotica Obliterans is TGM2 (Transglutaminase 2), and among its related pathways/superpathways are Pathways in cancer and Mitotic G1-G1/S phases. The drugs Triamcinolone and Vitamin A have been mentioned in the context of this disorder. Affiliated tissues include skin and t cells, and related phenotypes are behavior/neurological and cellular

Wikipedia : 75 Lichen sclerosus (LS) is a skin disease of unknown cause, commonly appearing as whitish patches on the... more...

Related Diseases for Balanitis Xerotica Obliterans

Diseases related to Balanitis Xerotica Obliterans via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 114, show less)
# Related Disease Score Top Affiliating Genes
1 lichen sclerosus 33.6 TP53 ELN
2 balanitis 32.8 TGM3 TGM2 TGM1
3 penile disease 30.8 TP53 CDKN2A
4 verrucous carcinoma 30.5 TP53 CDKN2A
5 squamous cell carcinoma 30.4 VEGFA TP53 PTGS2 CDKN2A
6 leukoplakia of penis 12.2
7 lichen sclerosus et atrophicus 12.1
8 peyronie's disease 11.7
9 phimosis 11.0
10 urethral stricture 10.9
11 hypospadias 10.8
12 elastosis perforans serpiginosa 10.6 TGM1 ELN
13 penile cancer 10.6
14 impotence 10.6
15 malignant tumor of penis 10.6
16 in situ carcinoma 10.5
17 infiltrating angiolipoma 10.5 VEGFA CDKN2A
18 autoimmune disease of skin and connective tissue 10.5 TGM3 TGM2
19 bowenoid papulosis 10.4 PTGS2 CDKN2A
20 autoimmune disease 10.4
21 vitiligo-associated multiple autoimmune disease susceptibility 6 10.4
22 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.4
23 vitiligo-associated multiple autoimmune disease susceptibility 1 10.4
24 telangiectasis 10.4
25 balanoposthitis 10.4
26 cystitis 10.4
27 adenosquamous carcinoma 10.4
28 urinary tract obstruction 10.4
29 duplication of urethra 10.4
30 optic disk drusen 10.4 VEGFA ELN
31 radiation proctitis 10.3 VEGFA PECAM1
32 bladder squamous cell carcinoma 10.3 TP53 CDKN2A
33 keratinizing squamous cell carcinoma 10.3 TP53 CDKN2A
34 spitz nevus 10.3 TP53 CDKN2A
35 bladder carcinoma in situ 10.3 TP53 CDKN2A
36 scrotal carcinoma 10.3 TP53 CDKN2A
37 capillary hemangioma 10.3 VEGFA PECAM1
38 vulva squamous cell carcinoma 10.3 TP53 CDKN2A
39 bartholin's gland disease 10.3 TP53 CDKN2A
40 nasal cavity adenocarcinoma 10.3 TP53 CDKN2A
41 vulvar disease 10.3 TP53 CDKN2A
42 thyroid lymphoma 10.3 TP53 CDKN2A
43 anal squamous cell carcinoma 10.3 TP53 CDKN2A
44 gastric adenosquamous carcinoma 10.3 TP53 CDKN2A
45 glycogen-rich clear cell breast carcinoma 10.3 TP53 CDKN2A
46 hydrocele 10.3 VEGFA PECAM1
47 megaesophagus 10.3 TP53 CDKN2A
48 oral leukoplakia 10.3 TP53 CDKN2A
49 uterus carcinoma in situ 10.3 TP53 CDKN2A
50 cervix uteri carcinoma in situ 10.3 TP53 CDKN2A
51 anogenital venereal wart 10.3 TP53 CDKN2A
52 meningeal melanomatosis 10.2 TP53 CDKN2A
53 protoplasmic astrocytoma 10.2 TP53 PTGS2
54 recurrent respiratory papillomatosis 10.2 TP53 PTGS2
55 suppressor of tumorigenicity 3 10.2 TP53 CDKN2A
56 dedifferentiated liposarcoma 10.2 TP53 CDKN2A
57 soft tissue sarcoma 10.2 VEGFA TP53
58 endocervical adenocarcinoma 10.2 TP53 CDKN2A
59 cervical adenosquamous carcinoma 10.2 PTGS2 CDKN2A
60 gastric lymphoma 10.2 VEGFA TP53
61 retinoblastoma 10.1
62 scleroderma, familial progressive 10.1
63 graft-versus-host disease 10.1
64 skin disease 10.1
65 familial retinoblastoma 10.1
66 rapidly involuting congenital hemangioma 10.1
67 esophagus adenocarcinoma 10.1 TP53 PTGS2
68 cervix small cell carcinoma 10.1 TP53 CDKN2A
69 basaloid squamous cell carcinoma 10.1 TP53 CDKN2A
70 nasopharyngeal disease 10.0 VEGFA TP53 CDKN2A
71 pharynx cancer 10.0 VEGFA TP53 CDKN2A
72 cerebrum cancer 10.0 VEGFA TP53 CDKN2A
73 cervix disease 10.0 VEGFA TP53 CDKN2A
74 supratentorial cancer 10.0 VEGFA TP53 CDKN2A
75 grade iii astrocytoma 10.0 VEGFA TP53 CDKN2A
76 uterine anomalies 10.0 VEGFA TP53 CDKN2A
77 central nervous system cancer 10.0 VEGFA TP53 CDKN2A
78 nervous system cancer 10.0 VEGFA TP53 CDKN2A
79 necrotizing sialometaplasia 10.0 TP53 CDKN2A
80 laryngeal squamous cell carcinoma 10.0 VEGFA TP53 CDKN2A
81 female reproductive system disease 10.0 VEGFA TP53 CDKN2A
82 endometrial adenocarcinoma 10.0 VEGFA TP53 CDKN2A
83 respiratory system cancer 10.0 VEGFA TP53 CDKN2A
84 endocrine gland cancer 10.0 VEGFA TP53 CDKN2A
85 meningioma, familial 10.0 VEGFA TP53 CDKN2A
86 tongue disease 10.0 TP53 CDKN2A
87 barrett's adenocarcinoma 10.0 TP53 PTGS2 CDKN2A
88 actinic keratosis 10.0 TP53 PTGS2 CDKN2A
89 esophageal disease 10.0 TP53 PTGS2 CDKN2A
90 cervical adenocarcinoma 10.0 TP53 PTGS2 CDKN2A
91 gastrointestinal stromal tumor 9.9 VEGFA TP53 CDKN2A
92 oral cancer 9.9 TP53 PTGS2 CDKN2A
93 transitional cell carcinoma 9.9 TP53 PTGS2 CDKN2A
94 colonic disease 9.9 VEGFA TP53 PTGS2
95 colorectal adenocarcinoma 9.9 VEGFA TP53 PTGS2
96 stomach disease 9.9 VEGFA TP53 PTGS2
97 intestinal disease 9.9 VEGFA TP53 PTGS2
98 barrett esophagus 9.9 TP53 PTGS2 CDKN2A
99 gallbladder cancer 9.9 TP53 PTGS2 CDKN2A
100 pancreatic ductal carcinoma 9.8 VEGFA TP53 TGM2 CDKN2A
101 optic nerve neoplasm 9.6 TP53 CDKN2A
102 reproductive system disease 9.6 VEGFA TP53 PTGS2 CDKN2A
103 gastrointestinal system cancer 9.6 VEGFA TP53 PTGS2 CDKN2A
104 gastrointestinal system disease 9.6 VEGFA TP53 PTGS2 CDKN2A
105 adenocarcinoma 9.6 VEGFA TP53 PTGS2 CDKN2A
106 adamantinoma of long bones 9.6 VEGFA TP53 PTGS2 CDKN2A
107 squamous cell carcinoma, head and neck 9.6 VEGFA TP53 PTGS2 CDKN2A
108 large intestine cancer 9.6 VEGFA TP53 PTGS2 CDKN2A
109 gastric adenocarcinoma 9.6 VEGFA TP53 PTGS2 CDKN2A
110 myeloma, multiple 9.6 VEGFA TP53 CDKN2A
111 lung cancer susceptibility 3 9.6 VEGFA TP53 PTGS2 CDKN2A
112 cervical cancer 9.5 VEGFA TP53 PTGS2 CDKN2A
113 cholangiocarcinoma 9.4 TP53 PTGS2 CDKN2A
114 esophageal cancer 9.3 VEGFA TP53 TGM3 PTGS2 CDKN2A

