MCID: BRT014
MIFTS: 37

Bartholin's Duct Cyst

Categories: Endocrine diseases, Reproductive diseases

Aliases & Classifications for Bartholin's Duct Cyst

MalaCards integrated aliases for Bartholin's Duct Cyst:

Name: Bartholin's Duct Cyst 12 15
Cyst of Bartholin's Gland Duct 12 73
Cyst of Bartholin's Gland 12
Bartholin Duct Cyst 12
Bartholin's Cyst 12

Classifications:



External Ids:

Disease Ontology 12 DOID:851
ICD10 33 N75.0
ICD9CM 35 616.2
NCIt 50 C26706
SNOMED-CT 68 27978000 57044006
UMLS 73 C0004767

Summaries for Bartholin's Duct Cyst

Disease Ontology : 12 A female reproductive system disease that is characterized by a fluid-filled swelling in the Bartholin's glands.

MalaCards based summary : Bartholin's Duct Cyst, also known as cyst of bartholin's gland duct, is related to gastric signet ring cell adenocarcinoma and cystitis cystica. An important gene associated with Bartholin's Duct Cyst is GATA3 (GATA Binding Protein 3), and among its related pathways/superpathways are Deubiquitination and Pyrimidine metabolism. The drugs silver nitrate and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include colon, breast and prostate, and related phenotypes are cellular and digestive/alimentary

Wikipedia : 76 A Bartholin''s cyst occurs when Bartholin''s gland, within the labia, becomes blocked. Small cysts may... more...

Related Diseases for Bartholin's Duct Cyst

Diseases related to Bartholin's Duct Cyst via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 54)
# Related Disease Score Top Affiliating Genes
1 gastric signet ring cell adenocarcinoma 10.1 GATA3 PIP
2 cystitis cystica 10.1 AR GATA3
3 oncocytic breast carcinoma 10.1 AR PIP
4 paget disease, extramammary 10.1 AR PIP
5 papillary hidradenoma 10.1 AR PIP
6 microglandular adenosis 10.0 PIP TP53
7 sweat gland cancer 10.0 GATA3 TP53
8 breast benign neoplasm 10.0 PIP TP53
9 thoracic benign neoplasm 10.0 PIP TP53
10 hidradenocarcinoma 10.0 PIP TP53
11 leukemia, acute lymphoblastic 3 10.0 GATA3 TP53
12 pre-malignant neoplasm 10.0 PIP TP53
13 female breast cancer 10.0 AR TP53
14 adenosquamous carcinoma 10.0 AR TP53
15 ductal carcinoma in situ 10.0 AR TP53
16 male reproductive organ cancer 10.0 AR TP53
17 pleomorphic adenoma 10.0 AR TP53
18 male reproductive system disease 10.0 AR TP53
19 gonadal disease 10.0 AR TP53
20 eccrine adenocarcinoma 10.0 PIP SMUG1
21 prostate disease 9.9 AR TP53
22 malignant spiradenoma 9.9 SMUG1 TP53
23 cellular ependymoma 9.9 SMUG1 TP53
24 protoplasmic astrocytoma 9.9 SMUG1 TP53
25 colloid adenoma 9.9 SMUG1 TP53
26 mature teratoma 9.9 SMUG1 TP53
27 prostate squamous cell carcinoma 9.9 SMUG1 TP53
28 central nervous system hematologic cancer 9.9 SMUG1 TP53
29 suppression of tumorigenicity 12 9.9 AR TP53
30 xanthogranulomatous cholecystitis 9.9 SMUG1 TP53
31 oropharynx cancer 9.9 SMUG1 TP53
32 pharynx cancer 9.9 SMUG1 TP53
33 nasopharyngeal disease 9.9 SMUG1 TP53
34 esophageal disease 9.9 SMUG1 TP53
35 connective tissue cancer 9.9 SMUG1 TP53
36 cervix disease 9.9 SMUG1 TP53
37 uterine anomalies 9.9 SMUG1 TP53
38 leukocyte disease 9.9 SMUG1 TP53
39 thymus cancer 9.9 SMUG1 TP53
40 bladder urothelial carcinoma 9.9 AR GATA3 TP53
41 female reproductive system disease 9.9 SMUG1 TP53
42 rectal neoplasm 9.8 SMUG1 TP53
43 respiratory system cancer 9.8 SMUG1 TP53
44 breast ductal carcinoma 9.8 AR PIP TP53
45 intestinal disease 9.8 SMUG1 TP53
46 respiratory system disease 9.8 SMUG1 TP53
47 gastrointestinal system cancer 9.8 SMUG1 TP53
48 meningioma, familial 9.8 SMUG1 TP53
49 gastrointestinal system disease 9.8 SMUG1 TP53
50 reproductive system disease 9.7 AR SMUG1 TP53

