MCID: BNG014
MIFTS: 25

Benign Breast Adenomyoepithelioma

Categories: Cancer diseases

Aliases & Classifications for Benign Breast Adenomyoepithelioma

MalaCards integrated aliases for Benign Breast Adenomyoepithelioma:

Name: Benign Breast Adenomyoepithelioma 12 15 72
Benign Adenomyoepithelioma of the Breast 12

Classifications:



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Disease Ontology 12 DOID:1641
NCIt 50 C5144
UMLS 72 C1332477

Summaries for Benign Breast Adenomyoepithelioma

Disease Ontology : 12 A breast benign neoplasm that is characterized by dual differentiation into luminal cells and myoepithelial cells.

MalaCards based summary : Benign Breast Adenomyoepithelioma, also known as benign adenomyoepithelioma of the breast, is related to rare tumor and lichen planopilaris. An important gene associated with Benign Breast Adenomyoepithelioma is KRT14 (Keratin 14), and among its related pathways/superpathways are Developmental Biology and Keratinization. Affiliated tissues include breast, and related phenotypes are craniofacial and digestive/alimentary

Related Diseases for Benign Breast Adenomyoepithelioma

Diseases in the Breast Adenomyoepithelioma family:

Benign Breast Adenomyoepithelioma

Diseases related to Benign Breast Adenomyoepithelioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 91)
# Related Disease Score Top Affiliating Genes
1 rare tumor 10.3
2 lichen planopilaris 10.3 KRT5 KRT14
3 epidermolysis bullosa simplex, autosomal recessive 1 10.3 KRT5 KRT14
4 epidermolysis bullosa 10.3 KRT5 KRT14
5 epidermolysis bullosa simplex 10.2 KRT5 KRT14
6 epidermolysis bullosa simplex, localized 10.2 KRT5 KRT14
7 epidermolysis bullosa simplex, generalized 10.2 KRT5 KRT14
8 epidermolysis bullosa simplex with mottled pigmentation 10.2 KRT5 KRT14
9 odontoma 10.2 KRT5 KRT14
10 cervical clear cell adenocarcinoma 10.2 KRT5 KRT14
11 vesiculobullous skin disease 10.2 KRT5 KRT14
12 thoracic benign neoplasm 10.2 KRT5 KRT14
13 breast benign neoplasm 10.2 KRT5 KRT14
14 limbal stem cell deficiency 10.2 SFN KRT14
15 epidermolysis bullosa simplex, dowling-meara type 10.2 KRT5 KRT14
16 spiradenoma 10.2 KRT7 KRT14
17 brooke-spiegler syndrome 10.1 KRT7 KRT14
18 inverted transitional papilloma 10.1 KRT7 KRT5
19 rare breast tumor 10.1
20 ceruminoma 10.1 KRT7 KRT5
21 balloon cell malignant melanoma 10.1 KRT7 KRT5
22 malignant spiradenoma 10.1 KRT7 KRT5
23 benign mesothelioma 10.1 KRT7 KRT5
24 middle ear adenoma 10.1 KRT7 KRT5
25 bile duct mucoepidermoid carcinoma 10.1 KRT7 KRT5
26 sensory organ benign neoplasm 10.1 KRT7 KRT5
27 epithelial-myoepithelial carcinoma 10.1 KRT7 KRT14
28 malignant biphasic mesothelioma 10.1 KRT7 KRT5
29 skin benign neoplasm 10.1 KRT5 KRT14
30 prostate squamous cell carcinoma 10.1 KRT7 KRT5
31 gastric squamous cell carcinoma 10.1 KRT7 KRT5
32 peritoneum cancer 10.1 KRT7 KRT5
33 lymphoepithelioma-like carcinoma 10.1 KRT7 KRT5
34 dowling-degos disease 10.1 KRT5 KRT14
35 nasal cavity squamous cell carcinoma 10.1 KRT7 KRT5
36 cystadenofibroma 10.0 KRT7 KRT5
37 eccrine sweat gland neoplasm 10.0 KRT7 KRT5
38 breast secretory carcinoma 10.0 KRT7 KRT5
39 atypical choroid plexus papilloma 10.0 KRT7 KRT5
40 white sponge nevus 1 10.0 KRT7 KRT14
41 necrotizing sialometaplasia 10.0 KRT7 KRT5
42 anus cancer 10.0 KRT7 KRT5
43 cystitis cystica 10.0 KRT7 KRT5
44 craniopharyngioma 9.9 KRT7 KRT14
45 esophageal basaloid squamous cell carcinoma 9.9 KRT14 EGFR
46 thymus cancer 9.9 KRT7 KRT5
47 pleomorphic carcinoma 9.8 KRT7 EGFR
48 breast carcinoma in situ 9.8 KRT5 EGFR
49 cervical adenosquamous carcinoma 9.7 KRT7 EGFR
50 horseshoe kidney 9.7 KRT7 EGFR

