MCID: BNG033
MIFTS: 28

Benign Perivascular Tumor

Categories: Cancer diseases

Aliases & Classifications for Benign Perivascular Tumor

MalaCards integrated aliases for Benign Perivascular Tumor:

Name: Benign Perivascular Tumor 12 15
Benign Pericytic Neoplasm 74

Classifications:



External Ids:

Disease Ontology 12 DOID:5238
NCIt 51 C6529
UMLS 74 C1332532

Summaries for Benign Perivascular Tumor

MalaCards based summary : Benign Perivascular Tumor, also known as benign pericytic neoplasm, is related to glomangiomatosis and human venous malformation. An important gene associated with Benign Perivascular Tumor is GLMN (Glomulin, FKBP Associated Protein), and among its related pathways/superpathways are Pathways in cancer and NF-kappaB Signaling. Affiliated tissues include breast, lung and prostate, and related phenotypes are cardiovascular system and cellular

Related Diseases for Benign Perivascular Tumor

Diseases related to Benign Perivascular Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 87)
# Related Disease Score Top Affiliating Genes
1 glomangiomatosis 11.2
2 human venous malformation 10.5 GLMN TEK
3 breast rhabdomyosarcoma 10.4 KIDINS220 MB
4 familial glomangioma 10.4 FGF2 GLMN
5 proliferative fasciitis 10.4 MB STAT6
6 ceruminoma 10.4 KIT SLC2A1
7 glomangioma 10.4 GLMN TEK TRPV1
8 choriocarcinoma of ovary 10.3 ENO2 TEK
9 cutaneous ganglioneuroma 10.3 ENO2 KIT
10 orbital cancer 10.3 ENO2 MB
11 gastric leiomyosarcoma 10.3 ENO2 KIT
12 kidney rhabdoid cancer 10.3 ENO2 MB
13 endometrial small cell carcinoma 10.3 ENO2 KIT
14 chronic myocardial ischemia 10.3 FGF2 TEK
15 bronchial disease 10.3 STAT6 TAC1 TRPV1
16 glomangiosarcoma 10.2 KANTR TAC1
17 gallbladder leiomyoma 10.2 CD34 KIT
18 lung leiomyosarcoma 10.2 CD34 KIT
19 ovarian melanoma 10.2 CALD1 KIT
20 pulmonary vein stenosis 10.2 KIT PECAM1
21 liver leiomyoma 10.2 CD34 KIT
22 mixed cell type cancer 10.2 ENO2 KIT MB
23 angiosarcoma 10.2 KIT PECAM1 TEK
24 rhabdomyosarcoma 2 10.2 ENO2 KIDINS220 MB
25 leiomyosarcoma 10.2 ENO2 KIT MB
26 capillary hemangioma 10.2 PECAM1 SLC2A1 TEK
27 extracutaneous mastocytoma 10.2 CD34 KIT
28 rete testis adenocarcinoma 10.2 ENO2 KIT
29 small intestine leiomyosarcoma 10.2 CD34 KIT
30 small intestinal sarcoma 10.2 CD34 KIT
31 gallbladder sarcoma 10.2 CD34 KIT
32 prostate leiomyosarcoma 10.2 CD34 KIT
33 neuroma 10.2 ENO2 FGF2 TRPV1
34 dental abscess 10.2 KANTR KIT
35 meninges sarcoma 10.2 CD34 MB
36 juvenile nasopharyngeal angiofibroma 10.1 FGF2 KIT PECAM1
37 anismus 10.1 KANTR TAC1
38 lung meningioma 10.1 CD34 ENO2
39 malignant mesenchymoma 10.1 CALD1 KIT MB
40 leiomyoma cutis 10.1 CALD1 TAC1 TRPV1
41 arteries, anomalies of 10.1 KANTR MB TRPV1
42 deep angioma 10.1 CD34 SLC2A1
43 mixed liposarcoma 10.1 CD34 MB
44 ecthyma 10.1 FGF2 KANTR STAT6
45 sclerosing liposarcoma 10.1 CD34 MB STAT6
46 intramuscular hemangioma 10.1 CD34 SLC2A1 TEK
47 mechanical ectropion 10.1 CD34 KANTR
48 breast myofibroblastoma 10.1 CALD1 CD34
49 peripheral nervous system disease 10.1 KANTR TAC1 TRPV1
50 kaposiform hemangioendothelioma 10.1 CD34 PECAM1

