MCID: BTG003
MIFTS: 10

Beta-Glucopyranoside Tasting

Categories: Genetic diseases

Aliases & Classifications for Beta-Glucopyranoside Tasting

MalaCards integrated aliases for Beta-Glucopyranoside Tasting:

Name: Beta-Glucopyranoside Tasting 57 6
Beta-Glycopyranoside Tasting , (3) Alcohol Dependence, Susceptibility to 57
Beta-Glycopyranoside Tasting , (3) Alcohol Dependence 57

Characteristics:

OMIM:

57
Inheritance:
autosomal dominant

Miscellaneous:
most populations outside of africa carry the derivative allele that confers increased sensitivity to bitter taste


Classifications:



External Ids:

OMIM 57 617956

Summaries for Beta-Glucopyranoside Tasting

OMIM : 57 Among the 5 taste modalities recognized by humans (bitter, sweet, sour, umami, and salty), bitter taste plays an important protective role because many plant toxins have a bitter taste. The G protein-coupled receptor encoded by TAS2R16 mediates response to salicin, amygdalin, and many bitter beta-glucopyranosides. Beta-glucopyranosides are synthesized by over 2,500 plant and insect species as a protection against predators. This family also includes various toxic cyanogenic glycosides (summary by Soranzo et al., 2005). (617956)

MalaCards based summary : Beta-Glucopyranoside Tasting, is also known as beta-glycopyranoside tasting , (3) alcohol dependence, susceptibility to. An important gene associated with Beta-Glucopyranoside Tasting is TAS2R16 (Taste 2 Receptor Member 16).

Related Diseases for Beta-Glucopyranoside Tasting

Symptoms & Phenotypes for Beta-Glucopyranoside Tasting

Symptoms via clinical synopsis from OMIM:

57
Head And Neck Mouth:
increased sensitivity to bitter taste

Clinical features from OMIM:

617956

Drugs & Therapeutics for Beta-Glucopyranoside Tasting

Search Clinical Trials , NIH Clinical Center for Beta-Glucopyranoside Tasting

Genetic Tests for Beta-Glucopyranoside Tasting

Anatomical Context for Beta-Glucopyranoside Tasting

Publications for Beta-Glucopyranoside Tasting

Articles related to Beta-Glucopyranoside Tasting:

# Title Authors PMID Year
1
Origin and differential selection of allelic variation at TAS2R16 associated with salicin bitter taste sensitivity in Africa. 8 71
24177185 2014
2
Positive selection on a high-sensitivity allele of the human bitter-taste receptor TAS2R16. 8 71
16051168 2005
3
Functional variants in TAS2R38 and TAS2R16 influence alcohol consumption in high-risk families of African-American origin. 71
17250611 2007
4
Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence. 71
16385453 2006
5
Alcoholism susceptibility loci: confirmation studies in a replicate sample and further mapping. 71
10923994 2000
6
Genome-wide search for genes affecting the risk for alcohol dependence. 71
9603606 1998

Variations for Beta-Glucopyranoside Tasting

ClinVar genetic disease variations for Beta-Glucopyranoside Tasting:

6
# Gene Variation Type Significance SNP ID GRCh37 Pos GRCh38 Pos
1 TAS2R16 NM_016945.3(TAS2R16): c.516T> G (p.Asn172Lys) single nucleotide variant risk factor rs846664 7:122635173-122635173 7:122995119-122995119

Expression for Beta-Glucopyranoside Tasting

Search GEO for disease gene expression data for Beta-Glucopyranoside Tasting.

Pathways for Beta-Glucopyranoside Tasting

GO Terms for Beta-Glucopyranoside Tasting

Sources for Beta-Glucopyranoside Tasting

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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