MCID: BRT008
MIFTS: 28

Bartholin's Gland Adenoid Cystic Carcinoma

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases
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Aliases & Classifications for Bartholin's Gland Adenoid Cystic Carcinoma

MalaCards integrated aliases for Bartholin's Gland Adenoid Cystic Carcinoma:

Name: Bartholin's Gland Adenoid Cystic Carcinoma 11 14
Bartholin Gland Adenoid Cystic Carcinoma 11 71

Classifications:



External Ids:

Disease Ontology 11 DOID:4879
NCIt 49 C40295
UMLS 71 C1511047

Summaries for Bartholin's Gland Adenoid Cystic Carcinoma

Disease Ontology: 11 A Bartholin's gland carcinoma that is characterized by a distinctive pattern in which abnormal nests and columns of cells of bland appearance are arranged concentrically around glandlike spaces filled with eosinophilic periodic acid-Schiff-positive diastase-resistant material.

MalaCards based summary: Bartholin's Gland Adenoid Cystic Carcinoma, also known as bartholin gland adenoid cystic carcinoma, is related to adenoid cystic carcinoma and bartholin's gland carcinoma, and has symptoms including pain An important gene associated with Bartholin's Gland Adenoid Cystic Carcinoma is MYBL1 (MYB Proto-Oncogene Like 1), and among its related pathways/superpathways are Chromatin organization and Toll-like receptor signaling pathway. Affiliated tissues include lung and brain, and related phenotypes are homeostasis/metabolism and growth/size/body region

Related Diseases for Bartholin's Gland Adenoid Cystic Carcinoma

Diseases related to Bartholin's Gland Adenoid Cystic Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 114)
# Related Disease Score Top Affiliating Genes
1 adenoid cystic carcinoma 27.5 SMARCA2 PIK3CA NFIB MYBL1 KRT7 KDM6A
2 bartholin's gland carcinoma 10.3
3 pleomorphic adenoma carcinoma 10.3 NFIB MYBL1
4 cerebellum cancer 10.2 SUFU MYBL1
5 small-cell carcinoma of the ovary of hypercalcemic type 10.2 SMARCA2 ARID1A
6 ovarian small cell carcinoma 10.1 SMARCA2 ARID1A
7 ceruminoma 10.1 MYBL1 KRT7
8 breast mucoepidermoid carcinoma 10.1 MYBL1 KRT7
9 ceruminous adenocarcinoma 10.1 MYBL1 KRT7
10 synchronous bilateral breast carcinoma 10.1 NFIB ATM
11 sublingual gland adenoid cystic carcinoma 10.1 NFIB KRT7
12 menke-hennekam syndrome 10.1 EP300 CREBBP
13 sublingual gland cancer 10.1 NFIB KRT7
14 breast secretory carcinoma 10.1 NFIB KRT7
15 cervical adenoid cystic carcinoma 10.1 NFIB KRT7
16 floating-harbor syndrome 10.1 SMARCA2 CREBBP
17 rubinstein-taybi syndrome 1 10.1 EP300 CREBBP
18 cornelia de lange syndrome 2 10.1 EP300 CREBBP
19 epithelial-myoepithelial carcinoma 10.1 NFIB KRT7
20 oculomotor apraxia 10.1 SUFU ATM
21 myoepithelial carcinoma 10.1 NFIB KRT7
22 malignant spiradenoma 10.1 KRT7 CYLD
23 cribriform carcinoma 10.1 NFIB KRT7
24 secretory meningioma 10.1 SUFU KRT7
25 sinonasal undifferentiated carcinoma 10.1 SMARCA2 KRT7
26 rare genetic intellectual disability 10.0 EP300 CREBBP
27 clark-baraitser syndrome 10.0 SMARCA2 ARID1A
28 neurilemmomatosis 10.0 SUFU SMARCA2 ARID1A
29 paranasal sinus cancer 10.0 SMARCA2 KRT7
30 lacrimal gland carcinoma 10.0 NFIB KRT7
31 familial isolated trichomegaly 10.0 SMARCA2 KDM6A CREBBP
32 otopalatodigital syndrome, type i 10.0 EP300 CREBBP
33 adenofibroma 10.0 KRT7 ARID1A
34 otopalatodigital syndrome spectrum disorder 10.0 EP300 CREBBP
35 ovarian seromucinous carcinoma 10.0 KRT7 ARID1A
36 sweat gland benign neoplasm 10.0 KRT7 CYLD
37 lung adenoid cystic carcinoma 10.0 NFIB MYBL1 KRT7
38 medullary colon carcinoma 10.0 KRT7 ARID1A
39 breast adenoid cystic carcinoma 10.0 NFIB MYBL1 KRT7
40 nasal cavity cancer 10.0 SMARCA2 KRT7
41 eccrine adenocarcinoma 10.0 MYBL1 KRT7 CYLD
42 spiradenoma 9.9 NFIB KRT7 CYLD
43 charge syndrome 9.9 SMARCA2 KDM6A EP300
44 acinar cell carcinoma 9.9 NFIB KRT7
45 apocrine sweat gland neoplasm 9.9 NFIB KRT7 CYLD
46 hypertrichosis 9.9 SMARCA2 CREBBP ARID1A
47 brooke-spiegler syndrome 9.9 NFIB KRT7 CYLD
48 autosomal dominant intellectual developmental disorder 31 9.9 KDM6A EP300 CREBBP
49 clear cell adenofibroma 9.9 PIK3CA ARID1A
50 kabuki syndrome 1 9.9 KDM6A EP300 CREBBP

