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MCID: BRT045
MIFTS: 28

Bartholin's Gland Benign Neoplasm

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Bartholin's Gland Benign Neoplasm

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MalaCards integrated aliases for Bartholin's Gland Benign Neoplasm:

Name: Bartholin's Gland Benign Neoplasm 12 15
Bartholin Gland Neoplasm 12 71
Bartholin's Gland Carcinoma 71
Tumor of Bartholin's Gland 12

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Reproductive diseases Endocrine diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:2068
NCIt 49 C6434
UMLS 71 C0220616 C0349561
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Summaries for Bartholin's Gland Benign Neoplasm

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MalaCards based summary : Bartholin's Gland Benign Neoplasm, also known as bartholin gland neoplasm, is related to bartholin's gland adenoma and bartholin's gland adenomyoma. An important gene associated with Bartholin's Gland Benign Neoplasm is NHS (NHS Actin Remodeling Regulator), and among its related pathways/superpathways are Gastric cancer and Thyroid hormone signaling pathway. Affiliated tissues include breast, ovary and bone, and related phenotype is no phenotypic analysis.

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Related Diseases for Bartholin's Gland Benign Neoplasm

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Diseases related to Bartholin's Gland Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 150)
# Related Disease Score Top Affiliating Genes
1 bartholin's gland adenoma 30.8 TP53 PGR NHS ESR1
2 bartholin's gland adenomyoma 11.5
3 carcinosarcoma 10.0 TP53 PGR
4 bartholin's gland disease 10.0 PGR NHS
5 apocrine adenosis of breast 10.0 TP53 PGR
6 primary peritoneal carcinoma 10.0 TP53 PGR
7 gastric diffuse adenocarcinoma 10.0 TP53 PGR
8 chordoid glioma 10.0 TP53 PGR
9 vulvar disease 9.9 TP53 PGR
10 papillary serous adenocarcinoma 9.9 TP53 PGR
11 pleomorphic carcinoma 9.9 TP53 PGR
12 ovarian clear cell adenocarcinoma 9.9 TP53 PGR
13 oropharynx cancer 9.9 TP53 PGR
14 cervical adenocarcinoma 9.9 TP53 ESR1
15 papillary adenocarcinoma 9.9 TP53 PGR
16 papilloma 9.9 TP53 ESR1
17 wolffian duct adenocarcinoma 9.8 TP53 ESR1
18 endometrial clear cell adenocarcinoma 9.8 TP53 ESR1
19 leiomyoma 9.8 PGR ESR1
20 myoma 9.8 PGR ESR1
21 adenosquamous carcinoma 9.8 TP53 PGR
22 serous cystadenocarcinoma 9.8 TP53 PGR
23 glassy cell carcinoma of the cervix 9.8 PGR ESR1
24 bartholin's gland adenoid cystic carcinoma 9.8 PGR ESR1
25 chronic tympanitis 9.8 PGR ESR1
26 granulomatous endometritis 9.8 PGR ESR1
27 endometritis 9.8 PGR ESR1
28 cystadenocarcinoma 9.8 TP53 PGR
29 breast juvenile papillomatosis 9.8 PGR ESR1
30 lung leiomyoma 9.8 PGR ESR1
31 vulvar syringoma 9.8 PGR ESR1
32 trigonitis 9.8 PGR ESR1
33 breast scirrhous carcinoma 9.8 PGR ESR1
34 oncocytic breast carcinoma 9.8 PGR ESR1
35 vagina leiomyosarcoma 9.8 PGR ESR1
36 adult type testicular granulosa cell tumor 9.8 PGR ESR1
37 breast papillary carcinoma 9.8 PGR ESR1
38 papillary carcinoma 9.8 PGR ESR1
39 breast leiomyoma 9.8 PGR ESR1
40 intravenous leiomyomatosis 9.8 PGR ESR1
41 leiomyomatosis 9.8 PGR ESR1
42 liver leiomyoma 9.8 PGR ESR1
43 breast metaplastic carcinoma 9.8 PGR ESR1
44 mammographic density 9.8 PGR ESR1
45 vulvar leiomyoma 9.8 PGR ESR1
46 lipid-rich carcinoma 9.8 PGR ESR1
47 vaginal endometrial stromal sarcoma 9.8 PGR ESR1
48 vagina sarcoma 9.8 PGR ESR1
49 progesterone-receptor negative breast cancer 9.8 PGR ESR1
50 progesterone resistance 9.8 PGR ESR1

Graphical network of the top 20 diseases related to Bartholin's Gland Benign Neoplasm:



Diseases related to Bartholin's Gland Benign Neoplasm
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Symptoms & Phenotypes for Bartholin's Gland Benign Neoplasm

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MGI Mouse Phenotypes related to Bartholin's Gland Benign Neoplasm:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 no phenotypic analysis MP:0003012 8.92 ESR1 NHS PGR TP53
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Drugs & Therapeutics for Bartholin's Gland Benign Neoplasm

