MCID: BRB001
MIFTS: 41

Beriberi

Categories: Cardiovascular diseases, Metabolic diseases, Neuronal diseases, Rare diseases, Respiratory diseases

Aliases & Classifications for Beriberi

MalaCards integrated aliases for Beriberi:

Name: Beriberi 12 75 53 37 55 44 15 17 72 33
Thiamine Deficiency 53 55 17 72 33
Vitamin B1 Deficiency 53

Classifications:



External Ids:

Disease Ontology 12 DOID:13725
KEGG 37 H01566
ICD9CM 35 265.0
MeSH 44 D001602
NCIt 50 C34418
SNOMED-CT 68 36656008
ICD10 33 E51 E51.1
UMLS 72 C0005122 C0039841

Summaries for Beriberi

NIH Rare Diseases : 53 Beriberi is a condition that occurs in people who are deficient in thiamine (vitamin B1). There are two major types of beriberi: wet beriberi which affects the cardiovascular system and dry beriberi which affects the nervous system. People with wet beriberi may experience increased heart rate, shortness of breath, and swelling of the lower legs. Signs and symptoms of dry beriberi include difficulty walking; loss of feeling in the hands and/or feet; paralysis of the lower legs; mental confusion; speech difficulty; pain; and/or vomiting. Beriberi is rare in the United States since many foods are now vitamin enriched; however, alcohol abuse, dialysis and taking high doses of diuretics increases the risk of developing the condition. In most cases, beriberi occurs sporadically in people with no family history of the condition. A rare condition known as genetic beriberi is inherited (passed down through families) and is associated with an inability to absorb thiamine from foods. Treatment generally includes thiamine supplementation, given by injection or taken by mouth.

MalaCards based summary : Beriberi, also known as thiamine deficiency, is related to wernicke-korsakoff syndrome and megaloblastic anemia. An important gene associated with Beriberi is TKT (Transketolase). The drugs Metformin and leucovorin have been mentioned in the context of this disorder. Affiliated tissues include heart, brain and liver, and related phenotypes are Decreased viability and Decreased viability

Disease Ontology : 12 A thiamine deficiency disease that is characterized by being severe and chronic.

KEGG : 37
Beriberi is the classical syndrome caused by thiamine (vitamin B1) deficiency. Beriberi has two major clinical manifestations, dry beriberi characterized by neurologic manifestations that include peripheral neuropathy and acute encephalopathy, and wet beriberi with cardiovascular involvement including high cardiac output heart failure. Rarely, a fulminant or pernicious variant, termed Shoshin beriberi may occur, and is characterized by cardiovascular collapse. Appropriate management of this form is mandatory since thiamine supplementation leads to rapid recovery while untreated forms are fatal.

Wikipedia : 75 Thiamine deficiency is a medical condition of low levels of thiamine (vitamin B1). A severe and chronic... more...

Related Diseases for Beriberi

Diseases in the Beriberi family:

Dry Beriberi

Diseases related to Beriberi via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 294, show less)
# Related Disease Score Top Affiliating Genes
1 wernicke-korsakoff syndrome 30.1 TKT SLC19A2
2 megaloblastic anemia 28.7 TPK1 SLC19A2
3 wet beriberi 12.7
4 dry beriberi 12.7
5 thiamine deficiency disease 12.5
6 cerebral beriberi 12.3
7 wernicke encephalopathy 11.6
8 korsakoff's amnesic syndrome 11.4
9 heart disease 10.7
10 lactic acidosis 10.6
11 encephalopathy 10.6
12 polyneuropathy 10.5
13 neuropathy 10.5
14 metabolic acidosis 10.5
15 alcohol dependence 10.4
16 congestive heart failure 10.4
17 peripheral nervous system disease 10.4
18 cardiogenic shock 10.3
19 pathologic nystagmus 10.3
20 hydrops, lactic acidosis, and sideroblastic anemia 10.3
21 pulmonary edema 10.3
22 guillain-barre syndrome 10.3
23 paresthesia 10.3
24 neuroblastoma 1 10.2
25 cerebellar degeneration 10.2
26 atrial standstill 1 10.2
27 ataxia and polyneuropathy, adult-onset 10.2
28 kearns-sayre syndrome 10.2
29 leptin deficiency or dysfunction 10.2
30 pulmonary hypertension 10.2
31 alcohol use disorder 10.2
32 subacute delirium 10.1
33 graves disease 1 10.1
34 cardiac arrest 10.1
35 short bowel syndrome 10.1
36 respiratory failure 10.1
37 acute kidney failure 10.1
38 myopathy 10.1
39 pellagra 10.1
40 huntington disease 10.0
41 body mass index quantitative trait locus 1 10.0
42 human immunodeficiency virus type 1 10.0
43 malaria 10.0
44 ptosis 10.0
45 lymphocytic leukemia 10.0
46 hepatic coma 10.0
47 diarrhea 10.0
48 hepatic encephalopathy 10.0
49 allergic encephalomyelitis 10.0
50 ocular motor apraxia 10.0
51 body mass index quantitative trait locus 11 10.0
52 body mass index quantitative trait locus 9 10.0
53 body mass index quantitative trait locus 8 10.0
54 body mass index quantitative trait locus 4 10.0
55 body mass index quantitative trait locus 10 10.0
56 body mass index quantitative trait locus 7 10.0
57 body mass index quantitative trait locus 12 10.0
58 body mass index quantitative trait locus 14 10.0
59 body mass index quantitative trait locus 18 10.0
60 body mass index quantitative trait locus 19 10.0
61 body mass index quantitative trait locus 20 10.0
62 amnestic disorder 10.0
63 adult respiratory distress syndrome 10.0
64 hemopericardium 10.0
65 pericardial effusion 10.0
66 toxic shock syndrome 10.0
67 renal tubular acidosis 10.0
68 neuritis 10.0
69 anuria 10.0
70 hyperglycemia 10.0
71 kidney disease 10.0
72 myocarditis 10.0
73 dysphagia 10.0
74 amyotrophic lateral sclerosis 1 9.9
75 papillomatosis, confluent and reticulated 9.9
76 leigh syndrome 9.9
77 proteasome-associated autoinflammatory syndrome 1 9.9
78 yemenite deaf-blind hypopigmentation syndrome 9.9
79 anorexia nervosa 9.9
80 leukemia, acute lymphoblastic 9.9
81 carbonic anhydrase va deficiency, hyperammonemia due to 9.9
82 chorea, childhood-onset, with psychomotor retardation 9.9
83 fetal alcohol syndrome 9.9
84 alcohol-related birth defect 9.9
85 hepatorenal syndrome 9.9
86 choreatic disease 9.9
87 dementia 9.9
88 alcoholic neuropathy 9.9
89 epilepsy 9.9
90 lateral sclerosis 9.9
91 liver disease 9.9
92 brain edema 9.9
93 mitochondrial myopathy 9.9
94 diabetes mellitus 9.9
95 exophthalmos 9.9
96 systolic heart failure 9.9
97 hypoglycemia 9.9
98 auditory neuropathy spectrum disorder 9.9
99 glioma 9.9
100 spastic paraparesis 9.9
101 hypoxia 9.9
102 posttransplant acute limbic encephalitis 9.9
103 glial tumor 9.9
104 overgrowth syndrome 9.9
105 craniofacial-deafness-hand syndrome 9.9
106 impotence 9.9
107 thrombophlebitis 9.9
108 scarlet fever 9.9
109 oral cavity cancer 9.9
110 febrile seizures 9.9
111 hypercholesterolemia, familial, 1 9.9
112 schizophrenia 9.9
113 strabismus 9.9
114 celiac disease 1 9.9
115 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 9.9
116 hypoascorbemia 9.9
117 immune deficiency disease 9.9
118 thiamine-responsive megaloblastic anemia syndrome 9.9
119 nasopharyngeal carcinoma 9.9
120 myocardial infarction 9.9
121 microvascular complications of diabetes 3 9.9
122 microvascular complications of diabetes 4 9.9
123 microvascular complications of diabetes 6 9.9
124 microvascular complications of diabetes 7 9.9
125 cyanosis, transient neonatal 9.9
126 striatal degeneration, autosomal dominant 2 9.9
127 angina pectoris 9.9
128 deficiency anemia 9.9
129 acute diarrhea 9.9
130 vitamin b12 deficiency 9.9
131 withdrawal disorder 9.9
132 aphasia 9.9
133 primary hyperparathyroidism 9.9
134 nephrotic syndrome 9.9
135 alcoholic hepatitis 9.9
136 pancytopenia 9.9
137 acute kidney tubular necrosis 9.9
138 dilated cardiomyopathy 9.9
139 alcoholic cardiomyopathy 9.9
140 gout 9.9
141 hyperparathyroidism 9.9
142 familial hypercholesterolemia 9.9
143 poems syndrome 9.9
144 critical illness polyneuropathy 9.9
145 hypothyroidism 9.9
146 cholera 9.9
147 rheumatic disease 9.9
148 pericarditis 9.9
149 optic nerve disease 9.9
150 enthesopathy 9.9
151 drug-induced hepatitis 9.9
152 gastroenteritis 9.9
153 macrocytic anemia 9.9
154 sensory peripheral neuropathy 9.9
155 ischemia 9.9
156 purpura 9.9
157 plague 9.9
158 acute myocarditis 9.9
159 gastritis 9.9
160 coronary stenosis 9.9
161 polyradiculoneuropathy 9.9
162 uremia 9.9
163 liver cirrhosis 9.9
164 apical myocardial infarction 9.9
165 paraplegia 9.9
166 spinal stenosis 9.9
167 axonal neuropathy 9.9
168 muscular atrophy 9.9
169 gastrointestinal system disease 9.9
170 end stage renal failure 9.9
171 hyperthyroidism 9.9
172 intestinal obstruction 9.9
173 ileus 9.9
174 paralytic ileus 9.9
175 oropharynx cancer 9.9
176 vasculitis 9.9
177 eating disorder 9.9
178 crohn's disease 9.9
179 mechanical strabismus 9.9
180 pulmonary embolism 9.9
181 47,xyy 9.9
182 hypertrophic cardiomyopathy 9.9
183 heavy metal poisoning 9.9
184 dysautonomia 9.9
185 syncope 9.9
186 acute liver failure 9.9
187 rare surgical neurologic disease 9.9
188 anisocoria 9.8
189 atherosclerosis susceptibility 9.8
190 intussusception 9.8
191 leukemia, acute monocytic 9.8
192 medulloblastoma 9.8
193 ovarian cancer 9.8
194 parkinson disease, late-onset 9.8
195 pheochromocytoma 9.8
196 tetralogy of fallot 9.8
197 torticollis 9.8
198 down syndrome 9.8
199 ascites, chylous 9.8
200 cerebrocortical degeneration of infancy 9.8
201 duodenal atresia 9.8
202 3-methylglutaconic aciduria, type iii 9.8
203 osteogenic sarcoma 9.8
204 sudden infant death syndrome 9.8
205 pelizaeus-merzbacher disease 9.8
206 supranuclear palsy, progressive, 1 9.8
207 leukemia, acute myeloid 9.8
208 branchiootic syndrome 1 9.8
209 dermatitis, atopic 9.8
210 ventricular fibrillation, paroxysmal familial, 1 9.8
211 propionic acidemia 9.8
212 thiamine metabolism dysfunction syndrome 2 9.8
213 major depressive disorder 9.8
214 hepatitis c virus 9.8
215 diabetes mellitus, ketosis-prone 9.8
216 acute promyelocytic leukemia 9.8
217 gastric cancer 9.8
218 riboflavin deficiency 9.8
219 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 9.8
220 speech and communication disorders 9.8
221 foodborne botulism 9.8
222 infant botulism 9.8
223 fetal alcohol spectrum disorder 9.8
224 diffuse large b-cell lymphoma 9.8
225 biotin deficiency 9.8
226 atrioventricular block 9.8
227 adrenal gland pheochromocytoma 9.8
228 autism spectrum disorder 9.8
229 lymphoma 9.8
230 colitis 9.8
231 glucose intolerance 9.8
232 blind loop syndrome 9.8
233 western equine encephalitis 9.8
234 hydrocephalus 9.8
235 pertussis 9.8
236 vitamin k deficiency bleeding 9.8
237 diabetic autonomic neuropathy 9.8
238 visual epilepsy 9.8
239 detrusor sphincter dyssynergia 9.8
240 bronchopneumonia 9.8
241 dysentery 9.8
242 telangiectasis 9.8
243 relapsing fever 9.8
244 plasmodium falciparum malaria 9.8
245 mental depression 9.8
246 ventricular septal defect 9.8
247 heart septal defect 9.8
248 duodenal ulcer 9.8
249 vascular disease 9.8
250 status epilepticus 9.8
251 hepatitis c 9.8
252 rectum cancer 9.8
253 constipation 9.8
254 kernicterus 9.8
255 glycogen storage disease 9.8
256 food allergy 9.8
257 lipid metabolism disorder 9.8
258 vaccinia 9.8
259 pleural empyema 9.8
260 retrograde amnesia 9.8
261 endophthalmitis 9.8
262 nutritional deficiency disease 9.8
263 sleep disorder 9.8
264 dystonia 9.8
265 bronchitis 9.8
266 inherited metabolic disorder 9.8
267 b-cell lymphoma 9.8
268 peritonitis 9.8
269 monocytic leukemia 9.8
270 hypopharynx cancer 9.8
271 ulcerative colitis 9.8
272 nervous system disease 9.8
273 myeloid leukemia 9.8
274 pyomyositis 9.8
275 viral infectious disease 9.8
276 stomatitis 9.8
277 aphthous stomatitis 9.8
278 diabetic neuropathy 9.8
279 microcephaly 9.8
280 48,xyyy 9.8
281 acute monoblastic leukemia 9.8
282 congenital hydrocephalus 9.8
283 marchiafava bignami disease 9.8
284 sutton disease 2 9.8
285 wallerian degeneration 9.8
286 depression 9.8
287 brain injury 9.8
288 chronic pain 9.8
289 head injury 9.8
290 hypotonia 9.8
291 myoclonus 9.8
292 seizure disorder 9.8
293 traumatic brain injury 9.8
294 tremor 9.8