Graphical network of the top 20 diseases related to Balanitis Xerotica Obliterans:



Diseases related to Balanitis Xerotica Obliterans

Symptoms & Phenotypes for Balanitis Xerotica Obliterans

MGI Mouse Phenotypes related to Balanitis Xerotica Obliterans:

46 (showing 13, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.13 AKTIP CDKN2A PTGS2 TGM1 TGM2 TGM3
2 cellular MP:0005384 10.11 CDKN2A LIN9 MCM3 PECAM1 PTGS2 TGM2
3 growth/size/body region MP:0005378 10.11 AKTIP CDKN2A LIN9 MCM3 PTGS2 TGM1
4 homeostasis/metabolism MP:0005376 10.09 CDKN2A MCM3 PECAM1 PTGS2 TGM1 TGM2
5 endocrine/exocrine gland MP:0005379 10.02 CDKN2A LIN9 MCM3 PTGS2 TGM2 TP53
6 digestive/alimentary MP:0005381 9.97 CDKN2A LIN9 PECAM1 PTGS2 TP53 VEGFA
7 integument MP:0010771 9.95 CDKN2A MCM3 PTGS2 TGM1 TGM3 TP53
8 liver/biliary system MP:0005370 9.85 CDKN2A MCM3 PECAM1 PTGS2 TP53 VEGFA
9 neoplasm MP:0002006 9.8 CDKN2A MCM3 PTGS2 TGM2 TP53 VEGFA
10 no phenotypic analysis MP:0003012 9.73 CDKN2A LIN9 PTGS2 TGM2 TP53 VEGFA
11 renal/urinary system MP:0005367 9.63 PECAM1 PTGS2 TGM2 TGM3 TP53 VEGFA
12 respiratory system MP:0005388 9.43 CDKN2A PECAM1 PTGS2 TGM3 TP53 VEGFA
13 skeleton MP:0005390 9.17 AKTIP CDKN2A PECAM1 PTGS2 TGM3 TP53

Drugs & Therapeutics for Balanitis Xerotica Obliterans

Drugs for Balanitis Xerotica Obliterans (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 14, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Triamcinolone Approved, Vet_approved 124-94-7 31307
2
Vitamin A Approved, Nutraceutical, Vet_approved 22737-96-8, 11103-57-4, 68-26-8 9904001 445354
3 Anti-Inflammatory Agents
4 triamcinolone acetonide
5 Triamcinolone hexacetonide
6 Triamcinolone diacetate
7 glucocorticoids
8 Hormones
9 Retinol palmitate
10 Immunosuppressive Agents
11 Hormone Antagonists
12 retinol
13 Immunologic Factors
14 Hormones, Hormone Substitutes, and Hormone Antagonists

Interventional clinical trials:

(showing 1, show less)
# Name Status NCT ID Phase Drugs
1 Circumcision Versus Preputioplasty for BXO in Children: A Feasibility Randomised Controlled Trial Completed NCT02854995

Search NIH Clinical Center for Balanitis Xerotica Obliterans

Cochrane evidence based reviews: balanitis xerotica obliterans

Genetic Tests for Balanitis Xerotica Obliterans

Anatomical Context for Balanitis Xerotica Obliterans

MalaCards organs/tissues related to Balanitis Xerotica Obliterans:

41
Skin, T Cells

Publications for Balanitis Xerotica Obliterans

Articles related to Balanitis Xerotica Obliterans:

