MCID: BNG025
MIFTS: 25

Benign Mammary Dysplasia

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Benign Mammary Dysplasia

MalaCards integrated aliases for Benign Mammary Dysplasia:

Name: Benign Mammary Dysplasia 12 73

Classifications:



External Ids:

Disease Ontology 12 DOID:9504
ICD9CM 35 610.8
ICD10 33 N60

Summaries for Benign Mammary Dysplasia

Disease Ontology : 12 A breast benign neoplasm that encompasses a range of conditions in which there is marked change in the breast tissue.

MalaCards based summary : Benign Mammary Dysplasia is related to solitary cyst of breast and breast cyst. An important gene associated with Benign Mammary Dysplasia is BCL2 (BCL2, Apoptosis Regulator), and among its related pathways/superpathways are Endometrial cancer and Pathways in cancer. Affiliated tissues include breast.

Wikipedia : 76 Fibrocystic breast changes is a condition of the breasts were there may be pain, breast cysts, and... more...

Related Diseases for Benign Mammary Dysplasia

Diseases related to Benign Mammary Dysplasia via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 solitary cyst of breast 10.4
2 breast cyst 10.4
3 breast fibroadenosis 10.4
4 fibrosclerosis of breast 10.4
5 breast cancer 9.9
6 lymphoma, non-hodgkin, familial 9.8 BAK1 BCL2
7 cervical cancer 9.7 BAK1 BCL2

Graphical network of the top 20 diseases related to Benign Mammary Dysplasia:



Diseases related to Benign Mammary Dysplasia

Symptoms & Phenotypes for Benign Mammary Dysplasia

Drugs & Therapeutics for Benign Mammary Dysplasia

Search Clinical Trials , NIH Clinical Center for Benign Mammary Dysplasia

Genetic Tests for Benign Mammary Dysplasia

Anatomical Context for Benign Mammary Dysplasia

MalaCards organs/tissues related to Benign Mammary Dysplasia:

41
Breast

Publications for Benign Mammary Dysplasia

Articles related to Benign Mammary Dysplasia:

# Title Authors Year
1
Expression of the apoptotic markers in normal breast epithelium, benign mammary dysplasia and in breast cancer. ( 15478112 )
2004
2
Benign mammary dysplasia. ( 514167 )
1979
3
Modern management of benign mammary dysplasia. ( 470733 )
1979
4
Benign mammary dysplasia. ( 514166 )
1979
5
Aspiration biopsy cytology in proliferating benign mammary dysplasia. ( 277037 )
1978
6
Fibrocystic disease of the breast (benign mammary dysplasia). ( 1165420 )
1975
7
Periductal foam cells in benign mammary dysplasia. ( 1195061 )
1975
8
Neural invasion in benign mammary dysplasia. ( 4719773 )
1973
9
Benign mammary dysplasia. ( 5073961 )
1972

Variations for Benign Mammary Dysplasia

Expression for Benign Mammary Dysplasia

Search GEO for disease gene expression data for Benign Mammary Dysplasia.

Pathways for Benign Mammary Dysplasia

Pathways related to Benign Mammary Dysplasia according to GeneCards Suite gene sharing:

(show all 21)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.34 BAK1 BCL2
2 12.31 BAK1 BCL2
3
Show member pathways
12.29 BAK1 BCL2
4
Show member pathways
12.25 BAK1 BCL2
5
Show member pathways
12.23 BAK1 BCL2
6
Show member pathways
12.16 BAK1 BCL2
7 12.02 BAK1 BCL2
8 11.84 BAK1 BCL2
9 11.79 BAK1 BCL2
10 11.73 BAK1 BCL2
11 11.68 BAK1 BCL2
12 11.6 BAK1 BCL2
13
Show member pathways
11.55 BAK1 BCL2
14 11.49 BAK1 BCL2
15 11.37 BAK1 BCL2
16
Show member pathways
11.29 BAK1 BCL2
17 11.18 BAK1 BCL2
18 10.86 BAK1 BCL2
19
Show member pathways
10.81 BAK1 BCL2
20 10.32 BAK1 BCL2

GO Terms for Benign Mammary Dysplasia

Cellular components related to Benign Mammary Dysplasia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitochondrial outer membrane GO:0005741 9.16 BAK1 BCL2
2 mitochondrial membrane GO:0031966 8.96 BAK1 BCL2
3 pore complex GO:0046930 8.62 BAK1 BCL2

Biological processes related to Benign Mammary Dysplasia according to GeneCards Suite gene sharing:

(show all 17)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of cell proliferation GO:0008285 9.57 BAK1 BCL2
2 cell proliferation GO:0008283 9.56 BAK1 BCL2
3 response to drug GO:0042493 9.55 BAK1 BCL2
4 regulation of apoptotic process GO:0042981 9.54 BAK1 BCL2
5 regulation of cell cycle GO:0051726 9.52 BAK1 BCL2
6 response to hydrogen peroxide GO:0042542 9.51 BAK1 BCL2
7 intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 9.49 BAK1 BCL2
8 extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 9.48 BAK1 BCL2
9 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 9.46 BAK1 BCL2
10 response to gamma radiation GO:0010332 9.43 BAK1 BCL2
11 regulation of mitochondrial membrane potential GO:0051881 9.4 BAK1 BCL2
12 B cell homeostasis GO:0001782 9.37 BAK1 BCL2
13 release of cytochrome c from mitochondria GO:0001836 9.32 BAK1 BCL2
14 endoplasmic reticulum calcium ion homeostasis GO:0032469 9.26 BAK1 BCL2
15 regulation of mitochondrial membrane permeability GO:0046902 9.16 BAK1 BCL2
16 regulation of protein heterodimerization activity GO:0043497 8.96 BAK1 BCL2
17 regulation of protein homodimerization activity GO:0043496 8.62 BAK1 BCL2

Molecular functions related to Benign Mammary Dysplasia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein heterodimerization activity GO:0046982 8.62 BAK1 BCL2

Sources for Benign Mammary Dysplasia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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