MCID: BNG014
MIFTS: 26

Benign Breast Adenomyoepithelioma

Categories: Cancer diseases

Aliases & Classifications for Benign Breast Adenomyoepithelioma

MalaCards integrated aliases for Benign Breast Adenomyoepithelioma:

Name: Benign Breast Adenomyoepithelioma 12 15 71
Benign Adenomyoepithelioma of the Breast 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1641
NCIt 49 C5144
UMLS 71 C1332477

Summaries for Benign Breast Adenomyoepithelioma

Disease Ontology : 12 A breast benign neoplasm that is characterized by dual differentiation into luminal cells and myoepithelial cells.

MalaCards based summary : Benign Breast Adenomyoepithelioma, also known as benign adenomyoepithelioma of the breast, is related to rare tumor and limbal stem cell deficiency. An important gene associated with Benign Breast Adenomyoepithelioma is SFN (Stratifin), and among its related pathways/superpathways are Developmental Biology and Keratinization. Affiliated tissues include breast, lung and skin, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Benign Breast Adenomyoepithelioma

Diseases in the Breast Adenomyoepithelioma family:

Benign Breast Adenomyoepithelioma

Diseases related to Benign Breast Adenomyoepithelioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 177)
# Related Disease Score Top Affiliating Genes
1 rare tumor 10.3
2 limbal stem cell deficiency 10.1 SFN KRT14
3 rare breast tumor 10.1
4 skin papilloma 10.0 KRT14 EGFR
5 pregnancy adenoma 10.0 KRT5 KRT14
6 epidermolysis bullosa simplex, autosomal recessive 1 10.0 KRT5 KRT14
7 epidermolysis bullosa simplex 10.0 KRT5 KRT14
8 odontoma 10.0 KRT5 KRT14
9 breast myoepithelial carcinoma 10.0 KRT5 KRT14
10 lipid-rich carcinoma 10.0 KRT5 KRT14
11 breast malignant phyllodes tumor 10.0 KRT5 EGFR
12 epidermolysis bullosa simplex with mottled pigmentation 10.0 KRT5 KRT14
13 micronodular basal cell carcinoma 10.0 KRT5 KRT14
14 epidermolysis bullosa simplex, generalized 10.0 KRT5 KRT14
15 intraductal breast neoplasm 10.0 KRT5 KRT14
16 epidermolysis bullosa simplex, localized 10.0 KRT5 KRT14
17 keratoacanthoma 10.0 KRT14 EGFR
18 intracystic papillary adenoma 10.0 KRT5 KRT14
19 reticulate acropigmentation of kitamura 10.0 KRT5 KRT14
20 intraductal papilloma 10.0 KRT5 KRT14
21 hard palate cancer 10.0 KRT5 KRT14
22 vesiculobullous skin disease 10.0 KRT5 KRT14
23 sebaceous adenocarcinoma 10.0 KRT5 KRT14
24 epidermolysis bullosa simplex, dowling-meara type 10.0 KRT5 KRT14
25 verrucous carcinoma 9.9 KRT5 EGFR
26 pachyonychia congenita 1 9.9 KRT5 KRT14
27 thymus gland disease 9.9 KRT5 EGFR
28 hair disease 9.9 KRT14 EGFR
29 palmoplantar keratoderma, epidermolytic 9.9 KRT5 KRT14
30 dowling-degos disease 9.9 KRT5 KRT14
31 pleural cancer 9.9 KRT5 EGFR
32 skin benign neoplasm 9.9 KRT5 KRT14
33 spiradenoma 9.9 KRT7 KRT14
34 pleural disease 9.9 KRT5 EGFR
35 oncocytic breast carcinoma 9.9 KRT7 KRT14
36 lipoadenoma 9.9 KRT7 KRT14
37 small cell carcinoma 9.9 KRT7 EGFR
38 myoepithelial carcinoma 9.9 KRT7 KRT14
39 lung acinar adenocarcinoma 9.8 KRT7 EGFR
40 epithelioid sarcoma 9.8 KRT7 EGFR
41 horseshoe kidney 9.8 KRT7 EGFR
42 vulvar disease 9.8 KRT7 EGFR
43 epithelial-myoepithelial carcinoma 9.8 KRT7 KRT14
44 inverted transitional papilloma 9.8 KRT7 KRT5
45 anus cancer 9.8 KRT7 EGFR
46 malignant spiradenoma 9.8 KRT7 KRT5
47 ceruminoma 9.8 KRT7 KRT5
48 ureter adenocarcinoma 9.8 KRT7 KRT5
49 subareolar duct papillomatosis 9.8 KRT7 KRT5
50 bone leiomyosarcoma 9.8 KRT7 KRT5