(showing 225, show less)
# Title Authors PMID Year
1
Balanitis xerotica obliterans: a review of diagnosis and management. 38
30315576 2019
2
Pediatric lichen sclerosus: A systematic review of 4516 cases. 38
31260081 2019
3
10 Years' Experience in Balanitis Xerotica Obliterans: A Single-Institution Study. 38
30130825 2019
4
Re: Single-Stage Urethroplasty with Buccal Mucosal Inlay Graft for Stricture Caused by Balanitis Xerotica Obliterans in Boys: . 38
30759653 2019
5
Abnormal dartos fascia in buried penis and hypospadias: Evidence from histopathology. 38
30554609 2018
6
Does application of topical steroids for lichen sclerosus (balanitis xerotica obliterans) affect the rate of circumcision? A systematic review. 38
29395150 2018
7
Utility of uroflowmetry during the follow-up of children affected by balanitis xerotica obliterans (BXO). 38
29974722 2018
8
Penile Lichen Sclerosus Treated with 1927 nm Thulium Fiber Laser and Photodynamic Therapy: A New Possible Therapeutic Approach. 38
29298401 2018
9
Routine histopathological examination of the foreskin after circumcision for clinically suspected lichen sclerosus in children: Is it a waste of resources? 38
29405913 2018
10
Anti-Inflammatory and Tissue Regenerative Effects of Topical Treatment with Ozonated Olive Oil/Vitamin E Acetate in Balanitis Xerotica Obliterans. 38
29534008 2018
11
Single-stage urethroplasty with buccal mucosal inlay graft for stricture caused by balanitis xerotica obliterans in boys: Outcomes in the medium term. 38
29150196 2018
12
Surgical management of buried penis in adults. 38
30386659 2018
13
Treatment of penile lichen sclerosus with topical corticosteroids for over 25 years' duration: A case report. 38
30214805 2018
14
Can lichen sclerosus be diagnosed by preputial appearance or symptoms? 38
30271758 2018
15
Role of urethral plate and fossa navicularis biopsies in the detection of balanitis xerotica obliterans in boys undergoing redo hypospadias repair. 38
29234536 2017
16
Characteristics of Idiopathic Urethral Strictures: A Link to Remote Perineal Trauma? 38
28755966 2017
17
[Clinical and immunohistochemical correlation of balanitis xerotica obliterans]. 38
29266891 2017
18
Squamous Cell Carcinoma Penis in a Case of Urethral Stricture Due to Lichen Sclerosus Balanitis Xerotica Obliterans: A Case Report and Review of Literature. 38
28892974 2017
19
Balanitis xerotica obliterans: has its diagnostic accuracy improved with time? 38
28620502 2017
20
Recurrence after management of meatal balanitis xerotica obliterans. 38
28089110 2017
21
Bleeding after circumcision is more likely in children with lichen sclerosus (balanitis xerotica obliterans). 38
28043767 2017
22
Response to commentary to 'Bleeding after circumcision is more likely in children with Lichen Sclerosus (Balanitis Xerotica Obliterans)'. 38
28089293 2017
23
Autologous platelet-rich plasma (PRP) in chronic penile lichen sclerosus: the impact on tissue repair and patient quality of life. 38
28161837 2017
24
Two-stage hypospadias repair with a free graft for severe primary and revision hypospadias: A single surgeon's experience with long-term follow-up. 38
27746246 2017
25
The Association Between BXO and Obesity in Boys Undergoing Circumcision. 38
29204461 2017
26
Expression of Transglutaminase in Foreskin of Children with Balanitis Xerotica Obliterans. 38
27649154 2016
27
Penile Circular Fasciocutaneous (McAninch) Flap as an Option for Complex Anterior Urethral Stricture in Case of Non-Viable Buccal Mucosal Graft. 38
27630900 2016
28
Foreskin Morbidity in Uncircumcised Males. 38
27244821 2016
29
Management of Vesicoureteral Reflux by Endoscopic Injection of Dextranomer/Hyaluronic Acid in Adults. 38
27162514 2016
30
Benign penile skin anomalies in children: a primer for pediatricians. 38
25754752 2015
31
Penile lichen sclerosus: An urologist's nightmare! - A single center experience. 38
26229314 2015
32
Penile lichen sclerosus: An enigmatic and challenging disease. 38
26229315 2015
33
[Balanitis xerotica obliterans, underdiagnosed pathology of clinical relevance]. 38
27775307 2015
34
Steroid instillation for idiopathic urethritis in children: an 8-year experience. 38
24683102 2015
35
L1 gene sequence of a putative novel type human papillomavirus in an immunocompetent patient with glans lichen sclerosus. 38
25742152 2015
36
Meatal stenosis in boys following circumcision for lichen sclerosus (balanitis xerotica obliterans). 38
24992332 2014
37
