Bartholin's Gland Benign Neoplasm disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Bartholin's Gland Benign Neoplasm

MalaCards integrated aliases for Bartholin's Gland Benign Neoplasm:

Name: Bartholin's Gland Benign Neoplasm ¹² ¹⁵

Bartholin's Gland Carcinoma ¹² ¹⁵ ⁷³

Bartholin Gland Neoplasm ¹² ⁷³

Carcinoma of Bartholin's Gland ¹²

Tumor of Bartholin's Gland ¹²

Bartholin Gland Carcinoma ¹²

Bartholin's Gland Cancer ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Reproductive diseases Endocrine diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:2068 DOID:3999

NCIt ⁵⁰ C6434 C9055

UMLS ⁷³ C0220616 C0349561

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Summaries for Bartholin's Gland Benign Neoplasm

Disease Ontology : ¹² A vulva carcinoma that has material basis in abnormally proliferating cells derives from epithelial cells and is located in Bartholin's gland.

MalaCards based summary : Bartholin's Gland Benign Neoplasm, also known as bartholin's gland carcinoma, is related to vulvar dystrophy and bizarre leiomyoma. An important gene associated with Bartholin's Gland Benign Neoplasm is PGR (Progesterone Receptor), and among its related pathways/superpathways are Glioma and Gastric cancer. Affiliated tissues include lung, skin and bone, and related phenotypes are Decreased viability and Decreased viability

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Related Diseases for Bartholin's Gland Benign Neoplasm

Diseases related to Bartholin's Gland Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 100)

#	Related Disease	Score	Top Affiliating Genes
1	vulvar dystrophy	10.1	CDKN2A PGR
2	bizarre leiomyoma	10.1	CDKN2A PGR
3	retroperitoneal leiomyosarcoma	10.1	ERBB3 PGR
4	tongue disease	10.1	CDKN2A SLC10A2
5	lymphohistiocytoid mesothelioma	10.0	CD86 CDKN2A
6	skin carcinoma in situ	10.0	CD86 CDKN2A
7	vulval paget's disease	10.0	CD86 CDKN2A
8	vulva adenocarcinoma	10.0	CD86 CDKN2A
9	vestibular gland benign neoplasm	10.0	ESR1 PGR
10	bartholin's gland adenoma	10.0	ESR1 PGR
11	vulvar syringoma	10.0	ESR1 PGR
12	glassy cell carcinoma of the cervix	10.0	ESR1 PGR
13	lung leiomyoma	10.0	ESR1 PGR
14	leiomyoma	10.0	ESR1 PGR
15	myoma	10.0	ESR1 PGR
16	vulvar benign neoplasm	10.0	ESR1 PGR
17	trigonitis	10.0	ESR1 PGR
18	vulvar leiomyoma	10.0	ESR1 PGR
19	predominantly cortical thymoma	10.0	ESR1 PGR
20	breast medullary carcinoma	10.0	ESR1 PGR
21	breast scirrhous carcinoma	10.0	ESR1 PGR
22	oncocytic breast carcinoma	10.0	ESR1 PGR
23	progesterone-receptor positive breast cancer	10.0	ESR1 PGR
24	progesterone resistance	10.0	ESR1 PGR
25	cribriform carcinoma	10.0	ESR1 PGR
26	breast adenoid cystic carcinoma	10.0	ESR1 PGR
27	apocrine adenocarcinoma	10.0	ESR1 PGR
28	peritoneal benign neoplasm	10.0	ESR1 PGR
29	gender identity disorder	10.0	ESR1 PGR
30	deep angioma	10.0	ESR1 PGR
31	diffuse peritoneal leiomyomatosis	10.0	ESR1 PGR
32	leiomyomatosis	10.0	ESR1 PGR
33	synchronous bilateral breast carcinoma	10.0	ESR1 PGR
34	female reproductive endometrioid cancer	10.0	ESR1 PGR
35	cervical carcinosarcoma	10.0	ESR1 PGR
36	estrogen excess	10.0	ESR1 PGR
37	intramuscular hemangioma	10.0	ESR1 PGR
38	uterine carcinosarcoma	10.0	ERBB3 PGR
39	mammographic density	10.0	ESR1 PGR
40	cervical clear cell adenocarcinoma	10.0	ESR1 PGR
41	retinitis pigmentosa 47	10.0	ESR1 PGR
42	inflammatory breast carcinoma	10.0	ESR1 PGR
43	retinitis pigmentosa 20	10.0	ESR1 PGR
44	adenosarcoma	10.0	ESR1 PGR
45	endometriosis	10.0	ESR1 PGR
46	endometriosis of ovary	10.0	ESR1 PGR
47	breast benign neoplasm	10.0	ESR1 PGR
48	thoracic benign neoplasm	10.0	ESR1 PGR
49	uterine corpus cancer	10.0	ESR1 PGR
50	lipid-rich carcinoma	10.0	ESR1 PGR

