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MCID: BRT043
MIFTS: 37

Bartonellosis

Categories: Infectious diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Bartonellosis

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MalaCards integrated aliases for Bartonellosis:

Name: Bartonellosis 12 15
Bartonella Infections 44 73
Bartonella Infectious Disease 12
Rochalimaea Infection 12
Bartonelliasis 12

Classifications:

MalaCards categories:
Global: Infectious diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:11102
ICD10 33 A44 A44.9
ICD9CM 35 088.0
MeSH 44 D001474
NCIt 50 C84586
UMLS 73 C0004771
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Summaries for Bartonellosis

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Disease Ontology : 12 A primary bacterial infectious disease that is caused by the bacteria of the genus Bartonella.

MalaCards based summary : Bartonellosis, also known as bartonella infections, is related to cat-scratch disease and carrion's disease. An important gene associated with Bartonellosis is CD40LG (CD40 Ligand), and among its related pathways/superpathways is Mitochondrial protein import. The drugs Azithromycin and Prednisone have been mentioned in the context of this disorder. Affiliated tissues include liver, kidney and bone, and related phenotype is Decreased viability with cisplatin.

Wikipedia : 76 Bartonellosis is an infectious disease produced by bacteria of the genus Bartonella.Bartonella species... more...

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Related Diseases for Bartonellosis

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Diseases related to Bartonellosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 34)
# Related Disease Score Top Affiliating Genes
1 cat-scratch disease 31.2 CD40LG CS EEA1 HSPD1 HTRA1
2 carrion's disease 31.1 ASXL3 CD40LG HSPD1 HSPE1
3 bacillary angiomatosis 30.7 ATR HSPE1 STAB1
4 ehrlichiosis 30.5 CD40LG HSPD1
5 neuroretinitis 30.3 CD40LG CS
6 trench fever 11.2
7 fallopian tube disease 10.5 CD40LG HSPD1
8 post-vaccinal encephalitis 10.5 CD40LG HTRA1
9 salpingitis 10.5 CD40LG HSPD1
10 urethritis 10.5 CD40LG HSPD1
11 human granulocytic anaplasmosis 10.4 CD40LG HSPD1
12 endocardium disease 10.4 CD40LG HSPD1
13 pelvic inflammatory disease 10.3 CD40LG HSPD1
14 mixed connective tissue disease 10.2 CD40LG HSPD1
15 cutaneous lupus erythematosus 10.2 CD40LG EEA1
16 lyme disease 10.1 CD40LG HSPD1
17 primary bacterial infectious disease 10.0 CD40LG HSPD1
18 babesiosis 10.0
19 sennetsu fever 9.9 HSPD1 HSPE1
20 angiomatosis 9.9
21 chancroid 9.9 HSPD1 HSPE1
22 leukodystrophy, hypomyelinating, 4 9.9 HSPD1 HSPE1
23 chlamydia 9.8 CD40LG HSPD1
24 chronic kidney failure 9.8
25 thrombocytopenia 9.8
26 uveitis 9.8
27 hyperinsulinemic hypoglycemia 9.8
28 plague 9.8
29 kidney disease 9.8
30 macular holes 9.8
31 iridocyclitis 9.8
32 yellow fever 9.8
33 hypoglycemia 9.8
34 leprosy 3 9.6 CD40LG HSPD1 HSPE1

Graphical network of the top 20 diseases related to Bartonellosis:



Diseases related to Bartonellosis
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Symptoms & Phenotypes for Bartonellosis

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GenomeRNAi Phenotypes related to Bartonellosis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability with cisplatin GR00101-A-4 8.62 ASXL3 ATR
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Drugs & Therapeutics for Bartonellosis

