MCID: BNG041
MIFTS: 32

Benign Metastasizing Leiomyoma

Categories: Cancer diseases, Rare diseases

Aliases & Classifications for Benign Metastasizing Leiomyoma

MalaCards integrated aliases for Benign Metastasizing Leiomyoma:

Name: Benign Metastasizing Leiomyoma 54
Benign Metastasizing Leiomyoma of Uterus 74

Classifications:



External Ids:

UMLS 74 C0346201

Summaries for Benign Metastasizing Leiomyoma

MalaCards based summary : Benign Metastasizing Leiomyoma, also known as benign metastasizing leiomyoma of uterus, is related to leiomyoma and leiomyomatosis. An important gene associated with Benign Metastasizing Leiomyoma is DES (Desmin), and among its related pathways/superpathways are MicroRNAs in cancer and Cytoskeletal Signaling. Affiliated tissues include lung, breast and uterus, and related phenotypes are cardiovascular system and cellular

Related Diseases for Benign Metastasizing Leiomyoma

Diseases related to Benign Metastasizing Leiomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 170)
# Related Disease Score Top Affiliating Genes
1 leiomyoma 30.8 ACTC1 CYP19A1 DES PGR VIM
2 leiomyomatosis 10.4
3 intravenous leiomyomatosis 10.4
4 ovarian fibrothecoma 10.3 ACTC1 DES
5 fibroblastic rheumatism 10.3 ACTC1 DES
6 cutaneous leiomyosarcoma 10.3 ACTC1 DES
7 botryoid rhabdomyosarcoma 10.3 ACTC1 DES
8 glomangioma 10.3 ACTC1 DES
9 adenosarcoma 10.3 DES PGR
10 calcifying aponeurotic fibroma 10.3 ACTC1 PGR
11 bizarre leiomyoma 10.3 ACTC1 PGR
12 myxoid leiomyosarcoma 10.3 ACTC1 PGR
13 cervical carcinosarcoma 10.3 BCL2 PGR
14 non-langerhans-cell histiocytosis 10.3 ACTC1 DES
15 pulmonary vein stenosis 10.3 ACTC1 DES
16 ovarian benign neoplasm 10.3 CYP19A1 DES
17 ischemic fasciitis 10.3 ACTC1 DES
18 fasciitis 10.3 ACTC1 DES
19 leiomyoma, uterine 10.3
20 progesterone-receptor positive breast cancer 10.3 CYP19A1 PGR
21 dedifferentiated liposarcoma 10.3 ACTC1 DES
22 gender identity disorder 10.3 CYP19A1 PGR
23 cystadenoma 10.3 KRT7 PGR
24 estrogen excess 10.3 CYP19A1 PGR
25 lung leiomyoma 10.3 MIR221 PGR
26 eccrine papillary adenocarcinoma 10.3 KRT7 PGR
27 mammographic density 10.3 CYP19A1 PGR
28 endosalpingiosis 10.2 KRT7 PGR
29 endometrial stromal nodule 10.2 CYP19A1 PGR
30 oncocytic breast carcinoma 10.2 KRT7 PGR
31 horner's syndrome 10.2 DES KRT7
32 chickenpox 10.2 ACTC1 PGR
33 endometriosis of ovary 10.2 CYP19A1 PGR
34 cribriform carcinoma 10.2 KRT7 PGR
35 adenoid basal cell carcinoma 10.2 KRT7 PGR
36 pancreatic serous cystadenoma 10.2 KRT7 PGR
37 corneal abscess 10.2 KRT7 PGR
38 papillary serous adenocarcinoma 10.2 KRT7 PGR
39 muscle cancer 10.2 DES PGR
40 female reproductive endometrioid cancer 10.2 KRT7 PGR
41 infantile digital fibromatosis 10.2 DES VIM
42 primitive neuroectodermal tumor of the cervix uteri 10.2 DES VIM
43 cervical adenocarcinoma 10.2 KRT7 PGR
44 sertoli-leydig cell tumor 10.2 KRT7 PGR
45 prostatic hypertrophy 10.2 CYP19A1 PGR
46 sclerosing hemangioma 10.2 KRT7 PGR
47 biphasic synovial sarcoma 10.2 DES VIM
48 spiradenoma 10.2 ACTC1 KRT7
49 cystadenocarcinoma 10.2 KRT7 PGR
50 reproductive organ benign neoplasm 10.2 CYP19A1 PGR

