MCID: BSP001
MIFTS: 20

Basophil Adenoma

Categories: Blood diseases, Cancer diseases, Endocrine diseases

Aliases & Classifications for Basophil Adenoma

MalaCards integrated aliases for Basophil Adenoma:

Name: Basophil Adenoma 12 15 17
Adenoma, Basophil 45 74
Pituitary Gland Basophilic Adenoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4542
MeSH 45 D000237
NCIt 51 C2856
SNOMED-CT 69 9436005
UMLS 74 C0001431

Summaries for Basophil Adenoma

MalaCards based summary : Basophil Adenoma, also known as adenoma, basophil, is related to mixed eosinophil-basophil adenoma and adenoma. An important gene associated with Basophil Adenoma is POMC (Proopiomelanocortin). The drugs Hormones and Dexamethasone have been mentioned in the context of this disorder. Affiliated tissues include pituitary and t cells.

Related Diseases for Basophil Adenoma

Diseases related to Basophil Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 mixed eosinophil-basophil adenoma 12.4
2 adenoma 10.3
3 steatorrhea 9.9
4 conn's syndrome 9.9
5 goiter 9.9

Graphical network of the top 20 diseases related to Basophil Adenoma:



Diseases related to Basophil Adenoma

Symptoms & Phenotypes for Basophil Adenoma

Drugs & Therapeutics for Basophil Adenoma

Drugs for Basophil Adenoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 15)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Hormones Phase 2,Phase 1
2
Dexamethasone Approved, Investigational, Vet_approved Phase 1 50-02-2 5743
3
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 1 1177-87-3
4
protease inhibitors Phase 1
5 Peripheral Nervous System Agents Phase 1
6 Hormone Antagonists Phase 1
7 Antiemetics Phase 1
8 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 1
9 Gastrointestinal Agents Phase 1
10 Autonomic Agents Phase 1
11 HIV Protease Inhibitors Phase 1
12 glucocorticoids Phase 1
13 BB 1101 Phase 1
14 Anti-Inflammatory Agents Phase 1
15 Antineoplastic Agents, Hormonal Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Temozolomide in Treating Patients With Invasive Pituitary Tumors Withdrawn NCT00601289 Phase 2 temozolomide
2 Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia Terminated NCT01088763 Phase 1 gamma-secretase/Notch signalling pathway inhibitor RO4929097;dexamethasone

Search NIH Clinical Center for Basophil Adenoma

Cochrane evidence based reviews: adenoma, basophil

Genetic Tests for Basophil Adenoma

Anatomical Context for Basophil Adenoma

MalaCards organs/tissues related to Basophil Adenoma:

42
Pituitary, T Cells

Publications for Basophil Adenoma

Articles related to Basophil Adenoma:

# Title Authors Year
1
Cyclical Cushing's disease: two distinct rhythms in a patient with a basophil adenoma. ( 2981244 )
1985
2
Cyproheptadine-induced remission of Cushing's disease due to pituitary basophil adenoma. ( 6295736 )
1982
3
Pars intermedia basophil adenoma of the hypophysis. ( 19970391 )
1938
4
BASOPHIL ADENOMA OF THE PITUITARY GLAND WITH RENAL CHANGES. ( 20778876 )
1935
5
Cardiovascular Renal Changes Associated with Basophil Adenoma of the Anterior Lobe of the Pituitary (Cushing's Syndrome). ( 19970135 )
1934

Variations for Basophil Adenoma

Expression for Basophil Adenoma

Search GEO for disease gene expression data for Basophil Adenoma.

Pathways for Basophil Adenoma

GO Terms for Basophil Adenoma

Sources for Basophil Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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