Graphical network of the top 20 diseases related to Bartholin's Gland Adenoid Cystic Carcinoma:



Diseases related to Bartholin's Gland Adenoid Cystic Carcinoma

Symptoms & Phenotypes for Bartholin's Gland Adenoid Cystic Carcinoma

UMLS symptoms related to Bartholin's Gland Adenoid Cystic Carcinoma:


pain

MGI Mouse Phenotypes related to Bartholin's Gland Adenoid Cystic Carcinoma:

45 (show all 15)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.27 ARID1A ATM CREBBP CYLD EP300 KDM6A
2 growth/size/body region MP:0005378 10.22 ARID1A ATM CREBBP CYLD EP300 KDM6A
3 neoplasm MP:0002006 10.2 ARID1A ATM CREBBP CYLD EP300 KDM6A
4 nervous system MP:0003631 10.13 ARID1A ATM CREBBP EP300 KDM6A NFIB
5 endocrine/exocrine gland MP:0005379 10.11 ARID1A ATM CREBBP CYLD EP300 MYBL1
6 normal MP:0002873 10.08 ARID1A CREBBP CYLD EP300 KDM6A MYBL1
7 cellular MP:0005384 10.02 ARID1A ATM CREBBP CYLD EP300 KDM6A
8 digestive/alimentary MP:0005381 10.01 CREBBP CYLD EP300 KDM6A NFIB PIK3CA
9 muscle MP:0005369 9.99 ARID1A CREBBP EP300 KDM6A PIK3CA SMARCA2
10 embryo MP:0005380 9.98 ARID1A ATM CREBBP EP300 KDM6A PIK3CA
11 immune system MP:0005387 9.91 ARID1A ATM CREBBP CYLD EP300 KDM6A
12 craniofacial MP:0005382 9.85 ARID1A CREBBP EP300 KDM6A NFIB SUFU
13 mortality/aging MP:0010768 9.65 ARID1A ATM CREBBP CYLD EP300 KDM6A
14 respiratory system MP:0005388 9.63 CREBBP CYLD EP300 KDM6A NFIB SUFU
15 integument MP:0010771 9.17 ATM CREBBP CYLD MYBL1 PIK3CA SMARCA2

Drugs & Therapeutics for Bartholin's Gland Adenoid Cystic Carcinoma

Search Clinical Trials, NIH Clinical Center for Bartholin's Gland Adenoid Cystic Carcinoma

