MCID: BRT043
MIFTS: 35

Bartonellosis

Categories: Infectious diseases

Aliases & Classifications for Bartonellosis

MalaCards integrated aliases for Bartonellosis:

Name: Bartonellosis 12 15 17 32
Bartonella Infections 44 70
Bartonella Infectious Disease 12
Rochalimaea Infection 12
Bartonelliasis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11102
ICD9CM 34 088.0
MeSH 44 D001474
NCIt 50 C84586
SNOMED-CT 67 17116008
ICD10 32 A44 A44.9
UMLS 70 C0004771

Summaries for Bartonellosis

Disease Ontology : 12 A primary bacterial infectious disease that is caused by the bacteria of the genus Bartonella.

MalaCards based summary : Bartonellosis, also known as bartonella infections, is related to carrion's disease and trench fever. An important gene associated with Bartonellosis is HSPD1 (Heat Shock Protein Family D (Hsp60) Member 1), and among its related pathways/superpathways is Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Azithromycin and Prednisone have been mentioned in the context of this disorder. Affiliated tissues include skin, bone and breast.

Wikipedia : 73 Bartonellosis is an infectious disease produced by bacteria of the genus Bartonella. Bartonella species... more...

Related Diseases for Bartonellosis

Diseases related to Bartonellosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 398)
# Related Disease Score Top Affiliating Genes
1 carrion's disease 32.4 PPP1R14A HSPD1 CS
2 trench fever 31.1 SYNJ2BP MT-CYB HSPD1 COX18
3 endocarditis 30.6 HTRA1 HSPD1 CRP
4 cat-scratch disease 30.6 TNFRSF8 PPP1R14A HTRA1 HSPD1 EXOSC5 CS
5 neuroretinitis 30.5 CS CRP CD4 ACE
6 babesiosis 30.3 MT-CYB MT-CO1 CD4
7 spotted fever 30.3 PPP1R14A HTRA1 CS
8 chlamydia 30.2 HTRA1 HSPD1 CRP
9 disease by infectious agent 30.2 TNFRSF8 HSPD1 CRP CD4
10 branch retinal artery occlusion 29.9 VEGFA CRP
11 acquired immunodeficiency syndrome 29.8 PECAM1 CRP CD4 CD34
12 optic papillitis 29.8 CRP CD4 ACE
13 choroiditis 29.8 VEGFA HTRA1 CD4 ACE
14 panuveitis 29.7 CRP CD4 ACE
15 immune deficiency disease 29.7 TNFRSF8 HSPD1 CRP CD4 CD34
16 retinal artery occlusion 29.6 VEGFA CRP ACE
17 deficiency anemia 29.6 MT-CYB CRP CD4 CD34 ACE
18 chorioretinitis 29.5 VEGFA CRP CD4 ACE
19 iridocyclitis 29.5 VEGFA CRP CD4 ACE
20 papilledema 29.5 VEGFA CRP CD4 ACE
21 exanthem 29.5 VEGFA CRP CD4 ACE
22 optic nerve disease 29.4 VEGFA MT-CYB MT-CO1 CRP CD4
23 bacillary angiomatosis 29.3 VEGFA SYNJ2BP PPP1R14A PECAM1 MT-CYB HTRA1
24 urticaria 29.0 CRP CD4 ACE
25 pericardial effusion 28.6 VEGFA TNFRSF8 CRP CD68 CD4 CD34
26 epidemic typhus 28.5 PPP1R14A MT-CYB MT-CO1 HTRA1 HSPD1 CS
27 autoimmune atherosclerosis 10.4 HSPD1 CD4
28 inclusion conjunctivitis 10.4 HTRA1 HSPD1
29 riedel's fibrosing thyroiditis 10.4 CD4 CD34
30 panophthalmitis 10.4 CRP CD4
31 cyclosporiasis 10.4 MT-CYB CD4
32 rheumatoid arthritis interstitial lung disease 10.4 CRP CD4
33 third ventricle chordoid glioma 10.4 CD4 CD34
34 epidural abscess 10.4 CRP CD4
35 angiomatosis 10.4
36 bacterial esophagitis 10.4 CD68 CD4
37 pericardial tuberculosis 10.4 CRP CD4
38 primary syphilis 10.4 CRP CD4
39 urogenital tuberculosis 10.4 CRP CD4
40 breast abscess 10.4 CRP CD4
41 meningovascular neurosyphilis 10.4 CRP CD4
42 pyomyositis 10.4 CRP CD4
43 cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 2 10.4 HTRA1 CRP
44 suppurative lymphadenitis 10.3 CRP CD4
45 splenic abscess 10.3 CRP CD4
46 tertiary syphilis 10.3 CRP CD4
47 mediastinitis 10.3 CRP CD4
48 purulent endophthalmitis 10.3 VEGFA CD4
49 critical illness polyneuropathy 10.3 CS CRP
50 chancroid 10.3 HSPD1 CD4