Graphical network of the top 20 diseases related to Beriberi:



Diseases related to Beriberi

Symptoms & Phenotypes for Beriberi

GenomeRNAi Phenotypes related to Beriberi according to GeneCards Suite gene sharing:

26 (showing 12, show less)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00055-A-2 9.5 EPHA3
2 Decreased viability GR00107-A-1 9.5 TPK1
3 Decreased viability GR00173-A 9.5 TPK1
4 Decreased viability GR00221-A-3 9.5 TPK1
5 Decreased viability GR00221-A-4 9.5 EPHA3 TPK1
6 Decreased viability GR00240-S-1 9.5 TPK1
7 Decreased viability GR00301-A 9.5 EPHA3
8 Decreased viability GR00342-S-1 9.5 EPHA3 TPK1
9 Decreased viability GR00342-S-2 9.5 TPK1
10 Decreased viability GR00342-S-3 9.5 TPK1
11 Decreased viability GR00381-A-1 9.5 TPK1
12 Decreased viability GR00402-S-2 9.5 EPHA3 TPK1

Drugs & Therapeutics for Beriberi

Drugs for Beriberi (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 76, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Metformin Approved Phase 4 657-24-9 4091 14219
2
leucovorin Approved Phase 4 58-05-9 143 6006
3
Trimethoprim Approved, Vet_approved Phase 4 738-70-5 5578
4
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 5754
5
Hydrocortisone acetate Approved, Vet_approved Phase 4 50-03-3
6
Lamivudine Approved, Investigational Phase 4 134678-17-4 60825
7
Entecavir Approved, Investigational Phase 4 142217-69-4 153941
8
Folic acid Approved, Nutraceutical, Vet_approved Phase 4 59-30-3 6037
9
Thiamine Approved, Investigational, Nutraceutical, Vet_approved Phase 4 59-43-8, 70-16-6 1130
10
Vitamin C Approved, Nutraceutical Phase 4 50-81-7 54670067 5785
11 Folic Acid Antagonists Phase 4
12 Cytochrome P-450 Enzyme Inhibitors Phase 4
13 Renal Agents Phase 4
14 Antiparasitic Agents Phase 4
15 Anti-Infective Agents, Urinary Phase 4
16 Antiprotozoal Agents Phase 4
17 Antimalarials Phase 4
18 Hypoglycemic Agents Phase 4
19 Micronutrients Phase 4
20 Trace Elements Phase 4
21 Vitamins Phase 4
22 Folate Phase 4
23 Vitamin B9 Phase 4
24 Vitamin B Complex Phase 4
25 Nutrients Phase 4
26 Thiamin Phase 4
27 Protective Agents Phase 4
28 Anti-Inflammatory Agents Phase 4
29 Hydrocortisone-17-butyrate Phase 4
30 Hydrocortisone 17-butyrate 21-propionate Phase 4
31 Hydrocortisone hemisuccinate Phase 4
32 Pharmaceutical Solutions Phase 4
33 Antioxidants Phase 4
34 Anti-Infective Agents Phase 4
35 Reverse Transcriptase Inhibitors Phase 4
36 Nucleic Acid Synthesis Inhibitors Phase 4
37 Anti-HIV Agents Phase 4
38 Anti-Retroviral Agents Phase 4
39 Antiviral Agents Phase 4
40
Ethanol Approved Phase 2, Phase 3 64-17-5 702
41
Magnesium Sulfate Approved, Investigational, Vet_approved Phase 2, Phase 3 7487-88-9 24083
42 Analgesics Phase 2, Phase 3
43 Tocolytic Agents Phase 2, Phase 3
44 Central Nervous System Depressants Phase 2, Phase 3
45 Anti-Arrhythmia Agents Phase 2, Phase 3
46 Anticonvulsants Phase 2, Phase 3
47 calcium channel blockers Phase 2, Phase 3
48 pyruvate Phase 2
49 Vasoconstrictor Agents Phase 2
50 Hormones Phase 2
51 glucocorticoids Phase 2
52 Hormone Antagonists Phase 2
53 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2
54
Iron Approved, Experimental Phase 1 15438-31-0, 7439-89-6 23925 27284
55
Thiamine Pyrophosphate Phase 1 154-87-0 1132
56
Hydroxocobalamin Approved 13422-51-0 11953898 15589840
57
Dopamine Approved 51-61-6, 62-31-7 681
58
Metoclopramide Approved, Investigational 364-62-5 4168
59
Cyanocobalamin Approved, Nutraceutical 68-19-9 44176380
60
Calcium Approved, Nutraceutical 7440-70-2 271
61
Cobalamin Experimental 13408-78-1 6857388
62 diuretics
63 Hematinics
64 Vitamin B 12
65 Vitamin B12
66 Peripheral Nervous System Agents
67 Neurotransmitter Agents
68 Gastrointestinal Agents
69 Antiemetics
70 Dopamine Agents
71 Dopamine Antagonists
72 Autonomic Agents
73 Dopamine D2 Receptor Antagonists
74 Anesthetics
75 Calcium, Dietary
76 Immunosuppressive Agents

Interventional clinical trials:

(showing 41, show less)
# Name Status NCT ID Phase Drugs
1 Preoperative Parenteral Thiamine Supplementation in Patients Undergoing Heart Surgery - a Pilot Study Unknown status NCT01524315 Phase 4 Vitamin B1-ratiopharm;Placebo
2 Prevention of Renal Complications of Diabetes With Thiamine Unknown status NCT01725412 Phase 4
3 Thiamin Deficiency in Obese Thai Children Completed NCT02464865 Phase 4 Thiamine 1;Thiamine 2
4 Thiamine Supplementation in High Risk Cardiac Surgery Patients Completed NCT03306732 Phase 4 Thiamine hydrochloride (200mg) dissolved in 100 ml of normal saline;Normal saline (100ml)
5 Optimum Thiamine Intervention (OpT In) for Treatment and Prevention of Wernicke-Korsakoff Syndrome (WKS): A Randomised Controlled Trial Completed NCT02788552 Phase 4 Thiamine Hydrochloride
6 The Effect of SLC19A3 Inhibition on the Pharmacokinetics of Thiamine Recruiting NCT03746106 Phase 4 Trimethoprim;Metformin
7 Effects of Vitamin C, Thiamine and Hydrocortisone in Septic Shock: a Randomized, Controlled Trial Not yet recruiting NCT04039815 Phase 4 Ascorbic acid-Vitamin B1-Hydrocortisone;Placebo
8 The Incidence of Lactic Acidosis During Entecavir Treatment in Chronic Hepatitis B Patients With Severe Cirrhosis or Hepatic Failure Terminated NCT01354652 Phase 4 entecavir, lamivudine
9 A Prospective Randomised Controlled Trial of the Effect of Magnesium Sulphate Administration on Red Cell Transketolase Activity in Alcohol Dependent Patients at Risk of Wernicke Korsakoff Syndrome Treated With Thiamine Completed NCT03466528 Phase 2, Phase 3 Magnesium Sulfate;Pabrinex
10 Ascorbic Ccid, Hydrocortisone, and Thiamine in Sepsis and Septic Shock - A Randomized, Double-Blind, Placebo-Controlled Trial Recruiting NCT03389555 Phase 2, Phase 3 vitamin C, vitamin B1, hydrocortisone;Normal saline
11 Evaluation of Hydrocortisone, Vitamin C and Thiamine for the Treatment of Septic Shock Recruiting NCT03380507 Phase 2, Phase 3 Triple therapy group
12 Effect of IV Vitamin C, Thiamine, and Steroids on Mortality of Septic Shock Not yet recruiting NCT03828929 Phase 3 Vitamin C;Normal saline
13 The Effect of Thiamine vs. Placebo on VO2 in Critical Illness Completed NCT01985685 Phase 2 Thiamine
14 Thiamine as a Renal Protective Agent in Septic Shock: A Randomized, Controlled Study Recruiting NCT03550794 Phase 2 Thiamine Hydrochloride;Placebo
15 Randomized, Double-blind, Placebo-controlled Trial of the Effect of Thiamine on Oxygen Consumption After In-hospital Cardiac Arrest. Recruiting NCT02974257 Phase 2 Thiamine
16 Thiamine as Adjunctive Therapy for Diabetic Ketoacidosis Recruiting NCT03717896 Phase 2 200mg IV thiamine in 50mL 0.9% saline;Placebo
17 A Randomized, Double Blind, Placebo-Controlled Trial to Investigate the Effect of Vitamin C, Hydrocortisone and Thiamine on the Outcome of Patients With Septic Shock Recruiting NCT03592693 Phase 2 Combined Vitamin C and Stress-Dose Hydrocortisone;Placebo plus placebo
18 Effect of Combined Vitamin C, Stress-dose Steroids, and Thiamine on Cerebral Autoregulation and Functional Outcomes of Patients With Septic Shock Recruiting NCT03649633 Phase 1, Phase 2 Stress-dose Hydrocortisone plus Vitamin C;isotonic sodium chloride solution placebo plus isotonic sodium chloride solution placebo
19 Outcomes of Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in the Early Treatment of Sepsis. Active, not recruiting NCT03422159 Phase 2 Ascorbic Acid;Thiamine;Hydrocortisone;Sodium Chloride 0.9%
20 Randomized Placebo Controlled Trial of High Dose Intravenous Thiamine for the Prevention of Delirium in Allogeneic Hematopoietic Stem Cell Transplantation Enrolling by invitation NCT03263442 Phase 2 Thiamine;Normal saline
21 Pharmacokinetics of Thiamine in Breastfeeding Mothers and Infants Completed NCT01864057 Phase 1 thiamine hydrochloride 100 mg
22 Thiamin Fortified Fish Sauce as a Means of Combating Infantile Beriberi in Rural Cambodia Completed NCT02221063 Phase 1
23 Thiamine Supplementation in Heart Failure: a Pilot Randomized Controlled Crossover Trial Recruiting NCT03228030 Phase 1
24 Thiamine Supplementation in Patients With Septic Shock: A Randomized, Double Blind, Placebo Controlled Trial Withdrawn NCT03122678 Phase 1 Thiamine;Placebos
25 Determination Study of Dry Beriberi in Patients Native to the Comoro Archipelago, in Mayotte (MABECO). Unknown status NCT00934349
26 Evaluating the B1 Status in Eating Disorder Female Adolescent Patients Unknown status NCT02164487
27 Assessment of Nutritional Consequences of Sleeve Gastrectomy Unknown status NCT01475903
28 Cutaneous Denervation in Alcoholic Neuropathy Unknown status NCT00190073
29 Efficacy of Thiamine Supplement for Improve Cardiovascular Function in Patients With Severe Hyperthyroidism Completed NCT02767245 Thiamine
30 Thiamine Supplementation to Improve Cardiac Function in Patients With Congestive Heart Failure on Long-term Treatment With Diuretic Drugs Completed NCT00770107 Thiamine;Placebo
31 The Effect of Thiamine on VO2 Levels in Critically Ill Patients Completed NCT01462279 Thiamine
32 The Prevalence of Thiamin Deficiency in Ambulatory Patients With Heart Failure Completed NCT00953823
33 Epidemiology of Long QTand Asian Sudden Death in Sleep Completed NCT00005367
34 Pilot Study for the Evaluation of the Effectiveness of Natural Versus Synthetic Vitamin B Complexes in Humans. Completed NCT03444155
35 Glycemic Index of Bread: Fiber or Minerals? This is the Question. Completed NCT02598986
36 A Study to Establish a Case Definition of Thiamine Responsive Disorders (TRD) Among Infants in Lao PDR Recruiting NCT03626337 Thiamine 100 MG/ML
37 The Relation Between Acute Changes in the Systemic Inflammatory Response, Thiamine and Magnesium Concentrations and Transketolase Activity After Elective Knee Arthroplasty. Recruiting NCT03554668
38 Thiamine As An Adjuvant Therapy For Hyperlactatemia In Septic Shock Patients: A Prospective Randomized Study Recruiting NCT03649009 Thiamine;Hydrocortisone
39 Improving Estimates of the Global Burden of Thiamine Deficiency Disorders and Approaches to Their Control: Trial of Thiamine Supplementation in Cambodia Active, not recruiting NCT03616288
40 Evaluation of s100β, NSE and Glial Fibrillary Acidic Protein Levels in Preoperative and Postoperative Renal Transplantation Not yet recruiting NCT04042272
41 A Randomized Double Blinded Pilot Study of Oral Thiamine in the Symptomatic Treatment of Painful Diabetic Peripheral Neuropathy Withdrawn NCT00279266 Thiamine

