MCID: BNG041
MIFTS: 33

Benign Metastasizing Leiomyoma

Categories: Rare diseases, Cancer diseases

Aliases & Classifications for Benign Metastasizing Leiomyoma

MalaCards integrated aliases for Benign Metastasizing Leiomyoma:

Name: Benign Metastasizing Leiomyoma 53
Benign Metastasizing Leiomyoma of Uterus 73

Classifications:



External Ids:

UMLS 73 C0346201

Summaries for Benign Metastasizing Leiomyoma

MalaCards based summary : Benign Metastasizing Leiomyoma, also known as benign metastasizing leiomyoma of uterus, is related to leiomyoma and pneumothorax. An important gene associated with Benign Metastasizing Leiomyoma is DES (Desmin), and among its related pathways/superpathways are MicroRNAs in cancer and Cytoskeletal Signaling. Affiliated tissues include uterus, lung and bone, and related phenotypes are cardiovascular system and cellular

Related Diseases for Benign Metastasizing Leiomyoma

Diseases related to Benign Metastasizing Leiomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 166)
# Related Disease Score Top Affiliating Genes
1 leiomyoma 30.3 ACTC1 CYP19A1 DES PGR VIM
2 pneumothorax 30.0 PGR VIM
3 ovarian fibrothecoma 10.7 ACTC1 DES
4 progesterone-receptor positive breast cancer 10.7 CYP19A1 PGR
5 fibroblastic rheumatism 10.7 ACTC1 DES
6 cutaneous leiomyosarcoma 10.7 ACTC1 DES
7 botryoid rhabdomyosarcoma 10.7 ACTC1 DES
8 adenosarcoma 10.7 DES PGR
9 gender identity disorder 10.7 CYP19A1 PGR
10 calcifying aponeurotic fibroma 10.7 ACTC1 PGR
11 bizarre leiomyoma 10.6 ACTC1 PGR
12 myxoid leiomyosarcoma 10.6 ACTC1 PGR
13 estrogen excess 10.6 CYP19A1 PGR
14 pulmonary vein stenosis 10.6 ACTC1 DES
15 infantile digital fibromatosis 10.6 DES VIM
16 mammographic density 10.6 CYP19A1 PGR
17 primitive neuroectodermal tumor of the cervix uteri 10.6 DES VIM
18 ischemic fasciitis 10.6 ACTC1 DES
19 endometrial stromal nodule 10.6 CYP19A1 PGR
20 dedifferentiated liposarcoma 10.6 ACTC1 DES
21 endometriosis of ovary 10.6 CYP19A1 PGR
22 biphasic synovial sarcoma 10.6 DES VIM
23 benign breast phyllodes tumor 10.6 PGR VIM
24 syringoma 10.6 DES VIM
25 non-langerhans-cell histiocytosis 10.6 ACTC1 DES
26 endometrial mucinous adenocarcinoma 10.6 PGR VIM
27 juvenile xanthogranuloma 10.6 DES VIM
28 desmoplastic small round cell tumor 10.6 DES VIM
29 mesenchymal chondrosarcoma 10.5 DES VIM
30 lymphangiectasis 10.5 ACTC1 VIM
31 chickenpox 10.5 ACTC1 PGR
32 ovarian benign neoplasm 10.5 DES KRT7
33 prostatic hypertrophy 10.5 CYP19A1 PGR
34 extraskeletal ewing sarcoma 10.5 DES VIM
35 lung leiomyoma 10.5 MIR221 PGR
36 glomangiomyoma 10.5 ACTC1 VIM
37 intravascular papillary endothelial hyperplasia 10.5 ACTC1 VIM
38 endosalpingiosis 10.5 KRT7 PGR
39 uterine sarcoma 10.5 CYP19A1 DES
40 horner's syndrome 10.5 DES KRT7
41 female reproductive endometrioid cancer 10.5 KRT7 PGR
42 granular cell tumor 10.5 DES VIM
43 cribriform carcinoma 10.5 KRT7 PGR
44 oncocytic breast carcinoma 10.5 KRT7 PGR
45 adenoid basal cell carcinoma 10.5 KRT7 PGR
46 apocrine adenocarcinoma 10.5 KRT7 PGR
47 adenofibroma 10.5 ACTC1 VIM
48 pancreatic serous cystadenoma 10.5 KRT7 PGR
49 embryonal sarcoma 10.5 DES VIM
50 corneal abscess 10.5 KRT7 PGR