Graphical network of the top 20 diseases related to Benign Metastasizing Leiomyoma:



Diseases related to Benign Metastasizing Leiomyoma

Symptoms & Phenotypes for Benign Metastasizing Leiomyoma

MGI Mouse Phenotypes related to Benign Metastasizing Leiomyoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.73 ACTC1 BCL2 CYP19A1 DES PGR VIM
2 cellular MP:0005384 9.7 ACTC1 BCL2 CYP19A1 DES KRT7 PGR
3 homeostasis/metabolism MP:0005376 9.56 ACTC1 BCL2 CYP19A1 DES KRT7 LGALS1
4 muscle MP:0005369 9.17 ACTC1 BCL2 CYP19A1 DES LGALS1 PGR

Drugs & Therapeutics for Benign Metastasizing Leiomyoma

Search Clinical Trials , NIH Clinical Center for Benign Metastasizing Leiomyoma

Genetic Tests for Benign Metastasizing Leiomyoma

Anatomical Context for Benign Metastasizing Leiomyoma

MalaCards organs/tissues related to Benign Metastasizing Leiomyoma:

42
Lung, Breast, Uterus, Ovary, Kidney, Bone, Lymph Node

Publications for Benign Metastasizing Leiomyoma

Articles related to Benign Metastasizing Leiomyoma:

(show top 50) (show all 127)
# Title Authors Year
1
Benign metastasizing leiomyoma presenting with miliary pattern and fatal outcome: Case report with molecular analysis & review of the literature. ( 30989050 )
2019
2
Benign Metastasizing Leiomyoma to the Lung and Spine: A Case Report and Literature Review. ( 31011319 )
2019
3
Multisystemic Benign Metastasizing Leiomyoma: An Unusual Condition with an Atypical Clinical Presentation. ( 31093407 )
2019
4
Concurrent pulmonary benign metastasizing leiomyoma and primary lung adenocarcinoma: a case report. ( 30264014 )
2018
5
Deep sequencing reveals the molecular pathology characteristics between primary uterine leiomyoma and pulmonary benign metastasizing leiomyoma. ( 29484624 )
2018
6
Pelvic and pulmonary benign metastasizing leiomyoma: A case report. ( 29785389 )
2018
7
The Heart as a Site of Metastasis of Benign Metastasizing Leiomyoma: Case Report and Review of the Literature. ( 29951323 )
2018
8
Pulmonary benign metastasizing leiomyoma: A case report. ( 29977777 )
2018
9
Concurrent benign metastasizing leiomyoma in the lung and lumbar spine with elevated standardized uptake value level in positron-emission tomography computed tomography: A case report and literature review. ( 29979408 )
2018
10
Case of pulmonary benign metastasizing leiomyoma from synchronous uterine leiomyoma in a postmenopausal woman. ( 30225333 )
2018
11
Benign Metastasizing Leiomyoma of the Uterus: Rare Manifestation of a Frequent Pathology. ( 30510824 )
2018
12
Benign Metastasizing Leiomyoma. ( 27659239 )
2017
13
Pulmonary benign metastasizing leiomyoma presented as acute respiratory distress. ( 28116091 )
2017
14
Malignant Transformation of Pulmonary Benign Metastasizing Leiomyoma. ( 28180107 )
2017
15
Benign metastasizing leiomyoma: A review of current literature in respect to the time and type of previous gynecological surgery. ( 28426767 )
2017
16
Massively parallel sequencing and genome-wide copy number analysis revealed a clonal relationship in benign metastasizing leiomyoma. ( 28533481 )
2017
17
Benign metastasizing leiomyoma presenting as multiple cystic pulmonary nodules: a case report. ( 28899426 )
2017
18
Benign metastasizing leiomyoma and 18-FDG-PET/CT: A case report and literature review. ( 28927125 )
2017
19
Recurrent Pneumothoraces in a Patient With Pulmonary Benign Metastasizing Leiomyoma. ( 29026364 )
2017
20
Benign metastasizing leiomyoma of bone and lung in postmenopausal women: two rare case reports and review of the literature. ( 29767878 )
2017
21
Pulmonary benign metastasizing leiomyoma, a rare cause of pulmonary nodules. ( 26518660 )
2016
22
A rare cause of miliary pattern and respiratory failure - Benign metastasizing leiomyoma. ( 27178355 )
2016
23
Benign Metastasizing Leiomyoma. ( 27514603 )
2016
24
Benign metastasizing leiomyoma in triple location: lungs, parametria and appendix. ( 27582687 )
2016
25
Treatment decision based on the biological behavior of pulmonary benign metastasizing leiomyoma. ( 27621897 )
2016
26
Cystic Benign Metastasizing Leiomyoma of the Lung Mimicking Hydatid Cyst. ( 27631636 )
2016
27
A case report of benign metastasizing leiomyoma of the lung: FDG-PET-CT findings and the utility of uterine needle biopsy. ( 29894087 )
2016
28
What are MRI findings of Spine Benign Metastasizing Leiomyoma? Case report with literature review. ( 25632838 )
2015
29
Pulmonary benign metastasizing leiomyoma from the uterine leiomyoma: a case report. ( 25774240 )
2015
30
Benign metastasizing leiomyoma of the cervical spine 31 years after uterine leiomyoma resection. ( 25953612 )
2015
31
Benign metastasizing leiomyoma of the lung: A case report and literature review. ( 26171020 )
2015
32
Incidental Finding of Synchronous, Benign, Metastasizing Leiomyoma with Distinct Cytogenetics in the Lung and Uterus. ( 26244194 )
2015
33
Iatrogenic exacerbation of pulmonary arteriovenous malformation in a patient with benign metastasizing leiomyoma. ( 25473552 )
2014
34
Benign metastasizing leiomyoma. Case report and review of the literature. ( 23903362 )
2014
35
Benign metastasizing leiomyoma presenting as cavitating lung nodules. ( 24255161 )
2014
36
Difficulty in complete transarterial embolization for pulmonary benign metastasizing leiomyoma with massive hemoptysis. ( 24272622 )
2014
37
Pulmonary Benign Metastasizing Leiomyoma: An Extremely Rare Case. ( 24715553 )
2014
38
Benign metastasizing leiomyoma: a rare type of lung metastases-two case reports and review of the literature. ( 24716049 )
2014
39
Solitary benign metastasizing leiomyoma: imaging features and pathological findings. ( 24831406 )
2014
40
Pulmonary benign metastasizing leiomyoma: a case report and literature review. ( 24977035 )
2014
41
Case of concurrent benign metastasizing leiomyoma in the lung and retroperitoneum, with a focus on its etiology. ( 25131768 )
2014
42
Incidental benign metastasizing leiomyoma in a patient with bone sarcoma: a case report. ( 25221682 )
2014
43
Pulmonary benign metastasizing leiomyoma: a case report. ( 25400799 )
2014
44
A rare pancreatic tumor in a 52-year-old Chinese woman. Pancreatic benign metastasizing leiomyoma. ( 23333466 )
2013
45
Elevated 99mTc 3PRGD2 activity in benign metastasizing leiomyoma. ( 23334126 )
2013
46
Novel hormone treatment of benign metastasizing leiomyoma: an analysis of five cases and literature review. ( 23465706 )
2013
47
An undescribed coexistence of benign metastasizing leiomyoma in the lung with serous borderline tumor of the ovary. ( 23781598 )
2013
48
Pulmonary benign metastasizing leiomyoma from uterine leiomyoma. ( 23866077 )
2013
49
Successful treatment of benign metastasizing leiomyoma with oral alternated chemotherapeutic agents. ( 24065503 )
2013
50
Benign metastasizing leiomyoma of the lung. ( 24134076 )
2013

Variations for Benign Metastasizing Leiomyoma

Expression for Benign Metastasizing Leiomyoma

Search GEO for disease gene expression data for Benign Metastasizing Leiomyoma.

Pathways for Benign Metastasizing Leiomyoma

Pathways related to Benign Metastasizing Leiomyoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 12.02 BCL2 MIR221 VIM
2 11.75 ACTC1 DES KRT7 VIM
3
Show member pathways
11.37 DES KRT7 VIM
4
Show member pathways
10.97 DES VIM
5 10.76 CYP19A1 PGR
6 10.66 ACTC1 DES VIM

GO Terms for Benign Metastasizing Leiomyoma

Cellular components related to Benign Metastasizing Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament GO:0005882 8.8 DES KRT7 VIM

Biological processes related to Benign Metastasizing Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to drug GO:0042493 9.43 ACTC1 BCL2 LGALS1
2 mammary gland development GO:0030879 9.16 CYP19A1 PGR
3 intermediate filament organization GO:0045109 8.96 DES VIM
4 muscle filament sliding GO:0030049 8.8 ACTC1 DES VIM

Sources for Benign Metastasizing Leiomyoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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