MCID: BSS001
MIFTS: 29

Basosquamous Carcinoma

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Basosquamous Carcinoma

MalaCards integrated aliases for Basosquamous Carcinoma:

Name: Basosquamous Carcinoma 12 15
Carcinoma, Basosquamous 45 74
Basisquamous Cell Carcinoma 12
Basosquamous Cell Carcinoma 12
Metatypical Carcinoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5063
MeSH 45 D002281
NCIt 51 C2922
SNOMED-CT 69 37304002 6641007
UMLS 74 C0007118

Summaries for Basosquamous Carcinoma

MalaCards based summary : Basosquamous Carcinoma, also known as carcinoma, basosquamous, is related to metatypical basal cell carcinoma and basal cell carcinoma 1. An important gene associated with Basosquamous Carcinoma is SLC12A2 (Solute Carrier Family 12 Member 2), and among its related pathways/superpathways is Colorectal Cancer Metastasis. The drugs nivolumab and Talimogene laherparepvec have been mentioned in the context of this disorder. Affiliated tissues include skin, bone and lymph node, and related phenotype is cardiovascular system.

Related Diseases for Basosquamous Carcinoma

Graphical network of the top 20 diseases related to Basosquamous Carcinoma:



Diseases related to Basosquamous Carcinoma

Symptoms & Phenotypes for Basosquamous Carcinoma

MGI Mouse Phenotypes related to Basosquamous Carcinoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 8.92 IDO1 PTGER4 SLC12A2 TP53

Drugs & Therapeutics for Basosquamous Carcinoma

Drugs for Basosquamous Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
nivolumab Approved Phase 2 946414-94-4
2
Talimogene laherparepvec Approved, Experimental, Investigational Phase 2 1187560-31-1
3 Antineoplastic Agents, Immunological Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers Recruiting NCT02978625 Phase 2

Search NIH Clinical Center for Basosquamous Carcinoma

Cochrane evidence based reviews: carcinoma, basosquamous

Genetic Tests for Basosquamous Carcinoma

Anatomical Context for Basosquamous Carcinoma

MalaCards organs/tissues related to Basosquamous Carcinoma:

42
Skin, Bone, Lymph Node, Bone Marrow, Pancreas, Appendix

Publications for Basosquamous Carcinoma

Articles related to Basosquamous Carcinoma:

(show top 50) (show all 56)
# Title Authors Year
1
Complete response of locally advanced basosquamous carcinoma to vismodegib in two patients. ( 30998204 )
2019
2
Basal cell carcinoma and basosquamous carcinoma, two faces of the same condition? ( 30534845 )
2018
3
Perineural spread of basosquamous carcinoma to the orbit, cavernous sinus, and infratemporal fossa. ( 29053047 )
2018
4
Primary basosquamous carcinoma of the lower eyelid with ocular invasion A case report. ( 29626183 )
2018
5
Sentinel lymph node metastasis in primary cutaneous basosquamous carcinoma. A cross-sectional study. ( 29714816 )
2018
6
Basosquamous Carcinoma: A Single Centre Clinicopathological Evaluation and Proposal of an Evidence-Based Protocol. ( 29973992 )
2018
7
Detection of Felis catus papillomavirus type 2 within multicentric basosquamous carcinoma in a domestic cat. ( 29998924 )
2018
8
Complete response of locally advanced basosquamous carcinoma to vismodegib in two patients. ( 30530415 )
2018
9
Basosquamous Carcinoma: Controversy, Advances, and Future Directions. ( 27340741 )
2017
10
Basosquamous carcinoma: Dermoscopic clues to diagnosis. ( 27570202 )
2017
11
Basosquamous carcinoma: appearance and reality. ( 28058108 )
2017
12
Reflectance confocal microscopic presentation of basosquamous carcinoma. ( 28622414 )
2017
13
Host immune responses and peritumoral stromal reactions in different basal cell carcinoma subtypes: histopathological comparison of basosquamous carcinoma and high-risk and low-risk basal cell carcinoma subtypes. ( 27511329 )
2016
14
Basosquamous Carcinoma Masquerading as Angiolymphoid Hyperplasia. ( 26955161 )
2016
15
Rescue therapy with anti-programmed cell death protein 1 inhibitors of advanced cutaneous squamous cell carcinoma and basosquamous carcinoma: preliminary experience in five cases. ( 27059424 )
2016
16
Metastatic Basosquamous Carcinoma: Report of Two Cases and Clinicopathological Considerations. ( 27235385 )
2016
17
Basosquamous carcinoma: is it an aggressive tumor? ( 25139415 )
2015
18
Basosquamous carcinoma of the head and neck: clinical and histologic characteristics and their impact on disease progression. ( 25810014 )
2015
19
Case of basosquamous carcinoma: Dermoscopic and immunohistochemical findings. ( 26211637 )
2015
20
The Effects of Cyclin D1 and Bcl-2 Expressıon on Aggressive Behavior in Basal Cell and Basosquamous Carcinoma. ( 26351483 )
2015
21
Basosquamous carcinoma and metatypical basal cell carcinoma: a review of treatment with Mohs micrographic surgery. ( 24961583 )
2014
22
Face Basosquamous Carcinoma, a Case Report. ( 26870599 )
2014
23
Dermoscopy of basosquamous carcinoma. ( 23607676 )
2013
24
Metastatic basosquamous carcinoma detected by sentinel lymph node biopsy. ( 23724935 )
2013
25
Features of biopsy in diagnosis of metatypical basal cell carcinoma (Basosquamous Carcinoma) of head and neck. ( 23200564 )
2012
26
Excision and reconstruction of a giant basosquamous carcinoma of the anterior chest wall. ( 22369807 )
2012
27
Basosquamous carcinoma: histopathological features. ( 23112359 )
2012
28
Basosquamous carcinoma involving the anterior skull base: a neglected tumor treated using intraoperative navigation as a guide to achieve safe resection margins. ( 21030128 )
2011
29
Application of sentinel lymph node biopsy in cutaneous basosquamous carcinoma. ( 22028558 )
2011
30
Detection by (18)F-FDG PET of unsuspected extensive bone marrow metastases in a case of basosquamous carcinoma of the cheek. ( 22087455 )
2011
31
Basosquamous carcinoma with systemic metastasis in a miniature Pinscher. ( 22256426 )
2011
32
Basosquamous carcinoma--a rare but aggressive skin malignancy. ( 19647505 )
2010
33
Letter: Re: Metastatic basosquamous carcinoma: report of two cases. ( 20402946 )
2010
34
Recurrence of basosquamous carcinoma after Mohs micrographic surgery. ( 20924160 )
2010
35
Basosquamous carcinoma. ( 19103364 )
2009
36
Crusted facial lesion of two years' duration. Basosquamous carcinoma. ( 19552371 )
2009
37
Metastatic basosquamous carcinoma: report of two cases. ( 19076903 )
2008
38
Basosquamous carcinoma of the lacrimal sac: a case report. ( 18097965 )
2007
39
Basosquamous carcinoma-an under-recognized, high-risk cutaneous neoplasm: case study and review of the literature. ( 16756261 )
2006
40
Genetic characterization of the first chiropteran papillomavirus, isolated from a basosquamous carcinoma in an Egyptian fruit bat: the Rousettus aegyptiacus papillomavirus type 1. ( 16854536 )
2006
41
Papillomavirus-associated basosquamous carcinoma in an Egyptian fruit bat (Rousettus aegyptiacus). ( 17312801 )
2006
42
Basosquamous carcinoma: treatment with Mohs micrographic surgery. ( 15929123 )
2005
43
Cutaneous basosquamous carcinoma infiltrating cerebral tissue. ( 15096148 )
2004
44
Basosquamous carcinoma. ( 12859383 )
2003
45
Advanced case of basosquamous carcinoma of the nose. ( 12866604 )
2003
46
Basosquamous carcinoma of the supraglottic larynx with sudden death from asphyxia. ( 12144087 )
2002
47
Basosquamous carcinoma: analysis of prognostic factors influencing recurrence. ( 10717618 )
2000
48
What is basosquamous carcinoma? ( 10816246 )
2000
49
Basosquamous carcinoma after ultraviolet therapy with artificial sunlight. ( 10487009 )
1999
50
Two unusual tumors in a patient with xeroderma pigmentosum: atypical fibroxanthoma and basosquamous carcinoma. ( 10563498 )
1999

Variations for Basosquamous Carcinoma

Expression for Basosquamous Carcinoma

Search GEO for disease gene expression data for Basosquamous Carcinoma.

Pathways for Basosquamous Carcinoma

Pathways related to Basosquamous Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.84 PTGER4 TP53

GO Terms for Basosquamous Carcinoma

Biological processes related to Basosquamous Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to lipopolysaccharide GO:0032496 8.62 IDO1 PTGER4

Sources for Basosquamous Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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