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Search Clinical Trials , NIH Clinical Center for Bartholin's Gland Benign Neoplasm

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Genetic Tests for Bartholin's Gland Benign Neoplasm

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Anatomical Context for Bartholin's Gland Benign Neoplasm

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MalaCards organs/tissues related to Bartholin's Gland Benign Neoplasm:

40
Breast, Ovary, Bone, Smooth Muscle, Liver, Lung, Prostate
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Publications for Bartholin's Gland Benign Neoplasm

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Articles related to Bartholin's Gland Benign Neoplasm:

(show all 21)
# Title Authors PMID Year
1
29-year-old with dyspareunia and vulvar mass: An unusual diagnosis of Bartholin's gland carcinoma. 61
30555885 2019
2
Adenoid Cystic Carcinoma of Bartholin's Gland: Case Report. 61
28120596 2016
3
[Bartholin's gland carcinoma]. 61
24951185 2014
4
Management of Bartholin's gland carcinoma using high-dose-rate interstitial brachytherapy boost. 61
23406985 2013
5
Bartholin's gland carcinoma: epidemiology and therapeutic management. 61
23499140 2013
6
Bartholin's gland leiomyoma: a diagnostic and management dilemma. 61
22486791 2012
7
Primary treatment of Bartholin's gland carcinoma with radiation and chemoradiation: a report on ten consecutive cases. 61
17504379 2007
8
Bartholin's gland carcinoma from Crohn's disease. 61
17365482 2007
9
The problem of accurate initial diagnosis of Bartholin's gland carcinoma resulting in delayed treatment and aggressive course of the disease. 61
16803552 2006
10
Bartholin's gland carcinoma, malignant melanoma and other rare tumours of the vulva. 61
12965135 2003
11
Stage IV carcinoma of the Bartholin gland managed with primary chemoradiation. 61
12477454 2002
12
Rectus femoris myocutaneous flap for vulvoperineal reconstruction. 61
11925143 2002
13
Bartholin's gland carcinoma: a 15-year experience. 61
11531274 2001
14
Recurrent squamous cell carcinoma of the Bartholin's duct treated with en bloc resection. 61
10525387 1999
15
[Primary Bartholin gland cancer and etiopathogenetic role of human papillomavirus. Report of a new case]. 61
7644870 1995
16
Carcinomas of Bartholin's gland. Histogenesis and the etiological role of human papillomavirus. 61
8384409 1993
17
Bartholin's gland mixed carcinoma predominantly of the transitional cell type following radiotherapy for a cervical carcinoma. 61
2356673 1990
18
Bartholin's gland carcinoma. 61
6934377 1980
19
Discussion of Carl Furr's presentation: Bartholin's gland carcinoma. 61
6934378 1980
20
Adenocarcinoma of Bartholin's gland. 61
6893395 1980
21
Bartholin's gland carcinoma: an ultrastructural study. 61
623175 1978
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Variations for Bartholin's Gland Benign Neoplasm

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Expression for Bartholin's Gland Benign Neoplasm

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Search GEO for disease gene expression data for Bartholin's Gland Benign Neoplasm.
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Pathways for Bartholin's Gland Benign Neoplasm

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Pathways related to Bartholin's Gland Benign Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Gastric cancer 36
Show member pathways
 12.1 TP53 PGR ESR1
2
Thyroid hormone signaling pathway 36
11.48 TP53 ESR1
3
Signaling by ERBB4 65
Show member pathways
 11.4 PGR ESR1
4
Nuclear Receptor transcription pathway 65
Show member pathways
 11.28 PGR ESR1
5
LKB1 signaling events 1
10.78 TP53 ESR1
6
Ovarian tumor domain proteases 65
10.52 TP53 ESR1
7
Signaling mediated by p38-alpha and p38-beta 1
10.17 TP53 ESR1
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GO Terms for Bartholin's Gland Benign Neoplasm

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Biological processes related to Bartholin's Gland Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of gene expression GO:0010629 9.33 TP53 PGR ESR1
2 steroid hormone mediated signaling pathway GO:0043401 9.26 PGR ESR1
3 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly GO:0045899 8.96 TP53 ESR1
4 negative regulation of production of miRNAs involved in gene silencing by miRNA GO:1903799 8.62 TP53 ESR1

Molecular functions related to Bartholin's Gland Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 zinc ion binding GO:0008270 9.61 TP53 PGR ESR1
2 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 9.54 TP53 PGR ESR1
3 ATPase binding GO:0051117 9.4 PGR ESR1
4 DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 9.33 TP53 PGR ESR1
5 steroid hormone receptor activity GO:0003707 9.32 PGR ESR1
6 nuclear receptor activity GO:0004879 9.26 PGR ESR1
7 enzyme binding GO:0019899 9.13 TP53 PGR ESR1
8 steroid binding GO:0005496 8.62 PGR ESR1
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Sources for Bartholin's Gland Benign Neoplasm

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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