Bartholin's Gland Benign Neoplasm disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Bartholin's Gland Benign Neoplasm

MalaCards integrated aliases for Bartholin's Gland Benign Neoplasm:

Name: Bartholin's Gland Benign Neoplasm ¹² ¹⁵

Bartholin Gland Neoplasm ¹² ⁷⁴

Bartholin's Gland Carcinoma ⁷⁴

Tumor of Bartholin's Gland ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Reproductive diseases Endocrine diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:2068

NCIt ⁵¹ C6434

UMLS ⁷⁴ C0220616 C0349561

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Summaries for Bartholin's Gland Benign Neoplasm

MalaCards based summary : Bartholin's Gland Benign Neoplasm, also known as bartholin gland neoplasm, is related to bartholin's gland adenoma and bartholin's gland adenomyoma. An important gene associated with Bartholin's Gland Benign Neoplasm is PGR (Progesterone Receptor), and among its related pathways/superpathways are Gastric cancer and Proteoglycans in cancer. Related phenotypes are limbs/digits/tail and muscle

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Related Diseases for Bartholin's Gland Benign Neoplasm

Diseases related to Bartholin's Gland Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 111)

#	Related Disease	Score	Top Affiliating Genes
1	bartholin's gland adenoma	31.9	ESR1 PGR
2	bartholin's gland adenomyoma	11.4
3	carcinosarcoma	10.1	PGR TP53
4	endometrium carcinoma in situ	10.1	PGR TP53
5	breast malignant phyllodes tumor	10.1	PGR TP53
6	olfactory groove meningioma	10.1	PGR TP53
7	papillary serous adenocarcinoma	10.0	PGR TP53
8	uterine body mixed cancer	10.0	PGR TP53
9	adenoid cystic carcinoma	10.0	PGR TP53
10	bartholin's gland disease	10.0	PGR TP53
11	microglandular adenosis	10.0	PGR TP53
12	anterior cranial fossa meningioma	10.0	PGR TP53
13	mixed cell type cancer	10.0	PGR TP53
14	primary peritoneal carcinoma	10.0	PGR TP53
15	papillary adenocarcinoma	10.0	PGR TP53
16	muscle cancer	10.0	PGR TP53
17	serous cystadenocarcinoma	9.9	PGR TP53
18	cystadenocarcinoma	9.9	PGR TP53
19	ovarian serous cystadenocarcinoma	9.9	PGR TP53
20	vestibular gland benign neoplasm	9.9	ESR1 PGR
21	vulvar syringoma	9.9	ESR1 PGR
22	lung leiomyoma	9.9	ESR1 PGR
23	leiomyoma	9.9	ESR1 PGR
24	myoma	9.9	ESR1 PGR
25	glassy cell carcinoma of the cervix	9.9	ESR1 PGR
26	vulvar benign neoplasm	9.9	ESR1 PGR
27	trigonitis	9.9	ESR1 PGR
28	vulvar leiomyoma	9.9	ESR1 PGR
29	hidradenocarcinoma	9.9	ESR1 TP53
30	predominantly cortical thymoma	9.9	ESR1 PGR
31	breast medullary carcinoma	9.9	ESR1 PGR
32	breast scirrhous carcinoma	9.9	ESR1 PGR
33	oncocytic breast carcinoma	9.9	ESR1 PGR
34	leiomyosarcoma	9.9	PGR TP53
35	progesterone-receptor positive breast cancer	9.9	ESR1 PGR
36	progesterone resistance	9.9	ESR1 PGR
37	endometrial squamous cell carcinoma	9.9	ESR1 PGR
38	cribriform carcinoma	9.9	ESR1 PGR
39	endometrial mucinous adenocarcinoma	9.9	ESR1 PGR
40	adenoid basal cell carcinoma	9.9	ESR1 PGR
41	apocrine adenocarcinoma	9.9	ESR1 PGR
42	peritoneal benign neoplasm	9.9	ESR1 PGR
43	gender identity disorder	9.9	ESR1 PGR
44	deep angioma	9.9	ESR1 PGR
45	diffuse peritoneal leiomyomatosis	9.9	ESR1 PGR
46	leiomyomatosis	9.9	ESR1 PGR
47	breast adenoid cystic carcinoma	9.9	ESR1 PGR
48	estrogen excess	9.9	ESR1 PGR
49	intramuscular hemangioma	9.9	ESR1 PGR
50	mammographic density	9.9	ESR1 PGR

Graphical network of the top 20 diseases related to Bartholin's Gland Benign Neoplasm:

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Symptoms & Phenotypes for Bartholin's Gland Benign Neoplasm

MGI Mouse Phenotypes related to Bartholin's Gland Benign Neoplasm:

⁴⁷

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	limbs/digits/tail	MP:0005371	9.43	ESR1 PGR TP53
2	muscle	MP:0005369	9.33	ESR1 PGR TP53
3	neoplasm	MP:0002006	9.13	ESR1 PGR TP53
4	no phenotypic analysis	MP:0003012	8.8	ESR1 PGR TP53

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Drugs & Therapeutics for Bartholin's Gland Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Bartholin's Gland Benign Neoplasm

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Genetic Tests for Bartholin's Gland Benign Neoplasm

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Anatomical Context for Bartholin's Gland Benign Neoplasm

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Publications for Bartholin's Gland Benign Neoplasm

Articles related to Bartholin's Gland Benign Neoplasm:

(show all 11)

