MCID: BRT060
MIFTS: 29

Bartholin's Gland Disease

Categories: Endocrine diseases, Reproductive diseases

Aliases & Classifications for Bartholin's Gland Disease

MalaCards integrated aliases for Bartholin's Gland Disease:

Name: Bartholin's Gland Disease 12 15
Bartholin Gland Disease 17

Classifications:



External Ids:

Disease Ontology 12 DOID:60002
ICD10 34 N75

Summaries for Bartholin's Gland Disease

Disease Ontology : 12 Disease that is located in Bartholin's gland.

MalaCards based summary : Bartholin's Gland Disease, also known as bartholin gland disease, is related to uterine body mixed cancer and anterior cranial fossa meningioma. An important gene associated with Bartholin's Gland Disease is SLC10A2 (Solute Carrier Family 10 Member 2), and among its related pathways/superpathways are Signaling by ERBB4 and Inhibition of Ribosome Biogenesis by p14(ARF). Related phenotypes are Decreased viability in esophageal squamous lineage and cellular

Wikipedia : 77 The Bartholin''s glands (also called Bartholin glands or greater vestibular glands) are two pea sized... more...

Related Diseases for Bartholin's Gland Disease

Diseases related to Bartholin's Gland Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 225)
# Related Disease Score Top Affiliating Genes
1 uterine body mixed cancer 10.5 PGR TP53
2 anterior cranial fossa meningioma 10.5 PGR TP53
3 olfactory groove meningioma 10.4 PGR TP53
4 sclerosing liposarcoma 10.4 PAX8 TP53
5 retroperitoneal leiomyosarcoma 10.4 ERBB3 PGR
6 sarcomatoid mesothelioma 10.4 CDKN2A NAPSA
7 thyroid lymphoma 10.4 CDKN2A TP53
8 anogenital venereal wart 10.4 CDKN2A TP53
9 megaesophagus 10.4 CDKN2A TP53
10 vulva squamous cell carcinoma 10.4 CDKN2A TP53
11 scrotal carcinoma 10.4 CDKN2A TP53
12 anal squamous cell carcinoma 10.4 CDKN2A TP53
13 gastric adenosquamous carcinoma 10.4 CDKN2A TP53
14 cervix uteri carcinoma in situ 10.4 CDKN2A TP53
15 uterus carcinoma in situ 10.4 CDKN2A TP53
16 oral leukoplakia 10.4 CDKN2A TP53
17 spitz nevus 10.4 CDKN2A TP53
18 progesterone resistance 10.4 ESR1 PGR
19 mammographic density 10.4 ESR1 PGR
20 retinitis pigmentosa 47 10.4 ESR1 PGR
21 progesterone-receptor positive breast cancer 10.4 ESR1 PGR
22 gender identity disorder 10.4 ESR1 PGR
23 estrogen excess 10.4 ESR1 PGR
24 intramuscular hemangioma 10.4 ESR1 PGR
25 deep angioma 10.4 ESR1 PGR
26 breast adenoid cystic carcinoma 10.4 ESR1 PGR
27 apocrine adenocarcinoma 10.4 ESR1 PGR
28 cervical clear cell adenocarcinoma 10.4 ESR1 PGR
29 inflammatory breast carcinoma 10.4 ESR1 PGR
30 endometrium carcinoma in situ 10.4 PGR TP53
31 breast squamous cell carcinoma 10.3 CD86 TP53
32 breast giant fibroadenoma 10.3 CDKN2A ESR1
33 papillary adenoma 10.3 KRT7 NAPSA
34 thymus adenocarcinoma 10.3 KRT7 NAPSA
35 corneal abscess 10.3 KRT7 PGR
36 pancreatic serous cystadenoma 10.3 KRT7 PGR
37 vestibular gland benign neoplasm 10.3 ESR1 PGR
38 bartholin's gland adenoma 10.3 ESR1 PGR
39 benign metastasizing leiomyoma 10.3 KRT7 PGR
40 renal pelvis carcinoma 10.3 KRT7 PAX8
41 vulvar syringoma 10.3 ESR1 PGR
42 prostate squamous cell carcinoma 10.3 KRT7 TP53
43 skin carcinoma in situ 10.3 CD86 CDKN2A
44 lung leiomyoma 10.3 ESR1 PGR
45 vulvar dystrophy 10.3 CDKN2A PGR
46 glassy cell carcinoma of the cervix 10.3 ESR1 PGR
47 anal canal carcinoma 10.3 CDKN2A KRT7
48 vulvar benign neoplasm 10.3 ESR1 PGR
49 nasal cavity cancer 10.3 CDKN2A KRT7
50 trigonitis 10.3 ESR1 PGR