Search NIH Clinical Center for Beriberi

Inferred drug relations via UMLS 72 / NDF-RT 51 :


Thiamine hydrochloride
Thiamine Mononitrate

Cochrane evidence based reviews: beriberi

Genetic Tests for Beriberi

Anatomical Context for Beriberi

MalaCards organs/tissues related to Beriberi:

41
Heart, Brain, Liver, Thalamus, Cortex, Testes, Kidney

Publications for Beriberi

Articles related to Beriberi:

(showing 2275, show less)
# Title Authors PMID Year
1
Thiamine deficiency-related brain dysfunction in chronic liver failure. 9 38
19067139 2009
2
Outbreak of life-threatening thiamine deficiency in infants in Israel caused by a defective soy-based formula. 9 38
15687431 2005
3
Neuronal localization of the 25-kDa specific thiamine triphosphatase in rodent brain. 9 38
15120844 2004
4
Thiamine deficiency and malaria in adults from southeast Asia. 9 38
10028983 1999
5
Clinical relevance of thiamine status amongst hospitalized elderly patients. 9 38
9933732 1999
6
Thiamine deficiency decreases steady-state transketolase and pyruvate dehydrogenase but not alpha-ketoglutarate dehydrogenase mRNA levels in three human cell types. 9 38
9521628 1998
7
Thiamine pyrophosphate effect and normalized erythrocyte transketolase activity ratio in Wernicke-Korsakoff patients and acute alcoholics undergoing detoxification. 9 38
8949966 1996
8
Thiamine pyrophosphate-requiring enzymes are altered during pyrithiamine-induced thiamine deficiency in cultured human lymphoblasts. 9 38
8683340 1996
9
Brain thiamine, its phosphate esters, and its metabolizing enzymes in Alzheimer's disease. 9 38
8619543 1996
10
Molecular cloning of tissue-specific transcripts of a transketolase-related gene: implications for the evolution of new vertebrate genes. 9 38
8838793 1996
11
Reduced activities of thiamine-dependent enzymes in brains of alcoholics in the absence of Wernicke's encephalopathy. 9 38
7485819 1995
12
Thiamine deficiency in cultured neuroblastoma cells: effect on mitochondrial function and peripheral benzodiazepine receptors. 9 38
7722487 1995
13
Heterogeneous expression of transketolase in rat brain. 9 38
7861132 1995
14
The thiamine-dependent hysteretic behavior of human transketolase: implications for thiamine deficiency. 9 38
7861245 1995
15
Thiamine utilization in the pathogenesis of alcohol-induced brain damage. 9 38
8974347 1994
16
Cloning of human transketolase cDNAs and comparison of the nucleotide sequence of the coding region in Wernicke-Korsakoff and non-Wernicke-Korsakoff individuals. 9 38
8419340 1993
17
Genetic heterogeneity of mitochondrial genome in thiamine deficient Leigh syndrome patients. 38
31352295 2019
18
Role of Thiamin in Health and Disease. 38
30644592 2019
19
First report of an outbreak of cerebral coenurosis in Dhofari goats in Oman. 38
31390436 2019
20
Thiamine deficiency as a possible cofactor causing cognitive dysfunction in a patient with end-stage gastric cancer
. 38
31232276 2019
21
Excessive soft drink may induce pulmonary hypertension via thiamine deficiency. 38
31373121 2019
22
Citreoviridin induces myocardial apoptosis through PPAR-γ-mTORC2-mediated autophagic pathway and the protective effect of thiamine and selenium. 38
31419397 2019
23
Acute Shoshin beriberi syndrome immediately post-kidney transplant with rapid recovery after thiamine administration. 38
31124207 2019
24
Development and validation of a dried blood spot test for thiamine deficiency among infants by HPLC-fluorimetry. 38
31353499 2019
25
Thiamine deficiency affects glucose transport and β-oxidation in rats. 38
31259440 2019
26
Matched Retrospective Cohort Study of Thiamine to Treat Persistent Hyperlactatemia in Pediatric Septic Shock. 38
31274776 2019
27
Thiamine Use in Sepsis: B1 for Everyone? 38
31135480 2019
28
Subtle object location perception deficits in Korsakoff's syndrome. 38
31304867 2019
29
Recurrent Wernicke's encephalopathy in pregnancy: A case report. 38
29272216 2019
30
Arsenic Neurotoxicity in Humans. 38
31336801 2019
31
Genetic defects of thiamine transport and metabolism: A review of clinical phenotypes, genetics, and functional studies. 38
31095747 2019
32
Atypical presentation of a forgotten disease: refractory hypotension in beriberi. 38
31285553 2019
33
Cognitive and Motor Impairment Severity Related to Signs of Subclinical Wernicke's Encephalopathy in HIV Infection. 38
30958387 2019
34
Utility of Whole Blood Thiamine Pyrophosphate Evaluation in TPK1-Related Diseases. 38
31288420 2019
35
Thiamine dose response in human milk with supplementation among lactating women in Cambodia: study protocol for a double-blind, four-parallel arm randomised controlled trial. 38
31292183 2019
36
Thiamin Determination in Food: A Chromatographic Challenge (P13-038-19). 38
31225081 2019
37
Retrospective analysis of thiamine deficiency in allogeneic stem cell transplant patients. 38
30392066 2019
38
Overcoming the Current Challenges of Thiamine Deficiency Disorders (P10-091-19). 38
31225106 2019
39
The In Vivo and In Vitro Toxicokinetics of Citreoviridin Extracted from Penicillium citreonigrum. 38
31226823 2019
40
Loss of Vestibular Ocular Reflex in Nonconvulsive Status Epilepticus. 38
29951957 2019
41
Hyperemesis gravidarum causing Wernicke-Korsakoff syndrome: A rare complication. 38
31215137 2019
42
Thiamine Deficiency in People with Obesity (P18-060-19). 38
31225092 2019
43
Wernicke's Encephalopathy Accompanying Acute Axonal Polyneuropathy: A Case Report. 38
31223251 2019
44
Wernicke Encephalopathy-Clinical Pearls. 38
31171116 2019
45
Thiamine and Heart Failure: Challenging Cases of Modern-Day Cardiac Beriberi. 38
31193878 2019
46
Wernicke's encephalopathy in hyperemesis gravidarum: A systematic review. 38
30889425 2019
47
Thiamine deficiency in the bereaved after cancer-related spousal loss. 38
31104649 2019
48
Wernicke-Korsakoff syndrome: Focus on low-threshold diagnosis and prompt treatment in the primary care setting. 38
30823858 2019
49
Possible involvement of thiamine insufficiency in heart failure in the institutionalized elderly. 38
31138958 2019
50
Supplemental thiamine for the treatment of acute heart failure syndrome: a randomized controlled trial. 38
31060559 2019
51
A Case of Ascending Sensory Neuropathy Due to Acute Onset Thiamine Deficiency After Intragastric Balloon Placement. 38
31134479 2019
52
Prevalent Low Thiamine Status Among Adults Living in Seoul Metropolitan Area (South Korea). 38
30982440 2019
53
Effects of Chronic Voluntary Alcohol Drinking on Thiamine Concentrations, Endoplasmic Reticulum Stress, and Oxidative Stress in the Brain of Crossed High Alcohol Preferring Mice. 38
30972556 2019
54
Vertical nystagmus in Wernicke's encephalopathy: pathogenesis and role of central processing of information from the otoliths. 38
31028542 2019
55
Using clinical decision support through the electronic medical record to increase prescribing of high-dose parenteral thiamine in hospitalized patients with alcohol use disorder. 38
30797383 2019
56
Wernicke encephalopathy hearing loss and palinacousis. 38
30957373 2019
57
Myocardial dysfunction in relation to serum thiamine levels in children with diabetic ketoacidosis. 38
30862760 2019
58
Anticonvulsant effects of thiamine on pentylenetetrazole-induced seizure in mice. 38
28766407 2019
59
A Pivotal Role for Thiamine Deficiency in the Expression of Neuroinflammation Markers in Models of Alcohol-Related Brain Damage. 38
30589435 2019
60
Dry Beriberi Due to Thiamine Deficiency Associated with Peripheral Neuropathy and Wernicke's Encephalopathy Mimicking Guillain-Barré syndrome: A Case Report and Review of the Literature. 38
30862772 2019
61
Visual loss and optic neuropathy associated with Wernicke's encephalopathy in hyperemesis gravidarum. 38
31041282 2019
62
Vitamin D: part II; cod liver oil, ultraviolet radiation, and eradication of rickets. 38
30627846 2019
63
Acute flaccid paralysis: Do not forget beriberi neuropathy. 38
30569499 2019
64
Beriberi neuropathy in oncological setting. 38
30873682 2019
65
Complete recovery in Wernicke's encephalopathy complicating hyperemesis gravidarum. 38
30737323 2019
66
Telomere shortening in alcohol dependence: Roles of alcohol and acetaldehyde. 38
30466069 2019
67
Comparison of the Effects of Yokukansan and Yokukansankachimpihange on Glutamate Uptake by Cultured Astrocytes and Glutamate-Induced Excitotoxicity in Cultured PC12 Cells. 38
31263507 2019
68
Thiamine deficiency observed in a cancer patient's caregiver. 38
30696506 2019
69
[Bilateral loss of the horizontal vestibulo-ocular reflex in Wernicke encephalopathy - a specific and early clinical sign]. 38
30694522 2019
70
Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children and Adults. 38
31019473 2019
71
Thiamine Substitution in Alcohol Use Disorder: A Narrative Review of Medical Guidelines. 38
30897571 2019
72
Starvation-induced diplopia and weakness: a case of beriberi and Wernicke's encephalopathy. 38
30610031 2019
73
Shoshin Beriberi and Severe Accidental Hypothermia as Causes of Heart Failure in a 6-Year-Old Child: A Case Report and Brief Review of Literature. 38
30984730 2019
74
Evodiamine Augments NLRP3 Inflammasome Activation and Anti-bacterial Responses Through Inducing α-Tubulin Acetylation. 38
30971927 2019
75
Amprolium exposure alters mice behavior and metabolism in vivo. 38
30891577 2018
76
A review of micronutrients in sepsis: the role of thiamine, l-carnitine, vitamin C, selenium and vitamin D. 38
29984680 2018
77
Blood Thiamine Level and Cognitive Function in Older Hospitalized Patients. 38
30572755 2018
78
Non-alcoholic Wernicke encephalopathy: great masquerader. 38
30593527 2018
79
Brachytherapy of tongue carcinoma in a patient with difficult airway: anesthetic considerations. 38
30662482 2018
80
A Case of Wernicke Encephalopathy Developing After Ileal Bypass Surgery. 38
29596284 2018
81
Wernicke encephalopathy without delirium that appeared as agitation in a patient with lung cancer. 38
29747720 2018
82
Acute toxic encephalopathy induced by occupational exposure to 1,2-dichloropropane. 38
29973469 2018
83
Beriberi disease in an 11-year-old girl with total colectomy. 38
30397502 2018
84
Vitamin B1 for type B metabolic acidosis: An underrecognized approach. 38
30588982 2018
85
Isolated Mammillary Bodies Damage-An Atypical Presentation of Wernicke Syndrome. 38
30424509 2018
86
Wernicke's encephalopathy in a patient with non-Hodgkin's lymphoma post-Autologous HSCT. 38
30517233 2018
87
Thiamine status in end-stage chronic kidney disease patients: a single-center study. 38
30182293 2018
88
Thiamine Deficiency Induced Dietary Disparity Promotes Oxidative Stress and Neurodegeneration. 38
30319188 2018
89
Beriberi Outbreak Among Unauthorised Immigrants in a Detention Camp in Malaysia. 38
