MCID: BRT014
MIFTS: 33

Bartholin's Duct Cyst

Categories: Endocrine diseases, Reproductive diseases

Aliases & Classifications for Bartholin's Duct Cyst

MalaCards integrated aliases for Bartholin's Duct Cyst:

Name: Bartholin's Duct Cyst 12 15
Cyst of Bartholin's Gland Duct 12 74
Cyst of Bartholin's Gland 12
Bartholin Duct Cyst 12
Bartholin's Cyst 12

Classifications:



External Ids:

Disease Ontology 12 DOID:851
ICD9CM 36 616.2
NCIt 51 C26706
SNOMED-CT 69 27978000 57044006
ICD10 34 N75.0
UMLS 74 C0004767

Summaries for Bartholin's Duct Cyst

Disease Ontology : 12 A female reproductive system disease that is characterized by a fluid-filled swelling in the Bartholin's glands.

MalaCards based summary : Bartholin's Duct Cyst, also known as cyst of bartholin's gland duct, is related to gastric signet ring cell adenocarcinoma and cystitis cystica. An important gene associated with Bartholin's Duct Cyst is GATA3 (GATA Binding Protein 3), and among its related pathways/superpathways are Deubiquitination and Interleukin-4 and 13 signaling. The drugs silver nitrate and Anti-Infective Agents, Local have been mentioned in the context of this disorder. Related phenotypes are cellular and digestive/alimentary

Wikipedia : 77 A Bartholin''s cyst occurs when Bartholin''s gland, within the labia, becomes blocked. Small cysts may... more...

Related Diseases for Bartholin's Duct Cyst

Diseases related to Bartholin's Duct Cyst via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 56)
# Related Disease Score Top Affiliating Genes
1 gastric signet ring cell adenocarcinoma 10.1 GATA3 PIP
2 cystitis cystica 10.1 AR GATA3
3 oncocytic breast carcinoma 10.1 AR PIP
4 paget disease, extramammary 10.1 AR PIP
5 papillary hidradenoma 10.1 AR PIP
6 sarcomatoid renal cell carcinoma 10.1 GATA3 TP53
7 microglandular adenosis 10.0 PIP TP53
8 sweat gland cancer 10.0 GATA3 TP53
9 breast benign neoplasm 10.0 PIP TP53
10 thoracic benign neoplasm 10.0 PIP TP53
11 hidradenocarcinoma 10.0 PIP TP53
12 pre-malignant neoplasm 10.0 PIP TP53
13 leukemia, acute lymphoblastic 3 10.0 GATA3 TP53
14 female breast cancer 10.0 AR TP53
15 adenosquamous carcinoma 10.0 AR TP53
16 ductal carcinoma in situ 10.0 AR TP53
17 endometrial adenocarcinoma 10.0
18 adenocarcinoma 10.0
19 male reproductive organ cancer 10.0 AR TP53
20 pleomorphic adenoma 10.0 AR TP53
21 male reproductive system disease 10.0 AR TP53
22 gonadal disease 9.9 AR TP53
23 testicular germ cell tumor 9.9 AR TP53
24 eccrine adenocarcinoma 9.9 PIP SMUG1
25 prostate disease 9.9 AR TP53
26 malignant spiradenoma 9.9 SMUG1 TP53
27 cellular ependymoma 9.9 SMUG1 TP53
28 protoplasmic astrocytoma 9.9 SMUG1 TP53
29 colloid adenoma 9.9 SMUG1 TP53
30 mature teratoma 9.9 SMUG1 TP53
31 prostate squamous cell carcinoma 9.9 SMUG1 TP53
32 central nervous system hematologic cancer 9.9 SMUG1 TP53
33 suppression of tumorigenicity 12 9.9 AR TP53
34 xanthogranulomatous cholecystitis 9.8 SMUG1 TP53
35 oropharynx cancer 9.8 SMUG1 TP53
36 pharynx cancer 9.8 SMUG1 TP53
37 nasopharyngeal disease 9.8 SMUG1 TP53
38 esophageal disease 9.8 SMUG1 TP53
39 connective tissue cancer 9.8 SMUG1 TP53
40 cervix disease 9.8 SMUG1 TP53
41 uterine anomalies 9.8 SMUG1 TP53
42 leukocyte disease 9.8 SMUG1 TP53
43 thymus cancer 9.8 SMUG1 TP53
44 female reproductive system disease 9.8 SMUG1 TP53
45 respiratory system cancer 9.8 SMUG1 TP53
46 breast ductal carcinoma 9.8 AR PIP TP53
47 intestinal disease 9.7 SMUG1 TP53
48 gastrointestinal system cancer 9.7 SMUG1 TP53
49 respiratory system disease 9.7 SMUG1 TP53
50 meningioma, familial 9.7 SMUG1 TP53