[Current diagnosis and treatment of male genital lichen sclerosus]. 38
25095613 2014
38
Isolated preputial reconstruction in distal hypospadias. 38
24314817 2014
39
Treatment of urethral strictures in balanitis xerotica obliterans (BXO) using circular buccal mucosal meatoplasy: experience of 15 cases. 38
24704927 2014
40
SIU/ICUD Consultation on Urethral Strictures: Anterior urethra-lichen sclerosus. 38
24268357 2014
41
Balanitis xerotica obliterans in children and adolescents: a literature review and clinical series. 38
24295833 2014
42
Protein markers of malignant potential in penile and vulvar lichen sclerosus. 38
23399649 2013
43
[Balanitis xerotica obliterans with phimosis in elderly patients presenting with difficulty in urination]. 38
23827865 2013
44
Genital lichen sclerosus/balanitis xerotica obliterans in men with penile carcinoma: a critical analysis. 38
23356463 2013
45
Histopathological examination of the prepuce after circumcision: Is it a waste of resources? 38
23860069 2013
46
Intralesional adalimumab for the treatment of refractory balanitis xerotica obliterans. 38
23324752 2013
47
Incidence of balanitis xerotica obliterans in boys younger than 10 years presenting with phimosis. 38
23296396 2013
48
Therapeutic strategies for patients with micropenis or penile dysmorphic disorder. 38
22890302 2012
49
Balanitis xerotica obliterans in children and its incidence under the age of 5 years. 38
21705275 2012
50
Management of boys with abnormal appearance of meatus at circumcision for balanitis xerotica obliterans. 38
22613322 2012
51
Foreskin preputioplasty and intralesional triamcinolone: a valid alternative to circumcision for balanitis xerotica obliterans. 38
22498393 2012
52
Paediatric balanitis xerotica obliterans: an 8-year experience. 38
22649954 2012
53
Skin phototype and local trauma in the onset of balanitis xerotica obliterans (BXO) in circumcised patients. 38
22210729 2012
54
Penile lichen sclerosus (balanitis xerotica obliterans). 38
22085120 2011
55
Management of boys with abnormal appearance of meatus at circumcision for balanitis xerotica obliterans. 38
21929920 2011
56
Penile cancer: what's new? 38
21826001 2011
57
The Cleveland Clinic experience with adult hypospadias patients undergoing repair: their presentation and a new classification system. 38
21438977 2011
58
Critical outcome analysis of staged buccal mucosa graft urethroplasty for prior failed hypospadias repair in children. 38
21256520 2011
59
The surgical treatment of Balanitis Xerotica Obliterans. 38
21713168 2011
60
Lichen sclerosus in boys. 38
21307992 2011
61
Oral mucosa graft for repair of hypospadias: outcomes at puberty. 38
20961570 2010
62
The high rate of familial lichen sclerosus suggests a genetic contribution: an observational cohort study. 38
20202060 2010
63
Tubularized incised plate hypospadias repair for distal hypospadias. 38
19837000 2010
64
Penile cancer--prevention and premalignant conditions. 38
20691883 2010
65
Extensive balanitis xerotica obliterans of urethrocutaneous fistula presenting as mass in scrotum. 38
19913886 2010
66
Foreskin management: Survey of Canadian pediatric urologists. 38
20705867 2010
67
Case of a congenital urethral duplication being unmasked following circumcision for balanitis xerotica obliterans. 38
20529516 2010
68
Role of penile biopsy in the diagnosis of penile dermatoses. 38
20498111 2010
69
Implantation dermoid and balanitis xerotica obliterans: rare complications after hypospadias repair: case gallery and review of relevant literature. 38
19360553 2010
70
[Urethoplasty in balanitis xerotica obliterans. Technical variation]. 38
19721178 2009
71
Routine biopsies in pediatric circumcision: (non) sense? 38
19138882 2009
72
Conservative treatment of phimosis with fluticasone proprionate 0.05%: a clinical study in 1185 boys. 38
19097823 2009
73
Lingual mucosal graft urethroplasty for anterior urethral strictures. 38
18848349 2009
74
Malignant transformation of penile lichen sclerosus: exactly how common is it? 38
19126024 2008
75
Perineal urethrostomy stenosis repair with buccal mucosa: description of technique and report of four cases. 38
18789512 2008
76
Long standing balanitis xerotica obliterans resulting in renal impairment in a child. 38
18587589 2008
77
Penile lichen sclerosus after allogeneic stem cell transplantation. 38
18503592 2008
78
The role of two-stage repair in modern hypospadiology. 38
19468400 2008
79
Two-stage repair in hypospadias. 38
19468402 2008
80