29159485 2018
90
Preventing Wernicke's encephalopathy in anorexia nervosa: A systematic review. 38
29984541 2018
91
Review of thiamine deficiency disorders: Wernicke encephalopathy and Korsakoff psychosis. 38
30281514 2018
92
Early detection and successful treatment of Wernicke's encephalopathy in outpatients without the complete classic triad of symptoms who attended a psycho-oncology clinic. 38
29478423 2018
93
Conversion of upbeat to downbeat nystagmus in Wernicke encephalopathy. 38
30348852 2018
94
Thiamine deficiency and cardiovascular disorders. 38
30143411 2018
95
Thiamine deficiency disorders: diagnosis, prevalence, and a roadmap for global control programs. 38
30151974 2018
96
Thiamine Deficiency: An Important Consideration in Critically Ill Patients. 38
30146080 2018
97
Thiamine deficiency contributes to synapse and neural circuit defects. 38
30231926 2018
98
Stabilization of the hypoxia-inducible transcription Factor-1 alpha (HIF-1α) in thiamine deficiency is mediated by pyruvate accumulation. 38
30008376 2018
99
Thiamine status, metabolism and application in dairy cows: a review. 38
29986774 2018
100
Thiamine Levels in Muscle and Eggs of Adult Pacific Salmon from the Fraser River, British Columbia. 38
29799640 2018
101
Thiaminase I Provides a Growth Advantage by Salvaging Precursors from Environmental Thiamine and Its Analogs in Burkholderia thailandensis. 38
30006396 2018
102
A single-step method for simultaneous quantification of thiamine and its phosphate esters in whole blood sample by ultra-performance liquid chromatography-mass spectrometry. 38
30056266 2018
103
Thiamine Prescribing and Wernicke's Encephalopathy Risk Factors in Patients With Alcohol Use Disorders at a Psychiatric Hospital. 38
30427818 2018
104
The 11th pitfall: thiamine deficiency. 38
29934922 2018
105
The Wrong Turn to Tijuana: Dry Beriberi after Gastric Bypass Surgery with Incidental Spinal Stenosis. 38
30519179 2018
106
Thalamic Proteome Changes and Behavioral Impairments in Thiamine-deficient Rats. 38
29894819 2018
107
Missing the early signs of thiamine deficiency. A case associated with a liquid-only diet. 38
30092713 2018
108
Subclinical thiamine deficiency in patients with abdominal cancer. 38
29277168 2018
109
Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy. 38
29860433 2018
110
Progressive supranuclear palsy responding to intravenous thiamine: superimposed Wernicke's encephalopathy? 38
30131406 2018
111
Wernicke's Encephalopathy. 38
30364782 2018
112
Wernicke encephalopathy in a lung cancer patient during treatment with nivolumab. 38
30073944 2018
113
Subclinical thiamine deficiency identified by preoperative evaluation in an ovarian cancer patient: Diagnosis and the need for preoperative thiamine measurement. 38
30168403 2018
114
Hairs in old books isotopically reconstruct the eating habits of early modern Japan. 38
30108372 2018
115
Clinical Characteristics and Outcomes Associated With High-Dose Intravenous Thiamine Administration in Patients With Encephalopathy. 38
29482863 2018
116
Prevalence and predictors of postoperative thiamine deficiency after vertical sleeve gastrectomy. 38
29803410 2018
117
Prevalence and predictors of postoperative thiamine deficiency after vertical sleeve gastrectomy. 38
29960866 2018
118
Wernicke Encephalopathy Due to Hyperemesis Gravidarum in Pregnancy: A Case Report. 38
30237950 2018
119
Impairment of Thiamine Transport at the GUT-BBB-AXIS Contributes to Wernicke's Encephalopathy. 38
29128903 2018
120
Gastrointestinal beriberi: a forme fruste of Wernicke's encephalopathy? 38
29982183 2018
121
The refeeding syndrome. Importance of phosphorus. 38
29448987 2018
122
Severe lactic acidosis in an extremely low birth weight infant due to thiamine deficiency. 38
29715193 2018
123
The role of thiamine dependent enzymes in obesity and obesity related chronic disease states: A systematic review. 38
29779823 2018
124
Wernicke's encephalopathy following reduced food intake due to depressive disorders. 38
28410563 2018
125
Thiamine and Cardiovascular Disease: A Literature Review. 38
29360523 2018
126
Wernicke's Encephalopathy as a Rare Complication of Hyperemesis Gravidarum: A Case Report and Review of Literature. 38
30013861 2018
127
Organic cation transporter 1 (OCT1) modulates multiple cardiometabolic traits through effects on hepatic thiamine content. 38
29659562 2018
128
Effect of blood thiamine concentrations on mortality: Influence of nutritional status. 38
29469010 2018
129
Thiamine diphosphate reduction strongly correlates with brain glucose hypometabolism in Alzheimer's disease, whereas amyloid deposition does not. 38
29490669 2018
130
Microglial activation and vascular responses that are associated with early thalamic neurodegeneration resulting from thiamine deficiency. 38
29427613 2018
131
Severe neurological complication following adjustable gastric banding. 38
29694308 2018
132
Wet Beriberi Associated with Hikikomori Syndrome. 38
29188542 2018
133
Wet beriberi with multiple organ failure remarkably reversed by thiamine administration: A case report and literature review. 38
29489643 2018
134
Metformin-induced encephalopathy: the role of thiamine. 38
29415360 2018
135
Wernicke encephalopathy without delirium in patients with cancer. 38
28464962 2018
136
Thiamine versus placebo in older heart failure patients: study protocol for a randomized controlled crossover feasibility trial (THIAMINE-HF). 38
30258648 2018
137
Oral High-Dose Thiamine Improves the Symptoms of Chronic Cluster Headache. 38
29850313 2018
138
Pathway Editing Targets for Thiamine Biofortification in Rice Grains. 38
30042775 2018
139
Fatty acid signatures connect thiamine deficiency with the diet of the Atlantic salmon (Salmo salar) feeding in the Baltic Sea. 38
30369636 2018
140
The medial vestibular nuclei, a vulnerable target in thiamine deficiency. 38
29143209 2018
141
Prevalence of thiamine deficiency in older hospitalized patients. 38
30464433 2018
142
Clinical Characteristics and Etiology of Bilateral Vestibular Loss in a Cohort from Central Illinois. 38
29545765 2018
143
Thiamin. 38
29477220 2018
144
Wernicke-Korsakoff syndrome complicated by subacute beriberi neuropathy in an alcoholic patient. 38
29128624 2018
145
Red Flags in the Assessment of Adult Ophthalmoplegia. 38
30196782 2018
146
Vestibular Dysfunction in Wernicke's Encephalopathy: Predominant Impairment of the Horizontal Semicircular Canals. 38
29593640 2018
147
Myocardial ischemia in an adolescent secondary to nutritional thiamine deficiency. 38
29686552 2018
148
Re-emergence of thiamine deficiency disease in the Pacific islands (2014-15): A case-control study. 38
29879174 2018
149
Post mortem findings and their relation to AA amyloidosis in free-ranging Herring gulls (Larus argentatus). 38
29494674 2018
150
A Patient With Thiamine Deficiency Exhibiting Muscle Edema Suggested by MRI. 38
30619043 2018
151
Occupational, physical, sexual and mental health and violence among migrant and trafficked commercial fishers and seafarers from the Greater Mekong Subregion (GMS): systematic review. 38
30288452 2018
152
Yeast caspase-dependent apoptosis in Saccharomyces cerevisiae BY4742 induced by antifungal and potential antitumor agent clotrimazole. 38
28819786 2018
153
Moradi H, Said HM. Functional thiamine deficiency in end-stage renal disease: malnutrition despite ample nutrients. Kidney Int. 2016;90:252-254. 38
29153143 2017
154
Expression of Thiaminase in Zebrafish (Danio rerio) is Lethal and Has Implications for Use as a Biocontainment Strategy in Aquaculture and Invasive Species. 38
28980193 2017
155
Are Psychiatric Inpatients at Risk of Developing Wernicke's Encephalopathy Being Identified and Adequately Treated? 38
29286589 2017
156
Epileptic seizures in nonalcoholic Wernicke's encephalopathy: a case report and literature review. 38
28875427 2017
157
[Wernicke-Korsakoff syndrome secondary to cytomegalovirus encephalitis: A case report]. 38
29373764 2017
158
A diagnosis and treatment gap for thiamine deficiency disorders in sub-Saharan Africa? 38
29064578 2017
159
The effect of subclinical infantile thiamine deficiency on motor function in preschool children. 38
28133900 2017
160
Progressive encephalopathy associated with nutritional deficiencies: Identifying patients at high risk for developing thiamine deficiency. 38
27693006 2017
161
Thiamine deficiency impairs common eider (Somateria mollissima) reproduction in the field. 38
29089512 2017
162
Vitamin B1 in critically ill patients: needs and challenges. 38
28432843 2017
163
Thiamine Levels During Intensive Insulin Therapy in Critically Ill Patients. 38
27440134 2017
164
Wernicke's encephalopathy in exclusive breastfed infants. 38
28540694 2017
165
Thiamine deficiency in childhood with attention to genetic causes: Survival and outcome predictors. 38
28856750 2017
166
High rate of thiamine deficiency among inpatients with cancer referred for psychiatric consultation: results of a single site prevalence study. 38
27228202 2017
167
Thiamine Deficiency and Neurodegeneration: the Interplay Among Oxidative Stress, Endoplasmic Reticulum Stress, and Autophagy. 38
27596507 2017
168
High prevalence of thiamine (vitamin B1) deficiency in early childhood among a nationally representative sample of Cambodian women of childbearing age and their children. 38
28873391 2017
169
Adolescent Bariatric Surgery and Thiamine Deficiency: What Do We Know So Far? 38
28771420 2017
170
Thiamine deficiency in metronidazole-induced encephalopathy: A metabolic correlation? 38
28716273 2017
171
A Concise History of Mycotoxin Research. 38
27960261 2017
172
The Study on the Lives and Health Conditions of Internees in Santo Thomas Camp of Philippines - Based on McAnlis's The War in Manila (1941-1945). 38
28919592 2017
173
Consideration of alternative causes of lactic acidosis: Thiamine deficiency in malignancy. 38
28539246 2017
174
Thiamine deficiency appears uncommon in patients with Myeloproliferative Neoplasms. 38
27135305 2017
175
Comparative effects of EtOH consumption and thiamine deficiency on cognitive impairment, oxidative damage, and β-amyloid peptide overproduction in the brain. 38
28342849 2017
176
Thiamine and benfotiamine prevent stress-induced suppression of hippocampal neurogenesis in mice exposed to predation without affecting brain thiamine diphosphate levels. 38
28506637 2017
177
Wernicke’s encephalopathy associated with liver abscess. 38
28765488 2017
178
Long-Term Mortality of Patients with an Alcohol-Related Wernicke-Korsakoff Syndrome. 38
28340112 2017
179
Nonalcoholic Wernicke's Encephalopathy: A Retrospective Study from a Tertiary Care Center in Northern India. 38
28694620 2017
180