Genetic Tests for Bartholin's Gland Adenoid Cystic Carcinoma

Anatomical Context for Bartholin's Gland Adenoid Cystic Carcinoma

Organs/tissues related to Bartholin's Gland Adenoid Cystic Carcinoma:

MalaCards : Lung, Brain

Publications for Bartholin's Gland Adenoid Cystic Carcinoma

Articles related to Bartholin's Gland Adenoid Cystic Carcinoma:

# Title Authors PMID Year
1
Brain and lung metastasis of Bartholin's gland adenoid cystic carcinoma: a case report. 62
23945057 2013

Variations for Bartholin's Gland Adenoid Cystic Carcinoma

Expression for Bartholin's Gland Adenoid Cystic Carcinoma

Search GEO for disease gene expression data for Bartholin's Gland Adenoid Cystic Carcinoma.

Pathways for Bartholin's Gland Adenoid Cystic Carcinoma

Pathways related to Bartholin's Gland Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

(show all 17)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.6 ARID1A CREBBP EP300 KDM6A SMARCA2
2
Show member pathways
12.55 PIK3CA EP300 CYLD CREBBP
3
Show member pathways
12.05 PIK3CA EP300 CREBBP
4 11.96 SMARCA2 KDM6A EP300 CREBBP ARID1A
5
Show member pathways
11.88 EP300 CREBBP ATM
6 11.69 PIK3CA EP300 CREBBP
7 11.42 EP300 CREBBP ATM
8 11.1 EP300 CREBBP
9
Show member pathways
11.1 SMARCA2 EP300 CREBBP ARID1A
10
Show member pathways
11.08 EP300 CREBBP
11 11.08 SMARCA2 EP300 ARID1A
12 11.07 SMARCA2 PIK3CA NFIB MYBL1 KDM6A EP300
13 11.04 EP300 CREBBP
14 10.87 CYLD ATM
15 10.78 EP300 CREBBP
16 10.73 EP300 CREBBP ATM
17 10.71 PIK3CA CREBBP

GO Terms for Bartholin's Gland Adenoid Cystic Carcinoma

Cellular components related to Bartholin's Gland Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nBAF complex GO:0071565 9.67 SMARCA2 ARID1A
2 npBAF complex GO:0071564 9.62 SMARCA2 ARID1A
3 brahma complex GO:0035060 9.56 SMARCA2 ARID1A
4 bBAF complex GO:0140092 9.46 SMARCA2 ARID1A
5 DNA packaging complex GO:0044815 8.96 SMARCA2 ARID1A
6 SWI/SNF superfamily-type complex GO:0070603 8.62 SMARCA2 ARID1A

Biological processes related to Bartholin's Gland Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of DNA-templated transcription GO:0006355 10.02 SUFU SMARCA2 NFIB MYBL1 EP300 CREBBP
2 positive regulation of DNA-templated transcription GO:0045893 9.93 ARID1A CREBBP EP300 MYBL1 NFIB SMARCA2
3 protein acetylation GO:0006473 9.67 EP300 CREBBP
4 multicellular organism growth GO:0035264 9.65 KDM6A EP300 ATM
5 N-terminal peptidyl-lysine acetylation GO:0018076 9.26 EP300 CREBBP
6 regulation of cellular response to heat GO:1900034 9.1 EP300 CREBBP ATM

Molecular functions related to Bartholin's Gland Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transcription coactivator activity GO:0003713 9.92 SMARCA2 EP300 CREBBP ARID1A
2 chromatin DNA binding GO:0031490 9.73 KDM6A EP300 CREBBP
3 1-phosphatidylinositol-3-kinase activity GO:0016303 9.46 PIK3CA ATM
4 peptide-lysine-N-acetyltransferase activity GO:0061733 9.26 EP300 CREBBP
5 peptide N-acetyltransferase activity GO:0034212 8.92 EP300 CREBBP

Sources for Bartholin's Gland Adenoid Cystic Carcinoma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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