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Drugs for Bartonellosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 40)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Azithromycin Approved Phase 4,Phase 3 83905-01-5 55185 447043
2
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
3
Emtricitabine Approved, Investigational Phase 4 143491-57-0 60877
4
Nevirapine Approved Phase 4 129618-40-2 4463
5
Ritonavir Approved, Investigational Phase 4,Phase 3 155213-67-5 392622
6 Anti-Inflammatory Agents Phase 4
7 Antineoplastic Agents, Hormonal Phase 4
8 glucocorticoids Phase 4
9 Hormone Antagonists Phase 4
10 Hormones Phase 4
11 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
12 Anti-HIV Agents Phase 4,Phase 3
13 Anti-Infective Agents Phase 4,Phase 3
14 Anti-Retroviral Agents Phase 4,Phase 3
15 Antiviral Agents Phase 4,Phase 3
16 Atazanavir Sulfate Phase 4
17 Cytochrome P-450 CYP3A Inducers Phase 4
18 Cytochrome P-450 CYP3A Inhibitors Phase 4
19 Cytochrome P-450 Enzyme Inhibitors Phase 4
20 Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination Phase 4
21 HIV Protease Inhibitors Phase 4,Phase 3
22 Nucleic Acid Synthesis Inhibitors Phase 4
23
protease inhibitors Phase 4,Phase 3
24 Reverse Transcriptase Inhibitors Phase 4
25
Tenofovir Phase 4 147127-20-6 464205
26
Aldesleukin Approved Phase 3 85898-30-2, 110942-02-4
27
Benzocaine Approved, Investigational Phase 3 1994-09-7, 94-09-7 2337
28
Efavirenz Approved, Investigational Phase 3 154598-52-4 64139
29
Fosamprenavir Approved Phase 3 226700-79-4 131536
30
Maraviroc Approved, Investigational Phase 3 376348-65-1 3002977
31 tannic acid Approved, Nutraceutical Phase 3
32 Analgesics Phase 3
33 Analgesics, Non-Narcotic Phase 3
34 Interleukin-2 Phase 3
35 Peripheral Nervous System Agents Phase 3
36 Anti-Bacterial Agents Phase 3
37 Gentamicins Phase 3
38 Antibodies
39 Immunoglobulins
40 Liver Extracts

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Efficacy of Prednisone and Azithromycin in the Treatment of Patients With Cat Scratch Disease Unknown status NCT01469702 Phase 4 prednison and azithromycin;prednison, azithromycin;prednison, Azenil
2 Nevirapine vs. Atazanavir Boosted With Ritonavir on a Background of Truvada in Human Immunodeficiency Virus (HIV) Infected Naive Patients (NEwArT) Completed NCT00552240 Phase 4 tenofovir DF 300 mg QD;tenofovir DF 300 mg QD;emtricitabine 200 mg QD;emtricitabine 200 mg QD;Nevirapine 200 mg BID;Atazanavir 300 mg;Ritonavir 100 mg
3 Interleukin-2 Plus Antiretroviral Therapy for HIV-Infected Patients With Low CD4+ Counts (SILCAAT Study) Completed NCT00013611 Phase 3 Proleukin
4 An International Study to Evaluate Recombinant Interleukin-2 in HIV Positive Patients Taking Anti-retroviral Therapy Completed NCT00004978 Phase 3 Recombinant interleukin-2 (rIL-2)
5 Immuno-stimulation With Maraviroc Combined to Antiretroviral Therapy in Advanced Late Diagnosed HIV-1 Infected Patients Completed NCT01348308 Phase 3 Maraviroc (Celsentri);Placebo
6 Intra-nodal Injection of Gentamicin for the Treatment of Suppurated Cat Scratch Disease's Lymphadenitis Recruiting NCT03132116 Phase 3 gentamicin;placebo
7 Bartonella in Liver Transplant Patients Recruiting NCT02595710

Search NIH Clinical Center for Bartonellosis

Cochrane evidence based reviews: bartonella infections

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Genetic Tests for Bartonellosis

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Anatomical Context for Bartonellosis

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MalaCards organs/tissues related to Bartonellosis:

41
Liver, Kidney, Bone, Bone Marrow
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Publications for Bartonellosis

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Articles related to Bartonellosis:

(show top 50) (show all 56)
# Title Authors Year
1
Bartonellosis, One Health and all creatures great and small. ( 28133871 )
2017
2
Ocular Bartonellosis. ( 28778273 )
2017
3
Clinical Profile and Visual Outcome of Ocular Bartonellosis in Malaysia. ( 28265290 )
2017
4
Bartonellosis in Chronic Kidney Disease: An Unrecognized and Unsuspected Diagnosis. ( 28884961 )
2017
5
Bartonellosis ( 28613624 )
2017
6
Acute Unilateral Vision Loss in a Female Adolescent Due to Ocular Bartonellosis. ( 28398939 )
2017
7
Ultrasound imaging as the basis of a clinical diagnosis of systemic bartonellosis in a patient after bone marrow transplantation. A case report. ( 27446604 )
2016
8
Role of Whole-Body MR with DWIBS in child's Bartonellosis. ( 27598022 )
2016
9
Clinical determinants of Lyme borreliosis, babesiosis, bartonellosis, anaplasmosis, and ehrlichiosis in an Australian cohort. ( 25565883 )
2015
10
Neuroretinitis in ocular bartonellosis. ( 25453244 )
2015
11
Ocular bartonellosis in transplant recipients: two case reports and review of the literature. ( 26146758 )
2015
12
Hyperinsulinemic hypoglycemia syndrome in 2 dogs with bartonellosis. ( 24934703 )
2014
13
Neuroretinitis in ocular bartonellosis: a case series. ( 25120352 )
2014
14
Risk factors for human lice and bartonellosis among the homeless, San Francisco, California, USA. ( 25280380 )
2014
15
Bartonellosis: one health perspectives for an emerging infectious disease. ( 24936029 )
2014
16
Macular hole: a rare complication of ocular bartonellosis. ( 23681239 )
2013
17
Cat-scratch disease in Northern Italy: atypical clinical manifestations in humans and prevalence of Bartonella infection in cats. ( 23132688 )
2013
18
Cat scratch disease and other Bartonella infections. ( 23654065 )
2013
19
Treatment outcomes of human bartonellosis: a systematic review and meta-analysis. ( 23602630 )
2013
20
Chronic Bartonellosis in cats: what are the potential implications? ( 22918844 )
2012
21
Feline bartonellosis: we're just scratching the surface. ( 22918842 )
2012
22
Beyond cat scratch disease: a case report of bartonella infection mimicking vasculitic disorder. ( 22924138 )
2012
23
Paradoxical response in ocular bartonellosis. ( 22057809 )
2012
24
Cryptogenic hepatitis and bartonellosis. ( 22307338 )
2012
25
Bartonella infective endocarditis of a prosthetic aortic valve with a subvalvular abscess. ( 21848606 )
2011
26
Emerging incidence of Lyme borreliosis, babesiosis, bartonellosis, and granulocytic ehrlichiosis in Australia. ( 22267937 )
2011
27
Bartonellosis in cats: a role in uveitis? ( 21923819 )
2011
28
Disseminated bartonellosis presenting as neuroretinitis in a young adult with human immunodeficiency virus infection. ( 20216243 )
2010
29
Bartonellosis: an emerging infectious disease of zoonotic importance to animals and human beings. ( 20230432 )
2010
30
Bartonellosis diagnosis requires careful evaluation. ( 20835501 )
2010
31
Feline bartonellosis. ( 20933137 )
2010
32
Flea-associated zoonotic diseases of cats in the USA: bartonellosis, flea-borne rickettsioses, and plague. ( 20185369 )
2010
33
Bartonellosis causing bilateral Leber neuroretinitis: a case report. ( 19253255 )
2009
34
Feline bartonellosis and cat scratch disease. ( 18295347 )
2008
35
Alpha1-proteinase inhibitor deficiency and Bartonella infection in association with panniculitis, polyarthritis, and meningitis in a dog. ( 16955834 )
2006
36
Is pyogenic granuloma associated with Bartonella infection? ( 16310070 )
2005
37
Cat-scratch disease (ocular bartonellosis) presenting as bilateral recurrent iridocyclitis. ( 15714406 )
2005
38
Killed in action: microbiologists and clinicians as victims of their occupation. Part 2: Yellow fever and bartonellosis. ( 16128394 )
2005
39
Carrion's disease (Bartonellosis bacilliformis) confirmed by histopathology in the High Forest of Peru. ( 15286824 )
2004
40
Cat scratch disease and other zoonotic Bartonella infections. ( 15112775 )
2004
41
Concurrent bartonellosis and babesiosis in a dog with persistent thrombocytopenia. ( 14621218 )
2003
42
Laboratory diagnosis of Bartonella infections. ( 12489289 )
2002
43
Rheumatic manifestations of Bartonella infection in 2 children. ( 11824958 )
2002
44
Bartonellosis (CarriA^n's disease) in the modern era. ( 11512081 )
2001
45
Granuloma annulare: another manifestation of Bartonella infection? ( 11801791 )
2001
46
Bartonella infection associated with systemic juvenile rheumatoid arthritis. ( 11112671 )
2001
47
Cat scratch disease (bartonellosis) mimicking an SLE flare. ( 11787880 )
2001
48
Disseminated Bartonella infection with granulomatous hepatitis in a liver transplant recipient. ( 10226118 )
1999
49
The expanding spectrum of Bartonella infections: I. Bartonellosis and trench fever. ( 9002093 )
1997
50
Molecular epidemiology of bartonella infections in patients with bacillary angiomatosis-peliosis. ( 9407154 )
1997
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Variations for Bartonellosis

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Expression for Bartonellosis

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Search GEO for disease gene expression data for Bartonellosis.
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Pathways for Bartonellosis

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Pathways related to Bartonellosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Mitochondrial protein import 66
10.42 CS HSPD1
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GO Terms for Bartonellosis

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Cellular components related to Bartonellosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitochondrial matrix GO:0005759 8.8 CS HSPD1 HSPE1

Biological processes related to Bartonellosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 9.32 HSPD1 HSPE1
2 response to unfolded protein GO:0006986 9.26 HSPD1 HSPE1
3 B cell proliferation GO:0042100 9.16 CD40LG HSPD1
4 positive regulation of interleukin-12 production GO:0032735 8.96 CD40LG HSPD1
5 positive regulation of interleukin-10 production GO:0032733 8.62 CD40LG HSPD1
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Sources for Bartonellosis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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