Acute up-beating nystagmus in a pregnant woman with hyperemesis gravidarum. 38
29260066 2017
181
Lactic Acidosis as Presenting Symptom of Thiamine Deficiency in Children with Hematologic Malignancy. 38
31073437 2017
182
Nutrients and Neurology. 38
28570331 2017
183
Alcohol and thiamine deficiency trigger differential mitochondrial transition pore opening mediating cellular death. 38
28417285 2017
184
The Spectrum of Vestibular and Ocular Motor Abnormalities in Thiamine Deficiency. 38
28365885 2017
185
The influence of infantile thiamine deficiency on primary dentition. 38
27312377 2017
186
Fundus Findings in Wernicke Encephalopathy. 38
28924437 2017
187
Thiamine deficiency, oxidative metabolic pathways and ethanol-induced neurotoxicity: how poor nutrition contributes to the alcoholic syndrome, as Marchiafava-Bignami disease. 38
28225048 2017
188
A Large Outbreak of Thiamine Deficiency Among Illegal Gold Miners in French Guiana. 38
28500804 2017
189
Thiamine Deficiency Increases Ca2+ Current and CaV1.2 L-type Ca2+ Channel Levels in Cerebellum Granular Neurons. 38
27140189 2017
190
Cortical damage in Wernicke's encephalopathy with good prognosis: a report of two cases and literature review. 38
27734188 2017
191
Thiamine deficiency induces endoplasmic reticulum stress and oxidative stress in human neurons derived from induced pluripotent stem cells. 38
28193519 2017
192
Outbreak of thiamine deficiency in cats associated with the feeding of defective dry food. 38
26783020 2017
193
Thiamine Assays-Advances, Challenges, and Caveats. 38
28413748 2017
194
Bioactive Triterpenoids from the Twigs of Chaenomeles sinensis. 38
28358502 2017
195
Acute beriberi neuropathy mimicking Guillain-Barré syndrome after a strict vegetarian diet. 38
28761634 2017
196
Nutritional standards needed for ready meals to avoid micronutrient deficiencies. 38
28361624 2017
197
Chronic Ethanol Consumption and Thiamine Deficiency Modulate β-Amyloid Peptide Level and Oxidative Stress in the Brain. 38
28182200 2017
198
Dutch Research on Beriberi: I. Christiaan Eijkman's Research and Evaluation of Kanehiro Takaki's Diet Reforms of the Japanese Navy. 38
30549780 2017
199
Treatment of rats with the JAK-2 inhibitor fedratinib does not lead to experimental Wernicke's encephalopathy. 38
28109775 2017
200
Wernicke's Encephalopathy after Bariatric Surgery with Atypical Magnetic Resonance Imaging: A Case Report. 38
28752511 2017
201
[Thiamine (vitamin B1) treatment in patients with alcohol dependence]. 38
27818067 2017
202
Thiamine deficiency in cats. 38
28283638 2017
203
[From thiamine deficiency to Wernicke encephalopathy, unknown pathology]. 38
28708361 2017
204
BDNF regains function in hippocampal long-term potentiation deficits caused by diencephalic damage. 38
28096497 2017
205
Wernicke's encephalopathy mimicking neuropsychiatric symptoms in patients with systemic lupus erythematosus: a report of three cases and literature review. 38
27416844 2017
206
Thiamine deficiency activates hypoxia inducible factor-1α to facilitate pro-apoptotic responses in mouse primary astrocytes. 38
29045486 2017
207
The Dramatic Recovery of a Patient with Biguanide-associated Severe Lactic Acidosis Following Thiamine Supplementation. 38
28202871 2017
208
A novel encephalopathy in a thiamine-deficient dog resembling human Wernicke's disease with atypical MRI pattern. 38
29138746 2017
209
[Thiamine in patients with alcohol use disorder and Wernicke's encephalopathy]. 38
28224875 2017
210
High-dose Parenteral Thiamine in Treatment of Wernicke's Encephalopathy: Case Series and Review of the Literature. 38
28064230 2017
211
Illumina Sequencing Approach to Characterize Thiamine Metabolism Related Bacteria and the Impacts of Thiamine Supplementation on Ruminal Microbiota in Dairy Cows Fed High-Grain Diets. 38
28979254 2017
212
Delayed diagnosis of Wernicke encephalopathy with irreversible neural damage after subtotal gastrectomy for gastric cancer: A case of medical liability? 38
27988455 2017
213
Prevalence of clinical thiamine deficiency in individuals with medically complicated obesity. 38
28215312 2017
214
High-dose thiamine prevents brain lesions and prolongs survival of Slc19a3-deficient mice. 38
28665968 2017
215
[Wernicke encephalopathy and dry beriberi; late complications after bariatric surgery performed on a patient with a psychiatric history]. 38
28350154 2017
216
Korsakoff's syndrome: a critical review. 38
29225466 2017
217
Thiamine Deficiency Leading to Refractory Lactic Acidosis in a Pediatric Patient. 38
29119026 2017
218
B-cell lymphoma, thiamine deficiency, and lactic acidosis. 38
28127139 2017
219
Shoshin beriberi-thiamine responsive pulmonary hypertension in exclusively breastfed infants: A study from northern India. 38
28228301 2017
220
Visual Loss, Retinal Hemorrhages, and Optic Disc Edema Resulting From Thiamine Deficiency Following Bariatric Surgery Complicated by Prolonged Vomiting. 38
28331457 2017
221
Usefulness of central venous saturation as a predictor of thiamine deficiency in critically ill patients: a case report. 38
29142756 2017
222
No Camphor Toxicity in Cambodian Infants. 38
28491925 2017
223
Role of Green Tea Flavonoids and Other Related Contents in Cancer Prevention. 38
28845765 2017
224
The relationship between thiamine and two symbioses: Root nodule symbiosis and arbuscular mycorrhiza. 38
27977319 2016
225
Widespread episodic thiamine deficiency in Northern Hemisphere wildlife. 38
27958327 2016
226
Prevalence of thiamine deficiency in a stable heart failure outpatient cohort on standard loop diuretic therapy. 38
26923517 2016
227
Acute Abdominal Pain as a Presenting Symptom of Beriberi in a Pediatric Patient. 38
27329387 2016
228
Adjuvant thiamine improved standard treatment in patients with major depressive disorder: results from a randomized, double-blind, and placebo-controlled clinical trial. 38
26984349 2016
229
Brain endothelial dysfunction following pyrithiamine induced thiamine deficiency in the rat. 38
27984051 2016
230
Vitamin B1-deficient mice show impairment of hippocampus-dependent memory formation and loss of hippocampal neurons and dendritic spines: potential microendophenotypes of Wernicke-Korsakoff syndrome. 38
27576603 2016
231
Cobalt Cardiomyopathy: A Critical Reappraisal in Light of a Recent Resurgence. 38
27852654 2016
232
The Thiamine Biosynthesis Gene THI1 Promotes Nodule Growth and Seed Maturation. 38
27702844 2016
233
Long-term treatment with thiamine as possible medical therapy for Friedreich ataxia. 38
27488863 2016
234
Severe Infections are Common in Thiamine Deficiency and May be Related to Cognitive Outcomes: A Cohort Study of 68 Patients With Wernicke-Korsakoff Syndrome. 38
27498674 2016
235
[Beriberi 10 years after gastric bypass surgery - case report]. 38
27813489 2016
236
Wernicke Encephalopathy and Sleeve Gastrectomy: A Case Report and Literature Review. 38
26539904 2016
237
An unusual case of cardiogenic shock in which thiamine administration led to reversal of lactic acidosis and heart function recovery: Shoshin beriberi in an adolescent. 38
27505323 2016
238
Neuromyelitis optica spectrum disorders may be misdiagnosed as Wernicke's encephalopathy. 38
26287559 2016
239
Perinatal Consumption of Thiamine-Fortified Fish Sauce in Rural Cambodia: A Randomized Clinical Trial. 38
27532780 2016
240
Mammillary body volume abnormalities in anorexia nervosa. 38
27414055 2016
241
Wernicke's encephalopathy with chorea: Neuroimaging findings. 38
29213485 2016
242
Can long-term thiamine treatment improve the clinical outcomes of myotonic dystrophy type 1? 38
27857755 2016
243
Wernicke's Encephalopathy - 'Pushing the Envelope' of Patient's Profile: A Case Report. 38
27721589 2016
244
Alcoholic cardiomyopathy : The result of dosage and individual predisposition. 38
27582365 2016
245
Functional thiamine deficiency in end-stage renal disease: malnutrition despite ample nutrients. 38
27418090 2016
246
The uremic toxin oxythiamine causes functional thiamine deficiency in end-stage renal disease by inhibiting transketolase activity. 38
27198804 2016
247
Thiamine Deficiency in a Developed Country: Acute Lactic Acidosis in Two Neonates Due to Unsupplemented Parenteral Nutrition. 38
25591974 2016
248
Cranial Ultrasonography in Infantile Encephalitic Beriberi: A Useful First-Line Imaging Tool for Screening and Diagnosis in Suspected Cases. 38
27056426 2016
249
Polioencephalomalacia and Heart Failure Secondary to Presumptive Thiamine Deficiency, Hepatic Lipidosis, and Starvation in 2 Abandoned Siamese Cats. 38
26792845 2016
250
Metabolic resuscitation in sepsis: a necessary step beyond the hemodynamic? 38
27501325 2016
251
Clinical awareness for health care professionals: Fatal encephalopathy complicating persistent vomiting in pregnancy. 38
27499405 2016
252
Does Long-Term Furosemide Therapy Cause Thiamine Deficiency in Patients with Heart Failure? A Focused Review. 38
26899752 2016
253
Thiamine deficiency in the Western diet and dementia risk. 38
27170224 2016
254
Chronic Migraine Responding to Intravenous Thiamine: A Report of Two Cases. 38
27197607 2016
255
Nonalcoholic Wernicke's encephalopathy. 38
25985980 2016
256
Concomitants of alcoholism: differential effects of thiamine deficiency, liver damage, and food deprivation on the rat brain in vivo. 38
27129864 2016
257
Early detection and successful treatment of Wernicke encephalopathy in a patient with advanced carcinoma of the external genitalia during chemotherapy. 38
26653343 2016
258
Thiamine Deficiency Presenting as Intraventricular Hemorrhage. 38
27165958 2016
259
Perinatal thiamine deficiency causes cochlear innervation abnormalities in mice. 38
26944177 2016
260
[Clinical appearance and scalable profile Thiamine deficiency in prison in Guinea: study of thirty-eight observations]. 38
27100861 2016
261
A simple turn on fluorescent sensor for the selective detection of thiamine using coconut water derived luminescent carbon dots. 38
26745793 2016
262
Wernicke's encephalopathy in a patient with masticator and parapharyngeal space abscess: a case report. 38
27162754 2016
263
Wernicke's encephalopathy in crack-cocaine addiction. 38
26968913 2016
264
Wernicke's encephalopathy after total parenteral nutrition in patients with Crohn's disease. 38
27175122 2016
265
Exercise leads to the re-emergence of the cholinergic/nestin neuronal phenotype within the medial septum/diagonal band and subsequent rescue of both hippocampal ACh efflux and spatial behavior. 38
26836322 2016
266
Challenges in Diagnosis and Treatment of Wernicke Encephalopathy: Report of 2 Cases. 38
26869612 2016
267
Case report: pericardial effusion with constrictive physiology in a patient with wet beriberi. 38
27059308 2016
268