Graphical network of the top 20 diseases related to Bartholin's Gland Disease:



Diseases related to Bartholin's Gland Disease

Symptoms & Phenotypes for Bartholin's Gland Disease

GenomeRNAi Phenotypes related to Bartholin's Gland Disease according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability in esophageal squamous lineage GR00235-A 9.23 CALB2 CD86 CDKN2A ESR1 KRT7 PAX8

MGI Mouse Phenotypes related to Bartholin's Gland Disease:

47 (show all 12)
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.19 CD86 CDKN2A ERBB3 ESR1 GATA3 KRT7
2 homeostasis/metabolism MP:0005376 10.14 CD86 CDKN2A ERBB3 ESR1 GATA3 KRT7
3 cardiovascular system MP:0005385 10.11 CDKN2A ERBB3 ESR1 GATA3 PAX8 PGR
4 endocrine/exocrine gland MP:0005379 10.09 CD86 CDKN2A ERBB3 ESR1 GATA3 PAX8
5 digestive/alimentary MP:0005381 10.02 CDKN2A ERBB3 ESR1 GATA3 PIP SLC10A2
6 immune system MP:0005387 10.02 CD86 CDKN2A ERBB3 ESR1 GATA3 MME
7 embryo MP:0005380 10 CDKN2A ERBB3 ESR1 GATA3 PAX8 PGR
8 integument MP:0010771 9.87 CDKN2A ERBB3 ESR1 GATA3 MME PGR
9 muscle MP:0005369 9.8 CD86 CDKN2A ERBB3 ESR1 GATA3 PGR
10 no phenotypic analysis MP:0003012 9.63 CDKN2A ESR1 GATA3 PAX8 PGR TP53
11 normal MP:0002873 9.5 CALB2 ERBB3 ESR1 GATA3 PAX8 PGR
12 reproductive system MP:0005389 9.17 CDKN2A ESR1 GATA3 PAX8 PGR PIP

Drugs & Therapeutics for Bartholin's Gland Disease

Search Clinical Trials , NIH Clinical Center for Bartholin's Gland Disease

Genetic Tests for Bartholin's Gland Disease

Anatomical Context for Bartholin's Gland Disease

Publications for Bartholin's Gland Disease

Variations for Bartholin's Gland Disease

Expression for Bartholin's Gland Disease

Search GEO for disease gene expression data for Bartholin's Gland Disease.

Pathways for Bartholin's Gland Disease

Pathways related to Bartholin's Gland Disease according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.83 ERBB3 ESR1 PGR
2 10.5 CDKN2A TP53
3
Show member pathways
10.3 CDKN2A TP53

GO Terms for Bartholin's Gland Disease

Biological processes related to Bartholin's Gland Disease according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription by RNA polymerase II GO:0045944 9.88 CDKN2A ESR1 GATA3 PAX8 PGR TP53
2 positive regulation of gene expression GO:0010628 9.72 CDKN2A ERBB3 GATA3 PIP TP53
3 kidney development GO:0001822 9.67 GATA3 MME PAX8
4 phosphatidylinositol phosphorylation GO:0046854 9.65 CD86 ERBB3 ESR1
5 positive regulation of protein kinase B signaling GO:0051897 9.56 CD86 ERBB3 ESR1 GATA3
6 uterus development GO:0060065 9.51 ESR1 GATA3
7 mesonephros development GO:0001823 9.46 GATA3 PAX8
8 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly GO:0045899 9.43 ESR1 TP53
9 positive regulation of transcription, DNA-templated GO:0045893 9.43 CD86 CDKN2A ESR1 GATA3 PAX8 TP53
10 otic vesicle development GO:0071599 9.37 GATA3 PAX8
11 positive regulation of thyroid hormone generation GO:2000611 9.16 GATA3 PAX8
12 replicative senescence GO:0090399 8.8 CDKN2A MME TP53

Molecular functions related to Bartholin's Gland Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 zinc ion binding GO:0008270 9.65 ESR1 GATA3 MME PGR TP53
2 transcription factor binding GO:0008134 9.46 CDKN2A ESR1 GATA3 TP53
3 aspartic-type endopeptidase activity GO:0004190 9.32 NAPSA PIP
4 phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 9.13 CD86 ERBB3 ESR1
5 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 9.02 ESR1 GATA3 PAX8 PGR TP53

Sources for Bartholin's Gland Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....