MCID: BSL001
MIFTS: 29

Basilar Artery Insufficiency

Categories: Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Basilar Artery Insufficiency

MalaCards integrated aliases for Basilar Artery Insufficiency:

Name: Basilar Artery Insufficiency 12 15 71
Basilar Artery Syndrome 12

Classifications:



External Ids:

Disease Ontology 12 DOID:223
ICD9CM 34 435.0
MeSH 43 D014715
NCIt 49 C34413
SNOMED-CT 67 64009001
UMLS 71 C0004812

Summaries for Basilar Artery Insufficiency

MalaCards based summary : Basilar Artery Insufficiency, also known as basilar artery syndrome, is related to carotid artery disease and vertebrobasilar insufficiency. An important gene associated with Basilar Artery Insufficiency is TSPAN33 (Tetraspanin 33), and among its related pathways/superpathways are A-beta Pathways: Plaque Formation and APP Metabolism and Dissolution of Fibrin Clot. Affiliated tissues include heart, testes and brain.

Related Diseases for Basilar Artery Insufficiency

Diseases related to Basilar Artery Insufficiency via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 75)
# Related Disease Score Top Affiliating Genes
1 carotid artery disease 28.7 PLG PLAT EEF1A2 COG2
2 vertebrobasilar insufficiency 10.9
3 intracranial sinus thrombosis 10.4 TSPAN33 PLG
4 sagittal sinus thrombosis 10.4 TSPAN33 PLG
5 hemopericardium 10.3 PVR PLG
6 basal ganglia cerebrovascular disease 10.3 PLG PLAT
7 anterior cerebral artery infarction 10.3 PLG PLAT
8 ligneous conjunctivitis 10.3 PLG PLAT
9 acute cor pulmonale 10.3 PLG PLAT
10 acute pulmonary heart disease 10.3 PLG PLAT
11 marantic endocarditis 10.3 PLG PLAT
12 brain stem infarction 10.3 PLG PLAT
13 thoracic outlet syndrome 10.3 PLG PLAT
14 inferior myocardial infarction 10.3 PLG PLAT
15 conversion disorder 10.3 PLG PLAT
16 vitreous detachment 10.2 PLG PLAT
17 central retinal artery occlusion 10.2 PLG PLAT
18 middle cerebral artery infarction 10.2 PLG PLAT
19 carotid artery thrombosis 10.2 PLG PLAT
20 obstructive hydrocephalus 10.2 PLG PLAT
21 encephalopathy, familial, with neuroserpin inclusion bodies 10.2 PLG PLAT
22 coronary restenosis 10.2 PLAT CETP
23 subclavian steal syndrome 10.2
24 occlusion precerebral artery 10.2 TSPAN33 PLG PLAT
25 carotid artery occlusion 10.2 TSPAN33 PLG PLAT
26 cardiac tamponade 10.1 PVR PLAT
27 post-thrombotic syndrome 10.1 PLG PLAT
28 intracranial thrombosis 10.1 PLG PLAT
29 intracranial embolism 10.1 PVR PLG PLAT
30 heart conduction disease 10.1 PVR PLG PLAT
31 thrombophilia due to activated protein c resistance 10.1 PLG PLAT
32 atrial heart septal defect 10.0 PVR PLG PLAT
33 thrombophlebitis 10.0 PLG PLAT
34 basilar artery occlusion 10.0 TSPAN33 PLG PLAT DFFA
35 cerebral arterial disease 10.0 TSPAN33 PLG PLAT DFFA
36 ptosis 10.0
37 pure autonomic failure 10.0
38 central retinal vein occlusion 10.0 PLG PLAT
39 macular degeneration, age-related, 2 10.0 SAMHD1 PLAT
40 sudden infant death syndrome 9.9
41 branchiootic syndrome 1 9.9
42 pathologic nystagmus 9.9
43 patent foramen ovale 9.9 SLC22A4 PVR PLG PLAT
44 malignant essential hypertension 9.9 SAMHD1 HMGCR
45 atrial standstill 1 9.8
46 ocular motor apraxia 9.8
47 kearns-sayre syndrome 9.8
48 aphasia 9.8
49 hemosiderosis 9.8
50 neutropenia 9.8

