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MCID: BNG022
MIFTS: 27

Benign Pleural Mesothelioma

Categories: Cancer diseases, Respiratory diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Benign Pleural Mesothelioma

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MalaCards integrated aliases for Benign Pleural Mesothelioma:

Name: Benign Pleural Mesothelioma 12 15
Mesothelioma of Pleura 12 32
Benign Neoplasm of Mesothelial Tissue of Pleura 71

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Respiratory diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:5157
NCIt 49 C9351
ICD10 32 C45.0 D19.0
UMLS 71 C0346112 C1377913
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Summaries for Benign Pleural Mesothelioma

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MalaCards based summary : Benign Pleural Mesothelioma, also known as mesothelioma of pleura, is related to malignant pleural mesothelioma and benign mesothelioma. An important gene associated with Benign Pleural Mesothelioma is RRAD (RRAD, Ras Related Glycolysis Inhibitor And Calcium Channel Regulator), and among its related pathways/superpathways are Senescence and Autophagy in Cancer and FOXA2 and FOXA3 transcription factor networks. Affiliated tissues include lymph node, lung and brain, and related phenotype is renal/urinary system.

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Related Diseases for Benign Pleural Mesothelioma

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Diseases in the Benign Pleural Mesothelioma family:

Malignant Pleural Mesothelioma

Diseases related to Benign Pleural Mesothelioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 46)
# Related Disease Score Top Affiliating Genes
1 malignant pleural mesothelioma 11.8
2 benign mesothelioma 10.6
3 hypoglycemia 10.3
4 ocular motor apraxia 10.2
5 hypoglycemic coma 10.1
6 rare tumor 10.1
7 breast cancer 10.0
8 mesothelioma, malignant 10.0
9 fibroma 10.0
10 hemiplegia 10.0
11 47,xyy 10.0
12 benign fibrous mesothelioma 10.0
13 keloid disorder 10.0
14 glomangiomatosis 9.9 TP53 STAT6
15 granulosa cell tumor of the ovary 9.9 TP53 INS
16 low-grade astrocytoma 9.9 TP53 STAT6
17 adrenal cortex disease 9.9 TP53 INS
18 adrenal gland disease 9.8 TP53 INS
19 brain glioma 9.8 TP53 STAT6
20 hair disease 9.8 TP53 INS
21 gastrointestinal system benign neoplasm 9.8 TP53 INS
22 mediastinitis 9.8 TTR INS
23 marasmus 9.8 TTR INS
24 endocrine organ benign neoplasm 9.8 TP53 INS
25 kwashiorkor 9.8 TTR INS
26 nerve compression syndrome 9.7 TTR INS
27 decubitus ulcer 9.7 TTR INS
28 chronic ulcer of skin 9.7 TTR INS
29 autonomic nervous system disease 9.7 TTR INS
30 schistosomiasis 9.7 TP53 STAT6
31 cerebrovascular benign neoplasm 9.7 TTR TP53
32 carpal tunnel syndrome 9.7 TTR INS
33 colorectal adenoma 9.7 TP53 INS
34 heart conduction disease 9.7 TTR INS
35 papilloma of choroid plexus 9.7 TTR TP53
36 plasma cell neoplasm 9.6 TTR TP53
37 choroid plexus cancer 9.6 TTR TP53
38 gallbladder disease 9.6 TP53 INS
39 autonomic neuropathy 9.6 TTR INS
40 peripheral vascular disease 9.5 TP53 INS
41 liposarcoma 9.4 TP53 STAT6
42 contractures, pterygia, and variable skeletal fusions syndrome 1a 9.3 TTR TP53 INS
43 autosomal genetic disease 9.3 TTR TP53 INS
44 muscular disease 9.2 TTR TP53 INS
45 malaria 8.8 TTR TP53 STAT6 INS
46 diabetes mellitus, noninsulin-dependent 8.6 TTR TP53 RRAD NRF1 INS

Graphical network of the top 20 diseases related to Benign Pleural Mesothelioma:



Diseases related to Benign Pleural Mesothelioma
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Symptoms & Phenotypes for Benign Pleural Mesothelioma

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MGI Mouse Phenotypes related to Benign Pleural Mesothelioma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 renal/urinary system MP:0005367 8.92 INS STAT6 TP53 TTR
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Drugs & Therapeutics for Benign Pleural Mesothelioma

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Search Clinical Trials , NIH Clinical Center for Benign Pleural Mesothelioma

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Genetic Tests for Benign Pleural Mesothelioma

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Anatomical Context for Benign Pleural Mesothelioma

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MalaCards organs/tissues related to Benign Pleural Mesothelioma:

40
Lymph Node, Lung, Brain, Cortex, Heart, Adrenal Gland, Breast
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Publications for Benign Pleural Mesothelioma

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Articles related to Benign Pleural Mesothelioma:

(show top 50) (show all 52)
# Title Authors PMID Year
1
Cytological Profile of a Case of Malignant Mesothelioma of Pleura with Supraclavicular Lymph Node Metastasis. 61
29118480 2017
2
Health impact of the exposure to fibres with fluoro-edenitic composition on the residents in Biancavilla (Sicily, Italy): mortality and hospitalization from current data. 61
24968910 2014
3
[Cancer morbidity risks among workers of asbestos-cement productions]. 61
18467971 2008
4
Localized benign pleural mesothelioma: a case report. 61
14635508 2003
5
[Localized benign pleural mesothelioma observed at the Dakar University Hospital]. 61
11468593 2001
6
Granulocyte colony stimulating factor-producing diffuse malignant mesothelioma of pleura. 61
10440505 1999
7
[Pleural mesotheliomas. Current knowledge]. 61
10327696 1999
8
Video-assisted thoracoscopic excision of a benign cystic mesothelioma of pleura. 61
9785860 1998
9
HBME-1 and antithrombomodulin in the differential diagnosis of malignant mesothelioma of pleura. 61
9462271 1997
10
Localized benign pleural mesothelioma arising in a radiation field. 61
9156307 1997
11
TRANSTHORACIC FINE NEEDLE ASPIRATION CYTOLOGY IN DIAGNOSING NON-RESOLVING PNEUMONIAS - A STUDY OF 170 CASES. 61
28769433 1997
12
CD-34 and keratin expression distinguishes solitary fibrous tumor (fibrous mesothelioma) of pleura from desmoplastic mesothelioma. 61
7535740 1995
13
[Benign pleural mesothelioma. Report of 2 cases]. 61
8559004 1995
14
[Localized benign pleural mesothelioma]. 61
7990627 1994
15
[Localized pleural mesothelioma and benign pleural mesothelioma]. 61
8152134 1994
16
Mesothelioma of pleura and peritoneum following exposure to asbestos in the London area. 1965. 61
8398869 1993
17
Could development of malignant mesothelioma be induced by Yersinia enterocolitica infection? 61
8350778 1993
18
[Localized benign pleural mesothelioma]. 61
1896894 1991
19
Pleural fluid acidosis in the malignant variant of benign pleural mesothelioma. 61
2376201 1990
20
Localized fibrous mesothelioma of pleura following external ionizing radiation therapy. 61
2847898 1988
21
[Surgical treatment of localized mesothelioma of pleura--a reports of two cases]. 61
9301816 1988
22
[Recurrence of a benign pleural mesothelioma 18 years after its excision. Review of a series of 33 patients with a primary pleural tumor from 1958 to 1986]. 61
3446626 1987
23
[Histologic aspects of pleural mesothelioma]. 61
3327479 1987
24
[Clinical aspects and therapy of benign pleural mesothelioma. A case report]. 61
3581984 1987
25
[Recurrence of a benign pleural mesothelioma 18 years after excision. Review of a series of 33 patients with a primary tumor of the pleura from 1958 to 1986]. 61
3805179 1986
26
Diffuse malignant mesothelioma of pleura. Diagnosis and survival in 92 cases. 61
3742473 1986
27
Localised benign mesothelioma of pleura presenting as rapidly accumulating massive pleural effusion. 61
3596670 1986
28
Spontaneous detachment of benign mesothelioma into the pleural space and removal during pleuroscopy. 61
3699116 1986
29
Malignant mesothelioma cells in sputum. 61
3720479 1986
30
Diffuse malignant mesothelioma of pleura: diagnostic criteria based on an autopsy study. 61
6588749 1984
31
Localized fibrous mesothelioma of the pleura. 61
6694396 1984
32
Trends in mortality of diffuse malignant mesothelioma of pleura. 61
6134954 1983
33
[Benign pleural mesothelioma (author's transl)]. 61
7092107 1982
34
Benign pleural mesothelioma with tumour-induced hypoglycaemia. 61
7044359 1982
35
Pleural mesothelioma presenting as apparent recurrent pulmonary embolism. 61
7306468 1981
36
[Benign pleural mesothelioma]. 61
7445152 1980
37
Resection of giant benign fibrous mesothelioma of pleura. 61
6928541 1980
38
Mortality of chrysotile asbestos workers at the Balangero Mine, Northern Italy. 61
500777 1979
39
Localized fibrous "mesothelioma" of pleura (submesothelial fibroma): a clinicopathologic study of 18 cases. 61
421185 1979
40
Malignant mesothelioma of pleura: clinicopathologic observation. 61
270014 1977
41
Hypoglycemic coma associated with benign pleural mesothelioma. 61
1113546 1975
42
[Case of benign pleural mesothelioma]. 61
4819970 1974
43
Epidemiological and quantitative relationships between mesothelioma and asbestos on Tyneside. 61
4766195 1973
44
Mesothelioma of pleura-report of a case. 61
4794979 1973
45
[Hypoglycemic coma and benign pleural mesothelioma]. 61
5151183 1971
46
Mesothelioma of pleura with massive pleural effusion. 61
5648621 1968
47
Mesothelioma of pleura and peritoneum following exposure to asbestos in the London area. 61
5836565 1965
48
Mesothelioma of pleura. 61
13475849 1957
49
MESOTHELIOMA of pleura. 61
14866889 1951
50
MESOTHELIOMA of pleura. 61
14866890 1951
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Variations for Benign Pleural Mesothelioma

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Expression for Benign Pleural Mesothelioma

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Search GEO for disease gene expression data for Benign Pleural Mesothelioma.
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Pathways for Benign Pleural Mesothelioma

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Pathways related to Benign Pleural Mesothelioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Senescence and Autophagy in Cancer 1
11.18 TP53 INS
2
FOXA2 and FOXA3 transcription factor networks 1
10.6 TTR INS
3
Signaling events mediated by TCPTP 1
Show member pathways
 10.25 STAT6 INS
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GO Terms for Benign Pleural Mesothelioma

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Biological processes related to Benign Pleural Mesothelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 wound healing GO:0042060 8.96 TP53 INS
2 negative regulation of proteolysis GO:0045861 8.62 TP53 INS

Molecular functions related to Benign Pleural Mesothelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 9.43 TP53 STAT6 NRF1
2 protease binding GO:0002020 9.37 TP53 INS
3 DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 9.33 TP53 STAT6 NRF1
4 protein phosphatase binding GO:0019903 9.32 TP53 STAT6
5 identical protein binding GO:0042802 9.26 TTR TP53 STAT6 INS
6 core promoter sequence-specific DNA binding GO:0001046 8.62 TP53 NRF1
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Sources for Benign Pleural Mesothelioma

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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