Graphical network of the top 20 diseases related to Bartonellosis:



Diseases related to Bartonellosis

Symptoms & Phenotypes for Bartonellosis

Drugs & Therapeutics for Bartonellosis

Drugs for Bartonellosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Azithromycin Approved Phase 4 83905-01-5 55185 447043
2
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
3 Anti-Bacterial Agents Phase 4
4 Anti-Infective Agents Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Open Label Study of Prednisone and Azithromycin in the Treatment of Patients With Cat Scratch Disease Unknown status NCT01469702 Phase 4 prednison and azithromycin;prednison, azithromycin;prednison, Azenil

Search NIH Clinical Center for Bartonellosis

Cochrane evidence based reviews: bartonella infections

Genetic Tests for Bartonellosis

Anatomical Context for Bartonellosis

MalaCards organs/tissues related to Bartonellosis:

40
Skin, Bone, Breast, Heart, Lymph Node, Liver, Eye

Publications for Bartonellosis

Articles related to Bartonellosis:

(show top 50) (show all 485)
# Title Authors PMID Year
1
Characterization of Bartonella taylorii Strains in Small Mammals of the Turkish Thrace. 61
33788082 2021
2
First Detection of Bartonella spp. in Small Mammals from Rice Storage and Processing Facilities in Myanmar and Sri Lanka. 61
33810195 2021
3
Bartonella henselae Antibodies in Serum and Oral Fluid Specimens from Cats. 61
33799577 2021
4
Hepatosplenic Bartonellosis in an Immunocompetent Teenager: An Atypical Presentation of Cat-Scratch Disease. 61
33717753 2021
5
Association of Presenting Symptoms With Abnormal Laboratory Values for Vector-Borne Illness - Experience in an Urban Gastroenterology Practice. 61
33511252 2021
6
Genetic diversity of Bartonella species in small mammals in the Qaidam Basin, western China. 61
33462399 2021
7
'We should continue to recommend year-round flea protection for cats and dogs'. 61
33334999 2020
8
Atypical bartonellosis in children: What do we know? 61
33301212 2020
9
Clinicopathologic Features of Tissue Granulomas in Transplant Recipients: A Single Center Study in a Nontuberculosis Endemic Region. 61
33290524 2020
10
Detection of Anaplasma spp. and Bartonella spp. from wild-caught rodents and their ectoparasites in Nakhon Ratchasima Province, Thailand. 61
33207059 2020
11
The clinical spectrum of ocular bartonellosis: a retrospective study at a tertiary centre in Malaysia. 61
33191467 2020
12
First report on Bartonella henselae in dromedary camels (Camelus dromedarius). 61
32777455 2020
13
Molecular Evidence of Bartonella spp. in Rodents: A Study in Pianosa Island, Italy. 61
33182237 2020
14
Bartonella spp. associated with rodents in an urban protected area, Buenos Aires (Argentina). 61
32659525 2020
15
Hepatosplenic bartonellosis in immunocompetent adults: a case series and literature review. 61
32306144 2020
16
Clinical presentation, cardiovascular findings, etiology, and outcome of myocarditis in dogs: 64 cases with presumptive antemortem diagnosis (26 confirmed postmortem) and 137 cases with postmortem diagnosis only (2004-2017). 61
32668360 2020
17
The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis. 61
32678094 2020
18
Bartonella bovis and Bartonella chomelii infection in dairy cattle and their ectoparasites in Algeria. 61
32126432 2020
19
Human vascular endothelial cells express epithelial growth factor in response to infection by Bartonella bacilliformis. 61
32302357 2020
20
Effect of different drugs and drug combinations on killing stationary phase and biofilms recovered cells of Bartonella henselae in vitro. 61
32276590 2020
21
Epizootic Situation of Feline Bartonella Infection in Eastern Poland. 61
32258803 2020
22
Bartonella washoensis infection in red squirrels (Sciurus vulgaris) and their ectoparasites in Lithuania. 61
31760364 2020
23
A case of Bartonella neuroretinitis with macular star diagnosed by clinical, epidemiological, serological, and molecular data: resolution after initiation of antimicrobial therapy. 61
