MCID: BSL004
MIFTS: 33

Basilar Artery Occlusion

Categories: Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Basilar Artery Occlusion

MalaCards integrated aliases for Basilar Artery Occlusion:

Name: Basilar Artery Occlusion 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:13446
ICD9CM 34 433.0
SNOMED-CT 67 78658006
ICD10 32 I65.1
UMLS 70 C0265098

Summaries for Basilar Artery Occlusion

MalaCards based summary : Basilar Artery Occlusion is related to brain stem infarction and vertebral artery occlusion. An important gene associated with Basilar Artery Occlusion is PLAT (Plasminogen Activator, Tissue Type), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Selenium Micronutrient Network. The drugs Tissue Plasminogen Activator and Plasminogen have been mentioned in the context of this disorder. Affiliated tissues include heart, brain and pons.

Related Diseases for Basilar Artery Occlusion

Diseases related to Basilar Artery Occlusion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 160)
# Related Disease Score Top Affiliating Genes
1 brain stem infarction 30.9 PLG PLAT
2 vertebral artery occlusion 30.8 PLG PLAT
3 stroke, ischemic 30.3 PLG PLAT F2
4 basilar artery insufficiency 30.3 PLG PLAT
5 carotid artery occlusion 30.2 PLG PLAT
6 acute myocardial infarction 30.1 PLG PLAT ITGA2B
7 thoracic outlet syndrome 29.9 PLG F2
8 cerebrovascular disease 29.8 PLAT ITGA2B F2
9 intracranial embolism 29.6 PLG PLAT F2
10 cardiac tamponade 29.6 PLG PLAT F2
11 thrombosis 29.5 PLG PLAT ITGA2B F2
12 myocardial infarction 29.5 PLG PLAT ITGA2B F2
13 ocular motor apraxia 10.8
14 locked-in syndrome 10.5
15 hemiplegia 10.4
16 quadriplegia 10.4
17 pica disease 10.4
18 aneurysm 10.4
19 ataxia and polyneuropathy, adult-onset 10.3
20 branchiootic syndrome 1 10.3
21 hydrocephalus 10.3
22 asplenia, isolated congenital 10.2
23 myocardial infarction 2 10.2
24 cerebral artery occlusion 10.2
25 vertebrobasilar insufficiency 10.2
26 transient cerebral ischemia 10.2
27 basal ganglia cerebrovascular disease 10.2 PLG PLAT
28 ligneous conjunctivitis 10.2 PLG PLAT
29 inferior myocardial infarction 10.2 PLG PLAT
30 plasminogen deficiency, type i 10.2 PLG PLAT
31 conversion disorder 10.2 PLG PLAT
32 perforated corneal ulcer 10.2 PLG PLAT
33 hereditary angioedema 10.2 PLG PLAT
34 hereditary angioedema with normal c1inh 10.2 PLG PLAT
35 middle cerebral artery infarction 10.2 PLG PLAT
36 acute anterolateral myocardial infarction 10.2 PLG ITGA2B
37 lateral myocardial infarction 10.2 PLG ITGA2B
38 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.1
39 kearns-sayre syndrome 10.1
40 yemenite deaf-blind hypopigmentation syndrome 10.1
41 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.1
42 sensorineural hearing loss 10.1
43 mutism 10.1
44 mucormycosis 10.1
45 47,xyy 10.1
46 cerebral aneurysms 10.1
47 dysphagia 10.1
48 tremor 10.1
49 pediatric arterial ischemic stroke 10.1
50 hepatic veno-occlusive disease 10.1 PLG PLAT

Graphical network of the top 20 diseases related to Basilar Artery Occlusion:



Diseases related to Basilar Artery Occlusion

Symptoms & Phenotypes for Basilar Artery Occlusion

Drugs & Therapeutics for Basilar Artery Occlusion

Drugs for Basilar Artery Occlusion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Tissue Plasminogen Activator
2 Plasminogen

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Basilar Artery International Cooperation Study Unknown status NCT01717755
2 Acute Basilar Artery Occlusion: Endovascular Interventions vs Standard Medical Treatment Completed NCT02441556
3 DWI Cerebellar Infarct Volume as Predictor of Outcomes After Endovascular Treatment of Acute Basilar Artery Occlusion Completed NCT04611178
4 Predicting Value of DWI Total Posterior-circulation Infarct Volume for Endovascular Treatment Outcomes of Acute Basilar Artery Occlusion Completed NCT04650022
5 Randomized Trial of Revascularization With Solitaire Stentriever Versus Best Medical Therapy in the Treatment of Acute Ischemic Stroke Due to Basilar Artery Occlusion Presenting Within 6-24 Hours of Symptom Onset Recruiting NCT02737189 Medical Treatment
6 Endovascular Treatment for Acute Basilar Artery Occlusion - a Multicenter Randomized Clinical Trial Recruiting NCT04751708
7 Randomized Assessment of Rapid Endovascular Treatment in Basilar Artery Occlusion Stroke in 115 Hospital Not yet recruiting NCT04177615