Human papillomavirus-associated increase in p16INK4A expression in penile lichen sclerosus and squamous cell carcinoma. 38
18047520 2008
81
Urethral reconstruction in balanitis xerotica obliterans. 38
18931544 2008
82
[Dorsal meatoplasty for the treatment of meatal stenosis in patients with balanitis xerotica obliterans]. 38
18273971 2007
83
[Topical therapy of balanitis xerotica obliterans in childhood. Long-term clinical results and an overview]. 38
17994212 2007
84
[Lichen sclerosus in children with phimosis]. 38
17978785 2007
85
Lichen sclerosus: review of the literature and current recommendations for management. 38
17936829 2007
86
Long-term follow-up for reconstruction of strictures of the fossa navicularis with a single technique. 38
17627782 2007
87
Preputial skin free graft as dorsal onlay urethroplasty: Our experience of 73 patients. 38
19718289 2007
88
[Balanitis xerotica obliterans]. 38
21086381 2007
89
Paediatric preputial pathology: are we circumcising enough? 38
17316525 2007
90
Secondary hypospadias repair in two stages. 38
18947681 2006
91
Combined buccal mucosa graft and genital skin flap for reconstruction of extensive anterior urethral strictures. 38
17070336 2006
92
Is the association between balanitis xerotica obliterans and penile carcinoma underestimated? 38
16831147 2006
93
Association of penile lichen sclerosus and oncogenic human papillomavirus infection. 38
16796627 2006
94
Detailed analysis of the T-cell lymphocytic infiltrate in penile lichen sclerosus: an immunohistochemical and molecular investigation. 38
16681690 2006
95
The response of clinical balanitis xerotica obliterans to the application of topical steroid-based creams. 38
16516649 2006
96
Penile cancer. 38
16488287 2006
97
Penile carcinoma arising in balanitis xerotica obliterans. 38
16464280 2006
98
Penile lichen sclerosus: Correlation between histopathologic features and risk of cancer. 38
17311737 2006
99
Extensive balanitis xerotica obliterans (BXO) involving the anterior urethra and scrotum. 38
17180441 2006
100
[Urethroplasty with combined free tissue grafts]. 38
18843906 2006
101
Balanitis xerotica obliterans in boys. 38
16145451 2005
102
Lichen sclerosus. 38
16004624 2005
103
High incidence of balanitis xerotica obliterans in boys with phimosis: prospective 10-year study. 38
16060864 2005
104
Heroic measures may not always be justified in extensive urethral stricture due to lichen sclerosus (balanitis xerotica obliterans). 38
15879815 2005
105
The response of clinical balanitis xerotica obliterans to the application of topical steroid-based creams. 38
15852285 2005
106
Buccal mucosal urethroplasty for balanitis xerotica obliterans related urethral strictures: the outcome of 1 and 2-stage techniques. 38
15643208 2005
107
Heroic measures may not always be justified in extensive urethral stricture due to lichen sclerosus (balanitis xerotica obliterans). 38
15351594 2004
108
Significance of recent onset nocturnal enuresis in adult men: a prospective study. 38
15524224 2004
109
Home-dilatation of the urethral meatus in boys. 38
15008738 2004
110
Development of multifocal squamous cell carcinoma in lichen sclerosus et atrophicus of the penis associated to HCV hepatitis. 38
14871263 2004
111
Is preputioplasty effective and acceptable? 38
12949202 2003
112
Treatment of balanitis xerotica obliterans with topical tacrolimus. 38
12913735 2003
113
Troubles with the foreskin: one hundred consecutive referrals to paediatric surgeons. 38
12949201 2003
114
Microinvasive squamous cell carcinoma arising on lichen sclerosus of the penis. 38
12702081 2003
115
Circumcision for phimosis and other medical indications in Western Australian boys. 38
12580740 2003
116
Balanitis xerotica obliterans: epidemiologic distribution in an equal access health care system. 38
12602705 2003
117
Balanitis xerotica obliterans: a form of lichen sclerosus. 38
12602704 2003
118
Buccal mucosa grafts for hypospadias surgery: long-term results. 38
12352347 2002
119
Skin graft for 2-stage treatment of severe hypospadias: back to the future? 38
12352346 2002
120
Muscular, myocutaneous, and fasciocutaneous flaps in complex urethral reconstruction. 38
12371235 2002
121
Topical steroid therapy for phimosis. 38
12010594 2002
122
Incidence of penile lichen sclerosus. 38
11312451 2001
123
The response of balanitis xerotica obliterans to local steroid application compared with placebo in children. 38
11125410 2001
124
Urethral stone presenting as a stop valve--a rare complication of balanitis xerotica obliterans. 38