Graphical network of the top 20 diseases related to Bartholin's Gland Benign Neoplasm:

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Symptoms & Phenotypes for Bartholin's Gland Benign Neoplasm

GenomeRNAi Phenotypes related to Bartholin's Gland Benign Neoplasm according to GeneCards Suite gene sharing:

²⁶

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Decreased viability	GR00106-A-0	9.5	ERBB3
2	Decreased viability	GR00221-A-1	9.5	CDKN2A ESR1
3	Decreased viability	GR00221-A-2	9.5	ERBB3 ESR1
4	Decreased viability	GR00221-A-3	9.5	CDKN2A
5	Decreased viability	GR00221-A-4	9.5	CDKN2A ERBB3 ESR1
6	Decreased viability	GR00301-A	9.5	ERBB3
7	Decreased viability	GR00342-S-2	9.5	ERBB3
8	Decreased viability	GR00342-S-3	9.5	ERBB3
9	Decreased viability	GR00402-S-2	9.5	CDKN2A ERBB3 ESR1

MGI Mouse Phenotypes related to Bartholin's Gland Benign Neoplasm:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	behavior/neurological	MP:0005386	9.8	CD86 CDKN2A ERBB3 ESR1 PGR
2	homeostasis/metabolism	MP:0005376	9.73	CD86 CDKN2A ERBB3 ESR1 PGR SLC10A2
3	endocrine/exocrine gland	MP:0005379	9.72	CD86 CDKN2A ERBB3 ESR1 PGR
4	digestive/alimentary	MP:0005381	9.67	CDKN2A ERBB3 ESR1 SLC10A2
5	immune system	MP:0005387	9.55	CD86 CDKN2A ERBB3 ESR1 PGR
6	muscle	MP:0005369	9.35	CD86 CDKN2A ERBB3 ESR1 PGR
7	neoplasm	MP:0002006	8.92	CDKN2A ERBB3 ESR1 PGR

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Drugs & Therapeutics for Bartholin's Gland Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Bartholin's Gland Benign Neoplasm

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Genetic Tests for Bartholin's Gland Benign Neoplasm

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Anatomical Context for Bartholin's Gland Benign Neoplasm

MalaCards organs/tissues related to Bartholin's Gland Benign Neoplasm:

⁴¹

Lung, Skin, Bone, Breast, Ovary, Prostate, Smooth Muscle

The Foundational Model of Anatomy Ontology organs/tissues related to Bartholin's Gland Benign Neoplasm:

¹⁹

Bartholin'S Gl

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Publications for Bartholin's Gland Benign Neoplasm

Articles related to Bartholin's Gland Benign Neoplasm:

(show all 11)