Search NIH Clinical Center for Basilar Artery Occlusion

Genetic Tests for Basilar Artery Occlusion

Anatomical Context for Basilar Artery Occlusion

MalaCards organs/tissues related to Basilar Artery Occlusion:

40
Heart, Brain, Pons, Cerebellum, Cortex, Kidney

Publications for Basilar Artery Occlusion

Articles related to Basilar Artery Occlusion:

(show top 50) (show all 672)
# Title Authors PMID Year
1
Predicting mortality in acute ischaemic stroke treated with mechanical thrombectomy: analysis of a multicentre prospective registry. 61
33795300 2021
2
Analysis of Treatment Outcome After Endovascular Treatment in Different Pathological Subtypes of Basilar Artery Occlusion: a Single Center Experience. 61
32638233 2021
3
Hyperdense basilar artery identified on unenhanced head CT in three cases of pediatric basilar artery occlusion. 61
33309508 2021
4
Endovascular treatment of acute basilar artery occlusion: Outcomes, influencing factors and imaging characteristics from the Tama-REgistry of acute thrombectomy (TREAT) study. 61
33775325 2021
5
Focal brainstem infarction in the adult rat. 61
33564191 2021
6
Endovascular revascularization of chronically occluded vertebral artery: single-center experience. 61
33786136 2021
7
Fast and slow progressors of infarct growth in basilar artery occlusion strokes. 61
33766940 2021
8
Endovascular recanalization for non-acute basilar artery occlusions with progressive or recurrent ischemic symptoms: a multicenter clinical experience. 61
33674396 2021
9
Tenecteplase vs Alteplase Before Endovascular Therapy in Basilar Artery Occlusion. 61
33408145 2021
10
Impact of the Perioperative Blood Pressure on Clinical Outcome after Thrombectomy in Acute Basilar Artery Occlusion. 61
33583512 2021
11
Outcomes and long-term mortality after basilar artery occlusion-A cohort with up to 20 years' follow-up. 61
33141492 2021
12
Posterior Circulation Endovascular Thrombectomy for Large-Vessel Occlusion: Predictors of Favorable Clinical Outcome and Analysis of First-Pass Effect. 61
33664106 2021
13
Thrombectomy for Comatose Patients with Basilar Artery Occlusion : A Multicenter Study. 61
33704508 2021
14
Characteristics and prognosis of acute basilar artery occlusion in minor to moderate stroke and severe stroke after endovascular treatment: A multicenter retrospective study. 61
33535127 2021
15
Values of Baseline Posterior Circulation Acute Stroke Prognosis Early Computed Tomography Score for Treatment Decision of Acute Basilar Artery Occlusion. 61
33567874 2021
16
Thrombectomy for Posterior Circulation Stroke: Predictors of Outcomes in a Brazilian Registry. 61
33346048 2021
17
Basilar artery occlusion presenting as sudden bilateral deafness: a case report. 61
33653404 2021
18
Predictive value on diffusion weighted imaging scores for basilar artery occlusion after endovascular treatment. 61
32640857 2021
19
Basilar Artery Occlusion and Emerging Treatments. 61
33469899 2021
20
Superficial temporal artery-posteriorcerebral artery bypass for the treatment of chronic basilar artery occlusion. 61
33631388 2021
21
Association of pretreatment pontine infarction with extremely poor outcome after endovascular thrombectomy in acute basilar artery occlusion. 61
32447299 2021
22
Von Leyden's Contribution to the Elusive Syndrome of Acute Basilar Artery Occlusion. 61
33558956 2021
23
Involvement of Supraoptic Astrocytes in Basilar Artery Occlusion-Evoked Differential Activation of Vasopressin Neurons and Vasopressin Secretion in Rats. 61
33532897 2021
24
Thrombectomy for Basilar Artery Occlusion with Mild Symptoms. 61
33578025 2021
25
Clot Meniscus Sign: An Angiographic Clue for Choosing between Stent Retriever and Contact Aspiration in Acute Basilar Artery Occlusion. 61
33541894 2021
26
Age and discharge modified Rankin score are associated with 90-Day functional outcome after basilar artery occlusion treated with endovascular therapy. 61
33412967 2021
27
Neurological improvement predicts clinical outcome after acute basilar artery stroke thrombectomy. 61
32812674 2021
28
Inner-Ear Symptom May Herald Basilar Artery Occlusion. 61
33613241 2021
29
