MCID: BNZ003
MIFTS: 23

Benzylpenicillin Allergy

Categories: Immune diseases

Aliases & Classifications for Benzylpenicillin Allergy

MalaCards integrated aliases for Benzylpenicillin Allergy:

Name: Benzylpenicillin Allergy 12 15
Benzyl Benicillin Allergy 12
Penicillin G Allergy 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0040003
UMLS 71 C0571411

Summaries for Benzylpenicillin Allergy

Disease Ontology : 12 A beta-lactam allergy that has allergic trigger benzylpenicillin.

MalaCards based summary : Benzylpenicillin Allergy, also known as benzyl benicillin allergy, is related to penicillin allergy and pancreatic vasoactive intestinal peptide producing tumor. An important gene associated with Benzylpenicillin Allergy is TNFRSF1B (TNF Receptor Superfamily Member 1B), and among its related pathways/superpathways are Rheumatoid arthritis and Cellular Transformation by HTLV1. Affiliated tissues include bone, skin and cervix, and related phenotype is digestive/alimentary.

Related Diseases for Benzylpenicillin Allergy

Diseases related to Benzylpenicillin Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 150)
# Related Disease Score Top Affiliating Genes
1 penicillin allergy 30.0 IFNG ATP12A
2 pancreatic vasoactive intestinal peptide producing tumor 10.0 ATP4A ATP12A
3 hemangioma of intra-abdominal structure 10.0 ATP4A ATP12A
4 displacement of cardia through esophageal hiatus 10.0 ATP4A ATP12A
5 gastric hemangioma 10.0 ATP4A ATP12A
6 acquired gastric outlet stenosis 10.0 ATP4A ATP12A
7 angiodysplasia of intestine 10.0 ATP4A ATP12A
8 angiodysplasia 10.0 ATP4A ATP12A
9 median arcuate ligament syndrome 10.0 ATP4A ATP12A
10 granulomatous gastritis 10.0 ATP4A ATP12A
11 bacterial esophagitis 10.0 ATP4A ATP12A
12 lingual goiter 10.0 ATP4A ATP12A
13 cascade stomach 10.0 ATP4A ATP12A
14 gastrojejunal ulcer 10.0 ATP4A ATP12A
15 fungal esophagitis 10.0 ATP4A ATP12A
16 gastric gastrinoma 10.0 ATP4A ATP12A
17 fungal gastritis 10.0 ATP4A ATP12A
18 superior mesenteric artery syndrome 10.0 ATP4A ATP12A
19 cervix erosion 10.0 ATP4A ATP12A
20 pneumatosis cystoides intestinalis 10.0 ATP4A ATP12A
21 dieulafoy lesion 10.0 ATP4A ATP12A
22 esophagus sarcoma 10.0 ATP4A ATP12A
23 esophagus melanoma 10.0 ATP4A ATP12A
24 polyposis, skin pigmentation, alopecia, and fingernail changes 10.0 ATP4A ATP12A
25 necrotizing gastritis 10.0 ATP4A ATP12A
26 central nervous system origin vertigo 10.0 ATP4A ATP12A
27 chronic laryngitis 10.0 ATP4A ATP12A
28 laryngitis 10.0 ATP4A ATP12A
29 cefuroxime allergy 10.0 ATP4A ATP12A
30 gastroduodenitis 10.0 ATP4A ATP12A
31 duodenitis 10.0 ATP4A ATP12A
32 chronic intestinal vascular insufficiency 10.0 ATP4A ATP12A
33 peptic ulcer perforation 10.0 ATP4A ATP12A
34 rumination disorder 10.0 ATP4A ATP12A
35 blind loop syndrome 10.0 ATP4A ATP12A
36 crab allergy 10.0 ATP4A ATP12A
37 acute laryngitis 10.0 ATP4A ATP12A
38 duodenal gastrinoma 10.0 ATP4A ATP12A
39 gastric dilatation 10.0 ATP4A ATP12A
40 diclofenac allergy 10.0 ATP4A ATP12A
41 internal hemorrhoid 10.0 ATP4A ATP12A
42 hemorrhoid 10.0 ATP4A ATP12A
43 lymphocytic gastritis 10.0 ATP4A ATP12A
44 duodenal obstruction 10.0 ATP4A ATP12A
45 pancreatic gastrinoma 10.0 ATP4A ATP12A
46 functional diarrhea 10.0 ATP4A ATP12A
47 gastritis, familial giant hypertrophic 10.0 ATP4A ATP12A
48 eosinophilic gastritis 10.0 ATP4A ATP12A
49 gastric antral vascular ectasia 10.0 ATP4A ATP12A
50 severe cutaneous adverse reaction 10.0 TNFRSF1B ATP12A

Graphical network of the top 20 diseases related to Benzylpenicillin Allergy:



Diseases related to Benzylpenicillin Allergy

Symptoms & Phenotypes for Benzylpenicillin Allergy

MGI Mouse Phenotypes related to Benzylpenicillin Allergy:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 8.92 ATP12A ATP4A IFNG TNFRSF1B

Drugs & Therapeutics for Benzylpenicillin Allergy

Search Clinical Trials , NIH Clinical Center for Benzylpenicillin Allergy

Genetic Tests for Benzylpenicillin Allergy

Anatomical Context for Benzylpenicillin Allergy

MalaCards organs/tissues related to Benzylpenicillin Allergy:

40
Bone, Skin, Cervix, B Cells

Publications for Benzylpenicillin Allergy

Articles related to Benzylpenicillin Allergy:

# Title Authors PMID Year
1
[Medicine hypersensitivity--case report]. 61
15517938 2004
2
[Role of bacterial infection in the pathophysiology of benzylpenicillin allergy]. 61
12712830 2003

Variations for Benzylpenicillin Allergy

Expression for Benzylpenicillin Allergy

Search GEO for disease gene expression data for Benzylpenicillin Allergy.

Pathways for Benzylpenicillin Allergy

Pathways related to Benzylpenicillin Allergy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.23 PTH IFNG
2
Show member pathways
10.85 TNFRSF1B IFNG
3 10.61 PTH IFNG
4 10.14 TNFRSF1B IFNG

GO Terms for Benzylpenicillin Allergy

Biological processes related to Benzylpenicillin Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extrinsic apoptotic signaling pathway GO:0097191 9.4 TNFRSF1B IFNG
2 potassium ion import across plasma membrane GO:1990573 9.37 ATP4A ATP12A
3 cellular sodium ion homeostasis GO:0006883 9.32 ATP4A ATP12A
4 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.26 TNFRSF1B IFNG
5 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.16 ATP4A ATP12A
6 sodium ion export across plasma membrane GO:0036376 8.96 ATP4A ATP12A
7 cellular potassium ion homeostasis GO:0030007 8.62 ATP4A ATP12A

Molecular functions related to Benzylpenicillin Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 9.16 ATP4A ATP12A
2 potassium-transporting ATPase activity GO:0008556 8.96 ATP4A ATP12A
3 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A

Sources for Benzylpenicillin Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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