Bariatric Surgery and the Neuro-Ophthalmologist. 38
26764529 2016
269
Perinatal thiamine restriction affects central GABA and glutamate concentrations and motor behavior of adult rat offspring. 38
26836141 2016
270
Thiamine deficiency to ward off cardiovascular dysfunction and SUDEP: Yay or nay? 38
26828691 2016
271
Vitamin B1 (thiamine) and dementia. 38
26971083 2016
272
Randomized, Double-Blind, Placebo-Controlled Trial of Thiamine as a Metabolic Resuscitator in Septic Shock: A Pilot Study. 38
26771781 2016
273
Thiamine responsive acute life threatening metabolic acidosis in exclusively breast-fed infants. 38
26515900 2016
274
Commentary: Thiamine Deficiency in Tropical Pediatrics: New Insights into a Neglected but Vital Metabolic Challenge. 38
28138437 2016
275
Risk of thiamine deficiency and Wernicke's encephalopathy after gastrointestinal surgery for cancer. 38
25931232 2016
276
[Thiamine deficiency caused lactic acidosis in patient with malnutrition]. 38
26756341 2016
277
Infantile encephalitic beriberi: magnetic resonance imaging findings. 38
26286085 2016
278
Elevated Lactate Secondary to Gastrointestinal Beriberi. 38
25876741 2016
279
Thiamine Deprivation Produces a Liver ATP Deficit and Metabolic and Genomic Effects in Mice: Findings Are Parallel to Those of Biotin Deficiency and Have Implications for Energy Disorders. 38
28214879 2016
280
Beriberi Induced Cardiomyopathy Requiring Salvage Venoarterial Extracorporeal Membrane Oxygenation. 38
28050289 2016
281
Wernicke's Encephalopathy Complicating Hyperemesis during Pregnancy. 38
26989522 2016
282
Severe Acute Axonal Neuropathy following Treatment with Arsenic Trioxide for Acute Promyelocytic Leukemia: a Case Report. 38
27158436 2016
283
Nonalcoholic Thiamine-Related Encephalopathy (Wernicke-Korsakoff Syndrome) Among Inpatients With Cancer: A Series of 18 Cases. 38
26791514 2016
284
Thiamine Deficiency in Tropical Pediatrics: New Insights into a Neglected but Vital Metabolic Challenge. 38
27379239 2016
285
Determining the Role of Thiamine Deficiency in Systolic Heart Failure: A Meta-Analysis and Systematic Review. 38
26497757 2015
286
Critical period for first language: the crucial role of language input during the first year of life. 38
26111432 2015
287
Serum Thiamine Values in End-Stage Renal Disease Patients under Maintenance Hemodialysis. 38
27164172 2015
288
Enhancement of Thiamin Content in Arabidopsis thaliana by Metabolic Engineering. 38
26454882 2015
289
Wernicke-Korsakoff syndrome not related to alcohol use: a systematic review. 38
25589780 2015
290
Sudden infant death syndrome and abnormal metabolism of thiamin. 38
26455416 2015
291
A Rare Complication Developing After Hematopoietic Stem Cell Transplantation: Wernicke's Encephalopathy. 38
25912759 2015
292
Wernicke's encephalopathy following Roux en Y gastric bypass surgery. 38
26620994 2015
293
High-Output Heart Failure Caused by Thyrotoxicosis and Beriberi. 38
26567494 2015
294
Interactions between chronic ethanol consumption and thiamine deficiency on neural plasticity, spatial memory, and cognitive flexibility. 38
26419807 2015
295
Beriberi: an uncommon complication of sleeve gastrectomy. 38
26499354 2015
296
A non-alcoholic Wernicke's encephalopathy case with atypical MRI findings: Clinic versus radiology. 38
26306933 2015
297
[An Uncommon Diagnosis]. 38
26463907 2015
298
Bilateral Blindness Following Chemoradiation for Locally Advanced Oropharyngeal Carcinoma. 38
26623207 2015
299
[THIAMINE--"THE ROAD EXPERIENCE" OF THE VITAMIN AS A MANIFESTATION OF DEFICIENCY IN A WORLD OF ABUNDANCE]. 38
26742231 2015
300
Palliative treatment of thiamine-related encephalopathy (Wernicke's encephalopathy) in cancer: A case series and review of the literature. 38
25339378 2015
301
Endoplasmic Reticulum Stress and Ethanol Neurotoxicity. 38
26473940 2015
302
Thiamine deficiency in amyotrophic lateral sclerosis. 38
25901033 2015
303
A Therapeutic Fast for Lymphoma Resulting in Wernicke Encephalopathy. 38
26104844 2015
304
Nerve Fiber Layer Infarcts in Thiamine Deficiency. 38
25815858 2015
305
[The role of thiamine in neurodegenerative diseases]. 38
26400895 2015
306
Influence of intravenous thiamine supplementation on blood lactate concentration prior to cardiac surgery: A double-blinded, randomised controlled pilot study. 38
26066773 2015
307
Reversal of severe lactic acidosis with thiamine in a renal allograft recipient. 38
26180438 2015
308
Thiamine Deficiency-Mediated Brain Mitochondrial Pathology in Alaskan Huskies with Mutation in SLC19A3.1. 38
25117056 2015
309
Dry beriberi preceded Wernicke's encephalopathy: Thiamine deficiency after laparoscopic sleeve gastrectomy. 38
26557183 2015
310
Encephalopathy caused by thiamine deficiency. 38
26447243 2015
311
An asymmetric sensory polyneuropathy related to thiamine deficiency from a gluten-free diet. 38
25996970 2015
312
Procedural Learning and Memory Rehabilitation in Korsakoff's Syndrome - a Review of the Literature. 38
26047664 2015
313
Encephalopathy after persistent vomiting: Three cases of non-alcohol-related Wernicke's encephalopathy. 38
26716155 2015
314
Memory dysfunction. 38
26039844 2015
315
Iatrogenic Wernicke encephalopathy in a patient with severe hyperemesis gravidarum. 38
25774927 2015
316
Hypomagnesaemia and its potential impact on thiamine utilisation in patients with alcohol misuse at the Alice Springs Hospital. 38
25693730 2015
317
Spatial cognitive deficits in an animal model of Wernicke-Korsakoff syndrome are related to changes in thalamic VDAC protein concentrations. 38
25766938 2015
318
Metabolic acidosis during parenteral nutrition: Pathophysiological mechanisms. 38
25983433 2015
319
Shoshin Beriberi in Critically-Ill patients: case series. 38
25982313 2015
320
Thiamine prescribing practices within university-affiliated hospitals: a multicenter retrospective review. 38
25652810 2015
321
Beriberi in Cambodia. 38
25837026 2015
322
CROSSTALK BETWEEN VITAMIN B AND IMMUNITY. 38
26122215 2015
323
Electrical properties of isolated cardiomyocytes in a rat model of thiamine deficiency. 38
25884771 2015
324
Poor thiamin and riboflavin status is common among women of childbearing age in rural and urban Cambodia. 38
25733481 2015
325
Beriberi (thiamine deficiency) and high infant mortality in northern Laos. 38
25781926 2015
326
Clinicopathologic features of folate-deficiency neuropathy. 38
25663227 2015
327
Comprehensive assessment of alcohol-related brain damage (ARBD): gap or chasm in the evidence? 38
24846298 2015
328
Thiamine deficiency: an update of pathophysiologic mechanisms and future therapeutic considerations. 38
25297573 2015
329
Rapid reversal of severe lactic acidosis after thiamine administration in critically ill adults: a report of 3 cases. 38
25516536 2015
330
Low thiamine levels in children with type 1 diabetes and diabetic ketoacidosis: a pilot study. 38
25560422 2015
331
Thiamine and magnesium deficiencies: keys to disease. 38
25542071 2015
332
Vitamin B status in patients with type 2 diabetes mellitus with and without incipient nephropathy. 38
25458341 2015
333
An unusual cause of persisting hyperlactatemia in a neonate undergoing open heart surgery. 38
25548361 2015
334
PKR downregulation prevents neurodegeneration and β-amyloid production in a thiamine-deficient model. 38
25590804 2015
335
Biochemical changes correlated with blood thiamine and its phosphate esters levels in patients with diabetes type 1 (DMT1). 38
26722561 2015
336
Thiamine deficiency: a cause of profound hypotension and hypothermia after plastic surgery. 38
25568246 2015
337
Commentary on: Thiamine deficiency: a cause of profound hypotension and hypothermia after plastic surgery. 38
25568251 2015
338
Mild thiamine deficiency and chronic ethanol consumption modulate acetylcholinesterase activity change and spatial memory performance in a water maze task. 38
24770900 2015
339
The role of ventral midline thalamus in cholinergic-based recovery in the amnestic rat. 38
25446352 2015
340
Type B lactic acidosis secondary to thiamine deficiency in a child with malignancy. 38
25548327 2015
341
Shoshin Beriberi With Low Cardiac Output and Hemodynamic Deterioration Treated Dramatically by Thiamine Administration. 38
26346515 2015
342
Beriberi in Cambodia. 38
26744150 2015
343
Wernicke's Encephalopathy, Wet Beriberi, and Polyneuropathy in a Patient with Folate and Thiamine Deficiency Related to Gastric Phytobezoar. 38
26697247 2015
344
Fortification and health: challenges and opportunities. 38
25593151 2015
345
Thiamine deficiency in tachypnoeic Cambodian infants. 38
26744155 2015
346
Purification and full characterisation of citreoviridin produced by Penicillium citreonigrum in yeast extract sucrose (YES) medium. 38
25190053 2015
347
[Experimental Approach to Analysis of the Relationship between Food Environments and Lifestyle-Related Diseases, Including Cardiac Hypertrophy, Fatty Liver, and Fatigue Symptoms]. 38
25994341 2015
348
Role of astrocytes in thiamine deficiency. 38
24929329 2014
349
Wernicke encephalopathy in pediatric neuro-oncology: presentation of 2 cases and review of literature. 38
24293308 2014
350
Deciphering regulatory variation of THI genes in alcoholic fermentation indicate an impact of Thi3p on PDC1 expression. 38
25494835 2014
351
Interactions of endoplasmic reticulum and mitochondria Ca(2+) stores with capacitative calcium entry. 38
24748364 2014
352
Mechanisms of hepatic encephalopathy and thiamine deficiency. 38
24972879 2014
353
[Nutrition and dietary supplements in psychiatric diseases]. 38
25421417 2014
354
Wernicke encephalopathy due to thiamine deficiency after surgery on a child with duodenal stenosis. 38
25303868 2014
355
Need for early diagnosis of mental and mobility changes in Wernicke encephalopathy. 38
25539041 2014
356
Diagnosis of reversible causes of coma. 38
24767707 2014
357
Response to Comment on "Thiamine deficiency promotes T cell infiltration in experimental autoimmune encephalomyelitis: the involvement of CCL2". 38
25381355 2014
358
Comment on "Thiamine deficiency promotes T cell infiltration in experimental autoimmune encephalomyelitis: the involvement of CCL2". 38
25381354 2014
359
Severe lactic acidosis in a diabetic patient after ethanol abuse and floor cleaner intake. 38
24717115 2014
360
[Wernicke's encephalopathy following sleeve gastrectomy for morbid obesity]. 38
24612868 2014
361
Associations between in vivo neuroimaging and postmortem brain cytokine markers in a rodent model of Wernicke's encephalopathy. 38
24973622 2014
362
Infant botulism: is there an association with thiamine deficiency? 38
25311602 2014
363
A case of shoshin beriberi presenting as cardiogenic shock with diffuse ST-segment elevation, which dramatically improved after a single dose of thiamine. 38