Factors influencing early neurological improvement after mechanical thrombectomy among patients with acute basilar artery occlusion: a single center prospective observational cohort study. 61
32488830 2021
30
First pass effect in patients with large vessel occlusion strokes undergoing neurothrombectomy: insights from the Trevo Retriever Registry. 61
33479032 2021
31
Endovascular treatment for basilar artery occlusion: A systematic review and meta-analysis. 61
33482047 2021
32
Intended Bridging Therapy or Intravenous Thrombolysis Alone in Minor Stroke With Basilar Artery Occlusion. 61
33406868 2021
33
Basilar artery occlusion syndrome with diplopia, ataxia, and encephalopathy. 61
33443854 2021
34
Intravenous Propofol Versus Volatile Anesthetics For Stroke Endovascular Thrombectomy. 61
31453877 2021
35
Coronary stent implantation for acute basilar artery occlusion with underlying stenosis. 61
31355751 2020
36
Mechanical Thrombectomy for Posterior Circulation Occlusion: A Comparison of Outcomes with the Anterior Circulation Occlusion - A Meta-Analysis. 61
32062629 2020
37
A Pre-Intervention 4-Item Scale for Predicting Poor Outcome Despite Successful Recanalization in Basilar Artery Occlusion. 61
32318917 2020
38
Recanalization is the Key for Better Outcome of Thrombectomy in Basilar Artery Occlusion. 61
31872288 2020
39
Outcome and recanalization rate of tandem basilar artery occlusion treated by mechanical thrombectomy. 61
32910987 2020
40
DWI cerebellar infarct volume as predictor of outcomes after endovascular treatment of acute basilar artery occlusion. 61
33243771 2020
41
Effect of manual aspiration thrombectomy using large-bore aspiration catheter for acute basilar artery occlusion: comparison with a stent retriever system. 61
33250061 2020
42
Predicting outcomes after acute reperfusion therapy for basilar artery occlusion. 61
32558040 2020
43
Endovascular treatment versus standard medical treatment for acute basilar artery occlusion: protocol for a systematic review and meta-analysis. 61
33247016 2020
44
Quantification of Cerebral Perfusion using Laser Speckle Imaging and Infarct Volume using MRI in a Pre-clinical Model of Posterior Circulation Stroke. 61
33283781 2020
45
Treatment Outcomes by Initial Neurological Deficits in Acute Stroke Patients with Basilar Artery Occlusion: The RESCUE Japan Registry 2. 61
33066937 2020
46
Endovascular clot retrieval for acute ischaemic stroke due to basilar artery occlusion in childhood. 61
31898325 2020
47
Effect of anesthesia strategy during endovascular therapy on 90-day outcomes in acute basilar artery occlusion: a retrospective observational study. 61
33121454 2020
48
Presenting NIHSS predicts 90-day functional outcome after mechanical thrombectomy for basilar artery occlusion: A systematic review and meta-analysis. 61
32916397 2020
49
Looking Twice the Wrong Way: The Challenge of Diagnosing Acute Basilar Artery Occlusion. 61
33033961 2020
50
Predictors of Very Poor Outcome after Mechanical Thrombectomy for Acute Basilar Artery Occlusion. 61
32879183 2020

Variations for Basilar Artery Occlusion

Expression for Basilar Artery Occlusion

Search GEO for disease gene expression data for Basilar Artery Occlusion.

Pathways for Basilar Artery Occlusion

GO Terms for Basilar Artery Occlusion

Cellular components related to Basilar Artery Occlusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.35 PLG PLAT ITGA2B F2 CHMP2A
2 collagen-containing extracellular matrix GO:0062023 9.33 PLG PLAT F2
3 blood microparticle GO:0072562 8.8 PLG ITGA2B F2

Biological processes related to Basilar Artery Occlusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blood coagulation GO:0007596 9.33 PLG PLAT F2
2 hemostasis GO:0007599 9.32 PLG F2
3 negative regulation of proteolysis GO:0045861 9.26 PLAT F2
4 negative regulation of fibrinolysis GO:0051918 8.96 PLG F2
5 fibrinolysis GO:0042730 8.8 PLG PLAT F2

Molecular functions related to Basilar Artery Occlusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor binding GO:0005102 9.33 PLG PLAT F2
2 serine-type endopeptidase activity GO:0004252 9.13 PLG PLAT F2
3 serine-type peptidase activity GO:0008236 8.8 PLG PLAT F2

Sources for Basilar Artery Occlusion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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