Graphical network of the top 20 diseases related to Bartholin's Duct Cyst:



Diseases related to Bartholin's Duct Cyst

Symptoms & Phenotypes for Bartholin's Duct Cyst

MGI Mouse Phenotypes related to Bartholin's Duct Cyst:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.72 AR GATA3 PIP SMUG1 TP53
2 digestive/alimentary MP:0005381 9.56 AR GATA3 PIP TP53
3 endocrine/exocrine gland MP:0005379 9.46 AR GATA3 PIP TP53
4 pigmentation MP:0001186 9.13 AR GATA3 TP53
5 reproductive system MP:0005389 8.92 AR GATA3 PIP TP53

Drugs & Therapeutics for Bartholin's Duct Cyst

Drugs for Bartholin's Duct Cyst (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 silver nitrate Approved, Investigational Phase 4
2 Anti-Infective Agents, Local Phase 4
3 Anti-Infective Agents Phase 4
4 Anesthetics Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Treatment of Bartholin´s Cyst or Abscess With Silver Nitrate Unknown status NCT00786461 Phase 4

Search NIH Clinical Center for Bartholin's Duct Cyst

Genetic Tests for Bartholin's Duct Cyst

Anatomical Context for Bartholin's Duct Cyst

Publications for Bartholin's Duct Cyst

Articles related to Bartholin's Duct Cyst:

# Title Authors Year
1
Urinary retention as the presentation of Bartholin's duct cyst in a neonate. ( 22578485 )
2012
2
MR findings of a giant Bartholin's duct cyst. ( 18603842 )
2008
3
Management of Bartholin's duct cyst and gland abscess. ( 12887119 )
2003

Variations for Bartholin's Duct Cyst

Expression for Bartholin's Duct Cyst

Search GEO for disease gene expression data for Bartholin's Duct Cyst.

Pathways for Bartholin's Duct Cyst

Pathways related to Bartholin's Duct Cyst according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.52 AR GATA3 TP53
2 11.31 GATA3 TP53
3 11.07 GATA3 TP53
4 10.84 AR GATA3

GO Terms for Bartholin's Duct Cyst

Cellular components related to Bartholin's Duct Cyst according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nuclear chromatin GO:0000790 8.8 AR GATA3 TP53

Biological processes related to Bartholin's Duct Cyst according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of transcription by RNA polymerase II GO:0000122 9.63 AR GATA3 TP53
2 positive regulation of transcription, DNA-templated GO:0045893 9.58 AR GATA3 TP53
3 negative regulation of cell proliferation GO:0008285 9.54 AR GATA3 TP53
4 male gonad development GO:0008584 9.43 AR GATA3
5 positive regulation of cell differentiation GO:0045597 9.32 AR GATA3
6 base-excision repair GO:0006284 9.26 SMUG1 TP53
7 response to gamma radiation GO:0010332 9.16 GATA3 TP53
8 protein deubiquitination GO:0016579 9.13 AR GATA3 TP53
9 positive regulation of gene expression GO:0010628 8.92 AR GATA3 PIP TP53

Molecular functions related to Bartholin's Duct Cyst according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA binding GO:0003677 9.67 AR GATA3 SMUG1 TP53
2 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 9.5 AR GATA3 TP53
3 transcription factor binding GO:0008134 9.33 AR GATA3 TP53
4 RNA polymerase II transcription factor binding GO:0001085 9.26 AR TP53
5 transcription regulatory region DNA binding GO:0044212 9.13 AR GATA3 TP53
6 protein dimerization activity GO:0046983 8.8 AR GATA3 PIP

Sources for Bartholin's Duct Cyst

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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