25625639 2014
364
Thiamine deficiency in tachypnoeic Cambodian infants. 38
25348055 2014
365
The Janus kinase 2 inhibitor fedratinib inhibits thiamine uptake: a putative mechanism for the onset of Wernicke's encephalopathy. 38
25063672 2014
366
Wernicke's encephalopathy in a malnourished surgical patient: a difficult diagnosis. 38
25312751 2014
367
Thiamine deficiency promotes T cell infiltration in experimental autoimmune encephalomyelitis: the involvement of CCL2. 38
25063874 2014
368
Thiamine deficiency in stem cell transplant patients: a case series with an accompanying review of the literature. 38
25486948 2014
369
Thiamine in the treatment of Wernicke encephalopathy in patients with alcohol use disorders. 38
25201422 2014
370
[Two cases of Wernicke´s encephalopathy that developed during total parenteral nutrition in colon cancer patients treated with 5-fluorouracil-based chemotherapy]. 38
25252865 2014
371
High-dose thiamine improves fatigue after stroke: a report of three cases. 38
25192035 2014
372
Wernicke's encephalopathy three weeks after sleeve gastrectomy. 38
24582417 2014
373
[Aortic thrombosis in a calf]. 38
25183676 2014
374
Thiamine deficiency in infancy: long-term follow-up. 38
25160536 2014
375
Acute thiamine deficiency and refeeding syndrome: Similar findings but different pathogenesis. 38
24985016 2014
376
Thiamine deficiency: the importance of recognition and prompt management. 38
24725734 2014
377
Wernicke encephalopathy in subjects undergoing restrictive weight loss surgery: a systematic review of literature data. 38
24764323 2014
378
OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin. 38
24961373 2014
379
[Sun Simiao's voyage to Chu and Shu regions]. 38
25429884 2014
380
[Sometimes they come back! A case of Shoshin Beriberi in Northern Italy (2012)]. 38
25072547 2014
381
Small-fiber degeneration in alcohol-related peripheral neuropathy. 38
24961481 2014
382
Defects of thiamine transport and metabolism. 38
24789339 2014
383
Thiamine deficiency secondary to anorexia nervosa: an uncommon cause of peripheral neuropathy and Wernicke encephalopathy in adolescence. 38
24938142 2014
384
Neurologic complications of bariatric surgery. 38
24893235 2014
385
Evidence for altered thiamine metabolism in diabetes: Is there a potential to oppose gluco- and lipotoxicity by rational supplementation? 38
24936250 2014
386
Severe lactic acidosis and multiorgan failure due to thiamine deficiency during total parenteral nutrition. 38
24895398 2014
387
Thiamine deficiency results in release of soluble factors that disrupt mitochondrial membrane potential and downregulate the glutamate transporter splice-variant GLT-1b in cultured astrocytes. 38
24735535 2014
388
Christmas Island over 100 years: from beriberi to nutritional deficiencies of a different kind. 38
24890491 2014
389
Thiamine deficiency and cardiac dysfunction in Cambodian infants. 38
24607240 2014
390
In vitro immune functions in thiamine-replete and -depleted lake trout (Salvelinus namaycush). 38
24680830 2014
391
Thiamine deficiency induces anorexia by inhibiting hypothalamic AMPK. 38
24607345 2014
392
Acute dilated cardiomyopathy in a patient with beriberi and cryoglobulinaemic vasculitis: an unusual potential complication of two rare disorders. 38
24429381 2014
393
Serum thiamine concentration and oxidative stress as predictors of mortality in patients with septic shock. 38
24412011 2014
394
Genetic implication of a novel thiamine transporter in human hypertension. 38
24509276 2014
395
Rasagiline prevents neurodegeneration in thiamine deficient rats-a longitudinal MRI study. 38
24525144 2014
396
Analysis of thiamine transporter genes in sporadic beriberi. 38
24607307 2014
397
[Thiamine deficiency in infants: a case report]. 38
24636593 2014
398
Thiamine and Hashimoto's thyroiditis: a report of three cases. 38
24351023 2014
399
Pyrithiamine-induced thiamine deficiency alters proliferation and neurogenesis in both neurogenic and vulnerable areas of the rat brain. 38
24078061 2014
400
Focal thalamic degeneration from ethanol and thiamine deficiency is associated with neuroimmune gene induction, microglial activation, and lack of monocarboxylic acid transporters. 38
24117525 2014
401
[Wernicke's encephalopathy induced by the use of diet pills and unbalanced diet]. 38
24631935 2014
402
Wernicke's encephalopathy following hyperemesis gravidarum. 38
24701066 2014
403
Current aspects of thiamine deficiency on heart function. 38
24398040 2014
404
Thiamine deficiency leads to reduced nitric oxide production and vascular dysfunction in rats. 38
24103804 2014
405
The relationship between lactate and thiamine levels in patients with diabetic ketoacidosis. 38
23993771 2014
406
Wernicke-Korsakoff syndrome in a patient with self-neglect associated with severe depression. 38
25057374 2014
407
Diagnosis and management of Marchiafava-Bignami disease: a review of CT/MRI confirmed cases. 38
23978380 2014
408
Thiamine deficiency in self-induced refeeding syndrome, an undetected and potentially lethal condition. 38
25614745 2014
409
The effect of thiamine deficiency on inflammation, oxidative stress and cellular migration in an experimental model of sepsis. 38
24826081 2014
410
Downregulation of transketolase activity is related to inhibition of hippocampal progenitor cell proliferation induced by thiamine deficiency. 38
25028661 2014
411
Molecular and neurologic responses to chronic alcohol use. 38
25307574 2014
412
Metabolic Benefits of Six-month Thiamine Supplementation in Patients With and Without Diabetes Mellitus Type 2. 38
24550684 2014
413
Analysis of thiamine concentrations in commercial canned foods formulated for cats. 38
24378026 2014
414
Neuropathology of alcoholism. 38
25307599 2014
415
Visual loss and optic nerve head swelling in thiamine deficiency without prolonged dietary deficiency. 38
24899800 2014
416
Differential cortical neurotrophin and cytogenetic adaptation after voluntary exercise in normal and amnestic rats. 38
24215977 2014
417
Prescribing thiamine to inpatients with alcohol use disorders: how well are we doing? 38
24343128 2014
418
Beriberi, a severe complication after metabolic surgery - review of the literature. 38
25095897 2014
419
The Montreal Cognitive Assessment (MoCA) is superior to the Mini Mental State Examination (MMSE) in detection of Korsakoff's syndrome. 38
25249353 2014
420
Chaenomeles speciosa: A review of chemistry and pharmacology. 38
24649061 2014
421
Human alcohol-related neuropathology. 38
24370929 2014
422
Total parenteral nutrition caused Wernicke's encephalopathy accompanied by wet beriberi. 38
24516692 2014
423
Shoshin beriberi induced by long-term administration of diuretics: a case report. 38
25105030 2014
424
Clinical history and colliquative myocytolysis are keys to the diagnosis of shoshin beriberi. 38
24891966 2014
425
Antiplatelet Activity of Morus alba Leaves Extract, Mediated via Inhibiting Granule Secretion and Blocking the Phosphorylation of Extracellular-Signal-Regulated Kinase and Akt. 38
24701244 2014
426
Vestibular signs of thiamine deficiency during the early phase of suspected Wernicke encephalopathy. 38
30107022 2013
427
Thiamine deficiency induces massive cell death in the olfactory bulbs of mice. 38
24226264 2013
428
Biomarkers of delirium as a clue to diagnosis and pathogenesis of Wernicke-Korsakoff syndrome. 38
23790077 2013
429
Double-blind, randomized placebo-controlled clinical trial of benfotiamine for severe alcohol dependence. 38
23992649 2013
430
Isolated mammillary body involvement on MRI in Wernicke's encephalopathy. 38
23953677 2013
431
Clinical evaluation and biochemical analyses of thiamine deficiency in Pacific harbor seals (Phoca vitulina) maintained at a zoological facility. 38
24094267 2013
432
[Vitamin B1 (thiamine)]. 38
24298824 2013
433
Treatable Leigh-like encephalopathy presenting in adolescence. 38
24099834 2013
434
"Dry" and "wet" beriberi mimicking critical illness polyneuropathy. 38
24339610 2013
435
Thiamine and its phosphate esters in relation to cardiometabolic risk factors in Saudi Arabs. 38
24059534 2013
436
Autophagy alleviates neurodegeneration caused by mild impairment of oxidative metabolism. 38
23586593 2013
437
Thiamine deficiency induces oxidative stress in brain mitochondria of Mus musculus. 38
23417786 2013
438
Thiamine deficiency in dogs and cats. 38
23971844 2013
439
Use of central venous saturation monitoring in a patient with pediatric cardiac beriberi. 38
24303502 2013
440
Altered and unstable: wet beriberi, a clinical review. 38
23849362 2013
441
Thiamine deficiency, beriberi, and maternal and child health: why pharmacokinetics matter. 38
23902781 2013
442
Thiamine pharmacokinetics in Cambodian mothers and their breastfed infants. 38
23864540 2013
443
High-dose thiamine as initial treatment for Parkinson's disease. 38
23986125 2013
444
Kanehiro Takaki and the control of beriberi in the Japanese Navy. 38
23897451 2013
445
A case of cardiac beriberi: a forgotten but memorable disease. 38
24044018 2013
446
Thiamine and fatigue in inflammatory bowel diseases: an open-label pilot study. 38
23379830 2013
447
Therapeutic benefits of an oral vitamin B1 derivative for human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). 38
23945332 2013
448
Thiamine supplementation for the treatment of heart failure: a review of the literature. 38
23910704 2013
449
The role of thiamine in cancer: possible genetic and cellular signaling mechanisms. 38
23893925 2013
450
Abnormal thiamine-dependent processes in Alzheimer's Disease. Lessons from diabetes. 38
22982063 2013
451
High dose thiamine improves fatigue in multiple sclerosis. 38
23861280 2013
452
[Case report: a case in which vitamin B1 was effective for treatment of shoshin beriberi and Wernicke's encephalopathy]. 38
23947241 2013
453
Clupeid response to stressors: the influence of environmental factors on thiaminase expression. 38
23560604 2013
454
High-dose thiamine improves the symptoms of fibromyalgia. 38
23696141 2013
455
Severe subacute necrotizing encephalopathy (Leigh-like syndrome) in American Staffordshire bull terrier dogs. 38
23123128 2013
456
A novel scoring system to guide risk assessment of Wernicke's encephalopathy. 38
23278769 2013
457
High-dose thiamine improves the symptoms of Friedreich's ataxia. 38
23704441 2013
458
Are brain and heart tissue prone to the development of thiamine deficiency? 38
23357554 2013
459
The role of thiamine in HIV infection. 38
23274124 2013
460
[Diagnostics and treatment of Wernicke-Korsakoff syndrome patients with an alcohol abuse]. 38
23582065 2013
461
Thiamine deficiency and delirium. 38
23696956 2013
462
