MCID: BSP001
MIFTS: 20

Basophil Adenoma

Categories: Blood diseases, Cancer diseases, Endocrine diseases

Aliases & Classifications for Basophil Adenoma

MalaCards integrated aliases for Basophil Adenoma:

Name: Basophil Adenoma 12 15 17
Adenoma, Basophil 44 72
Pituitary Gland Basophilic Adenoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4542
MeSH 44 D000237
NCIt 50 C2856
SNOMED-CT 68 9436005
UMLS 72 C0001431

Summaries for Basophil Adenoma

MalaCards based summary : Basophil Adenoma, also known as adenoma, basophil, is related to mixed eosinophil-basophil adenoma and adenoma. An important gene associated with Basophil Adenoma is POMC (Proopiomelanocortin). The drugs Dexamethasone and Dexamethasone acetate have been mentioned in the context of this disorder. Affiliated tissues include pituitary and t cells.

Related Diseases for Basophil Adenoma

Diseases related to Basophil Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 11)
# Related Disease Score Top Affiliating Genes
1 mixed eosinophil-basophil adenoma 12.5
2 adenoma 10.5
3 myxedema 10.0
4 pituitary adenoma 4, acth-secreting 9.9
5 steatorrhea 9.9
6 conn's syndrome 9.9
7 goiter 9.9
8 adrenal carcinoma 9.9
9 acth-secreting pituitary adenoma 9.9
10 pituitary tumors 9.9
11 acromegaly 9.9

Graphical network of the top 20 diseases related to Basophil Adenoma:



Diseases related to Basophil Adenoma

Symptoms & Phenotypes for Basophil Adenoma

Drugs & Therapeutics for Basophil Adenoma

Drugs for Basophil Adenoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 15)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 1 50-02-2 5743
2
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 1 1177-87-3
3 Hormone Antagonists Phase 1
4 Antiemetics Phase 1
5 Gastrointestinal Agents Phase 1
6 HIV Protease Inhibitors Phase 1
7 Anti-Inflammatory Agents Phase 1
8 glucocorticoids Phase 1
9 Hormones Phase 1
10
protease inhibitors Phase 1
11 Peripheral Nervous System Agents Phase 1
12 Antineoplastic Agents, Hormonal Phase 1
13 BB 1101 Phase 1
14 Autonomic Agents Phase 1
15 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A PHASE 1/2 STUDY OF RO4929097, AN ORAL SMALL MOLECULE INHIBITOR OF GAMMA-SECRETASE, IN CHILDREN WITH RELAPSED/REFRACTORY SOLID OR CNS TUMORS, LYMPHOMA, OR T-CELL LEUKEMIA Terminated NCT01088763 Phase 1 gamma-secretase/Notch signalling pathway inhibitor RO4929097;dexamethasone

Search NIH Clinical Center for Basophil Adenoma

Cochrane evidence based reviews: adenoma, basophil

Genetic Tests for Basophil Adenoma

Anatomical Context for Basophil Adenoma

MalaCards organs/tissues related to Basophil Adenoma:

41
Pituitary, T Cells

Publications for Basophil Adenoma

Articles related to Basophil Adenoma:

(show all 17)
# Title Authors PMID Year
1
Transnasal stereotactic surgery of pituitary adenomas concomitant with acromegaly. 38
8916351 1995
2
[Genetic aspects of renal tumors in adults]. 38
1304117 1992
3
Cushing's disease in a young woman with anorexia nervosa: pathophysiological implications. 38
3026602 1986
4
Cyclical Cushing's disease: two distinct rhythms in a patient with a basophil adenoma. 38
2981244 1985
5
Mania in Cushing's syndrome: case report. 38
6317660 1983
6
Cyproheptadine-induced remission of Cushing's disease due to pituitary basophil adenoma. 38
6295736 1982
7
Electroconvulsive therapy following pituitary surgery. 38
41885 1979
8
Pregnancy and Nelson's syndrome. Two case reports. 38
698156 1978
9
Cushing's syndrome, nodular adrenal hyperplasia and virilizing carcinoma. 38
209918 1978
10
[Pituitary adenoma with alpha, 17-39 ACTH and beta, MSH cells, without hypercorticism (author's transl)]. 38
207217 1978
11
Treatment of Nelson's syndrome by pituitary implantation of yttrium-90 or gold-198. 38
182313 1976
12
[Mixed adenoma (basophil & eosinophil) of the pituitary, with bitemporal hemianopsia, Cushing syndrome and acromegaly]. 38
13579569 1958
13
[Cushing's disease with basophil adenoma]. 38
12994178 1952
14
[Basophil adenoma with slow evolution and virilism]. 38
12980573 1952
15
Pars intermedia basophil adenoma of the hypophysis. 38
19970391 1938
16
BASOPHIL ADENOMA OF THE PITUITARY GLAND WITH RENAL CHANGES. 38
20778876 1935
17
Cardiovascular Renal Changes Associated with Basophil Adenoma of the Anterior Lobe of the Pituitary (Cushing's Syndrome). 38
19970135 1934

Variations for Basophil Adenoma

Expression for Basophil Adenoma

Search GEO for disease gene expression data for Basophil Adenoma.

Pathways for Basophil Adenoma

GO Terms for Basophil Adenoma

Sources for Basophil Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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