12092665 2001
125
Balanitis xerotica obliterans--a review. 38
11204255 2000
126
The treatment of balanitis xerotica obliterans. 38
10971272 2000
127
Lymphohistiocytic and granulomatous phlebitis in penile lichen sclerosus. 38
10949456 2000
128
Synchronous onset of penile lichen sclerosus and vitiligo. 38
10886180 2000
129
Diagnosis and clinical presentation of premalignant lesions of the penis. 38
11144899 2000
130
Balanitis xerotica obliterans with urethral stricture after hypospadias repair. 38
10663869 2000
131
Balanitis xerotica obliterans and its differential diagnosis. 38
10612365 1999
132
[Penile lichen sclerosus: follow-up study]. 38
10612857 1999
133
The incidence of phimosis in boys. 38
10444134 1999
134
Penile lichen sclerosus et atrophicus treated with clobetasol dipropionate 0.05% cream: a retrospective clinical and histopathological study. 38
10071317 1999
135
Balanitis xerotica obliterans complicating hypospadias repair. 38
10343594 1999
136
Long-term antibiotic therapy for balanitis xerotica obliterans. 38
9922014 1999
137
Urethroplasty for balanitis xerotica obliterans. 38
9634051 1998
138
Human papillomavirus is present in some cases of childhood penile lichen sclerosus: an in situ hybridization and SP-PCR study. 38
9572688 1998
139
Balanitis xerotica obliterans in monozygotic twins. 38
9439431 1997
140
Balanitis xerotica obliterans in monozygotic twins. 38
9158529 1997
141
Full-thickness skin grafts from eyelids to penis, plus split-thickness grafts in chronic balanitis xerotica obliterans. 38
9043588 1997
142
Circumferential laser vaporization for severe meatal stenosis secondary to balanitis xerotica obliterans. 38
8863582 1996
143
Squamous cell carcinoma of the penis arising from balanitis xerotica obliterans. 38
8836794 1996
144
The detection of human papillomavirus deoxyribonucleic acid in intraepithelial, in situ, verrucous and invasive carcinoma of the penis. 38
7637047 1995
145
Detection of human papillomavirus types in balanitis xerotica obliterans and other penile conditions. 38
7590713 1995
146
Zosteriform atrophoderma of Pasini and Pierini. 38
7671424 1995
147
Balanitis xerotica obliterans. 38
7779935 1995
148
Lichen sclerosus. 38
7868709 1995
149
Dermacase. Balanitis xerotica obliterans. 38
7950467 1994
150
[Acquired phimosis due to lichen sclerosus et atrophicus]. 38
7946989 1994
151
The treatment of childhood phimosis with topical steroid. 38
8179528 1994
152
Composition of the inflammatory infiltrate in pediatric penile lichen sclerosus et atrophicus (balanitis xerotica obliterans): a prospective, comparative immunophenotyping study. 38
8008686 1994
153
Recurrent bullous balanitis: an unusual presentation of balanitis xerotica obliterans. 38
8142531 1994
154
Penile squamous cell carcinoma arising from balanitis xerotica obliterans. 38
8349865 1993
155
Histopathological and immunological studies in a cohort of balanitis xerotica obliterans. 38
8409501 1993
156
Inappropriate circumcision referrals by GPs. 38
1625262 1992
157
Premalignant and early carcinomas of the penis and scrotum. 38
1574813 1992
158
Squamous cell carcinoma and lichen sclerosus et atrophicus of the prepuce. 38
1561268 1992
159
Balanitis and balanoposthitis. 38
1736474 1992
160
Premalignant lesions and nonsquamous malignancy of the penis and carcinoma of the scrotum. 38
1736473 1992
161
In situ localization of interleukin-6 in normal skin and atrophic cutaneous disease. 38
1343091 1992
162
Chordee without hypospadias: experience with 33 cases. 38
1729493 1992
163
[Acquired phimosis, or preputial sclero-atrophic lichen in children]. 38
1960184 1991
164
Carcinoma of the penis in lichen sclerosus atrophicus. A case report. 38
2226586 1990
165
[Atrophicus sclerosis lichen and cancer of the glans]. 38
2687396 1989
166
Urethral strictures in childhood. 38
3219514 1988
167
Balanitis xerotica obliterans: surgical treatment. 38
3360038 1988
168
Persistent bullae on the penis of an elderly man. Balanitis xerotica obliterans. 38
3662575 1987
169
Verrucous carcinoma in penile lichen sclerosus et atrophicus. 38
2437168 1987
170
Balanitis xerotica obliterans in children. 38
3449818 1987
171
Adenosquamous carcinoma of the penis associated with balanitis xerotica obliterans. 38
3801839 1986
172
Balanitis xerotica obliterans on stump of amputated penis. 38
3756417 1986
173
Balanitis xerotica obliterans in children. 38
3735511 1986
174
[Balanitis xerotica obliterans in childhood. Apropos of a case in a 11-year-old boy and review of the literature]. 38