#	Title	Authors	Year
1	29-year-old with dyspareunia and vulvar mass: An unusual diagnosis of Bartholin's gland carcinoma. ( 30555885 )	Billingsley C...Loreen A	2019
2	Bartholin's gland carcinoma: epidemiology and therapeutic management. ( 23499140 )	Ouldamer L....Body G.	2013
3	Management of Bartholin's gland carcinoma using high-dose-rate interstitial brachytherapy boost. ( 23406985 )		2013
4	Primary treatment of Bartholin's gland carcinoma with radiation and chemoradiation: a report on ten consecutive cases. ( 17504379 )	LA^pez-Varela E....Fuller A.F.	2007
5	Bartholin's gland carcinoma from Crohn's disease. ( 17365482 )	Amu J....Sanusi A.	2007
6	The problem of accurate initial diagnosis of Bartholin's gland carcinoma resulting in delayed treatment and aggressive course of the disease. ( 16803552 )	Wydra D....Milczek T.	2006
7	Bartholin's gland carcinoma, malignant melanoma and other rare tumours of the vulva. ( 12965135 )		2003
8	Bartholin's gland carcinoma: a 15-year experience. ( 11531274 )	Cardosi R.J....Hoffman M.S.	2001
9	Bartholin's gland carcinoma. ( 6934377 )	Furr C.A.	1980
10	Discussion of Carl Furr's presentation: Bartholin's gland carcinoma. ( 6934378 )		1980
11	Bartholin's gland carcinoma: an ultrastructural study. ( 623175 )		1978

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Genes for Bartholin's Gland Benign Neoplasm

Genes related to Bartholin's Gland Benign Neoplasm (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	PGR	Progesterone Receptor	Protein Coding	17.71	DISEASES inferred ¹⁵ ¹⁵
2	SLC10A2	Solute Carrier Family 10 Member 2	Protein Coding	16	DISEASES inferred ¹⁵
3	ERBB3	Erb-B2 Receptor Tyrosine Kinase 3	Protein Coding	14.65	DISEASES inferred ¹⁵
4	CD86	CD86 Molecule	Protein Coding	14.29	DISEASES inferred ¹⁵
5	ESR1	Estrogen Receptor 1	Protein Coding	13.8	DISEASES inferred ¹⁵
6	CDKN2A	Cyclin Dependent Kinase Inhibitor 2A	Protein Coding	13.67	DISEASES inferred ¹⁵

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Variations for Bartholin's Gland Benign Neoplasm

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Expression for Bartholin's Gland Benign Neoplasm

Search GEO for disease gene expression data for Bartholin's Gland Benign Neoplasm.

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Pathways for Bartholin's Gland Benign Neoplasm

Pathways related to Bartholin's Gland Benign Neoplasm according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Glioma ³⁷ Show member pathways EGFR tyrosine kinase inhibitor resistance ³⁷ Endocrine resistance ³⁷ Melanoma ³⁷ Non-small cell lung cancer ³⁷ Signaling Pathways in Glioblastoma ¹	12.1	CDKN2A ERBB3 ESR1
2	Gastric cancer ³⁷ Show member pathways Breast cancer ³⁷ Hepatocellular carcinoma ³⁷	12	CDKN2A ESR1 PGR
3	Cell cycle Role of SCF complex in cell cycle regulation ²² Show member pathways Cell cycle ESR1 regulation of G1/S transition ²² Cell cycle Regulation of G1/S transition (part 1) ²² Immune response MIF-JAB1 signaling ²²	11.38	CDKN2A ESR1 PGR
4	Nuclear Receptor transcription pathway ⁶⁶ Show member pathways Nuclear Receptors ¹	11.28	ESR1 PGR
5	Signaling by ERBB4 ⁶⁶ Show member pathways Downregulation of ERBB4 signaling ⁶⁶ ErbB4 signaling events ¹ Nuclear signaling by ERBB4 ⁶⁶	10.83	ERBB3 ESR1 PGR

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GO Terms for Bartholin's Gland Benign Neoplasm

Biological processes related to Bartholin's Gland Benign Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	steroid hormone mediated signaling pathway	GO:0043401	9.16	ESR1 PGR
2	positive regulation of protein kinase B signaling	GO:0051897	9.13	CD86 ERBB3 ESR1
3	phosphatidylinositol phosphorylation	GO:0046854	8.8	CD86 ERBB3 ESR1

Molecular functions related to Bartholin's Gland Benign Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	ATPase binding	GO:0051117	9.32	ESR1 PGR
2	steroid hormone receptor activity	GO:0003707	9.26	ESR1 PGR
3	nuclear receptor activity	GO:0004879	9.16	ESR1 PGR
4	steroid binding	GO:0005496	8.96	ESR1 PGR
5	phosphatidylinositol-4,5-bisphosphate 3-kinase activity	GO:0046934	8.8	CD86 ERBB3 ESR1

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