Graphical network of the top 20 diseases related to Benign Perivascular Tumor:



Diseases related to Benign Perivascular Tumor

Symptoms & Phenotypes for Benign Perivascular Tumor

MGI Mouse Phenotypes related to Benign Perivascular Tumor:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.06 FGF2 FGF23 GLMN KIDINS220 KIT MB
2 cellular MP:0005384 10 CD34 ENO2 FGF2 GLMN KIDINS220 KIT
3 growth/size/body region MP:0005378 9.9 ENO2 FGF23 GLMN KIDINS220 KIT MB
4 homeostasis/metabolism MP:0005376 9.73 CD34 FGF2 FGF23 GLMN KIT MB
5 respiratory system MP:0005388 9.17 ENO2 FGF23 KIT MB PDPN PECAM1

Drugs & Therapeutics for Benign Perivascular Tumor

Search Clinical Trials , NIH Clinical Center for Benign Perivascular Tumor

Genetic Tests for Benign Perivascular Tumor

Anatomical Context for Benign Perivascular Tumor

MalaCards organs/tissues related to Benign Perivascular Tumor:

42
Breast, Lung, Prostate, Small Intestine, Kidney, Bone, Bone Marrow

Publications for Benign Perivascular Tumor

Variations for Benign Perivascular Tumor

Expression for Benign Perivascular Tumor

Search GEO for disease gene expression data for Benign Perivascular Tumor.

Pathways for Benign Perivascular Tumor

Pathways related to Benign Perivascular Tumor according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 12.08 FGF2 FGF23 KIT SLC2A1 STAT6
2 12.07 CD34 KIT PECAM1 STAT6
3 11.33 ENO2 SLC2A1 TEK
4 10.87 FGF2 PDPN PECAM1 TEK

GO Terms for Benign Perivascular Tumor

Cellular components related to Benign Perivascular Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 9.46 CD34 KIT PECAM1 TRPV1
2 apical plasma membrane GO:0016324 9.26 CD34 PDPN SLC2A1 TEK
3 membrane raft GO:0045121 9.02 PDPN PECAM1 SLC2A1 STAT6 TEK

Biological processes related to Benign Perivascular Tumor according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.76 FGF2 FGF23 KIT TEK
2 MAPK cascade GO:0000165 9.71 FGF2 FGF23 KIT TEK
3 positive regulation of protein kinase B signaling GO:0051897 9.56 FGF2 FGF23 KIT TEK
4 response to pain GO:0048265 9.51 TAC1 TRPV1
5 endothelial cell proliferation GO:0001935 9.49 CD34 TEK
6 positive regulation of phospholipase C activity GO:0010863 9.48 FGF2 KIT
7 stem cell proliferation GO:0072089 9.43 CD34 FGF2
8 paracrine signaling GO:0038001 9.37 CD34 FGF2
9 cellular response to nerve growth factor stimulus GO:1990090 9.33 KIDINS220 TAC1 TRPV1
10 peptidyl-tyrosine phosphorylation GO:0018108 9.32 KIT TEK
11 glomerular endothelium development GO:0072011 8.96 CD34 PECAM1
12 positive regulation of phosphatidylinositol 3-kinase activity GO:0043552 8.8 FGF2 KIT TEK

Molecular functions related to Benign Perivascular Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein tyrosine kinase activity GO:0004713 8.62 KIT TEK

Sources for Benign Perivascular Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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