3744426 1986
175
Carbon dioxide laser treatment of external genital lesions. 38
3925610 1985
176
Carbon dioxide laser treatment of balanitis xerotica obliterans. 38
6725681 1984
177
Surgical treatment of balanitis xerotica obliterans. 38
6538689 1984
178
Meatoplasty for gross urethral stenosis: a technique of repair and a review of 32 cases. 38
6692054 1984
179
Treatment of localized scleroderma and lichen sclerosus with etretinate. 38
6203311 1984
180
Point of focus: poor genital hygiene and terminal urethral strictures. 38
6612780 1983
181
Continuous wave carbon dioxide treatment of balanitis xerotica obliterans. 38
6805123 1982
182
Cancers, precancers, and pseudocancers on the male genitalia. A review of clinical appearances, histopathology, and management. 38
6259230 1980
183
Phimosis in boys. 38
7191744 1980
184
Lichen sclerosus et atrophicus, multiple dysplastic keratoses, and squamous-cell carcinoma of the glans penis. 38
7356699 1980
185
Balanitis xerotica obliterans involving anterior urethra. 38
516213 1979
186
[Balanitis xerotica obliterans (author's transl)]. 38
509272 1979
187
Balanitis xerotica obliterans. 38
465992 1979
188
Tumor conference No 18: squamous-cell carcinoma arising in balanitis xerotica obliterans. 38
690306 1978
189
Urethro-balanitis xerotica obliterans. 38
627227 1978
190
[Balanitis xerotica obliterans following Stuhmer's operation]. 38
868603 1977
191
The treatment of balanitis xerotica obliterans with testosterone propionate ointment. 38
71837 1977
192
Balanitis xerotica obliterans in children. 38
1237636 1975
193
[Surgical treatment of penile lichen sclerosus et atrophicus]. 38
4777754 1973
194
Balanitis xerotica obliterans: report of a case in an 11-year-old and review of the literature. 38
4724440 1973
195
[Leukokeratosis and kraurosis of the penis and balanitis xerotica obliterans (a review of the literature)]. 38
4585663 1973
196
Balanitis xerotica obliterans and urinary obstruction. 38
5095580 1971
197
Balanitis xerotica obliterans. 38
5532914 1970
198
[Balanitis xerotica obliterans. A review and a description of 10 cases]. 38
4911649 1970
199
Urethral involvement in balanitis xerotica obliterans. 38
5420163 1970
200
[Sclerosing genital atrophy as the cause of phimosis: kraurosis penis--balanitis xerotica obliterans--lichen sclerosus et atrophicus]. 38
5730915 1968
201
Balanitis xerotica obliterans: effective treatment with topical and sublesional corticosteroids. 38
6058157 1967
202
[LICHEN SCLEROSUS ET ATROPHICUS, KRAUROSIS VULVAE AND BALANITIS XEROTICA OBLITERANS]. 38
14191293 1964
203
[POSTOPERATIVE BALANITIS XEROTICA OBLITERANS (STUEHMER) AND ITS IDENTITY WITH DELBANCO'S KRAUROSIS PENIS ET PRAEPUTII]. 38
14108362 1963
204
Treatment of balanitis xerotica obliterans with hydrocortisone injections. 38
13877396 1962
205
Balanitis xerotica obliterans manifesting on stump of amputated penis; report of an unusual case and remarks on the nature of lichen sclerosus et atrophicus. 38
13636433 1959
206
[Balanitis xerotica obliterans (post-operative) of Stühmer]. 38
13331250 1956
207
[Balanitis xerotica obliterans; a new etiological factor]. 38
13408600 1956
208
Balanitis xerotica obliterans. 38
13244849 1955
209
A case of balanitis xerotica obliterans with telangiectasis responding to intravenous procaine. 38
14382189 1955
210
Balanitis xerotica obliterans; or kraurosis penis. 38
13223595 1955
211
Balanitis xerotica obliterans; a case report. 38
13152866 1954
212
Balanitis xerotica obliterans: management of the stricture. 38
14384837 1954
213
Balanitis xerotica obliterans. 38
13267920 1954
214
[Stenosis of the urethral meatus and of the first portion of the urethra in inflammatory phimosis; balanitis xerotica obliterans]. 38
13063338 1953
215
Balanitis xerotica obliterans. 38
15407359 1949
216
Balanitis xerotica obliterans; report of a case. 38
18151074 1949
217
Balanitis xerotica obliterans; a report of two cases. 38
18118775 1949
218
Balanitis xerotica obliterans. 38
18098689 1948
219
Balanitis xerotica obliterans. 38
20262884 1947
220
Balanitis xerotica obliterans; report of a case. 38
20283482 1947
221
Balanitis xerotica obliterans; a report of two cases. 38
20290779 1947
222
Balanitis xerotica obliterans associated with chronic gonorrhea. 38
20279613 1946
223
Balanitis xerotica obliterans. 38
20992329 1946
224
Balanitis Xerotica Obliterans. 38
19993330 1946
225
Balanitis xerotica obliterans. 38
21064999 1946