32578704 2020
24
Systemic Bartonellosis Manifesting With Endocarditis and Membranoproliferative Glomerulonephritis. 61
33155512 2020
25
Complete Genome Sequence of Bartonella bacilliformis Strain KC584 (ATCC 35686). 61
31896649 2020
26
Cats as a reservoir of Bartonella henselae for dogs. 61
31885244 2019
27
Molecular detection and characterization of Bartonella spp. in pet cats and dogs in Shenzhen, China. 61
31175861 2019
28
First Report of Bartonella SP. In Sand Flies (Diptera: Psychodidae: Phlebotominae) From Southern Mexico. 61
31647703 2019
29
Bartonella diversity and zoonotic potential in indigenous Tete Veld rats (Aethomys ineptus) from South Africa. 61
31004764 2019
30
Cutaneous manifestations of bartonellosis. 61
31780437 2019
31
Bartonella henselae bacteremia diagnosed post-mortem in a myelodysplastic syndrome patient. 61
31531628 2019
32
[About Carrion street and bartonellosis]. 61
31859777 2019
33
Prevalence and diversity of Bartonella species in small rodents from coastal and continental areas. 61
31451710 2019
34
MULTIMODAL IMAGING OF TWO UNCONVENTIONAL CASES OF BARTONELLA NEURORETINITIS. 61
31348120 2019
35
False Negative Results in Bartonellosis Diagnosis. 61
30730266 2019
36
Isolated conjunctival granuloma as a first manifestation of Parinaud's oculoglandular syndrome: A case report. 61
30886938 2019
37
Human Bartonellosis: An Underappreciated Public Health Problem? 61
31010191 2019
38
Identification of FDA-Approved Drugs with Activity against Stationary Phase Bartonella henselae. 61
31035691 2019
39
Acute Unilateral Vision Loss in a Female Adolescent Due to Ocular Bartonellosis. 61
28398939 2019
40
Current Status of Tick-Borne Diseases in South Korea. 61
30328790 2019
41
A review on the occurrence of companion vector-borne diseases in pet animals in Latin America. 61
30917860 2019
42
Multimodality imaging of multifocal ocular bartonellosis with an optic nerve head mass. 61
30851793 2019
43
Bartonella henselae Infection in Sickle Cell Disease Mice Is Associated with Hyperalgesia. 61
30272535 2019
44
What is the minimum length of gltA gene required for phylogenetic analyzes in Bartonella? 61
30217718 2019
45
Metagenomic Approach to Characterizing Disease Epidemiology in a Disease-Endemic Environment in Northern Thailand. 61
30863381 2019
46
Bartonella infections in cats and dogs including zoonotic aspects. 61
30514361 2018
47
Molecular detection and clinical characteristics of Bartonella bacilliformis, Leptospira spp., and Rickettsia spp. in the Southeastern Peruvian Amazon basin. 61
30514235 2018
48
Untangling the knots: Co-infection and diversity of Bartonella from wild gerbils and their associated fleas. 61
30357977 2018
49
Human Exposure to Novel Bartonella Species from Contact with Fruit Bats. 61
30457529 2018
50
Ocular manifestations of bartonellosis. 61
30124532 2018

Variations for Bartonellosis

Expression for Bartonellosis

Search GEO for disease gene expression data for Bartonellosis.

Pathways for Bartonellosis

Pathways related to Bartonellosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.86 CD68 CD4 CD34

GO Terms for Bartonellosis

Cellular components related to Bartonellosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane GO:0016020 9.47 VEGFA TNFRSF8 SYNJ2BP PECAM1 MT-CYB MT-CO1
2 mitochondrial respiratory chain complex III GO:0005750 8.96 MT-CYB MT-CO1

Biological processes related to Bartonellosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.5 VEGFA PECAM1 CD4
2 response to copper ion GO:0046688 9.37 MT-CYB MT-CO1
3 vascular wound healing GO:0061042 9.26 VEGFA CD34
4 positive regulation of peptidyl-tyrosine autophosphorylation GO:1900086 9.16 VEGFA ACE
5 electron transport coupled proton transport GO:0015990 8.96 MT-CYB MT-CO1
6 glomerular endothelium development GO:0072011 8.62 PECAM1 CD34

Sources for Bartonellosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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