MCID: BRT012
MIFTS: 27

Bartholin's Gland Adenoma

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Bartholin's Gland Adenoma

MalaCards integrated aliases for Bartholin's Gland Adenoma:

Name: Bartholin's Gland Adenoma 12 15
Bartholin Gland Adenoma 12 70

Classifications:



External Ids:

Disease Ontology 12 DOID:5382
NCIt 50 C40299
UMLS 70 C1511048

Summaries for Bartholin's Gland Adenoma

Disease Ontology : 12 A Bartholin's gland benign neoplasm that is characterized by glands or glandlike structures and has material basis in epithelial tissue.

MalaCards based summary : Bartholin's Gland Adenoma, also known as bartholin gland adenoma, is related to basaloid lung carcinoma and apocrine adenosis of breast. An important gene associated with Bartholin's Gland Adenoma is PGR (Progesterone Receptor), and among its related pathways/superpathways are Proteoglycans in cancer and Gastric cancer. Affiliated tissues include breast, ovary and lung, and related phenotypes are limbs/digits/tail and neoplasm

Related Diseases for Bartholin's Gland Adenoma

Diseases related to Bartholin's Gland Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 160)
# Related Disease Score Top Affiliating Genes
1 basaloid lung carcinoma 10.0 TP53 PGR
2 apocrine adenosis of breast 10.0 TP53 PGR
3 breast sarcoma 10.0 TP53 PGR
4 cervical adenoma malignum 10.0 TP53 PGR
5 peritoneal serous adenocarcinoma 10.0 TP53 PGR
6 primary peritoneal carcinoma 10.0 TP53 PGR
7 malignant spiradenoma 10.0 TP53 PGR
8 chordoid glioma 10.0 TP53 PGR
9 vulvar dystrophy 10.0 TP53 PGR
10 sweat gland benign neoplasm 10.0 TP53 PGR
11 papillary serous adenocarcinoma 10.0 TP53 PGR
12 pleomorphic carcinoma 10.0 TP53 PGR
13 papillary adenocarcinoma 9.9 TP53 PGR
14 oropharynx cancer 9.9 TP53 PGR
15 cervical adenocarcinoma 9.9 TP53 ESR1
16 serous cystadenocarcinoma 9.9 TP53 PGR
17 cystadenocarcinoma 9.9 TP53 PGR
18 carcinosarcoma 9.9 TP53 PGR
19 leiomyoma 9.9 PGR ESR1
20 uterine carcinosarcoma 9.9 TP53 PGR
21 ovarian serous cystadenocarcinoma 9.9 TP53 PGR
22 glassy cell carcinoma of the cervix 9.9 PGR ESR1
23 breast intraductal papillomatosis 9.9 PGR ESR1
24 familial ovarian cancer 9.9 TP53 ESR1
25 intraductal papilloma 9.9 PGR ESR1
26 nipple carcinoma 9.9 PGR ESR1
27 bartholin's gland adenoid cystic carcinoma 9.9 PGR ESR1
28 uterine corpus adenosarcoma 9.9 PGR ESR1
29 chronic tympanitis 9.9 PGR ESR1
30 granulomatous endometritis 9.9 PGR ESR1
31 endometritis 9.9 PGR ESR1
32 uterine body mixed cancer 9.9 TP53 ESR1
33 vulvar syringoma 9.9 PGR ESR1
34 lung leiomyoma 9.9 PGR ESR1
35 adult type testicular granulosa cell tumor 9.9 PGR ESR1
36 breast scirrhous carcinoma 9.9 PGR ESR1
37 oncocytic breast carcinoma 9.9 PGR ESR1
38 cervical clear cell adenocarcinoma 9.9 PGR ESR1
39 breast papillary carcinoma 9.9 PGR ESR1
40 papillary carcinoma 9.9 PGR ESR1
41 liver leiomyoma 9.9 PGR ESR1
42 intravenous leiomyomatosis 9.9 PGR ESR1
43 leiomyomatosis 9.9 PGR ESR1
44 breast adenoid cystic carcinoma 9.9 PGR ESR1
45 breast metaplastic carcinoma 9.9 PGR ESR1
46 intracranial meningioma 9.9 PGR ESR1
47 vulvar leiomyoma 9.9 PGR ESR1
48 breast adenoma 9.9 PGR ESR1
49 lipid-rich carcinoma 9.8 PGR ESR1
50 prostate stromal sarcoma 9.8 PGR ESR1