Variations for Balanitis Xerotica Obliterans

Expression for Balanitis Xerotica Obliterans

Search GEO for disease gene expression data for Balanitis Xerotica Obliterans.

Pathways for Balanitis Xerotica Obliterans

GO Terms for Balanitis Xerotica Obliterans

Biological processes related to Balanitis Xerotica Obliterans according to GeneCards Suite gene sharing:

(showing 5, show less)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of apoptotic process GO:0043065 9.56 TP53 TGM2 PTGS2 CDKN2A
2 cellular response to hypoxia GO:0071456 9.5 VEGFA TP53 PTGS2
3 replicative senescence GO:0090399 9.16 TP53 CDKN2A
4 peptide cross-linking GO:0018149 9.13 TGM3 TGM2 TGM1
5 cell envelope organization GO:0043163 8.62 TGM3 TGM1

Molecular functions related to Balanitis Xerotica Obliterans according to GeneCards Suite gene sharing:

(showing 3, show less)
# Name GO ID Score Top Affiliating Genes
1 extracellular matrix binding GO:0050840 9.16 VEGFA ELN
2 transferase activity, transferring acyl groups GO:0016746 9.13 TGM3 TGM2 TGM1
3 protein-glutamine gamma-glutamyltransferase activity GO:0003810 8.8 TGM3 TGM2 TGM1

Sources for Balanitis Xerotica Obliterans

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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