Graphical network of the top 20 diseases related to Bartholin's Duct Cyst:



Diseases related to Bartholin's Duct Cyst

Symptoms & Phenotypes for Bartholin's Duct Cyst

MGI Mouse Phenotypes related to Bartholin's Duct Cyst:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.72 AR GATA3 PIP SMUG1 TP53
2 digestive/alimentary MP:0005381 9.56 AR GATA3 PIP TP53
3 endocrine/exocrine gland MP:0005379 9.46 AR GATA3 PIP TP53
4 pigmentation MP:0001186 9.13 AR GATA3 TP53
5 reproductive system MP:0005389 8.92 AR GATA3 PIP TP53

Drugs & Therapeutics for Bartholin's Duct Cyst

Drugs for Bartholin's Duct Cyst (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 silver nitrate Approved, Investigational Phase 4
2 Anti-Infective Agents Phase 4
3 Anti-Infective Agents, Local Phase 4
4 Anesthetics Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Treatment of Bartholin´s Cyst or Abscess With Silver Nitrate Unknown status NCT00786461 Phase 4

Search NIH Clinical Center for Bartholin's Duct Cyst

Genetic Tests for Bartholin's Duct Cyst

Anatomical Context for Bartholin's Duct Cyst

MalaCards organs/tissues related to Bartholin's Duct Cyst:

41
Colon, Breast, Prostate, Pancreas, Cervix, Thymus

Publications for Bartholin's Duct Cyst

Articles related to Bartholin's Duct Cyst:

# Title Authors Year
1
Urinary retention as the presentation of Bartholin's duct cyst in a neonate. ( 22578485 )
2012
2
MR findings of a giant Bartholin's duct cyst. ( 18603842 )
2008
3
Management of Bartholin's duct cyst and gland abscess. ( 12887119 )
2003

Variations for Bartholin's Duct Cyst

Expression for Bartholin's Duct Cyst

Search GEO for disease gene expression data for Bartholin's Duct Cyst.

Pathways for Bartholin's Duct Cyst

GO Terms for Bartholin's Duct Cyst

Cellular components related to Bartholin's Duct Cyst according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nuclear chromatin GO:0000790 8.8 AR GATA3 TP53

Biological processes related to Bartholin's Duct Cyst according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of transcription by RNA polymerase II GO:0000122 9.63 AR GATA3 TP53
2 positive regulation of transcription, DNA-templated GO:0045893 9.58 AR GATA3 TP53
3 negative regulation of cell proliferation GO:0008285 9.54 AR GATA3 TP53
4 male gonad development GO:0008584 9.43 AR GATA3
5 positive regulation of cell differentiation GO:0045597 9.32 AR GATA3
6 base-excision repair GO:0006284 9.26 SMUG1 TP53
7 response to gamma radiation GO:0010332 9.16 GATA3 TP53
8 protein deubiquitination GO:0016579 9.13 AR GATA3 TP53
9 positive regulation of gene expression GO:0010628 8.92 AR GATA3 PIP TP53

Molecular functions related to Bartholin's Duct Cyst according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA binding GO:0003677 9.67 AR GATA3 SMUG1 TP53
2 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 9.5 AR GATA3 TP53
3 transcription factor binding GO:0008134 9.33 AR GATA3 TP53
4 RNA polymerase II transcription factor binding GO:0001085 9.26 AR TP53
5 transcription regulatory region DNA binding GO:0044212 9.13 AR GATA3 TP53
6 protein dimerization activity GO:0046983 8.8 AR GATA3 PIP

Sources for Bartholin's Duct Cyst

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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