Graphical network of the top 20 diseases related to Benign Metastasizing Leiomyoma:



Diseases related to Benign Metastasizing Leiomyoma

Symptoms & Phenotypes for Benign Metastasizing Leiomyoma

MGI Mouse Phenotypes related to Benign Metastasizing Leiomyoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.73 PGR VIM ACTC1 BCL2 CYP19A1 DES
2 cellular MP:0005384 9.7 PGR VIM ACTC1 BCL2 CYP19A1 DES
3 homeostasis/metabolism MP:0005376 9.56 PGR VIM ACTC1 BCL2 CYP19A1 DES
4 muscle MP:0005369 9.17 PGR VIM ACTC1 BCL2 CYP19A1 DES

Drugs & Therapeutics for Benign Metastasizing Leiomyoma

Search Clinical Trials , NIH Clinical Center for Benign Metastasizing Leiomyoma

Genetic Tests for Benign Metastasizing Leiomyoma

Anatomical Context for Benign Metastasizing Leiomyoma

MalaCards organs/tissues related to Benign Metastasizing Leiomyoma:

41
Uterus, Lung, Bone, Ovary, Lymph Node, Breast, Spinal Cord

Publications for Benign Metastasizing Leiomyoma

Articles related to Benign Metastasizing Leiomyoma:

(show top 50) (show all 120)
# Title Authors Year
1
Deep sequencing reveals the molecular pathology characteristics between primary uterine leiomyoma and pulmonary benign metastasizing leiomyoma. ( 29484624 )
2018
2
Pelvic and pulmonary benign metastasizing leiomyoma: A case report. ( 29785389 )
2018
3
The Heart as a Site of Metastasis of Benign Metastasizing Leiomyoma: Case Report and Review of the Literature. ( 29951323 )
2018
4
Pulmonary benign metastasizing leiomyoma: A case report. ( 29977777 )
2018
5
Concurrent benign metastasizing leiomyoma in the lung and lumbar spine with elevated standardized uptake value level in positron-emission tomography computed tomography: A case report and literature review. ( 29979408 )
2018
6
Recurrent Pneumothoraces in a Patient With Pulmonary Benign Metastasizing Leiomyoma. ( 29026364 )
2017
7
Benign metastasizing leiomyoma of bone and lung in postmenopausal women: two rare case reports and review of the literature. ( 29767878 )
2017
8
Malignant Transformation of Pulmonary Benign Metastasizing Leiomyoma. ( 28180107 )
2017
9
Benign metastasizing leiomyoma presenting as multiple cystic pulmonary nodules: a case report. ( 28899426 )
2017
10
A Case of Simultaneous Benign Metastasizing Leiomyomas and Disseminated Peritoneal Leiomyomatosis Following Endoscopic Power Morcellation for Uterine Disease. ( 27748666 )
2017
11
Benign metastasizing leiomyoma: A review of current literature in respect to the time and type of previous gynecological surgery. ( 28426767 )
2017
12
Massively parallel sequencing and genome-wide copy number analysis revealed a clonal relationship in benign metastasizing leiomyoma. ( 28533481 )
2017
13
Benign metastasizing leiomyoma and 18-FDG-PET/CT: A case report and literature review. ( 28927125 )
2017
14
Pulmonary benign metastasizing leiomyoma presented as acute respiratory distress. ( 28116091 )
2017
15
Benign Metastasizing Leiomyoma. ( 27514603 )
2016
16
Treatment decision based on the biological behavior of pulmonary benign metastasizing leiomyoma. ( 27621897 )
2016
17
Cystic Benign Metastasizing Leiomyoma of the Lung Mimicking Hydatid Cyst. ( 27631636 )
2016
18
A case report of benign metastasizing leiomyoma of the lung: FDG-PET-CT findings and the utility of uterine needle biopsy. ( 29894087 )
2016
19
A rare cause of miliary pattern and respiratory failure - Benign metastasizing leiomyoma. ( 27178355 )
2016
20
Benign Metastasizing Leiomyoma. ( 27659239 )
2016
21
Benign metastasizing leiomyoma in triple location: lungs, parametria and appendix. ( 27582687 )
2016
22
What are MRI findings of Spine Benign Metastasizing Leiomyoma? Case report with literature review. ( 25632838 )
2015
23
Incidental Finding of Synchronous, Benign, Metastasizing Leiomyoma with Distinct Cytogenetics in the Lung and Uterus. ( 26244194 )
2015
24
Pulmonary benign metastasizing leiomyoma, a rare cause of pulmonary nodules. ( 26518660 )
2015
25
Pulmonary benign metastasizing leiomyoma from the uterine leiomyoma: a case report. ( 25774240 )
2015
26
Benign metastasizing leiomyoma of the cervical spine 31 years after uterine leiomyoma resection. ( 25953612 )
2015
27
Benign metastasizing leiomyoma of the lung: A case report and literature review. ( 26171020 )
2015
28
Incidental benign metastasizing leiomyoma in a patient with bone sarcoma: a case report. ( 25221682 )
2014
29
Pulmonary Benign Metastasizing Leiomyoma: An Extremely Rare Case. ( 24715553 )
2014
30
Pulmonary benign metastasizing leiomyoma: a case report and literature review. ( 24977035 )
2014
31
Benign metastasizing leiomyoma: a rare type of lung metastases-two case reports and review of the literature. ( 24716049 )
2014
32
Iatrogenic exacerbation of pulmonary arteriovenous malformation in a patient with benign metastasizing leiomyoma. ( 25473552 )
2014
33
Solitary benign metastasizing leiomyoma: imaging features and pathological findings. ( 24831406 )
2014
34
Difficulty in complete transarterial embolization for pulmonary benign metastasizing leiomyoma with massive hemoptysis. ( 24272622 )
2014
35
Case of concurrent benign metastasizing leiomyoma in the lung and retroperitoneum, with a focus on its etiology. ( 25131768 )
2014
36
Pulmonary benign metastasizing leiomyoma: a case report. ( 25400799 )
2014
37
Successful treatment of benign metastasizing leiomyoma with oral alternated chemotherapeutic agents. ( 24065503 )
2013
38
Elevated 99mTc 3PRGD2 activity in benign metastasizing leiomyoma. ( 23334126 )
2013
39
Benign metastasizing leiomyoma : Case report and review of the literature. ( 23903362 )
2013
40
Novel hormone treatment of benign metastasizing leiomyoma: an analysis of five cases and literature review. ( 23465706 )
2013
41
A rare pancreatic tumor in a 52-year-old Chinese woman. Pancreatic benign metastasizing leiomyoma. ( 23333466 )
2013
42
Pulmonary benign metastasizing leiomyoma from uterine leiomyoma. ( 23866077 )
2013
43
An undescribed coexistence of benign metastasizing leiomyoma in the lung with serous borderline tumor of the ovary. ( 23781598 )
2013
44
Benign metastasizing leiomyoma of the lung. ( 24134076 )
2013
45
Benign metastasizing leiomyoma of the lung with spontaneous pneumothorax. ( 25360407 )
2013
46
Pulmonary benign metastasizing leiomyoma: report of three cases. ( 24139514 )
2013
47
Benign metastasizing leiomyoma of the lung: report of a case. ( 23117336 )
2013
48
FDG-PET/CT finding of benign metastasizing leiomyoma of the lung. ( 23986835 )
2012
49
Multifocal osteolytic lesions within lumbar spine in a middle-aged Chinese woman: a benign metastasizing leiomyoma? ( 21857396 )
2012
50
Benign metastasizing leiomyoma of the lung. ( 21959195 )
2012

Variations for Benign Metastasizing Leiomyoma

Expression for Benign Metastasizing Leiomyoma

Search GEO for disease gene expression data for Benign Metastasizing Leiomyoma.

Pathways for Benign Metastasizing Leiomyoma

Pathways related to Benign Metastasizing Leiomyoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 12.02 BCL2 MIR221 VIM
2 11.75 ACTC1 DES KRT7 VIM
3
Show member pathways
11.37 DES KRT7 VIM
4
Show member pathways
10.97 DES VIM
5 10.76 CYP19A1 PGR
6 10.66 ACTC1 DES VIM

GO Terms for Benign Metastasizing Leiomyoma

Cellular components related to Benign Metastasizing Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament GO:0005882 8.8 DES KRT7 VIM

Biological processes related to Benign Metastasizing Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to drug GO:0042493 9.43 ACTC1 BCL2 LGALS1
2 mammary gland development GO:0030879 9.16 CYP19A1 PGR
3 intermediate filament organization GO:0045109 8.96 DES VIM
4 muscle filament sliding GO:0030049 8.8 ACTC1 DES VIM

Sources for Benign Metastasizing Leiomyoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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