Graphical network of the top 20 diseases related to Bartholin's Gland Adenoma:



Diseases related to Bartholin's Gland Adenoma

Symptoms & Phenotypes for Bartholin's Gland Adenoma

MGI Mouse Phenotypes related to Bartholin's Gland Adenoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 limbs/digits/tail MP:0005371 9.33 ESR1 PGR TP53
2 neoplasm MP:0002006 9.13 ESR1 PGR TP53
3 no phenotypic analysis MP:0003012 8.8 ESR1 PGR TP53

Drugs & Therapeutics for Bartholin's Gland Adenoma

Search Clinical Trials , NIH Clinical Center for Bartholin's Gland Adenoma

Genetic Tests for Bartholin's Gland Adenoma

Anatomical Context for Bartholin's Gland Adenoma

MalaCards organs/tissues related to Bartholin's Gland Adenoma:

40
Breast, Ovary, Lung, Cervix, Salivary Gland, Bone, Smooth Muscle

Publications for Bartholin's Gland Adenoma

Articles related to Bartholin's Gland Adenoma:

# Title Authors PMID Year
1
Concomitant adenoma and hybrid carcinoma of salivary gland type arising in Bartholin's gland. 61
11109169 2000
2
Nodular hyperplasia, adenoma, and adenomyoma of Bartholin's gland. 61
9785128 1998

Variations for Bartholin's Gland Adenoma

Expression for Bartholin's Gland Adenoma

Search GEO for disease gene expression data for Bartholin's Gland Adenoma.

Pathways for Bartholin's Gland Adenoma

Pathways related to Bartholin's Gland Adenoma according to GeneCards Suite gene sharing:

(show all 11)
# Super pathways Score Top Affiliating Genes
1 11.81 TP53 ESR1
2
Show member pathways
11.8 TP53 PGR ESR1
3 11.66 TP53 ESR1
4 11.6 PGR ESR1
5 11.52 TP53 ESR1
6
Show member pathways
11.44 PGR ESR1
7
Show member pathways
11.32 PGR ESR1
8
Show member pathways
11.15 PGR ESR1
9 10.88 TP53 ESR1
10 10.72 TP53 ESR1
11 10.17 TP53 ESR1

GO Terms for Bartholin's Gland Adenoma

Cellular components related to Bartholin's Gland Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chromatin GO:0000785 8.8 TP53 PGR ESR1

Biological processes related to Bartholin's Gland Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription by RNA polymerase II GO:0045944 9.54 TP53 PGR ESR1
2 negative regulation of gene expression GO:0010629 9.43 TP53 PGR ESR1
3 transcription initiation from RNA polymerase II promoter GO:0006367 9.4 PGR ESR1
4 steroid hormone mediated signaling pathway GO:0043401 9.32 PGR ESR1
5 negative regulation of production of miRNAs involved in gene silencing by miRNA GO:1903799 9.16 TP53 ESR1
6 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly GO:0045899 8.96 TP53 ESR1
7 intracellular steroid hormone receptor signaling pathway GO:0030518 8.62 PGR ESR1

Molecular functions related to Bartholin's Gland Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 9.65 TP53 PGR ESR1
2 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 9.63 TP53 PGR ESR1
3 zinc ion binding GO:0008270 9.61 TP53 PGR ESR1
4 DNA-binding transcription factor activity GO:0003700 9.54 TP53 PGR ESR1
5 DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 9.43 TP53 PGR ESR1
6 ATPase binding GO:0051117 9.4 PGR ESR1
7 nuclear receptor activity GO:0004879 9.32 PGR ESR1
8 steroid binding GO:0005496 9.16 PGR ESR1
9 enzyme binding GO:0019899 9.13 TP53 PGR ESR1
10 steroid hormone receptor activity GO:0003707 8.62 PGR ESR1

Sources for Bartholin's Gland Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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