Comorbidity relations with Basilar Artery Insufficiency via Phenotypic Disease Network (PDN): (show all 22)


Acute Cystitis Anxiety
Aortic Valve Disease 1 Benign Essential Hypertension
Cerebral Atherosclerosis Cerebrovascular Disease
Deficiency Anemia Esophagitis
Familial Atrial Fibrillation Generalized Atherosclerosis
Heart Disease Hypertension, Essential
Hypothyroidism Intermediate Coronary Syndrome
Labyrinthitis Malignant Essential Hypertension
Mitral Valve Disease Peripheral Vascular Disease
Sinoatrial Node Disease Transient Cerebral Ischemia
Vertebral Artery Insufficiency Vertigo, Benign Recurrent

Graphical network of the top 20 diseases related to Basilar Artery Insufficiency:



Diseases related to Basilar Artery Insufficiency

Symptoms & Phenotypes for Basilar Artery Insufficiency

Drugs & Therapeutics for Basilar Artery Insufficiency

Search Clinical Trials , NIH Clinical Center for Basilar Artery Insufficiency

Genetic Tests for Basilar Artery Insufficiency

Anatomical Context for Basilar Artery Insufficiency

MalaCards organs/tissues related to Basilar Artery Insufficiency:

40
Heart, Testes, Brain

Publications for Basilar Artery Insufficiency

Articles related to Basilar Artery Insufficiency:

(show top 50) (show all 62)
# Title Authors PMID Year
1
Patterns and Outcomes of the Top of the Basilar Artery Syndrome: The Role of the Posterior Communicating Artery. 61
30199876 2018
2
Rhinocerebral Mucormycosis with Top of Basilar Artery Syndrome. 61
26584534 2016
3
Top of Basilar Artery Syndrome. 61
26393183 2015
4
Rostral basilar artery syndrome following transsphenoidal surgery--a report of four cases. 61
23584392 2013
5
Safe implementation of mechanical thrombectomy in acute stroke patients with major arterial occlusion and concomitant subdural hematoma. 61
24024077 2013
6
Topographic patterns of thalamic infarcts in association with stroke syndromes and aetiologies. 61
21406535 2011
7
TCD diastolic velocity decay and pulsatility index increment in PVS cases. 61
21059547 2010
8
Takotsubo cardiomyopathy associated with top of the basilar artery syndrome. 61
19267172 2009
9
Thrombosis of a fusiform intracranial aneurysm induced by overlapping neuroform stents: case report. 61
17460508 2007
10
Severe ethylene glycol intoxication mimicking acute basilar artery occlusion. 61
16174889 2005
11
Bithalamic infarcts: embolism of the top of basilar artery or deep cerebral venous thrombosis? 61
15297013 2004
12
[Analysis of vascular vertigo due to cervical spondylosis and vertebro-basilar insufficiency based on sex and age in clinical materials]. 61
15101267 2004
13
[Blood flow of the vertebral artery in cases of pontine high intensity area identified by T2-weighted MRI--a study with ultrasonography of vertebral arteries]. 61
11808356 2001
14
Syndrome of cervical spondylosis in Blantyre, Malawi. 61
10734509 1999
15
Local intra-arterial fibrinolysis without arterial occlusion? 61
10450851 1999
16
[Top of the basilar artery syndrome: clinico-radiological aspects of 25 patients]. 61
10363297 1999
17
[Basilar artery insufficiency--a possible cause of sudden infant death? Results of a Doppler ultrasound study of 39 children with apparent life-threatening events]. 61
10028559 1998
18
[Basilar artery insufficiency--a possible cause of sudden infant death?]. 61
10028557 1998
19
Tissue plasminogen activator in a vertebral artery dissection. 61
9164694 1997
20
Bilateral ophthalmoplegia: an unusual sign of the top of the basilar artery syndrome. 61
8915763 1996
21
Multiple acute infarcts in the posterior circulation. 61
8609506 1996
22
[Limb shaking and loss of consciousness: a carotid-basilar artery syndrome]. 61
7893513 1995
23
[Multivariate analysis of everyday handicap of patients with dizziness]. 61
7897572 1995
24
"Top of the basilar artery" syndrome and thalamic aphasia: A case report. 61
26486951 1995
25
Transverse process fractures of the cervical vertebrae: are they insignificant? 61
8315673 1993
26
Types of basilar artery syndrome: clinicoradiologic correlation. 61
8480914 1993
27
[Trimetazidine therapy in atrio-cochlear disturbances of vascular origin]. 61
8415248 1993
28
Cerebellar infarction in the territory of the superior cerebellar artery: a clinicopathologic study of 33 cases. 61
2392223 1990
29
The rostral basilar artery syndrome: diagnosis, etiology, prognosis. 61
2909918 1989
30
Bilateral retinopathy and encephalopathy. 61
2920907 1989
31
The neuro-ophthalmologic spectrum of the rostral basilar artery syndrome. 61
3415527 1988
32
Dynamic amaurosis fugax secondary to compression of vertebral artery. 61
3044227 1988
33
Reversible rostral basilar artery syndrome. 61
3337591 1988
34
[Doppler ultrasound method in the study of vertigo syndrome]. 61
3523306 1986
35
The management of brachiocephalic occlusive disease. 61
6354029 1983
36
A new nystagmographic test for the elicitation of sub-clinical vertebro-basilar insufficiency and poor cochleo-vestibular vascularization. 61
315981 1979
37
Surgical treatment of the acute stroke caused by proven vertebral-basilar artery insufficiency. 61
677570 1978
38
[Vertebral-basilar artery insufficiency nystagmus (author's transl)]. 61
666225 1978
39
Surgical treatment of vertebral artery insufficiency in patients with diagnosis of multiple sclerosis. 61
615387 1977
40
[Results of angiographic investigations in basilar artery insufficiency (author's transl)]. 61
844412 1977
41
[Vertebral and basilar artery insufficiency]. 61
967297 1976
42
[Simple method of differential diagnosis of peripheral and central vertigo--development of diagnostic method and studies of 178 cases]. 61
1036043 1976
43
Enlargement of an arteriovenous malformation documented by angiography. Case report. 61
1194947 1975
44
Cerebral thromboembolism secondary to subclavian artery trauma: report of a case. 61
1152083 1975
45
A comparison of betahistine hydrochloride with placebo for vertebral-basilar insufficiency: a double-blind study. 61
1092033 1975
46
[Neurologic complications of pagetic basilar impressions and their surgical treatment]. 61
166440 1975
47
[Acute bilateral deafness in basilar artery insufficiency]. 61
4646138 1972
48
Basilar artery insufficiency due to atlanto-occipital instability. 61
5824341 1969
49
Vertigo: epileptic manifestation of vertebral-basilar artery insufficiency. 61
5257903 1969
50
Acute hypercalcemia simulating basilar-artery insufficiency. 61
5304106 1969

Variations for Basilar Artery Insufficiency

Expression for Basilar Artery Insufficiency

Search GEO for disease gene expression data for Basilar Artery Insufficiency.

Pathways for Basilar Artery Insufficiency

Pathways related to Basilar Artery Insufficiency according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.32 PLG PLAT
2 9.74 PLG PLAT

GO Terms for Basilar Artery Insufficiency

Cellular components related to Basilar Artery Insufficiency according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 tetraspanin-enriched microdomain GO:0097197 8.62 TSPAN33 SAMHD1

Biological processes related to Basilar Artery Insufficiency according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of osteoclast differentiation GO:0045671 9.26 TOB2 CALCA
2 fibrinolysis GO:0042730 9.16 PLG PLAT
3 myoblast differentiation GO:0045445 8.96 PLG HMGCR
4 trans-synaptic signaling by BDNF, modulating synaptic transmission GO:0099183 8.62 PLG PLAT

Molecular functions related to Basilar Artery Insufficiency according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.47 ZNF143 TSPAN33 TOB2 SLC22A4 SAMHD1 PVR

Sources for Basilar Artery Insufficiency

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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