Graphical network of the top 20 diseases related to Benign Breast Adenomyoepithelioma:



Diseases related to Benign Breast Adenomyoepithelioma

Symptoms & Phenotypes for Benign Breast Adenomyoepithelioma

GenomeRNAi Phenotypes related to Benign Breast Adenomyoepithelioma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-153 9.32 KRT5
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-17 9.32 KRT5
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-58 9.32 EGFR
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-68 9.32 KRT7
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-71 9.32 KRT5 KRT7
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-72 9.32 KRT7
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.32 EGFR KRT5 KRT7

MGI Mouse Phenotypes related to Benign Breast Adenomyoepithelioma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 9.26 EGFR KRT14 KRT5 SFN
2 digestive/alimentary MP:0005381 8.92 EGFR KRT14 KRT5 SFN

Drugs & Therapeutics for Benign Breast Adenomyoepithelioma

Search Clinical Trials , NIH Clinical Center for Benign Breast Adenomyoepithelioma

Genetic Tests for Benign Breast Adenomyoepithelioma

Anatomical Context for Benign Breast Adenomyoepithelioma

MalaCards organs/tissues related to Benign Breast Adenomyoepithelioma:

40
Breast, Lung, Skin, Thymus, Ovary, Bone, Heart

Publications for Benign Breast Adenomyoepithelioma

Articles related to Benign Breast Adenomyoepithelioma:

# Title Authors PMID Year
1
Benign Bilateral Adenomyoepithelioma of the Mammary Gland in a Ring-tailed Lemur (Lemur catta). 61
28942309 2017
2
Imaging features of benign adenomyoepithelioma of the breast. 61
23325754 2013
3
Ultrasonographic features of benign adenomyoepithelioma of the breast. 61
20808695 2010
4
Fine-needle aspiration biopsy of benign adenomyoepithelioma of the breast: radiologic and pathologic correlation in four cases. 61
17924402 2007
5
Benign adenomyoepithelioma of the breast: imaging findings mimicking malignancy and histopathological features. 61
17325921 2007
6
Benign adenomyoepithelioma of the breast: a case with gross mimicking of malignancy. 61
12390363 2002
7
Benign adenomyoepithelioma of the breast. 61
2544054 1989

Variations for Benign Breast Adenomyoepithelioma

Expression for Benign Breast Adenomyoepithelioma

Search GEO for disease gene expression data for Benign Breast Adenomyoepithelioma.

Pathways for Benign Breast Adenomyoepithelioma

Pathways related to Benign Breast Adenomyoepithelioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.83 KRT7 KRT5 KRT14 EGFR
2
Show member pathways
11.79 KRT7 KRT5 KRT14
3 11.38 SFN EGFR
4
Show member pathways
11.17 KRT7 KRT5 KRT14
5 10.75 SFN EGFR
6 10.71 SFN KRT5 KRT14

GO Terms for Benign Breast Adenomyoepithelioma

Cellular components related to Benign Breast Adenomyoepithelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament GO:0005882 9.13 KRT7 KRT5 KRT14
2 keratin filament GO:0045095 8.8 KRT7 KRT5 KRT14

Biological processes related to Benign Breast Adenomyoepithelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cornification GO:0070268 9.33 KRT7 KRT5 KRT14
2 positive regulation of cell growth GO:0030307 9.32 SFN EGFR
3 hemidesmosome assembly GO:0031581 9.26 KRT5 KRT14
4 epidermis development GO:0008544 9.13 KRT5 KRT14 EGFR
5 keratinization GO:0031424 8.92 SFN KRT7 KRT5 KRT14

Molecular functions related to Benign Breast Adenomyoepithelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.62 KRT5 KRT14

Sources for Benign Breast Adenomyoepithelioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....