MCID: BRT014
MIFTS: 35

Bartholin's Duct Cyst

Categories: Endocrine diseases, Reproductive diseases

Aliases & Classifications for Bartholin's Duct Cyst

MalaCards integrated aliases for Bartholin's Duct Cyst:

Name: Bartholin's Duct Cyst 12 15
Cyst of Bartholin's Gland Duct 12 74
Cyst of Bartholin's Gland 12
Bartholin Duct Cyst 12
Bartholin's Cyst 12

Classifications:



External Ids:

Disease Ontology 12 DOID:851
ICD9CM 36 616.2
NCIt 51 C26706
SNOMED-CT 69 27978000 57044006
ICD10 34 N75.0
UMLS 74 C0004767

Summaries for Bartholin's Duct Cyst

Disease Ontology : 12 A female reproductive system disease that is characterized by a fluid-filled swelling in the Bartholin's glands.

MalaCards based summary : Bartholin's Duct Cyst, also known as cyst of bartholin's gland duct, is related to gastric signet ring cell adenocarcinoma and oncocytic breast carcinoma. An important gene associated with Bartholin's Duct Cyst is GATA3 (GATA Binding Protein 3), and among its related pathways/superpathways are Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways and Factors involved in megakaryocyte development and platelet production. The drugs silver nitrate and Anesthetics have been mentioned in the context of this disorder. Affiliated tissues include breast and prostate, and related phenotypes are cardiovascular system and cellular

Wikipedia : 77 A Bartholin''s cyst occurs when Bartholin''s gland, within the labia, becomes blocked. Small cysts may... more...

Related Diseases for Bartholin's Duct Cyst

Graphical network of the top 20 diseases related to Bartholin's Duct Cyst:



Diseases related to Bartholin's Duct Cyst

Symptoms & Phenotypes for Bartholin's Duct Cyst

MGI Mouse Phenotypes related to Bartholin's Duct Cyst:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.76 AR GATA3 PIP TP53
2 cellular MP:0005384 9.73 AR GATA3 PIP TP53
3 digestive/alimentary MP:0005381 9.67 AR GATA3 PIP TP53
4 adipose tissue MP:0005375 9.65 AR GATA3 TP53
5 endocrine/exocrine gland MP:0005379 9.62 AR GATA3 PIP TP53
6 craniofacial MP:0005382 9.58 AR GATA3 TP53
7 hematopoietic system MP:0005397 9.56 AR GATA3 PIP TP53
8 immune system MP:0005387 9.46 AR GATA3 PIP TP53
9 pigmentation MP:0001186 9.13 AR GATA3 TP53
10 reproductive system MP:0005389 8.92 AR GATA3 PIP TP53

Drugs & Therapeutics for Bartholin's Duct Cyst

Drugs for Bartholin's Duct Cyst (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 silver nitrate Approved, Investigational Phase 4
2 Anesthetics Phase 4
3 Anti-Infective Agents, Local Phase 4
4 Anti-Infective Agents Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Treatment of Bartholin´s Cyst or Abscess With Silver Nitrate Unknown status NCT00786461 Phase 4

Search NIH Clinical Center for Bartholin's Duct Cyst

Genetic Tests for Bartholin's Duct Cyst

Anatomical Context for Bartholin's Duct Cyst

MalaCards organs/tissues related to Bartholin's Duct Cyst:

42
Breast, Prostate

Publications for Bartholin's Duct Cyst

Articles related to Bartholin's Duct Cyst:

# Title Authors Year
1
Urinary retention as the presentation of Bartholin's duct cyst in a neonate. ( 22578485 )
2012
2
MR findings of a giant Bartholin's duct cyst. ( 18603842 )
2008
3
Management of Bartholin's duct cyst and gland abscess. ( 12887119 )
2003

Variations for Bartholin's Duct Cyst

Expression for Bartholin's Duct Cyst

Search GEO for disease gene expression data for Bartholin's Duct Cyst.

Pathways for Bartholin's Duct Cyst

GO Terms for Bartholin's Duct Cyst

Cellular components related to Bartholin's Duct Cyst according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nuclear chromatin GO:0000790 8.8 AR GATA3 TP53

Biological processes related to Bartholin's Duct Cyst according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription by RNA polymerase II GO:0045944 9.63 AR GATA3 TP53
2 negative regulation of transcription by RNA polymerase II GO:0000122 9.61 AR GATA3 TP53
3 positive regulation of transcription, DNA-templated GO:0045893 9.54 AR GATA3 TP53
4 negative regulation of cell proliferation GO:0008285 9.5 AR GATA3 TP53
5 in utero embryonic development GO:0001701 9.48 AR GATA3
6 male gonad development GO:0008584 9.4 AR GATA3
7 positive regulation of cell differentiation GO:0045597 9.26 AR GATA3
8 response to gamma radiation GO:0010332 9.16 GATA3 TP53
9 protein deubiquitination GO:0016579 9.13 AR GATA3 TP53
10 positive regulation of gene expression GO:0010628 8.92 AR GATA3 PIP TP53

Molecular functions related to Bartholin's Duct Cyst according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA-binding transcription factor activity GO:0003700 9.58 AR GATA3 TP53
2 zinc ion binding GO:0008270 9.54 AR GATA3 TP53
3 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 9.5 AR GATA3 TP53
4 transcription factor binding GO:0008134 9.33 AR GATA3 TP53
5 RNA polymerase II transcription factor binding GO:0001085 9.26 AR TP53
6 transcription regulatory region DNA binding GO:0044212 9.13 AR GATA3 TP53
7 protein dimerization activity GO:0046983 8.8 AR GATA3 PIP

Sources for Bartholin's Duct Cyst

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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