Graphical network of the top 20 diseases related to Benign Breast Adenomyoepithelioma:



Diseases related to Benign Breast Adenomyoepithelioma

Symptoms & Phenotypes for Benign Breast Adenomyoepithelioma

MGI Mouse Phenotypes related to Benign Breast Adenomyoepithelioma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 9.46 EGFR KRT14 KRT5 SFN
2 digestive/alimentary MP:0005381 9.26 EGFR KRT14 KRT5 SFN
3 integument MP:0010771 8.92 EGFR KRT14 KRT5 SFN

Drugs & Therapeutics for Benign Breast Adenomyoepithelioma

Search Clinical Trials , NIH Clinical Center for Benign Breast Adenomyoepithelioma

Genetic Tests for Benign Breast Adenomyoepithelioma

Anatomical Context for Benign Breast Adenomyoepithelioma

MalaCards organs/tissues related to Benign Breast Adenomyoepithelioma:

41
Breast

Publications for Benign Breast Adenomyoepithelioma

Articles related to Benign Breast Adenomyoepithelioma:

# Title Authors PMID Year
1
Benign Bilateral Adenomyoepithelioma of the Mammary Gland in a Ring-tailed Lemur (Lemur catta). 38
28942309 2017
2
Imaging features of benign adenomyoepithelioma of the breast. 38
23325754 2013
3
Ultrasonographic features of benign adenomyoepithelioma of the breast. 38
20808695 2010
4
Fine-needle aspiration biopsy of benign adenomyoepithelioma of the breast: radiologic and pathologic correlation in four cases. 38
17924402 2007
5
Benign adenomyoepithelioma of the breast: imaging findings mimicking malignancy and histopathological features. 38
17325921 2007
6
Benign adenomyoepithelioma of the breast: a case with gross mimicking of malignancy. 38
12390363 2002
7
Benign adenomyoepithelioma of the breast. 38
2544054 1989

Variations for Benign Breast Adenomyoepithelioma

Expression for Benign Breast Adenomyoepithelioma

Search GEO for disease gene expression data for Benign Breast Adenomyoepithelioma.

Pathways for Benign Breast Adenomyoepithelioma

Pathways related to Benign Breast Adenomyoepithelioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.83 KRT7 KRT5 KRT14 EGFR
2
Show member pathways
11.79 KRT7 KRT5 KRT14
3 11.52 SFN EGFR
4 11.38 SFN EGFR
5
Show member pathways
11.17 KRT7 KRT5 KRT14
6 10.75 SFN EGFR
7 10.71 SFN KRT5 KRT14

GO Terms for Benign Breast Adenomyoepithelioma

Cellular components related to Benign Breast Adenomyoepithelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.46 SFN KRT7 KRT5 KRT14
2 intermediate filament GO:0005882 9.13 KRT7 KRT5 KRT14
3 keratin filament GO:0045095 8.8 KRT7 KRT5 KRT14

Biological processes related to Benign Breast Adenomyoepithelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane organization GO:0061024 9.37 SFN EGFR
2 cornification GO:0070268 9.33 KRT7 KRT5 KRT14
3 positive regulation of cell growth GO:0030307 9.32 SFN EGFR
4 hemidesmosome assembly GO:0031581 9.26 KRT5 KRT14
5 epidermis development GO:0008544 9.13 KRT5 KRT14 EGFR
6 keratinization GO:0031424 8.92 SFN KRT7 KRT5 KRT14

Molecular functions related to Benign Breast Adenomyoepithelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.62 KRT5 KRT14

Sources for Benign Breast Adenomyoepithelioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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