#	Title	Authors	Year
1	29-year-old with dyspareunia and vulvar mass: An unusual diagnosis of Bartholin's gland carcinoma. ( 30555885 )	Billingsley C...Loreen A	2019
2	Bartholin's gland carcinoma: epidemiology and therapeutic management. ( 23499140 )	Ouldamer L....Body G.	2013
3	Management of Bartholin's gland carcinoma using high-dose-rate interstitial brachytherapy boost. ( 23406985 )	Thibault I....Vigneault A.8.	2013
4	Primary treatment of Bartholin's gland carcinoma with radiation and chemoradiation: a report on ten consecutive cases. ( 17504379 )	LA^pez-Varela E....Fuller A.F.	2007
5	Bartholin's gland carcinoma from Crohn's disease. ( 17365482 )	Amu J....Sanusi A.	2007
6	The problem of accurate initial diagnosis of Bartholin's gland carcinoma resulting in delayed treatment and aggressive course of the disease. ( 16803552 )	Wydra D....Milczek T.	2006
7	Bartholin's gland carcinoma, malignant melanoma and other rare tumours of the vulva. ( 12965135 )	Finan M.A....Barre G.	2003
8	Bartholin's gland carcinoma: a 15-year experience. ( 11531274 )	Cardosi R.J....Hoffman M.S.	2001
9	Bartholin's gland carcinoma. ( 6934377 )	Furr C.A.	1980
10	Discussion of Carl Furr's presentation: Bartholin's gland carcinoma. ( 6934378 )	Fowler W.	1980
11	Bartholin's gland carcinoma: an ultrastructural study. ( 623175 )	Advani H....Bigelow B.	1978

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Genes for Bartholin's Gland Benign Neoplasm

Genes related to Bartholin's Gland Benign Neoplasm (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	PGR	Progesterone Receptor	Protein Coding	14.02	DISEASES inferred ¹⁵
2	ESR1	Estrogen Receptor 1	Protein Coding	13.77	DISEASES inferred ¹⁵
3	TP53	Tumor Protein P53	Protein Coding	13.07	DISEASES inferred ¹⁵

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Variations for Bartholin's Gland Benign Neoplasm

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Expression for Bartholin's Gland Benign Neoplasm

Search GEO for disease gene expression data for Bartholin's Gland Benign Neoplasm.

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Pathways for Bartholin's Gland Benign Neoplasm

Pathways related to Bartholin's Gland Benign Neoplasm according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Gastric cancer ³⁸ Show member pathways Breast cancer ³⁸ Hepatocellular carcinoma ³⁸	11.8	ESR1 PGR TP53
2	Proteoglycans in cancer ³⁸	11.78	ESR1 TP53
3	Cell cycle Role of SCF complex in cell cycle regulation ²³ Show member pathways Cell cycle ESR1 regulation of G1/S transition ²³ Cell cycle Regulation of G1/S transition (part 1) ²³ Immune response MIF-JAB1 signaling ²³	11.7	ESR1 PGR
4	Integrated Breast Cancer Pathway ¹	11.62	ESR1 TP53
5	Thyroid hormone signaling pathway ³⁸	11.47	ESR1 TP53
6	Signaling by ERBB4 ⁶⁷ Show member pathways Downregulation of ERBB4 signaling ⁶⁷ ErbB4 signaling events ¹ Nuclear signaling by ERBB4 ⁶⁷	11.4	ESR1 PGR
7	Nuclear Receptor transcription pathway ⁶⁷ Show member pathways Nuclear Receptors ¹	11.28	ESR1 PGR
8	LKB1 signaling events ¹	10.88	ESR1 TP53
9	Ovarian tumor domain proteases ⁶⁷	10.72	ESR1 TP53
10	Signaling mediated by p38-alpha and p38-beta ¹	10.17	ESR1 TP53

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GO Terms for Bartholin's Gland Benign Neoplasm

Cellular components related to Bartholin's Gland Benign Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	nuclear chromatin	GO:0000790	8.62	ESR1 TP53

Biological processes related to Bartholin's Gland Benign Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	regulation of transcription, DNA-templated	GO:0006355	9.54	ESR1 PGR TP53
2	positive regulation of transcription by RNA polymerase II	GO:0045944	9.33	ESR1 PGR TP53
3	transcription initiation from RNA polymerase II promoter	GO:0006367	9.26	ESR1 PGR
4	transcription, DNA-templated	GO:0006351	9.02	ESR1
5	steroid hormone mediated signaling pathway	GO:0043401	8.96	ESR1 PGR
6	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly	GO:0045899	8.62	ESR1 TP53

Molecular functions related to Bartholin's Gland Benign Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	DNA-binding transcription factor activity, RNA polymerase II-specific	GO:0000981	9.65	ESR1 PGR TP53
2	identical protein binding	GO:0042802	9.63	ESR1 PGR TP53
3	DNA-binding transcription factor activity	GO:0003700	9.61	ESR1 PGR TP53
4	zinc ion binding	GO:0008270	9.58	ESR1 PGR TP53
5	ATPase binding	GO:0051117	9.37	ESR1 PGR
6	RNA polymerase II proximal promoter sequence-specific DNA binding	GO:0000978	9.33	ESR1 PGR TP53
7	steroid hormone receptor activity	GO:0003707	9.32	ESR1 PGR
8	nuclear receptor activity	GO:0004879	9.26	ESR1 PGR
9	steroid binding	GO:0005496	8.96	ESR1 PGR
10	enzyme binding	GO:0019899	8.8	ESR1 PGR TP53

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