The impact of oxidative stress in thiamine deficiency: a multifactorial targeting issue. 38
23333339 2013
463
Beriberi in a dialysis patient: do we need more thiamine? 38
23399344 2013
464
Thiamine deficiency following umbilical cord blood transplant. 38
23239794 2013
465
An unlikely culprit--the many guises of thiamine deficiency. 38
23380130 2013
466
Thiamine deficiency and its correlation with dyslipidaemia in diabetics with microalbuminuria. 38
23914634 2013
467
Perinatal thiamine deficiency-induced spontaneous abortion and pup-killing responses in rat dams. 38
22889588 2013
468
A case of Shoshin Beriberi: lessons old and new for the psychiatrist. 38
22658327 2013
469
Adolphe Vorderman's 1897 study on beriberi: an example of scrupulous efforts to avoid bias. 38
23481433 2013
470
Thiamine-deficient optic neuropathy associated with Wernicke's encephalopathy in patients with chronic diarrhea. 38
23473530 2013
471
Inducible intrapulmonary arteriovenous shunt in a patient with beriberi heart. 38
23378443 2013
472
An eating disorder leading to wet beriberi heart failure in a 30-year-old woman. 38
23158607 2013
473
Constipation in patients with thiamine deficiency after Roux-en-Y gastric bypass surgery. 38
23970020 2013
474
Clinical signs, MRI features, and outcomes of two cats with thiamine deficiency secondary to diet change. 38
23820206 2013
475
Preventing long-term brain damage in alcohol-dependent patients. 38
23427626 2013
476
Effects of thiamine on cardiac function in patients with systolic heart failure: systematic review and metaanalysis of randomized, double-blind, placebo-controlled trials. 38
24357996 2013
477
The connection between maternal thiamine shortcoming and offspring cognitive damage and poverty perpetuation in underprivileged communities across the world. 38
23098375 2013
478
[Neurology in Japan before World War II]. 38
24291835 2013
479
Alcohol-related dementia: an update of the evidence. 38
23347747 2013
480
Wernicke's encephalopathy that developed during the introduction period of peritoneal dialysis. 38
24042519 2013
481
Thiamine deficiency induced neurochemical, neuroanatomical, and neuropsychological alterations: a reappraisal. 38
24235882 2013
482
[Wernicke encephalopathy and Korsakoff's psychosis: clinical-pathophysiological correlation, diagnostics and treatment]. 38
23887463 2013
483
HIF1-α-mediated gene expression induced by vitamin B1 deficiency. 38
24846908 2013
484
Thiamine-responsive pulmonary hypertension. 38
23302552 2013
485
Erythrocyte transketolase activity in patients with diabetic and alcoholic neuropathies. 38
24114639 2013
486
Thiamine and spinocerebellar ataxia type 2. 38
23314445 2013
487
Oyaksungisan, a Traditional Herbal Formula, Inhibits Cell Proliferation by Induction of Autophagy via JNK Activation in Human Colon Cancer Cells. 38
23573119 2013
488
Parenteral nutrition additive shortages: the short-term, long-term and potential epigenetic implications in premature and hospitalized infants. 38
23223000 2012
489
Blood thiamine and its phosphate esters as measured by high-performance liquid chromatography: levels and associations in diabetes mellitus patients with varying degrees of microalbuminuria. 38
22107884 2012
490
[Lactic acidosis due to thiamine deficiency]. 38
22841461 2012
491
Impact of thiamine deficiency on T-cell dependent and T-cell independent antibody production in lake trout. 38
23134222 2012
492
One hundred years of vitamins-a success story of the natural sciences. 38
23208776 2012
493
Skin manifestations of nutritional deficiency disease in children: modern day contexts. 38
23171006 2012
494
Evolution of abnormal eye movements in Wernicke's encephalopathy: correlation with serial MRI findings. 38
22940074 2012
495
Non-alcoholic acute Wernicke's encephalopathy: role of MRI in non typical cases. 38
22954409 2012
496
Nystagmus: an uncommon neurological manifestation of thiamine deficiency as a serious complication of sleeve gastrectomy. 38
23042832 2012
497
Paradoxical effects of alcohol and thiamine deficiency on the eye opening in rat pups. 38
22716186 2012
498
Thiamine deficiency after bariatric surgery may lead to Wernicke encephalopathy. 38
23240377 2012
499
Serial evaluation of children with ALF with advanced MRI, serum proinflammatory cytokines, thiamine, and cognition assessment. 38
22614112 2012
500
Thiamine deficiency in Cambodian infants with and without beriberi. 38
22703952 2012
501
Wernicke-Korsakoff-syndrome: under-recognized and under-treated. 38
23157990 2012
502
Wernicke's encephalopathy presenting as acute psychosis after gastric bypass. 38
19406605 2012
503
Wernicke's encephalopathy and anabolic steroid drug abuse. Is there any possible relation? 38
23935320 2012
504
The discovery of the vitamins. 38
23798048 2012
505
Beriberi disease: is it still present in the United States? 38
22800868 2012
506
Case of beriberi showing improved cerebral blood flow after thiamine treatment. 38
22998382 2012
507
Clinical correlates and outcome of shoshin beriberi. 38
23112976 2012
508
[Occupational toxic neuropathies: morphology in peripheral nerve biopsies]. 38
23477107 2012
509
Thiamine deficiency: a viable hypothesis for paralytic syndrome in Baltic birds. Commentary on Sonne et al., 2012. A review of the factors causing paralysis in wild birds: implications for the paralytic syndrome observed in the Baltic Sea. Science of the Total Environment 416:32-39. 38
22818912 2012
510
Thiamine deficiency in vitro accelerates A-type potassium current inactivation in cerebellar granule neurons. 38
22771620 2012
511
Effects of thiamine deficiency on food intake and body weight increment in adult female and growing rats. 38
22854308 2012
512
Two cases of Wernicke's encephalopathy in young age patients receiving allogeneic hematopoietic stem cell transplantation. 38
22869492 2012
513
Wernicke's encephalopathy complicating hyperemesis gravidarum: from the background to the present. 38
22003959 2012
514
[Wernicke's encephalopathy associated with pellagra encephalopathy: rare and unusual complication in an elderly woman hospitalized for aspiration pneumonia]. 38
22703872 2012
515
Effects of dietary vitamin B₁ (thiamine) and magnesium on the survival, growth and histological indicators in lake trout (Salvelinus namaycush) juveniles. 38
22456309 2012
516
Thiamine deficiency degrades the link between spatial behavior and hippocampal synapsin I and phosphorylated synapsin I protein levels. 38
22507301 2012
517
Dry Beriberi and Wernicke's encephalopathy following gastric lap band surgery. 38
22525460 2012
518
Thiamine deficiency related microstructural brain changes in acute and acute-on-chronic liver failure of non-alcoholic etiology. 38
22172599 2012
519
Micronutrient status in lactating mothers before and after introduction of fortified flour: cross-sectional surveys in Maela refugee camp. 38
21786020 2012
520
The evolution and treatment of Korsakoff's syndrome: out of sight, out of mind? 38
22569770 2012
521
Wernicke's encephalopathy induced by hyperemesis gravidarum. 38
22684836 2012
522
Translational rodent models of Korsakoff syndrome reveal the critical neuroanatomical substrates of memory dysfunction and recovery. 38
22528861 2012
523
Wernicke's encephalopathy in a patient with acute pancreatitis: unusual cortical involvement and marvelous prognosis. 38
21918877 2012
524
Efficacy of adding folic acid to foods. 38
23258398 2012
525
Neuroimaging of Wernicke's encephalopathy and Korsakoff's syndrome. 38
22577003 2012
526
Implicit memory in Korsakoff's syndrome: a review of procedural learning and priming studies. 38
22592661 2012
527
[Clinical application of neuroimaging to alcohol-related dementia]. 38
22894053 2012
528
Glucose before thiamine for Wernicke encephalopathy: a literature review. 38
22104258 2012
529
[Polyneuropathies of pregnancy and the postpartum period in Burkina Faso]. 38
22982521 2012
530
Sustaining high acetylcholine levels in the frontal cortex, but not retrosplenial cortex, recovers spatial memory performance in a rodent model of diencephalic amnesia. 38
22448856 2012
531
Alcoholic neuropathy: possible mechanisms and future treatment possibilities. 38
21988193 2012
532
[Wernicke's encephalopathy as a complication of bariatric surgery]. 38
23088081 2012
533
Thiamine supplementation in symptomatic chronic heart failure: a randomized, double-blind, placebo-controlled, cross-over pilot study. 38
22057652 2012
534
Mechanisms of ethanol-induced death of cerebellar granule cells. 38
20927663 2012
535
Case report of acute thiamine deficiency occurring as a complication of vitamin-free parenteral nutrition. 38
22227728 2012
536
Dry beriberi mimicking Guillain-Barre syndrome as the first presenting sign of thiamine deficiency. 38
22136604 2012
537
[Shoshin beriberi: new emergence of an old pathology? About with 11 cases on island Mayotte]. 38
22170407 2012
538
Brain and behavioral pathology in an animal model of Wernicke's encephalopathy and Wernicke-Korsakoff Syndrome. 38
22192411 2012
539
Neurological complications in hyperemesis gravidarum. 38
21720901 2012
540
Thiamine in nutrition therapy. 38
22223666 2012
541
Thiamine-deficient infant formula: what happened and what have we learned? 38
22699764 2012
542
Thiamine diphosphate in whole blood, thiamine and thiamine monophosphate in breast-milk in a refugee population. 38
22768031 2012
543
Atypical case of Wolfram syndrome revealed through targeted exome sequencing in a patient with suspected mitochondrial disease. 38
22226368 2012
544
The historical evolution of thought regarding multiple micronutrient nutrition. 38
22157539 2012
545
[Life-threatening complication of schizophrenia]. 38
22252595 2012
546
Wernicke encephalopathy presenting in a patient with severe acute pancreatitis. 38
22233960 2012
547
Increase of serum vascular endothelial growth factors in wet beriberi: two case reports. 38
22504253 2012
548
[Beriberi after bariatric surgery]. 38
22727224 2012
549
[Anti-heat shock protein 70 (anti - Hsp 70) antibodies in alcohol use disorder patients]. 38
23421033 2012
550
Auditory system dysfunction due to infantile thiamine deficiency: long-term auditory sequelae. 38
22739497 2012
551
Thiamin(e): the spark of life. 38
22116701 2012
552
Subacute myelo‑optic neuropathy, beriberi, and HTLV‑I‑associated myelopathy: elucidation of some neurological diseases in Japan. 38
23222550 2012
553
The discovery of thiamin. 38
23183292 2012
554
Co-occurrence of aflatoxins B₁, B₂, G₁ and G₂, ochratoxin A, zearalenone, deoxynivalenol, and citreoviridin in rice in Brazil. 38
22316345 2012
555
The discovery of niacin, biotin, and pantothenic acid. 38
23183297 2012
556
Subacute gestational neuropathy: role of thiamine deficiency. 38