MCID: BNG004
MIFTS: 20

Benign Mastocytoma

Categories: Cancer diseases

Aliases & Classifications for Benign Mastocytoma

MalaCards integrated aliases for Benign Mastocytoma:

Name: Benign Mastocytoma 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:4658
NCIt 49 C9303
SNOMED-CT 67 404171008 89796001
ICD10 32 D47.09
UMLS 71 C0024897 C2242987

Summaries for Benign Mastocytoma

MalaCards based summary : Benign Mastocytoma is related to extracutaneous mastocytoma and mast cell neoplasm. An important gene associated with Benign Mastocytoma is CLEC11A (C-Type Lectin Domain Containing 11A), and among its related pathways/superpathways are Akt Signaling and PAK Pathway.

Related Diseases for Benign Mastocytoma

Diseases related to Benign Mastocytoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 64)
# Related Disease Score Top Affiliating Genes
1 extracutaneous mastocytoma 32.0 KIT CD2
2 mast cell neoplasm 32.0 KIT CD2
3 esophagus sarcoma 10.1 NAAA KIT
4 hydrops of gallbladder 10.1 NAAA CD40LG
5 piebald trait 10.1 KIT CLEC11A
6 intussusception 10.0 KIT CD40LG
7 exanthem 10.0 KIT CD40LG
8 mast-cell sarcoma 10.0 KIT CD2
9 sm-ahnmd 10.0 KIT CD2
10 salivary gland disease 9.9 KIT CD40LG
11 isolated growth hormone deficiency type iii 9.9 CD40LG CD2
12 indolent systemic mastocytosis 9.9 KIT CD2
13 testicular disease 9.9 KIT CD40LG
14 systemic mastocytosis 9.9 KIT CD2
15 mastocytosis 9.9 KIT CD2
16 aseptic meningitis 9.9 CD40LG CD2
17 aggressive systemic mastocytosis 9.9 KIT CD2
18 mastocytosis, cutaneous 9.8 KIT CD2
19 small intestinal sarcoma 9.8 PTPRC KIT
20 endometrial small cell carcinoma 9.8 PTPRC KIT
21 small cell carcinoma 9.8 PTPRC KIT
22 glomangiomatosis 9.8 PTPRC KIT
23 mediastinal cancer 9.8 PTPRC KIT
24 conventional fibrosarcoma 9.8 PTPRC KIT
25 retroperitoneum carcinoma 9.8 PTPRC KIT
26 t cell deficiency 9.8 PTPRC CD40LG
27 myeloid sarcoma 9.8 PTPRC KIT
28 monoclonal gammopathy of uncertain significance 9.8 PTPRC CD40LG
29 lymphoplasmacytic lymphoma 9.8 PTPRC CD40LG
30 plasma cell neoplasm 9.8 PTPRC CD40LG
31 thymic carcinoma 9.7 PTPRC KIT
32 lymph node disease 9.7 PTPRC CD40LG
33 reticulum cell sarcoma 9.7 PTPRC CD2
34 angiomyolipoma 9.7 PTPRC KIT
35 blood coagulation disease 9.7 NAAA KIT CD40LG
36 blood platelet disease 9.7 NAAA KIT CD40LG
37 malignant fibrous histiocytoma 9.7 PTPRC KIT
38 merkel cell carcinoma 9.7 PTPRC KIT
39 cutaneous solitary mastocytoma 9.7 KIT CLEC11A CD2
40 mature b-cell neoplasm 9.7 PTPRC CD40LG
41 neuroendocrine carcinoma 9.6 PTPRC KIT
42 autoimmune disease of musculoskeletal system 9.6 PTPRC CD40LG
43 leiomyosarcoma 9.6 PTPRC KIT
44 primary bacterial infectious disease 9.6 PTPRC CD40LG
45 x-linked recessive disease 9.6 PTPRC CD40LG
46 autoimmune hepatitis 9.5 PTPRC CD40LG
47 small cell cancer of the lung 9.5 PTPRC KIT
48 thymus gland disease 9.4 PTPRC KIT CD40LG
49 thymus cancer 9.4 PTPRC KIT CD40LG
50 leukocyte disease 9.4 PTPRC KIT CD40LG

Graphical network of the top 20 diseases related to Benign Mastocytoma:



Diseases related to Benign Mastocytoma

Symptoms & Phenotypes for Benign Mastocytoma

Drugs & Therapeutics for Benign Mastocytoma

Search Clinical Trials , NIH Clinical Center for Benign Mastocytoma

Genetic Tests for Benign Mastocytoma

Anatomical Context for Benign Mastocytoma

Publications for Benign Mastocytoma

Articles related to Benign Mastocytoma:

# Title Authors PMID Year
1
Diagnostic criteria and classification of mastocytosis: a consensus proposal. 61
11377686 2001
2
Tissue mast cells in health and disease. 61
2582403 1985

Variations for Benign Mastocytoma

Expression for Benign Mastocytoma

Search GEO for disease gene expression data for Benign Mastocytoma.

Pathways for Benign Mastocytoma

Pathways related to Benign Mastocytoma according to GeneCards Suite gene sharing:

(show all 12)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.88 KIT CLEC11A CD40LG CD2
2
Show member pathways
12.42 PTPRC KIT CLEC11A CD40LG CD2
3 11.67 PTPRC CD40LG CD2
4 11.51 KIT CD2
5 11.47 PTPRC KIT
6 11.44 PTPRC KIT CD40LG CD2
7 11.4 PTPRC KIT CD2
8 11.38 PTPRC KIT
9 11.33 PTPRC KIT
10 10.98 PTPRC CD40LG
11 10.87 PTPRC CD40LG
12 10.46 KIT CLEC11A CD40LG CD2

GO Terms for Benign Mastocytoma

Cellular components related to Benign Mastocytoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 9.56 PTPRC KIT CD40LG CD2
2 cell surface GO:0009986 9.46 PTPRC KIT CD40LG CD2
3 external side of plasma membrane GO:0009897 9.26 PTPRC KIT CD40LG CD2
4 cytoplasmic side of plasma membrane GO:0009898 8.8 PTPRC KIT CD2

Biological processes related to Benign Mastocytoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hematopoietic progenitor cell differentiation GO:0002244 9.46 PTPRC KIT
2 positive regulation of T cell proliferation GO:0042102 9.43 PTPRC CD40LG
3 positive regulation of tumor necrosis factor production GO:0032760 9.4 PTPRC CD2
4 T cell activation GO:0042110 9.37 PTPRC CD2
5 T cell differentiation GO:0030217 9.32 PTPRC KIT
6 B cell proliferation GO:0042100 9.26 PTPRC CD40LG
7 leukocyte cell-cell adhesion GO:0007159 9.16 PTPRC CD40LG
8 heterotypic cell-cell adhesion GO:0034113 8.96 PTPRC CD2
9 B cell differentiation GO:0030183 8.8 PTPRC KIT CD40LG

Sources for Benign Mastocytoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....